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Workplace protection factors--supplied air hood. 工作场所保护因素——送风罩。
T. J. Nelson, T. H. Wheeler, T. Mustard
Several organizations list assigned protection factors. For supplied air hoods, the value of the assigned protection factors varies from <10 to 2,000 depending on the organization. Workplace protection factors (WPFs) of a supplied air hood were measured during aircraft sanding and painting operations on several types of aircraft to evaluate whether the American National Standard Z88.2 (1992) assigned protection factor of 1,000 was realistic. The primary contaminant during these activities is strontium chromate. Samples collected inside the hood show that employees during sanding and painting operations were not exposed to strontium. The respirator performed adequately. This study is consistent with other simulated and WPF studies in that the ANSI Z88.2 WPF of 1,000 is supported.
一些组织列出了指定的保护因素。对于送风罩,指定保护系数的值从<10到2,000不等,具体取决于组织。在几种类型的飞机上进行喷砂和喷漆作业时,测量了供气罩的工作场所保护系数(wpf),以评估美国国家标准Z88.2(1992)指定的1,000保护系数是否现实。这些活动中的主要污染物是铬酸锶。在引擎盖内收集的样本表明,在打磨和喷漆作业中的员工没有接触到锶。呼吸器表现良好。本研究与其他模拟和WPF研究一致,支持ANSI Z88.2 WPF的1000。
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引用次数: 10
Respiratory protection as a function of respirator fitting characteristics and fit-test accuracy. 呼吸防护功能取决于呼吸器的适配特性和适配测试的准确性。
D. Campbell, C. Coffey, S. Lenhart
The fitting characteristics of particulate respirators are no longer assessed in the National Institute for Occupational Safety and Health respirator certification program. It is important for respirator program administrators to understand the implications of that change and the additional burden it may impose. To address that issue, a typical respirator fit-testing program is analyzed using a mathematical model that describes the effectiveness of a fit-testing program as a function of the fitting characteristics of the respirator and the accuracy of the fittesting method. The model is used to estimate (1) the respirator assignment error, the percentage of respirator wearers mistakenly assigned an ill-fitting respirator; (2) the number of fit-test trials necessary to qualify a group of workers for respirator use; and (3) the number of workers who will fail the fit-test with any candidate respirator model and thereby fail to qualify for respirator use. Using data from previous studies, the model predicts respirator assignment errors ranging from 0 to 20%, depending on the fitting characteristics of the respirator models selected and the fit-testing method used. This analysis indicates that when respirators do not necessarily have good fitting characteristics, respirator program administrators should exercise increased care in the selection of respirator models and increased care in fit-testing. Also presented are ways to assess the fitting characteristics of candidate respirator models by monitoring the first-time fit-testing results. The model demonstrates that significant public health and economic benefits can result when only respirators having good fitting characteristics are purchased and respirators are assigned to workers using highly accurate fit-testing methods.
