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Journal of 3D printing in medicine最新文献

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Current and future trends of silk fibroin-based bioinks in 3D printing 基于丝素蛋白的生物墨水在3D打印中的现状和未来趋势
Pub Date : 2020-06-01 DOI: 10.2217/3dp-2020-0005
J. Oliveira
The author thank the financial support provided through the project NanOptoNerv (PTDC/NAN-MAT/29936/2017), financed bythe Portuguese Foundation for Science and Technology (FCT) and COMPETE 2020. This work has been cofunded through theproject 06242IQBIONEURO6, Fundo Europeu de Desenvolvimento Regional (FEDER) through the Program Interreg V-A Espa na-Portugal (POCTEP) 2014–2020. The FCT distinction attributed to JM Oliveira (IF/01285/2015) under the Investigator FCT programis also greatly acknowledged. The author has no other relevant affiliations or financial involvement with any organization or entitywith a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
作者感谢NanOptoNerv项目(PTDC/ nanan - mat /29936/2017)提供的资金支持,该项目由葡萄牙科学技术基金会(FCT)和COMPETE 2020资助。这项工作由欧洲区域环境保护基金会(FEDER)通过2014-2020年西班牙-葡萄牙Interreg计划(POCTEP)共同资助。JM Oliveira (IF/01285/2015)在研究者FCT项目中获得的FCT荣誉也得到了极大的认可。除了那些披露的内容外,作者与任何组织或实体没有其他相关的从属关系或财务参与,这些组织或实体与手稿中讨论的主题或材料有经济利益或经济冲突。
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引用次数: 10
Positioning innovation and governance for 3D printing in clinical care: an Australian case 3D打印在临床护理中的定位创新和治理:一个澳大利亚案例
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0008
Luke Heemsbergen, R. Fordyce
Aim: To position medical 3D printing practices, risk and governance as more complex than mere manufacturing so to consider the contextual network-enabled dilemmas from remediating and remanufacturing the body in professional clinical and pedagogical practice; to suggest the current regulatory logics of risk and innovation do not sufficiently acknowledge shifts to network-enabled practitioner collaborations, exemplified here via ‘chilling effects’ of closed intellectual property regimes. Methods & framework: Anonymous practitioner workshop (n:12), socio-legal critique. Results: Communicated need to acknowledge practices of medical 3D printing under socio-legal constraints. Conclusion: Consider 3D printing as communication models to sustain medical research-practice in a digital–physical age, including consideration of novel governance mechanisms such as practitioner licensing and building a medical commons with network-friendly intellectual property regime.
目的:将医疗3D打印实践,风险和治理定位为比单纯的制造更复杂,以便考虑在专业临床和教学实践中修复和再制造身体的上下文网络支持困境;建议当前的风险和创新监管逻辑没有充分承认向网络驱动的从业者合作的转变,这里通过封闭知识产权制度的“寒蝉效应”举例说明。方法和框架:匿名从业者研讨会(n:12),社会法律批判。结果:沟通需要承认在社会法律约束下的医疗3D打印实践。结论:考虑将3D打印作为在数字物理时代维持医学研究实践的交流模式,包括考虑新的治理机制,如从业者许可和建立具有网络友好知识产权制度的医疗公地。
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引用次数: 1
Investigation of future 3D printed brace design parameters: evaluation of mechanical properties and prototype outcomes 未来3D打印支架设计参数的研究:机械性能和原型结果的评估
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0012
K. Ng, K. Duke, E. Lou
Aim: Spinal brace wear time affects treatment effectiveness of adolescent idiopathic scoliosis but remains challenging with the brace’s bulkiness. This study aims to determine the appropriate material and thickness to improve wear comfort. Materials & methods: Thirty-one specimens were tested with 13 ULTEM1010 and 13 Nylon12 potential materials and 5 standard polypropylene material in 2.5, 3.25 and 4 mm thicknesses to evaluate mechanical properties. Donning tests of ULTEM1010 and Nylon12 printed braces were conducted. Results: Nylon12 with 2.5–3.25 mm thickness had higher flexibility and the closest mechanical characteristics as 4-mm thick polypropylene. ULTEM1010 brace fractured after 615-times and Nylon12 brace handled 2920-times of opening and closing. Conclusion: Nylon12, 2.5–3.25 mm are appropriate design parameters. Further clinical study can validate long term brace effectiveness.
