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HOW I DO IT: Breaking boundaries in surgical education by delivering expert feedback to residents anytime and anywhere. The LAPPCLINIC project. 我怎么做:通过随时随地向住院医生提供专家反馈,打破外科教育的界限。LAPPCLINIC项目。
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-09-12 DOI: 10.1016/j.sopen.2025.09.007
Diego Sanhueza R. MD , Cristián Jarry T. MD, MSc , Julián Varas C. MD, MSc

Objective

To describe LAPPCLINIC, an innovative web-based platform designed to enhance surgical education through remote and asynchronous feedback by video-analysis of residents' own surgical procedures.

Design

We provide a detailed description of the platform workflow, highlighting key features for enhancing surgical education.

Setting

An ongoing multicenter study involving seven surgical residency programs across Chile.

Participants

First-year surgical residents from seven different Chilean programs, with feedback provided by five surgeons, experienced in surgical education, who are beyond their learning curves in laparoscopic cholecystectomy and trained in structured quality-feedback delivery.

Conclusion

LAPPCLINIC implementation has shown strong resident acceptance and significantly higher evaluation of feedback quality compared to traditional OR-based teaching.
目的介绍一种创新的基于网络的平台LAPPCLINIC,该平台旨在通过对住院医生自身手术过程的视频分析,通过远程和异步反馈来加强外科教育。我们提供了平台工作流程的详细描述,突出了加强外科教育的关键功能。一项正在进行的多中心研究涉及智利的七个外科住院医师项目。参与者:来自智利7个不同项目的第一年外科住院医师,由5名外科医生提供反馈,他们在外科教育方面经验丰富,在腹腔镜胆囊切除术方面超出了他们的学习曲线,并接受了结构化质量反馈交付的培训。结论与传统的基于手术室的教学相比,实施lappclinic的住院医师接受度高,反馈质量评价显著提高。
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引用次数: 0
Prediction of mortality after esophagectomy: A comprehensive analysis of various risk scores in a national esophageal center 食管切除术后死亡率预测:国家食管中心各种风险评分的综合分析
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-08-16 DOI: 10.1016/j.sopen.2025.08.001
Ahmed Al-Mawsheki , Maximilian Bockhorn , Sorin Miftode , Fadl Alfarawan , Asem Al-Salemi , Catharina Fahrenkorg , Nader- El-Sourani

Background

Esophagectomy remains the cornerstone treatment for esophageal cancer but is associated with significant perioperative morbidity and mortality, even in specialized centers. Accurate preoperative risk assessment is crucial to improve patient outcomes, and various predictive models are available for risk stratification. This study aimed to validate and compare the performance of nine established predictive models in forecasting 30-day mortality following esophagectomy in a high-volume esophageal cancer center.

Methods

We retrospectively analyzed of 101 patients who underwent esophagectomy between January 2020 and December 2023 was performed. Clinicopathological characteristics and mortality data were obtained. The predictive accuracy of nine risk models, including the Esophageal-POSSUM (O-POSSUM), Charlson Comorbidity Index (Charlson), Postoperative Estimation of Risk (PER), and Fuchs scores, was assessed using logistic regression, Hosmer-Lemeshow tests for calibration, and the area under the receiver operating characteristic curve (AUC) for discrimination. Mann-Whitney U tests were used to evaluate significant differences between survivors and non-survivors.

Results

The 30-day mortality rate was 8.91 %. The O-POSSUM and Charlson scores demonstrated the highest predictive accuracy with AUCs of 0.832 and 0.806, respectively. The PER and Fuchs models also showed significant associations with mortality but with moderate predictive ability. Models such as the American Society of Anesthesiologists (ASA) and Philadelphia scores demonstrated limited predictive utility. Significant differences in predictive performance were noted across patient subgroups.

