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Is it possible to prevent the progression of mild cognitive impairment through non-pharmacological treatments? 是否有可能通过非药物治疗来预防轻度认知障碍的进展?
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2023.11.001
Yeimi Yulie Romero Reyes, Lina Paola Andrade Valbuena

Introduction

Mild cognitive impairment produces slight cognitive and motor disturbances without affecting daily life during aging, however, if this symptomatology is not controlled, the speed of deterioration can increase, and even some cases of dementia can appear in the elderly population.

Objective

To describe non-pharmacological therapies that seek to prevent, control and reduce the symptoms of mild cognitive impairment.

Methods

An initial search was carried out in the databases of PubMed, Lilacs, EBSCO, ScienceDirect, Taylor & Francis and ProQuest. The results found were filtered through the PRISMA system and biases evaluated using the Cochrane Handbook for Systematic Reviews of Interventions.

Results

Four categories of non-pharmacological therapies were created, using 50 articles found in the search, which contribute to controlling and improving cognitive and motor areas, in order to reduce the symptoms presented by mild cognitive impairment. The treatments have different methods, instruments and objectives, so that no meta-analysis of the studies could be performed. In addition, limitations related to the sample, the effectiveness of the results and the methodological quality were found.

Conclusions

It was found that non-pharmacological therapies prevent, improve and control the symptoms caused by mild cognitive impairment, however, it is necessary to carry out more studies with better methodologies to corroborate these results.

简介:轻度认知障碍在衰老过程中产生轻微的认知和运动障碍,不影响日常生活,但如果这种症状不加以控制,恶化的速度会加快,甚至在老年人群中出现痴呆的情况。目的:描述旨在预防、控制和减轻轻度认知障碍症状的非药物治疗方法。方法:初步检索PubMed、Lilacs、EBSCO、ScienceDirect、Taylor & Francis、ProQuest等数据库。发现的结果通过PRISMA系统过滤,并使用Cochrane干预措施系统评价手册评估偏差。结果:利用在检索中发现的50篇文章,创建了四类非药物治疗方法,这些方法有助于控制和改善认知和运动区域,以减轻轻度认知障碍所呈现的症状。这些治疗有不同的方法、工具和目的,因此无法对这些研究进行meta分析。此外,还发现了与样本、结果的有效性和方法学质量有关的局限性。结论:非药物治疗可以预防、改善和控制轻度认知障碍患者的症状,但需要开展更多的研究,以更好的方法来证实这些结果。
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引用次数: 0
Burnout syndrome and depression in students of a Colombian medical school, 2018 哥伦比亚一所医学院学生的倦怠综合征和抑郁症,2018。
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.09.001
Felipe T. Serrano , Laura Tatiana Calderón Nossa , Carlos Andrés Gualdrón Frías , Jesús D. Mogollón G. , Christian R. Mejía

Introduction and objectives

Burnout syndrome (BS) has been evaluated in few populations of medical students, and its relationship with depression is even less studied. The objective was to determine the frequency of BS in medical students of the Universidad Pedagógica y Tecnológica de Colombia (UPTC), in Tunja, Colombia, as well as its association with depression and other social, economic, demographic, and academic factors.

Methods

An observational, analytical, cross-sectional study was carried out on 182 UPTC medical students during 2018. The Maslach Burnout Inventory-Student Survey (MBI-SS) was applied, with which 3 components were obtained to determine positive SB. This was crossed in the Stata 15 program for depression and other social, economic, demographic, and academic covariates with the Generalised Linear Model (GLM).

Results

Of 182 respondents, 51.4% were women. The median age was 21 years (20−23 years). 14% had BS, of which 48% had depression. In the multiple regression, BS was significantly associated with a higher frequency of depression (RPa = 5.54; IC95%, 2.36−13.02; P < 0.001) and the feeling of insufficient money (RPa = 4.37; IC95%, 1.95−9.83; P < 0.001), in contrast to a negative association with smoking (RPa = 0.13; IC95%, 0.06−0.30; P < 0.001) and being a woman (RPa = 0.32; IC95%, 0.12−0.82; P = 0.018). The age of onset of marijuana use was not significant.

