This work focuses on the study of neurobiological and functional profiles in terms of bisexuality, to carefully evaluate the direct correlation between anatomical and physiological elements and the choice of sexual preferences oriented on both sexes, hypothesizing any clinical profiles.
{"title":"Bisexuality: definition, humanistic profiles, neural correlates and clinical hypotheses","authors":"G. Perrotta","doi":"10.31579/2578-8868/138","DOIUrl":"https://doi.org/10.31579/2578-8868/138","url":null,"abstract":"This work focuses on the study of neurobiological and functional profiles in terms of bisexuality, to carefully evaluate the direct correlation between anatomical and physiological elements and the choice of sexual preferences oriented on both sexes, hypothesizing any clinical profiles.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70016752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recalling the concept of "epilepsy", already analyzed in a previous publication, this work focuses on the specific study of the best pharmacological treatments for the morbid condition under examination, paying attention to the clinical and prospective aspects of therapy, also in light of recent discoveries in the neuroinflammatory and neurogenetic field.
{"title":"The pharmacological treatment of epileptic seizures in children and adults: introduction, clinical contexts, psychopharmacological profiles and prospects in the neurogenetic field","authors":"G. Perrotta","doi":"10.31579/2578-8868/137","DOIUrl":"https://doi.org/10.31579/2578-8868/137","url":null,"abstract":"Recalling the concept of \"epilepsy\", already analyzed in a previous publication, this work focuses on the specific study of the best pharmacological treatments for the morbid condition under examination, paying attention to the clinical and prospective aspects of therapy, also in light of recent discoveries in the neuroinflammatory and neurogenetic field.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70017145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Though aging is a gift in general, it may be a hard time for many in developing countries in particular. Aging may be defined as the combination of biological, social and psychological processes that affect people as they grow older. The first refers to the physical body, the second refers to cultural values, norms and role expectations that change with age, and the third refers to the change in one's emotional, cognitive and mental capabilities. Science, modern technologies, improved agriculture, sanitation, medicaments, improved nutrition and many more developments have brought about aging increase and declining mortality. Social aspects of aging or social gerontology as a new phenomenon needs to be taken into account through social accounting. As rapid changes are emerging in population structure in modern times, social accountants need to study and project different emerging changes of population including aging and gerontology. While aging is affected by the quality of the society, it affects society too. Such a phenomenon is currently appearing in the developing world. Similarly, aging people find a different psychology and lifestyle contradicting their younger ages. Such a dramatic change needs more applicable inspection including geriatrics and social accounting. However, complications in elderly life is ever appearing and increasing. Method of research used in the present paper is mainly based on a qualitative approach. Various subtitles discussed in the present paper, result from aging, or influence aging phenomenon. The paper concludes that social accounting widely affects healthy aging.
{"title":"Aging and Social Gerontology vs Social Accounting in Developing Countries","authors":"M. Sheykhi","doi":"10.31579/2578-8868/105","DOIUrl":"https://doi.org/10.31579/2578-8868/105","url":null,"abstract":"Though aging is a gift in general, it may be a hard time for many in developing countries in particular. Aging may be defined as the combination of biological, social and psychological processes that affect people as they grow older. The first refers to the physical body, the second refers to cultural values, norms and role expectations that change with age, and the third refers to the change in one's emotional, cognitive and mental capabilities. Science, modern technologies, improved agriculture, sanitation, medicaments, improved nutrition and many more developments have brought about aging increase and declining mortality. Social aspects of aging or social gerontology as a new phenomenon needs to be taken into account through social accounting. As rapid changes are emerging in population structure in modern times, social accountants need to study and project different emerging changes of population including aging and gerontology. While aging is affected by the quality of the society, it affects society too. Such a phenomenon is currently appearing in the developing world. Similarly, aging people find a different psychology and lifestyle contradicting their younger ages. Such a dramatic change needs more applicable inspection including geriatrics and social accounting. However, complications in elderly life is ever appearing and increasing. Method of research used in the present paper is mainly based on a qualitative approach. Various subtitles discussed in the present paper, result from aging, or influence aging phenomenon. The paper concludes that social accounting widely affects healthy aging.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70016411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intraoperative Neurophysiological Monitoring evaluates nervous system responses during surgery and classifies data as normal or abnormal. However it has been difficult to standardize Intraoperative Neurophysiological Monitoring results and to link intraoperative data to post-surgical outcomes, with alert criteria and concepts that contrast through laboratories and guidelines. Clinical Randomized Trials have not been applied for investigation because of ethical issues, but still more investigation is needed. Neuroethics and Intraoperative Neurophysiological Monitoring are related because the latter encompass patient’s post-surgical outcome and life quality. In this paper investigation methods proposed for Intraoperative Neurophysiological Monitoring are reviewed with consequent opinions. Moreover a quasi-experimental design for investigation is proposed, which is closer to Neuroethics and patients wellbeing.
