C. Serrano, Hélène Van den Brink, J. Pineau, P. Prognon, N. Martelli
Aim: The evaluation of a health technology determines the clinical and non clinical value of the technology. Among the non clinical criteria, evaluation models include the organizational impact (OI) of the technology. The objective of this study is to highlight the types of OIs of 3D printing in a hospital setting. Materials & methods: A panel of 12 experts was assembled based on their knowledge of 3D printed medical devices and then interviewed individually. Results: A strong consensus was reached for three types of impacts out of the 12 types of OIs associated with medical devices: the need for training, cooperation and communication and the logistics circuit. Conclusion: It seems very relevant to integrate these three types of impacts in future evaluations of 3D printing in healthcare.
{"title":"Organizational impact of 3D printing technology in surgery: which criteria to evaluate?","authors":"C. Serrano, Hélène Van den Brink, J. Pineau, P. Prognon, N. Martelli","doi":"10.2217/3dp-2021-0023","DOIUrl":"https://doi.org/10.2217/3dp-2021-0023","url":null,"abstract":"Aim: The evaluation of a health technology determines the clinical and non clinical value of the technology. Among the non clinical criteria, evaluation models include the organizational impact (OI) of the technology. The objective of this study is to highlight the types of OIs of 3D printing in a hospital setting. Materials & methods: A panel of 12 experts was assembled based on their knowledge of 3D printed medical devices and then interviewed individually. Results: A strong consensus was reached for three types of impacts out of the 12 types of OIs associated with medical devices: the need for training, cooperation and communication and the logistics circuit. Conclusion: It seems very relevant to integrate these three types of impacts in future evaluations of 3D printing in healthcare.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79150331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Bhatt, P. Sharma, Upadhyayula Suryanarayana Murty, Subhamoy Banerjee
Aim: The significant critical barrier in the ascension of fused deposition modeling (FDM) into a scalable technology is the lack of defined quality benchmarks for validating filament performance. To avoid this issue, we aimed to create a comprehensive quantitative approach providing a road map to evaluate the fabricated filament for successful FDM 3D printing. Materials & methods: A detailed in vitro physico-technological analysis including axial as well as oscillatory stress tests were performed to validate the melt-extruded filament. Results & conclusion: The results from the above noted tests as well as microscopic examinations suggested toward the superiority of 6.5% plasticizer-loaded drug-polymer filaments in terms of mechanical prerequisites like feedability, extrudability and printability, as well as complete molecular homogenization.
{"title":"Systematic evaluations of melt-extruded filament for fused deposition modeling-mediated 3D printing","authors":"U. Bhatt, P. Sharma, Upadhyayula Suryanarayana Murty, Subhamoy Banerjee","doi":"10.2217/3dp-2021-0031","DOIUrl":"https://doi.org/10.2217/3dp-2021-0031","url":null,"abstract":"Aim: The significant critical barrier in the ascension of fused deposition modeling (FDM) into a scalable technology is the lack of defined quality benchmarks for validating filament performance. To avoid this issue, we aimed to create a comprehensive quantitative approach providing a road map to evaluate the fabricated filament for successful FDM 3D printing. Materials & methods: A detailed in vitro physico-technological analysis including axial as well as oscillatory stress tests were performed to validate the melt-extruded filament. Results & conclusion: The results from the above noted tests as well as microscopic examinations suggested toward the superiority of 6.5% plasticizer-loaded drug-polymer filaments in terms of mechanical prerequisites like feedability, extrudability and printability, as well as complete molecular homogenization.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79027061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mashaal Syed, Nathaniel Neavling, Brandon L Mariotti, Adedayo Adetunji, Jennifer Z. Mao, Slah Khan, J. Mullin
Given the limitations of cadavers, 3D printing has the potential to improve development of human cervical spine models for use in medical educational and surgical case preparation. A literature review of quantitative biomechanical specifications such as Young’s Modulus and Poisson’s ratio, as well as qualitative components of major anatomical aspects of the human spine was performed. Datasheets from seven thermoplastic manufacturers were compiled to review the specifications and mechanical properties of their materials. Suggested thermoplastics were assigned to specific anatomical features of the cervical spine according to their respective biomechanical properties and presented. Commercially available materials and techniques exist to simulate the investigated anatomical components of the cervical spine as a cost-effective 3D-printed model with biomechanical accuracy.