Conclusions

BS shows a high association with increased depression and a feeling that the money is not enough at the end of the month, but it showed a negative association with tobacco consumption and being a woman. Such students should be detected to provide them with adequate academic support

简介和目的:对医学生中少数人群的倦怠综合征(BS)进行了评估,其与抑郁症的关系研究更少。目的是确定哥伦比亚Tunja的Pedagógica y Tecnológica哥伦比亚大学(UPTC)医科学生中BS的频率,以及其与抑郁症和其他社会、经济、人口和学术因素的关系。方法:对2018年UPTC 182名医学生进行观察性、分析性、横断面研究。应用Maslach职业倦怠量表-学生调查(MBI-SS),获得3个组成部分来确定SB阳性。这在Stata 15项目中与广义线性模型(GLM)进行交叉,用于抑郁症和其他社会、经济、人口和学术共变量。结果:182名被调查者中,女性占51.4%。中位年龄为21岁(20-23岁)。14%患有BS,其中48%患有抑郁症。在多元回归中,BS与较高的抑郁频率显著相关(RPa = 5.54;IC95%, 2.36 - -13.02;P 结论:BS与增加的抑郁和月底钱不够的感觉高度相关,但与烟草消费和作为女性呈负相关。应该发现这样的学生,为他们提供足够的学术支持。
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引用次数: 0
Subjective Cognitive and Communicative Complaints and Health-Related Quality of Life in Parkinson's Disease with and without Mild Cognitive Impairment 帕金森病患者的主观认知和交流抱怨以及与健康相关的生活质量(有无轻度认知障碍
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2023.11.004
Alberto Jaramillo-Jimenez , Yamile Bocanegra , Omar Buriticá , David Antonio Pineda Salazar , Leonardo Moreno Gómez , Carlos Andrés Tobón Quintero , Daniel Camilo Aguirre-Acevedo , Melissa Sierra Castrillon , Daniel Vasquez , Juan Esteban Velez-Hernandez , Miguel Germán Borda , Elkin García-Cifuentes , David Fernando Aguillón , Lucía Madrigal-Zapata , Dag Aarsland , Francisco Lopera

Introduction

Mild Cognitive Impairment (MCI) is common in Parkinson's Disease (PD). Few studies have compared the Health-Related Quality of Life (HRQoL) in patients with and without MCI due to PD (PD-MCI), and its correlation to patients’ subjective cognitive and communicative difficulties has not been explored.

Objective

We aimed to compare HRQoL in PD-MCI and PD without MCI (PD-nMCI), and explore its possible relationship to subjective cognitive and communicative complaints.

Methods

We included 29 PD-nMCI and 11 PD-MCI patients. The HRQoL was assessed with the Parkinson's Disease Questionnaire-39 (PDQ-39): its Cognition dimension was used as a measure of subjective cognitive complaints, its Communication dimension for subjective communicative complaints, and the summary index (PDQ-39 SI) as an indicator of HRQoL. Non-parametric partial correlations between the Cognition and Communication dimensions, and the adjusted PDQ-39 SI were conducted.

Results

PD-MCI patients had greater subjective cognitive and communicative complaints and worse HRQoL than PD-nMCI patients. In the PD-MCI group, both subjective cognitive and communicative complaints exhibited significant direct correlations with the adjusted HRQoL scores.

Conclusions

HRQoL seems to be affected in PD-MCI, and it might be influenced by greater subjective cognitive and communicative complaints. Including patient-reported outcome measures of HRQoL, and providing cognitive and speech rehabilitation, as well as psychotherapeutic strategies to face these deficits can enhance the patient-centred approach in PD.

