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Epidemiology and Burden of Treatment-Resistant Depression in Colombia: Analysis of the TRAL Study 哥伦比亚难治性抑郁症的流行病学和负担:TRAL研究的分析
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.007
Rodrigo Cordoba-Rojas , Eugenio Ferro , Lina Maria Agudelo Baena , Gabriela Kanevsky , Patricia Cabrera

Objectives

To estimate the prevalence of treatment-resistant depression (TRD) in Colombia, and characterize hospitalized major depressive disorder (MDD) patients for disability, health-related quality of life (HRQoL) and work-impairment.

Materials and methods

Adult MDD patients (n = 162) from 4 centers in Colombia, with a clinical diagnosis of MDD based on DSM-5 and MINI, were consecutively included. Patients with psychosis, schizophrenia, bipolar disorder, schizoaffective disorder, dementia, with severe chemical dependence or currently participating in another clinical trial were excluded. Patient reported outcomes and clinical assessment scales were used as outcomes with WPAI:D (work impairment), EQ-5D (QoL) and Sheehan Disability Scale, as well as healthcare resource utilization.

Results

Prevalence of TRD in Colombia among patients treated at psychiatric reference sites was 32.1% [24.9%; 39.3%], higher in private institutions. Most patients were females and single. 55% reported having moderate to severe problems with usual activities at the beginning of the study. Mean percent of working time missed due to depression was around 53%, and work impairment was roughly 67%. A mean of 2.85 days in the last seven were marked by lost school/work, with higher losses in TRD patients compared to non-TRD. Overall results for HRQoL were lower in TRD patients, but disability and work impairment were higher in non-TRD.

Conclusions

There is a high prevalence of mental disorders in Colombia, including TRD, impacting significantly HRQoL. The burden associated with them may be reduced by a most comprehensive and customized usage of therapies, including the innovations, and implementation of national mental health programs.
目的评估哥伦比亚难治性抑郁症(TRD)的患病率,并对住院重度抑郁症(MDD)患者的残疾、健康相关生活质量(HRQoL)和工作障碍进行特征描述。材料与方法来自哥伦比亚4个中心的成年MDD患者(n = 162),均根据DSM-5和MINI进行临床诊断。排除患有精神病、精神分裂症、双相情感障碍、分裂情感障碍、痴呆、严重化学依赖或目前正在参加其他临床试验的患者。以患者报告的结局和临床评估量表作为结局,以WPAI:D(工作障碍)、EQ-5D(生活质量)和Sheehan残疾量表以及医疗资源利用为结局。结果哥伦比亚精神科参考点治疗的患者中TRD患病率为32.1% [24.9%;39.3%],私立学校更高。患者多为单身女性。55%的人报告在研究开始时在日常活动中有中度到严重的问题。因抑郁而错过工作时间的平均比例约为53%,工作障碍约为67%。在过去的7天中,平均有2.85天旷课/旷工,与非TRD患者相比,TRD患者的旷课率更高。TRD患者的HRQoL总体结果较低,但非TRD患者的残疾和工作障碍较高。结论哥伦比亚包括TRD在内的精神障碍患病率较高,对HRQoL有显著影响。通过最全面和定制的治疗方法,包括创新和实施国家心理健康计划,可以减轻与之相关的负担。
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引用次数: 0
Intoxication Associated with Ayahuasca Consumption, Characterization, and Comparative Analysis of the Beverage's Components: A Case Report 中毒与死藤水的消费,表征和比较分析饮料的成分:一个案例报告
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.009
Edgar A. Estrella-Parra , José G. Avila-Acevedo , Ana M. García-Bores , José C. Rivera-Cabrera , Edgar F. Alarcón-Villaseñor , Ivone Alejandre-García , Francisco J. Alarcón-Aguilar

Introduction

Ayahuasca is a psychotropic beverage from South America, derived from Banisteriopsis caapi and Psychotria viridis. The beverage contains alkaloids such as β-carbolines and dimethyltryptamine (DMT), which alter the psychoactive functions associated with perception and thought processes. Its consumption in the countries of origin, such as Brazil, Colombia, and Peru, is prevalent. Its use has been popularized worldwide, especially in the European Union and North America, where the ayahuasca samples are introduced from South America.

