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In Order to Find Endometrial Disease in Peri- and Post-menopausal Hemorrhage, Hysteroscopy, Ultrasonography, and Histopathology Were Compared 为了发现围绝经期和绝经后出血的子宫内膜疾病,我们比较了宫腔镜、超声检查和组织病理学检查
Pub Date : 2023-01-01 DOI: 10.26502/ogr0114
Jihad M. Al Hasan, Kawsar Diab, K. Ghazal
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引用次数: 0
Prevalence and Predictors of Low Birth Weight in a Rural Guatemalan Community. 危地马拉农村社区出生体重不足的发生率和预测因素。
Pub Date : 2022-03-01 Epub Date: 2022-01-03 DOI: 10.26502/ogr073
Emily S Himes, Claudia Rivera, Amy S Nacht, Saskia Bunge-Montes, Andrea Jimenez-Zambrano, Gretchen Heinrichs, Antonio Bolanos, Edwin Asturias, Stephen Berman, Margo S Harrison

Background: The intention of our study was to establish the prevalence of low birth weight (LBW) as well as risk factors for LBW in infants born to a convenience sample of women enrolled in a home visitation maternal care program associated with the Center for Human Development in Southwest Trifinio, Guatemala.

Methods: This is an observational study analyzing self-reported data from a quality improvement database. We recorded the distribution of birthweights of infants born to women enrolled in Madres Sanas that delivered between October 2018 and December 2019. We grouped women by LBW (<2500g ) and adequate birthweight (≥2500g) infants, and performed bivariate comparisons using sociodemographic, obstetric, and intrapartum data. Using the independent variables shown to have an association with LBW, we then performed a multivariable analysis.

Results: There were 226 births among our program participants, 218 with recorded birthweights. The median birthweight was 3175g; 13.8% were LBW (<2500g), higher than Guatemala's average of 10.9%. Through our bivariate analysis, we determined women with LBW infants were younger, with a median age of 20.8 (IQR [17.8-23.7]) compared to a median age of 23.2 (IQR [19.8-27.3]) among women with infants ≥2500g (P=0.03). Women with LBW infants were also more likely to have fewer than 4 prenatal visits (33.3% vs 19.3%, P=0.04).

Conclusion: Two significant findings emerged from our analysis: LBW infants were more commonly born to women who were younger in age and who had received fewer than 4 prenatal visits. These findings are consistent with existing literature on LBW in Latin America. Our study helps to strengthen the data around these associations and gives credence to programming and policy efforts in Latin America that support adequate prenatal care for all and youth education about reproductive health and contraceptive access.

研究背景我们的研究旨在确定危地马拉特里菲尼奥西南部人类发展中心家访孕产妇护理项目的方便抽样妇女所生婴儿中低出生体重儿(LBW)的患病率以及导致低出生体重儿的风险因素:这是一项观察性研究,分析的是质量改进数据库中的自我报告数据。我们记录了 2018 年 10 月至 2019 年 12 月期间参加 Madres Sanas 的妇女所生婴儿的出生体重分布情况。我们按照低体重儿对妇女进行了分组(结果:我们的计划参与者中共有 226 名新生儿,其中 218 名记录了出生体重。出生体重中位数为 3175 克;13.8% 为低体重儿(P=0.03)。产前检查次数少于 4 次的低体重儿妇女的比例也更高(33.3% vs 19.3%,P=0.04):我们的分析有两个重要发现:结论:我们的分析得出了两个重要发现:年龄较小、产前检查次数少于 4 次的产妇更容易生出枸杞婴儿。这些发现与拉丁美洲有关低体重儿的现有文献一致。我们的研究有助于加强有关这些关联的数据,并为拉丁美洲的计划和政策工作提供了依据,这些工作支持为所有人提供充分的产前保健,并为青少年提供有关生殖健康和避孕药具的教育。
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引用次数: 0