导言轻度认知功能障碍(MCI)在帕金森病(PD)中很常见。我们旨在比较帕金森病轻度认知障碍患者(PD-MCI)和帕金森病轻度认知障碍患者(PD-nMCI)的生活质量(HRQoL),并探讨其与患者主观认知和交流困难的可能关系。我们使用帕金森病问卷-39(PDQ-39)对患者的 HRQoL 进行了评估:认知维度用于测量患者的主观认知症状,沟通维度用于测量患者的主观沟通症状,总结指数(PDQ-39 SI)作为 HRQoL 的指标。结果与 PD-nMCI 患者相比,PD-MCI 患者的主观认知和交流抱怨更多,HRQoL 更差。结论PD-MCI 患者的 HRQoL 似乎受到影响,而且可能受到主观认知和沟通主诉的影响。纳入患者报告的 HRQoL 结果测量,并提供认知和言语康复以及心理治疗策略来应对这些缺陷,可增强以患者为中心的 PD 治疗方法。
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引用次数: 0
“Learning to learn” in the Extended Inverted Classroom: An evaluation of the effects of interactive teaching on knowledge and cognitive regulation in medical students 扩展倒置课堂中“学会学习”:互动教学对医学生知识认知调节的影响
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.07.008
Luis Carlos Domínguez , Claudia Marcela Mora , Jorge Alberto Restrepo

Introduction

The evidence regarding the effects of the Inverted Classroom on students' metacognitive skills is limited. This study evaluates these effects on student perceptions about knowledge and cognitive regulation during a surgical course.

Methods

We measured student perceptions before and after a conventional Inverted Classroom in surgery using the Metacognitive Awareness Inventory. We evaluated the mean differences between the scores of the two measurements using Student’s t-test (p < 0.05), and the size of the effect on knowledge and cognitive regulation using Cohen’s d test (95%CI).

Results

A total of 158 students (pre-intervention) and 155 students (post-intervention) were included in the analysis. Significant differences were found (p < 0.05) in, as well as positive effects on, the students’ abilities to know their own learning (declarative knowledge) (d = 0.24; 95%CI, 0.02−0.47), to use learning strategies (procedural knowledge) (d = 0.19; 95%CI, –0.02 to 0.41) and to understand when and why to use these strategies (conditional knowledge) (d = 0.20; 95%CI, –0.01 to 0.42), in addition to the abilities to plan (d = 0.31; 95%CI, 0.09−0.53) and to evaluate their learning (d = 0.31; 95%CI, 0.08−0.53).

Conclusions

The Inverted Classroom has positive effects on metacognitive skills according to students’ perceptions. Further studies are required that compare these effects with other methodologies for teaching in the classroom and the workplace.

引言:关于翻转课堂对学生元认知技能影响的证据是有限的。本研究评估了这些对学生在外科课程中对知识和认知调节的感知的影响。方法:采用元认知意识量表测量学生在常规翻转课堂手术前后的认知。我们使用学生t检验(p )评估两项测量得分的平均差异。结果:共有158名学生(干预前)和155名学生(干预后)被纳入分析。结论:倒置课堂对学生的元认知技能有正向影响。需要进一步的研究将这些效果与课堂和工作场所的其他教学方法进行比较。
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引用次数: 0
Concern about COVID-19 infection and workload as predictors of psychological distress during the health emergency in Peruvian healthcare personnel 对COVID-19感染和工作量作为秘鲁卫生保健人员突发卫生事件期间心理困扰的预测因素的关注
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.06.015
Renzo Felipe Carranza Esteban , Oscar Javier Mamani-Benito , Dámaris Quinteros-Zúñiga , Rosa Farfán-Solís

Introduction

During the health emergency, there is concern about the mental health repercussions that Peruvian health workers, who represent the front line of care for COVID-19, may be experiencing.

Objective

To determine whether concern about COVID-19 and workloads predict psychological distress in healthcare workers.

Methods

Predictive study in which 367 workers (nurses, doctors, nursing assistants, obstetricians, dentists, psychologists, nutritionists, among others) from 12 health networks in the Puno region participated, selected through intentional non-probabilistic sampling. The data were collected via the Kessler Psychological Distress Scale, the COVID-19 Scale of Concern and the Workload Scale.

Results

It was found that there are no significant differences between men and women in psychological discomfort and concern about COVID-19 infection and workload. Furthermore, highly significant correlations were found between the study variables (P < .01). Multiple regression analysis showed an adequate adjustment for the model (F = 94.834; P < .001), where concern about COVID-19 (β = –0.436; P < .01) and workload (β = 0.239; P < .01) are variables that significantly predict psychological discomfort (adjusted R2 = 0.33).

