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Multiple Organ Dysfunction Following Aspiration of Maternal Blood 母体吸血后多器官功能障碍
Pub Date : 2012-01-24 DOI: 10.5580/2edf
S. Patrick, D. Kershaw, M. Attar
We describe the case of a term newborn with multiple organs dysfunction, including respiratory distress, acute renal failure, and hypotension following aspiration of maternal blood around the time of birth. We also discuss potential mechanisms for local (pulmonary) and systemic effects of blood aspiration.
我们描述的情况下,足月新生儿多器官功能障碍,包括呼吸窘迫,急性肾功能衰竭,低血压后吸入母体血液在出生的时候。我们还讨论了局部(肺)和全身吸血效应的潜在机制。
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引用次数: 1
Concurrent use of metered dose inhalers without spacer and dry powder inhalers by asthmatic children adversely affect proper inhalation technique. 哮喘患儿同时使用无间隔剂的计量吸入器和干粉吸入器对正确的吸入技术有不利影响。
Pub Date : 2011-06-14 DOI: 10.5580/2546
Saad Alotaibi, Walid M Hassan, Hashim Alhashimi

Asthma is a common chronic disease of children. A good control of symptoms will improve quality of patient life. Inhalation technique is an important aspect in the management of asthma. The better the inhalation technique the better the lung deposition of asthma therapy especially inhaled corticosteroids. This will lead to better control of symptoms and improve adherence to treatment. In the following study the inhalation technique of asthma devices were compared using inhalation technique score system. The asthma devices studied were metered dose inhalers (pressurized MDI) without spacers and dry powder inhalers (DPI). The hypothesis studied was that the inhalation technique score of dry powder inhalers will be adversely affected with concurrent use of metered dose inhalers without spacers.

哮喘是儿童常见的慢性疾病。对症状的良好控制将提高患者的生活质量。吸入技术是哮喘治疗的一个重要方面。吸入技术越好,哮喘治疗的肺部沉积越好,尤其是吸入皮质类固醇。这将有助于更好地控制症状并提高对治疗的依从性。在接下来的研究中,使用吸入技术评分系统对哮喘设备的吸入技术进行了比较。所研究的哮喘设备是无间隔物的计量吸入器(加压MDI)和干粉吸入器(DPI)。所研究的假设是,同时使用不含间隔物的计量吸入器会对干粉吸入器的吸入技术评分产生不利影响。
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引用次数: 8
Pediatricians Take On Oral Health Care Of Children 儿科医生负责儿童的口腔保健
Pub Date : 2010-12-31 DOI: 10.5580/2969
M. Virdi, M. Kaur, S. Mittal
Objective - To find the knowledge of pediatrician regarding preventive dental care in National Capital Territory of Delhi. MethodThis study was designed as a telephone survey. Phone numbers were retrieved from the local classified lists. Fifteen pediatricians from each district were randomly selected. Identified practicing pediatricians were called up and interviews sought. Results- Among the pediatricians interviewed 30 (33.70%)asked the patient to be taken to a dentist for a routine checkup ,whereas 59(66.26%) asked for a dental check up only in case the patient reported any dental problem. 42(47.19%) pediatricians knew about the availability of specialized branch of dentistry dealing with oral health care of children. ConclusionThe ultimate success of preventive dentistry is very much dependent upon the knowledge and function of the medical group concerned with children. Therefore it is of prime importance that the knowledge of pediatrician regarding preventive dental care be known and if need be enhanced regularly.