Quality of Life of Women after Mastectomy in Two Training Hospitals in the City of Douala, Cameroon 喀麦隆杜阿拉市两家培训医院乳房切除术后妇女的生活质量
Pub Date : 2022-01-01 DOI: 10.26502/ogr075
Charlotte Nguefack Tchente, Jean Paul Ndamba Engbang, Christian Eyoum, M. Kamdem, Lucie Sorelle Lekuikeu Tchuinte, Albertine Eloundou, H. Essome, M. Ekono, Pierre Marie Tebeu, E. Mboudou
Introduction: Breast cancer is the most common cancer in women worldwide. In Cameroon, several women with breast cancer have gone through mastectomy for treatment. They face some difficulties living in society and within their couple with Obstet Gynecol Res 2022; 5 (1): 020-033 DOI: 10.26502/ogr075 Obstetrics and Gynecology Research Vol. 5 No. 1– March 2022. 21 only one breast. The aim of this study was to describe the quality of life (QOL) of women after mastectomy in two hospitals in Douala. Methods: This was a cross-sectional study carried out in two healthcare facilities over 4 months. Data from 102 consenting patients with unilateral mastectomy was collected. A survey sheet was used to collect patient socio-demographic, clinical, therapeutic data and data on QOL. We evaluated the QOL using questions from the various recognized questionnaires (EORTC QLQ-BR45, WHOQOL-BREF, FACT-MBIS and FACT-B) which we adapted according to our context. Chi-squared and Fisher tests allowed us to assess the association between variables. Statistical significance was set at p <0.05. Results: The mean age at mastectomy was 48.2 ± 10years and 54.4% were married. Clinically, patients with a tumor size more than 5cm and inflammatory tumors were most represented (76.3%); 89.1% had lymph node involvement and 16.1% were metastatic at diagnosis. Other treatments received include chemotherapy (93%), radiotherapy (32.3%) and hormone therapy (22.1%). The overall QOL was impaired. Using a mean score on a scale of 0 to 4, physical (0.3), social (0.5), and sexual (1.2) QOL were less impaired than emotional (1.5), functional (2.7), and psychological (3) QOL. Factors associated with impaired physical QOL included young age (OR:6.11[2-18.58]; p:0.00007), being single (OR:3.1 [1.2-7.7]; p:0.01), tumor size between 2 and 5cm (OR:4.97[2-12.4]; p:0.0002). Those associated with the deterioration in overall QOL included delayed diagnosis and mastectomy (OR:16.60[1.61-170.45]; p:0.008). Conclusion: The overall quality of life was impaired in all patients. Thus, patients undergoing mastectomy should benefit from preand postoperative psychological care.
乳腺癌是世界范围内女性最常见的癌症。在喀麦隆,几名患有乳腺癌的妇女接受了乳房切除术治疗。他们面临着一些困难,生活在社会和他们的夫妇与妇产科的2022;5 (1): 020-033 DOI: 10.26502/ogr075妇产科研究卷5第1号- 2022年3月。只有一个乳房。本研究的目的是描述杜阿拉两家医院乳房切除术后妇女的生活质量(QOL)。方法:这是一项在两家医疗机构进行的为期4个月的横断面研究。收集了102例同意单侧乳房切除术的患者的数据。采用调查表收集患者的社会人口学、临床、治疗资料和生活质量数据。我们使用各种公认的问卷(EORTC QLQ-BR45, WHOQOL-BREF, FACT-MBIS和FACT-B)中的问题来评估生活质量,我们根据我们的背景进行了调整。卡方检验和费雪检验使我们能够评估变量之间的关联。p <0.05为差异有统计学意义。结果:乳房切除术患者平均年龄为48.2±10岁,已婚患者占54.4%。临床以肿瘤大小大于5cm及炎性肿瘤多见(76.3%);89.1%在诊断时有淋巴结累及,16.1%有转移。其他治疗包括化疗(93%)、放疗(32.3%)和激素治疗(22.1%)。总体生活质量下降。使用0到4的平均分数,身体(0.3),社会(0.5)和性(1.2)的生活质量比情感(1.5),功能(2.7)和心理(3)的生活质量受到的损害要小。与身体生活质量受损相关的因素包括年幼(OR:6.11[2-18.58];p:0.00007),单身(OR:3.1 [1.2-7.7];p:0.01),肿瘤大小在2 ~ 5cm之间(OR:4.97[2-12.4];p: 0.0002)。与总体生活质量恶化相关的因素包括延迟诊断和乳房切除术(OR:16.60[1.61-170.45];p: 0.008)。结论:所有患者的整体生活质量均受到影响。因此,接受乳房切除术的患者应受益于术前和术后的心理护理。