Conclusions

Concern about COVID-19 and work overload predict psychological distress in health personnel in the Puno region.

导言:在突发卫生事件期间,人们担心作为COVID-19护理第一线的秘鲁卫生工作者可能会受到心理健康影响。目的:探讨对COVID-19的担忧和工作量是否能预测医护人员的心理困扰。方法:通过有意的非概率抽样,从普诺地区的12个卫生网络中选择367名工作人员(护士、医生、护理助理、产科医生、牙医、心理学家、营养学家等)参与预测研究。数据通过凯斯勒心理困扰量表、COVID-19关注量表和工作量量表收集。结果:男性和女性在心理不适、对COVID-19感染的担忧和工作量方面无显著差异。此外,研究变量之间存在高度显著的相关性(P 2 = 0.33)。结论:对COVID-19的担忧和超负荷工作预示着普诺地区卫生人员的心理困扰。
{"title":"Concern about COVID-19 infection and workload as predictors of psychological distress during the health emergency in Peruvian healthcare personnel","authors":"Renzo Felipe Carranza Esteban ,&nbsp;Oscar Javier Mamani-Benito ,&nbsp;Dámaris Quinteros-Zúñiga ,&nbsp;Rosa Farfán-Solís","doi":"10.1016/j.rcpeng.2021.06.015","DOIUrl":"10.1016/j.rcpeng.2021.06.015","url":null,"abstract":"<div><h3>Introduction</h3><p>During the health emergency, there is concern about the mental health repercussions that Peruvian health workers, who represent the front line of care for COVID-19, may be experiencing.</p></div><div><h3>Objective</h3><p>To determine whether concern about COVID-19 and workloads predict psychological distress in healthcare workers.</p></div><div><h3>Methods</h3><p>Predictive study in which 367 workers (nurses, doctors, nursing assistants, obstetricians, dentists, psychologists, nutritionists, among others) from 12 health networks in the Puno region participated, selected through intentional non-probabilistic sampling. The data were collected via the Kessler Psychological Distress Scale, the COVID-19 Scale of Concern and the Workload Scale.</p></div><div><h3>Results</h3><p>It was found that there are no significant differences between men and women in psychological discomfort and concern about COVID-19 infection and workload. Furthermore, highly significant correlations were found between the study variables (<em>P</em> &lt; .01). Multiple regression analysis showed an adequate adjustment for the model (F = 94.834; <em>P</em> &lt; .001), where concern about COVID-19 (β = –0.436; <em>P</em> &lt; .01) and workload (β = 0.239; <em>P</em> &lt; .01) are variables that significantly predict psychological discomfort (adjusted R<sup>2</sup> = 0.33).</p></div><div><h3>Conclusions</h3><p>Concern about COVID-19 and work overload predict psychological distress in health personnel in the Puno region.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 4","pages":"Pages 273-279"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138441798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with the intensity of anxiety and depression symptoms in health workers of two centres of reference for COVID 19 patient care in Antioquia, Colombia – A latent class analysis 哥伦比亚安蒂奥基亚两个COVID - 19患者护理参考中心卫生工作者焦虑和抑郁症状强度相关因素——潜在分类分析
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.09.002
Jesús David Bedoya Giraldo , Juliana Pulido Ángel , Jenny García Valencia , Daniel Camilo Aguirre Acevedo , Carlos Alberto Cardeño Castro

Objective

To classify the staff of two reference institutions for COVID-19 care in Antioquia according to the intensity of anxiety and depression symptoms, and to determine the factors associated with these classes.

Methods

Cross-sectional study in which the GAD-7, PHQ-9, fear of COVID-19, and the Copenhagen Burnout scale were used. Latent class analysis was performed to identify the classes, and the factors associated with these were determined using multinomial logistic regression.