Objective

This article presents the case report of a Mexican ayahuasca user with clinical symptoms of poisoning.

Clinical case

A 24-year-old man, habitual consumer of ayahuasca, arrived at emergency room presenting cognitive decline and a fluctuating course of delirium, stupor, and disorientation. The patient's blood samples were compared using HPLC/ESI-MS/MS with the extract consumed, with other traditional Colombian ayahuasca samples, and with standard chemicals, aiming to determine whether the components of ayahuasca were present in the patient's blood. The same blood sample was subjected to a bioinformatics analysis (KNIME 4.4.2-version, based on OpenMS) to detect other drugs probably consumed by the patient.

Conclusions

The principal components of ayahuasca in the blood sample were identified: DMT, harmaline, harmine, harmol, bufotenine, and tetrahydro harmine. In addition, other narcotic drugs, such as 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol, amphetamine, and norcocaine, were also detected. The poisoning can be associated with ayahuasca consumption and its interaction with other drugs.
死藤水是一种来自南美洲的精神类饮料,由Banisteriopsis caapi和psychotriia viridis衍生而来。这种饮料含有生物碱,如β-碳碱和二甲基色胺(DMT),它们会改变与感知和思维过程相关的精神活动功能。它的消费在原产国,如巴西、哥伦比亚和秘鲁,是普遍的。死藤水的使用已经在世界范围内普及,特别是在欧盟和北美,死藤水的样品是从南美引进的。目的报道一例墨西哥死藤水服用者出现中毒临床症状的病例报告。临床病例:一名24岁男性,死藤水的习惯性消费者,因认知能力下降和谵妄、昏迷和定向障碍的波动过程而被送往急诊室。使用HPLC/ESI-MS/MS将患者血液样本与所消耗的提取物、其他传统哥伦比亚死藤水样本以及标准化学品进行比较,以确定患者血液中是否存在死藤水的成分。对同一血样进行生物信息学分析(KNIME 4.4.2版本,基于OpenMS),以检测患者可能使用的其他药物。结论从血样品中鉴定出死藤水的主要成分:DMT、毒蜂碱、毒蜂碱、毒蜂碱、丁福藤碱和四氢毒蜂碱。此外,还检测到其他麻醉药物,如11-no -9-羧基-Δ(9)-四氢大麻酚、安非他明和去甲可卡因。中毒可能与死藤水的摄入及其与其他药物的相互作用有关。
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引用次数: 0
Delirium: Cognitive, Functionality, and Quality of Life Outcomes in Critically Ill Patients 谵妄:危重病人的认知、功能和生活质量
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.001
Martha Liliana Sánchez-Lozano , Cristian Daniel Restrepo-Ramírez , Laura Sofía Serna-Echeverri , Juan Darío Franco-Ramírez , Julio César Gutiérrez-Segura , Andrés Mauricio García-Cuevas

Objective

There is scarce evidence of the impact of delirium on the post-ICU outcomes of critically ill patients. This study assessed the effect of delirium on cognitive function, functionality, and quality of life after three months from discharge in critically ill patients.

Methods

A nested case–control study was realized from April to September 2018. The prevalence of delirium and its association with mortality was assessed, and the alterations in cognition, functionality, and quality of life in survivors of critical illness three months after discharge from the ICU.

Results

81 patients were included and evaluated with the CAM-ICU; 43 were defined as cases. The prevalence of delirium was 26%, and the mortality of patients with and without delirium was 35.4% vs. 10%, respectively. In the follow-up, the delirium group showed lower scores in the MMSE (p < 0.01), with a specific decline in the subdomains of orientation, calculation, and language/praxis compared with the control group. The delirium group showed a decreased score in the SF-36, with a significant decline in social function, emotional role, and mental health (p < 0.05). There were no differences observed in functionality measured by the PGC-IADL.

