Μemory by itself as a function, loses its capabilities with a normal deterioration. However, there are acquired conditions that negatively affect the functions of memory, resulting in dysfunction of its stages. Thus possible damage to the structures of the hemisphere that controls these processes disrupts the comprehension, organization and categorization of the material to be memorized. Patients with damage to these systems will have difficulty remembering because they have not adequately coded the material. Patients with Multiple Sclerosis report short-term memory difficulties in the sense that they have difficulty remembering details of recent conversations and events. Aim: To investigate the memory storage difficulties in Multiple Sclerosis. Materials and Methods: An international literature review was performed on Memory Disorders in Multiple Sclerosis. Conclusion: In patients with Multiple Sclerosis learning deficits are greatly aided by processing speed and working memory. It has been observed that slow mental processing makes it difficult for many patients with Multiple Sclerosis to capture an entire verbal message, especially if it is large, complex, delivered quickly and with external stimuli, such as a noisy environment
{"title":"Investigating memory storage difficulties in Multiple Sclerosis","authors":"T. Antonis","doi":"10.31579/2578-8868/185","DOIUrl":"https://doi.org/10.31579/2578-8868/185","url":null,"abstract":"Μemory by itself as a function, loses its capabilities with a normal deterioration. However, there are acquired conditions that negatively affect the functions of memory, resulting in dysfunction of its stages. Thus possible damage to the structures of the hemisphere that controls these processes disrupts the comprehension, organization and categorization of the material to be memorized. Patients with damage to these systems will have difficulty remembering because they have not adequately coded the material. Patients with Multiple Sclerosis report short-term memory difficulties in the sense that they have difficulty remembering details of recent conversations and events. Aim: To investigate the memory storage difficulties in Multiple Sclerosis. Materials and Methods: An international literature review was performed on Memory Disorders in Multiple Sclerosis. Conclusion: In patients with Multiple Sclerosis learning deficits are greatly aided by processing speed and working memory. It has been observed that slow mental processing makes it difficult for many patients with Multiple Sclerosis to capture an entire verbal message, especially if it is large, complex, delivered quickly and with external stimuli, such as a noisy environment","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49193955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Surgery for applying the auditory brainstem implant is an otoneurosurgery that requires careful intraoperative monitoring to optimize the placement of the electrode paddle. This study aimed to validate a new method capable of increasing the accuracy of electrode array placement, reducing channel interaction, electrical artefacts, and saturation effects, and providing the largest number of electrodes that can be activated with the lowest possible electric charge. Materials and methods: Thirty-six subjects aged between 1.42 and 69.92 years were tested during surgery for auditory brainstem implantation. We recorded auditory electrical responses of the brainstem using the implant supplier's suggested stimulation protocol and the new protocol. Results: Saturations effects and electric artefacts were noticed respectively in 81.85% and 53.25% of recordings using implant supplier's method, while in 70.34% and 24.75% of recordings using the new method, with a percentage variation of 11.51% and 28.50%. Considering the amount of charge required to activate the electrodes, with the implant supplier's method an average charge of 14 nC was needed, while with the new protocol an average charge of 8 nC was necessary. Conclusions: The new method improves the coupling between the auditory brainstem implant and the surface of the cochlear nucleus.