{"title":"Materials review: 3D printing a biomechanically accurate cervical spine model for surgical education and case preparation","authors":"Mashaal Syed, Nathaniel Neavling, Brandon L Mariotti, Adedayo Adetunji, Jennifer Z. Mao, Slah Khan, J. Mullin","doi":"10.2217/3dp-2021-0029","DOIUrl":"https://doi.org/10.2217/3dp-2021-0029","url":null,"abstract":"Given the limitations of cadavers, 3D printing has the potential to improve development of human cervical spine models for use in medical educational and surgical case preparation. A literature review of quantitative biomechanical specifications such as Young’s Modulus and Poisson’s ratio, as well as qualitative components of major anatomical aspects of the human spine was performed. Datasheets from seven thermoplastic manufacturers were compiled to review the specifications and mechanical properties of their materials. Suggested thermoplastics were assigned to specific anatomical features of the cervical spine according to their respective biomechanical properties and presented. Commercially available materials and techniques exist to simulate the investigated anatomical components of the cervical spine as a cost-effective 3D-printed model with biomechanical accuracy.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73286374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The preliminary safety and accuracy of a modified 3D-printed reconstruction plate (3DPRP) for mandible segmental defects were evaluated. Two patients with mandible segmental defects who underwent reconstruction using 3DPRPs were included in the study. No dead space, wound healing failures or fractures were observed. The mean deviations for the two patients were 0.59 and 0.57 mm and the condyle changes were 1.01 and 0.88 mm. The deviations in the distances between both sides of the mandibles (D1–6) ranged from 0.67 to 1.16 mm and from 0.43 to 0.61 mm for the two patients. The preliminary results show that the modified 3DPRPs are safe and accurate.
{"title":"The use of modified 3D-printed reconstruction plates in mandible segmental defect rehabilitation: a case report","authors":"Yi-Wei Zhong, Zuoxiang Wang, Wenjian Wu, J. Zhang","doi":"10.2217/3dp-2021-0032","DOIUrl":"https://doi.org/10.2217/3dp-2021-0032","url":null,"abstract":"The preliminary safety and accuracy of a modified 3D-printed reconstruction plate (3DPRP) for mandible segmental defects were evaluated. Two patients with mandible segmental defects who underwent reconstruction using 3DPRPs were included in the study. No dead space, wound healing failures or fractures were observed. The mean deviations for the two patients were 0.59 and 0.57 mm and the condyle changes were 1.01 and 0.88 mm. The deviations in the distances between both sides of the mandibles (D1–6) ranged from 0.67 to 1.16 mm and from 0.43 to 0.61 mm for the two patients. The preliminary results show that the modified 3DPRPs are safe and accurate.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"10 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72499101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Guillemin, G. Dipasquale, Johannes WE Uiterwijk, M. Jaccard, Orane Lorton, P. Tsoutsou, J. Gariani, P. Poletti, R. Salomir, T. Zilli
Aim: To test 3D-printed immobilization device for future use in magnetic resonance-guided focused ultrasound hyperthermia. Material & methods: Using a surface scanner, patient-specific pelvic immobilization devices were 3D printed. The setup reproducibility was measured both on linear accelerator (LINAC) and magnetic resonance. An ultrasound imaging probe was used to acquire reference images and later to acquire images once attached into the embedded holder. Results: Prepositioning accuracy was tested at LINAC using an optical surface monitoring and MRI and showed submillimeter accuracy and small angular rotations. Agreement was high between the ultrasound reference images versus the immobilized probe. Conclusion: Reported results are considered as a promising step toward a fast and precise positioning of patients and an easier integration of radiotherapy and magnetic resonance-guided focused ultrasound hyperthermia.
