Pub Date : 2017-08-31DOI: 10.4172/2167-0277.1000276
Lílian Kcr, K. Cristiane, Branca Dbs, Marco Tm, Virgínia Fmt
Despite the small number of studies about sleep quality and its possible occurrence in SLE, it is a frequent complaint among patients. This study evaluated sleep quality using actigraphy and the Pittsburgh sleep quality index (PSQI) in 46 women with SLE and the relationship between disease activity, cumulative damage, quality of life, pain intensity, fatigue, and medication to treat the disease, as well as the influence of pain intensity (subgroups) on quality of life. The short-form 36 health survey (SF-36) assessed health related quality of life (HRQoL), the fatigue severity scale (FSS) assessed fatigue, and the visual analog scale (VAS) was used to evaluate pain intensity. The significance level was 5%. Objective and subjective measures were concordant in sleep latency. Univariate logistic regression analysis was performed using categorized VAS pain as a dependent variable, we found an association with sleep latency (actigraphy), PSQI global score, six components of the SF-36 (physical functioning, role physical or role limitations due to physical problems, bodily pain, vitality, social functioning, role emotional or role limitations due to emotional problems), and fatigue. In the final analyses, using multivariate logistic regression, the model showed that the predicting variables for HPG (high pain group) and LPG (low pain group) were sleep latency and fatigue. Perhaps we did not find associations between sleep and quality of life as other factors were more relevant, such as pain and fatigue.
{"title":"Evaluation of Sleep Quality by Actigraphy in Women with Systemic Lupus Erythematosus (SLE)","authors":"Lílian Kcr, K. Cristiane, Branca Dbs, Marco Tm, Virgínia Fmt","doi":"10.4172/2167-0277.1000276","DOIUrl":"https://doi.org/10.4172/2167-0277.1000276","url":null,"abstract":"Despite the small number of studies about sleep quality and its possible occurrence in SLE, it is a frequent complaint among patients. This study evaluated sleep quality using actigraphy and the Pittsburgh sleep quality index (PSQI) in 46 women with SLE and the relationship between disease activity, cumulative damage, quality of life, pain intensity, fatigue, and medication to treat the disease, as well as the influence of pain intensity (subgroups) on quality of life. The short-form 36 health survey (SF-36) assessed health related quality of life (HRQoL), the fatigue severity scale (FSS) assessed fatigue, and the visual analog scale (VAS) was used to evaluate pain intensity. The significance level was 5%. Objective and subjective measures were concordant in sleep latency. Univariate logistic regression analysis was performed using categorized VAS pain as a dependent variable, we found an association with sleep latency (actigraphy), PSQI global score, six components of the SF-36 (physical functioning, role physical or role limitations due to physical problems, bodily pain, vitality, social functioning, role emotional or role limitations due to emotional problems), and fatigue. In the final analyses, using multivariate logistic regression, the model showed that the predicting variables for HPG (high pain group) and LPG (low pain group) were sleep latency and fatigue. Perhaps we did not find associations between sleep and quality of life as other factors were more relevant, such as pain and fatigue.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":"6 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41408870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-03DOI: 10.4172/2167-0277.1000261
Y. Park, S. Choi, E. Joo
Objectives: Although rapid eye movement behavior disorder (RBD) and obstructive sleep apnea syndrome (OSA) have different pathophysiology, RBD patients with OSA appeared to have more stable sleep compared to patients with OSA and to verify it by cardiopulmonary coupling (CPC) method. Methods: The polysomnography (PSG) data of 138 subjects with OSA (AHI ≥ 15), RBD with OSA (AHI ≥ 15), RBD, normal control (N=32, 26, 29, 51, respectively) were collected. For conducting case control study between RBD with OSA and patients with OSA only, a total of 32 OSA controls, matched for age, AHI and BMI were recruited. CPC parameters were obtained using CPC analyzer in Rem Logic. Sleep spectrogram by CPC analyses revealed the percentage of stable tidal volume [high-frequency coupling (HFC), 0.1–0.4 Hz] and fluctuation tidal volume [lowfrequency coupling (LFC), 0.01 Hz to 0.1 Hz)] during sleep. Results: Although there was no significant Apnea-Hypopnea index (AHI) difference between RBD with OSA and OSA group (AHI 29.1 ± 15.6/hr vs. 34.1 ± 18.9, p=0.332), there was significant difference in CPC measurements. In RBD-OSA group showed lower LFC (35.9 ± 16.8 vs. 49.7 ± 21.3, p=0.010) than OSA group. Unlike higher AHI in RBD with OSA than RBD group (29.1 ± 15.6/hr vs. 3.2 ± 1.6, p<0.001), there was no significant difference in CPC study. Both OSA group and RBD with OSA group showed higher LFC (OSA vs. normal: 49.7 ± 21.3 vs. 28.4 ± 13.3, p<0.001, RBD with OSA vs. normal: 35.9 ± 16.8 vs. 28.4 ± 13.2 p=0.035) and lower HFC (OSA vs. normal: 37.5 ± 20.0 vs. 56.2 ± 16.2, p<0.001, RBD with OSA vs. normal: 46.8 ± 20.8 vs. 56.2 ± 16.2, p=0.031) when compared with normal control group, respectively. Conclusions: In terms of autonomic-respiratory interaction, RBD with OSA showed similar CPC profile (higher LFC and lower HFC than normal) to OSA group but less severe than pure OSA group. It suggests that RBD may have a protective effect on OSA.
