Ross E Michaels, Chelsey A Witsberger, A. Powell, Krishna Koka, Katheryn Cohen, Z. Nourmohammadi, G. Green, D. Zopf
Ross Michaels‡ ,1 , Chelsey A Witsberger‡ ,2 , Allison R Powell1 , Krishna Koka3, Katheryn Cohen4, Zahra Nourmohammadi3,5, Glen E Green5 & David A Zopf*,3,5 1Medical School, University of Michigan, Ann Arbor, MI 48109, USA 2Medical School, Indiana University, Indianapolis, IN 46202, USA 3Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA 4Washington University in St Louis, St Louis, MO 63130, USA 5Department of Otolaryngology – Head & Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA *Author for correspondence: Tel.: +1 734 936 4934; davidzop@med.umich.edu ‡Co-first authors
Ross Michaels‡，1,chelsea A Witsberger‡，2,Allison R Powell1, Krishna Koka3, Katheryn Cohen4, Zahra nourmohammadi3,5, Glen E Green5和David A Zopf*，3,5 1密西根大学医学院，密西根州安娜堡48109，美国2印第安纳州印第安纳波利斯医学院，印第安纳州46202，美国3密西根大学生物医学工程系，密西根州安娜堡48109，美国4华盛顿大学圣路易斯分校，密苏里州圣路易斯63130，美国5耳耳喉-头颈外科，*通讯作者:电话:+1 734 936 4934;davidzop@med.umich.edu共同第一作者
{"title":"3D printing in surgical simulation: emphasized importance in the COVID-19 pandemic era","authors":"Ross E Michaels, Chelsey A Witsberger, A. Powell, Krishna Koka, Katheryn Cohen, Z. Nourmohammadi, G. Green, D. Zopf","doi":"10.2217/3dp-2021-0009","DOIUrl":"https://doi.org/10.2217/3dp-2021-0009","url":null,"abstract":"Ross Michaels‡ ,1 , Chelsey A Witsberger‡ ,2 , Allison R Powell1 , Krishna Koka3, Katheryn Cohen4, Zahra Nourmohammadi3,5, Glen E Green5 & David A Zopf*,3,5 1Medical School, University of Michigan, Ann Arbor, MI 48109, USA 2Medical School, Indiana University, Indianapolis, IN 46202, USA 3Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA 4Washington University in St Louis, St Louis, MO 63130, USA 5Department of Otolaryngology – Head & Neck Surgery, University of Michigan, Ann Arbor, MI 48109, USA *Author for correspondence: Tel.: +1 734 936 4934; davidzop@med.umich.edu ‡Co-first authors","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"247 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77594428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Radfar, S. R. Bazaz, F. Mirakhorli, M. Warkiani
Along with the COVID-19 pandemic, urgent needs for medical and specialized products, especially personal protective equipment, has been overwhelming. The conventional production line of medical devices has been challenged by excessive global demand, and the need for an easy, low-cost and rapid fabrication method is felt more than ever. In a scramble to address this shortfall, manufacturers referred to additive manufacturing or 3D printing to fill the gap and increase the production line of medical devices. Various previously/conventionally fabricated designs have been modified and redesigned to suit the 3D printing requirement to fight against COVID-19. In this perspective, various designs accommodated for the current worldwide outbreak of COVID-19 are discussed and how 3D printing could help the global community against the current and future conditions has been explored.
{"title":"The role of 3D printing in the fight against COVID-19 outbreak","authors":"P. Radfar, S. R. Bazaz, F. Mirakhorli, M. Warkiani","doi":"10.2217/3dp-2020-0028","DOIUrl":"https://doi.org/10.2217/3dp-2020-0028","url":null,"abstract":"Along with the COVID-19 pandemic, urgent needs for medical and specialized products, especially personal protective equipment, has been overwhelming. The conventional production line of medical devices has been challenged by excessive global demand, and the need for an easy, low-cost and rapid fabrication method is felt more than ever. In a scramble to address this shortfall, manufacturers referred to additive manufacturing or 3D printing to fill the gap and increase the production line of medical devices. Various previously/conventionally fabricated designs have been modified and redesigned to suit the 3D printing requirement to fight against COVID-19. In this perspective, various designs accommodated for the current worldwide outbreak of COVID-19 are discussed and how 3D printing could help the global community against the current and future conditions has been explored.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86098703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tweetable abstract #3Dprinting assumed a fundamental role during the #covid-19 #pandemic worldwide. It establishes as a notorious manufacturing technique in the industry and society and a powerful ally for #future emergencies.