{"title":"Magnetic resonance-guided ultrasound hyperthermia for prostate cancer radiotherapy: an immobilization device embedding the ultrasound applicator","authors":"P. Guillemin, G. Dipasquale, Johannes WE Uiterwijk, M. Jaccard, Orane Lorton, P. Tsoutsou, J. Gariani, P. Poletti, R. Salomir, T. Zilli","doi":"10.2217/3dp-2021-0024","DOIUrl":"https://doi.org/10.2217/3dp-2021-0024","url":null,"abstract":"Aim: To test 3D-printed immobilization device for future use in magnetic resonance-guided focused ultrasound hyperthermia. Material & methods: Using a surface scanner, patient-specific pelvic immobilization devices were 3D printed. The setup reproducibility was measured both on linear accelerator (LINAC) and magnetic resonance. An ultrasound imaging probe was used to acquire reference images and later to acquire images once attached into the embedded holder. Results: Prepositioning accuracy was tested at LINAC using an optical surface monitoring and MRI and showed submillimeter accuracy and small angular rotations. Agreement was high between the ultrasound reference images versus the immobilized probe. Conclusion: Reported results are considered as a promising step toward a fast and precise positioning of patients and an easier integration of radiotherapy and magnetic resonance-guided focused ultrasound hyperthermia.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78572938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ross E Michaels, Chelsey A Witsberger, Mitchell D Cin, Nicholas V Zugris, Djordje Jaksic, Kevin Wen, Z. Nourmohammadi, D. Zopf
Aim: Orofacial clefts are prevalent with limited access to surgical correction. To address this issue our objective was to create a low-cost, high-fidelity, 3D-printed Veau class II cleft palate surgical simulator. Materials & methods: A 3D-printed Veau class II cleft palate simulator was designed using de-identified computed tomography data and computer aided design software. The simulator then underwent multi-institutional expert otolaryngologist validation. Results: The Veau class II cleft palate simulator was rated on a scale of 1–5; 3.8 as a training tool, 4.20 as a competency evaluation tool and 4.20 as a rehearsal tool. The simulator was also rated as very relevant (4.20) and very useful (4.60). Conclusion: The low-cost, high-fidelity Veau II cleft palate simulator was rated highly for physical attributes, realism, performance and usefulness.
{"title":"Development of a high-fidelity, 3D-printed Veau class II cleft palate simulator with patient-specific capabilities","authors":"Ross E Michaels, Chelsey A Witsberger, Mitchell D Cin, Nicholas V Zugris, Djordje Jaksic, Kevin Wen, Z. Nourmohammadi, D. Zopf","doi":"10.2217/3dp-2021-0027","DOIUrl":"https://doi.org/10.2217/3dp-2021-0027","url":null,"abstract":"Aim: Orofacial clefts are prevalent with limited access to surgical correction. To address this issue our objective was to create a low-cost, high-fidelity, 3D-printed Veau class II cleft palate surgical simulator. Materials & methods: A 3D-printed Veau class II cleft palate simulator was designed using de-identified computed tomography data and computer aided design software. The simulator then underwent multi-institutional expert otolaryngologist validation. Results: The Veau class II cleft palate simulator was rated on a scale of 1–5; 3.8 as a training tool, 4.20 as a competency evaluation tool and 4.20 as a rehearsal tool. The simulator was also rated as very relevant (4.20) and very useful (4.60). Conclusion: The low-cost, high-fidelity Veau II cleft palate simulator was rated highly for physical attributes, realism, performance and usefulness.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90551136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gemma Traynor, Andrew Iu Shearn, Elena G Milano, Maria Victoria Ordonez, Mari Nieves Velasco Forte, Massimo Caputo, Silvia Schievano, Hannah Mustard, Jo Wray, Giovanni Biglino
3D models have been used as an asset in many clinical applications and a variety of disciplines, and yet the available literature studying the use of 3D models in communication is limited. This scoping review has been conducted to draw conclusions on the current evidence and learn from previous studies, using this knowledge to inform future work. Our search strategy revealed 269 papers, 19 of which were selected for final inclusion and analysis. When assessing the use of 3D models in doctor-patient communication, there is a need for larger studies and studies including a long-term follow up. Furthermore, there are forms of communication that are yet to be researched and provide a niche that may be beneficial to explore.