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引用次数: 0
Induction of Labor: A Comparison of Guidelines 引产指南的比较
Pub Date : 2022-01-01 DOI: 10.26502/ogr081
Muneera Ahmed Alkhalifa, S. Hsu, Nusiba ElHassan, Basma AlAnsari, Rehab Ismael, Gulmeen Raza, H. Malas, Mahmoud Samy Ismail
Introduction: Induction of labor (IOL) is a commonly performed obstetric procedure that initiates labor prior to its spontaneous onset. It is advised when the benefits of terminating the pregnancy outweigh the risks of ongoing pregnancy. Aim: This is a review article that compares the most recent international guidelines on IOL by organizations including World Health Organization (WHO), the National Institute for Health and Care Excellence (NICE), American College of Obstetricians and Gynecologists (ACOG), the Society of Obstetricians and Gynecologists of Canada (SOGC), the Federation of Obstetric and Gynecological Socie-ties of India (FOGSI) and Queensland Health. We will also compare these recommendations to the current guidelines set in our institute, King Hamad University Hospital (KHUH) in the Kingdom of Bahrain. Conclusion: The most notable differences were observed in the Bishop scoring with minor differences in Obstet Gynecol Res 2022; 5 (1): 081-106 DOI: 10.26502/ogr081 Obstetrics and Gynecology Research Vol. 5 No. 1– March 2022. 82 the methods of induction and management of complications. Improving KHUH guidelines in particular areas would enhance patient care. Regular audits are essential to ensure practice is consistent with the guidelines.
导言:引产(IOL)是一种常见的产科手术,在自然发生之前开始分娩。当终止妊娠的好处大于继续妊娠的风险时,建议终止妊娠。目的:这是一篇综述性文章,比较了包括世界卫生组织(WHO)、国家健康与护理卓越研究所(NICE)、美国妇产科学院(ACOG)、加拿大妇产科学会(SOGC)、印度妇产科学会联合会(FOGSI)和昆士兰卫生组织在内的组织关于IOL的最新国际指南。我们还将把这些建议与我们研究所——巴林王国哈马德国王大学医院(KHUH)制定的现行指导方针进行比较。结论:两组患者Bishop评分差异最显著,产科妇科评分差异较小;5 (1): 081-106 DOI: 10.26502/ogr081妇产科研究卷5第1号- 2022年3月。并发症的诱导和处理方法。改善特定领域的KHUH指南将加强患者护理。定期审计对于确保实践与指导方针一致至关重要。
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引用次数: 1
A Rare Finding of Clostridium Tertium in an Immunocompetent Patient Following Gynecological Surgery 一个罕见的发现,在免疫功能正常的病人妇科手术后的特氏梭菌
Pub Date : 2022-01-01 DOI: 10.26502/ogr084
Lauren Leightell-Brown, Alexander Frost-Younger, S. Rundle, C. Ang
Clostridium tertium (C. tertium) is a Gram-positive, aerotolerant bacillus and a rare human pathogen usually identified in neutropenic patients with hematological malignancy. Limited case reports in non-neutropenic patients suggest the C. tertium is a potential pathogen when associated with risk factors which include intestinal mucosal disruption and beta-lactam antibiotic use. Our case is a 59-year-old woman who developed a post-operative collection containing C.tertium following complete cytore-ductive surgery for high-grade serous cancer of tubo-ovarian origin in the absence of neutropenia. To our knowledge, this is the first documented case of C. tertium infection in a post-operative Gynecological-Oncology patient.