Results

486 people participated. The three-class model had the best fit: class I with low scores on the scales; class II with mild degrees of anxiety and depression, and intermediate levels of fear of COVID-19 and perceived stress; and class III with moderate and severe degrees of anxiety, depression, and perceived stress. The factors associated with belonging to class III were age (OR = 0.94; 95%CI, 0.91−0.96), change of residence to avoid exposing relatives (OR = 4.01; 95%CI, 1.99–8.09), and a history of depressive disorder (OR = 3.10; 95%CI, 1.27–7.56), and anxiety (OR = 5.5; 95%CI, 2.36–12.90). Factors associated with class II were age (OR = 0.97; 95%CI, 0.95−0.99), history of depressive disorder (OR = 3.41; 95%CI, 1.60−7.25), living with someone at risk of death from COVID-19 (OR = 1.86; 95%CI, 1.19−2.91), family member being healthcare staff (OR = 1.58; 95%CI, 1.01−2.47), and change of residence to avoid exposing relatives (OR = 1.99; 95%CI, 1.11−3.59).

Conclusions

Three classes of participants were obtained, two of them with anxiety and depression symptoms. Younger age and a history of mental disorder were factors associated with the two classes of symptomatic patients; other factors may be causes or consequences of the symptoms.

目的:根据焦虑和抑郁症状的强度对安蒂奥基亚两家参比机构的COVID-19医护人员进行分类,并确定这些分类的相关因素。方法:采用横断面研究,采用GAD-7、PHQ-9、COVID-19恐惧和哥本哈根倦怠量表。进行潜在类别分析以确定类别,并使用多项逻辑回归确定与这些类别相关的因素。结果:486人参与。三级模型的拟合效果最好:第一类学生得分较低;ⅱ类患者有轻度焦虑、抑郁,对新冠病毒有中等程度的恐惧和感知压力;III类患者表现为中度和重度焦虑、抑郁和感知压力。与ⅲ类相关的因素是年龄(OR = 0.94;95%CI, 0.91-0.96),为避免暴露亲属而改变居住地(OR = 4.01;95%CI, 1.99-8.09)和抑郁症病史(OR = 3.10;95%CI, 1.27-7.56)和焦虑(OR = 5.5;95%可信区间,2.36 - -12.90)。II类相关因素为年龄(OR = 0.97;95%CI, 0.95-0.99)、抑郁病史(OR = 3.41;95%CI, 1.60-7.25),与有COVID-19死亡风险的人一起生活(OR = 1.86;95%CI, 1.19-2.91),家庭成员为医护人员(OR = 1.58;95%CI, 1.01-2.47),以及改变居住地以避免暴露亲属(OR = 1.99;95%可信区间,1.11 - -3.59)。结论:获得了三组参与者,其中两组有焦虑和抑郁症状。年龄较小和有精神障碍史是两类有症状患者的相关因素;其他因素可能是症状的原因或后果。
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引用次数: 0
Passive trauma 被动的创伤。
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.09.003
José Antonio Garciandía Imaz , Jeannette Samper Alum

Introduction

Wives of military personnel in action living on bases located in areas of armed conflict in Colombia before the peace negotiations with the Revolutionary Armed Forces of Colombia (FARC), were first-hand observers of the war, their husbands' participation in the war and the consequences and effects of the combat in which others participated.

Objective

To offer a hypothesis regarding these women's experience of direct trauma and characterise the dimensions of their experience as observers of the suffering of others.

Methods

Qualitative study and secondary discourse analysis in intentional snowball sampling of wives of military personnel (officers and chiefs) with whom semi-structured interviews were conducted.

Conclusions

Direct trauma is not the sole cause of psychosomatic and psychopathological consequences; the experience of constantly observing the suffering and deaths of others also generates a cumulative effect that can affect physical and mental health. This experience is called passive trauma.