{"title":"The use of 3D-printed models in patient communication: a scoping review.","authors":"Gemma Traynor, Andrew Iu Shearn, Elena G Milano, Maria Victoria Ordonez, Mari Nieves Velasco Forte, Massimo Caputo, Silvia Schievano, Hannah Mustard, Jo Wray, Giovanni Biglino","doi":"10.2217/3dp-2021-0021","DOIUrl":"https://doi.org/10.2217/3dp-2021-0021","url":null,"abstract":"<p><p>3D models have been used as an asset in many clinical applications and a variety of disciplines, and yet the available literature studying the use of 3D models in communication is limited. This scoping review has been conducted to draw conclusions on the current evidence and learn from previous studies, using this knowledge to inform future work. Our search strategy revealed 269 papers, 19 of which were selected for final inclusion and analysis. When assessing the use of 3D models in doctor-patient communication, there is a need for larger studies and studies including a long-term follow up. Furthermore, there are forms of communication that are yet to be researched and provide a niche that may be beneficial to explore.</p>","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"6 1","pages":"13-23"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8852361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9144109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kier M. Blevins, R. Danilkowicz, Amanda N. Fletcher, N. Allen, L. Johnson, Samuel Olorunfemi Adams
Annually, millions of Americans require some form of reconstructive surgery as the result of a traumatic injury, degenerative process or pathologic state. In the field of orthopedic surgery, the gold standard for augmenting bone, cartilage and soft tissue defects has been through the application of grafts, prostheses and soft-tissue flaps. Recently, there have been great advances within the field of tissue engineering including the development of 3D-bioprinting technology. Bioprinting uses biomaterials and cells to create 3D tissue-mimicking structures aimed at repairing or replacing damaged tissues. Further developments have led to in situ bioprinting which manufactures the tissue directly at the site of repair through handheld or portable 3D-bioprinting devices. Challenges still exist in implementing this technology. However, there is hope that one day this technology will be equipped for the operating room or clinic.
{"title":"In situ 3D bioprinting of musculoskeletal tissues in orthopedic surgery","authors":"Kier M. Blevins, R. Danilkowicz, Amanda N. Fletcher, N. Allen, L. Johnson, Samuel Olorunfemi Adams","doi":"10.2217/3dp-2021-0022","DOIUrl":"https://doi.org/10.2217/3dp-2021-0022","url":null,"abstract":"Annually, millions of Americans require some form of reconstructive surgery as the result of a traumatic injury, degenerative process or pathologic state. In the field of orthopedic surgery, the gold standard for augmenting bone, cartilage and soft tissue defects has been through the application of grafts, prostheses and soft-tissue flaps. Recently, there have been great advances within the field of tissue engineering including the development of 3D-bioprinting technology. Bioprinting uses biomaterials and cells to create 3D tissue-mimicking structures aimed at repairing or replacing damaged tissues. Further developments have led to in situ bioprinting which manufactures the tissue directly at the site of repair through handheld or portable 3D-bioprinting devices. Challenges still exist in implementing this technology. However, there is hope that one day this technology will be equipped for the operating room or clinic.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78484698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew J. Brown, R. Danilkowicz, Samuel Olorunfemi Adams
Aim: Post-traumatic large critical bone defects remain a challenge for today’s orthopedist. Despite multiple available options for treatment including autograft, massive allograft and various methods of bone transport, no strategy has shown itself to be free of significant complications or discouraging rates of nonunion and other mechanisms of failure. Case presentation: Here, we present a patient example of successful treatment of critical bone defect of the distal tibia utilizing the novel technology of a 3D-printed titanium cage coupled with a combination of autologous and allogenic bone graft in a 26-year-old male injured in motor vehicle collision. Conclusion: This case provides further evidence of a successful and promising new treatment to address these challenging injuries.
{"title":"Patient-specific 3D-printed titanium implant for distal tibial critical bone defect","authors":"Matthew J. Brown, R. Danilkowicz, Samuel Olorunfemi Adams","doi":"10.2217/3dp-2021-0025","DOIUrl":"https://doi.org/10.2217/3dp-2021-0025","url":null,"abstract":"Aim: Post-traumatic large critical bone defects remain a challenge for today’s orthopedist. Despite multiple available options for treatment including autograft, massive allograft and various methods of bone transport, no strategy has shown itself to be free of significant complications or discouraging rates of nonunion and other mechanisms of failure. Case presentation: Here, we present a patient example of successful treatment of critical bone defect of the distal tibia utilizing the novel technology of a 3D-printed titanium cage coupled with a combination of autologous and allogenic bone graft in a 26-year-old male injured in motor vehicle collision. Conclusion: This case provides further evidence of a successful and promising new treatment to address these challenging injuries.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91121320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tweetable abstract New material combinations provide potential for major improvements in #3D printing/#AdditiveManufacturing, but how do we get started with them and what are the potential stumbling blocks? Find out here!
{"title":"Making our parts work harder – getting started with functional materials for 3D printing","authors":"C. Majewski","doi":"10.2217/3dp-2021-0030","DOIUrl":"https://doi.org/10.2217/3dp-2021-0030","url":null,"abstract":"Tweetable abstract New material combinations provide potential for major improvements in #3D printing/#AdditiveManufacturing, but how do we get started with them and what are the potential stumbling blocks? Find out here!","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73856842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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