目的-了解德里国家首都地区儿科医生关于预防性牙科保健的知识。方法本研究采用电话调查方式。从当地的分类名单中检索到电话号码。每个地区随机抽取15名儿科医生。已确定的执业儿科医生被召集起来并进行访谈。结果:受访儿科医生中,30名(33.70%)要求患者进行常规牙科检查,59名(66.26%)要求仅在患者报告有牙齿问题时才进行牙科检查。42名(47.19%)儿科医生了解儿童口腔保健的牙科专科的可获得性。结论预防牙科的最终成功在很大程度上取决于儿童医疗群体的知识和功能。因此,儿科医生关于预防性牙科保健的知识是至关重要的,如果需要定期加强。
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引用次数: 7
Analysis of distal airway pressure changes in a simulation model of continuous positive airway pressure (CPAP). 持续气道正压通气(CPAP)模拟模型中远端气道压力变化分析。
Pub Date : 2010-12-31 DOI: 10.5580/192b
A. Orozco-gutierrez, Rosa María Estrada-Velazquez, Cesar Gil-Rosales
Background: Nasal continuous positive airway pressure (CPAP) is commonly used to treat respiratory failure in newborns with excellent results; however, pneumothorax is frequently reported, varying in frequency from 1.4% to 10.3%.Methods: In this study, we used a lung simulator to determine the cause of this variability by measuring the pressure in the CPAP system and in the interior of one balloon to simulate the lung, with repeat measurements with the nasal prongs sealed and unsealed. In addition, crying was simulated by blowing through a hole that simulated the mouth.Results: We found that when the nasal prongs were used, unsealed simulator distension existed. However, the pressure remained at zero when the nostrils were sealed, indicating that the pressure inside the simulated lung was equal to that inside the system. Simulated crying increased the pressure 4-fold.Conclusions: We conclude that the seal in the nostrils is a factor for the effectiveness of the procedure and increases the risk of pneumothorax, as well as alter the results of studies on nasal CPAP. Nostril seals should be considered for future studies on the efficacy and safety of nasal CPAP.
背景:鼻持续气道正压通气(CPAP)是治疗新生儿呼吸衰竭的常用方法,效果良好;然而,气胸经常被报道,频率从1.4%到10.3%不等。方法:在本研究中,我们使用肺模拟器来确定这种变异的原因,通过测量CPAP系统和一个气球内部的压力来模拟肺,并在鼻尖密封和打开时重复测量。此外,通过一个模拟嘴的孔吹气来模拟哭泣。结果:我们发现,当使用鼻尖时,存在非密封的模拟器膨胀。然而,当鼻孔被封闭时,压力保持为零,这表明模拟肺内的压力等于系统内的压力。模拟哭泣使压力增加了4倍。结论:我们的结论是,鼻孔的密封是影响手术效果的一个因素,增加了气胸的风险,并改变了鼻腔CPAP的研究结果。在进一步研究鼻腔CPAP的有效性和安全性时应考虑鼻腔密封。
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引用次数: 1
Prevalence Of Overweight/Obesity In School-Aged Children From Celaya, Guanajuato, Mexico, And Its Association With Arterial Hypertension: A Cross-Sectional Study. 墨西哥瓜纳华托州塞拉亚市学龄儿童超重/肥胖患病率及其与动脉高血压的关系:一项横断面研究
Pub Date : 2010-12-31 DOI: 10.5580/a78
N. Padilla-Raygoza, Laura Ruiz-Paloalto, R. D. Guerrero, Caitlin F. Canfield
Introduction. Obesity represents a major public health threat due to the high incidence of chronic disease in persons who are obese. Objective: to determine the prevalence of overweight/obesity in school age children in Celaya, Mexico, and its association with arterial hypertension. The protocol for this study was reviewed and approved by the Research and Bioethics Committee at the School of Nursing and Obstetrics at the University of Guanajuato. Materials and methods. The study is a cross-sectional, analytic, comparative, and community-based. Population: students enrolled in public elementary schools in Celaya, Guanajuato, Mexico. Inclusion criteria: both male and female children eight years of age and older were enrolled in the study given that their parents signed an informed consent, and that they assented to participate. Male and female children ages six and seven were also included in the study if their parents signed the informed consent. Exclusion criteria: children younger than six years of age, children who did not assent to participate in the study, children whose parents did not sign the informed consent. Sample: We randomized select four elementary schools in Celaya; in them, we invited parents and children to participate in the study. We measured age, gender, weight, height, Body Mass Index (BMI) and arterial tension. Outcomes were: not overweight: children at or below the 74th percentile of the CDC’s 2000 BMI curve; overweight/obese: children at or above the 75th BMI percentile. Hypertension was defined as having arterial tension above the 95th percentile given height, age, and gender. Statistical analysis. Chi-squared and Odds Ratio tests were performed to assess the association between overweight/obesity and arterial hypertension. Results. Our final sample included 301 children. The prevalence of overweight/obesity in our sample was 66.11% (199/301), while the prevalence of arterial hypertension was 7.97% (24/301). A Chi-squared test resulted in X = 3.45 df 1 p=0.06 when testing the association between overweight/obesity and arterial hypertension; the Odds Ratio was OR= 2.74 CI95%=0.90 to 8.30.Discussion. The prevalence of overweight/obesity in elementary school children was higher than we had expected to find. We also conclude that overweight/obesity and arterial hypertension are associated within this population.