{"title":"Electrophysiological Difference in Obstructive Sleep Apnea with and without REM sleep Behavior Disorder: Cardiopulmonary Coupling Analysis","authors":"Y. Park, S. Choi, E. Joo","doi":"10.4172/2167-0277.1000261","DOIUrl":"https://doi.org/10.4172/2167-0277.1000261","url":null,"abstract":"Objectives: Although rapid eye movement behavior disorder (RBD) and obstructive sleep apnea syndrome (OSA) have different pathophysiology, RBD patients with OSA appeared to have more stable sleep compared to patients with OSA and to verify it by cardiopulmonary coupling (CPC) method. \u0000Methods: The polysomnography (PSG) data of 138 subjects with OSA (AHI ≥ 15), RBD with OSA (AHI ≥ 15), RBD, normal control (N=32, 26, 29, 51, respectively) were collected. For conducting case control study between RBD with OSA and patients with OSA only, a total of 32 OSA controls, matched for age, AHI and BMI were recruited. CPC parameters were obtained using CPC analyzer in Rem Logic. Sleep spectrogram by CPC analyses revealed the percentage of stable tidal volume [high-frequency coupling (HFC), 0.1–0.4 Hz] and fluctuation tidal volume [lowfrequency coupling (LFC), 0.01 Hz to 0.1 Hz)] during sleep. \u0000Results: Although there was no significant Apnea-Hypopnea index (AHI) difference between RBD with OSA and OSA group (AHI 29.1 ± 15.6/hr vs. 34.1 ± 18.9, p=0.332), there was significant difference in CPC measurements. In RBD-OSA group showed lower LFC (35.9 ± 16.8 vs. 49.7 ± 21.3, p=0.010) than OSA group. Unlike higher AHI in RBD with OSA than RBD group (29.1 ± 15.6/hr vs. 3.2 ± 1.6, p<0.001), there was no significant difference in CPC study. Both OSA group and RBD with OSA group showed higher LFC (OSA vs. normal: 49.7 ± 21.3 vs. 28.4 ± 13.3, p<0.001, RBD with OSA vs. normal: 35.9 ± 16.8 vs. 28.4 ± 13.2 p=0.035) and lower HFC (OSA vs. normal: 37.5 ± 20.0 vs. 56.2 ± 16.2, p<0.001, RBD with OSA vs. normal: 46.8 ± 20.8 vs. 56.2 ± 16.2, p=0.031) when compared with normal control group, respectively. \u0000Conclusions: In terms of autonomic-respiratory interaction, RBD with OSA showed similar CPC profile (higher LFC and lower HFC than normal) to OSA group but less severe than pure OSA group. It suggests that RBD may have a protective effect on OSA.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":" ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0277.1000261","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48669385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-30DOI: 10.4172/2167-0277.1000275
K. Karatas, M. Bilici, Z. Pelin
Objective: Parasomnias are Sleep Disorders characterized by abnormal behavioral and physiological events. Dissociative experiences that occur in dissociative Disorders can emerge at night and may be the cause of parasomnia. The aim of this study is to compare the Sleep characteristics of parasomnia patients with and without dissociative disorder in order to investigate whether dissociative experiences may continue while aSleep and to what extent they change parasomnia. Method: Of patients who were evaluated after admission to the Center of Sleep Disorders (n: 2217) and polysomnography patients (n: 822), the study was conducted with 36 patients diagnosed with parasomnia according to the International Clasification of Sleep Disorder-2 diagnostic criteria. To patients diagnosed with parasomnia were evaluated with psychometric tests such as Dissociative Experiences Scale, Childhood Trauma Questionnaire, Pittsburg Sleep Quality Index, Iowa Sleep Experiences Survey, Hamilton Depression Rating Scale, Beck Depression Inventory, and Structured Clinical Interview for Dissociative Disorders. The patient group with parasomnia and dissociative disorder was called group I, and the patient group with parasomnia alone was called group II. Results: Dissociative disorder was detected in 41.6% of patients with parasomnia. The difference in psychometric test scores between Group I and Group II was statistically significant. In polysomnographic examination, all subjects in Group I and Group II were superficial with Sleep delta wave. Conclusion: Dissociative experiences and childhood trauma are more common in people with Parasomnia conditions. Patients with Parasomnia and Dissociative Disorder are more depressed, according to both the clinician’s and their own views on the subject. Delta slow wave bursts are similar in both groups.
