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Effect of Behavior Change Communication through the Health Development Army on Dietary Practice of Pregnant Women in Ambo District, Ethiopia: A Cluster Randomized Controlled Community Trial 通过健康发展部队进行的行为改变交流对埃塞俄比亚安博地区孕妇饮食习惯的影响:一项整群随机对照社区试验
Pub Date : 2022-01-01 DOI: 10.26502/ogr096
Mitsiwat Abebe Gebremichael, T. B. Lema
Background: Given how important pregnancy is to a woman's life, both the mother's and the unborn child's health and wellbeing are greatly influenced by the mother's dietary habits during and throughout pregnancy. Therefore, the objective of the study was to investigate the effect of behavior change communication (BCC) through the health development armies on the dietary practices of pregnant women. Methods: A two-arm parallel cluster randomized controlled community trial with baseline and endline measurements using quantitative data collection methods was conducted in Ambo district among 770 pregnant women (385 in control and 385 in intervention groups). Endpoint data from 372 intervention and 372 control groups were gathered, respectively. In the intervention group, health development armies delivered the BCC main message based on intervention protocol. The intervention began in July 2018, and data collection for the endline began in October, 2018. The control group received the standard care provided by the healthcare system during an ANC visit. The study of effect measure was done using a log-binomial model to estimate the adjusted relative risk and its 95% confidence interval (CI) of the risk factors for suboptimal dietary practice. Result: At the end of the study, the overall optimal dietary practice among the intervention group was 65.1%, while among the control group it was 34.9% (p< 0.001). Pregnant women who received intervention were 41.0% less likely to be at risk of being suboptimal in dietary practice compared to pregnant women who were in the control group (ARR = 0.591, 95%CI: 0.510-0.686). Conclusions: This study revealed that behavior change communication (BCC) through the health development armies is effective in improving the dietary practices of pregnant women. As a result, BCC through the Health Development Army is recommended to enhance the dietary practices of pregnant women.
背景:考虑到怀孕对妇女的生活有多么重要,母亲和未出生的孩子的健康和幸福在怀孕期间和整个怀孕期间都受到母亲饮食习惯的极大影响。因此,本研究的目的是探讨行为改变沟通(BCC)通过健康发展军队对孕妇饮食习惯的影响。方法:采用定量数据收集方法,在安博地区对770名孕妇(对照组385名,干预组385名)进行平行双组随机对照社区试验。分别收集了372个干预组和372个对照组的终点数据。在干预组,卫生发展部队根据干预方案传递BCC主要信息。干预于2018年7月开始,尾线的数据收集于2018年10月开始。对照组在ANC访问期间接受医疗保健系统提供的标准护理。效应测量研究采用对数二项模型估计次优饮食习惯危险因素的调整相对危险度及其95%置信区间(CI)。结果:研究结束时,干预组总体最佳饮食习惯为65.1%,对照组为34.9% (p< 0.001)。与对照组孕妇相比,接受干预的孕妇在饮食习惯中出现次优风险的可能性降低41.0% (ARR = 0.591, 95%CI: 0.510-0.686)。结论:本研究揭示了通过健康发展部队的行为改变沟通(BCC)在改善孕妇饮食习惯方面是有效的。因此,建议通过健康发展军开展母婴保健,以加强孕妇的饮食习惯。
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引用次数: 0
Peri-conceptional folic acid supplementation: A Cross-Sectional Study to Assess the Awareness, Knowledge, Use and Associated Factors Among Pregnant Women Attending Antenatal Care in Two Secondary Health Care Facilities, Southwest Region, Cameroon 围孕期补充叶酸:一项评估在喀麦隆西南地区两家二级卫生保健机构接受产前护理的孕妇的意识、知识、使用和相关因素的横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/ogr098
Confidence A. Alemajo, Gregory E. Halle-Ekane, Elvis A. Nkengasong, Emmanuel A. Asongalem
Background: Neural tube defects(NTDs) are among the most common birth defects, contributing to miscarriages, infant mortality, severe congenital abnormalities, and serious disabilities. The protective effect of peri-conceptional folic acid (PFA) supplementation in reducing the risk of NTDs and other adverse pregnancy outcomes has been scientifically confirmed. Methods: A cross-sectional study was conducted using a structured questionnaire administered to 393 pregnant women seeking routine antenatal care between February to April 2020. Multivariate logistic regression was used to model factors associated with awareness, knowledge, and use of PFA. Results: Approximately 55% of women reported that they had heard of folic acid and only 6.1% had knowledge of folic acid (its benefit in preventing birth defects and the appropriate time to start using it). However, only 5.1% reported that they started using folic acid before pregnancy. Folic acid awareness showed a significant relationship with university education and above (OR=4.30, 95% CI [2.60, 7.30], P<0.001). There was also a significant difference in the odds of knowledge among those with a university education and above (OR=5.06, 95% CI [1.65, 19.0], P=0.0076). There was a statistically significant difference in the odds of awareness and knowledge of folic acid among women who had a history of folic acid education from a healthcare provider before pregnancy compared to those who did not, (OR=23.7, 95% CI [4.84, 430], P=0.002), (OR=12.0, 95% CI [4.31, 35.1], P<0.001) respectively. Even though women who planned their pregnancy (OR=4.89,
背景:神经管缺陷(NTDs)是最常见的出生缺陷之一,可导致流产、婴儿死亡、严重先天性异常和严重残疾。围孕期补充叶酸(PFA)在降低NTDs风险和其他不良妊娠结局方面的保护作用已得到科学证实。方法:采用结构化问卷对2020年2月至4月期间寻求常规产前保健的393名孕妇进行横断面研究。多变量逻辑回归用于模拟与PFA的意识、知识和使用相关的因素。结果:大约55%的女性报告说她们听说过叶酸,只有6.1%的女性了解叶酸(它在预防出生缺陷和开始使用叶酸的适当时间方面的好处)。然而,只有5.1%的人报告说她们在怀孕前开始服用叶酸。叶酸意识与大学及以上教育程度有显著关系(OR=4.30, 95% CI [2.60, 7.30], P<0.001)。大学及以上学历人群的知识知晓率也存在显著差异(OR=5.06, 95% CI [1.65, 19.0], P=0.0076)。怀孕前接受过医疗保健提供者叶酸教育的妇女与未接受过医疗保健提供者叶酸教育的妇女相比,对叶酸的认识和知识的几率有统计学意义的差异(OR=23.7, 95% CI [4.84, 430], P=0.002), OR=12.0, 95% CI [4.31, 35.1], P<0.001)。即使计划怀孕的女性(OR=4.89),
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引用次数: 1
Effect of Prophylactic Ondansetron on the Incidence of Spinal Anesthesia-Induced Shivering and Hypotension in Elective Cesarean Sections:Double-Blind, Placebo-Controlled, Randomized Clinical Trial 预防性昂丹司琼对选择性剖宫产术中脊麻引起的颤抖和低血压发生率的影响:双盲、安慰剂对照、随机临床试验
Pub Date : 2021-05-26 DOI: 10.21203/RS.3.RS-498935/V1
A. Salahat, Taha Aa, N. Almasri, E. Sweity
Background: Spinal anesthesia is the preferred method of anesthesia for caesarean section; however, it is associated with dangerous adverse effects on both mother and fetus, this includes: spinal anesthesia induced shivering and hypotension. Previous studies suggest serotonin may have a role in hypotension, bradycardia, and shivering occurrence perioeratively. In this prospective double-blind randomized control trial study, we evaluated the efficacy of the ondansetron, a serotonin receptor antagonist, on the incidence of spinal anesthesia-induced shivering, hypotension, nausea, vomiting and other possible complications in elective caesarean sections. This study conducted in Palestine, West Bank, Nablus city in the caesarean section operation rooms, and post-anesthesia care unit at Rafidia governmental hospital. Eighty full-term elective caesarean section parturient (Age 18-50 years) with ASA 1 or 2 classification were recruited and randomly allocated into two groups: prophylactic IV ondansetron treatment group and placebo 0.9% saline control group. The primary outcomes were the incidence of spinal anesthesia-induced shivering and hypotension, while secondary outcomes were perioperative bradycardia, nausea, vomiting, headache, pain, pruritus, dizziness and respiratory depression and parturient satisfaction. Results: Incidence of intraoperative hypotension and dizziness in the ondansetron group was significantly lower than which occurred in the control group (22.5% vs. 62.5% respectively; P < 0.001), the incidences and intensity of intraoperative shivering in the ondansetron group was lower than the control group (12.5 % vs. 32.5 % respectively; P = 0.032), Intraoperative nausea intensity in the ondansetron group was lower than control group (P = 0.049). Postoperatively, the incidence of postoperative dizziness in the ondansetron group was lower than the control group (5% vs. 37.5 % respectively; P = 0.001), the incidence and intensity of postoperative shivering in the ondansetron group was lower than the control group (12.5% vs. 37.5 % respectively; P = 0.01). Incidence and intensity of postoperative nausea in the ondansetron group was lower than the control group (17.5% vs. 40 % respectively; P = 0.026), the incidence of postoperative vomiting in the ondansetron group was lower than the control group (25.5% vs. 2.5 % respectively; P = 0.014).Conclusion: Prophylactic 4 mg IV ondansetron can significantly attenuate the incidences of spinal anesthesia-induced shivering and hypotension, dizziness, nausea, and vomiting occurrence and increase parturient satisfaction scale for parturient who undergo caesarean section.
