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The history of albuminous nephritis. 1840. 蛋白性肾炎的病史。1840.
Pub Date : 2005-01-01 DOI: 10.1017/s0025727300071805
Pierre-François Olive Rayer
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引用次数: 3
Appendix 2 Notes on Classifications and Drawings of Nephritic Kidneys in the Nineteenth Century 附录2 19世纪肾脏病肾的分类和绘图注释
Pub Date : 2005-01-01 DOI: 10.1017/S0025727300071854
It is axiomatic that in the absence of acceptable descriptive terms that could be replicated, drawings of nephritic kidneys were a priceless asset and provided the greatest contribution to our present-day image and understanding of the types of lesions that the nineteenth century renal physicians were depicting. Although injected Malpighian corpuscles or glomeruli could be seen on the surface of the kidney using a hand lens (Rayer described them as ‘‘petits points rouges’’), prior to microscopic examination workers could only report on the crude morbid anatomical appearance of the kidney. The terms used related to size, weight, shape, colour, hardness, adherence of the capsule and the presence or absence of granulations. It is difficult to assess the value of contemporary classifications of the time unless the findings are accompanied by drawings and all the best studies did so, including those of Rayer, Bright and Martin Solon. If we compare Rayer’s extended six-form classification of nephritic kidney with Bright’s original three forms some interesting facts emerge. Most nephritic patients, other than those who survived scarlatina nephritis and were unavailable for ‘‘observations’’, died, often at different stages of the disease perhaps days, weeks or months after the onset of the nephritic process. The latter would explain the disparity in the appearances of the kidney. Bright described the three classical forms corresponding to three clinical presentations which we have simply dubbed as the ‘‘large red’’ of acute nephritis, the ‘‘large white’’ of the nephrotic syndrome and the ‘‘contracted granular’’ of chronic end stage nephritis, and remained agnostic about the existence of any other forms. Modern nephrologists are agreed that it would have been difficult at that time to improve on Bright’s classifications. One can identify these three forms within Rayer’s collection of six forms. With the advantage of hindsight it is tempting to postulate that Rayer’s extra three forms were merely examples of the Bright three but at different stages of the disease process, for example sub-acute nephritis. This hypothesis cannot be proved as nowadays nephritic patients do not usually come to post mortem and it is difficult to compare present-day biopsies with the nineteenth-century morbid anatomical appearance of the kidney. This theory may be further considered by examination of Rayer’s and Bright’s classifications and their accompanying plates. Rayer is at great pains to express in words the differences and alterations that he discusses during his post mortem ‘‘observations’’ and from his illustrated plates. The descriptions tend to be over elaborate as he searches for intermediate changes that extend the spectrum of Bright’s three basic kidneys. He places a good deal of emphasis on lobulation, which we now know is a normal variant but which could have been accentuated in a swollen kidney. Although it can never be conclusively proven it is likely that as t