{"title":"Parasomnia and Dissociative Disorders","authors":"K. Karatas, M. Bilici, Z. Pelin","doi":"10.4172/2167-0277.1000275","DOIUrl":"https://doi.org/10.4172/2167-0277.1000275","url":null,"abstract":"Objective: Parasomnias are Sleep Disorders characterized by abnormal behavioral and physiological events. Dissociative experiences that occur in dissociative Disorders can emerge at night and may be the cause of parasomnia. The aim of this study is to compare the Sleep characteristics of parasomnia patients with and without dissociative disorder in order to investigate whether dissociative experiences may continue while aSleep and to what extent they change parasomnia. Method: Of patients who were evaluated after admission to the Center of Sleep Disorders (n: 2217) and polysomnography patients (n: 822), the study was conducted with 36 patients diagnosed with parasomnia according to the International Clasification of Sleep Disorder-2 diagnostic criteria. To patients diagnosed with parasomnia were evaluated with psychometric tests such as Dissociative Experiences Scale, Childhood Trauma Questionnaire, Pittsburg Sleep Quality Index, Iowa Sleep Experiences Survey, Hamilton Depression Rating Scale, Beck Depression Inventory, and Structured Clinical Interview for Dissociative Disorders. The patient group with parasomnia and dissociative disorder was called group I, and the patient group with parasomnia alone was called group II. Results: Dissociative disorder was detected in 41.6% of patients with parasomnia. The difference in psychometric test scores between Group I and Group II was statistically significant. In polysomnographic examination, all subjects in Group I and Group II were superficial with Sleep delta wave. Conclusion: Dissociative experiences and childhood trauma are more common in people with Parasomnia conditions. Patients with Parasomnia and Dissociative Disorder are more depressed, according to both the clinician’s and their own views on the subject. Delta slow wave bursts are similar in both groups.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":"6 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0277.1000275","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43254651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-23DOI: 10.4172/2167-0277.1000273
F. GholamiDamian, J. MahmoodiGharaie, P. Sabzali, F. Darabi, P. Hajiseyedjavadi
Objectives: Some studies reported a significant improvement in sleep parameters by melatonin therapy in children with ADHD. Utilizing risperidone along with stimulants is another pharmacologic approach for ADHD treatment. In this study we investigated the effect of melatonin and risperidone on sleep disorders in children with ADHD and compared their effectiveness as well. Methods & Methods: 29 patient aged 6 years to 12 years old with ADHD were randomly divided into two groups based on file number: either received melatonin (3 mg to 6 mg) combined with Ritalin or received risperidone (0.25mg to 0.5 mg) combined with Ritalin in a single blind randomized clinical trial. Assessments were performed at baseline and were repeated at 2 and 4 weeks after beginning of the treatment. Results: In risperidone group significant differences has been found in total score of sleep disorders (P=0.000), sleep onset and maintenance score (P=0.000), Sleep-wake transition disorders (P=0.000), but no significant differences in breathing (P=0.104), and hyperhidrosis (P=0.105) and excessive daytime sleepiness score (p=0.065), and in arousal group after 2 weeks (p=0.027) and after 4 weeks (p=0.150). comparison of melatonin group in different weeks (Base line with 2 and 4 weeks after treatment), show significant differences in total score of sleep disorders (P=0.000), sleep onset and maintenance score (P=0.000), Sleep-wake transition disorders (P=0.003), excessive daytime sleepiness (P=0.004), but no significant differences in breathing (P=0.068) and arousal (P=0.218) and hyperhydrosis score (P=0.336). Conclusion: The results showed the equal effect of risperidone and melatonin. It can be concluded that the risperidone has the same effect of melatonin in the treatment of sleep disorders in children with ADHD.
