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Detecting and tracking depression through temporal topic modeling of tweets: insights from a 180-day study 通过tweet的时间主题建模来检测和跟踪抑郁症:来自180天研究的见解
Pub Date : 2024-12-06 DOI: 10.1038/s44184-024-00107-5
Ranganathan Chandrasekaran, Suhas Kotaki, Abhilash Hosaagrahaara Nagaraja
Depression affects over 280 million people globally, yet many cases remain undiagnosed or untreated due to stigma and lack of awareness. Social media platforms like X (formerly Twitter) offer a way to monitor and analyze depression markers. This study analyzes Twitter data 90 days before and 90 days after a self-disclosed clinical diagnosis. We gathered 246,637 tweets from 229 diagnosed users. CorEx topic modeling identified seven themes: causes, physical symptoms, mental symptoms, swear words, treatment, coping/support mechanisms, and lifestyle, and conditional logistic regression assessed the odds of these themes occurring post-diagnosis. A control group of healthy users (284,772 tweets) was used to develop and evaluate machine learning classifiers—support vector machines, naive Bayes, and logistic regression—to distinguish between depressed and non-depressed users. Logistic regression and SVM performed best. These findings show the potential of Twitter data for tracking depression and changes in symptoms, coping mechanisms, and treatment use.
抑郁症影响着全球超过2.8亿人,但由于污名化和缺乏认识,许多病例仍未得到诊断或治疗。像X(以前的Twitter)这样的社交媒体平台提供了一种监测和分析抑郁症标志物的方法。本研究分析了自我披露的临床诊断前90天和后90天的Twitter数据。我们从229名确诊用户那里收集了246637条推文。CorEx主题建模确定了7个主题:病因、身体症状、精神症状、脏话、治疗、应对/支持机制和生活方式,条件逻辑回归评估了这些主题在诊断后发生的几率。健康用户的控制组(284,772条推文)被用来开发和评估机器学习分类器——支持向量机、朴素贝叶斯和逻辑回归——以区分抑郁和非抑郁用户。逻辑回归和支持向量机表现最好。这些发现显示了Twitter数据在追踪抑郁症状、应对机制和治疗使用方面的潜力。
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引用次数: 0
Exploring digital use, happiness, and loneliness in Japan with the experience sampling method 用体验抽样法探索日本的数字使用、幸福和孤独
Pub Date : 2024-12-06 DOI: 10.1038/s44184-024-00108-4
Yijun Chen, Xiaochu Zhang, Rei Akaishi
Smartphones have become an integral part of modern life, raising concerns about their impact on mental health, especially among young people. However, previous studies yielded inconsistent results, possibly due to neglecting the possibility of interactions between offline and online communications. To explore potential interactions among different communication modes (online vs. offline) and communication types (private vs. public), we adopted the experience sampling method to track 418 Japanese individuals over 21 days and analyzed the data using multilevel models and psychometric network models. The findings revealed that digital use has only small direct effects on happiness and loneliness, especially through public (one-to-many) online communication. The increased digital use reduced offline communication time, indirectly influencing loneliness to a large degree. Overall, this study highlights the indirect effects of decreased face-to-face communication and the significant role of one-to-many online communication, which may explain a part of the diverse findings on this issue.
智能手机已经成为现代生活中不可或缺的一部分,人们开始担心智能手机对心理健康的影响,尤其是对年轻人的影响。然而,之前的研究得出了不一致的结果,可能是由于忽略了离线和在线交流之间互动的可能性。为了探索不同沟通方式(线上与线下)和沟通类型(私人与公共)之间潜在的互动,我们采用经验抽样法对418名日本人进行了为期21天的跟踪调查,并使用多层次模型和心理测量网络模型对数据进行了分析。研究结果显示,数字产品的使用对幸福感和孤独感的直接影响很小,尤其是通过公开的(一对多)在线交流。数字使用的增加减少了线下交流的时间,在很大程度上间接影响了孤独感。总的来说,本研究强调了面对面交流减少的间接影响和一对多在线交流的重要作用,这可能解释了这一问题的不同发现的一部分。
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引用次数: 0
Deep learning models can predict violence and threats against healthcare providers using clinical notes 深度学习模型可以根据临床记录预测针对医疗服务提供者的暴力和威胁。
Pub Date : 2024-12-05 DOI: 10.1038/s44184-024-00105-7
Nicholas J. Dobbins, Jacqueline Chipkin, Tim Byrne, Omar Ghabra, Julia Siar, Mitchell Sauder, R. Michael Huijon, Taylor M. Black
Violence, verbal abuse, threats, and sexual harassment of healthcare providers by patients is a major challenge for healthcare organizations around the world, contributing to staff turnover, distress, absenteeism, reduced job satisfaction, and worsening mental and physical health. To enable interventions prior to possible violent episodes, we trained two deep learning models to predict violence against healthcare workers 3 days prior to violent events for case and control patients. The first model is a document classification model using clinical notes, and the second is a baseline regression model using largely structured data. Our document classification model achieved an F1 score of 0.75 while our model using structured data achieved an F1 of 0.72, both exceeding the predictive performance of a psychiatry team who reviewed the same documents (0.5 F1). To aid in the explainability and understanding of risk factors for violent events, we additionally trained a named entity recognition classifier on annotations of the same corpus, which achieved an overall F1 of 0.7. This study demonstrates the first deep learning model capable of predicting violent events within healthcare settings using clinical notes, surpassing the first published baseline of human experts. We anticipate our methods can be generalized and extended to enable intervention at other hospital systems.