颗粒呼吸器的适配特性不再在国家职业安全与健康研究所呼吸器认证计划中进行评估。对于呼吸器项目管理员来说,了解这一变化的含义及其可能带来的额外负担是很重要的。为了解决这个问题,本文使用一个数学模型来分析一个典型的呼吸器适配测试程序,该模型将适配测试程序的有效性描述为呼吸器的适配特性和适配方法的准确性的函数。该模型用于估计(1)呼吸器分配误差,即呼吸器佩戴者错误分配不合适呼吸器的百分比;(2)使一组工人有资格使用呼吸器所需的体能测试次数;(3)无法通过任何候选呼吸器型号的适配性测试,从而无法获得呼吸器使用资格的工人人数。利用以往研究的数据,该模型根据所选择的呼吸器模型的拟合特性和使用的拟合检验方法,预测呼吸器分配误差在0到20%之间。这一分析表明,当呼吸器不一定具有良好的贴合特性时,呼吸器项目管理员应在呼吸器型号的选择和贴合测试中更加谨慎。还介绍了通过监测首次匹配测试结果来评估候选呼吸器模型的拟合特性的方法。该模型表明,只有购买具有良好适配特性的呼吸器,并使用高度精确的适配测试方法将呼吸器分配给工人,才能产生显著的公共卫生和经济效益。
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引用次数: 32
Ion mobility spectrometric monitoring of phosdrin from foliage in greenhouse. 温室叶片磷素离子迁移率光谱监测。
K. Tuovinen, H. Paakkanen, O. Hänninen, J. Ruuskanen
The monitoring of Phosdrin (mevinphos; insecticide) from foliage and foliage extracts was achieved by an aspiration-type ion mobility spectrometer. This technique is based on ion mobility, which is proportional to the molecular weight, shape, and charge. The operation principle of the ion mobility spectrometer is to measure mobility distribution changes of product and reactant ions. This technique can measure positive and negative ion clusters at the same time in six different measuring electrodes. Each measuring electrode detects a different portion of the ion mobility distribution formed within the cell's radioactive source. The pattern recognition used is based on differences in the gas profiles for different compounds. This study shows that an ion mobility spectrometer can be used to monitor Phosdrin from foliage without the need for any time-consuming extraction procedure. The responses for Phosdrin-containing and background (control) samples were easily separated from each other. The responses declined as a function of time in the positive and sum response channels. In addition, the sum of the absolute values of signals at six measuring channels (sum response) were linearly proportional to the concentration of Phosdrin. Just before application (i.e., in background), this value was 41 bits, whereas these values were 10-fold, 11-fold, 8-fold, 6-fold, 5-fold, and 3.5-fold at the time points 4, 8, 11, 24, 50, and 72 hours after the spraying of Phosdrin.
Phosdrin (mevinphos)的监测用吸吸式离子迁移谱仪测定了叶片和叶片提取物中杀虫剂的含量。这种技术基于离子迁移率,它与分子量、形状和电荷成正比。离子迁移率谱仪的工作原理是测量生成物和反应物离子迁移率分布的变化。该技术可以在六个不同的测量电极上同时测量正负离子簇。每个测量电极检测细胞辐射源内形成的离子迁移率分布的不同部分。所使用的模式识别是基于不同化合物的气体分布的差异。本研究表明,离子迁移谱仪可用于监测叶片中的Phosdrin,而不需要任何耗时的提取过程。含有phosdrin的样品和背景(对照)样品的响应很容易相互分离。在正响应和和响应通道中,响应随时间的变化而下降。此外,六个测量通道的信号绝对值之和(响应总和)与Phosdrin浓度成线性关系。在施用前(即在后台),该值为41位,而在喷洒Phosdrin后4、8、11、24、50和72小时,这些值分别为10倍、11倍、8倍、6倍、5倍和3.5倍。
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引用次数: 2
Subchronic inhalation exposures to aerosols of three petroleum lubricants. 亚慢性吸入暴露于三种石油润滑油的气溶胶。
W. Dalbey
Subchronic inhalation studies were performed with three petroleum lubricants: generic cutting oil (GCO), generic gear oil (GO), and generic commercial engine oil (CEO). Each formulation had a mineral oil base. Sprague-Dawley rats were exposed 6 hours/day, 5 days/week for 13 weeks to aerosol concentrations of 0 (untreated controls), 0 (sham-exposed controls), approximately 50, 150, or 400-520 mg/m3. At necropsy, 15 rats/sex/group were sampled for serum chemistry (18 parameters), hematology, and weights of 13 organs. Testis and epididymis of males in the control and high-dose group were used for number of spermatids and morphology of epididymal sperm. Histopathological slides were evaluated for 22 or more organs. Pulmonary function tests were done on 10 additional males/group. Pulmonary hydroxyproline was measured in these rats for GCO and GO. Residual oil in the lungs was determined for GCO. The primary organ affected by exposures to these three formulations was the lung; the main observed effects were accumulation of foamy macrophages in pulmonary alveoli and alveolar walls, very mild thickening of alveolar walls due to foamy macrophages and a mixed cell infiltrate, and subtle epithelial hyperplasia. The foamy macrophages tended to group together in aggregates, and the aggregates seemed responsible for plaques seen visibly on the surface of the lung. These histological changes were accompanied by concentration-related increases in lung weight and pulmonary hydroxyproline, whereas pulmonary function tests were generally unaffected. Effects distal to the lung were more limited. These results indicated low toxicity of these aerosols in this model.