Conclusions

Education strategies are required to increase delirium awareness in ICU teams. Support from a mental health interdisciplinary team is needed to guide the preventive and rehabilitation interventions for post-ICU patients.
目的谵妄对危重患者icu后预后的影响尚缺乏证据。本研究评估危重病人出院后三个月谵妄对认知功能、功能和生活质量的影响。方法于2018年4 - 9月进行巢式病例对照研究。评估谵妄的患病率及其与死亡率的关系,以及重症患者出院后3个月认知、功能和生活质量的改变。结果共纳入81例患者,采用CAM-ICU进行评估;43例被定义为病例。谵妄的患病率为26%,有谵妄和无谵妄的死亡率分别为35.4%和10%。在随访中,谵妄组的MMSE得分较低(p < 0.01),与对照组相比,定向、计算和语言/实践的子域明显下降。谵妄组SF-36得分下降,社会功能、情感角色、心理健康显著下降(p < 0.05)。PGC-IADL测量的功能没有观察到差异。结论提高ICU团队谵妄意识需要采取教育策略。需要心理健康跨学科团队的支持来指导icu后患者的预防和康复干预。
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引用次数: 0
Emotion Regulation Mediates the Association Between Child Abuse and Adult Suicidal Ideation: An Exploratory Study 情绪调节在儿童虐待与成人自杀意念之间的中介作用:一个探索性研究
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.003
Pablo D. Valencia, Anabel De la Rosa-Gómez
Emotion regulation (ER) problems have been shown to mediate the relationship between childhood maltreatment and suicidality. However, evidence is sparse regarding specific types of maltreatment and ER strategies involved.

Objective

To explore cognitive reappraisal and expressive suppression as potential mediators of the association between three types of child abuse (sexual, physical, and emotional) and suicidal ideation.

Methods

A cross-sectional design was used. A total of 375 Mexican young adults (77.1% female) responded to an online survey. Measures of child abuse, ER, and suicidal ideation were administered. Three mediation models were tested (one for each type of abuse), each with two mediators (the two ER strategies). The presence of mediation was formally tested through bootstrapping applied to the indirect effects.

Results

Expressive suppression significantly mediated the relationship between two types of abuse (physical and emotional) and suicidal ideation. Also, lower use of cognitive reappraisal mediated the association between sexual abuse and suicidal ideation.

Conclusions

Studying different types of abuse and ER strategies separately provides a more complete understanding of how suicidal thoughts develop. This could also affect how interventions are tailored for different groups. The present results can be used as a starting point for further, more detailed research.
情绪调节(ER)问题已被证明是儿童虐待与自杀之间的中介关系。然而,关于具体类型的虐待和所涉及的急诊室策略的证据很少。目的探讨认知重评价和表达抑制在三种类型的儿童虐待(性、身体和情感)与自杀意念之间的潜在中介作用。方法采用横断面设计。共有375名墨西哥年轻人(77.1%为女性)参与了一项在线调查。对儿童虐待、急诊室和自杀意念进行测量。测试了三个中介模型(每种类型的滥用一个),每个模型都有两个中介(两种ER策略)。通过应用于间接效应的自举,正式测试了中介的存在。结果压抑在躯体虐待和精神虐待两种虐待类型与自杀意念之间具有显著中介作用。此外,较低的认知重评使用介导了性虐待和自杀意念之间的关联。结论:分别研究不同类型的虐待和急诊室策略可以更全面地了解自杀念头是如何产生的。这也可能影响针对不同群体的干预措施。目前的结果可以作为一个起点,为进一步,更详细的研究。
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引用次数: 0
Consumption of Alcohol Upon Admission to the Emergency Department in Patients With Trauma 急诊创伤患者入院时的酒精消耗量
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.006
Nelcy Rodriguez-Malagón , Atilio Moreno-Carrillo , Miguel L. León-Méndez , Daniel García Vargas , María Fernanda Otálora Ribero , Felipe Botero-Rodríguez , Laura C. Herrera-Daza , Gustavo A. Flórez-Gonzalez , Carlos Gómez-Restrepo

Aim

For 2016, around 32.5% of the population consumed alcoholic beverages. This is related to 1.6% of the disability-adjusted life years. Also, an association is described between trauma severity and a positive alcohol test on admission to the emergency room. In Colombia, the prevalence of alcohol consumption during the last year is 17.8–42.5%. However, the prevalence of alcohol consumption upon admission to emergency services is unknown. We aim to estimate the prevalence of alcohol consumption in cases admitted to an emergency room.