{"title":"Comparison of Risperidone and Melatonin Effects in Methylphenidate Treated Children with Attention Deficit Hyperactivity Disorder for Treatment of Sleep Disorders","authors":"F. GholamiDamian, J. MahmoodiGharaie, P. Sabzali, F. Darabi, P. Hajiseyedjavadi","doi":"10.4172/2167-0277.1000273","DOIUrl":"https://doi.org/10.4172/2167-0277.1000273","url":null,"abstract":"Objectives: Some studies reported a significant improvement in sleep parameters by melatonin therapy in children with ADHD. Utilizing risperidone along with stimulants is another pharmacologic approach for ADHD treatment. In this study we investigated the effect of melatonin and risperidone on sleep disorders in children with ADHD and compared their effectiveness as well. \u0000Methods & Methods: 29 patient aged 6 years to 12 years old with ADHD were randomly divided into two groups based on file number: either received melatonin (3 mg to 6 mg) combined with Ritalin or received risperidone (0.25mg to 0.5 mg) combined with Ritalin in a single blind randomized clinical trial. Assessments were performed at baseline and were repeated at 2 and 4 weeks after beginning of the treatment. \u0000Results: In risperidone group significant differences has been found in total score of sleep disorders (P=0.000), sleep onset and maintenance score (P=0.000), Sleep-wake transition disorders (P=0.000), but no significant differences in breathing (P=0.104), and hyperhidrosis (P=0.105) and excessive daytime sleepiness score (p=0.065), and in arousal group after 2 weeks (p=0.027) and after 4 weeks (p=0.150). comparison of melatonin group in different weeks (Base line with 2 and 4 weeks after treatment), show significant differences in total score of sleep disorders (P=0.000), sleep onset and maintenance score (P=0.000), Sleep-wake transition disorders (P=0.003), excessive daytime sleepiness (P=0.004), but no significant differences in breathing (P=0.068) and arousal (P=0.218) and hyperhydrosis score (P=0.336). \u0000Conclusion: The results showed the equal effect of risperidone and melatonin. It can be concluded that the risperidone has the same effect of melatonin in the treatment of sleep disorders in children with ADHD.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42847576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.4172/2167-0277.1000274
P. Dutta, S. West
A 47-year-old woman presented to clinic with exertional breathlessness, snoring, choking, witnessed apnoeas and daytime somnolence. Past history included Idiopathic Juvenile Arthritis, diagnosed at age 8, since when she had been taking prednisolone. Her sleep study identified severe Obstructive Sleep Apnoea (OSA). She was commenced on Continuous Positive Airway Pressure (CPAP) therapy, which improved her sleep quality so much that she hardly moved at night and consequently woke up with early morning joint stiffness. She therefore limited her CPAP use and her symptoms persisted. Over time she developed a regime of split-night CPAP use that improved her OSA-related symptoms and joint discomfort.
{"title":"Split-Night CPAP Therapy for OSA to Improve Joint Immobility","authors":"P. Dutta, S. West","doi":"10.4172/2167-0277.1000274","DOIUrl":"https://doi.org/10.4172/2167-0277.1000274","url":null,"abstract":"A 47-year-old woman presented to clinic with exertional breathlessness, snoring, choking, witnessed apnoeas and daytime somnolence. Past history included Idiopathic Juvenile Arthritis, diagnosed at age 8, since when she had been taking prednisolone. Her sleep study identified severe Obstructive Sleep Apnoea (OSA). \u0000She was commenced on Continuous Positive Airway Pressure (CPAP) therapy, which improved her sleep quality so much that she hardly moved at night and consequently woke up with early morning joint stiffness. She therefore limited her CPAP use and her symptoms persisted. Over time she developed a regime of split-night CPAP use that improved her OSA-related symptoms and joint discomfort.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":"2017 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44288518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-29DOI: 10.4172/2167-0277.1000E141
K. Radek
Sleep hygiene is a collection of prescribed behaviors to reduce activation at presleep. In early investigations of sleep quality, researchers identified educative directives that when given to poor sleepers resulted in some benefit in sleep onset latency and total sleep time. From this, professional sleep specialists’ interventions to self-help sleep health information included this list.