{"title":"New Protocol for Auditory Brainstem Implant Positioning","authors":"S. Veronese, M. Cambiaghi, A. Sbarbati","doi":"10.31579/2578-8868/203","DOIUrl":"https://doi.org/10.31579/2578-8868/203","url":null,"abstract":"Background: Surgery for applying the auditory brainstem implant is an otoneurosurgery that requires careful intraoperative monitoring to optimize the placement of the electrode paddle. This study aimed to validate a new method capable of increasing the accuracy of electrode array placement, reducing channel interaction, electrical artefacts, and saturation effects, and providing the largest number of electrodes that can be activated with the lowest possible electric charge. Materials and methods: Thirty-six subjects aged between 1.42 and 69.92 years were tested during surgery for auditory brainstem implantation. We recorded auditory electrical responses of the brainstem using the implant supplier's suggested stimulation protocol and the new protocol. Results: Saturations effects and electric artefacts were noticed respectively in 81.85% and 53.25% of recordings using implant supplier's method, while in 70.34% and 24.75% of recordings using the new method, with a percentage variation of 11.51% and 28.50%. Considering the amount of charge required to activate the electrodes, with the implant supplier's method an average charge of 14 nC was needed, while with the new protocol an average charge of 8 nC was necessary. Conclusions: The new method improves the coupling between the auditory brainstem implant and the surface of the cochlear nucleus.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47384096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-28DOI: 10.21203/rs.3.rs-1016602/v1
J. Zou, Xiao-yu Li, Chaojin Han
ObjectiveTo analyze the correlation between the changes of ALP level and the degree of neurological impairment in patients with acute cerebral infarction. MethodsA total of 267 patients with acute cerebral infarction were selected as the cerebral infarction group, 181 elderly patients who were matched age and gender in the same period with the cerebral infarction group were selected as the control group by the physical examination. All the selected patients were tested for serum ALP, ALT, AST, Cr, BUN,TG, TC, LDL - C and HDL - C after eight hours on an empty stomach. In the 72nd hour of the patient's course of cerebral infarction, the degree of neurological impairment was assessed using NIHSS score. The relationship between serum ALP level and NIHSS score was analyzed. ResultsAccording to NIHSS score, the patients with score of 5~15 were Group A , patients with score of 15~20 were Group B and score of 21~42 were Group C. Pearson correlation analysis showed that the serum ALP level of the three groups was positively correlated with NIHSS score. Multivariate regression analysis results showed that the high serum ALP level of the risk of cerebral infarction is a low serum ALP level 1.58 times. ConclusionsSerum ALP level was increased in patients with acute cerebral infarction and was closely related to the degree of neurological impairment. Perhaps the serum ALP level may be used as a serum marker to predict the degree of neurological impairment in patients.
{"title":"The Predictive Value of Serum Alkaline Phosphatase Level on the Degree of Neurological Impairment in Patients With Acute Cerebral Infarction","authors":"J. Zou, Xiao-yu Li, Chaojin Han","doi":"10.21203/rs.3.rs-1016602/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-1016602/v1","url":null,"abstract":"\u0000 ObjectiveTo analyze the correlation between the changes of ALP level and the degree of neurological impairment in patients with acute cerebral infarction. MethodsA total of 267 patients with acute cerebral infarction were selected as the cerebral infarction group, 181 elderly patients who were matched age and gender in the same period with the cerebral infarction group were selected as the control group by the physical examination. All the selected patients were tested for serum ALP, ALT, AST, Cr, BUN,TG, TC, LDL - C and HDL - C after eight hours on an empty stomach. In the 72nd hour of the patient's course of cerebral infarction, the degree of neurological impairment was assessed using NIHSS score. The relationship between serum ALP level and NIHSS score was analyzed. ResultsAccording to NIHSS score, the patients with score of 5~15 were Group A , patients with score of 15~20 were Group B and score of 21~42 were Group C. Pearson correlation analysis showed that the serum ALP level of the three groups was positively correlated with NIHSS score. Multivariate regression analysis results showed that the high serum ALP level of the risk of cerebral infarction is a low serum ALP level 1.58 times. ConclusionsSerum ALP level was increased in patients with acute cerebral infarction and was closely related to the degree of neurological impairment. Perhaps the serum ALP level may be used as a serum marker to predict the degree of neurological impairment in patients.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46395523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psychiatry is, indeed, basically similar to the rest of medicine. It is based upon making reliable diagnoses and applying evidence - based treatments that have success rates comparable with those used in other specialties. Psychiatric syndromes may be defined as disorders that are conventionally treated with treatments used by psychiatrists. The illnesses in which psychiatrists have developed proficiency have tended to be those that either manifest with disordered psychological functioning (thinking, perception, emotion, and memory) or those which have no obviously established organic basis. However, scientific developments are showing us that these so - called psychological ailments are linked with abnormalities of the brain, just as so - called medical illnesses are deeply affected by psychological factors. Modern psychiatry is an evolving field that is becoming less hospital based, more evidence based, and more neuroscience based. Nonetheless, during the last decades, random antipsychiatry attitudes have amalgamated and turned into a conjectural effort, which has a humanistic appearance, too. On the other hand, publicized criticisms by some associates, including known psychiatrists or psychotherapists, have, radically, stirred and reinforced the movement. Anyway, though various criticisms or worries about psychiatry, either as a subdivision in science or as a clinical practice in medicine are understandable due to existing scientific or diagnostic deficits, anti-psychiatry stance, which comprises many historical exaggerations based on happenings and primitive conditions from a century ago, may help to keep us rigorous and honest about what we do and inspiring us to insistently seek better diagnostic prototypes and management standards. In the present article, the said antagonism, in addition to the existing facts and expected responsibilities of psychiatry has been discussed concisely.