Conclusions

The O-POSSUM and Charlson scores were reliable tools for predicting 30-day mortality after esophagectomy. Other models require further validation and refinement. Tailoring risk assessment models in specific clinical settings may enhance their predictive accuracy and contribute to improved patient outcomes.
背景食管癌切除术仍是食管癌的基础治疗方法,但其围手术期发病率和死亡率较高,即使在专业中心也是如此。准确的术前风险评估对改善患者预后至关重要,各种预测模型可用于风险分层。本研究旨在验证和比较九种已建立的预测模型在预测食管癌大容量中心食管癌切除术后30天死亡率方面的表现。方法回顾性分析2020年1月至2023年12月行食管切除术的101例患者。获得临床病理特征和死亡率数据。9种风险模型,包括食道- possum (O-POSSUM)、Charlson共病指数(Charlson)、术后风险估计(PER)和Fuchs评分的预测准确性,采用logistic回归、Hosmer-Lemeshow检验进行校准,以及受试者工作特征曲线下面积(AUC)进行区分。使用Mann-Whitney U检验来评估幸存者和非幸存者之间的显著差异。结果30 d死亡率为8.91%。O-POSSUM和Charlson评分的预测准确率最高,auc分别为0.832和0.806。PER和Fuchs模型也显示出与死亡率的显著关联,但预测能力一般。美国麻醉师协会(ASA)和费城评分等模型显示出有限的预测效用。不同患者亚组在预测表现上存在显著差异。结论O-POSSUM和Charlson评分是预测食管切除术后30天死亡率的可靠工具。其他模型需要进一步验证和细化。在特定的临床环境中定制风险评估模型可以提高其预测的准确性,并有助于改善患者的预后。
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引用次数: 0
Impact of inflammatory biomarkers and surgical interventions on one-month recovery after rib fractures: A propensity-matched cohort study 炎症生物标志物和手术干预对肋骨骨折后一个月恢复的影响:一项倾向匹配的队列研究
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-11-03 DOI: 10.1016/j.sopen.2025.10.009
Xiaojiao Zhu , Jianwei Han , Chuan Long , Wenjun Cao , Suwei Xu , Yingding Ruan

Background

This study aims to assess the collective influence of inflammatory indicators and surgical interventions on the one-month postoperative recovery outcomes in patients with rib fractures.

Methods

A retrospective analysis involved 70 surgical and 278 non - surgical rib - fracture patients. Primary outcomes were thoracic complication incidence and post - discharge oral analgesic use at one month. Secondary outcomes included hospital stay length and total costs. We collected various data and conducted propensity score matching (1:2 ratio) to control for confounders, followed by multivariate analyses.

Results

After PSM (60 surgical vs. 117 non-surgical patients), surgical reduced hospital stay by 10.4 days (β = −10.36 days, 95 % confidence interval [95 % CI]: −16.03 to −4.70; P < 0.001), but increase in total costs by 30,808.80 CNY (P < 0.001). Pre-existing thoracic complications independently predicted higher one-month postoperative complications (OR[95 % CI] = 4.05 [1.08, 18.15]; P = 0.048), while comorbidities lowered risk (OR[95 %CI] = 0.29 [0.08, 0.89]; P = 0.043). Elevated systemic immune-inflammation index (SII) (Coef [95 % CI] = 528.03 [28.05, 1028.00]; P = 0.039) and neutrophil-to-lymphocyte ratio (NLR) (Coef[95 % CI] = 3.50 [0.62, 6.37]; P = 0.017) were positively correlated with Injury Severity Score (ISS). In surgical patients, a higher lymphocyte-to-monocyte ratio (LMR) independently predicted a lower likelihood of ongoing analgesic use at one month (OR[95 %CI] = 0.70 [0.46, 0.95]; P = 0.046).

