Pub Date : 2021-06-01Epub Date: 2021-06-14DOI: 10.1007/978-3-030-78191-0_13
Min Zhang, Dongsheng An, Na Lei, Jianfeng Wu, Tong Zhao, Xiaoyin Xu, Yalin Wang, Xianfeng Gu
Biomarkers play an important role in early detection and intervention in Alzheimer's disease (AD). However, obtaining effective biomarkers for AD is still a big challenge. In this work, we propose to use the worst transportation cost as a univariate biomarker to index cortical morphometry for tracking AD progression. The worst transportation (WT) aims to find the least economical way to transport one measure to the other, which contrasts to the optimal transportation (OT) that finds the most economical way between measures. To compute the WT cost, we generalize the Brenier theorem for the OT map to the WT map, and show that the WT map is the gradient of a concave function satisfying the Monge-Ampere equation. We also develop an efficient algorithm to compute the WT map based on computational geometry. We apply the algorithm to analyze cortical shape difference between dementia due to AD and normal aging individuals. The experimental results reveal the effectiveness of our proposed method which yields better statistical performance than other competiting methods including the OT.
{"title":"Cortical Morphometry Analysis based on Worst Transportation Theory.","authors":"Min Zhang, Dongsheng An, Na Lei, Jianfeng Wu, Tong Zhao, Xiaoyin Xu, Yalin Wang, Xianfeng Gu","doi":"10.1007/978-3-030-78191-0_13","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_13","url":null,"abstract":"<p><p>Biomarkers play an important role in early detection and intervention in Alzheimer's disease (AD). However, obtaining effective biomarkers for AD is still a big challenge. In this work, we propose to use the worst transportation cost as a univariate biomarker to index cortical morphometry for tracking AD progression. The worst transportation (WT) aims to find the least economical way to transport one measure to the other, which contrasts to the optimal transportation (OT) that finds the most economical way between measures. To compute the WT cost, we generalize the Brenier theorem for the OT map to the WT map, and show that the WT map is the gradient of a concave function satisfying the Monge-Ampere equation. We also develop an efficient algorithm to compute the WT map based on computational geometry. We apply the algorithm to analyze cortical shape difference between dementia due to AD and normal aging individuals. The experimental results reveal the effectiveness of our proposed method which yields better statistical performance than other competiting methods including the OT.</p>","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":" ","pages":"163-176"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291742/pdf/nihms-1689887.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39206848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.1007/978-3-030-78191-0_19
Naresh Nandakumar, K. Manzoor, S. Agarwal, J. Pillai, S. Gujar, H. Sair, A. Venkataraman
{"title":"A Multi-scale Spatial and Temporal Attention Network on Dynamic Connectivity to Localize the Eloquent Cortex in Brain Tumor Patients","authors":"Naresh Nandakumar, K. Manzoor, S. Agarwal, J. Pillai, S. Gujar, H. Sair, A. Venkataraman","doi":"10.1007/978-3-030-78191-0_19","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_19","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"12729 1","pages":"241-252"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48604772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-15DOI: 10.1007/978-3-030-78191-0_15
Maëliss Jallais, P. Rodrigues, Alexandre Gramfort, D. Wassermann
{"title":"Cytoarchitecture Measurements in Brain Gray Matter Using Likelihood-Free Inference","authors":"Maëliss Jallais, P. Rodrigues, Alexandre Gramfort, D. Wassermann","doi":"10.1007/978-3-030-78191-0_15","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_15","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"22 1","pages":"191-202"},"PeriodicalIF":0.0,"publicationDate":"2021-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91257956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-13DOI: 10.1007/978-3-030-78191-0_30
Fan Wang, S. Kapse, Steven Liu, P. Prasanna, Chao Chen
{"title":"TopoTxR: A Topological Biomarker for Predicting Treatment Response in Breast Cancer","authors":"Fan Wang, S. Kapse, Steven Liu, P. Prasanna, Chao Chen","doi":"10.1007/978-3-030-78191-0_30","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_30","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"8 1","pages":"386-397"},"PeriodicalIF":0.0,"publicationDate":"2021-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75460357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-12DOI: 10.1007/978-3-030-78191-0_52
Mobarakol Islam, B. Glocker
{"title":"Spatially Varying Label Smoothing: Capturing Uncertainty from Expert Annotations","authors":"Mobarakol Islam, B. Glocker","doi":"10.1007/978-3-030-78191-0_52","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_52","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"42 1","pages":"677-688"},"PeriodicalIF":0.0,"publicationDate":"2021-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78107449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-31DOI: 10.1007/978-3-030-78191-0_9
Shuo Han, Samuel W. Remedios, A. Carass, M. Schar, Jerry L Prince
{"title":"MR Slice Profile Estimation by Learning to Match Internal Patch Distributions","authors":"Shuo Han, Samuel W. Remedios, A. Carass, M. Schar, Jerry L Prince","doi":"10.1007/978-3-030-78191-0_9","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_9","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"52 1","pages":"108-119"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85884655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-24DOI: 10.1007/978-3-030-78191-0_27
Lianrui Zuo, B. Dewey, A. Carass, Yihao Liu, Yufan He, P. Calabresi, Jerry L Prince
{"title":"Information-based Disentangled Representation Learning for Unsupervised MR Harmonization","authors":"Lianrui Zuo, B. Dewey, A. Carass, Yihao Liu, Yufan He, P. Calabresi, Jerry L Prince","doi":"10.1007/978-3-030-78191-0_27","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_27","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"8 1 1","pages":"346-359"},"PeriodicalIF":0.0,"publicationDate":"2021-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83680741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-19DOI: 10.1007/978-3-030-78191-0_26
Tom van Sonsbeek, Xiantong Zhen, M. Worring, Ling Shao
{"title":"Variational Knowledge Distillation for Disease Classification in Chest X-Rays","authors":"Tom van Sonsbeek, Xiantong Zhen, M. Worring, Ling Shao","doi":"10.1007/978-3-030-78191-0_26","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_26","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"30 1","pages":"334-345"},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90165994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-19DOI: 10.1007/978-3-030-78191-0_33
L. Xie, L. Wisse, Jiancong Wang, S. Ravikumar, T. Glenn, A. Luther, Sydney A. Lim, D. Wolk, Paul Yushkevich
{"title":"Deep Label Fusion: A 3D End-to-End Hybrid Multi-Atlas Segmentation and Deep Learning Pipeline","authors":"L. Xie, L. Wisse, Jiancong Wang, S. Ravikumar, T. Glenn, A. Luther, Sydney A. Lim, D. Wolk, Paul Yushkevich","doi":"10.1007/978-3-030-78191-0_33","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_33","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"26 1","pages":"428-439"},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83291736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-18DOI: 10.1007/978-3-030-78191-0_41
Xiaojie Gao, Yueming Jin, Zixu Zhao, Q. Dou, P. Heng
{"title":"Future Frame Prediction for Robot-assisted Surgery","authors":"Xiaojie Gao, Yueming Jin, Zixu Zhao, Q. Dou, P. Heng","doi":"10.1007/978-3-030-78191-0_41","DOIUrl":"https://doi.org/10.1007/978-3-030-78191-0_41","url":null,"abstract":"","PeriodicalId":73379,"journal":{"name":"Information processing in medical imaging : proceedings of the ... conference","volume":"3 1","pages":"533-544"},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86184670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}