{"title":"The investigation of Intraoperative Neurophysiological Monitoring and its Relevance to Neuroethics","authors":"Raúl Roberto Valdés Sedeño","doi":"10.31579/2578-8868/116","DOIUrl":"https://doi.org/10.31579/2578-8868/116","url":null,"abstract":"Intraoperative Neurophysiological Monitoring evaluates nervous system responses during surgery and classifies data as normal or abnormal. However it has been difficult to standardize Intraoperative Neurophysiological Monitoring results and to link intraoperative data to post-surgical outcomes, with alert criteria and concepts that contrast through laboratories and guidelines. Clinical Randomized Trials have not been applied for investigation because of ethical issues, but still more investigation is needed. Neuroethics and Intraoperative Neurophysiological Monitoring are related because the latter encompass patient’s post-surgical outcome and life quality. In this paper investigation methods proposed for Intraoperative Neurophysiological Monitoring are reviewed with consequent opinions. Moreover a quasi-experimental design for investigation is proposed, which is closer to Neuroethics and patients wellbeing.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70016532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ehlers-Danlos syndrome (EDS) appears today to be very common but is still, paradoxically, considered as rare because of a very scarce and belated diagnosis. Respiratory manifestations (exertional dyspnea, painful inspiratory bradypnea and sleep apnea are among the poorly understood manifestations of this diffuse inherited collagen disease. They can cause diagnostic errors, especially with asthma, which can lead to worsening, in these patients with very fragile tissues (including bones), contraindicating corticosteroid therapy. EDS should be systematically discussed in case of respiratory disorders in children but also in adults. There are very beneficial effects observed with oxygen therapy which considerably helps with symptoms such as fatigue, migraine, cognition, by correcting cerebral anoxia which accompanies it. Pneumologists should be made aware of the benefits of oxygen therapy when faced with an EDS patient as they may have to prescribe it.
{"title":"Ehlers-Danlos and respiratory function. Clinical data on a cohort of 5,700 patients: oxygen therapy and physical rehabilitation medicine (P.R.M.)","authors":"Claude Hamone","doi":"10.31579/2578-8868/122","DOIUrl":"https://doi.org/10.31579/2578-8868/122","url":null,"abstract":"Ehlers-Danlos syndrome (EDS) appears today to be very common but is still, paradoxically, considered as rare because of a very scarce and belated diagnosis. Respiratory manifestations (exertional dyspnea, painful inspiratory bradypnea and sleep apnea are among the poorly understood manifestations of this diffuse inherited collagen disease. They can cause diagnostic errors, especially with asthma, which can lead to worsening, in these patients with very fragile tissues (including bones), contraindicating corticosteroid therapy. EDS should be systematically discussed in case of respiratory disorders in children but also in adults. There are very beneficial effects observed with oxygen therapy which considerably helps with symptoms such as fatigue, migraine, cognition, by correcting cerebral anoxia which accompanies it. Pneumologists should be made aware of the benefits of oxygen therapy when faced with an EDS patient as they may have to prescribe it.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70016649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary Epilepsy is one of the most frequent chronic neurological pathologies, with high incidence and prevalence worldwide. A third of these patients are resistant to treatment, which is known as refractory epilepsy. Most of these patients suffer epilepsy secondary to epileptogenic lesions, where the surgery is the only treatment that could cure epilepsy. The goal of epilepsy surgery is to remove the epileptogenic area with preservation of eloquent areas, and here the surgical experience, the neuroimaging technology and the availability of image-guided surgery systems known as a neuronavigator plays a key role. Objectives: To demonstrate the usefulness of neuronavigation in pre-surgical planning and in the surgery of refractory epilepsy. Method: A cross-sectional and analytical descriptive study was conducted based on 47 surgeries performed (12 resective, 32 palliative and 3 diagnostic) in patients with refractory epilepsy and mean age of 9.93 years (SD 4.1). In 27 patients (57.44%) the neuronavigator was used. In the group of patients operated with neuronavigation, the surgical time decreased by 47.17 minutes (p = 0.022), the amount of bleeding by 111.41 milliliters (p = 0.011) and the days of hospitalization by 6.68 days (p = 0.005), compared with the group operated without neuronavigation. Complications in the neuronavigation group were 29.63% compared to 65% in the group operated without neuronavigation (p = 0.034). Conclusions: In our series, the use of the neuronavigator in the planning and development of the surgery had a significant impact by reducing the amount of bleeding lost, the surgical time, the days of hospitalization, and the post-surgical complications.