{"title":"Psychiatry vs. Antipsychiatry: Facts set against Protests","authors":"S. Shafti","doi":"10.31579/2578-8868/191","DOIUrl":"https://doi.org/10.31579/2578-8868/191","url":null,"abstract":"Psychiatry is, indeed, basically similar to the rest of medicine. It is based upon making reliable diagnoses and applying evidence - based treatments that have success rates comparable with those used in other specialties. Psychiatric syndromes may be defined as disorders that are conventionally treated with treatments used by psychiatrists. The illnesses in which psychiatrists have developed proficiency have tended to be those that either manifest with disordered psychological functioning (thinking, perception, emotion, and memory) or those which have no obviously established organic basis. However, scientific developments are showing us that these so - called psychological ailments are linked with abnormalities of the brain, just as so - called medical illnesses are deeply affected by psychological factors. Modern psychiatry is an evolving field that is becoming less hospital based, more evidence based, and more neuroscience based. Nonetheless, during the last decades, random antipsychiatry attitudes have amalgamated and turned into a conjectural effort, which has a humanistic appearance, too. On the other hand, publicized criticisms by some associates, including known psychiatrists or psychotherapists, have, radically, stirred and reinforced the movement. Anyway, though various criticisms or worries about psychiatry, either as a subdivision in science or as a clinical practice in medicine are understandable due to existing scientific or diagnostic deficits, anti-psychiatry stance, which comprises many historical exaggerations based on happenings and primitive conditions from a century ago, may help to keep us rigorous and honest about what we do and inspiring us to insistently seek better diagnostic prototypes and management standards. In the present article, the said antagonism, in addition to the existing facts and expected responsibilities of psychiatry has been discussed concisely.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47782306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The endovascular clot retrieval in combination with intravenous recombinant tissue plasminogen activator (rtPA) has been established as the 1st choice therapy for the treatment of acute arterial ischemic stroke (AIS) in case of large vessel occlusion. While the results of this therapy in ischemic insults in the anterior stromal region are clearly positive, the results for mechanical thrombectomy in posterior circulation are controversially discussed. In addition, the indication is made by the time window, sizing of the ischemic area, and various scores. The aim of the article is to review the available reports on the use of thromboelastography in acute ischemic stroke patients.
{"title":"Interventional Mechanical thrombectomy Indications and limitations A Mini-Review","authors":"S. Fatehpur","doi":"10.31579/2578-8868/206","DOIUrl":"https://doi.org/10.31579/2578-8868/206","url":null,"abstract":"The endovascular clot retrieval in combination with intravenous recombinant tissue plasminogen activator (rtPA) has been established as the 1st choice therapy for the treatment of acute arterial ischemic stroke (AIS) in case of large vessel occlusion. While the results of this therapy in ischemic insults in the anterior stromal region are clearly positive, the results for mechanical thrombectomy in posterior circulation are controversially discussed. In addition, the indication is made by the time window, sizing of the ischemic area, and various scores. The aim of the article is to review the available reports on the use of thromboelastography in acute ischemic stroke patients.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49600889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of recalibration of the lumbar canal using the Senegas technique guarantees stability and preserves movement, with a considerable reduction in surgical risk and faster incorporation into daily life. Objective: To evaluate the surgical results of recalibration of the lumbar canal using the modified Senegas technique. Materials and Methods: An ambispective and cross-sectional descriptive observational study was carried out at the Institute of Neurology and Neurosurgery between January 2011 and December 2019 that were evaluated 6 and 12 months after having been operated. Results: 70.7% of the patients manifested chronic low back pain, and dysesthesia was found in 39.8%. There were 15.8% complications. The clinical evolution according to the Lumbar and Lower Limb Verbal Numerical Scale and the functional one according to the Oswestry Disability Index was better at 6 and 12 months after the intervention compared to the preoperative period. The result was considered good at 82.7% and 89.4%, respectively, at 6 and 12 months. Conclusions: The clinical and functional evolution of the operated patients is significantly better at 6 and 12 months concerning the preoperative one. At both 6 and 12 months, surgical results are good in the vast majority of patients.