Conclusion

Surgical rib - fracture stabilization shortens hospital stay but raises treatment costs. High SII and NLR, along with thoracic complications, are linked to post - op complications. LMR and HGB levels are associated with analgesic needs, which may aid in tailored pain management.
本研究旨在评估炎症指标和手术干预对肋骨骨折患者术后1个月恢复结果的总体影响。方法回顾性分析70例手术性和278例非手术性肋骨骨折患者的临床资料。主要结局是胸并发症发生率和出院后1个月口服镇痛药的使用情况。次要结局包括住院时间和总费用。我们收集了各种数据,并进行倾向得分匹配(1:2比例)以控制混杂因素,然后进行多变量分析。结果PSM术后(60例手术对117例非手术),手术使住院时间减少10.4天(β = - 10.36天,95%可信区间[95% CI]: - 16.03 ~ - 4.70; P < 0.001),但总费用增加30,808.80元(P < 0.001)。先前存在的胸部并发症独立预测较高的术后1个月并发症(OR[95% CI] = 4.05 [1.08, 18.15]; P = 0.048),而合并症降低风险(OR[95% CI] = 0.29 [0.08, 0.89]; P = 0.043)。全身免疫炎症指数(SII) (Coef[95% CI] = 528.03 [28.05, 1028.00]; P = 0.039)和中性粒细胞/淋巴细胞比值(NLR) (Coef[95% CI] = 3.50 [0.62, 6.37]; P = 0.017)升高与损伤严重程度评分(ISS)呈正相关。在手术患者中,较高的淋巴细胞/单核细胞比率(LMR)独立预测一个月后继续使用止痛药的可能性较低(OR[95% CI] = 0.70 [0.46, 0.95]; P = 0.046)。结论肋骨骨折手术稳定缩短了住院时间,但增加了治疗费用。高SII和NLR以及胸部并发症与术后并发症有关。LMR和HGB水平与镇痛需求有关,这可能有助于定制疼痛管理。
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引用次数: 0
Clinical and financial outcomes associated with gastrointestinal complications among patients with type B aortic dissection B型主动脉夹层患者胃肠道并发症的临床和经济预后
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-10-23 DOI: 10.1016/j.sopen.2025.10.006
Troy N. Coaston MSCR , Amulya Vadlakonda MD , Esteban Aguayo MD , Zihan Gao MHSc , Syed Shaheer Ali , Oh Jin Kwon MD , Peyman Benharash MD

Background

Gastrointestinal complications (GIC) are an uncommon but serious sequelae of type B aortic dissection (TBAD), potentially contributing to increased mortality and healthcare resource utilization. Limited studies have characterized these complications among TBAD patients. The present work sought to evaluate the clinical and financial implications of GIC and identifies factors associated with their development.

Methods

All hospitalizations entailing a primary diagnosis of TBAD were identified in the 2016–2020 Nationwide Readmissions Database. Patients were stratified into those who developed GIC and those who did not. Outcomes included in-hospital mortality, length of stay (LOS), hospitalization costs, and the need for abdominal surgery. Multivariable logistic and linear regressions were employed to assess associations between patient, facility, and treatment factors with clinical and financial outcomes.

Results

Of 24,927 TBAD hospitalizations, 2.5 % developed GIC, and 24.0 % of these cases required an abdominal procedure. Patients with GIC were younger (median 61 vs. 67 years; p < 0.001), more commonly male (67.4 vs. 56.6 %; p < 0.001), and more likely to have Medicaid insurance (20.9 vs. 12.5 %; p < 0.001). GIC were independently associated with increased odds of in-hospital mortality (adjusted odds ratio 4.54; 95 % CI 3.41–6.04), greater LOS (β 5.80 days; 95 % CI 3.88–7.72), and increased costs (β $41,000; 95 % CI $31000–51,000).

