The author thank the financial support provided through the project NanOptoNerv (PTDC/NAN-MAT/29936/2017), financed bythe Portuguese Foundation for Science and Technology (FCT) and COMPETE 2020. This work has been cofunded through theproject 06242IQBIONEURO6, Fundo Europeu de Desenvolvimento Regional (FEDER) through the Program Interreg V-A Espa na-Portugal (POCTEP) 2014–2020. The FCT distinction attributed to JM Oliveira (IF/01285/2015) under the Investigator FCT programis also greatly acknowledged. The author has no other relevant affiliations or financial involvement with any organization or entitywith a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
作者感谢NanOptoNerv项目(PTDC/ nanan - mat /29936/2017)提供的资金支持,该项目由葡萄牙科学技术基金会(FCT)和COMPETE 2020资助。这项工作由欧洲区域环境保护基金会(FEDER)通过2014-2020年西班牙-葡萄牙Interreg计划(POCTEP)共同资助。JM Oliveira (IF/01285/2015)在研究者FCT项目中获得的FCT荣誉也得到了极大的认可。除了那些披露的内容外,作者与任何组织或实体没有其他相关的从属关系或财务参与,这些组织或实体与手稿中讨论的主题或材料有经济利益或经济冲突。
{"title":"Current and future trends of silk fibroin-based bioinks in 3D printing","authors":"J. Oliveira","doi":"10.2217/3dp-2020-0005","DOIUrl":"https://doi.org/10.2217/3dp-2020-0005","url":null,"abstract":"The author thank the financial support provided through the project NanOptoNerv (PTDC/NAN-MAT/29936/2017), financed bythe Portuguese Foundation for Science and Technology (FCT) and COMPETE 2020. This work has been cofunded through theproject 06242IQBIONEURO6, Fundo Europeu de Desenvolvimento Regional (FEDER) through the Program Interreg V-A Espa na-Portugal (POCTEP) 2014–2020. The FCT distinction attributed to JM Oliveira (IF/01285/2015) under the Investigator FCT programis also greatly acknowledged. The author has no other relevant affiliations or financial involvement with any organization or entitywith a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90961808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To position medical 3D printing practices, risk and governance as more complex than mere manufacturing so to consider the contextual network-enabled dilemmas from remediating and remanufacturing the body in professional clinical and pedagogical practice; to suggest the current regulatory logics of risk and innovation do not sufficiently acknowledge shifts to network-enabled practitioner collaborations, exemplified here via ‘chilling effects’ of closed intellectual property regimes. Methods & framework: Anonymous practitioner workshop (n:12), socio-legal critique. Results: Communicated need to acknowledge practices of medical 3D printing under socio-legal constraints. Conclusion: Consider 3D printing as communication models to sustain medical research-practice in a digital–physical age, including consideration of novel governance mechanisms such as practitioner licensing and building a medical commons with network-friendly intellectual property regime.
{"title":"Positioning innovation and governance for 3D printing in clinical care: an Australian case","authors":"Luke Heemsbergen, R. Fordyce","doi":"10.2217/3dp-2019-0008","DOIUrl":"https://doi.org/10.2217/3dp-2019-0008","url":null,"abstract":"Aim: To position medical 3D printing practices, risk and governance as more complex than mere manufacturing so to consider the contextual network-enabled dilemmas from remediating and remanufacturing the body in professional clinical and pedagogical practice; to suggest the current regulatory logics of risk and innovation do not sufficiently acknowledge shifts to network-enabled practitioner collaborations, exemplified here via ‘chilling effects’ of closed intellectual property regimes. Methods & framework: Anonymous practitioner workshop (n:12), socio-legal critique. Results: Communicated need to acknowledge practices of medical 3D printing under socio-legal constraints. Conclusion: Consider 3D printing as communication models to sustain medical research-practice in a digital–physical age, including consideration of novel governance mechanisms such as practitioner licensing and building a medical commons with network-friendly intellectual property regime.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78761618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Spinal brace wear time affects treatment effectiveness of adolescent idiopathic scoliosis but remains challenging with the brace’s bulkiness. This study aims to determine the appropriate material and thickness to improve wear comfort. Materials & methods: Thirty-one specimens were tested with 13 ULTEM1010 and 13 Nylon12 potential materials and 5 standard polypropylene material in 2.5, 3.25 and 4 mm thicknesses to evaluate mechanical properties. Donning tests of ULTEM1010 and Nylon12 printed braces were conducted. Results: Nylon12 with 2.5–3.25 mm thickness had higher flexibility and the closest mechanical characteristics as 4-mm thick polypropylene. ULTEM1010 brace fractured after 615-times and Nylon12 brace handled 2920-times of opening and closing. Conclusion: Nylon12, 2.5–3.25 mm are appropriate design parameters. Further clinical study can validate long term brace effectiveness.