{"title":"Surgical Results of Lumbar Canal Recalibration by Modified Senegas Technique","authors":"N. de la Paz","doi":"10.31579/2578-8868/204","DOIUrl":"https://doi.org/10.31579/2578-8868/204","url":null,"abstract":"The aim of recalibration of the lumbar canal using the Senegas technique guarantees stability and preserves movement, with a considerable reduction in surgical risk and faster incorporation into daily life. Objective: To evaluate the surgical results of recalibration of the lumbar canal using the modified Senegas technique. Materials and Methods: An ambispective and cross-sectional descriptive observational study was carried out at the Institute of Neurology and Neurosurgery between January 2011 and December 2019 that were evaluated 6 and 12 months after having been operated. Results: 70.7% of the patients manifested chronic low back pain, and dysesthesia was found in 39.8%. There were 15.8% complications. The clinical evolution according to the Lumbar and Lower Limb Verbal Numerical Scale and the functional one according to the Oswestry Disability Index was better at 6 and 12 months after the intervention compared to the preoperative period. The result was considered good at 82.7% and 89.4%, respectively, at 6 and 12 months. Conclusions: The clinical and functional evolution of the operated patients is significantly better at 6 and 12 months concerning the preoperative one. At both 6 and 12 months, surgical results are good in the vast majority of patients.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44626970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The neuropsychological training methods for the restoration of sensory losses after a TBI aim both at the restoration of the sensory losses and at the practice of the other senses to "compensate" for the dysfunctional sensation. Aim: The purpose of the study was to present treatment of patients in coma and exercises for enhancing cognitive functions after traumatic brain injury. Results: Electronically assisted treatment methods (Computer - Assisted Treatment, CAT) are now recognized methods, with high success rates in the rehabilitation of patients after TBI. Conclusions: Cognitive rehabilitation must be done taking into account a variety of neurofunctional abilities and weaknesses. Basic skills need to be stimulated before any approach to more complex ones can be made. The use of audiovisual media in general contributes both to the restoration of vision and compensatory restoration of functions as well as to the general restoration of the patient's cognitive functions. Cognitive rehabilitation to recover and improve attention and memory, offers a variety of different types of exercises for specific disorders. Exercise can vary in degree of difficulty depending on the patient's needs.
{"title":"Treatment of Patients in Coma and Exercises for Enhancing Cognitive Functions after Traumatic Brain Injury","authors":"T. Antonis","doi":"10.31579/2578-8868/193","DOIUrl":"https://doi.org/10.31579/2578-8868/193","url":null,"abstract":"The neuropsychological training methods for the restoration of sensory losses after a TBI aim both at the restoration of the sensory losses and at the practice of the other senses to \"compensate\" for the dysfunctional sensation. Aim: The purpose of the study was to present treatment of patients in coma and exercises for enhancing cognitive functions after traumatic brain injury. Results: Electronically assisted treatment methods (Computer - Assisted Treatment, CAT) are now recognized methods, with high success rates in the rehabilitation of patients after TBI. Conclusions: Cognitive rehabilitation must be done taking into account a variety of neurofunctional abilities and weaknesses. Basic skills need to be stimulated before any approach to more complex ones can be made. The use of audiovisual media in general contributes both to the restoration of vision and compensatory restoration of functions as well as to the general restoration of the patient's cognitive functions. Cognitive rehabilitation to recover and improve attention and memory, offers a variety of different types of exercises for specific disorders. Exercise can vary in degree of difficulty depending on the patient's needs.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45473957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This review of the paper ‘‘Entropy, externality and human evolution’’ by G. Iurato and A.Yu. Khrennikov, for the Journal of Neuroscience and Neurological Surgery, is aimed to highlight the main neuroscience and paleo-neurology implications of the theoretical research conducted in such a work, above all in relation to the so-called Radiator Theory of evolution of the brain.