Conclusions

GIC in TBAD patients was associated with substantial clinical and financial burdens. Further study of early identification and targeted interventions is warranted to mitigate these complications and optimize resource utilization in this high-risk population.
背景:胃肠道并发症(GIC)是B型主动脉夹层(TBAD)的一种罕见但严重的后遗症,可能导致死亡率和医疗资源利用率的增加。有限的研究描述了TBAD患者的这些并发症。目前的工作旨在评估GIC的临床和财务影响,并确定与其发展相关的因素。方法在2016-2020年全国再入院数据库中确定所有初步诊断为TBAD的住院病例。患者被分为有GIC的和没有GIC的两组。结果包括住院死亡率、住院时间(LOS)、住院费用和腹部手术的需要。采用多变量逻辑回归和线性回归来评估患者、设施和治疗因素与临床和财务结果之间的关系。结果在24,927例TBAD住院患者中,2.5%发展为GIC,其中24.0%需要腹部手术。GIC患者更年轻(中位年龄61岁vs. 67岁;p < 0.001),更常见的是男性(67.4% vs. 56.6%; p < 0.001),更有可能拥有医疗补助保险(20.9% vs. 12.5%; p < 0.001)。GIC与住院死亡率增加的几率(校正优势比4.54;95% CI 3.41-6.04)、更大的LOS (β 5.80天;95% CI 3.88-7.72)和成本增加(β 41,000美元;95% CI 31,000 - 51,000美元)独立相关。结论TBAD患者的gic与巨大的临床和经济负担相关。有必要进一步研究早期识别和有针对性的干预措施,以减轻这些并发症,并优化这一高危人群的资源利用。
{"title":"Clinical and financial outcomes associated with gastrointestinal complications among patients with type B aortic dissection","authors":"Troy N. Coaston MSCR ,&nbsp;Amulya Vadlakonda MD ,&nbsp;Esteban Aguayo MD ,&nbsp;Zihan Gao MHSc ,&nbsp;Syed Shaheer Ali ,&nbsp;Oh Jin Kwon MD ,&nbsp;Peyman Benharash MD","doi":"10.1016/j.sopen.2025.10.006","DOIUrl":"10.1016/j.sopen.2025.10.006","url":null,"abstract":"<div><h3>Background</h3><div>Gastrointestinal complications (GIC) are an uncommon but serious sequelae of type B aortic dissection (TBAD), potentially contributing to increased mortality and healthcare resource utilization. Limited studies have characterized these complications among TBAD patients. The present work sought to evaluate the clinical and financial implications of GIC and identifies factors associated with their development.</div></div><div><h3>Methods</h3><div>All hospitalizations entailing a primary diagnosis of TBAD were identified in the 2016–2020 Nationwide Readmissions Database. Patients were stratified into those who developed GIC and those who did not. Outcomes included in-hospital mortality, length of stay (LOS), hospitalization costs, and the need for abdominal surgery. Multivariable logistic and linear regressions were employed to assess associations between patient, facility, and treatment factors with clinical and financial outcomes.</div></div><div><h3>Results</h3><div>Of 24,927 TBAD hospitalizations, 2.5 % developed GIC, and 24.0 % of these cases required an abdominal procedure. Patients with GIC were younger (median 61 vs. 67 years; <em>p</em> &lt; 0.001), more commonly male (67.4 vs. 56.6 %; p &lt; 0.001), and more likely to have Medicaid insurance (20.9 vs. 12.5 %; p &lt; 0.001). GIC were independently associated with increased odds of in-hospital mortality (adjusted odds ratio 4.54; 95 % CI 3.41–6.04), greater LOS (β 5.80 days; 95 % CI 3.88–7.72), and increased costs (β $41,000; 95 % CI $31000–51,000).</div></div><div><h3>Conclusions</h3><div>GIC in TBAD patients was associated with substantial clinical and financial burdens. Further study of early identification and targeted interventions is warranted to mitigate these complications and optimize resource utilization in this high-risk population.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Pages 43-48"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of operative approach with adverse events following hepatic resections 肝切除术后手术入路与不良事件的关系
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-09-08 DOI: 10.1016/j.sopen.2025.09.004
Arjun Chaturvedi , Esteban Aguayo , Oh. Jin Kwon , Kevin Tabibian , Barzin Badiee , Saad Mallick , Daniel Tabibian , Peyman Benharash

Background

Despite growing use of minimally invasive surgery (MIS) for hepatocellular carcinoma (HCC), contemporary national data contrasting MIS with open hepatectomy are sparse.

