Keyonna M. King, Tatiana Tchouankam, Heidi Keeler, C. Minter, K. Love, Maria Teel-Williams, Grace Y Cai, P. Estabrooks
{"title":"Conceptualization and utilization of community engagement approaches in translational research: A scoping review","authors":"Keyonna M. King, Tatiana Tchouankam, Heidi Keeler, C. Minter, K. Love, Maria Teel-Williams, Grace Y Cai, P. Estabrooks","doi":"10.15761/jts.1000418","DOIUrl":"https://doi.org/10.15761/jts.1000418","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67492957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scott J. Denardo, A. Parish, Cynthia L. Green, Latasha Oxendine-Phillips, James E. Tcheng
{"title":"Antiplatelet therapy only, without anticoagulation, for percutaneous coronary intervention: A translational application of platelet slip","authors":"Scott J. Denardo, A. Parish, Cynthia L. Green, Latasha Oxendine-Phillips, James E. Tcheng","doi":"10.15761/jts.1000455","DOIUrl":"https://doi.org/10.15761/jts.1000455","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rubens Camargo Siqueira, Lilian Piron-Ruiz, Priscila Samara Saran, L. Castiglioni, Tainara Souza Pinho, Milton Artur Ruiz
{"title":"Improvement of the visual field after intravitreal use of bone marrow mononuclear fraction containing CD34 + stem cells in patients with retinitis pigmentosa: A case report","authors":"Rubens Camargo Siqueira, Lilian Piron-Ruiz, Priscila Samara Saran, L. Castiglioni, Tainara Souza Pinho, Milton Artur Ruiz","doi":"10.15761/jts.1000466","DOIUrl":"https://doi.org/10.15761/jts.1000466","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuhei Ugaji, Kumi Kimura, Yasuhiko Yamamoto, S. Munesue, Ai Harashima, T. Aikawa, Yasuhisa Yoshida, Tomonao Hamada, Toshifumi Hikichi, H. Matsubara, H. Tsuchiya
Diabetes mellitus is a metabolic disorder, and its prevalence is increasing worldwide. It is a major cause of cardiovascular disease, stroke, chronic kidney disease, neuropathy, blindness, and cancer, which are closely associated with morbidity and mortality in patients with diabetes. Diabetes has also been recognized to affect bone health in terms of bone strength, turnover, mineral density, and structure. Delayed bone healing is recognized as an additional complication of longstanding diabetes, which is associated with a high risk of delayed union, non-union, or pseudoarthrosis [1-3]. Prevention and improvement of the disabling bone complications in diabetes have attracted more attention.
{"title":"Pyridoxamine improves diabetes-evoked delayed bone repair in mice","authors":"Shuhei Ugaji, Kumi Kimura, Yasuhiko Yamamoto, S. Munesue, Ai Harashima, T. Aikawa, Yasuhisa Yoshida, Tomonao Hamada, Toshifumi Hikichi, H. Matsubara, H. Tsuchiya","doi":"10.15761/jts.1000413","DOIUrl":"https://doi.org/10.15761/jts.1000413","url":null,"abstract":"Diabetes mellitus is a metabolic disorder, and its prevalence is increasing worldwide. It is a major cause of cardiovascular disease, stroke, chronic kidney disease, neuropathy, blindness, and cancer, which are closely associated with morbidity and mortality in patients with diabetes. Diabetes has also been recognized to affect bone health in terms of bone strength, turnover, mineral density, and structure. Delayed bone healing is recognized as an additional complication of longstanding diabetes, which is associated with a high risk of delayed union, non-union, or pseudoarthrosis [1-3]. Prevention and improvement of the disabling bone complications in diabetes have attracted more attention.","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67492478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Locally advanced non-small-cell lung cancer (NSCLC): The potential role of concurrent immunotherapy and radiotherapy","authors":"M. M, Sgambato A, M. P, Spagnuolo A, Gridelli C","doi":"10.15761/jts.1000437","DOIUrl":"https://doi.org/10.15761/jts.1000437","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"370 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67493282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josh Tiller-Ormord, Ciera Korte, Robert D. Friedberg
{"title":"Helping pediatric patients tolerate uncertainty during unprecedented times: Translating findings from new research on developmental psychopathology and two promising measures","authors":"Josh Tiller-Ormord, Ciera Korte, Robert D. Friedberg","doi":"10.15761/jts.1000444","DOIUrl":"https://doi.org/10.15761/jts.1000444","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67496178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Boutsikou, Z. Iliodromiti, Abraham Pouliakis, Alma Soulai, Leoni Tzounakou, P. Volaki, Chrysoula Petropoulou, R. Sokou, N. Iacovidou
{"title":"Breastfeeding rates in the Covid-19 era: The experience of a Greek “Baby Friendly Hospital”","authors":"T. Boutsikou, Z. Iliodromiti, Abraham Pouliakis, Alma Soulai, Leoni Tzounakou, P. Volaki, Chrysoula Petropoulou, R. Sokou, N. Iacovidou","doi":"10.15761/jts.1000451","DOIUrl":"https://doi.org/10.15761/jts.1000451","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krepis P, Krepi A, Tsolia Mn, Iliodromiti Z, Boutsikou T, Iacovidou N, Soldatou A
{"title":"Infant safe sleep practices and adherence to the updated AAP recommendations","authors":"Krepis P, Krepi A, Tsolia Mn, Iliodromiti Z, Boutsikou T, Iacovidou N, Soldatou A","doi":"10.15761/jts.1000452","DOIUrl":"https://doi.org/10.15761/jts.1000452","url":null,"abstract":"","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In cancer drug discovery, 3D approaches have been implemented over the last years to model the complex tumor architecture and the heterogenous components of the tumor microenvironment. Cutaneous melanoma represents a cancer of substantial unmet need with steadily growing incidence. Bioengineering techniques are increasingly applied to design melanoma-specific models. Here, we summarize how extracellular and cellular elements of the melanoma tumor microenvironment have been studied in 3D cell culture models. We review the benefits of such models and address their limitations and future perspectives for the development of novel therapeutic strategies.
{"title":"Recent developments of 3D models of the tumor microenvironment for cutaneous melanoma: Bridging the gap between the bench and the bedside?","authors":"J. M. Hölken, N. Teusch","doi":"10.15761/JTS.1000388","DOIUrl":"https://doi.org/10.15761/JTS.1000388","url":null,"abstract":"In cancer drug discovery, 3D approaches have been implemented over the last years to model the complex tumor architecture and the heterogenous components of the tumor microenvironment. Cutaneous melanoma represents a cancer of substantial unmet need with steadily growing incidence. Bioengineering techniques are increasingly applied to design melanoma-specific models. Here, we summarize how extracellular and cellular elements of the melanoma tumor microenvironment have been studied in 3D cell culture models. We review the benefits of such models and address their limitations and future perspectives for the development of novel therapeutic strategies.","PeriodicalId":74000,"journal":{"name":"Journal of translational science","volume":"807 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67491531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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