背景:脊柱麻醉是剖宫产手术的首选麻醉方法;然而,它对母亲和胎儿都有危险的副作用,包括:脊髓麻醉引起的颤抖和低血压。先前的研究表明,血清素可能在低血压、心动过缓和颤抖中发挥作用。在这项前瞻性双盲随机对照试验研究中,我们评估了5-羟色胺受体拮抗剂昂丹司琼对选择性剖腹产中脊麻诱导的颤抖、低血压、恶心、呕吐和其他可能并发症发生率的疗效。本研究在巴勒斯坦、约旦河西岸、纳布卢斯市拉菲迪亚政府医院的剖腹产手术室和麻醉后护理室进行。招募80名ASA 1或2分类的足月选择性剖腹产产妇(年龄18-50岁),并将其随机分为两组:预防性静脉注射昂丹司琼治疗组和安慰剂0.9%生理盐水对照组。主要结果是脊麻引起的颤抖和低血压的发生率,而次要结果是围手术期心动过缓、恶心、呕吐、头痛、疼痛、瘙痒、头晕和呼吸抑制以及产妇满意度。结果:昂丹司琼组术中低血压和头晕的发生率显著低于对照组(分别为22.5%和62.5%;P<0.001),昂丹司琼组术中恶心强度低于对照组(P=0.049),昂丹司琼组术后寒战发生率和强度低于对照组(分别为12.5%和37.5%;P=0.01),昂丹司琼组术后呕吐发生率低于对照组(分别为25.5%和2.5%;P=0.014),剖宫产产妇的呕吐发生率和提高产妇满意度。
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引用次数: 1
A Triad Study in South Indian Population of Telangana: On the Association of Cytokine Gene Polymorphisms in the Aetiology of Spontaneous Abortions 南印度特伦甘纳人口的三合一研究:细胞因子基因多态性与自然流产病因的关系
Pub Date : 2021-01-01 DOI: 10.26502/ogr071
Renjini Devi MR, Shehnaz Sultana, V. M, Rambabu Sp, P. Nallari, Venkateshwari A
Background: Spontaneous abortion is defined as the loss of two or more consecutive pregnancies before 20 week of gestation. About 50% of the cases are remained with unexplained etiology. Potential immune cell differentiation and cytokine profile is detrimental for fetal-maternal communication and maternal recognition of pregnancy. An imbalance in the immune modulatory profile results in consecutive loss of pregnancies. In view of the above, the present study is taken up to understand the role of immunemodulators and their gene polymorphism in the etiology of spontaneous abortion. Methods: In the present case-control triad study genotyping for IFN γ+874 T/A, IL6-137 G/C, IL18174G/C polymorphisms were done by Amplified Refractory Mutation System polymerase chain reaction method (ARMS-PCR) and statistically analyzed. Result: A retrospective analysis for association of gene polymorphisms in the present study showed that Obstet Gynecol Res 2021; 4 (4): 220-232 DOI: 10.26502/ogr071 Obstetrics and Gynecology Research Vol. 4 No. 4– December 2021. 221 maternal and fetal TT genotype of IFN γ+874 polymorphism showed a twofold increased risk (OR 2.22, 95%CI= 1.29-3.84, p=0.004) whereas in IL 18 174G/C gene polymorphism and their association study, the case mother subjects that represented CC genotypes contributed a onefold increased risk towards the development of spontaneous abortion. (OR -2.17, 95%CI1.250-3.788, p=0.005) Conclusion: The proinflammatory and anti-inflammatory gene polymorphisms may contribute towards the susceptibility for spontaneous abortion.
背景:自然流产是指在妊娠20周之前连续两次或两次以上流产。约50%的病例病因不明。潜在的免疫细胞分化和细胞因子谱不利于胎儿与母体的沟通和母体对妊娠的识别。免疫调节谱的不平衡导致连续流产。鉴于上述,本研究旨在了解免疫调节剂及其基因多态性在自然流产病因学中的作用。方法:采用扩增难解突变系统聚合酶链反应法(ARMS-PCR)对IFN γ+874 T/A、IL6-137 G/C、IL18174G/C多态性进行基因分型,并进行统计学分析。结果:对本研究中基因多态性相关性的回顾性分析显示,《妇产科杂志》2021;4 (4): 220-232 DOI: 10.26502/ogr071妇产科研究卷4 No. 4 - 2021年12月。221母胎TT基因型IFN γ+874多态性增加了2倍的风险(OR 2.22, 95%CI= 1.29-3.84, p=0.004),而在IL 18 174G/C基因多态性及其相关性研究中,CC基因型的病例母亲受试者发生自然流产的风险增加了1倍。(OR -2.17, 95%CI1.250-3.788, p=0.005)结论:促炎和抗炎基因多态性可能与自然流产易感性有关。
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引用次数: 0
Twelve-Month outcomes of a Cluster-Randomized Trial of Home-Based Postpartum Contraceptive Delivery in Southwest Trifinio, Guatemala. 危地马拉特里菲尼奥西南部一项基于家庭产后避孕的12个月随机分组试验的结果
Pub Date : 2021-01-01 Epub Date: 2021-04-15 DOI: 10.26502/ogr057
Margo S Harrison, Saskia Bunge-Montes, Claudia Rivera, Andrea Jimenez-Zambrano, Gretchen Heinrichs, Antonio Bolanos, Edwin Asturias, Stephen Berman, Jeanelle Sheeder