Methods

Adults (≥18 y) undergoing hepatectomy for HCC in the American College of Surgeons National Surgical Quality Improvement Program (2015–2022) were studied. MIS (laparoscopic or robotic) resections were compared with open operations. Entropy balancing harmonized covariates, and multivariable logistic or linear models produced adjusted odds ratios (AOR) for major adverse events (MAE; composite of mortality and serious complications), liver-specific complications, and 30-day readmission.

Results

Among 5832 hepatectomies, 27.0 % were MIS, rising from 18.8 % in 2015 to 36.1 % in 2022 (p < 0.001). After adjustment, MIS was associated with markedly lower odds of MAE (AOR 0.36, 95 % CI 0.29–0.46), postoperative liver failure (AOR 0.34, 0.20–0.58), bile leak (AOR 0.49, 0.28–0.89), need for invasive intervention (AOR 0.29, 0.18–0.47), and 30-day readmission (AOR 0.61, 0.44–0.86). In the subset undergoing major resections, MIS retained protective associations for MAE (AOR 0.26, 0.15–0.46) and readmission (AOR 0.28, 0.11–0.80).

Conclusions

In a large, contemporary U.S. cohort, MIS hepatectomy was independently associated with fewer perioperative complications, liver-specific adverse events, and readmissions compared with open surgery—even for major resections. These findings support continued expansion of minimally invasive hepatectomy and targeted training to extend its benefits to appropriately selected patients with resectable HCC.
背景:尽管微创手术(MIS)在肝细胞癌(HCC)治疗中的应用越来越多,但目前国内对比微创手术与开放肝切除术的数据很少。方法研究美国外科医师学会国家手术质量改进计划(2015-2022)中接受HCC肝切除术的成人(≥18岁)。MIS(腹腔镜或机器人)切除与开放手术比较。熵平衡协调协变量,多变量逻辑或线性模型产生了主要不良事件(MAE;死亡率和严重并发症的组合)、肝脏特异性并发症和30天再入院的调整优势比(AOR)。结果5832例肝切除术中,MIS占27.0%,由2015年的18.8%上升至2022年的36.1% (p < 0.001)。调整后,MIS与MAE (AOR 0.36, 95% CI 0.29 - 0.46)、术后肝衰竭(AOR 0.34, 0.20-0.58)、胆漏(AOR 0.49, 0.28-0.89)、需要侵入性干预(AOR 0.29, 0.18-0.47)和30天再入院(AOR 0.61, 0.44-0.86)的发生率显著降低相关。在接受主要切除术的亚组中,MIS保留了MAE (AOR 0.26, 0.15-0.46)和再住院(AOR 0.28, 0.11-0.80)的保护性关联。结论:在一项大型的美国当代队列研究中,与开放式手术相比,MIS肝切除术的围手术期并发症、肝脏特异性不良事件和再入院率均较低,即使是大切除手术。这些发现支持继续扩大微创肝切除术和有针对性的培训,以扩大其对适当选择的可切除HCC患者的益处。
{"title":"Association of operative approach with adverse events following hepatic resections","authors":"Arjun Chaturvedi ,&nbsp;Esteban Aguayo ,&nbsp;Oh. Jin Kwon ,&nbsp;Kevin Tabibian ,&nbsp;Barzin Badiee ,&nbsp;Saad Mallick ,&nbsp;Daniel Tabibian ,&nbsp;Peyman Benharash","doi":"10.1016/j.sopen.2025.09.004","DOIUrl":"10.1016/j.sopen.2025.09.004","url":null,"abstract":"<div><h3>Background</h3><div>Despite growing use of minimally invasive surgery (MIS) for hepatocellular carcinoma (HCC), contemporary national data contrasting MIS with open hepatectomy are sparse.