Methods

This was a cross-sectional study. Data were collected during four months in an emergency room located in a fourth-level hospital. Researchers interviewed participants to complete a questionnaire, additionally, a qualitative alcohol test was carried out with an alcohol-sensor FST, and the AUDIT-C scale was used to screen for alcohol abuse.

Results

In 2524 patients, there was a prevalence of alcohol consumption on admission to the emergency room of 2.34%, and a median result of the quantitative test of 1.22 mg/ml. We found that as ethanol levels increased, there was a greater potential for discrimination among the patients who identified themselves with potential risky consumption based on the scale score.

Conclusions

Alcohol consumption is associated with high morbidity in patients admitted to the emergency room. This can increase the burden of disease and affect the quality of life. It is pertinent to recognize alcohol consumption as a possible focus to mitigate the impact of this condition on the well-being of patients and resources allocation.
2016年,约32.5%的人口饮用酒精饮料。这与1.6%的残疾调整生命年有关。此外,创伤严重程度与进入急诊室时酒精测试呈阳性之间存在关联。在哥伦比亚,去年酒精消费的流行率为17.8% - 42.5%。然而,入院时酒精消费的普遍程度尚不清楚。我们的目的是估计在急诊室入院的病例中酒精消费的流行程度。方法采用横断面研究。数据是在一家四级医院的急诊室收集的,为期四个月。研究人员对参与者进行了问卷调查,并使用酒精传感器FST进行了定性酒精测试,并使用AUDIT-C量表筛查酒精滥用情况。结果2524例患者入院时饮酒率为2.34%,定量检验中位数为1.22 mg/ml。我们发现,随着乙醇含量的增加,根据量表得分确定自己有潜在风险消费的患者之间存在更大的歧视可能性。结论酒精摄入与急诊患者的高发病率有关。这可能增加疾病负担并影响生活质量。认识到酒精消费可能是减轻这种情况对患者福祉和资源分配影响的一个重点,这是相关的。
{"title":"Consumption of Alcohol Upon Admission to the Emergency Department in Patients With Trauma","authors":"Nelcy Rodriguez-Malagón ,&nbsp;Atilio Moreno-Carrillo ,&nbsp;Miguel L. León-Méndez ,&nbsp;Daniel García Vargas ,&nbsp;María Fernanda Otálora Ribero ,&nbsp;Felipe Botero-Rodríguez ,&nbsp;Laura C. Herrera-Daza ,&nbsp;Gustavo A. Flórez-Gonzalez ,&nbsp;Carlos Gómez-Restrepo","doi":"10.1016/j.rcpeng.2025.10.006","DOIUrl":"10.1016/j.rcpeng.2025.10.006","url":null,"abstract":"<div><h3>Aim</h3><div>For 2016, around 32.5% of the population consumed alcoholic beverages. This is related to 1.6% of the disability-adjusted life years. Also, an association is described between trauma severity and a positive alcohol test on admission to the emergency room. In Colombia, the prevalence of alcohol consumption during the last year is 17.8–42.5%. However, the prevalence of alcohol consumption upon admission to emergency services is unknown. We aim to estimate the prevalence of alcohol consumption in cases admitted to an emergency room.</div></div><div><h3>Methods</h3><div>This was a cross-sectional study. Data were collected during four months in an emergency room located in a fourth-level hospital. Researchers interviewed participants to complete a questionnaire, additionally, a qualitative alcohol test was carried out with an alcohol-sensor FST, and the AUDIT-C scale was used to screen for alcohol abuse.</div></div><div><h3>Results</h3><div>In 2524 patients, there was a prevalence of alcohol consumption on admission to the emergency room of 2.34%, and a median result of the quantitative test of 1.22<!--> <!-->mg/ml. We found that as ethanol levels increased, there was a greater potential for discrimination among the patients who identified themselves with potential risky consumption based on the scale score.</div></div><div><h3>Conclusions</h3><div>Alcohol consumption is associated with high morbidity in patients admitted to the emergency room. This can increase the burden of disease and affect the quality of life. It is pertinent to recognize alcohol consumption as a possible focus to mitigate the impact of this condition on the well-being of patients and resources allocation.</div></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"54 2","pages":"Pages 243-249"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construct Validity of the COVID-19 Peritraumatic Distress Index (CPDI) in a Peruvian Sample During COVID-19 Lockdown and its Relationship With Anxiety and Depression Using Structural Equation Modeling 用结构方程模型分析秘鲁样本在COVID-19封锁期间的COVID-19创伤周围痛苦指数(CPDI)的结构效度及其与焦虑和抑郁的关系
Pub Date : 2025-04-01 DOI: 10.1016/j.rcpeng.2025.10.002
Bruno Pedraz-Petrozzi , Fabian Böttcher , Martín Arevalo-Flores , Víctor Anculle-Arauco , Hever Krüger-Malpartida