{"title":"COVID-19 and the worldwide actions to mitigate its effects using 3D printing","authors":"G. A. Longhitano, Jorge Vicente Lopes da Silva","doi":"10.2217/3dp-2021-0004","DOIUrl":"https://doi.org/10.2217/3dp-2021-0004","url":null,"abstract":"Tweetable abstract #3Dprinting assumed a fundamental role during the #covid-19 #pandemic worldwide. It establishes as a notorious manufacturing technique in the industry and society and a powerful ally for #future emergencies.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78546663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Dalla, R. Shinde, J. Ayres, S. Waller, J. Nachtigal
Personal protective equipment (PPE) shortages persist amidst increasing COVID-19 caseloads. These shortages encouraged some to pursue 3D printing to produce stopgap N95 alternatives. The design presented is an adapter for a commercially available snorkel mask to serve as a full-face respirator, used in dire PPE shortages or in individuals who failed fit testing. Masks were fit tested at The University of Kansas Health System in Kansas City, KS. The mask was fit tested on 22 individuals who previously failed fit testing, and all passed qualitative fit testing with the snorkel mask, adapter and viral filter apparatus. The authors endorse this design as a stopgap measure, proven to be effective in situations of dire PPE shortage or for individuals who have failed fit testing with conventional PPE.
{"title":"3D-printed snorkel mask adapter for failed N95 fit tests and personal protective equipment shortages","authors":"S. Dalla, R. Shinde, J. Ayres, S. Waller, J. Nachtigal","doi":"10.2217/3dp-2020-0018","DOIUrl":"https://doi.org/10.2217/3dp-2020-0018","url":null,"abstract":"Personal protective equipment (PPE) shortages persist amidst increasing COVID-19 caseloads. These shortages encouraged some to pursue 3D printing to produce stopgap N95 alternatives. The design presented is an adapter for a commercially available snorkel mask to serve as a full-face respirator, used in dire PPE shortages or in individuals who failed fit testing. Masks were fit tested at The University of Kansas Health System in Kansas City, KS. The mask was fit tested on 22 individuals who previously failed fit testing, and all passed qualitative fit testing with the snorkel mask, adapter and viral filter apparatus. The authors endorse this design as a stopgap measure, proven to be effective in situations of dire PPE shortage or for individuals who have failed fit testing with conventional PPE.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"1952 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91177915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Dalla, B. Bacon, J. Ayres, S. Holmstead, A. J. Ahlberg Elliot
Personal protective equipment (PPE) shortages represent a persistent and critical challenge during the COVID-19 pandemic. Communities of 3D printing hobbyists and experts responded by designing and producing homemade, 3D-printed PPE. This report discusses the design, manufacturing and validation of the Kansas City Mask (KC Mask). Once printed and assembled, masks were fit tested at Truman Medical Center in Kansas City, MO. The KC Mask was approved for use by pandemic response administration staff at the hospital. Fortunately, due to adequate PPE supply at the time of this publication, wide utilization of the KC mask has not been required. The authors endorse the KC Mask as a stopgap measure, proven to be effective in situations of critical PPE shortage based on Centers for Disease Control and Prevention (CDC) guidelines.