</div></div><div><h3>Methods</h3><div>Adults (≥18 y) undergoing hepatectomy for HCC in the American College of Surgeons National Surgical Quality Improvement Program (2015–2022) were studied. MIS (laparoscopic or robotic) resections were compared with open operations. Entropy balancing harmonized covariates, and multivariable logistic or linear models produced adjusted odds ratios (AOR) for major adverse events (MAE; composite of mortality and serious complications), liver-specific complications, and 30-day readmission.</div></div><div><h3>Results</h3><div>Among 5832 hepatectomies, 27.0 % were MIS, rising from 18.8 % in 2015 to 36.1 % in 2022 (<em>p</em> &lt; 0.001). After adjustment, MIS was associated with markedly lower odds of MAE (AOR 0.36, 95 % CI 0.29–0.46), postoperative liver failure (AOR 0.34, 0.20–0.58), bile leak (AOR 0.49, 0.28–0.89), need for invasive intervention (AOR 0.29, 0.18–0.47), and 30-day readmission (AOR 0.61, 0.44–0.86). In the subset undergoing major resections, MIS retained protective associations for MAE (AOR 0.26, 0.15–0.46) and readmission (AOR 0.28, 0.11–0.80).</div></div><div><h3>Conclusions</h3><div>In a large, contemporary U.S. cohort, MIS hepatectomy was independently associated with fewer perioperative complications, liver-specific adverse events, and readmissions compared with open surgery—even for major resections. These findings support continued expansion of minimally invasive hepatectomy and targeted training to extend its benefits to appropriately selected patients with resectable HCC.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Pages 1-6"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145050534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated right hepatic duct dilation – Type VI of Mirizzi syndrome? 孤立性右肝管扩张- Mirizzi综合征的VI型?
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-11-29 DOI: 10.1016/j.sopen.2025.11.006
Longchang Chen , Yan Sun , Quanda Liu
{"title":"Isolated right hepatic duct dilation – Type VI of Mirizzi syndrome?","authors":"Longchang Chen ,&nbsp;Yan Sun ,&nbsp;Quanda Liu","doi":"10.1016/j.sopen.2025.11.006","DOIUrl":"10.1016/j.sopen.2025.11.006","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Pages 98-100"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145693452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board Page 编委会页面
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-12-11 DOI: 10.1016/S2589-8450(25)00103-4
{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2589-8450(25)00103-4","DOIUrl":"10.1016/S2589-8450(25)00103-4","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Page i"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenteric inclusion in Crohn's disease surgery: Promising breakthrough or tempest in a teapot? An updated meta-analysis 克罗恩病手术中的肠系膜包涵术:有希望的突破还是茶壶里的风暴?更新后的元分析
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-11-03 DOI: 10.1016/j.sopen.2025.10.010
Mohamed Maatouk MD, MS , Mohamed Ben Khalifa MD , Nada Essid MD , Aymen Mabrouk MD , Mariem Nouira MD , Moez Boudokhane MD , Mounir Ben Moussa MD, PhD