目的:脊柱支架的佩戴时间影响青少年特发性脊柱侧凸的治疗效果,但由于支架的体积较大,仍然具有挑战性。本研究旨在确定合适的材料和厚度,以提高穿着舒适性。材料与方法:用13种ULTEM1010和13种Nylon12电位材料和5种2.5、3.25和4 mm厚度的标准聚丙烯材料对31个试样进行力学性能测试。对ULTEM1010和尼龙12打印牙套进行了佩戴试验。结果:2.5 ~ 3.25 mm厚度的尼龙具有更高的柔韧性,力学特性与4 mm厚度的聚丙烯最接近。ULTEM1010支架断裂615次,尼龙12支架断裂2920次。结论:尼龙12、2.5 ~ 3.25 mm为适宜的设计参数。进一步的临床研究可以验证支具的长期有效性。
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引用次数: 8
Utility and cost–effectiveness of 3D-printed materials for clinical use 临床使用3d打印材料的效用和成本效益
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0015
Julian Vitali, M. Cheng, M. Wagels
This review summarizes the utility of 3D-printing as a surgical adjunct, reviewing the cost–effectiveness. The relevant literature was analyzed outlining the utility and/or cost–effectiveness of 3D-printing for clinical use. Compared with existing methods, the evidence suggests an advantage of using 3D-printing as a technology in the treatment of complex clinical cases. However, in high frequency cases, the additional preoperative expenses are not justified. Considerable evidence of its clinical benefits exists for the application of 3D-printed anatomical models and teaching tools. However, the evidence supporting 3D-printing’s use as surgical guides or implantable devices is less clear. Furthermore, caution must exist when using these devices in the clinical setting due to a paucity of rigorous testing, global regulation and long-term data.
这篇综述总结了3d打印作为外科辅助工具的效用,回顾了成本效益。分析了相关文献,概述了临床使用3d打印的实用性和/或成本效益。与现有方法相比,有证据表明,使用3d打印技术治疗复杂的临床病例具有优势。然而,在高频率的病例中,额外的术前费用是不合理的。大量证据表明其临床效益存在于3d打印解剖模型和教学工具的应用中。然而,支持3d打印用作手术指南或植入式设备的证据还不太清楚。此外,由于缺乏严格的测试、全球监管和长期数据,在临床环境中使用这些设备时必须谨慎。
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引用次数: 7
3D printing for the planning and use in complicated surgical procedures: an interview with Juling Ong 3D打印在复杂外科手术中的规划和应用:王巨玲访谈
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0023
J. Ong
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引用次数: 1
Emerging applications of 3D printing in nasoalveolar molding therapy: a narrative review 3D打印在鼻肺泡成型治疗中的新兴应用:叙述性回顾
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0019
F. Kasper, Meredith M Ghivizzani, Brett T Chiquet
Presurgical application of nasoalveolar molding (NAM) appliances, which direct tissues closer together as the patient grows, can facilitate surgical repair of cleft lip and palate in some cases. Fabrication of the appliances with conventional techniques requires considerable time and clinical expertise to guide the tissues while mitigating undesired effects such as growth restriction. Computer-aided workflows harnessing digital models, virtual treatment planning and 3D printing have evolved over the past decade to increase the efficiency of NAM therapy with a series of appliances. This narrative review highlights different workflows applying 3D printing technologies to enable production of tangible parts from the virtual treatment plan and discusses how advances in the computational methods and printing materials may enable new horizons for computer-aided NAM therapy.
手术前应用鼻牙槽成型(NAM)器具,它可以引导组织在患者生长时更紧密地结合在一起,在某些情况下可以促进唇腭裂的手术修复。使用传统技术制造矫治器需要相当长的时间和临床专业知识来引导组织,同时减轻诸如生长限制等不良影响。利用数字模型、虚拟治疗计划和3D打印的计算机辅助工作流程在过去十年中得到了发展,通过一系列设备提高了NAM治疗的效率。本文重点介绍了应用3D打印技术从虚拟治疗计划中生产有形部件的不同工作流程,并讨论了计算方法和打印材料的进步如何为计算机辅助NAM治疗带来新的前景。
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引用次数: 1
Digital transformation and 3D printing of transtibial load-bearing prosthesis in India: recent advances, challenges and future perspectives 印度胫骨承重假体的数字化转型和3D打印:最新进展、挑战和未来展望
Pub Date : 2019-11-01 DOI: 10.2217/3dp-2019-0013
S. G. Moulic, Sanjoy Singh, R. Hussain, Girish Murthy, Yash Khawade, Nakul Bettaiah
The field of rehabilitation and assistive technology has witnessed various approaches and changes in the course of its evolution. Traditional materials like wood or heavy metals have been replaced by resins and plastics. The need to deliver assistive devices has quickly resulted in the creation of new technologies like 3D printing and digital transformation, internet of things IoT. This article addresses the development of applying digital transformation and 3D printing techniques to produce socket designs for weight bearing transtibial prosthetic system. It also focus on efficacy of the load-bearing transtibial sockets, design philosophies involved, materials used and the forthcoming challenges. This initiative involves experienced clinical prosthetists, product designers, digital modelers and additive manufacturing engineers working toward this application.