{"title":"3D-printed N95 equivalent for personal protective equipment shortages: the Kansas City Mask","authors":"S. Dalla, B. Bacon, J. Ayres, S. Holmstead, A. J. Ahlberg Elliot","doi":"10.2217/3dp-2020-0019","DOIUrl":"https://doi.org/10.2217/3dp-2020-0019","url":null,"abstract":"Personal protective equipment (PPE) shortages represent a persistent and critical challenge during the COVID-19 pandemic. Communities of 3D printing hobbyists and experts responded by designing and producing homemade, 3D-printed PPE. This report discusses the design, manufacturing and validation of the Kansas City Mask (KC Mask). Once printed and assembled, masks were fit tested at Truman Medical Center in Kansas City, MO. The KC Mask was approved for use by pandemic response administration staff at the hospital. Fortunately, due to adequate PPE supply at the time of this publication, wide utilization of the KC mask has not been required. The authors endorse the KC Mask as a stopgap measure, proven to be effective in situations of critical PPE shortage based on Centers for Disease Control and Prevention (CDC) guidelines.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"390 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77764357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. A. Longhitano, Geovany Candido, Leonardo Mendes Ribeiro Machado, P. Neto, M. F. de Oliveira, P. Noritomi, Francisco Guilherme Mais, Victor Luiz de Paula Souza, Jorge Vicente Lopes da Silva
Aim: To produce valves to be used with full-face snorkeling masks for noninvasive ventilation (NIV) procedure during the coronavirus disease 2019 (COVID-19) pandemic. Materials & methods: ISINNOVA’s Charlotte valves for full-face snorkeling masks used for NIV procedures were redesigned, produced by selective laser sintering additive manufacturing, and submitted to air leakage tests. Results: The final model assembly did not present air leakage during the NIV procedure on human models, minimizing risks of air contamination. Conclusion: This study shows the feasibility of using additive manufactured valves with snorkel facial masks to support health systems during COVID-19 and possible future pandemics.
{"title":"3D-printed valves to assist noninvasive ventilation procedures during the COVID-19 pandemic: a case study","authors":"G. A. Longhitano, Geovany Candido, Leonardo Mendes Ribeiro Machado, P. Neto, M. F. de Oliveira, P. Noritomi, Francisco Guilherme Mais, Victor Luiz de Paula Souza, Jorge Vicente Lopes da Silva","doi":"10.2217/3dp-2020-0017","DOIUrl":"https://doi.org/10.2217/3dp-2020-0017","url":null,"abstract":"Aim: To produce valves to be used with full-face snorkeling masks for noninvasive ventilation (NIV) procedure during the coronavirus disease 2019 (COVID-19) pandemic. Materials & methods: ISINNOVA’s Charlotte valves for full-face snorkeling masks used for NIV procedures were redesigned, produced by selective laser sintering additive manufacturing, and submitted to air leakage tests. Results: The final model assembly did not present air leakage during the NIV procedure on human models, minimizing risks of air contamination. Conclusion: This study shows the feasibility of using additive manufactured valves with snorkel facial masks to support health systems during COVID-19 and possible future pandemics.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81821194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Severe acute respiratory syndrome coronavirus 2, a novel coronavirus, caused global disruption specifically in linear supply chains. Increased demand for already disrupted services led to a global shortage of medical equipment and personal protective equipment. Use of additive manufacturing (AM) processes by the manufacturing community has shown great innovation, agility and flexibility to fill supply chain gaps and meet shortfalls. In the context of contingency reaction to a global healthcare emergency, decisions have had to be made quickly, in some cases bypassing device safety regulations. This concentrated and spontaneous use of AM has highlighted the challenges and risks of such innovation, which we discuss in relation to the UK’s current regulatory landscape. We have discussed lessons learned and the potential future impact upon wider use of AM in healthcare.