癫痫是最常见的慢性神经系统疾病之一，在世界范围内具有很高的发病率和患病率。这些患者中有三分之一对治疗有抗药性，这被称为难治性癫痫。这些患者大多继发于癫痫病变，手术是唯一可以治愈癫痫的治疗方法。癫痫手术的目标是切除致痫区，同时保留有效区域，在这里，手术经验、神经成像技术和可用的图像引导手术系统(称为神经导航器)起着关键作用。目的:探讨神经导航技术在难治性癫痫术前规划及手术中的应用价值。方法:对平均年龄9.93岁(SD 4.1)的顽固性癫痫患者进行47例手术(切除12例，姑息32例，诊断3例)的横断面分析性描述性研究。27例(57.44%)患者使用神经导航仪。与未行神经导航组相比，行神经导航组手术时间减少47.17 min (p = 0.022)，出血量减少111.41 ml (p = 0.011)，住院天数减少6.68 d (p = 0.005)。神经导航组并发症发生率为29.63%，非神经导航组为65% (p = 0.034)。结论:在我们的系列研究中，神经导航仪在手术计划和发展中的应用通过减少出血量、手术时间、住院天数和术后并发症而产生了显著的影响。
{"title":"Neuronavigation as a Tool for Pre-Surgical Planning in Refractory Epilepsy Surgery","authors":"C. V. Calderón","doi":"10.31579/2578-8868/095","DOIUrl":"https://doi.org/10.31579/2578-8868/095","url":null,"abstract":"Summary Epilepsy is one of the most frequent chronic neurological pathologies, with high incidence and prevalence worldwide. A third of these patients are resistant to treatment, which is known as refractory epilepsy. Most of these patients suffer epilepsy secondary to epileptogenic lesions, where the surgery is the only treatment that could cure epilepsy. The goal of epilepsy surgery is to remove the epileptogenic area with preservation of eloquent areas, and here the surgical experience, the neuroimaging technology and the availability of image-guided surgery systems known as a neuronavigator plays a key role. Objectives: To demonstrate the usefulness of neuronavigation in pre-surgical planning and in the surgery of refractory epilepsy. Method: A cross-sectional and analytical descriptive study was conducted based on 47 surgeries performed (12 resective, 32 palliative and 3 diagnostic) in patients with refractory epilepsy and mean age of 9.93 years (SD 4.1). In 27 patients (57.44%) the neuronavigator was used. In the group of patients operated with neuronavigation, the surgical time decreased by 47.17 minutes (p = 0.022), the amount of bleeding by 111.41 milliliters (p = 0.011) and the days of hospitalization by 6.68 days (p = 0.005), compared with the group operated without neuronavigation. Complications in the neuronavigation group were 29.63% compared to 65% in the group operated without neuronavigation (p = 0.034). Conclusions: In our series, the use of the neuronavigator in the planning and development of the surgery had a significant impact by reducing the amount of bleeding lost, the surgical time, the days of hospitalization, and the post-surgical complications.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47550322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A thirty-one year-old Sri Lankan man presented with a two-month history of progressive pan-cerebellar syndrome, following allogeneic stem cell transplantation. This curative-intent therapy was performed in the context of an underlying acute myeloid leukemia. During the post-transplant period, patients are extremely vulnerable, especially due to the immunologic fluctuations. Reaching equilibrium is crucial, preventing complications of both extremes of the immunologic response, such as opportunistic infections or graft versus host disease. Numerous aetiologies were considered in the differential diagnosis of this pan-cerebellar syndrome. Most of those conditions mandate a prompt management, because of their reversible or lethal nature. Our thorough investigation process was a race against time. Excluding “Red Flags” remains the priority. Mindfulness and time will eventually lead to the proper diagnosis. We discuss our structured investigation process emphasizing on the key element: a “Systematic Approach”.