Background

The main aims of this study were to adapt the COVID-19 peritraumatic distress index (CPDI) to the Peruvian population and to establish a model explaining depression using CPDI values and anxiety symptoms during the COVID-19 lockdown. Finally, we sought predictive values of the obtained CPDI factors for depression and anxiety as a secondary aim.

Materials and methods

An exploratory factor analysis (n = 300) was performed, followed by confirmatory factor analysis in a second phase (n = 1135). To explain depression scores during the COVID-19 lockdown, we performed structural equation modeling (SEM). Finally, we performed a hierarchical regression model (HRM) to evaluate the amount of explained variance of the CPDI factors above depression, anxiety, and socio-demographic variables.

Results

A 2-factor solution (rumination and stress) for the CPDI (p < 0.001; CFI = 0.99) was found. Concerning the SEM, our model was able to explain 81% of the depression scores (p < 0.001; CFI = 0.98). Finally, in the HRM, rumination could explain 17% additional variance in depression (p < 0.001) and 28% in anxiety (p < 0.001). However, stress showed collinearity with depression and anxiety, not continuing for further HRM analysis.

Conclusions

Our results showed a 2-factor solution for the CPDI. Moreover, our SEM model showed that female sex, younger age, and incomplete education (with high COVID-related stress and anxiety) lead to more depression symptoms during the COVID-19 lockdown. Finally, our HRM showed that people who frequently ruminate during the COVID-19 lockdown are more afraid and negatively affected.
本研究的主要目的是使COVID-19创伤后痛苦指数(CPDI)适用于秘鲁人口,并建立一个模型,利用CPDI值和COVID-19封锁期间的焦虑症状来解释抑郁症。最后,我们寻求获得的CPDI因素对抑郁和焦虑的预测价值作为次要目的。材料与方法进行探索性因素分析(n = 300),第二阶段进行验证性因素分析(n = 1135)。为了解释COVID-19封锁期间的抑郁评分,我们进行了结构方程模型(SEM)。最后,我们使用层次回归模型(HRM)来评估CPDI因素在抑郁、焦虑和社会人口变量之上的解释方差量。结果发现反刍和应激两因素对CPDI的影响(p < 0.001; CFI = 0.99)。关于扫描电镜,我们的模型能够解释81%的抑郁得分(p < 0.001; CFI = 0.98)。最后,在人力资源管理中,反刍可以解释17%的抑郁额外方差(p < 0.001)和28%的焦虑(p < 0.001)。然而,压力与抑郁和焦虑呈共线性,进一步的人力资源管理分析没有继续。结论sour结果显示CPDI为双因子解。此外,我们的扫描电镜模型显示,在COVID-19封锁期间,女性、年龄较小和教育不完整(与COVID-19相关的高度压力和焦虑)导致更多的抑郁症状。最后,我们的人力资源管理显示,在COVID-19封锁期间经常沉思的人更害怕,更容易受到负面影响。
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引用次数: 0
Clinical and Sociodemographic Variables as Risk Factors for Suicidal Behavior in Borderline Personality Disorder: A Restrospective Study 临床和社会人口学变量作为边缘型人格障碍患者自杀行为的危险因素:一项回顾性研究
Pub Date : 2025-01-01 DOI: 10.1016/j.rcpeng.2022.11.002
Íñigo Alberdi-Páramo , Germán Montero-Hernández , María Dolores Sáiz-González , Marina Díaz-Marsá , José Luis Carrasco-Perera

Introduction and objective

Suicidal behavior (SB) is nuclear in Borderline Personality Disorder (BPD). It is considered a symptom clinically relevant and with an important prognostic value. The literature describes different variables related to SB in BPD such as impulsivity, aggressiveness or hopelessness. There are not hardly any studies focused on the role of sociodemographic variables and their specific relationship with SB in BPD. The objective of this work is to identify which clinical and sociodemographic parameters could act as markers of suicide risk in BPD.

