Miao-Miao Wang, Xing-jin Wang, Ying Meng, Fang Wang, H. Ye
{"title":"The live birth rate improved when the endometrial thickness decreased from the HCG day to the embryo transfer day. A retrospective cohort study of 9572 fresh embryo transfer cycles","authors":"Miao-Miao Wang, Xing-jin Wang, Ying Meng, Fang Wang, H. Ye","doi":"10.26502/ogr0118","DOIUrl":"https://doi.org/10.26502/ogr0118","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-12-22DOI: 10.26502/ogr0145
Pankaj Yadav, Dong-Bao Chen, Sathish Kumar
Hydrogen sulfide (H2S) is a cardiovascular signaling molecule that causes vasodilation in vascular smooth muscle cells, but its mechanism is unclear. We examined how H2S affects mesenteric and uterine arteries without endothelium in nonpregnant and pregnant rats and the underlying mechanisms. H2S donors GYY4137 and NaHS relaxed uterine arteries more than mesenteric arteries in both pregnant and nonpregnant rats. GYY4137 and NaHS caused greater relaxation in the uterine artery of pregnant versus nonpregnant rats. High extracellular K+ abolished NaHS relaxation in pregnant uterine arteries, indicating potassium channel involvement. NaHS relaxation was unaffected by voltage-gated potassium channel blockers, reduced by ATP-sensitive potassium channel blockers, and abolished by calcium-activated potassium (BKCa) channel blockers. Thiol-reductant dithiothreitol also prevented NaHS relaxation. Thus, H2S has region-specific and pregnancy-enhanced vasodilator effects in the uterine arteries, mainly mediated by BKCa channels and sulfhydration.
{"title":"Region-Specific and Pregnancy-Enhanced Vasodilator Effects of Hydrogen Sulfide.","authors":"Pankaj Yadav, Dong-Bao Chen, Sathish Kumar","doi":"10.26502/ogr0145","DOIUrl":"10.26502/ogr0145","url":null,"abstract":"<p><p>Hydrogen sulfide (H<sub>2</sub>S) is a cardiovascular signaling molecule that causes vasodilation in vascular smooth muscle cells, but its mechanism is unclear. We examined how H<sub>2</sub>S affects mesenteric and uterine arteries without endothelium in nonpregnant and pregnant rats and the underlying mechanisms. H<sub>2</sub>S donors GYY4137 and NaHS relaxed uterine arteries more than mesenteric arteries in both pregnant and nonpregnant rats. GYY4137 and NaHS caused greater relaxation in the uterine artery of pregnant versus nonpregnant rats. High extracellular K<sup>+</sup> abolished NaHS relaxation in pregnant uterine arteries, indicating potassium channel involvement. NaHS relaxation was unaffected by voltage-gated potassium channel blockers, reduced by ATP-sensitive potassium channel blockers, and abolished by calcium-activated potassium (BK<sub>Ca</sub>) channel blockers. Thiol-reductant dithiothreitol also prevented NaHS relaxation. Thus, H<sub>2</sub>S has region-specific and pregnancy-enhanced vasodilator effects in the uterine arteries, mainly mediated by BK<sub>Ca</sub> channels and sulfhydration.</p>","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"6 4","pages":"309-316"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10824528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Illa, L. Pla, C. Loreiro, C. Miranda, M. Mayol, B. Kühne, M. Barenys, E. Gratacós, E. Eixarch
{"title":"Neonatal Effects of Maternal Supplementation with Docosahexaenoic Acid and Lactoferrin on the Fetal Brain and Placenta in a Rabbit Model of Intrauterine Growth Restriction","authors":"M. Illa, L. Pla, C. Loreiro, C. Miranda, M. Mayol, B. Kühne, M. Barenys, E. Gratacós, E. Eixarch","doi":"10.26502/ogr0108","DOIUrl":"https://doi.org/10.26502/ogr0108","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69351960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Induction of Labour in a Patient with Antepartum Eclampsia: A Case Report and Literature Review","authors":"Valentina Zanin, M. Angelini, L. Driul","doi":"10.26502/ogr0125","DOIUrl":"https://doi.org/10.26502/ogr0125","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Population issue has always been a major topic in national development. Female infertility is one of the factors leading to demographic problems. Literature review was done in order to realize how far researchers have reached among area of human adipose derived stem cells’(ADSC) usage in female infertility treatment. It seems that not all diseases are fit to ADSC therapy. In terms of polycystic ovary syndrome, endometriosis, intrauterine adhesion and premature ovarian failure, existed researches have shown the promising prospect of ADSC treatment. Further researches should be carried out in the future in order to clarify how ADSC can treat infertility-related diseases and eventually apply ADSC to clinical practice
{"title":"Human Adipose Derived Stem Cells in Female Infertility Treatment","authors":"Tao Sun, Zhuo-min Wang, Yuxian Wang, Ying Gu, Qianyu Hu, Jian Xu","doi":"10.26502/ogr0135","DOIUrl":"https://doi.org/10.26502/ogr0135","url":null,"abstract":"Population issue has always been a major topic in national development. Female infertility is one of the factors leading to demographic problems. Literature review was done in order to realize how far researchers have reached among area of human adipose derived stem cells’(ADSC) usage in female infertility treatment. It seems that not all diseases are fit to ADSC therapy. In terms of polycystic ovary syndrome, endometriosis, intrauterine adhesion and premature ovarian failure, existed researches have shown the promising prospect of ADSC treatment. Further researches should be carried out in the future in order to clarify how ADSC can treat infertility-related diseases and eventually apply ADSC to clinical practice","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chitra Bamba, M. Rohilla, Anuradha Kumari, A. Kaur, P. Srivastava