{"title":"Ataxia Following Allogenic Stem Cell Transplantation: No Stone Unturned","authors":"C. Maurice, Austin M. Pereira, Warren P. Mason","doi":"10.31579/2578-8868/108","DOIUrl":"https://doi.org/10.31579/2578-8868/108","url":null,"abstract":"A thirty-one year-old Sri Lankan man presented with a two-month history of progressive pan-cerebellar syndrome, following allogeneic stem cell transplantation. This curative-intent therapy was performed in the context of an underlying acute myeloid leukemia. During the post-transplant period, patients are extremely vulnerable, especially due to the immunologic fluctuations. Reaching equilibrium is crucial, preventing complications of both extremes of the immunologic response, such as opportunistic infections or graft versus host disease. Numerous aetiologies were considered in the differential diagnosis of this pan-cerebellar syndrome. Most of those conditions mandate a prompt management, because of their reversible or lethal nature. Our thorough investigation process was a race against time. Excluding “Red Flags” remains the priority. Mindfulness and time will eventually lead to the proper diagnosis. We discuss our structured investigation process emphasizing on the key element: a “Systematic Approach”.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44952837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saint Hildegard’s and Viktor Frankl’s healing methods and Split Brain Research inspired by Hildegard, Gerty Spies, Leibniz, Kant, Goethe, Schiller, Humboldt, Binnig & Co.
{"title":"Healing Noble Brains and Nobel Laureates as Peacemakers","authors":"Konrad Frischeisen","doi":"10.31579/2578-8868/110","DOIUrl":"https://doi.org/10.31579/2578-8868/110","url":null,"abstract":"Saint Hildegard’s and Viktor Frankl’s healing methods and Split Brain Research inspired by Hildegard, Gerty Spies, Leibniz, Kant, Goethe, Schiller, Humboldt, Binnig & Co.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47979001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the journey of science and scientific discoveries, many scientific theories and hypotheses developed by scientists received acceptance and became famous in the past, but now, science proved them wrong1. To the point of wondering, one asks himself, how these theories went, and how scientists have accepted their interpretation at that time to be rejected now?.
{"title":"Why the wrong Scientific Theories are not Corrected and Re-evaluated again by Scientists","authors":"Othman Salim Hussein Al-Fleesy","doi":"10.31579/2578-8868/099","DOIUrl":"https://doi.org/10.31579/2578-8868/099","url":null,"abstract":"In the journey of science and scientific discoveries, many scientific theories and hypotheses developed by scientists received acceptance and became famous in the past, but now, science proved them wrong1. To the point of wondering, one asks himself, how these theories went, and how scientists have accepted their interpretation at that time to be rejected now?.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42187423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Study nature of epidemiological risk factors and patterns of distribution of mortality from Alzheimer's (MA) in 160 countries. An exponential Malthus model was used to construct adequate approximations of statistical data. Proportionality of average lifetime after 55 years (Δt) to education index (Ψ) was established. Ranking of countries by increasing value of ΨΔt showed that MA depends exponentially on ΨΔt and all countries can be divided into three groups in accordance with level of their economic development. In series of countries of low, medium and highly developed, their average values of MA increase exponentially. Growth of MA in developed countries in post-industrial epoch was explained by emergence of a new risk factor Alzheimer's of a mental nature. A mismatch of complexity or, on contrary, primitiveness of profession with level of mental development of worker, provokes development of chronic stress in him, fraught with pathologies of cognitive function metabolism in elderly. The geography of Alzheimer's disease was explained by the dependence of the human mentality on latitudinal climate change and on the chiral factor of a solar nature acting at night on a sleeping person.
{"title":"The Geography and Demographics of Mortality from Alzheimer's disease","authors":"A. Kholmanskiy","doi":"10.31579/2578-8868/101","DOIUrl":"https://doi.org/10.31579/2578-8868/101","url":null,"abstract":"Study nature of epidemiological risk factors and patterns of distribution of mortality from Alzheimer's (MA) in 160 countries. An exponential Malthus model was used to construct adequate approximations of statistical data. Proportionality of average lifetime after 55 years (Δt) to education index (Ψ) was established. Ranking of countries by increasing value of ΨΔt showed that MA depends exponentially on ΨΔt and all countries can be divided into three groups in accordance with level of their economic development. In series of countries of low, medium and highly developed, their average values of MA increase exponentially. Growth of MA in developed countries in post-industrial epoch was explained by emergence of a new risk factor Alzheimer's of a mental nature. A mismatch of complexity or, on contrary, primitiveness of profession with level of mental development of worker, provokes development of chronic stress in him, fraught with pathologies of cognitive function metabolism in elderly. The geography of Alzheimer's disease was explained by the dependence of the human mentality on latitudinal climate change and on the chiral factor of a solar nature acting at night on a sleeping person.","PeriodicalId":73865,"journal":{"name":"Journal of neuroscience and neurological surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46694295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：