显而易见的是,在缺乏可被复制的可接受的描述性术语的情况下,肾病肾脏的绘画是一笔无价之宝,为我们今天的图像和对19世纪肾脏医生所描绘的病变类型的理解提供了最大的贡献。虽然用手镜可以在肾脏表面看到注射的马尔比氏小体或肾小球(Rayer将其描述为“小点胭脂”),但在显微镜检查之前,工作人员只能报告肾脏的粗糙病态解剖外观。所用的术语与胶囊的大小、重量、形状、颜色、硬度、粘附性以及颗粒的存在与否有关。很难评估当时的当代分类的价值,除非这些发现附有图纸,所有最好的研究都是这样做的,包括雷尔、布赖特和马丁·梭伦的研究。如果我们将Rayer扩展的肾病肾六形态分类与Bright最初的三形态分类进行比较,就会发现一些有趣的事实。大多数肾病患者,除了那些在猩红热性肾炎中幸存下来并无法进行"观察"的患者外,通常在疾病的不同阶段死亡,可能在肾病过程开始后几天、几周或几个月。后者可以解释肾脏外观上的差异。Bright描述了三种典型形式对应的三种临床表现,我们简单地称之为急性肾炎的“大红色”,肾病综合征的“大白色”和慢性终末期肾炎的“收缩颗粒”,而对其他形式的存在则保持未知。现代肾病学家一致认为,在当时要改进布莱特的分类方法是很困难的。我们可以在Rayer的六种形式中识别出这三种形式。有了后见之明的优势,我们很容易假设Rayer的额外三种形式仅仅是Bright三种形式的例子,但处于疾病过程的不同阶段,例如亚急性肾炎。这个假设不能被证明,因为现在的肾病患者通常不来验尸,而且很难将现在的活组织检查与19世纪肾脏的病态解剖外观进行比较。这一理论可以通过检查Rayer和Bright的分类及其附带的板块来进一步考虑。Rayer煞费苦心地用语言表达他在他的验尸“观察”中讨论的差异和变化,以及他的插图。这些描述往往过于详尽,因为他在寻找扩展布莱特三个基本肾脏光谱的中间变化。他把重点放在了小叶化上,我们现在知道这是一种正常的变异,但在肿胀的肾脏中可能会加重。虽然它永远不能被最终证明,但很可能随着慢性疾病的进展,无论是从大的白色还是红色,肾脏变得越来越脏
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引用次数: 0
Daffy's Elixir Pamphlet 达菲长生不老药小册子
Pub Date : 2005-01-01 DOI: 10.1017/s0025727300071933
Anthony Daffy
Farr beyond any Medicament yet known, and is found so agreeable to Nature, that it effects all its Operations, as Nature would have it, and as a virtual Expedient proposed by her, for reducing all her Extreams unto an equal Temper; the same being fitted unto all Ages, Sexes, Complexions and Constitutions, and highly fortifying Nature against any noxious humour, invading or offending the Noble Parts.
它比任何已知的药物都要有效得多,而且被发现是非常适合大自然的,它可以按照大自然的意愿发挥它的一切作用,而且它实际上是大自然提出的一种权宜之计,可以使她的一切极端都趋于一致。这同样适用于所有年龄、性别、肤色和体质,并且高度强化了大自然,使其免受任何侵入或冒犯高贵部分的有害幽默的侵害。
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引用次数: 0
March 1835 1835年3月
Pub Date : 2004-01-01 DOI: 10.1017/s0025727300073579
ImagesFigure 20Figure 21
图20图21
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引用次数: 0
Walking the Paris hospitals: diary of an Edinburgh medical student, 1834-1835. 漫步巴黎医院:一位爱丁堡医学院学生的日记,1834-1835。
Pub Date : 2004-01-01
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引用次数: 0
April 1835 1835年4月
Pub Date : 2004-01-01 DOI: 10.1017/s0025727300073580
M. Chomel
ImagesFigure 22
ImagesFigure 22
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引用次数: 0
November 1834 1834年11月
Pub Date : 2004-01-01 DOI: 10.1017/s0025727300073531
ImagesFigure 1Figure 2Figure 3Figure 4Figure 5Figure 6Figure 7
图1图2图3图4图5图6图7
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引用次数: 0
December 1834 1834年12月
Pub Date : 2004-01-01 DOI: 10.1017/S0025727300073543
ImagesFigure 8Figure 9Figure 10Figure 11Figure 12
图8图9图10图11图12
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引用次数: 0
January 1835 1835年1月
Pub Date : 2004-01-01 DOI: 10.1017/s0025727300073555
ImagesFigure 13Figure 14Figure 15Figure 16Figure 17Figure 18Figure 19
图13图14图15图16图17图18图19
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引用次数: 0
June 1835 1835年6月
Pub Date : 2004-01-01 DOI: 10.1017/s0025727300073609
J. Watts, Jun, A. H. Stevens