Methods

A cross-sectional, observational, and retrospective study was conducted of a sample of 134 patients diagnosed with BPD. The analysis of the association between variables was carried out with a multivariate negative binomial logistic regression model.

Results

SB is related to the number of siblings with statistical significance. Likewise, a greater number of suicide attempts is significantly associated with female gender, parenthood, permanent work, sick leaves and the number of previous hospital admissions. Both the presence of SB and a greater number of suicide attempts are significantly related to history of trauma in childhood and to the score in Hamilton Anxiety Rating Scale.

Conclusions

These parameters could act as risk factors for SB in BPD. The role of these variables could be the subject of further research projects in order to identify them in clinical practice.
前言与目的自杀行为是边缘型人格障碍(BPD)的核心。它被认为是一种临床相关的症状,具有重要的预后价值。文献描述了与BPD中SB相关的不同变量,如冲动性、攻击性或绝望。很少有研究关注社会人口学变量在BPD中的作用及其与SB的具体关系。这项工作的目的是确定哪些临床和社会人口学参数可以作为BPD自杀风险的标志。方法对134例诊断为BPD的患者进行横断面、观察性和回顾性研究。变量间的相关性分析采用多元负二项logistic回归模型。结果ssb与兄弟姐妹数相关,差异有统计学意义。同样,更多的自杀企图与女性性别、为人父母、长期工作、病假和以前的住院次数有很大关系。童年创伤史和汉密尔顿焦虑量表得分与SB的存在和较高的自杀企图数均有显著相关。结论这些指标可能是BPD患者发生SB的危险因素。这些变量的作用可能是进一步研究项目的主题,以便在临床实践中确定它们。
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引用次数: 0
Clinical and Functional Outcomes in Day Hospitals in Times of COVID-19 2019冠状病毒病期间日间医院的临床和功能结果
Pub Date : 2025-01-01 DOI: 10.1016/j.rcpeng.2022.12.001
Núria Estrada-Zambrano, Catarina Martinez-Ferreira, Julio Reyes-Figueroa

Objective

Mental health services have been clearly affected by the pandemic and its restrictions. In our day hospital units users attended on fewer days, group therapy was drastically reduced, the number of users in groups was limited and individual and group teletherapy was initiated. This study evaluates the impact of these changes on clinical and functional outcomes.

Methods

This is a descriptive study prospectively comparing two cohorts of users: those admitted and discharged from our day hospitals before or during the pandemic. All users received a multidisciplinary assessment at admission and discharge including clinician and user-rated scales on psychopathology, daily living skills, quality of life and caregiver burdens. Improvement in both groups was compared.

Results

Both cohorts were homogenous at admission. Length of admission was not different for the two groups, but users admitted during the pandemic attended the day hospital on significantly fewer days. Improvement observed in most scales was equivalent in both groups, suggesting a similar evolution of both cohorts.

Conclusions

Despite the reduction in assistance days and group therapeutic interventions no major changes were found in the outcomes of both groups. This study shows that careful adaptations and availability, even in critical situations, can result in equally effective treatments. Further research is essential to determine which of these adaptations should be maintained beyond the pandemic.
客观:卫生服务显然受到大流行病及其限制的影响。在我们的日间医院单位,用户就诊的天数减少,团体治疗大幅减少,小组用户数量有限,开始进行个人和团体远程治疗。本研究评估了这些变化对临床和功能结果的影响。方法这是一项描述性研究,前瞻性地比较了两组使用者:在大流行之前或期间在我们日间医院住院和出院的患者。所有使用者在入院和出院时都接受了多学科评估,包括临床医生和使用者评定的精神病理学、日常生活技能、生活质量和照护者负担量表。比较两组患者的改善情况。结果两组患者入院时均为同质性。两组的入院时间没有差异,但在大流行期间入院的用户在日间医院就诊的天数明显减少。在大多数量表中观察到的改善在两组中是相同的,这表明两个队列的进化相似。结论尽管减少了辅助治疗天数和团体治疗干预,但两组患者的预后无明显变化。这项研究表明,即使在危急情况下,谨慎的适应和可用性也能产生同样有效的治疗。为了确定在大流行之后应保持哪些适应措施,进一步的研究至关重要。
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引用次数: 0
Prevalence and Clinical and Polygraphic Characteristics of Patients With Postural Sleep Apnea Attended by a Colombian Health Institute in Bogotá, Colombia 在哥伦比亚波哥大<e:1>的哥伦比亚卫生研究所,体位性睡眠呼吸暂停患者的患病率、临床和多谱特征
Pub Date : 2025-01-01 DOI: 10.1016/j.rcpeng.2025.07.001
Juan Darío Jiménez-Meléndez , Juan Manuel Hernández-Miranda , Camilo Andrés Escobar-Sarmiento , Luis Felipe Romero-Moreno , Franklin Escobar-Córdoba

