首页 > 最新文献

The Internet journal of pediatrics and neonatology最新文献

英文 中文
Study of The Cardiac Function of Children Aged from 6 to 59 Months Suffering from Severe Acute Malnutrition in Yaounde Cameroon 喀麦隆雅温得6 ~ 59个月严重急性营养不良儿童心功能研究
Pub Date : 2020-12-28 DOI: 10.33425/2689-1085.1009
D. Chelo, F. Nguefack, Anicet Ngate, Suzanne Sap Ngo Um, H. M. Awa, Paul Olivier Koki Ndomb
Background: Malnutrition is a real public health problem in developing countries. The prevalence remains high in Cameroonian. Context: This condition is regularly accompanied by organ failure. One of the most frequent and severe situations is cardiac involvement with implications on the management of patients. Describing the echocardiographic abnormalities of the heart function of children aged 6 to 59 months hospitalized for Severe Acute Malnutrition (SAM) in the hospitals of Yaoundé was the goal of this study. Knowledge of changes in heart function during the management of SAM will contribute to ameliorating the prognosis, which will also depend on the cardiac lesions. Methods: It was a cross sectional descriptive study carried out in healthcare structures in the town of Yaoundé for a period of 5 months, from January to May 2015. Children aged 6 to 59 months suffering from severe acute malnutrition and hospitalized for at least 6 days were included. We excluded those who had a pathology which could influence heart function. Data collected covered the sociodemographic, clinical and echocardiographic characteristics of the study participants. Results: Most of the 78 children recruited were less than 18 months old (81.08%). The sex ratio was 0.6. Marasmus was the most common type of SAM we found (78.38%). Concerning echocardiography, 35.14% of children had a left ventricular shortening fraction (LVSF) and a Left Ventricular Ejection Fraction (LVEF) less than the 3rd percentile. In all the patients, the speed of the E and A waves was less than -2SD of reference means. The ratio of the E/A waves was less than the 5thpercentile in 35.14%. All had a Tricuspid Annular Plane Systolic Excursion (TAPSE) <-2SD of the reference mean. The decrease of the LVEF was significantly linked to the young age of the patients and to the degree of severity of the malnutrition. Conclusion: severe acute malnutrition is associated with both systolic and diastolic heart failure. Functions of the two ventricles are altered. The severity of heart lesion depends on the degree of malnutrition.
背景:营养不良是发展中国家一个真正的公共卫生问题。喀麦隆的流行率仍然很高。背景:这种情况通常伴有器官衰竭。最常见和最严重的情况之一是心脏受累,对患者的管理有影响。本研究的目的是描述6 ~ 59个月在雅温顿医院因严重急性营养不良(SAM)住院的儿童心功能的超声心动图异常。在SAM治疗过程中了解心功能的变化将有助于改善预后,这也取决于心脏病变。方法:采用横断面描述性研究方法,于2015年1 - 5月在雅温顿镇卫生机构进行为期5个月的调查。患有严重急性营养不良且住院至少6天的6至59个月的儿童也包括在内。我们排除了那些有可能影响心脏功能的病理的人。收集的数据涵盖了研究参与者的社会人口学、临床和超声心动图特征。结果:78例入组儿童中,18月龄以下儿童占81.08%;性别比为0.6。消瘦是我们发现的最常见的SAM类型(78.38%)。超声心动图方面,35.14%的患儿左室缩短分数(LVSF)和左室射血分数(LVEF)均小于第3百分位。所有患者的E波和A波速度均小于参考平均值的-2SD。E/A波小于第5百分位的占35.14%。所有患者均有三尖瓣环平面收缩偏移(TAPSE) <参考平均值的-2SD。LVEF的下降与患者的年龄和营养不良的严重程度显著相关。结论:严重急性营养不良与收缩期和舒张期心力衰竭均相关。两个心室的功能发生改变。心脏病变的严重程度取决于营养不良的程度。
{"title":"Study of The Cardiac Function of Children Aged from 6 to 59 Months Suffering from Severe Acute Malnutrition in Yaounde Cameroon","authors":"D. Chelo, F. Nguefack, Anicet Ngate, Suzanne Sap Ngo Um, H. M. Awa, Paul Olivier Koki Ndomb","doi":"10.33425/2689-1085.1009","DOIUrl":"https://doi.org/10.33425/2689-1085.1009","url":null,"abstract":"Background: Malnutrition is a real public health problem in developing countries. The prevalence remains high in Cameroonian. Context: This condition is regularly accompanied by organ failure. One of the most frequent and severe situations is cardiac involvement with implications on the management of patients. Describing the echocardiographic abnormalities of the heart function of children aged 6 to 59 months hospitalized for Severe Acute Malnutrition (SAM) in the hospitals of Yaoundé was the goal of this study. Knowledge of changes in heart function during the management of SAM will contribute to ameliorating the prognosis, which will also depend on the cardiac lesions. Methods: It was a cross