{"title":"New considerations for Sleep Hygiene","authors":"K. Radek","doi":"10.4172/2167-0277.1000E141","DOIUrl":"https://doi.org/10.4172/2167-0277.1000E141","url":null,"abstract":"Sleep hygiene is a collection of prescribed behaviors to reduce activation at presleep. In early investigations of sleep quality, researchers identified educative directives that when given to poor sleepers resulted in some benefit in sleep onset latency and total sleep time. From this, professional sleep specialists’ interventions to self-help sleep health information included this list.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":" ","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2017-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0277.1000E141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48783793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-21DOI: 10.4172/2167-0277.1000272
Amoric M
Sleep apnea and obstructive sleep disorders represent a danger for the cardiovascular system and metabolism. They also give rise to somnolence, which can cause accidents at work or road accidents. Along with positive pressure ventilation, oral mandibular advancement devices are today regarded as reliable forms of treatment. Unfortunately, not all patients adhere fully to the treatment, particularly over time. Some even abandon it entirely. The reasons generally put forward to explain this poor compliance are discomfort, pain, occlusal problems and poor psychological disposition (Figure 1). Orthesis over three years showing the high levels during the first months of treatment.
{"title":"Treatment of Sleep Apnea with Herbst Mandibular Advancement Splints","authors":"Amoric M","doi":"10.4172/2167-0277.1000272","DOIUrl":"https://doi.org/10.4172/2167-0277.1000272","url":null,"abstract":"Sleep apnea and obstructive sleep disorders represent a danger for the cardiovascular system and metabolism. They also give rise to somnolence, which can cause accidents at work or road accidents. Along with positive pressure ventilation, oral mandibular advancement devices are today regarded as reliable forms of treatment. Unfortunately, not all patients adhere fully to the treatment, particularly over time. Some even abandon it entirely. The reasons generally put forward to explain this poor compliance are discomfort, pain, occlusal problems and poor psychological disposition (Figure 1). Orthesis over three years showing the high levels during the first months of treatment.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":" ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49482181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-16DOI: 10.4172/2167-0277.1000271
Y. Yamaguchi, Masako Kato
Background: Although the continuous positive airway pressure is the gold standard therapy for patients with moderate to severe obstructive sleep apnea-hypopnea syndrome (OSAHS), there are several treatment options such as mandibular advancement devices, tongue-retaining devices, and nasal airway stent devices. Recently, newly developed intraoral pressure gradient therapy system, iNAP® Sleep Therapy System, was introduced as an alternative treatment for OSAHS patients. Purpose: This feasibility study explored the effectiveness of the iNAP® device for patients with mild to moderate OSAHS. Materials and Methods: The iNAP® device consisted of an oral interface, a tube set with a saliva container, and a negative pressure console. Negative pressure is introduced directly from the oral interface and the pressure pulls the tongue anteriorly, resulting in improving the obstruction or narrowing of the upper airway. A total of 5 male and 4 female patients with mild to moderate OSAHS, aged between 32 and 62, with 50.6 years ± 11.7 years were recruited in the study. Results: The baseline apnea-hypopnea index (AHI) was 17.2 events per hour ± 4.7 events per hour, while AHI with the iNAP® device was 12.7 ± 5.4 (p<0.01). Regarding the sleep architecture, a significant reduction in wakefulness after sleep onset (WASO) on the initial night of treatment from 97 min ± 50.0 min to 70.7 min ± 36.9 min (p<0.05) was observed; however, other sleep parameters were not. Conclusion: This study demonstrated that negative pressure therapy with the iNAP® device improved the apnea severity in patients with mild to moderate OSAHS, the degree of whose amelioration of AHI was marginal but significant. Although the number of patients recruited was small, this study is the first report on the effectiveness of the intraoral pressure gradient therapy.