介绍。肥胖是一个主要的公共卫生威胁,因为肥胖人群中慢性病的发病率很高。目的:确定墨西哥塞拉亚学龄儿童超重/肥胖的患病率及其与动脉高血压的关系。本研究的方案由瓜纳华托大学护理与产科学院研究与生物伦理委员会审查并批准。材料和方法。该研究采用横断面、分析、比较和社区为基础的方法。人口:在墨西哥瓜纳华托州塞拉亚公立小学就读的学生。纳入标准:八岁及以上的男女儿童均被纳入研究,前提是他们的父母签署了知情同意书,并且他们同意参与研究。6岁和7岁的男女儿童也包括在研究中,如果他们的父母签署了知情同意书。排除标准:6岁以下儿童、不同意参加研究的儿童、父母未签署知情同意书的儿童。样本:我们随机选择塞拉亚的四所小学;其中,我们邀请家长和孩子参与研究。我们测量了年龄、性别、体重、身高、身体质量指数(BMI)和动脉张力。结果是:不超重;儿童在或低于CDC 2000年BMI曲线的第74百分位;超重/肥胖:体重指数在第75百分位或以上的儿童。高血压被定义为在给定身高、年龄和性别的情况下,动脉张力高于第95百分位数。统计分析。采用卡方检验和优势比检验来评估超重/肥胖与动脉高血压之间的关系。结果。我们的最终样本包括301名儿童。我们的样本中超重/肥胖患病率为66.11%(199/301),动脉高血压患病率为7.97%(24/301)。在检验超重/肥胖与高血压之间的关系时,卡方检验的结果为X = 3.45 df 1 p=0.06;比值比OR= 2.74, 95%=0.90 ~ 8.30。小学生超重/肥胖的流行率比我们预期的要高。我们还得出结论,超重/肥胖和动脉高血压在这一人群中是相关的。
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引用次数: 0
Dentinogenesis Imperfecta – “A Hereditary Developmental Disturbance of Dentin” 牙本质发育不全-一种遗传性牙本质发育障碍
Pub Date : 2010-12-31 DOI: 10.5580/b15
Bajaj Neeti
Dentinogenesis Imperfecta (DGI) is a genetic disorder of tooth development inherited in an autosomal, dominant way, characterized by the presence of translucent or opalescent dentin, resulting in discoloration (amber-like, bluish grey color) of the teeth. It is a mesodermal defect wherein the dental papilla of either or both the primary and secondary dentition is abnormal. This paper describes the dental findings in a family where the father (33 year old) and the son (3 year old) both showed the characteristic dental features of DGI I.
牙本质发育不全(DGI)是一种以常染色体显性遗传方式遗传的牙齿发育遗传性疾病,其特征是牙本质呈半透明或乳白色,导致牙齿变色(琥珀色,蓝灰色)。这是一种中胚层缺陷,其中一种或两种牙列的乳突都异常。本文描述了一个家庭的牙齿发现,父亲(33岁)和儿子(3岁)都表现出典型的DGI I的牙齿特征。
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引用次数: 1
An Insight Into The Spectrum Of Apert Syndrome – A Case Study 洞察光谱的Apert综合征-个案研究
Pub Date : 2010-12-31 DOI: 10.5580/c87
R. Narang, S. Sandhu, Sarfaraz Padda, J. Sandhu, A. Manchanda
Apert’s syndrome (Acrocephalo-syndactyly) is a rare congenital, autosomal dominant condition characterized by primary craniosynostosis, mid face malformations and symmetrical syndactyly of the hand and feet. Untreated craniosynostosis leads to inhibition of brain growth and an increase in intracranial and intraorbital pressure. Despite of tremendous advances which have been made in the prevention and treatment of developmental anomalies, they still remain a significant cause of morbidity worldwide. As such, it is incumbent on clinicians to learn as much as possible about this condition so as to improve their ability to handle and prevent them. We present a case of Apert’s syndrome seen in a 10 year old boy. Because of the multiple alterations in patients with Apert syndrome, a multidisciplinary approach, including dentists and neurosurgeons, plastic surgeons, ophthalmologists and geneticists, is essential for a successful planning and treatment. The differences between Apert and Crouzon’s syndrome are also highlighted.