Objective

To determine the prevalence and polygraphic and clinical characteristics of patients with postural sleep apnea attended on a Colombian health institute at Bogotá, Colombia.

Methods

Prospective descriptive observational study of patients older than 18 years old who underwent a polygraphic study because of a suspected OSA during a 6-month period between 2022 and 2023.

Results

A total of 233 polygraphic recordings were done in different patients who met criteria for the study. Ninety-seven patients (43%) met criteria for positional apnea and 126 (57%) for non-positional apnea. Patients with postural apnea had lower AHI (p < 0.001), lower body mass index (p = 0.002) and less hypertension (p = 0.002). NADIR was lower in patients with non-positional apnea, 75% vs 72% (p = 0.039). No significant statistical differences were found when comparing groups by age, sex or by Epworth, STOP-BANG, FOSQ-10, or Friedman's tongue position scales.

Conclusions

Postural apnea is a prevalent condition in Colombian population. According to our results these patients tend to have a lower severity of sleep apnea measured by AHI, lower BMI and less high blood pressure.
目的了解在哥伦比亚波哥大的哥伦比亚卫生机构就诊的体位性睡眠呼吸暂停患者的患病率、多谱图和临床特征。方法前瞻性描述性观察研究,研究对象是在2022年至2023年6个月期间因疑似OSA而接受测谎研究的18岁以上患者。结果在符合研究标准的不同患者中共进行了233次测谎记录。97例(43%)符合体位性呼吸暂停标准,126例(57%)符合非体位性呼吸暂停标准。体位性呼吸暂停患者的AHI较低(p <;0.001),较低的身体质量指数(p = 0.002)和较少的高血压(p = 0.002)。非体位呼吸暂停患者的NADIR较低,分别为75%和72% (p = 0.039)。当按年龄、性别或Epworth、STOP-BANG、FOSQ-10或Friedman舌位量表进行分组比较时,没有发现显著的统计学差异。结论体位性呼吸暂停是哥伦比亚人群的常见病。根据我们的结果,这些患者往往有较低的AHI测量睡眠呼吸暂停的严重程度,较低的BMI和较少的高血压。
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引用次数: 0
Characteristics of Stressful Life Events and Its Relationship With Body Disperception in Patients With Eating Disorders 饮食失调患者应激性生活事件特征及其与身体知觉的关系
Pub Date : 2025-01-01 DOI: 10.1016/j.rcpeng.2023.04.002
Ester Idini , Pamela Paredes-Carreño , David Valera-Ceamanos

Objective

A distorted body image and body dissatisfaction (BD) are key features of eating disorders (ED). Stressful life events (SLEs) are involved in the evolution of the illness. The study aims to evaluate the relationship between SLEs and disturbance in body image.

Method

Cross-sectional, retrospective study. ED participants were outpatients from the unit care of ED. Healthy subjects (HS) were recruited by general advisements. A final sample of 119 (78 patients and 41 HS) was recruited. The traumatic life event questionnaire, the dissociative experiences scale, the Contour Drawing Rating Scale, and the eating disorder inventory (EDI) were used for assessment.