{"title":"Pilot Study of Oral Negative Pressure Therapy for Obstructive Sleep Apnea-Hypopnea Syndrome","authors":"Y. Yamaguchi, Masako Kato","doi":"10.4172/2167-0277.1000271","DOIUrl":"https://doi.org/10.4172/2167-0277.1000271","url":null,"abstract":"Background: Although the continuous positive airway pressure is the gold standard therapy for patients with moderate to severe obstructive sleep apnea-hypopnea syndrome (OSAHS), there are several treatment options such as mandibular advancement devices, tongue-retaining devices, and nasal airway stent devices. Recently, newly developed intraoral pressure gradient therapy system, iNAP® Sleep Therapy System, was introduced as an alternative treatment for OSAHS patients. Purpose: This feasibility study explored the effectiveness of the iNAP® device for patients with mild to moderate OSAHS. Materials and Methods: The iNAP® device consisted of an oral interface, a tube set with a saliva container, and a negative pressure console. Negative pressure is introduced directly from the oral interface and the pressure pulls the tongue anteriorly, resulting in improving the obstruction or narrowing of the upper airway. A total of 5 male and 4 female patients with mild to moderate OSAHS, aged between 32 and 62, with 50.6 years ± 11.7 years were recruited in the study. Results: The baseline apnea-hypopnea index (AHI) was 17.2 events per hour ± 4.7 events per hour, while AHI with the iNAP® device was 12.7 ± 5.4 (p<0.01). Regarding the sleep architecture, a significant reduction in wakefulness after sleep onset (WASO) on the initial night of treatment from 97 min ± 50.0 min to 70.7 min ± 36.9 min (p<0.05) was observed; however, other sleep parameters were not. Conclusion: This study demonstrated that negative pressure therapy with the iNAP® device improved the apnea severity in patients with mild to moderate OSAHS, the degree of whose amelioration of AHI was marginal but significant. Although the number of patients recruited was small, this study is the first report on the effectiveness of the intraoral pressure gradient therapy.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0277.1000271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45497712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-11DOI: 10.4172/2167-0277.1000270
K. Hosokawa, Tsuguo Nishijima, T. Kizawa, F. Endo, S. Sakurai
Excessive daytime sleepiness (EDS) is observed in various pathological conditions associated with sleep disorders. However, objective methods for the assessment of EDS rely on complex electroencephalographic (EEG) recording and are impractical for use in general clinical practice. To address this issue, the Oxford Sleep Resistance Test (OSLER) has been developed for use in clinical practice overseas, though few studies have examined the reliability of the OSLER test for measuring sleep latency in Japanese patients. Thus, in the present study, we aimed to determine whether sleep latency measured via the OSLER test (SLOSLER) is consistent with that measured via EEG (SLEEG) in Japanese patients with obstructive sleep apnea (OSA). Seventeen Japanese men with OSA (mean age: 51.5 ± 9.8 years) underwent simultaneous OSLER and EEG testing a total of four times on the day following polysomnography evaluation. SLOSLER and SLEEG were compared, and the reliability of the former was analysed using Bland-Altman plots. Mean SLOSLER and SLEEG for all patients were 26.9 ± 11.6 and 25.7 ± 12.2 minutes, respectively. A significant positive correlation was observed between these measurements (p<0.0001, r=0.963). Moreover, the Epworth Sleepiness Scale (ESS) scores were not significantly correlated with either SLOSLER or SLEEG. Bland-Altman plot analysis revealed that 94% of the plotted SLOSLER or SLEEG measurements converged within a range of mean ± 1.96 SD. Our findings thus demonstrated that SLOSLER is consistent with SLEEG in Japanese patients with OSA.