sectional descriptive study carried out in healthcare structures in the town of Yaoundé for a period of 5 months, from January to May 2015. Children aged 6 to 59 months suffering from severe acute malnutrition and hospitalized for at least 6 days were included. We excluded those who had a pathology which could influence heart function. Data collected covered the sociodemographic, clinical and echocardiographic characteristics of the study participants. Results: Most of the 78 children recruited were less than 18 months old (81.08%). The sex ratio was 0.6. Marasmus was the most common type of SAM we found (78.38%). Concerning echocardiography, 35.14% of children had a left ventricular shortening fraction (LVSF) and a Left Ventricular Ejection Fraction (LVEF) less than the 3rd percentile. In all the patients, the speed of the E and A waves was less than -2SD of reference means. The ratio of the E/A waves was less than the 5thpercentile in 35.14%. All had a Tricuspid Annular Plane Systolic Excursion (TAPSE) <-2SD of the reference mean. The decrease of the LVEF was significantly linked to the young age of the patients and to the degree of severity of the malnutrition. Conclusion: severe acute malnutrition is associated with both systolic and diastolic heart failure. Functions of the two ventricles are altered. The severity of heart lesion depends on the degree of malnutrition.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79269572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duplicate Tail Like Right Lower Limb: A Rare Congenital Malformation 双尾状右下肢:一种罕见的先天性畸形
Pub Date : 2020-12-28 DOI: 10.33425/2689-1085.1015
K. Salameh, Rajai Al Bedaywi, N. Elkabir, R. Valappil, Anvar P. Vellamgot, L. Habboub
Introduction: Polymelia (supernumerary limbs) or congenital duplication of limb is an extremely rare condition in humans, with only few cases reported in the literature. Case Report: This is a case of newborn female born with a tail-like extra right leg, which unfortunately was not detected during the routine antenatal ultrasonography. Conclusion: Early diagnosis can facilitate the management planning and psychological preparation of the parents. Surgical resection of the accessory limb at an early age is recommended in patients with polymelia. *Correspondence: Khalil Salameh, Department of Pediatrics and Neonatology, Al Wakra Hospital, Hamad Medical Corporation, Al Wakra, Qatar, Tel: +974 40114258. Received: 04 November 2020; Accepted: 25 November 2020 Journal of Pediatrics & Neonatology ISSN 2689-1085
简介:多肢症(多肢)或先天性肢体重复是一种极为罕见的人类疾病,文献报道的病例很少。病例报告:这是一例新生女性,出生时右腿多出尾巴状,不幸的是在常规产前超声检查中未被发现。结论:早期诊断有助于家长制定治疗计划,做好心理准备。对于多尿症患者,建议在早期手术切除副肢。*通信:Khalil Salameh, Al Wakra医院儿科和新生儿科,哈马德医疗公司,Al Wakra,卡塔尔,电话:+974 40114258。收稿日期:2020年11月4日;收稿日期:2020年11月25日儿科与新生儿杂志ISSN 2689-1085
{"title":"Duplicate Tail Like Right Lower Limb: A Rare Congenital Malformation","authors":"K. Salameh, Rajai Al Bedaywi, N. Elkabir, R. Valappil, Anvar P. Vellamgot, L. Habboub","doi":"10.33425/2689-1085.1015","DOIUrl":"https://doi.org/10.33425/2689-1085.1015","url":null,"abstract":"Introduction: Polymelia (supernumerary limbs) or congenital duplication of limb is an extremely rare condition in humans, with only few cases reported in the literature. Case Report: This is a case of newborn female born with a tail-like extra right leg, which unfortunately was not detected during the routine antenatal ultrasonography. Conclusion: Early diagnosis can facilitate the management planning and psychological preparation of the parents. Surgical resection of the accessory limb at an early age is recommended in patients with polymelia. *Correspondence: Khalil Salameh, Department of Pediatrics and Neonatology, Al Wakra Hospital, Hamad Medical Corporation, Al Wakra, Qatar, Tel: +974 40114258. Received: 04 November 2020; Accepted: 25 November 2020 Journal of Pediatrics & Neonatology ISSN 2689-1085","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76530957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antibiotic Management for Acute Appendicitis in Children: Is it Worth it? 儿童急性阑尾炎的抗生素治疗:值得吗?