Background

Recently, renewed concern has been centered on the role of the mesentery in the development of Crohn's disease (CD). However, there are minimal data supporting the extended mesenteric excision (EME), which may lead to reticence in the adoption of this surgical option. This systematic review and meta-analysis aimed to compare the post-operative outcomes in patients undergoing EME vs limited mesenteric excision (LME) for CD.

Methods

We conducted a systematic search from January 2018 to January 2025 for studies reporting outcomes in patients undergoing EME compared with LME for CD. A pooled meta-analysis was performed. The risk of bias was examined using the ROBINS-I v2 and RoB2 tool.

Results

Nine studies were included in final analysis, comprising two randomized controlled trials, enrolling a total of 4823 patients. Definitions of EME differ, with some studies preserving the ileocolic trunk and others resecting the mesentery with proximal ligation. No significant difference in surgical or endoscopic recurrence was observed between EME and LME. Concerning secondary outcomes, including overall morbidity, intra-abdominal abscess, anastomotic leak and hospital stay, the two groups showed no significant differences.

Conclusions

EME appears as safe as the LME in terms of morbidity, but does not significantly reduce surgical or endoscopic recurrence. Due to the absence of a precise definition of the EME procedure in CD and the need of further high-quality research, the approach of EME still lacks sufficient validation and cannot be broadly recommended for routine clinical practice.
最近,人们重新关注肠系膜在克罗恩病(CD)发展中的作用。然而,支持扩展肠系膜切除(EME)的数据很少,这可能导致对采用这种手术选择的保留。本系统综述和荟萃分析旨在比较EME与有限肠系膜切除(LME)治疗CD患者的术后结果。方法我们从2018年1月至2025年1月对报道EME与LME治疗CD患者结果的研究进行了系统检索。使用ROBINS-I v2和RoB2工具检查偏倚风险。结果纳入9项研究,包括2项随机对照试验,共纳入4823例患者。EME的定义不同,一些研究保留回肠结肠干,而另一些研究切除肠系膜并近端结扎。EME和LME在手术或内镜下复发方面无显著差异。在总体发病率、腹内脓肿、吻合口漏、住院时间等次要结局方面,两组无显著差异。结论在发病率方面,seme与LME一样安全,但没有显著减少手术或内镜下复发。由于缺乏对CD中EME程序的精确定义和进一步高质量研究的需要,EME方法仍然缺乏足够的验证,不能广泛推荐用于常规临床实践。
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引用次数: 0
Health-related quality of life after HPB surgery HPB手术后与健康相关的生活质量
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-10-30 DOI: 10.1016/j.sopen.2025.10.007
Victor M. Zaydfudim
{"title":"Health-related quality of life after HPB surgery","authors":"Victor M. Zaydfudim","doi":"10.1016/j.sopen.2025.10.007","DOIUrl":"10.1016/j.sopen.2025.10.007","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Pages 63-64"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of malnutrition with clinical and financial outcomes of traumatic injuries in older adults: A national retrospective analysis 营养不良与老年人创伤性损伤的临床和财务结果的关联:一项全国回顾性分析
IF 1.7 Q3 SURGERY Pub Date : 2025-12-01 Epub Date: 2025-09-17 DOI: 10.1016/j.sopen.2025.09.008
Troy N. Coaston MSCR , Konmal Ali BS , Amulya Vadlakonda MD , Deep J. Mehta , Sara Sakowitz MD, MPH , Dariush Yalzadeh BS , Areti Tillou MD , Peyman Benharash MD , on behalf of the Academic Trauma Research Consortium (ATRIUM)

Background

Malnutrition is an often underrecognized condition among older adults and carries significant relevance among patients hospitalized with traumatic injuries. The present study aimed to evaluate the association of malnutrition with clinical and financial outcomes among older adult patients admitted with external trauma.

Study design

This was a retrospective cohort study of the 2016–2021 National Inpatient Sample including older adults (≥65 years) hospitalized with traumatic injuries. Patients were stratified by nutritional status (Malnourished and Non-Malnourished). Risk-adjusted logistic and linear regression models were constructed to evaluate the association of malnutrition with outcomes including inpatient mortality, clinical complications, and hospitalization costs.

Results

Of 6,587,907 older adults admitted with traumatic injuries, 7.5 % had malnutrition. The prevalence of malnutrition rose from 5.8 % to 8.6 % over the study period (nptrend<0.001). Patients with malnutrition were more commonly of the lowest income quartile (25.5 vs 24.5 %), non-White (19.4 vs 16.9 %), and male (41.3 vs 39.1 %, all p < 0.001). Following risk-adjustment, malnutrition was linked with increased odds of inpatient mortality (Adjusted Odds Ratio [AOR] 1.92, 95 % Confidence Interval [CI] 1.86–1.98) and infectious complications (AOR 2.30, 95 % CI 2.25–2.35) as well as greater inpatient costs (β + $7400, 95 % CI $7100-7600).