Design: We executed a cluster-randomized parallel arm pragmatic trial to observe the association of home-based postpartum contraceptive provision, including the contraceptive implant, with three and 12-month contraceptive utilization, satisfaction, and pregnancy rates.

Methods: Eight clusters were randomized to receive either the home-based contraceptive delivery (condoms, pills, injection, implant) during the routine 40-day postpartum visit in addition to routine care, or routine care alone, which included comprehensive contraceptive counseling throughout antepartum care.

Results: 208 women were enrolled in the study, 108 in the intervention clusters and 100 in control clusters. 94 (87.0%) women in the intervention group and 91 (91%) of women in control clusters were evaluated 12 months post-enrollment. Likelihood of using contraception at that time was borderline increased in intervention clusters (RR 1.1 [1.0,1.3], p = 0.05) with an increased likelihood of long-acting contraceptive use (the implant; RR 1.6 [1.3,1.9], p < 0.001). Pregnancy rates were also borderline reduced in the intervention clusters (RR 1.0 [1.0,1.1], p = 0.07). There was no difference in satisfaction of women with contraceptive use between arms with about 95% of women very satisfied or a little satisfied in each arm. Continuation rates at twelve months of contraceptives in the intervention group were 0.0% for condom users, 80.0% for contraceptive pill users, 57% for injectable users, and 83% for implant users. Most women who discontinued their initial method chose a more long-term or permanent method. There was a trend toward a significant association with reduced short interval pregnancy.

Conclusion: Our study had a borderline increase in overall use of contraception by 12 months, did have an increased likelihood of long-acting contraceptive use of the implant by 12 months, and resulted in a trend toward reduced short interval pregnancy in the intervention clusters as compared to control clusters.