Pub Date : 2020-12-28 DOI: 10.33425/2689-1085.1010
L. Gaol, M. Mantu
Introduction: Surgical management of appendicitis in children can reduce its mortality rate, but the risk of complications is comparable. The most common risks in post-operative appendectomy are surgical wound infections, intra-abdominal abscess, and prolonged ileus. The inflammation of the appendix will not always end in perforation because it may resolve spontaneously. This is the result of using antibiotics to reduce the inflammation. The discovery accounts for the decreased appendectomy surgeries. These are the basis for us to conduct research on the use of antibiotics rather than surgery, in appendicitis. Objective: To determine the effect of antibiotic treatments in pediatric appendicitis to prevent surgery. Methods: A prospective cohort method was used with a non-random consecutive sampling of 54 children from January 2015 to January 2016. The diagnosis of appendicitis is made based on clinical symptoms and laboratory results with abdominal tenderness, fever, nausea, vomiting, increased leukocyte and neutrophil count, and an abdominal ultrasound. We obtained 40 children (74.1%) diagnosed with non-complicated appendicitis and treated with two classes of antibiotics and one analgesic. 14 children (25.9%) had complicated appendicitis and received three classes of antibiotics with one analgesic. Each group was observed for 3-5 days of treatment. Results: The group of children with non-complicated appendicitis who resolved only with conservative treatment was 29 children (72.5%) with p value < 0.001. The group of children with complicated appendicitis who resolved with conservative treatment was only 1 child (7.1%) with p value<0.001. There was a significant reduction in pain for both groups (p value<0.001). Conclusion: The use of antibiotics as a type of treatment for non-complicated appendicitis has significant effect to reduce surgery. Its administration also significantly decreased pain in both complicated and non-complicated appendicitis. Further studies with larger sample size are needed to investigate the relationship between antibiotic treatments in pediatric appendicitis to prevent invasive interventions.
儿童阑尾炎的手术治疗可以降低其死亡率,但并发症的风险是相当的。阑尾切除术后最常见的风险是手术伤口感染、腹内脓肿和长时间肠梗阻。阑尾的炎症并不总是以穿孔结束,因为它可能会自行消退。这是使用抗生素消炎的结果。这一发现解释了阑尾切除手术减少的原因。这些是我们研究阑尾炎使用抗生素而不是手术的基础。目的:探讨抗生素治疗小儿阑尾炎预防手术的效果。方法:采用前瞻性队列法,于2015年1月至2016年1月对54名儿童进行非随机连续抽样。阑尾炎的诊断是根据临床症状和实验室结果,腹部压痛,发烧,恶心,呕吐,白细胞和中性粒细胞计数增加,腹部超声检查。我们收集了40例(74.1%)诊断为非并发症阑尾炎的儿童,并使用两类抗生素和一种止痛药进行治疗。合并阑尾炎14例(25.9%),采用3类抗生素加1种镇痛药。每组观察治疗3 ~ 5 d。结果:单纯保守治疗的无并发症阑尾炎患儿29例(72.5%),p值< 0.001。顽固性阑尾炎患儿经保守治疗痊愈的仅有1例(7.1%),p值<0.001。两组患者的疼痛均显著减轻(p值<0.001)。结论:抗生素作为一种治疗非并发症阑尾炎的方法,可显著减少手术次数。它的使用也显著减轻了复杂和非复杂阑尾炎的疼痛。小儿阑尾炎中抗生素治疗与预防侵入性干预的关系需要进一步的大样本量研究。
{"title":"Antibiotic Management for Acute Appendicitis in Children: Is it Worth it?","authors":"L. Gaol, M. Mantu","doi":"10.33425/2689-1085.1010","DOIUrl":"https://doi.org/10.33425/2689-1085.1010","url":null,"abstract":"Introduction: Surgical management of appendicitis in children can reduce its mortality rate, but the risk of complications is comparable. The most common risks in post-operative appendectomy are surgical wound infections, intra-abdominal abscess, and prolonged ileus. The inflammation of the appendix will not always end in perforation because it may resolve spontaneously. This is the result of using antibiotics to reduce the inflammation. The discovery accounts for the decreased appendectomy surgeries. These are the basis for us to conduct research on the use of antibiotics rather than surgery, in appendicitis. Objective: To determine the effect of antibiotic treatments in pediatric appendicitis to prevent surgery. Methods: A prospective cohort method was used with a non-random consecutive sampling of 54 children from January 2015 to January 2016. The diagnosis of appendicitis is made based on clinical symptoms and laboratory results with abdominal tenderness, fever, nausea, vomiting, increased leukocyte and neutrophil count, and an abdominal ultrasound. We obtained 40 children (74.1%) diagnosed with non-complicated appendicitis and treated with two classes of antibiotics and one analgesic. 