{"title":"Effect of Forkhead Box Protein 3 Gene Polymorphisms in Recurrent Pregnancy Loss: A meta-analysis","authors":"Chitra Bamba, M. Rohilla, Anuradha Kumari, A. Kaur, P. Srivastava","doi":"10.26502/ogr0109","DOIUrl":"https://doi.org/10.26502/ogr0109","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69351990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Success of Vaginal Birth after Cesarean Section (VBAC) based on Previous Cesarean Delivery Indication in a Tertiary University Hospital: A Five Year Retrospective Study","authors":"John Edward O. Tanchuco, Chiaoling Sua Lao","doi":"10.26502/ogr0113","DOIUrl":"https://doi.org/10.26502/ogr0113","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To assess patient centered outcomes associated with use of the Medela INVIA Motion prophylactic negative pressure wound therapy (NPWT) system at cesarean delivery. Methods: This was a single arm trial including patients undergoing scheduled or unscheduled cesarean delivery at or greater than 23 weeks’ gestation. Patients unwilling to provide consent, unavailable for follow up or with a contraindication use of prophylactic NPWT were excluded. Consented patients had the Medela INVIA Motion prophylactic NPWT system placed and secured after skin closure. The device was removed at discharge (typically postoperative day 3-4). Patient reported outcomes were pain scores on a scale of 0 (no pain) to 10 (worst pain) and patient satisfaction scores on a scale of 0 (completely dissatisfied) to 10 (completely satisfied) at discharge and postoperative day 30. Other outcomes were a composite of wound complication including wound infection, would separation, seroma, antibiotics prescribed for presumed surgical site infection within 30 days, and occurrence of adverse skin reactions potentially related use of prophylactic NPWT. Results: A total of 20 patients undergoing cesarean delivery were included. The average body mass index at delivery was 37 kg/m 2 . All patients had routine infection prevention measures. Nearly all patients had a Pfannenstiel incision skin incision. Pain scores were generally low at the time of discharge (median score 2.5 [IQR 1, 5]) and near 0 by postoperative day 30 (median 0 [IQR 0, 1]). Patients were very satisfied with their experience using the Medela INVIA Motion prophylactic NPWT at discharge (median score 10 [IQR 8.5, 10]) and postoperative day 30 (median score 10 [IQR 10, 10]). There was no wound complication or adverse skin reaction. Conclusion:
{"title":"Prophylactic Negative Pressure Wound Therapy with the Medela Invia Motion at Cesarean Delivery: a Pilot Study","authors":"Ryan N. Kuuseg, Methodius G. Tuuli","doi":"10.26502/ogr0136","DOIUrl":"https://doi.org/10.26502/ogr0136","url":null,"abstract":"Objective: To assess patient centered outcomes associated with use of the Medela INVIA Motion prophylactic negative pressure wound therapy (NPWT) system at cesarean delivery. Methods: This was a single arm trial including patients undergoing scheduled or unscheduled cesarean delivery at or greater than 23 weeks’ gestation. Patients unwilling to provide consent, unavailable for follow up or with a contraindication use of prophylactic NPWT were excluded. Consented patients had the Medela INVIA Motion prophylactic NPWT system placed and secured after skin closure. The device was removed at discharge (typically postoperative day 3-4). Patient reported outcomes were pain scores on a scale of 0 (no pain) to 10 (worst pain) and patient satisfaction scores on a scale of 0 (completely dissatisfied) to 10 (completely satisfied) at discharge and postoperative day 30. Other outcomes were a composite of wound complication including wound infection, would separation, seroma, antibiotics prescribed for presumed surgical site infection within 30 days, and occurrence of adverse skin reactions potentially related use of prophylactic NPWT. Results: A total of 20 patients undergoing cesarean delivery were included. The average body mass index at delivery was 37 kg/m 2 . All patients had routine infection prevention measures. Nearly all patients had a Pfannenstiel incision skin incision. Pain scores were generally low at the time of discharge (median score 2.5 [IQR 1, 5]) and near 0 by postoperative day 30 (median 0 [IQR 0, 1]). Patients were very satisfied with their experience using the Medela INVIA Motion prophylactic NPWT at discharge (median score 10 [IQR 8.5, 10]) and postoperative day 30 (median score 10 [IQR 10, 10]). There was no wound complication or adverse skin reaction. Conclusion:","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rare Ovarian Steroid Cell Tumor, Not Otherwise Specified (NOS) With Massive Ascites and Elevated CA125: A Case Report","authors":"Yiqun Tang, D. Chu, Yanli Li, B. Cai, S. Shi","doi":"10.26502/ogr0126","DOIUrl":"https://doi.org/10.26502/ogr0126","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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