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American Journal of Kidney Diseases最新文献

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More Exams, More Problems: Do We Really Need a New Accreditation System for Transplant Nephrology? 更多考试，更多问题：我们真的需要新的移植肾脏病学评审系统吗？
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-19 DOI: 10.1053/j.ajkd.2024.05.009
Samira S. Farouk , Anshul Bhalla , Meera Harhay , Laila Lakhani , Luis Sanchez Russo , Scott Sanoff , Manpreet Samra , Matthew A. Sparks , Niralee Patel , Fasika Tedla , Anju Yadav , Roslyn B. Mannon
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引用次数: 0
Visceral Abdominal Adiposity and Autosomal Dominant Polycystic Kidney Disease Progression: One More Step Toward Identifying Useful Biomarkers and Characterizing the Disease Metabolic Links 内脏腹部肥胖与常染色体显性遗传多囊肾病的进展：为确定有用的生物标记物和疾病代谢关联特征再迈出一步。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-19 DOI: 10.1053/j.ajkd.2024.05.005
Elieser Hitoshi Watanabe , Luiz Fernando Onuchic
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引用次数: 0
Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group 推进肾脏疾病的基因检测：国家肾脏基金会工作组的报告。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-19 DOI: 10.1053/j.ajkd.2024.05.010
Nora Franceschini, David L. Feldman, Jonathan S. Berg, Whitney Besse, Alexander R. Chang, Neera K. Dahl, Rasheed Gbadegesin, Martin R. Pollak, Hila Milo Rasouly, Richard J.H. Smith, Cheryl A. Winkler, Ali G. Gharavi
About 37 million people in the United States have chronic kidney disease, a disease that encompasses multiple causes. About 10% or more of kidney diseases in adults and as many as 70% of selected chronic kidney diseases in children are expected to be explained by genetic causes. Despite the advances in genetic testing and an increasing understanding of the genetic bases of certain kidney diseases, genetic testing in nephrology lags behind other medical fields. More understanding of the benefits and logistics of genetic testing is needed to advance the implementation of genetic testing in chronic kidney diseases. Accordingly, the National Kidney Foundation convened a Working Group of experts with diverse expertise in genetics, nephrology, and allied fields to develop recommendations for genetic testing for monogenic disorders and to identify genetic risk factors for oligogenic and polygenic causes of kidney diseases. Algorithms for clinical decision making on genetic testing and a road map for advancing genetic testing in kidney diseases were generated. An important aspect of this initiative was the use of a modified Delphi process to reach group consensus on the recommendations. The recommendations and resources described herein provide support to nephrologists and allied health professionals to advance the use of genetic testing for diagnosis and screening of kidney diseases.
美国约有 3700 万人患有慢性肾脏病，这是一种由多种原因引起的疾病。预计大约 10%或更多的成人肾脏疾病和大约 70%的儿童慢性肾脏疾病可由遗传原因引起。尽管基因检测技术不断进步，人们对某些肾脏疾病的基因基础也有了更多了解，但肾脏病学的基因检测仍落后于其他医学领域。要推进慢性肾脏病基因检测的实施，需要对基因检测的益处和后勤工作有更多的了解。因此，全美肾脏基金会召集了一个由遗传学、肾脏病学和相关领域具有不同专业知识的专家组成的工作组，以制定单基因疾病基因检测的建议，并确定导致肾脏疾病的少基因和多基因遗传风险因素。此外，还制定了基因检测临床决策算法和推进肾脏疾病基因检测的路线图。这项工作的一个重要方面是采用了改良的德尔菲程序，以就建议达成小组共识。本文所述的建议和资源为肾病学家和专职医疗人员提供了支持，以推动基因检测在肾脏疾病诊断和筛查中的应用。
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引用次数: 0
The Impact of Obesity on Glomerular Diseases Remains to be Determined 肥胖对肾小球疾病的影响仍有待确定。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-17 DOI: 10.1053/j.ajkd.2024.06.004
Luis Yu , Niels Olsen Saraiva Câmara
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引用次数: 0
Transplanting Identities 移植身份。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-17 DOI: 10.1053/j.ajkd.2024.01.528
Tarek Zieneldien BS
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引用次数: 0
Antioxidants for Adults With CKD: Editorial Summary of a Cochrane Review 成人慢性肾脏病患者的抗氧化剂。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-11 DOI: 10.1053/j.ajkd.2023.12.026
Julia M.T. Colombijn, Robin W.M. Vernooij
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引用次数: 0
Clonal Hematopoiesis and Acute Kidney Injury Risk: Inflammatory Macrophages Implicated 克隆性造血与急性肾损伤风险：炎症性巨噬细胞参与其中
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-10 DOI: 10.1053/j.ajkd.2024.06.007
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引用次数: 0
Revisiting Antioxidants in CKD: Still No Consensus 重新审视慢性肾脏病中的抗氧化剂：仍未达成共识。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-10 DOI: 10.1053/j.ajkd.2024.06.009
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引用次数: 0
Use of Pragmatic Trials to Improve Implementation of Best Practices for CKD 利用实用性试验改进慢性肾脏病最佳治疗方法的实施。
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-10 DOI: 10.1053/j.ajkd.2024.06.008
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引用次数: 0
Genetic Insights into Blood Pressure From Kidney Multi-Omics 从肾脏多基因组学了解血压的遗传学知识
IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY
American Journal of Kidney Diseases
Pub Date : 2024-07-08 DOI: 10.1053/j.ajkd.2024.06.006
Chenyu Li, Katalin Susztak
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引用次数: 0
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