14 children (25.9%) had complicated appendicitis and received three classes of antibiotics with one analgesic. Each group was observed for 3-5 days of treatment. Results: The group of children with non-complicated appendicitis who resolved only with conservative treatment was 29 children (72.5%) with p value < 0.001. The group of children with complicated appendicitis who resolved with conservative treatment was only 1 child (7.1%) with p value<0.001. There was a significant reduction in pain for both groups (p value<0.001). Conclusion: The use of antibiotics as a type of treatment for non-complicated appendicitis has significant effect to reduce surgery. Its administration also significantly decreased pain in both complicated and non-complicated appendicitis. Further studies with larger sample size are needed to investigate the relationship between antibiotic treatments in pediatric appendicitis to prevent invasive interventions.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90343464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Factors Associated with Sepsis among Neonates Admitted in Kenyatta National Hospital Pediatric Wards 与肯雅塔国家医院儿科病房收治的新生儿脓毒症相关的产妇因素
Pub Date : 2020-12-28 DOI: 10.33425/2689-1085.1014
F. Muthwii, M. Chege, Margret Muiva, Michael Habtu
Introduction: Neonatal sepsis is a major cause of neonatal mortality. The proportion of under-five deaths in the newborn period was found to have increased from 41 per cent (in year 2000) to 46 percent [1]. Statistics indicate that 98% of the global one million deaths as a result of neonatal sepsis occur in Africa. Neonatal sepsis contributes to 28% of neonatal mortality in Kenya. Study objective: The study sought to identify maternal characteristics of mothers to neonates admitted for management of neonatal sepsis in Kenyatta National Hospital (K.N.H) pediatric wards. Methodology: This was a mixed-method study where both quantitative cross-sectional and qualitative approaches were used within K.N.H pediatric wards. A total of 107 study participants were enrolled in the study. The study subjects were selected by systematic random sampling method in which every alternate participant was selected Data was obtained from consenting mothers and healthcare workers. The researcher gathered data on maternal factors associated with the development of neonatal sepsis. Three focused group discussions comprising nurses, doctors and clinical officers were conducted. Data was collected by use of researcher administered semi-structured questionnaire. Qualitative data was audiotaped, transcribed and analyzed into themes. Data was cleaned, entered into computer and analyzed using Statistical Package for Social Sciences (SPSS) version 20. Level of significance was at < 0.05. Study results: Among the sampled mothers, (44.9%) were aged between 20-25 years, (78.5%) were married while fifty-two (48.6%) had attained secondary school education. Fifty-two (47.7%) of the mothers were unemployed and most (42.1%) were earning between KShs of 10,000 – 20,000 per month. More than half 60(56.1%) of the mothers were primiparas. Conclusion The study revealed maternal factors such as primary level of education, low economic class, being a first-time mother and unemployment were common among mothers to newborns admitted with sepsis. *Correspondence: Florence Muthwii, University of Nairobi, College of Health Sciences, School of Nursing Sciences, Nairobi, Kenya. Received: 02 November 2020; Accepted: 17 November 2020 Journal of Pediatrics & Neonatology ISSN 2689-1085