{"title":"COVID-19: additive manufacturing response in the UK","authors":"Elen J Parry, C. Banks","doi":"10.2217/3dp-2020-0013","DOIUrl":"https://doi.org/10.2217/3dp-2020-0013","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2, a novel coronavirus, caused global disruption specifically in linear supply chains. Increased demand for already disrupted services led to a global shortage of medical equipment and personal protective equipment. Use of additive manufacturing (AM) processes by the manufacturing community has shown great innovation, agility and flexibility to fill supply chain gaps and meet shortfalls. In the context of contingency reaction to a global healthcare emergency, decisions have had to be made quickly, in some cases bypassing device safety regulations. This concentrated and spontaneous use of AM has highlighted the challenges and risks of such innovation, which we discuss in relation to the UK’s current regulatory landscape. We have discussed lessons learned and the potential future impact upon wider use of AM in healthcare.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79617566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Powell, Charles A. Keilin, Ross E Michaels, Owen J Tien, K. VanKoevering, G. Green, D. Zopf
{"title":"Pivoting: from academic 3D printing to rapid COVID-19 solutions","authors":"A. Powell, Charles A. Keilin, Ross E Michaels, Owen J Tien, K. VanKoevering, G. Green, D. Zopf","doi":"10.2217/3dp-2020-0022","DOIUrl":"https://doi.org/10.2217/3dp-2020-0022","url":null,"abstract":"","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75138323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sven Duda, Sascha Hartig, K. Hagner, Lisa Meyer, Paula Wessling Intriago, T. Meyer, H. Wessling
Background: In 2020, the severe acute respiratory syndrome coronavirus 2 pandemic caused serious concerns about the availability of face masks. This paper studies the technical feasibility of user-specific face mask production by 3D printing and the effectiveness of these masks. Material & methods: Six different face mask designs were produced by 3D printing and tested by subjective experimenter evaluation and using a respirator fit testing kit. Results were compared with the requirements as given for standard protective face masks. Results: None of the printed masks came anywhere near the required standards for personal protective gear. Conclusion: In spite of their euphoric presentation in the press, none of the currently advertised 3D printed mask designs are suitable as reliable personal protective equipment.
{"title":"Potential risks of a widespread use of 3D printing for the manufacturing of face masks during the severe acute respiratory syndrome coronavirus 2 pandemic","authors":"Sven Duda, Sascha Hartig, K. Hagner, Lisa Meyer, Paula Wessling Intriago, T. Meyer, H. Wessling","doi":"10.2217/3dp-2020-0014","DOIUrl":"https://doi.org/10.2217/3dp-2020-0014","url":null,"abstract":"Background: In 2020, the severe acute respiratory syndrome coronavirus 2 pandemic caused serious concerns about the availability of face masks. This paper studies the technical feasibility of user-specific face mask production by 3D printing and the effectiveness of these masks. Material & methods: Six different face mask designs were produced by 3D printing and tested by subjective experimenter evaluation and using a respirator fit testing kit. Results were compared with the requirements as given for standard protective face masks. Results: None of the printed masks came anywhere near the required standards for personal protective gear. Conclusion: In spite of their euphoric presentation in the press, none of the currently advertised 3D printed mask designs are suitable as reliable personal protective equipment.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72765528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The most common and malignant primary brain tumor in adults is glioblastoma (GBM). In vitro 3D brain models are needed to better understand the pathological processes underlying GBM and ultimately develop more efficient antineoplastic agents. Here, we describe the bioprinting methods that have been used to fabricate volumetric GBM models. We explain several factors that should be considered for 3D bioprinting, including bioinks, cells and construct designs, in relation to GBM modeling. Although 3D-bioprinted brain models are still to be improved, they have the potential to become a powerful tool for drug screening.
{"title":"3D bioprinting of glioblastoma models.","authors":"Carolina Parra-Cantu, Wanlu Li, Alfredo Quiñones-Hinojosa, Yu Shrike Zhang","doi":"10.2217/3dp-2019-0027","DOIUrl":"https://doi.org/10.2217/3dp-2019-0027","url":null,"abstract":"<p><p>The most common and malignant primary brain tumor in adults is glioblastoma (GBM). <i>In vitro</i> 3D brain models are needed to better understand the pathological processes underlying GBM and ultimately develop more efficient antineoplastic agents. Here, we describe the bioprinting methods that have been used to fabricate volumetric GBM models. We explain several factors that should be considered for 3D bioprinting, including bioinks, cells and construct designs, in relation to GBM modeling. Although 3D-bioprinted brain models are still to be improved, they have the potential to become a powerful tool for drug screening.</p>","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"4 2","pages":"113-125"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/3dp-2019-0027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38619498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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