{"title":"‘‘Entropy, Externality and Human Evolution’’ to ‘‘Radiator Theory of Brain’’: a Very Short Review","authors":"G. Iurato","doi":"10.31579/2578-8868/205","DOIUrl":"https://doi.org/10.31579/2578-8868/205","url":null,"abstract":"This review of the paper ‘‘Entropy, externality and human evolution’’ by G. Iurato and A.Yu. Khrennikov, for the Journal of Neuroscience and Neurological Surgery, is aimed to highlight the main neuroscience and paleo-neurology implications of the theoretical research conducted in such a work, above all in relation to the so-called Radiator Theory of evolution of the brain.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44156474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Both Mexico and United States share a border aswell as Mexico being the country with the most American citizens living abroad and United States housing millions of individuals of Mexican descent, Covid 19 has impacted the world and both countries health system Mexico having to deal with the impact of a pandemic with a much lower budget and personnel compared to United States and aswell United States having to deal with a pandemic occurring in a country with more 330,000,000 persons of all type of ethnicities United states has being the country with the most cases confirmed of covid 19 in the World in this article we will compare the first 6 months of covid 19 in Mexico as well as in the United States and current data for nowadays of Covid 19.
{"title":"Comparing Usa and Mexico Response to Covid as well as Incidence and Death toll for the First 6 Months from February 2020 to august 2020 and the Pandemic on June 1st 2021","authors":"G. Nava","doi":"10.31579/2578-8868/197","DOIUrl":"https://doi.org/10.31579/2578-8868/197","url":null,"abstract":"Both Mexico and United States share a border aswell as Mexico being the country with the most American citizens living abroad and United States housing millions of individuals of Mexican descent, Covid 19 has impacted the world and both countries health system Mexico having to deal with the impact of a pandemic with a much lower budget and personnel compared to United States and aswell United States having to deal with a pandemic occurring in a country with more 330,000,000 persons of all type of ethnicities United states has being the country with the most cases confirmed of covid 19 in the World in this article we will compare the first 6 months of covid 19 in Mexico as well as in the United States and current data for nowadays of Covid 19.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47989391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is a difference in prevalence of Epilepsy in General population & MS patients. Interical Epileptiform Discharges (IED) positivity in EEG is also different in the above two populations. Demyelination slows down the conduction speed of axons and author is proposing that different speed of conduction in adjacent axons can generate re-entrant circuits. If the reentrant circuits involve Corpus callosum (CC) fibers, seizure activities of MS can be triggered. DBS applied to CC can terminate the seizure attack of MS like Vagal Nerve Simulator (VNS) in terminating seizure in general population.
{"title":"Muliple Sclerosis, Corpus Callosum & Epilepsy","authors":"Khin Maung Bo","doi":"10.31579/2578-8868/199","DOIUrl":"https://doi.org/10.31579/2578-8868/199","url":null,"abstract":"There is a difference in prevalence of Epilepsy in General population & MS patients. Interical Epileptiform Discharges (IED) positivity in EEG is also different in the above two populations. Demyelination slows down the conduction speed of axons and author is proposing that different speed of conduction in adjacent axons can generate re-entrant circuits. If the reentrant circuits involve Corpus callosum (CC) fibers, seizure activities of MS can be triggered. DBS applied to CC can terminate the seizure attack of MS like Vagal Nerve Simulator (VNS) in terminating seizure in general population.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43846549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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