Apert综合征(肩头并指畸形)是一种罕见的先天性常染色体显性遗传病,其特征是原发性颅缝闭合,面部中部畸形和手脚对称并指。未经治疗的颅缝闭锁导致脑生长抑制和颅内压和眶内压增加。尽管在预防和治疗发育异常方面取得了巨大进展,但它们仍然是世界范围内发病率的一个重要原因。因此,临床医生有责任尽可能多地了解这种情况,以提高他们处理和预防这种情况的能力。我们报告一个10岁男孩患阿伯特综合症的病例。由于Apert综合征患者的多种改变,包括牙医、神经外科医生、整形外科医生、眼科医生和遗传学家在内的多学科方法对于成功的计划和治疗至关重要。Apert和Crouzon综合症之间的区别也被强调。
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引用次数: 1
Weight Status Misperception And The Health Behaviors Of Obese Adolescents 肥胖青少年体重状况误解与健康行为
Pub Date : 2010-12-31 DOI: 10.5580/20ea
Peter Thunfors, A. Hanlon, B. Collins
Background: Weight underestimation among U.S. adolescents is common, but the ramifications of this misperception are not yet well known. Purpose: To determine the relationship between weight self-perception and participation in health behaviors among obese adolescents. Methods: The sample consisted of 1,210 obese male and female 7 and 11 graders. Participants completed the Personal Wellness Profile – Teen Edition, a general self-report measure of adolescent health functioning, and had their BMI’s measured. Data were analyzed using Χ tests and logistic regression models. Results: Underestimated weight status was associated with higher reported rates of participation in health behaviors (physical activity, healthy diet, weight management, overall healthy lifestyle) as well as greater self-efficacy in one’s ability to engage in these behaviors. Self-efficacy either partially or fully mediated the relationship between weight underestimation and the health behaviors. Discussion: Both weight perception and self-efficacy should be considered when attempting to understand and predict which adolescents with obesity are likely to engage in health behaviors. For some adolescents it is possible that intervention efforts that emphasize fostering self-efficacy in regard to weight loss behaviors may be more effective than focusing on increasing selfawareness of obese status and the associated risks.
背景:体重低估在美国青少年中很常见,但这种误解的后果尚不为人所知。目的:探讨肥胖青少年体重自我知觉与健康行为参与的关系。方法:调查对象为1210名肥胖男女7、11年级学生。参与者完成了个人健康概况-青少年版,这是一项衡量青少年健康功能的一般自我报告,并测量了他们的体重指数。数据分析采用Χ检验和逻辑回归模型。结果:被低估的体重状况与较高的健康行为(体育活动、健康饮食、体重管理、整体健康生活方式)参与率以及参与这些行为能力的较高自我效能有关。自我效能感在体重低估与健康行为之间有部分或全部中介作用。讨论:当试图理解和预测哪些肥胖青少年可能从事健康行为时,体重感知和自我效能都应该被考虑在内。对于一些青少年来说,强调在减肥行为方面培养自我效能感的干预措施可能比注重提高对肥胖状况和相关风险的自我意识更有效。
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引用次数: 3
Hypertrophic Cardiomyopathy In A Patient With Craniofacial Syndrom: New Cardiocranial Syndrome? 颅面综合征患者的肥厚性心肌病:新的心颅综合征?
Pub Date : 2010-12-31 DOI: 10.5580/28eb
V. Kalra, Fuad M. Kiblawi
We report a 6 year follow up on a patient with a non contributory family history having constellation of anomalies comprising of HOCM, turrencephaly, foreshortened mid face with retrusion of mid facial segment, low set ears, V pattern left exotropia, nystagmus with no developmental delay. DNA analysis of this patient was negative for Pfieffer, Crouzon or Apert syndrome. Review of literature uncovered no similar case reported. We think that this patient represents a new Cardio cranial dysostosis syndrome.