患者对医疗保健提供者的暴力、言语虐待、威胁和性骚扰是世界各地医疗保健组织面临的主要挑战,导致员工离职、痛苦、缺勤、工作满意度降低以及身心健康恶化。为了在可能的暴力事件发生之前进行干预,我们训练了两个深度学习模型,以在病例和对照患者的暴力事件发生前3天预测针对医护人员的暴力行为。第一个模型是使用临床记录的文档分类模型,第二个模型是使用大量结构化数据的基线回归模型。我们的文档分类模型的F1得分为0.75,而我们使用结构化数据的模型的F1得分为0.72,两者都超过了审查相同文档的精神病学团队的预测性能(0.5 F1)。为了帮助解释和理解暴力事件的风险因素,我们在同一语料库的注释上额外训练了一个命名实体识别分类器,其总体F1达到0.7。这项研究展示了第一个能够使用临床记录预测医疗保健环境中的暴力事件的深度学习模型,超过了人类专家首次发布的基线。我们期望我们的方法可以推广和扩展到其他医院系统的干预。
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引用次数: 0
Development of the psychopathological vulnerability index for screening at-risk youths: a Rasch model approach 发展的精神病理脆弱性指数筛选有风险的青年:一个Rasch模型方法。
Pub Date : 2024-12-02 DOI: 10.1038/s44184-024-00106-6
Yujing Liao, Haitao Shen, Wenjie Duan, Shanshan Cui, Chunxiu Zheng, Rong Liu, Yawen Jia
Accumulating research on mental health emphasizes the general factor of psychopathology (p-factor) that unites various mental health issues. This study develops a psychopathological vulnerability assessment for youths, evaluating its psychometric properties and clinical utility. An umbrella review conceptualized multifactor psychopathological vulnerability, leading to a 57-item pool. A total of 11,224 individuals participated in this study. The resulting 22-item psychopathological vulnerability index (PVI) fitted the unidimensional Rasch model, demonstrating a person separation reliability of 0.78 and a Cronbach’s alpha of 0.84. Cut-off points of 11 and 5, derived from latent class analysis, were used to distinguish vulnerable and high-protection populations. The PVI’s concurrent and predictive hit rates ranged from 36.00% to 53.57% in clinical samples. The PVI concretized the vulnerability–stress model for identifying at-risk youths and may facilitate universal interventions by integrating the theoretical foundations of bifactor S-1 models with key symptoms from network models for theoretically grounded approaches.