{"title":"Investigation of future 3D printed brace design parameters: evaluation of mechanical properties and prototype outcomes","authors":"K. Ng, K. Duke, E. Lou","doi":"10.2217/3dp-2019-0012","DOIUrl":"https://doi.org/10.2217/3dp-2019-0012","url":null,"abstract":"Aim: Spinal brace wear time affects treatment effectiveness of adolescent idiopathic scoliosis but remains challenging with the brace’s bulkiness. This study aims to determine the appropriate material and thickness to improve wear comfort. Materials & methods: Thirty-one specimens were tested with 13 ULTEM1010 and 13 Nylon12 potential materials and 5 standard polypropylene material in 2.5, 3.25 and 4 mm thicknesses to evaluate mechanical properties. Donning tests of ULTEM1010 and Nylon12 printed braces were conducted. Results: Nylon12 with 2.5–3.25 mm thickness had higher flexibility and the closest mechanical characteristics as 4-mm thick polypropylene. ULTEM1010 brace fractured after 615-times and Nylon12 brace handled 2920-times of opening and closing. Conclusion: Nylon12, 2.5–3.25 mm are appropriate design parameters. Further clinical study can validate long term brace effectiveness.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87784223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This review summarizes the utility of 3D-printing as a surgical adjunct, reviewing the cost–effectiveness. The relevant literature was analyzed outlining the utility and/or cost–effectiveness of 3D-printing for clinical use. Compared with existing methods, the evidence suggests an advantage of using 3D-printing as a technology in the treatment of complex clinical cases. However, in high frequency cases, the additional preoperative expenses are not justified. Considerable evidence of its clinical benefits exists for the application of 3D-printed anatomical models and teaching tools. However, the evidence supporting 3D-printing’s use as surgical guides or implantable devices is less clear. Furthermore, caution must exist when using these devices in the clinical setting due to a paucity of rigorous testing, global regulation and long-term data.
{"title":"Utility and cost–effectiveness of 3D-printed materials for clinical use","authors":"Julian Vitali, M. Cheng, M. Wagels","doi":"10.2217/3dp-2019-0015","DOIUrl":"https://doi.org/10.2217/3dp-2019-0015","url":null,"abstract":"This review summarizes the utility of 3D-printing as a surgical adjunct, reviewing the cost–effectiveness. The relevant literature was analyzed outlining the utility and/or cost–effectiveness of 3D-printing for clinical use. Compared with existing methods, the evidence suggests an advantage of using 3D-printing as a technology in the treatment of complex clinical cases. However, in high frequency cases, the additional preoperative expenses are not justified. Considerable evidence of its clinical benefits exists for the application of 3D-printed anatomical models and teaching tools. However, the evidence supporting 3D-printing’s use as surgical guides or implantable devices is less clear. Furthermore, caution must exist when using these devices in the clinical setting due to a paucity of rigorous testing, global regulation and long-term data.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74170479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D printing for the planning and use in complicated surgical procedures: an interview with Juling Ong","authors":"J. Ong","doi":"10.2217/3dp-2019-0023","DOIUrl":"https://doi.org/10.2217/3dp-2019-0023","url":null,"abstract":"","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79106100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Presurgical application of nasoalveolar molding (NAM) appliances, which direct tissues closer together as the patient grows, can facilitate surgical repair of cleft lip and palate in some cases. Fabrication of the appliances with conventional techniques requires considerable time and clinical expertise to guide the tissues while mitigating undesired effects such as growth restriction. Computer-aided workflows harnessing digital models, virtual treatment planning and 3D printing have evolved over the past decade to increase the efficiency of NAM therapy with a series of appliances. This narrative review highlights different workflows applying 3D printing technologies to enable production of tangible parts from the virtual treatment plan and discusses how advances in the computational methods and printing materials may enable new horizons for computer-aided NAM therapy.