tertium梭菌(C. tertium)是一种革兰氏阳性的耐氧芽孢杆菌,是一种罕见的人类病原体,通常在嗜中性粒细胞减少的血液恶性肿瘤患者中发现。非中性粒细胞减少患者的有限病例报告表明,当与肠黏膜破坏和β -内酰胺类抗生素使用等危险因素相关时,C. tertium是一种潜在的病原体。我们的病例是一名59岁的女性,她在没有中性粒细胞减少的情况下,因输卵管卵巢起源的高级别浆液性癌进行了完全的细胞减少术,术后收集到含有c.t tium的标本。据我们所知,这是第一例记录在案的C. tertium感染在术后妇科肿瘤患者。
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引用次数: 0
Single Versus Multiple Dose of Antibiotic Prophylaxis in Caesarian Section: A Randomized Controlled Trial 剖腹产术中单剂量与多剂量抗生素预防:一项随机对照试验
Pub Date : 2022-01-01 DOI: 10.26502/ogr089
A. K, Partha Majumder S, S. R
Background: Single-dose prophylaxis, a type of prophylactic antibiotic, used in a caesarean section usually helps in lessening the growth of microorganism confrontation. Single-dose prophylaxis is a very short course of an antibiotic used just before the surgery begins which helps in the improvement of aseptic and surgical procedures and reduces postoperative wound infections more effectively than multiple doses of it. Methods: This study is a single-blinded single centred randomized control trial which was conducted at the Department of Obstetrics and Gynecology, in Shahed Suhrawardy Medical College Hospital. The study period for this trial was June 13- to November 13. The sample size for this study was 136. Result: In the study group most of the respondents 54(79.4%) were aged between 20-25 years wherein in the control group most of the respondents 54(79.4%) were aged between 20-25 years. In the control group, most of the operations 45(66%) had needed <30 minutes wherein in the control group most of the operations 55(80.9%) had needed <30 minutes. In the caesarean section of the study group, 13(19.1%) were routine patients while 44(64.7%) were emergency. On the other hand, in the caesarean section of the control group 13(19.1%) were routine patients while 55(80.9%) were emergency. The grade O wound infection of the study group was 54(79.4%) whereas the control group was 53(77.9%) and followed by grade I was 11(16.2%) in both groups, grade III in the study group was 3(4.4%), grade IV in the control group was 4(5.9%). Most of the respondents of the study group 48(70.7%) had stayed between 3-5 days after the operation and wherein the control group 55(80.9%) had stayed between 3-5 days after the operation. Conclusion: Single-dose antibiotic prophylaxis is equally effective and less costly than multi-dose in uncomplicated gynecology and obstetrics cases and can be instituted in our setting.
