Aim: The aim of the study was to determine the prevalence of abnormal uterine bleeding and its various patterns from the gynecologists across the country and the preferred therapy in the management of AUB. Material and Methods: The survey was conducted amongst 141 gynecologists across the country. Information was collected by filling up a questionnaire that contained information regarding menstrual cycle irregularities, preferred therapy and alternatives which can be preferred over hormonal prescriptions in case of therapy failure. Statistical data analysis was performed with Microsoft excel 2010 and expressed in percentages. Results: Prevalence of AUB as per this survey is in line with the global data which states that overall prevalence fluctuates in between 10-30%. In this survey, doctors reported 32.72% of females visit their clinic due to AUB. Females of reproductive age group accounted for a major percentage of menstrual irregularities and the most common condition quoted was menorrhagia in 16.06%. Doctors also shared their experience in terms of preferred therapy in the management of AUB and also the percentage of discontinuation/refusal by females for hormonal therapy. Conclusion: The result of the study concluded that significant number of female have issue of abnormal uterine bleeding and limitations of existing therapy leading to discontinuation/refusal opens the door for exploring still safer options in managing AUB.
{"title":"Abnormal Uterine Bleeding: A Doctor Centric Survey on Prevalence, Management and Limitations in Indian Context","authors":"Arif A Faruqui","doi":"10.26502/ogr022","DOIUrl":"https://doi.org/10.26502/ogr022","url":null,"abstract":"Aim: The aim of the study was to determine the prevalence of abnormal uterine bleeding and its various patterns from the gynecologists across the country and the preferred therapy in the management of AUB. Material and Methods: The survey was conducted amongst 141 gynecologists across the country. Information was collected by filling up a questionnaire that contained information regarding menstrual cycle irregularities, preferred therapy and alternatives which can be preferred over hormonal prescriptions in case of therapy failure. Statistical data analysis was performed with Microsoft excel 2010 and expressed in percentages. Results: Prevalence of AUB as per this survey is in line with the global data which states that overall prevalence fluctuates in between 10-30%. In this survey, doctors reported 32.72% of females visit their clinic due to AUB. Females of reproductive age group accounted for a major percentage of menstrual irregularities and the most common condition quoted was menorrhagia in 16.06%. Doctors also shared their experience in terms of preferred therapy in the management of AUB and also the percentage of discontinuation/refusal by females for hormonal therapy. Conclusion: The result of the study concluded that significant number of female have issue of abnormal uterine bleeding and limitations of existing therapy leading to discontinuation/refusal opens the door for exploring still safer options in managing AUB.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to assess the relation between different abnormalities of the yolk sac, serum level of Cancer Antigen 125 (CA-125) and serum level of Beta Human Chorionic Gonadotropin (β –HCG) as early predictors of first trimester pregnancy loss in patients with threatened miscarriage. Methods: This prospective observational study was conducted on 292 pregnant women between six to 13 weeks of gestation who were suffered threatened miscarriage. Visualization of yolk sac and diameter were recorded by transvaginal ultrasound . Maternal serum CA-125 and β HCG were also measured. Pregnancy outcome was the main outcome measure. Data was collected and tabulated. Results: There was highly Significant relation between YS size and pregnancy outcome (P<0.001). CA-125 and β-HCG were good predictors of miscarriage with accuracy 88%and 81.5% respectively. Conclusions: Yolk sac size and maternal serum CA-125 and β-HCG are good predictors of pregnancy outcome in first trimester threatened miscarriage.
{"title":"Ultrasonic and Laboratory Predictors of Pregnancy Loss in Patients with Threatened Miscarriage: A Three-Year Observational Study","authors":"A. Salah","doi":"10.26502/ogr025","DOIUrl":"https://doi.org/10.26502/ogr025","url":null,"abstract":"Objectives: The aim of this study was to assess the relation between different abnormalities of the yolk sac, serum level of Cancer Antigen 125 (CA-125) and serum level of Beta Human Chorionic Gonadotropin (β –HCG) as early predictors of first trimester pregnancy loss in patients with threatened miscarriage. Methods: This prospective observational study was conducted on 292 pregnant women between six to 13 weeks of gestation who were suffered threatened miscarriage. Visualization of yolk sac and diameter were recorded by transvaginal ultrasound . Maternal serum CA-125 and β HCG were also measured. Pregnancy outcome was the main outcome measure. Data was collected and tabulated. Results: There was highly Significant relation between YS size and pregnancy outcome (P<0.001). CA-125 and β-HCG were good predictors of miscarriage with accuracy 88%and 81.5% respectively. Conclusions: Yolk sac size and maternal serum CA-125 and β-HCG are good predictors of pregnancy outcome in first trimester threatened miscarriage.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To present case report a patient with clitoral cyst, following type II female genital cutting performed in childhood, management and literature review. Design: Report of cases managed and review of available current literatures. Setting: University College Hospital Ibadan. Patients: The case was a 30 year old Para 2+0 , 2 alive, known hypertensive, with perineal swelling since childhood. She presented 30 years later with increasing size of the clitoral swelling associated with pain. Management: Surgical excision of the cyst following thorough evaluation of the patients. Results: Better cosmetic outcome, vulvar discomfort subsided and improved sexual satisfaction post-operatively. Conclusion: While a good cosmetic and stoppage of vulvar discomfort can be managed with acceptable outcomes, these case, again, brings to attention of persistence of unacceptable female genital cutting with attendant effects even in the 21st century. Also, to let us know that there is need for more and continuous awareness creation of the need to stop this dehumanizing practice, of female genital cutting, which is of no health importance, rather numerous adverse sequelae.
{"title":"Acquired Clitoromegaly Cyst: Consequence of Persistent Unorthodox Practice in the 21st Century","authors":"O. Awolude, Oluyomi Akinyotu","doi":"10.26502/ogr020","DOIUrl":"https://doi.org/10.26502/ogr020","url":null,"abstract":"Objective: To present case report a patient with clitoral cyst, following type II female genital cutting performed in childhood, management and literature review. Design: Report of cases managed and review of available current literatures. Setting: University College Hospital Ibadan. Patients: The case was a 30 year old Para 2+0 , 2 alive, known hypertensive, with perineal swelling since childhood. She presented 30 years later with increasing size of the clitoral swelling associated with pain. Management: Surgical excision of the cyst following thorough evaluation of the patients. Results: Better cosmetic outcome, vulvar discomfort subsided and improved sexual satisfaction post-operatively. Conclusion: While a good cosmetic and stoppage of vulvar discomfort can be managed with acceptable outcomes, these case, again, brings to attention of persistence of unacceptable female genital cutting with attendant effects even in the 21st century. Also, to let us know that there is need for more and continuous awareness creation of the need to stop this dehumanizing practice, of female genital cutting, which is of no health importance, rather numerous adverse sequelae.","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ES-2 Ovarian Cancer Cells Present a Genomic Profile Inconsistent with their Reported History","authors":"Eric J Devor, Jace R Lapierre, David P Bender","doi":"10.26502/ogr072","DOIUrl":"https://doi.org/10.26502/ogr072","url":null,"abstract":"","PeriodicalId":74336,"journal":{"name":"Obstetrics and gynecology research","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69352319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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