{"title":"Emerging applications of 3D printing in nasoalveolar molding therapy: a narrative review","authors":"F. Kasper, Meredith M Ghivizzani, Brett T Chiquet","doi":"10.2217/3dp-2019-0019","DOIUrl":"https://doi.org/10.2217/3dp-2019-0019","url":null,"abstract":"Presurgical application of nasoalveolar molding (NAM) appliances, which direct tissues closer together as the patient grows, can facilitate surgical repair of cleft lip and palate in some cases. Fabrication of the appliances with conventional techniques requires considerable time and clinical expertise to guide the tissues while mitigating undesired effects such as growth restriction. Computer-aided workflows harnessing digital models, virtual treatment planning and 3D printing have evolved over the past decade to increase the efficiency of NAM therapy with a series of appliances. This narrative review highlights different workflows applying 3D printing technologies to enable production of tangible parts from the virtual treatment plan and discusses how advances in the computational methods and printing materials may enable new horizons for computer-aided NAM therapy.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"75 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77387995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. G. Moulic, Sanjoy Singh, R. Hussain, Girish Murthy, Yash Khawade, Nakul Bettaiah
The field of rehabilitation and assistive technology has witnessed various approaches and changes in the course of its evolution. Traditional materials like wood or heavy metals have been replaced by resins and plastics. The need to deliver assistive devices has quickly resulted in the creation of new technologies like 3D printing and digital transformation, internet of things IoT. This article addresses the development of applying digital transformation and 3D printing techniques to produce socket designs for weight bearing transtibial prosthetic system. It also focus on efficacy of the load-bearing transtibial sockets, design philosophies involved, materials used and the forthcoming challenges. This initiative involves experienced clinical prosthetists, product designers, digital modelers and additive manufacturing engineers working toward this application.
{"title":"Digital transformation and 3D printing of transtibial load-bearing prosthesis in India: recent advances, challenges and future perspectives","authors":"S. G. Moulic, Sanjoy Singh, R. Hussain, Girish Murthy, Yash Khawade, Nakul Bettaiah","doi":"10.2217/3dp-2019-0013","DOIUrl":"https://doi.org/10.2217/3dp-2019-0013","url":null,"abstract":"The field of rehabilitation and assistive technology has witnessed various approaches and changes in the course of its evolution. Traditional materials like wood or heavy metals have been replaced by resins and plastics. The need to deliver assistive devices has quickly resulted in the creation of new technologies like 3D printing and digital transformation, internet of things IoT. This article addresses the development of applying digital transformation and 3D printing techniques to produce socket designs for weight bearing transtibial prosthetic system. It also focus on efficacy of the load-bearing transtibial sockets, design philosophies involved, materials used and the forthcoming challenges. This initiative involves experienced clinical prosthetists, product designers, digital modelers and additive manufacturing engineers working toward this application.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87008222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01Epub Date: 2019-08-21DOI: 10.2217/3dp-2019-0016
Sossena Wood, Tiago Martins, Tamer S Ibrahim
In this paper, we will provide a methodology for head phantom development based on in vivo imaging data attained utilizing MRI. The anthropomorphic phantom can be designed to mimic human anatomy.