背景:单剂量预防是一种预防性抗生素,用于剖宫产通常有助于减少微生物对抗的生长。单剂量预防是在手术开始前使用的一种非常短的抗生素疗程,它有助于改善无菌和手术程序,比多次使用更有效地减少术后伤口感染。方法:本研究为单盲单中心随机对照试验,在Shahed Suhrawardy医学院附属医院妇产科进行。该试验的研究期为6月13日至11月13日。本研究的样本量为136人。结果:研究组54人(79.4%)年龄在20 ~ 25岁之间,对照组54人(79.4%)年龄在20 ~ 25岁之间。对照组45例(66%)手术时间<30分钟,对照组55例(80.9%)手术时间<30分钟。研究组剖宫产术中,常规13例(19.1%),急诊44例(64.7%)。对照组常规剖宫产13例(19.1%),急诊55例(80.9%)。研究组创面感染O级54例(79.4%),对照组53例(77.9%),两组创面感染I级11例(16.2%),研究组创面感染III级3例(4.4%),对照组创面感染IV级4例(5.9%)。研究组48例(70.7%)患者术后停留时间在3 ~ 5天,对照组55例(80.9%)患者术后停留时间在3 ~ 5天。结论:在无并发症的妇产科病例中,单剂量抗生素预防与多剂量抗生素预防同样有效且费用更低,可在我国推广应用。
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引用次数: 0
Retrospective evaluation of the impact of second-stage labor arrest on stress urine incontinence in postpartum women 第二产程骤停对产后应激性尿失禁影响的回顾性评价
Pub Date : 2022-01-01 DOI: 10.26502/ogr099
G. Yared, Jihad Al Hassan, C. Hajjar, K. Ghazal
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引用次数: 0
Costs associated with Female Urinary Incontinence: an integrative review of the literature 与女性尿失禁相关的费用:文献的综合回顾
Pub Date : 2022-01-01 DOI: 10.26502/ogr0107
Julieta Aránguiz-Ramírez, P. Olivares-Tirado, Xavier Castells-Oliveres
In women, the anatomical peculiarities of the pelvic floor and the risk factors for its dysfunction predispose women to suffer from Urinary Incontinence (UI), a condition that, although it does not pose a vital risk, negatively affects their quality of life and represents a high risk of the economic cost, still invisible. Objective: To describe the scientific evidence available regarding studies of costs associated with UI in women. Methods: Integrative review of the literature using the PubMed, Embase, ScienceDirect and Scopus databases as data sources, on studies of direct and indirect costs of UI. in women, published between 2009 and 2022. Using the search terms in Spanish and/or English: “Cost of illness”, “direct cost”, “indirect cost”, “urinary incontinence” and “woman”. The monetary values were adjusted from the date of the study to December 31,2021 and local currencies were converted to USD. Results: Of the 302 articles reviewed, 14 met the criteria for analysis. Some studies considered the estimate of the total economic burden including direct and indirect costs. The annual direct cost per capita ranges from US$ 153.71 to US$ 32,709 depending on the country, medication use and age, the indirect cost corresponds to an average 160 hours per year for presenteeism. Conclusion: In high-income countries, the economic burden for urinary incontinence is notorious, in Latin American and Caribbean countries there are no economic evaluations regarding it, to improve the benefits for women's health, it is advisable to update. Affiliation: aDoctoral Program in Biomedical Research Methodology and Public Health at the Department of Pediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health at the Autonomous University of Barcelona (UAB), Barcelona, Spain bAssistant teacher. Department of Obstetrics and Neonatology of Diego Portales University, Santiago, Chile cPublic Health Program, School of Public Health, Faculty of Medicine, University of Chile, Santiago, Chile dDepartment of Epidemiology and Evaluation, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. Autonomous University of Barcelona, Spain *Corresponding author: Julieta Aránguiz-Ramírez, Doctoral Program in