亚慢性吸入研究用三种石油润滑油进行:通用切削油(GCO),通用齿轮油(GO)和通用商用机油(CEO)。每种配方都有矿物油基础。将Sprague-Dawley大鼠每天暴露6小时,每周暴露5天,连续13周暴露于浓度为0(未处理对照组)、0(假暴露对照组)、约50、150或400-520 mg/m3的气溶胶中。剖检时,取15只大鼠/性别/组进行血清化学(18个参数)、血液学和13个器官的重量测定。对对照组和高剂量组雄鼠睾丸和附睾的精子数量和附睾精子形态进行测定。组织病理切片对22个或更多器官进行了评估。另外10名男性/组进行了肺功能检查。测定肺羟脯氨酸中GCO和GO的含量。肺内残油测定GCO。受这三种配方影响的主要器官是肺;观察到的主要影响是泡沫性巨噬细胞在肺泡和肺泡壁中积聚,泡沫性巨噬细胞和混合细胞浸润导致肺泡壁非常轻微的增厚,以及轻微的上皮增生。泡沫状巨噬细胞倾向于聚集在一起,聚集物似乎是肺表面可见斑块的原因。这些组织学变化伴随着肺重量和肺羟脯氨酸浓度相关的增加,而肺功能测试通常不受影响。远端肺部的影响更为有限。这些结果表明这些气溶胶在该模型中毒性较低。
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引用次数: 14
Determination of capsaicin and dihydrocapsaicin in air in a pickle and pepper processing plant. 泡菜和辣椒加工厂空气中辣椒素和二氢辣椒素的测定。
S. P. Tucker
A sampling and analytical method has been developed for measurement of capsaicin and dihydrocapsaicin in air. This method is applicable to measurement of the capsaicinoids in air in pepper processing plants and involves air sampling with a 13-mm glass fiber filter, recovery of the sample with 2 mL of acetonitrile, filtration of the solution, and analysis by high performance liquid chromatography with fluorescence detection. Excitation and emission wavelengths of the detector were 281 and 312 nm, respectively. Average recoveries were 98 to 104% after fortification of glass fiber filters with 0.13- to 2.9-microg quantities of capsaicin. Average recoveries of dihydrocapsaicin were 93 to 99% after fortification of glass fiber filters with 0.11- to 3.0-microg quantities. Detection limits of capsaicin and dihydrocapsaicin were 0.015 and 0.02 microg per sample, respectively. This method was used successfully for determining air concentrations of capsaicin and dihydrocapsaicin in a health hazard evaluation at a large pickle and pepper processing plant. An interesting phenomenon was the fact that the ratio of capsaicin to dihydrocapsaicin in each of the largest air samples was in the range of 0.3:1 to 0.5:1. Generally, capsaicin is the capsaicinoid that occurs in Capsicum fruit in the greatest relative abundance.