我们报告了一个6年的随访,患者的非贡献性家族史,有一系列的异常,包括HOCM,翻头,面部中部缩短,面部中部向后缩,低耳,V型左外斜视,眼球震颤,无发育迟缓。该患者的DNA分析为Pfieffer, Crouzon或Apert综合征阴性。文献回顾未见类似病例报道。我们认为这个病人代表了一种新的心脑功能障碍综合征。
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引用次数: 0
The Proportion Of Low Birth Weight Babies Due To Small For Gestational Age (Sga) And Prematurity In Port Harcourt, South-South Nigeria - Changing Trends. 尼日利亚南南哈科特港因小于胎龄(Sga)和早产导致的低出生体重婴儿比例——变化趋势。
Pub Date : 2010-12-31 DOI: 10.5580/9a8
R. Ugwu, A. Eneh
Background: Low birth weight (LBW), defined as a birth weight <2500g is basically due to prematurity or small for gestational age (SGA). These infants remain a significant public health problem in both developing and developed countries due to their significantly higher rates of morbidity and mortality.Aim: This study was undertaken to find out the proportion of LBW due to prematurity and SGA in Port Harcourt, South-South Nigeria.Study design: A retrospective chart analysis of babies admitted into the Special Care Baby Unit (SCBU) between January 2002 and December 2009.Results: There were a total of 7,191 admissions into the SCBU within the period with 1,941 (27%) being LBW. A total of 1,463 (75.4%) were preterm LBW while 478 (24.6%) were SGA. Within the same period, there were a total of 20,209 booked live deliveries in the hospital, of which 2,046 were low birth weight babies [preterm LBW 1314(64.2%); term LBW 732 (30.8%)] giving a LBW incidence of 10.1%. The differences in the mean age and height of mothers who delivered an SGA and preterm infant were not statistically significant (p = 0.3 and 0.5 respectively). When compared to mothers of normal weight babies, mothers of LBW babies were significantly younger (p = 0.01) and shorter (p = 0.0001). Identified predisposing factors in preterms were hypertensive disorders, multiple births, antepartum haemorrhages and preterm prelabour rupture of membranes while for SGA, factors identified were malaria in pregnancy, congenital abnormality, multiple gestation, and hypertensive disorders. Mortality was significantly higher in the low birth weight (p=0.000).Conclusion: There seems to be a changing trend in the cause of LBW in our region with prematurity accounting for the greater proportion as found in developed countries. Interventions to prevent the causes of preterm delivery will go a long way in reducing the incidence of LBW in the South South region.
背景:低出生体重(LBW),定义为出生体重<2500g,主要是由于早产或小于胎龄(SGA)所致。由于这些婴儿的发病率和死亡率高得多,它们在发展中国家和发达国家仍然是一个重大的公共卫生问题。目的:本研究旨在了解尼日利亚南南哈科特港因早产和SGA导致的LBW比例。研究设计:回顾性分析2002年1月至2009年12月间入住特殊护理婴儿病房(SCBU)的婴儿。结果:我院共收治7191例患者,其中LBW患者1941例(27%)。早产儿LBW 1463例(75.4%),SGA 478例(24.6%)。在同一时期,该医院共安排了20,209例活产,其中2,046例为低出生体重婴儿[早产婴儿LBW 1314(64.2%);术语lbw732 (30.8%)], LBW发病率为10.1%。分娩SGA和早产母亲的平均年龄和身高差异无统计学意义(p分别为0.3和0.5)。与正常体重婴儿的母亲相比,低体重婴儿的母亲明显更年轻(p = 0.01),更矮(p = 0.0001)。早产的易感因素包括高血压疾病、多胎、产前出血和早产产膜破裂,而SGA的易感因素包括妊娠期疟疾、先天性异常、多胎妊娠和高血压疾病。低出生体重组死亡率显著高于低出生体重组(p=0.000)。结论:在我们地区,LBW的病因似乎有变化的趋势,早产占比比发达国家大。预防早产原因的干预措施将大大有助于减少南南区域的小婴儿发生率。
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引用次数: 10
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The Internet journal of pediatrics and neonatology
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