{"title":"How to design and construct a 3D-printed human head phantom.","authors":"Sossena Wood, Tiago Martins, Tamer S Ibrahim","doi":"10.2217/3dp-2019-0016","DOIUrl":"https://doi.org/10.2217/3dp-2019-0016","url":null,"abstract":"<p><p>In this paper, we will provide a methodology for head phantom development based on <i>in vivo</i> imaging data attained utilizing MRI. The anthropomorphic phantom can be designed to mimic human anatomy.</p>","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"3 3","pages":"119-125"},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/3dp-2019-0016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37536895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr Rohan Shirwaiker is an associate professor in the Fitts Department of Industrial and Systems Engineering and an associate faculty in the Joint Department of Biomedical Engineering, Center for Additive Manufacturing and Logistics, and Comparative Medicine Institute at NC State University. He directs activities of the 3D Tissue Manufacturing research group which focuses on scalable 3D biofabrication technologies. Dr Shirwaiker has received recognitions including the NSF CAREER Award and SME Outstanding Young Manufacturing Engineer Award. He currently serves on the Advisory Board of IISE's Manufacturing & Design division and on the Scientific Committee of North American Manufacturing Research Institution of SME. In this exclusive interview, Rohan Shirwaiker discusses his current research on the use of ultrasound in bioprinting. This interview was conducted by Mike Gregg, Commissioning Editor for the Journal of 3D Printing in Medicine.
{"title":"Bioprinting with ultrasound","authors":"Rohan A. Shirwaiker","doi":"10.2217/3DP-2019-0017","DOIUrl":"https://doi.org/10.2217/3DP-2019-0017","url":null,"abstract":"Dr Rohan Shirwaiker is an associate professor in the Fitts Department of Industrial and Systems Engineering and an associate faculty in the Joint Department of Biomedical Engineering, Center for Additive Manufacturing and Logistics, and Comparative Medicine Institute at NC State University. He directs activities of the 3D Tissue Manufacturing research group which focuses on scalable 3D biofabrication technologies. Dr Shirwaiker has received recognitions including the NSF CAREER Award and SME Outstanding Young Manufacturing Engineer Award. He currently serves on the Advisory Board of IISE's Manufacturing & Design division and on the Scientific Committee of North American Manufacturing Research Institution of SME. In this exclusive interview, Rohan Shirwaiker discusses his current research on the use of ultrasound in bioprinting. This interview was conducted by Mike Gregg, Commissioning Editor for the Journal of 3D Printing in Medicine.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84222144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Sahal, Mu Chen, Shruti Sharma, Sidharth Sukumaran Nair, Vaishakh Gopalakrishnan Nair
The current approach of modifying standardized prosthetics for orthopedic, dental and maxillofacial implants made from conventional manufacturing techniques have been found inconvenient to customize for specific cases as the complex geometry of the skeletal tissue varies appreciably from patient to patient [ 1 , 2 ]. These standard procedures justly demand patient-specific, complex-shaped, custom-made implants be reliably delivered in minimal time. In this specific regard, 3DP implants are extensively researched [ 3 ]. A significant number of research outcomes sufficiently emphasize the desirable superior shape conformity and the short delivery time provided by the custom-made 3DP implants compared over conventional implants. These potential benefits facilitated by the novel 3DP technology can be adequately explained by the inherent ability of various modern 3DP disciplines to manufacture complex shaped implants by efficiently converting any patient-specific x-ray or CT scans into STL files. In this academic paper, we comparatively review the methods and materials utilized for specific 3DP implants.
{"title":"3DP materials and methods for orthopedic, dental and maxillofacial implants: a brief comparative report","authors":"Mohammed Sahal, Mu Chen, Shruti Sharma, Sidharth Sukumaran Nair, Vaishakh Gopalakrishnan Nair","doi":"10.2217/3DP-2018-0020","DOIUrl":"https://doi.org/10.2217/3DP-2018-0020","url":null,"abstract":"The current approach of modifying standardized prosthetics for orthopedic, dental and maxillofacial implants made from conventional manufacturing techniques have been found inconvenient to customize for specific cases as the complex geometry of the skeletal tissue varies appreciably from patient to patient [ 1 , 2 ]. These standard procedures justly demand patient-specific, complex-shaped, custom-made implants be reliably delivered in minimal time. In this specific regard, 3DP implants are extensively researched [ 3 ]. A significant number of research outcomes sufficiently emphasize the desirable superior shape conformity and the short delivery time provided by the custom-made 3DP implants compared over conventional implants. These potential benefits facilitated by the novel 3DP technology can be adequately explained by the inherent ability of various modern 3DP disciplines to manufacture complex shaped implants by efficiently converting any patient-specific x-ray or CT scans into STL files. In this academic paper, we comparatively review the methods and materials utilized for specific 3DP implants.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"200 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81081702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}