建立了空气中辣椒素和二氢辣椒素的采样分析方法。本方法适用于辣椒加工厂空气中辣椒素的测定,采用13mm玻璃纤维过滤器进行空气采样,用2ml乙腈回收样品,过滤溶液,采用荧光检测的高效液相色谱法进行分析。探测器的激发波长为281 nm,发射波长为312 nm。用0.13 ~ 2.9 μ g辣椒素强化玻璃纤维过滤器后,平均回收率为98 ~ 104%。在0.11 ~ 3.0 μ g玻纤滤料强化后,二氢辣椒素的平均回收率为93 ~ 99%。辣椒素和二氢辣椒素的检出限分别为0.015和0.02 μ g /份。该方法已成功用于某大型泡菜和辣椒加工厂空气中辣椒素和二氢辣椒素浓度的健康危害评价。一个有趣的现象是,在每个最大的空气样本中,辣椒素和二氢辣椒素的比例在0.3:1到0.5:1之间。一般来说,辣椒素是辣椒果实中相对丰度最大的辣椒素类物质。
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引用次数: 8
Interchangeability of gas detection tubes and hand pumps. 气体检测管和手动泵的互换性。
W. Haag
Users of gas detection tubes occasionally seek the convenience of using a single hand pump with different brands of tubes, to avoid the need to carry more than one pump. Several professional organizations recommend against such interchange. However, these recommendations appear to be based on a single study of pump designs that mostly are no longer in use. The present study was undertaken to determine if current hand pumps are interchangeable. Both piston-type and bellows-type hand pumps were evaluated by comparing pump flow profiles and test gas measurements with a variety of tubes. The results demonstrate that three piston hand pumps in common use (Sensidyne/Gastec GV/100, RAE Systems LP-1200, and Matheson-Kitagawa 8104-400A) are fully interchangeable. Two bellows pumps (Draeger Accuro and MSA Kwik-Draw) also are interchangeable with each other. Mixing of bellows and piston systems is often possible, but there are enough exceptions to conclude that such practice should be discouraged because it can give inaccurate readings. It is recommended that technical standards be adopted, such as total volume and an initial pump vacuum or a pump flow curve, to assess hand pump interchangeability. When two manufacturers' pumps meet the same standard and routine leak tests are conducted, interchangeability is scientifically valid and poses no risk to the end user while offering greater convenience.
气体检测管的用户偶尔会寻求使用不同品牌管的单手泵的便利性,以避免需要携带多个泵。一些专业组织建议不要进行这种交流。然而,这些建议似乎是基于对大多数已不再使用的泵设计的单一研究。本研究旨在确定当前的手动泵是否可互换。通过比较各种管道的泵流曲线和测试气体测量,对活塞式和波纹管式手动泵进行了评估。结果表明,常用的三个活塞手泵(Sensidyne/Gastec GV/100, RAE系统LP-1200和Matheson-Kitagawa 8104-400A)是完全可互换的。两个波纹管泵(Draeger Accuro和MSA Kwik-Draw)也可以相互互换。波纹管和活塞系统混合使用通常是可能的,但是也有足够的例外情况可以得出结论,不鼓励这种做法,因为它可能给出不准确的读数。建议采用技术标准,如总体积和初始泵真空度或泵流量曲线,以评估手动泵的互换性。当两个制造商的泵满足相同的标准并进行常规泄漏测试时,互换性是科学有效的,对最终用户不构成风险,同时提供更大的方便。
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引用次数: 5
Hydrocarbon solvent exposure data: compilation and analysis of the literature. 烃溶剂暴露数据:文献汇编与分析。
D. J. Caldwell, T. Armstrong, N. Barone, J. Suder, M. Evans
An occupational exposure database for hydrocarbon solvent end-use applications was constructed from the published literature. The database provides exposure assessment information for such purposes as regulatory risk assessments, support of industry product stewardship initiatives, and identification of applications in which limited exposure data are available. It is quantitative, documented, and based on credible data. Approximately 350 articles containing quantitative hydrocarbon solvent exposure data were identified using a search of computer databases of published literature. Many articles did not report sufficient details of the exposure data for inclusion in the database (e.g., full-shift exposure or task-based exposure data). Others were excluded because only limited summary statistics were provided, which precluded statistical analysis of the data (e.g., arithmetic mean concentration presented, but no sample number). Following evaluation, 16,880 hydrocarbon solvent exposure measurements from 99 articles were entered into a database for analysis. Methods used to identify and evaluate published solvent exposure data are described along with more detailed analysis of worker exposure to hydrocarbon solvents in three major end-use applications: painting and coating, printing, and adhesives. Solvent exposures were evaluated against current ACGIH threshold limit values (TLVs) and trends were identified. Limited quantitative data are available prior to 1970. In general, reported hydrocarbon solvent exposures decreased fourfold from 1960 to 1998, were below the TLVs applicable to specific hydrocarbon solvents at the time, and on average have been below 40% of the TLV since 1980. The database already has proved valuable; however, the utility of published exposure data could be further improved if authors consistently reported essential data elements and supporting information.