Biomedical Research Methodology and Public Health at the Department of Pediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health at the Autonomous University of Barcelona (UAB), Barcelona, Spain. Citation: Julieta Aránguiz-Ramírez, Pedro OlivaresTirado, Xavier Castells-Oliveres. Costs associated with Female Urinary Incontinence: an integrative review of the literature. Obstetrics and Gynecology Research 5 (2022): 325-333. Received: December 11, 2022 Accepted: December 27, 2022 Published: December 30, 2022
在女性中,骨盆底的解剖特点及其功能障碍的危险因素使女性易患尿失禁(UI),这种情况虽然不构成重大风险,但会对她们的生活质量产生负面影响,并带来很高的经济成本风险,但仍然看不见。目的:描述有关女性尿失禁相关费用研究的现有科学证据。方法:以PubMed、Embase、ScienceDirect和Scopus数据库为数据源,对UI的直接和间接成本研究进行文献综述。女性,发表于2009年至2022年之间。用西班牙语和/或英语搜索关键词:“疾病成本”、“直接成本”、“间接成本”、“尿失禁”和“女性”。货币价值从研究日期调整到2021年12月31日,当地货币转换为美元。结果:302篇文献中,14篇符合分析标准。有些研究考虑了包括直接和间接费用在内的总经济负担的估计。根据国家、药物使用和年龄的不同,每年人均直接费用从153.71美元到32,709美元不等,间接费用相当于每年平均160小时的出勤。结论:在高收入国家,尿失禁的经济负担是臭名昭著的,在拉丁美洲和加勒比国家没有关于尿失禁的经济评价,为了提高对妇女健康的益处,建议更新。所属单位:西班牙巴塞罗那自治大学(UAB)儿科、妇产科、预防医学和公共卫生系生物医学研究方法和公共卫生博士课程助理教师。智利圣地亚哥圣地亚哥圣地亚哥大学医学院公共卫生学院公共卫生项目;西班牙巴塞罗那德尔马医院医学研究所流行病学与评价系。通讯作者:Julieta Aránguiz-Ramírez,西班牙巴塞罗那自治大学(UAB)儿科、妇产科、预防医学和公共卫生系生物医学研究方法和公共卫生博士课程。引用:Julieta Aránguiz-Ramírez, Pedro OlivaresTirado, Xavier castels - oliveres。与女性尿失禁相关的费用:文献的综合回顾。妇产科研究5(2022):325-333。收稿日期:2022年12月11日收稿日期:2022年12月27日发表日期:2022年12月30日
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引用次数: 0
Knowledge and Practice of Gestational Diabetes Mellitus Management Guideline among the Nurses of Tertiary Hospitals in Capital Bangladesh 孟加拉国首都三级医院护士对妊娠期糖尿病管理指南的了解与实践
Pub Date : 2022-01-01 DOI: 10.26502/ogr080
H. Khanom, B. Banu, Mir Rabiul Islam, K. Khanom, Sujana Haque Chowdhury, S. Hossain
Background: Gestational Diabetes Mellitus (GDM) accounts for the majority of cases of diabetes compli-cating pregnancy. This study aimed to delineate the levels of knowledge and practice about GDM management among the nurses of Dhaka, Bangladesh. Method: This cross-sectional study was conducted among 427 nurses of three healthcare centers of Dhaka city. Data were collected by semi-structured questionnaire through face-to-face interview. All data were analyzed through descriptive and inferential statistical techniques. Knowledge and practice scores were categorized as poor (Mean+1SD) by predefined scores. Result: In this present study, mean age of the respon-Obstet dents was found 27.8 ± 5.5, and level of knowledge (both basic and technical knowledge) was found to be average where basic knowledge was 66.3% and technical knowledge was 67%. Female nurses had better basic knowledge and practice regar-ding GDM, compared to their counterparts (p=0.002). There was a significant association with the respon-dent’s gender, level of education and workplace with the basic knowledge regarding GDM management. There was a significant association with the level of education and marital status of respondents with technical knowledge and regarding proper GDM management practice only monthly family income of respondent’s shows significant association. Conclusion: The results revealed that there is a gap of knowledge and practice about the management of GDM among nurses’ capital of Bangladesh. Capacity building training should conduct regularly for young graduate nurses so that they can apply knowledge properly in the practice area.