康复和辅助技术领域在其发展过程中经历了各种方法和变化。木材或重金属等传统材料已被树脂和塑料所取代。对辅助设备的需求迅速催生了3D打印、数字化转型、物联网等新技术。本文讨论了应用数字转换和3D打印技术来生产承重胫骨假体系统的插座设计的发展。它还侧重于承重胫骨套的功效,所涉及的设计理念,使用的材料和即将面临的挑战。这项计划涉及经验丰富的临床义肢专家、产品设计师、数字建模师和增材制造工程师。
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引用次数: 4
How to design and construct a 3D-printed human head phantom. 如何设计和构建一个3d打印的人类头部幻影。
Pub Date : 2019-08-01 Epub Date: 2019-08-21 DOI: 10.2217/3dp-2019-0016
Sossena Wood, Tiago Martins, Tamer S Ibrahim

In this paper, we will provide a methodology for head phantom development based on in vivo imaging data attained utilizing MRI. The anthropomorphic phantom can be designed to mimic human anatomy.

在本文中,我们将提供一种基于利用MRI获得的体内成像数据的头部幻影开发方法。拟人化的幻影可以被设计成模仿人体解剖结构。
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引用次数: 5
Bioprinting with ultrasound 超声波生物打印
Pub Date : 2019-08-01 DOI: 10.2217/3DP-2019-0017
Rohan A. Shirwaiker
Dr Rohan Shirwaiker is an associate professor in the Fitts Department of Industrial and Systems Engineering and an associate faculty in the Joint Department of Biomedical Engineering, Center for Additive Manufacturing and Logistics, and Comparative Medicine Institute at NC State University. He directs activities of the 3D Tissue Manufacturing research group which focuses on scalable 3D biofabrication technologies. Dr Shirwaiker has received recognitions including the NSF CAREER Award and SME Outstanding Young Manufacturing Engineer Award. He currently serves on the Advisory Board of IISE's Manufacturing & Design division and on the Scientific Committee of North American Manufacturing Research Institution of SME. In this exclusive interview, Rohan Shirwaiker discusses his current research on the use of ultrasound in bioprinting. This interview was conducted by Mike Gregg, Commissioning Editor for the Journal of 3D Printing in Medicine.
Rohan Shirwaiker博士是北卡州立大学工业与系统工程系副教授,也是生物医学工程系、增材制造与物流中心和比较医学研究所的副教授。他指导3D组织制造研究小组的活动,该小组专注于可扩展的3D生物制造技术。Shirwaiker博士获得了包括NSF CAREER奖和SME杰出青年制造工程师奖在内的认可。他目前是IISE制造与设计部门的顾问委员会成员,也是北美中小企业制造研究所科学委员会成员。在这次独家采访中,Rohan Shirwaiker讨论了他目前在生物打印中使用超声波的研究。这次采访是由医学3D打印杂志的委托编辑Mike Gregg进行的。
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引用次数: 0
3DP materials and methods for orthopedic, dental and maxillofacial implants: a brief comparative report 骨科,牙科和颌面种植体的3d打印材料和方法:一个简短的比较报告
Pub Date : 2019-08-01 DOI: 10.2217/3DP-2018-0020
Mohammed Sahal, Mu Chen, Shruti Sharma, Sidharth Sukumaran Nair, Vaishakh Gopalakrishnan Nair
The current approach of modifying standardized prosthetics for orthopedic, dental and maxillofacial implants made from conventional manufacturing techniques have been found inconvenient to customize for specific cases as the complex geometry of the skeletal tissue varies appreciably from patient to patient [ 1 , 2 ]. These standard procedures justly demand patient-specific, complex-shaped, custom-made implants be reliably delivered in minimal time. In this specific regard, 3DP implants are extensively researched [ 3 ]. A significant number of research outcomes sufficiently emphasize the desirable superior shape conformity and the short delivery time provided by the custom-made 3DP implants compared over conventional implants. These potential benefits facilitated by the novel 3DP technology can be adequately explained by the inherent ability of various modern 3DP disciplines to manufacture complex shaped implants by efficiently converting any patient-specific x-ray or CT scans into STL files. In this academic paper, we comparatively review the methods and materials utilized for specific 3DP implants.
由于骨组织的复杂几何形状因患者而异,目前使用传统制造技术对骨科、牙科和颌面植入物的标准化修复体进行修改的方法已被发现不方便针对特定病例进行定制[1,2]。这些标准程序要求在最短的时间内可靠地交付患者特定的、形状复杂的、定制的植入物。在这方面,3d打印植入物被广泛研究[3]。大量的研究结果充分强调了与传统种植体相比,定制的3d打印种植体具有理想的形状一致性和较短的交付时间。新型3d打印技术带来的这些潜在好处可以通过各种现代3d打印学科的固有能力来充分解释,通过有效地将任何患者特定的x射线或CT扫描转换为STL文件来制造复杂形状的植入物。在这篇学术论文中,我们比较回顾了用于特定3d打印植入物的方法和材料。
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引用次数: 7
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Journal of 3D printing in medicine
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