根据已发表的文献,构建了烃类溶剂最终用途的职业暴露数据库。该数据库提供暴露评估信息,用于监管风险评估、支持行业产品管理倡议以及识别可获得有限暴露数据的应用。它是定量的,有文件记录的,基于可靠的数据。通过检索已发表文献的计算机数据库,确定了大约350篇含有定量烃溶剂暴露数据的文章。许多文章没有报告足够详细的暴露数据以纳入数据库(例如,全班暴露或基于任务的暴露数据)。其他人被排除,因为只提供了有限的汇总统计,这妨碍了对数据的统计分析(例如,提供了算术平均浓度,但没有样本数量)。经过评估,来自99篇文章的16,880个碳氢化合物溶剂暴露测量值被输入数据库进行分析。本文描述了用于识别和评估已发表的溶剂暴露数据的方法,并详细分析了工人在三种主要最终用途(油漆和涂料、印刷和粘合剂)中暴露于碳氢化合物溶剂的情况。根据目前的ACGIH阈值(TLVs)评估溶剂暴露,并确定趋势。1970年以前的数量数据有限。总的来说,报告的碳氢溶剂暴露量从1960年到1998年减少了4倍,低于当时适用于特定碳氢溶剂的TLV,自1980年以来平均低于TLV的40%。这个数据库已经被证明是有价值的;但是,如果作者始终如一地报告基本数据元素和支持信息,则可以进一步提高已发表的暴露数据的效用。
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引用次数: 55
Evaluation of portable air samplers for monitoring airborne culturable bacteria. 监测空气中可培养细菌的便携式空气采样器的评价。
S. Mehta, D. Bell-Robinson, T. O. Groves, L. Stetzenbach, D. Pierson
Airborne culturable bacteria were monitored at five locations (three in an office/laboratory building and two in a private residence) in a series of experiments designed to compare the efficiency of four air samplers: the Andersen two-stage, Burkard portable, RCS Plus, and SAS Super 90 samplers. A total of 280 samples was collected. The four samplers were operated simultaneously, each sampling 100 L of air with collection on trypticase soy agar. The data were corrected by applying positive hole conversion factors for the Burkard portable, Andersen two-stage, and SAS Super 90 air samplers, and were expressed as log10 values prior to statistical analysis by analysis of variance. The Burkard portable air sampler retrieved the highest number of airborne culturable bacteria at four of the five sampling sites, followed by the SAS Super 90 and the Andersen two-stage impactor. The number of bacteria retrieved by the RCS Plus was significantly less than those retrieved by the other samplers. Among the predominant bacterial genera retrieved by all samplers were Staphylococcus, Bacillus, Corynebacterium, Micrococcus, and Streptococcus.
在一系列实验中,在五个地点(三个在办公室/实验室大楼,两个在私人住宅)监测空气中可培养细菌,以比较四种空气采样器的效率:Andersen两级采样器、Burkard便携式采样器、RCS Plus和SAS Super 90采样器。共采集样本280份。4个采样器同时操作,每个采样100 L空气,收集胰酶大豆琼脂。通过对Burkard便携式、Andersen两级和SAS Super 90空气采样器应用正孔转换因子对数据进行校正,并在方差分析前表示为log10值。Burkard便携式空气采样器在五个采样点中的四个采集到的空气中可培养细菌数量最多,其次是SAS Super 90和Andersen两级冲击器。RCS Plus检出的细菌数量明显少于其他样品。所有采样器检索到的优势细菌属为葡萄球菌、芽孢杆菌、棒状杆菌、微球菌和链球菌。
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引用次数: 33
Building materials used in construction can affect indoor fungal levels greatly. 建筑中使用的建筑材料对室内真菌水平影响很大。
P. Ellringer, K. Boone, S. Hendrickson
This article summarizes the results of a fungal investigation of a new, seven-story, 170-room hotel. The owners of the building were refused an occupancy permit by local building officials because of concerns about fungal contamination. This article discusses the processes that were used to investigate and abate the fungal concerns in this building. This investigation involved comparing fungal infestation levels in various building materials, including two different types of gypsum wallboard. During initial testing the indoor air concentrations of problematic fungi were up to 50 times higher than outdoor levels. After the removal of the fungal-infested materials and the replacement with more acceptable materials, the indoor air concentration of problematic fungi dropped to less than one-fourth of outdoor levels.