越来越多的心理健康研究强调精神病理学的一般因素(p-factor),它将各种心理健康问题联系在一起。本研究发展青少年心理病理脆弱性评估,评估其心理测量特性和临床应用。一项总括性的综述概念化了多因素的精神病理脆弱性,得出了一个57项的分类。共有11,224人参与了这项研究。所得的22项心理病理脆弱性指数(PVI)符合一维Rasch模型,个体分离信度为0.78,Cronbach's alpha为0.84。从潜在分类分析中得出的截断点11和5用于区分脆弱人群和高保护人群。在临床样本中,PVI的并发和预测命中率从36.00%到53.57%不等。PVI具体化了识别高危青少年的脆弱性-压力模型,并可能通过将双因素S-1模型的理论基础与理论基础方法的网络模型的关键症状相结合,促进普遍干预。
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引用次数: 0
Symptomatic associations and sexual differences in depression and communication 抑郁和沟通的症状关联和性别差异
Pub Date : 2024-11-30 DOI: 10.1038/s44184-024-00098-3
Yu Jin, Yinjie Fan, Jian He, Amanda Wilson, Yi Li, Jiaqi Li, Yajun Bu, Yuanyuan Wang
Previous studies have explored the associations between parental and offspring’s depression and parent-child communication. However, few studies have investigated their symptomatic associations and potential sex differences. Therefore, this study aims to examine their associations and sex differences in parents and offspring. Based on the China Family Panel Studies (CFPS)-2020 study, depressive symptoms and parent-child communication were measured by the 8-item Center for Epidemiologic Studies Depression Scale (CESD-8) and independent questions, respectively. Network analysis was used to investigate the associations and to compare the sex differences of parents and offspring. A total of 1710 adolescents were included after cleaning process (N = 28,530). There were significantly stronger associations in boys’ “anhedonia” and “arguments with parents”, and in girls’ “happiness” and parents’ “joyfulness”. Furthermore, there were same-sex depression associations between children and parents (e.g., boys’ “despair”–fathers’ “joyfulness”; girls’ “anhedonia”–mothers’ “loneliness”). These results would help us to better understand the in depression and communication nuanced associations and to develop effective strategies for improving parental and offspring’s mental health.
以往的研究已经探讨了父母和子女的抑郁与亲子沟通之间的关系。然而,很少有研究调查它们的症状关联和潜在的性别差异。因此,本研究旨在研究它们的关联以及父母和后代的性别差异。基于中国家庭小组研究(CFPS)-2020研究,分别采用8项流行病学研究中心抑郁量表(CESD-8)和独立问卷对抑郁症状和亲子沟通进行测量。研究人员利用网络分析的方法来研究这种关联,并比较父母和后代的性别差异。清洗后共纳入1710名青少年(N = 28,530)。男孩的“快感缺乏”和“与父母争吵”,女孩的“幸福”和父母的“快乐”之间存在明显更强的关联。此外,孩子和父母之间存在同性抑郁的关联(例如,男孩的“绝望”-父亲的“快乐”;女孩的“快感缺乏症”——母亲的“孤独”)。这些结果将有助于我们更好地理解抑郁和沟通之间的微妙联系,并制定有效的策略来改善父母和后代的心理健康。
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引用次数: 0
Longitudinal trajectories of symptom change during antidepressant treatment among managed care patients with depression and anxiety 管理式医疗抑郁症和焦虑症患者在抗抑郁治疗期间症状变化的纵向轨迹
Pub Date : 2024-11-27 DOI: 10.1038/s44184-024-00104-8
Judith Cukor, Zhenxing Xu, Veer Vekaria, Fei Wang, Mark Olfson, Samprit Banerjee, Gregory Simon, George Alexopoulos, Jyotishman Pathak
Despite the high correlation between anxiety and depression, little remains known about the course of each condition when presenting concurrently. This study aimed to identify longitudinal patterns during antidepressant treatment in patients with depression and anxiety, and evaluate related factors associated with these patterns. By analyzing longitudinal self-report Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) scores that tracked courses of depression and anxiety over a three-month window among the 577 adult participants, six depression and six anxiety trajectory subgroups were computationally derived using group-based trajectory modeling. Three depression subgroups showed symptom improvement, while three showed nonresponses. Similar patterns were observed in the six anxiety subgroups. Multinomial regression was used to associate patient characteristics with trajectory subgroup membership. Compared to patients in the remission group, factors associated with depressive symptom nonresponse included older age and lower depression severity.