设计:我们执行了一项集群随机平行臂实用试验,观察以家庭为基础的产后避孕提供,包括避孕植入物,与3个月和12个月的避孕使用、满意度和妊娠率的关系。方法:8组患者随机分为两组,一组在产后40天的常规随访中,在常规护理的基础上进行家庭避孕(避孕套、避孕丸、注射、植入物),另一组接受常规护理,其中包括产前护理期间的综合避孕咨询。结果:208名妇女参加了研究,干预组108名,对照组100名。干预组94名(87.0%)妇女和对照组91名(91%)妇女在入组12个月后接受评估。当时使用避孕措施的可能性在干预组中呈边缘性增加(RR 1.1 [1.0,1.3], p = 0.05),使用长效避孕措施的可能性增加(植入物;RR为1.6 [1.3,1.9],p < 0.001)。干预组的妊娠率也有降低(RR为1.0 [1.0,1.1],p = 0.07)。两组妇女对避孕药具使用的满意度没有差异,每组约有95%的妇女非常满意或比较满意。在干预组中,安全套使用者的12个月避孕持续率为0.0%,避孕药使用者为80.0%,注射剂使用者为57%,植入物使用者为83%。大多数停止了最初方法的妇女选择了更长期或永久的方法。这一趋势与短间隔妊娠的减少有显著的关联。结论:我们的研究发现,在12个月的时间里,避孕药具的总体使用有一个边缘性的增加,在12个月的时间里,植入物使用长效避孕药具的可能性确实有增加,并且与对照组相比,干预组的短间隔妊娠有减少的趋势。
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引用次数: 0
Wound Care Education for Caesarean Section Clients: What Do Midwifery Students Know? 剖宫产病人的伤口护理教育:助产学学生知道些什么?
Pub Date : 2021-01-01 DOI: 10.26502/ogr067
Angelina Abban Ansu
Background: Complications associated with Caesarean Section (CS) delivery such as surgical site infection (SSIs) are complex. Infection of the CS wound has enormous consequences. A major risk factor associated with CS wound infection is lack of knowledge of CS clients about wound care. The knowledge of trainee midwives is critical if they are to educate CS clients on wound care. Aim: The objective of the study was to explore midwifery students’ knowledge on the education of CS clients on wound care. Materials and methods: This cross-sectional study purposely used 339 final year midwifery students within the Midwifery Training Colleges of Greater Accra Region. Participants answered a questionnaire formulated from relevant literature. Frequencies and percentages analyses were used for the data. Statistical analysis: Stata SE version 13 software. Results: This study revealed that 317 (93.1%), 325 (96%), 320 (94.4%) were knowledgeable about CS, surgical site wound care and education for CS clients on wound care respectively. Again, 286 (84.37%) of the students indicated that their training has equipped them to give education on wound care to CS clients. However, 227 (65.96%), 287 (84.66%), 179 (52.8%) did not have adequate knowledge on aspects of indications for CS delivery, surgical site wound care and education for CS client on wound care, respectively. Conclusions: Majority of the final year midwifery students recorded higher knowledge scores about CS, surgical site wound care and education for CS clients on surgical site wound care. However, quite a number could not respond to aspects of indication for CS delivery and CS wound care.
背景:与剖宫产(CS)相关的并发症,如手术部位感染(ssi)是复杂的。CS伤口感染的后果非常严重。与CS伤口感染相关的一个主要危险因素是CS患者缺乏伤口护理知识。见习助产士的知识是至关重要的,如果他们要教育CS客户的伤口护理。目的:探讨助产学学生对CS客户伤口护理教育的认知情况。材料和方法:这项横断面研究专门使用了大阿克拉地区助产培训学院的339名助产学最后一年的学生。参与者回答了一份根据相关文献制定的问卷。数据采用频率和百分比分析。统计分析:Stata SE版本13软件。结果:317名(93.1%)、325名(96%)、320名(94.4%)分别对CS、手术部位伤口护理和CS患者伤口护理知识有所了解。同样,286名(84.37%)学生表示,他们的培训使他们具备向CS客户提供伤口护理教育的能力。然而,227名(65.96%)、287名(84.66%)、179名(52.8%)对CS分娩指征、手术部位伤口护理和CS病人伤口护理教育方面的知识不足。结论:大多数助产学最后一年的学生对CS、手术部位伤口护理和CS客户手术部位伤口护理的知识得分较高。然而,相当多的患者在CS分娩和CS伤口护理的适应证方面没有反应。