Results

No differences between groups were found in mean age, sex, level of study, or SLEs prevalence. ED patients reported significantly more levels of dissociative experiences, BD, and body misperception. ED patients who reported SLEs presented more levels of dissociation, bulimia, perfectionism, impulsivity, and overestimation of the shape in the mirror. Besides, patients who overestimated their shape seemed to show more impulsivity. BD correlated with social insecurity and binging in the control group. HS with overestimation of their shape presented more punctuation in the EDI subscale of bulimia.

Conclusions

ED patients tend to overestimate their bodies more than HS both when they look in the mirror and when they feel their shape. Those with a greater number of SLEs have greater levels of dissociation. The presence of interpersonal SLEs determined more perfectionism, impulsivity, a distorted body image in the mirror, and a drive of thinness only in ED patients, while healthy subjects reported more anxiety, social insecurity, and non-planned impulsivity.
目的身体形象扭曲和身体不满意(BD)是进食障碍(ED)的主要特征。应激性生活事件(SLEs)与疾病的演变有关。本研究旨在评估SLEs与身体形象障碍之间的关系。方法横断面、回顾性研究。ED参与者是ED单元护理的门诊患者。健康受试者(HS)是根据一般建议招募的。最终的样本为119人(78名患者和41名HS)。采用创伤生活事件问卷、分离体验量表、等高线绘画评定量表和饮食失调量表(EDI)进行评估。结果各组之间在平均年龄、性别、学习水平或SLEs患病率方面没有差异。ED患者报告的解离体验、双相障碍和身体错觉水平明显更高。报告SLEs的ED患者表现出更多程度的分离、贪食、完美主义、冲动和对镜子形状的高估。此外,高估自己体型的患者似乎更容易冲动。对照组双相障碍与社会不安全感和暴饮暴食相关。形状高估的HS在贪食症EDI分量表中出现更多的标点符号。结论HS患者在照镜子和感觉形体时,对自身形体的高估程度高于HS患者。那些有更多SLEs的人有更大程度的分离。人际sel的存在决定了ED患者更多的完美主义、冲动、镜子里扭曲的身体形象和瘦身的动力,而健康受试者报告更多的焦虑、社会不安全感和非计划性冲动。
{"title":"Characteristics of Stressful Life Events and Its Relationship With Body Disperception in Patients With Eating Disorders","authors":"Ester Idini ,&nbsp;Pamela Paredes-Carreño ,&nbsp;David Valera-Ceamanos","doi":"10.1016/j.rcpeng.2023.04.002","DOIUrl":"10.1016/j.rcpeng.2023.04.002","url":null,"abstract":"<div><h3>Objective</h3><div>A distorted body image and body dissatisfaction (BD) are key features of eating disorders (ED). Stressful life events (SLEs) are involved in the evolution of the illness. The study aims to evaluate the relationship between SLEs and disturbance in body image.</div></div><div><h3>Method</h3><div>Cross-sectional, retrospective study. ED participants were outpatients from the unit care of ED. Healthy subjects (HS) were recruited by general advisements. A final sample of 119 (78 patients and 41 HS) was recruited. The traumatic life event questionnaire, the dissociative experiences scale, the Contour Drawing Rating Scale, and the eating disorder inventory (EDI) were used for assessment.</div></div><div><h3>Results</h3><div>No differences between groups were found in mean age, sex, level of study, or SLEs prevalence. ED patients reported significantly more levels of dissociative experiences, BD, and body misperception. ED patients who reported SLEs presented more levels of dissociation, bulimia, perfectionism, impulsivity, and overestimation of the shape in the mirror. Besides, patients who overestimated their shape seemed to show more impulsivity. BD correlated with social insecurity and binging in the control group. HS with overestimation of their shape presented more punctuation in the EDI subscale of bulimia.</div></div><div><h3>Conclusions</h3><div>ED patients tend to overestimate their bodies more than HS both when they look in the mirror and when they feel their shape. Those with a greater number of SLEs have greater levels of dissociation. The presence of interpersonal SLEs determined more perfectionism, impulsivity, a distorted body image in the mirror, and a drive of thinness only in ED patients, while healthy subjects reported more anxiety, social insecurity, and non-planned impulsivity.</div></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"54 1","pages":"Pages 112-123"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Revista Colombiana de psiquiatria (English ed.)
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