尽管焦虑和抑郁之间存在高度相关性,但人们对这两种疾病同时出现时的病程仍然知之甚少。本研究旨在确定抑郁症和焦虑症患者在抗抑郁治疗期间的纵向模式,并评估与这些模式相关的因素。通过分析 577 名成年参与者的患者健康问卷-9(PHQ-9)和一般焦虑症-7(GAD-7)纵向自我报告得分,追踪抑郁和焦虑症患者在三个月时间内的治疗过程,利用基于群体的轨迹建模计算得出了六个抑郁和六个焦虑症轨迹亚组。三个抑郁亚组的症状有所改善,而三个亚组则无反应。在六个焦虑症分组中也观察到了类似的模式。多项式回归用于将患者特征与轨迹亚组成员联系起来。与缓解组患者相比,与抑郁症状无反应相关的因素包括年龄较大和抑郁严重程度较低。
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引用次数: 0
Impact of pandemic-related worries on mental health in India from 2020 to 2022 2020 至 2022 年大流行相关担忧对印度心理健康的影响
Pub Date : 2024-11-24 DOI: 10.1038/s44184-024-00101-x
Youqi Yang, Anqi Sun, Lauren Zimmermann, Bhramar Mukherjee
This study examines how pandemic-related worries affected mental health in India’s adults from 2020 to 2022. Using data from the Global COVID-19 Trends and Impact Survey (N = 2,576,174), it explores the associations between worry variables (financial stress, food insecurity, and COVID-19-related health worries) and self-reported symptoms of depression and anxiety. Our analysis, based on complete cases (N = 747,996), used survey-weighted models, adjusting for demographics and calendar time. The study finds significant associations between these worries and mental health outcomes, with financial stress being the most significant factor affecting both depression (adjusted odds ratio, aOR: 2.36; 95% confidence interval, CI: [2.27, 2.46]) and anxiety (aOR: 1.91; 95% CI: [1.81, 2.01])). Models with interaction terms revealed gender, residential status, and calendar time as effect modifiers. This study demonstrates that social media platforms like Facebook can effectively gather large-scale survey data to track mental health trends during public health crises.
本研究探讨了 2020 年至 2022 年与大流行相关的担忧如何影响印度成年人的心理健康。研究利用全球 COVID-19 趋势和影响调查(N = 2,576,174 人)的数据,探讨了担忧变量(经济压力、粮食不安全和 COVID-19 相关健康担忧)与自我报告的抑郁和焦虑症状之间的关联。我们的分析以完整病例(N = 747,996 例)为基础,采用调查加权模型,并对人口统计学和日历时间进行了调整。研究发现,这些担忧与心理健康结果之间存在明显关联,其中经济压力是影响抑郁(调整后赔率:2.36;95% 置信区间:[2.27, 2.46])和焦虑(调整后赔率:1.91;95% 置信区间:[1.81, 2.01])的最重要因素。)带有交互项的模型显示,性别、居住状况和日历时间是影响调节因素。这项研究表明,Facebook 等社交媒体平台可以有效地收集大规模调查数据,以跟踪公共卫生危机期间的心理健康趋势。
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引用次数: 0
Using hidden Markov modelling to reveal in-session stages in text-based counselling 使用隐马尔可夫模型揭示基于文本的咨询中的会话阶段。
Pub Date : 2024-11-21 DOI: 10.1038/s44184-024-00103-9
Ziru Fu, Yu Cheng Hsu, Christian S. Chan, Joyce Liu, Paul S. F. Yip
Counselling sessions have multiple stages, each with its themes and objectives. This study aimed to apply Hidden Markov Models (HMMs) to analyse counselling sessions from Open Up, an online text-based counselling platform in Hong Kong. The focus was on inferring latent stages over word distributions and identifying distinctive patterns of progression in more versus less satisfying sessions. Transcripts from 2589 sessions were categorized into more satisfying sessions ( $$n=mathrm{1993}$$ ) and less satisfying sessions ( $$n=596$$ ) based on post-session surveys. A message-level HMM identified five distinct stages: Rapport-building, Problem-identification, Problem-exploration, Problem-solving, and Wrap-up. Compared with less satisfying sessions, more satisfying sessions saw significantly more efficient initial rapport building (7.5% of session duration), problem introduction (20.2%), problem exploration (28.5%), elaborated solution development (46.6%), and concise conclusion (8.2%). This study offers insights for improving the efficiency and satisfaction of text-based counselling services through efficient initial engagement, thorough issue exploration, and focused problem-solving.