/69r cont'd/ Monday June Jst. Come to the last month of my stay in Paris. Went to the Hotel Dieu-Roux has a case of pistol wound in a young man 1-ball entered anterior to the tendon achille's /69v/& passed out at the outer ankle, breaking the malleolus2 Tapirus[?]-the treatment is the constant application of cold-he has a case of tumor in the internal aspect of thigh three or four inches above knee-he intends operating tomorrow moming. Went on to H. St. Louis-was too late for Biett-he has commenced now making his visit at 9 o'clock-went round with Alibert-he had nothing of any importance-he is treating all his cases by local applications-he lectures on Wednesday on the Dermatoses Teignenses [sic]3-very interesting & difficult division to treat-At Me. Lachapelle's tonight had very easy manoeuvres-seizing feet of inft., when there is breech presentation-supposing, that any thing should require such an operation. Tuesday June 2nd. Went down to Hotel Dieu this morning. Went round with Breschet-nothing very particular-Roux performed extirpation of the tumor this morning-it was osteo sarcoma4 & attached by means of an osseous peduncle5 to the femur-this he was forced to cut away with the saw. Mott from New York was at the operation. A very gentlemanly looking man with something of the precise manners of a quaker about him.6 Tonight at Me. Lachapelle's we applied the crochet in presentations of lower extrem'. & hips.7 l Dupuytren had held a course at the H6tel Dieu on gunshot and sabre wounds. (Warner, Against the spirit of system, p. 115.) This would seem to indicate that the presentation of such wounds was not exactly a rare event despite the ban on duelling. 2Malleolus: ankle. This is the diminutive of malleus from its supposed resemblance to a mallet. 3Dermatoses Teignenses: dermatoses is a general term for skin diseases. Bateman criticises Alibert, to whose lectures the diarist is referring, for confusing Willan's classification of skin diseases by adopting "the ancient confusion of terms". This confusion includes his use of "les teignes" for the Willanist group of porrigos, contagious conditions, marked by the development of pustules and fever. The group includes porrigo scutulata or ringworm. (Bateman, A practical synopsis of cutaneous diseases, pp. xvi, 225-6.) 4In the entry for Sunday, November 9, 1834, the diarist writes the term as a single word: osteosarcoma. In this present case the fleshy tumour or excrescence was developing on the femur …
/6月1日星期一来谈谈我在巴黎的最后一个月。迪欧鲁酒店有一个年轻人枪伤的案例,子弹射入跟腱前,从外脚踝射出,击穿踝骨。[实战练习治疗方法是不断地冷敷。他有一个病例,大腿内侧长了一个肿瘤,在膝盖以上三、四英寸处,他打算明天上午动手术。接着去了圣路易医院——对比埃特来说已经太迟了——他现在已经开始九点钟来拜访了——和艾伯特一起去了——他没有什么重要的事——他所有的病例都是用当地的应用程序来治疗的——他星期三讲的是《德国皮肤病3》——这是一个有趣而又难以治疗的部门——在我这里。拉夏佩尔今晚的动作很简单——抓住脚掌。假如任何事情都需要进行这样的手术,那么,当有臀部出现的时候。6月2日星期二。今早去了上帝旅馆。布雷斯切去看了一遍,没有什么特别的。今天早上,鲁克斯给肿瘤做了切除手术——那是一种骨肉瘤,通过骨脚附着在股骨上——他用锯子把它锯掉了。纽约的莫特也在现场。一个看起来很绅士的人,有几分贵格会教徒的风度今晚在我。拉查佩尔的作品我们把钩针用在了“下端”的展示上。和臀部。迪普伊特伦曾在主宫举行过关于枪炮和刀伤的课程。(华纳:《反对体制精神》,第115页)这似乎表明,尽管禁止决斗,但这种伤口的出现并不罕见。2踝:脚踝。这是malleus的缩写,因为它被认为与木槌相似。皮肤病:皮肤病是皮肤病的总称。贝特曼批评阿利伯特采用“古老的术语混淆”,混淆了威兰对皮肤病的分类,而日记作者所指的正是阿利伯特的讲座。这种混淆包括他使用“les teignes”来指代Willanist组的porrigos,即以脓疱和发烧为特征的传染性疾病。这一组包括猪瘟或癣。(贝特曼:《皮肤病实用概要》,第16页,225-6页)在1834年11月9日星期日的条目中,日记作者把这个术语写成了一个词:骨肉瘤。在本病例中,肉质肿瘤或赘生物正在股骨上生长……
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Medical history. Supplement
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