引言:在与哥伦比亚革命武装力量(哥伦比亚革命武装力量)进行和平谈判之前,生活在哥伦比亚武装冲突地区基地的现役军事人员的妻子是战争、其丈夫参与战争以及其他人参与的战斗的后果和影响的第一手观察员。目的:提供一个关于这些女性直接创伤经历的假设,并描述她们作为他人痛苦观察者的经历的维度。方法:采用滚雪球抽样法对军队官兵(军官、参谋长)的妻子进行半结构化访谈,进行定性研究和二次话语分析。结论:直接创伤不是心身和精神病理后果的唯一原因;不断目睹他人痛苦和死亡的经历也会产生累积效应,影响身心健康。这种经历被称为被动创伤。
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引用次数: 0
Personality and Alzheimer's 人格和老年痴呆症。
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.06.017
Loida Camargo Camargo , María Cecilia Díaz Rodríguez , Norman Darío López Velásquez
{"title":"Personality and Alzheimer's","authors":"Loida Camargo Camargo ,&nbsp;María Cecilia Díaz Rodríguez ,&nbsp;Norman Darío López Velásquez","doi":"10.1016/j.rcpeng.2021.06.017","DOIUrl":"10.1016/j.rcpeng.2021.06.017","url":null,"abstract":"","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 4","pages":"Pages 270-272"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138441803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The need for complexity models in psychiatry: enactive approaches are knocking on the door of traditional psychiatry 精神病学需要复杂性模型:积极主动的方法正在叩开传统精神病学的大门
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2023.11.005
Hernando Santamaría-García
{"title":"The need for complexity models in psychiatry: enactive approaches are knocking on the door of traditional psychiatry","authors":"Hernando Santamaría-García","doi":"10.1016/j.rcpeng.2023.11.005","DOIUrl":"https://doi.org/10.1016/j.rcpeng.2023.11.005","url":null,"abstract":"","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 4","pages":"Page 269"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138550023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the neurocognitive profile of the children of parents with bipolar disorder and controls: A transnational cross-sectional study 双相情感障碍父母与对照组儿童神经认知特征的比较:一项跨国横断面研究。
Pub Date : 2023-10-01 DOI: 10.1016/j.rcpeng.2021.07.005
Sara Fernanda Restrepo-Mejía , Johanna Valencia-Echeverry , Juan Pablo Zapata-Ospina , Daniel Camilo Aguirre-Acevedo , Carlos Lopez-Jaramillo , Juan David Palacio-Ortiz

Introduction

Studies that have compared the cognitive alterations of the children of parents with bipolar disorder (CPBD) versus the children of control parents (CCP), present heterogeneous results due to the studies’ methodological differences, the age of the population studied, and the lack of standardisation of the measures used for the different neurocognitive domains. The objective was to compare the neurocognitive profile of CPBD versus CCP to observe if there are differences that could be proposed as possible endophenotypes of BD.

Results

A total of 107 individuals (51 CPBD, and 56 CCP) with ages between 6 and 16 (mean, 12.2 ± 2.80) years of age were evaluated. Seventy-four point five percent of the CPBD group had some disorder compared to 67.9% of the CCP group. Tests such as letter-F phonemic verbal fluency, letter-S phonemic verbal fluency, overall F-A-S phonemic verbal fluency, story recall and retrieval, and Wisconsin perseverative errors showed a difference with a small effect size, but with a high degree of uncertainty.

Conclusions

The CPBD did not have differences in their neurocognitive profile in comparison with CCP. Both groups have a high prevalence of psychopathology, which is a factor that could explain the lack of differences in neurocognitive performance.

导读:研究比较了双相情感障碍(CPBD)父母的孩子与正常父母(CCP)的孩子的认知改变,由于研究方法的差异,研究人群的年龄,以及不同神经认知领域使用的测量缺乏标准化,得出了不同的结果。目的是比较CPBD和CCP的神经认知特征,以观察是否存在可以作为bd可能的内表型的差异。结果:共评估了107例(51例CPBD, 56例CCP),年龄在6 ~ 16岁(平均12.2±2.80)岁。CPBD组中有75.5%的人患有某种疾病,而CCP组中这一比例为67.9%。诸如字母f音位语言流畅性、字母s音位语言流畅性、整体F-A-S音位语言流畅性、故事回忆和检索以及威斯康星持久性错误等测试显示了小效应量的差异,但具有高度的不确定性。结论:与CCP相比,CPBD在神经认知方面没有差异。两组人都有很高的精神病理学患病率,这是一个可以解释神经认知表现缺乏差异的因素。
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引用次数: 0
期刊
Revista Colombiana de psiquiatria (English ed.)
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