咨询过程分为多个阶段,每个阶段都有自己的主题和目标。本研究旨在应用隐马尔可夫模型(HMMs)分析香港在线文本咨询平台 Open Up 的咨询过程。研究的重点是推断单词分布的潜在阶段,并识别满意度较高与较低的会话中的独特进展模式。根据会后调查,来自 2589 个会话的文字记录被分为满意度较高的会话(n = 1993)和满意度较低的会话(n = 596)。信息级 HMM 确定了五个不同的阶段:建立关系、发现问题、探索问题、解决问题和总结。与满意度较低的会话相比,满意度较高的会话在初步建立友好关系(占会话时间的 7.5%)、问题介绍(20.2%)、问题探索(28.5%)、详细制定解决方案(46.6%)和简明总结(8.2%)方面的效率明显更高。这项研究为通过高效的初步接触、彻底的问题探索和集中的问题解决来提高基于文本的咨询服务的效率和满意度提供了启示。
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引用次数: 0
Infrastructure development in children’s behavioral health systems of care: essential elements and implementation strategies 儿童行为健康护理系统的基础设施建设:基本要素和实施策略。
Pub Date : 2024-11-14 DOI: 10.1038/s44184-024-00102-w
Jeffrey J. Vanderploeg
To improve the outcomes of children’s behavioral health systems, states must invest in expanding infrastructure; however, infrastructure is a commonly used and poorly understood concept. This paper aims to provide a definition of infrastructure in the context of state-level children’s behavioral system of care development and describes five essential infrastructure elements: an integrated governance and decision-making structure; structures and processes for blended and braided funding; a central point of access for information, referral, and linkage; workforce development, training, and coaching in effective practices; and data and quality improvement mechanisms. Suggested implementation activities are offered for each of the five proposed infrastructure components. The important role of public-private partnership, particularly with intermediary organizations, is described, and future directions for research and scholarship are proposed.
为了改善儿童行为健康系统的成果,各州必须投资扩大基础设施;然而,基础设施是一个常用但理解不深的概念。本文旨在提供州级儿童行为医疗系统发展背景下基础设施的定义,并描述了五个基本的基础设施要素:综合治理和决策结构;混合和编织资金的结构和流程;信息、转诊和联系的中心接入点;劳动力发展、培训和有效实践的辅导;以及数据和质量改进机制。针对五个拟议的基础设施组成部分,分别提出了实施活动建议。介绍了公私合作伙伴关系的重要作用,特别是与中介组织的合作,并提出了未来的研究和学术方向。
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引用次数: 0
Mental health care needs of caregivers of people with Alzheimer’s disease from online forum analysis 从网上论坛分析老年痴呆症患者照顾者的心理保健需求。
Pub Date : 2024-11-14 DOI: 10.1038/s44184-024-00100-y
Jiyeong Kim, Zhuo Ran Cai, Michael L. Chen, Shawheen J. Rezaei, Sonia Onyeka, Carolyn I. Rodriguez, Tina Hernandez-Boussard, Vladimir Filkov, Rachel A. Whitmer, Eleni Linos, Yong K. Choi
Informal caregivers of people with Alzheimer’s disease and related dementias (ADRD) are at risk of poor mental health. This study aimed to investigate the feasibility and validity of studying caregivers’ mental stressors using online caregiving forum data (March 2018–February 2022) and natural language processing and machine learning (NLP/ML). NLP/ML topic modeling generated eight prominent topics, which we compared with qualitatively defined themes and the existing caregiving framework to assess validity. Among a total of 60,182 posts, 5848 were mental distress-related; for the ADRD patients (symptoms, medication, relocation, care duty share, diagnosis, conversation strategy) and the caregivers (caregiving burden and support). While we observed novel topics from NLP/ML-defined topics, mostly those were aligned with the existing framework. For feasibility assessment, qualitative title screening was done. The findings shed new light on the potential of NLP/ML text analysis of the online forum for informal caregivers to prepare tailored support for this vulnerable population.
阿尔茨海默病及相关痴呆症(ADRD)患者的非正规护理者面临着心理健康状况不佳的风险。本研究旨在利用在线照护论坛数据(2018 年 3 月至 2022 年 2 月)以及自然语言处理和机器学习(NLP/ML)研究照护者的精神压力源的可行性和有效性。NLP/ML 主题建模生成了八个突出主题,我们将其与定性定义的主题和现有的护理框架进行了比较,以评估其有效性。在总共 60,182 个帖子中,有 5848 个帖子与精神痛苦有关;这些帖子分别针对 ADRD 患者(症状、用药、搬迁、护理责任分担、诊断、谈话策略)和护理人员(护理负担和支持)。虽然我们从 NLP/ML 定义的主题中发现了新颖的主题,但这些主题大多与现有框架一致。为了评估可行性,我们进行了定性标题筛选。研究结果揭示了对非正式护理人员在线论坛进行 NLP/ML 文本分析的潜力,从而为这一弱势群体提供量身定制的支持。
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引用次数: 0
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Npj mental health research
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