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引用次数: 0
Frequency and Risk Factors for Depression and Anxiety in Patients with Polycystic Ovary Syndrome Presenting in a Tertiary Care Hospital Karachi, Pakistan 巴基斯坦卡拉奇三级医院多囊卵巢综合征患者抑郁和焦虑的频率和危险因素
Pub Date : 2021-01-01 DOI: 10.26502/ogr068
A. Tariq, Manahil Tariq Malik, H. Tariq, Samina Naseem khattak, T. Yazdani, Rameen Tariq Malik, S. Rauf, T. Malik
Objective: To determine the frequency and risk factors for depression and anxiety in patients with Poly cystic ovary syndrome (PCOS). Study design: Comparative Analytic Study. Setting and duration: Department of Obstetrics and Gynaecology at a tertiary care hospital in Karachi, Pakistan from July 2020-December 2020. Materials and methods: All females with diagnosed PCOS aged between 15-45yrs were included in the study .A total of 270 females (n=135) formed the study group. Group A (n=135) constituted females diagnosed to have PCOS and group B (n=135) without PCOS. Obstet Gynecol Res 2021; 4 (4): 196-202 DOI: 10.26502/ogr068 Obstetrics and Gynecology Research Vol. 4 No. 4– December 2021. 197 Both groups were compared for anxiety and depression according to Hospital anxiety and Depression Scale (HADS).Demographic features were compared as well (age, qualification, BMI and parity). Results: A total of 270 females were part of this research (n=135).Most 170 (62.9%) of study population was aged between 21-35years.112 (41.5%) were undergraduate .Most 160 (59.2%) of participants had normal BMI <25kg/m .In group A, 38 (28.1%) had depression along with 43(31.9%) having borderline depression versus 12 (8.9%) had borderline depression in group B, p-value 0.000, which is statistically significant .The overall incidence of anxiety in Group A was 116 (85.9%) versus 50 (37%), p value 0.00 which is statistically significant. Conclusion: Depression and anxiety are common in PCOS. There is strong association of depression with young age (21-35), among graduate women and with no children that is subfertility.
目的:了解多囊卵巢综合征(PCOS)患者抑郁、焦虑的发生频率及其危险因素。研究设计:比较分析研究。地点和时间:2020年7月至2020年12月在巴基斯坦卡拉奇一家三级保健医院的妇产科。材料与方法:所有年龄在15-45岁之间诊断为PCOS的女性纳入研究,共270名女性(n=135)组成研究组。A组(n=135)为诊断为PCOS的女性,B组(n=135)为未诊断为PCOS的女性。妇产科杂志2021;4 (4): 196-202 DOI: 10.26502/ogr068妇产科研究卷4第4期- 2021年12月。197根据医院焦虑抑郁量表(HADS)比较两组的焦虑和抑郁。还比较了人口统计学特征(年龄、资格、BMI和性别平等)。结果:共有270名女性参与了本研究(n=135)。研究人群中年龄在21-35岁之间的170人(62.9%)最多A组有抑郁38人(28.1%),边缘性抑郁43人(31.9%),B组有边缘性抑郁12人(8.9%),p值0.000,差异有统计学意义。A组总焦虑发生率116人(85.9%)比50人(37%),p值0.00,差异有统计学意义。结论:PCOS患者普遍存在抑郁和焦虑。抑郁症与年轻(21-35岁)、大学毕业的女性和没有孩子的低生育能力有很强的联系。
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引用次数: 1
Characteristics Associated with Choosing Long-Acting Reversible Contraception in Rural Guatemala: A Secondary Analysis of a Cluster-Randomized Trial. 危地马拉农村选择长效可逆避孕措施的相关特征:一项集群随机试验的二次分析。
Pub Date : 2021-01-01 Epub Date: 2021-06-25 DOI: 10.26502/ogr062
Margo S Harrison, Saskia Bunge-Montes, Claudia Rivera, Andrea Jimenez-Zambrano, Gretchen Heinrichs, Antonio Bolanos, Edwin Asturias, Stephen Berman, Jeanelle Sheeder