背景:妊娠期糖尿病(GDM)占糖尿病合并妊娠的大多数病例。本研究旨在描述孟加拉国达卡护士关于GDM管理的知识和实践水平。方法:对达喀市3个保健中心的427名护士进行横断面调查。采用面对面访谈的半结构式问卷收集数据。所有数据均通过描述性和推断性统计技术进行分析。知识和实践得分按预设分数划分为差(Mean+1SD)。结果:本组被调查者的平均年龄为27.8±5.5岁,知识水平(包括基础知识和技术知识)均为中等水平,其中基础知识为66.3%,技术知识为67%。女护士对GDM的基础知识和实践较男护士好(p=0.002)。受访者的性别、受教育程度和工作场所与GDM管理的基本知识有显著的关联。受教育程度和婚姻状况与受访者的技术知识水平有显著的关联,而关于适当的GDM管理实践,只有受访者的家庭月收入显示出显著的关联。结论:结果显示孟加拉国护士都对GDM的管理存在认识和实践上的差距。应定期对年轻护士研究生进行能力建设培训,使他们能够在实践中正确应用知识。
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引用次数: 0
FLUSHING OF THE FOLLICLES IN OVUM PICK-UP PROCEDURES GIVES A BETTER CHANCE FOR PREGNANCY IN LOW OVARIAN RESERVE PATIENTS 在取卵过程中卵泡的冲洗为卵巢储备能力低的患者提供了更好的怀孕机会
Pub Date : 2022-01-01 DOI: 10.26502/ogr0101
S. Oral, A. Sismanoglu
Background: This study aims compare the pregnancy and live birth rates between the oocytes retrieved without follicular flushing FF(-) in the oocyte pick-up (OPU) procedure performed in women with diminished ovarian reserve (DOR) and those retrieved by follicular flushing FF(+). Results: The study was conducted among patients diagnosed with DOR according to Bologna criteria and applied to the clinic for IVF between 2017-2020. A total of 358 infertile women with follicles three and below on the hCG day, between the ages of 21 and 42, without severe male factor, without uterine anomaly, without uterine surgery, and who did not undergo PGD were included in the study. Each follicle was aspirated once in the OPU procedure, and if a follicle was retrieved, it was moved to the other follicle. If the follicle could not be retrieved, the oocyte was tried to be retrieved by flushing a maximum of 3 times. The number of oocytes retrieved, clinical pregnancy rate, and live birth rate were compared. Since all the oocytes retrieved in 143 patients were retrieved directly without the need for FF, it was named FF(-) group. Since at least one oocyte of the remaining 215 patients was retrieved by performing FF, it was named FF(+) group. Since some of the oocytes retrieved from 112 patients in the FF(+) group were retrieved with FF and some without FF, they were excluded from the study, and the remaining 103 cases formed the FF(+) group a total of 246 patients were compared. The mean number of MII oocytes ,the pregnancy rates , rates of live births and the abortion rates between two groups did not show any statistical difference. Conclusion: FF applied during oocyte retrieval in DOR did not positively affect the number of retrieved oocytes, clinical pregnancy, and live birth rates even doing this may decrease the pregnancy rate because of the probable low quality egg but we should not forget that if we did not do flushing after once we aspirated the follicle we would not be able to obtain any pregnancy at all in this patients.
背景:本研究的目的是比较卵巢储备功能减退(DOR)的妇女在卵母细胞提取(OPU)过程中未进行卵泡冲洗FF(-)的卵母细胞与卵泡冲洗FF(+)的卵母细胞的妊娠率和活产率。结果:该研究是在2017-2020年期间根据博洛尼亚标准诊断为DOR并应用于IVF临床的患者中进行的。共有358名在hCG日卵泡3及以下,年龄在21 - 42岁之间,无严重男性因素,无子宫异常,未做子宫手术,未做PGD的不孕女性被纳入研究。每个卵泡在OPU过程中被抽吸一次,如果一个卵泡被取出,它被移到另一个卵泡中。如果不能取出卵泡,则尝试通过冲洗最多3次来取出卵母细胞。比较取卵数、临床妊娠率和活产率。143例患者取卵均为直接取卵,无需FF,故命名为FF(-)组。由于其余215例患者中至少有1个卵母细胞通过FF回收,故命名为FF(+)组。由于从112例FF(+)组患者中取出的卵母细胞部分带有FF,部分没有FF,因此将其排除在研究之外,其余103例组成FF(+)组,共246例患者进行比较。两组平均MII卵母细胞数、妊娠率、活产率、流产率均无统计学差异。结论:在DOR的卵母细胞提取过程中应用FF对提取的卵母细胞数量、临床妊娠和活产率没有积极影响,即使这样做也可能会降低妊娠率,因为可能是低质量的卵子,但我们不应该忘记,如果我们在抽吸卵泡后不进行冲洗,我们将无法在该患者中获得任何妊娠。
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Obstetrics and gynecology research
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