本文总结了一个新的,七层,170间客房的酒店真菌调查的结果。由于担心真菌污染,当地建筑官员拒绝了该建筑业主的入住许可。本文讨论了用于调查和减轻该建筑真菌问题的过程。这项调查涉及比较各种建筑材料中的真菌感染水平,包括两种不同类型的石膏墙板。在最初的测试中,室内空气中问题真菌的浓度比室外高50倍。在去除真菌滋生的材料并替换为更可接受的材料后,室内空气中问题真菌的浓度降至室外水平的四分之一以下。
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引用次数: 33
Lead exposure among workers renovating a previously deleaded bridge: comparison of trades, work tasks. 修复先前被拆除桥梁的工人的铅暴露:行业、工作任务的比较。
J. Johnson, S. Reynolds, L. Fuortes, W. R. Clarke
Airborne and surface lead exposures were evaluated for construction trade groups at a previously deleaded bridge renovation site in the midwestern United States. Although all lead-based paint should have been removed, old layers of leaded paint were still present on some sections of the bridge. Ironworkers performing metal torch cutting had the highest exposures (188 microg/m3), followed by workers engaged in clean-up operations and paint removal (p < 0.001). Respirators were most frequently worn by workers with the greatest lead exposures; however, laborers performing clean-up operations had exposures to lead dust of 43 microg/m3 and often wore no respiratory protection. Wipe samples revealed that almost all contractor vehicles were contaminated with lead. Heavy equipment operators with low airborne lead exposure had the highest levels of surface contamination in personal vehicles (3,600 microg/m2). Laborers cleaning structural steel with compressed air and ironworkers exposed to lead fumes from cutting had the highest concentrations of lead dust on clothing (mean 4,766 microg/m2). Handwashing facilities were provided, but were infrequently used. No separate clothes changing facility was available at the site. The potential for "take-home" contamination was high, even though this site was thought to be relatively free of lead. Construction contractors and their workers need to be aware that previous deleading of a site may not preclude exposure to significant amounts of lead.
在美国中西部一个先前被取消的桥梁翻新现场,对建筑贸易团体进行了空气和地面铅暴露评估。虽然所有含铅油漆都应该被清除,但在桥的某些部分仍然存在旧的含铅油漆层。从事金属火炬切割的钢铁工人的接触量最高(188微克/立方米),其次是从事清洁作业和油漆去除的工人(p < 0.001)。接触铅最多的工人最常佩戴呼吸器;然而,从事清洁工作的工人暴露在43微克/立方米的铅尘中,而且经常没有佩戴呼吸防护装置。擦拭样本显示,几乎所有承包商的车辆都被铅污染了。空气中铅暴露量低的重型设备操作员的个人车辆表面污染水平最高(3,600微克/平方米)。用压缩空气清洁结构钢的工人和因切割而暴露在铅烟雾中的钢铁工人的衣服上的铅尘浓度最高(平均为4,766微克/平方米)。提供洗手设施,但不经常使用。现场没有单独的换衣设施。“带回家”污染的可能性很高,尽管该地点被认为相对不含铅。建筑承包商和他们的工人需要意识到,以前的场地搬迁可能无法避免接触大量的铅。
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引用次数: 8
期刊
AIHAJ : a journal for the science of occupational and environmental health and safety
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