Design: We conducted a secondary analysis of a cluster-randomized trial to observe characteristics associated with women who chose to use long-acting reversible contraceptives (LARC) compared to those who chose a short-acting method 12 months after enrollment.

Methods: The trial studied four control and four intervention clusters where the intervention clusters were offered contraception at their 40-day routine postpartum visit; control clusters received standard care, which included comprehensive postpartum contraceptive counseling. Women were followed through twelve months postpartum.

Results: The study enrolled 208 women; 94 (87.0%) were in the intervention group and 91 (91.0%) were in the control group. At twelve months, with 130 (70.3%) women using contraception at that time. 94 women (50.8%) were using a short acting method compared to 33 (17.9%) who chose a long-acting method, irrespective of cluster. In mixed effect regression modeling adjusted for cluster, characteristics associated with a reduced likelihood of choosing long-acting contraception in multivariate modeling included age (aRR 0.98 [0.96,0.99], p = 0.008) and any education (compared to no education; aRR 0.76 [0.60,0.95], p = 0.02). Women who were sexually active by their enrollment visit (40 days postpartum) were 30% more likely to opt for a long-acting method (aRR 1.30 [1.03,1.63], p = 0.03).

Conclusion: Older and more educated women were less likely to be using LARC a year after enrollment, while women with a history of early postpartum sexual activity were more likely to choose LARC.

设计:我们对一项集群随机试验进行了二次分析,以观察选择长效可逆避孕药(LARC)的妇女与选择短效避孕药的妇女在入组12个月后的相关特征。方法:研究了4个对照组和4个干预组,干预组在产后40天的常规随访中给予避孕措施;对照组接受标准护理,包括全面的产后避孕咨询。这些妇女在产后12个月被跟踪调查。结果:该研究招募了208名女性;干预组94例(87.0%),对照组91例(91.0%)。在12个月时,当时有130名(70.3%)妇女使用避孕措施。94名妇女(50.8%)使用短效方法,而33名妇女(17.9%)选择长效方法,无论分组如何。在经聚类调整的混合效应回归模型中,与多变量模型中选择长效避孕方法可能性降低相关的特征包括年龄(aRR为0.98 [0.96,0.99],p = 0.008)和任何教育程度(与无教育程度相比;aRR为0.76 [0.60,0.95],p = 0.02)。在入组时(产后40天)性活跃的妇女选择长效方法的可能性高出30% (aRR 1.30 [1.03,1.63], p = 0.03)。结论:年龄较大和受教育程度较高的妇女在入组一年后较少使用LARC,而有产后早期性行为史的妇女更有可能选择LARC。
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引用次数: 0
Pregnancy outcomes at Mizan-Tepi University Teaching Hospital: A Comparison to the Ethiopian Demographic and Health Surveys. 米赞-特皮大学教学医院的妊娠结局:与埃塞俄比亚人口和健康调查的比较
Pub Date : 2021-01-01 Epub Date: 2021-04-14 DOI: 10.26502/ogr056
Margo Shawn Harrison, Margaret Muldrow, Ephrem Kirub, Tewodros Liyew, Biruk Teshome, Andrea Jimenez-Zambrano, Teklemariam Yarinbab

Background: To compare outcomes at Mizan-Tepi University Teaching Hospital to national and regional data and to plan quality improvement and research studies based on the results.

Methods: This study was a prospective hospital-based cross-sectional analysis of a convenience sample of 1, 000 women who delivered at Mizan-Tepi University Teaching Hospital.

Results: Our convenience sample was young (median age 24 years) with a primarily school level or less of education (68.6%). Only about 5% of women had a history of prior cesarean birth, 2.1% reported they were human immunodeficiency virus seropositive, and the median number of prenatal visits was four. Women were commonly admitted in spontaneous labor (84.5%), transferred from another facility (49.2%; 96.8% of which were referred from a health center), and had their fetal heart rate auscultated on admission (94.7%). Only 5.2% of women did not deliver within twenty-four hours and the cesarean birth prevalence was 23.4%. Many women were delivered by midwives (73.2%; all unassisted vaginal births), 89.2% were term deliveries, and 92.5% of neonatal birthweights were 2500 grams or heavier. Less than five percent of women delivered stillbirths (4.3%) and 5.7% of livebirths experienced neonatal death by the day of discharge. There were no maternal deaths in the cohort.