Conclusion

Malnutrition among older adults is associated with poorer clinical outcomes and increased financial burden. Rising prevalence and significant disparities underscore the need for increased screening and culturally relevant nutritional interventions to promote quality, equity, and sustainability in trauma care.
背景:营养不良在老年人中是一种常被忽视的疾病,在创伤性损伤住院患者中具有重要的相关性。本研究旨在评估老年外伤患者营养不良与临床和财务结果的关系。这是一项2016-2021年全国住院患者样本的回顾性队列研究,包括因创伤性损伤住院的老年人(≥65岁)。根据营养状况(营养不良和非营养不良)对患者进行分层。构建风险校正logistic和线性回归模型来评估营养不良与住院死亡率、临床并发症和住院费用等结果的关系。结果6587907例老年人外伤住院患者中,营养不良占7.5%。在研究期间,营养不良发生率从5.8%上升到8.6% (nptrend<0.001)。营养不良的患者更常见于最低收入四分位数(25.5%对24.5%)、非白人(19.4%对16.9%)和男性(41.3%对39.1%,均p <; 0.001)。风险调整后,营养不良与住院死亡率增加(调整优势比[AOR] 1.92, 95%可信区间[CI] 1.86-1.98)和感染并发症(AOR 2.30, 95% CI 2.25-2.35)以及住院费用增加(β + $7400, 95% CI $7100-7600)有关。结论老年人营养不良与临床预后差、经济负担增加有关。不断上升的患病率和显著的差异强调需要增加筛查和与文化相关的营养干预措施,以促进创伤护理的质量、公平性和可持续性。
{"title":"The association of malnutrition with clinical and financial outcomes of traumatic injuries in older adults: A national retrospective analysis","authors":"Troy N. Coaston MSCR ,&nbsp;Konmal Ali BS ,&nbsp;Amulya Vadlakonda MD ,&nbsp;Deep J. Mehta ,&nbsp;Sara Sakowitz MD, MPH ,&nbsp;Dariush Yalzadeh BS ,&nbsp;Areti Tillou MD ,&nbsp;Peyman Benharash MD ,&nbsp;on behalf of the Academic Trauma Research Consortium (ATRIUM)","doi":"10.1016/j.sopen.2025.09.008","DOIUrl":"10.1016/j.sopen.2025.09.008","url":null,"abstract":"<div><h3>Background</h3><div>Malnutrition is an often underrecognized condition among older adults and carries significant relevance among patients hospitalized with traumatic injuries. The present study aimed to evaluate the association of malnutrition with clinical and financial outcomes among older adult patients admitted with external trauma.</div></div><div><h3>Study design</h3><div>This was a retrospective cohort study of the 2016–2021 National Inpatient Sample including older adults (≥65 years) hospitalized with traumatic injuries. Patients were stratified by nutritional status (<em>Malnourished</em> and <em>Non-Malnourished</em>). Risk-adjusted logistic and linear regression models were constructed to evaluate the association of malnutrition with outcomes including inpatient mortality, clinical complications, and hospitalization costs.</div></div><div><h3>Results</h3><div>Of 6,587,907 older adults admitted with traumatic injuries, 7.5 % had malnutrition. The prevalence of malnutrition rose from 5.8 % to 8.6 % over the study period (nptrend&lt;0.001). Patients with malnutrition were more commonly of the lowest income quartile (25.5 vs 24.5 %), non-White (19.4 vs 16.9 %), and male (41.3 vs 39.1 %, all <em>p</em> &lt; 0.001). Following risk-adjustment, malnutrition was linked with increased odds of inpatient mortality (Adjusted Odds Ratio [AOR] 1.92, 95 % Confidence Interval [CI] 1.86–1.98) and infectious complications (AOR 2.30, 95 % CI 2.25–2.35) as well as greater inpatient costs (β + $7400, 95 % CI $7100-7600).</div></div><div><h3>Conclusion</h3><div>Malnutrition among older adults is associated with poorer clinical outcomes and increased financial burden. Rising prevalence and significant disparities underscore the need for increased screening and culturally relevant nutritional interventions to promote quality, equity, and sustainability in trauma care.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"28 ","pages":"Pages 13-18"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Surgery open science
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