{"title":"Comparison of Sleep Latency Measured by the Oxford Sleep Resistance Test and Simultaneous EEG in Japanese Patients","authors":"K. Hosokawa, Tsuguo Nishijima, T. Kizawa, F. Endo, S. Sakurai","doi":"10.4172/2167-0277.1000270","DOIUrl":"https://doi.org/10.4172/2167-0277.1000270","url":null,"abstract":"Excessive daytime sleepiness (EDS) is observed in various pathological conditions associated with sleep disorders. However, objective methods for the assessment of EDS rely on complex electroencephalographic (EEG) recording and are impractical for use in general clinical practice. To address this issue, the Oxford Sleep Resistance Test (OSLER) has been developed for use in clinical practice overseas, though few studies have examined the reliability of the OSLER test for measuring sleep latency in Japanese patients. Thus, in the present study, we aimed to determine whether sleep latency measured via the OSLER test (SLOSLER) is consistent with that measured via EEG (SLEEG) in Japanese patients with obstructive sleep apnea (OSA). Seventeen Japanese men with OSA (mean age: 51.5 ± 9.8 years) underwent simultaneous OSLER and EEG testing a total of four times on the day following polysomnography evaluation. SLOSLER and SLEEG were compared, and the reliability of the former was analysed using Bland-Altman plots. Mean SLOSLER and SLEEG for all patients were 26.9 ± 11.6 and 25.7 ± 12.2 minutes, respectively. A significant positive correlation was observed between these measurements (p<0.0001, r=0.963). Moreover, the Epworth Sleepiness Scale (ESS) scores were not significantly correlated with either SLOSLER or SLEEG. Bland-Altman plot analysis revealed that 94% of the plotted SLOSLER or SLEEG measurements converged within a range of mean ± 1.96 SD. Our findings thus demonstrated that SLOSLER is consistent with SLEEG in Japanese patients with OSA.","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41582035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-01Epub Date: 2017-05-20DOI: 10.4172/2167-0277.1000269
Natasha J Williams, Girardin Jean-Louis, Mirnova E Ceïde, Abishek Pandey, Ricardo Osorio, Mary Mittelman, Samy I McFarlane
This study compared differences in both maladaptive beliefs and attitudes about sleep between African American (heareafter referred to as black) men at risk for obstructive sleep apnea (OSA) and those without OSA risk.
Methods: A convenience sample of 120 community-dwelling men provided sociodemographic, health and sleep data. A validated questionnaire was used to identify men at high risk for OSA and the Dysfunctional Beliefs and Attitudes about Sleep (DBAS-16) scale was used to measure endorsed attitudes and beliefs about sleep.
Results: The mean age of the sample was 42 ± 15 years. Men reported difficulty falling asleep (23%), difficulty maintaining sleep (23%), early morning awakening (35%), and use of sleep medicine (6%). 27% were at high risk for OSA. Men at high OSA risk had greater DBAS scores [F1, 92=13.68, p<0.001]; OSA risk was related to greater rate of sleep dissatisfaction overall [46% vs. 13%, Χ2=24.52, p<0.001].
Conclusion: The findings suggest that maladaptive beliefs and attitudes about sleep are important characteristics of black men at risk for OSA, and potential screenings around sleep difficulties should also consider these factors.
{"title":"Effect of Maladaptive Beliefs and Attitudes about Sleep among Community-dwelling African American Men at Risk for Obstructive Sleep Apnea.","authors":"Natasha J Williams, Girardin Jean-Louis, Mirnova E Ceïde, Abishek Pandey, Ricardo Osorio, Mary Mittelman, Samy I McFarlane","doi":"10.4172/2167-0277.1000269","DOIUrl":"https://doi.org/10.4172/2167-0277.1000269","url":null,"abstract":"<p><p>This study compared differences in both maladaptive beliefs and attitudes about sleep between African American (heareafter referred to as black) men at risk for obstructive sleep apnea (OSA) and those without OSA risk.</p><p><strong>Methods: </strong>A convenience sample of 120 community-dwelling men provided sociodemographic, health and sleep data. A validated questionnaire was used to identify men at high risk for OSA and the Dysfunctional Beliefs and Attitudes about Sleep (DBAS-16) scale was used to measure endorsed attitudes and beliefs about sleep.</p><p><strong>Results: </strong>The mean age of the sample was 42 ± 15 years. Men reported difficulty falling asleep (23%), difficulty maintaining sleep (23%), early morning awakening (35%), and use of sleep medicine (6%). 27% were at high risk for OSA. Men at high OSA risk had greater DBAS scores [F1, 92=13.68, p<0.001]; OSA risk was related to greater rate of sleep dissatisfaction overall [46% <i>vs</i>. 13%, Χ2=24.52, p<0.001].</p><p><strong>Conclusion: </strong>The findings suggest that maladaptive beliefs and attitudes about sleep are important characteristics of black men at risk for OSA, and potential screenings around sleep difficulties should also consider these factors.</p>","PeriodicalId":73946,"journal":{"name":"Journal of sleep disorders & therapy","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0277.1000269","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35348953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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