Conclusion: The prevalence of stillbirth and neonatal death were the most notable findings, while there was no maternal death in the cohort.

背景:将米赞特皮大学教学医院的结果与国家和地区数据进行比较,并根据结果计划质量改进和研究。方法:本研究是对在米赞特皮大学教学医院分娩的1000名妇女进行前瞻性的基于医院的横断面分析。结果:我们的方便样本很年轻(中位年龄24岁),受教育程度在初级学校或以下(68.6%)。只有约5%的妇女有剖宫产史,2.1%的妇女报告他们是人类免疫缺陷病毒血清阳性,产前检查的中位数为4次。妇女通常是自然分娩入院(84.5%),从其他机构转移过来(49.2%;其中96.8%是从健康中心转介的),并在入院时听诊胎儿心率(94.7%)。只有5.2%的妇女没有在24小时内分娩,剖宫产率为23.4%。许多妇女由助产士接生(73.2%;89.2%为足月分娩,92.5%的新生儿出生体重为2500克或更重。不到5%的死产妇女(4.3%)和5.7%的活产妇女在出院当天经历了新生儿死亡。该队列中没有产妇死亡。结论:死产和新生儿死亡的发生率是最显著的发现,而队列中没有产妇死亡。
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引用次数: 2
Role of Endometrial Scratching in Implantation Failures 子宫内膜划伤在着床失败中的作用
Pub Date : 2021-01-01 DOI: 10.26502/ogr070
K. Banerjee, B. Singla
Objective: To assess the role of endometrial scratching in implantation failure cases. Design: Retrospective analysis. Materials and Methods: 60 infertile females with at least one IVF failure in the age group of 23 to 35 years were evaluated in a period of 6 months. In the group 1 of 30 females, endometrial scratching was done between Day 21 to 25 of previous periods and in the group 2 of 30 females, endometrial scratching was not done. Controlled ovarian stimulation (COH) was started from day 2 of next period in all subjects with the antagonist protocol. Transvaginal guided oocyte aspiration was done. Day 3 embryo transfer was performed in all subjects. Results: There was no difference between the two groups regarding demographic variables, egg reserve, sperm parameters, number of embryos transferred and embryo quality. The pregnancy rate was 40% (12 out of 30 cases) in the group 1 that was similar to 36.7% in the group 2 (11 out of 30 cases). The clinical pregnancy rate was 36.7% (11 out of 30 cases) in the group 1 that was similar to 33.3% in the group 2 (10 out of 30 cases). Conclusions: The local injury caused by endometrial scratching though result in local inflammation and angiogenic environment in uterus but it does not improve the pregnancy rate. Further studies are needed to prove the efficacy of endometrial scratching with larger sample size. This is one of the few studies done in South Asia that showed scratching has no role in implantation failure.
目的:探讨子宫内膜抓挠在子宫着床失败中的作用。设计:回顾性分析。材料与方法:对年龄在23 ~ 35岁的60例至少有一次IVF失败的不孕女性进行为期6个月的评估。在第一组(30名女性)中,在前一次月经的第21天至第25天之间进行子宫内膜抓挠,而在第二组(30名女性)中,不进行子宫内膜抓挠。所有使用拮抗剂方案的受试者从下一个周期的第2天开始进行控制性卵巢刺激(COH)。经阴道引导卵母细胞抽吸。所有受试者均在第3天进行胚胎移植。结果:两组在人口学变量、卵子储备、精子参数、移植胚胎数量和胚胎质量方面均无差异。1组妊娠率为40%(30例中有12例),2组为36.7%(30例中有11例)。1组临床妊娠率为36.7%(30例中11例),2组临床妊娠率为33.3%(30例中10例)。结论:子宫内膜刮伤引起的局部损伤可引起子宫局部炎症和血管生成环境,但不能提高妊娠率。进一步的研究需要更大的样本量来证明子宫内膜刮擦的有效性。这是在南亚进行的少数几项研究之一,该研究表明抓挠与植入失败无关。
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引用次数: 0
期刊
Obstetrics and gynecology research
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