新生儿败血症是新生儿死亡的主要原因。5岁以下儿童在新生儿时期死亡的比例从41%(2000年)增加到46%[1]。统计数据表明,全球因新生儿败血症死亡的100万人中,98%发生在非洲。在肯尼亚,新生儿败血症占新生儿死亡率的28%。研究目的:该研究旨在确定肯雅塔国家医院(K.N.H)儿科病房收治的新生儿脓毒症的母亲的母亲特征。方法学:这是一项混合方法研究,在k.n.h.儿科病房中使用了定量横断面和定性方法。共有107名研究参与者参加了这项研究。研究对象采用系统随机抽样的方法选择,每个候补参与者都被选择。数据来自同意的母亲和医护人员。研究人员收集了与新生儿败血症发展相关的母体因素的数据。进行了三次由护士、医生和临床主任组成的专题小组讨论。数据收集采用研究者管理的半结构化问卷。对定性数据进行录音、转录并分析成主题。对数据进行清理,输入计算机,使用SPSS (Statistical Package for Social Sciences)第20版进行分析。显著性水平< 0.05。研究结果:在抽样的母亲中,年龄在20-25岁之间的占44.9%,已婚的占78.5%,受过中学教育的占52人(48.6%)。52名(47.7%)母亲失业,大多数(42.1%)每月收入在1万至2万肯尼亚先令之间。超过一半(56.1%)的母亲为初产妇。结论产妇因素如教育程度低、经济水平低、首次生育和失业是新生儿脓毒症的常见因素。*通信:Florence Muthwii,内罗毕大学保健科学学院,护理科学学院,肯尼亚内罗毕。收稿日期:2020年11月02日;收稿日期:2020年11月17日儿科与新生儿杂志ISSN 2689-1085
{"title":"Maternal Factors Associated with Sepsis among Neonates Admitted in Kenyatta National Hospital Pediatric Wards","authors":"F. Muthwii, M. Chege, Margret Muiva, Michael Habtu","doi":"10.33425/2689-1085.1014","DOIUrl":"https://doi.org/10.33425/2689-1085.1014","url":null,"abstract":"Introduction: Neonatal sepsis is a major cause of neonatal mortality. The proportion of under-five deaths in the newborn period was found to have increased from 41 per cent (in year 2000) to 46 percent [1]. Statistics indicate that 98% of the global one million deaths as a result of neonatal sepsis occur in Africa. Neonatal sepsis contributes to 28% of neonatal mortality in Kenya. Study objective: The study sought to identify maternal characteristics of mothers to neonates admitted for management of neonatal sepsis in Kenyatta National Hospital (K.N.H) pediatric wards. Methodology: This was a mixed-method study where both quantitative cross-sectional and qualitative approaches were used within K.N.H pediatric wards. A total of 107 study participants were enrolled in the study. The study subjects were selected by systematic random sampling method in which every alternate participant was selected Data was obtained from consenting mothers and healthcare workers. The researcher gathered data on maternal factors associated with the development of neonatal sepsis. Three focused group discussions comprising nurses, doctors and clinical officers were conducted. Data was collected by use of researcher administered semi-structured questionnaire. Qualitative data was audiotaped, transcribed and analyzed into themes. Data was cleaned, entered into computer and analyzed using Statistical Package for Social Sciences (SPSS) version 20. Level of significance was at < 0.05. Study results: Among the sampled mothers, (44.9%) were aged between 20-25 years, (78.5%) were married while fifty-two (48.6%) had attained secondary school education. Fifty-two (47.7%) of the mothers were unemployed and most (42.1%) were earning between KShs of 10,000 – 20,000 per month. More than half 60(56.1%) of the mothers were primiparas. Conclusion The study revealed maternal factors such as primary level of education, low economic class, being a first-time mother and unemployment were common among mothers to newborns admitted with sepsis. *Correspondence: Florence Muthwii, University of Nairobi, College of Health Sciences, School of Nursing Sciences, Nairobi, Kenya. Received: 02 November 2020; Accepted: 17 November 2020 Journal of Pediatrics & Neonatology ISSN 2689-1085","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83540069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Multi-Detector Computed Tomography Classify (MDCT) Non-Compacted Left Ventricle in Coloration to The Genetic Structure? 多检测器计算机断层扫描(MDCT)是否可以根据遗传结构对非压缩左心室进行分类?
Pub Date : 2019-09-24 DOI: 10.33425/2689-1085.1004
M. Nabo
Introduction Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity [1]. The clinical sequelae of these deformities are the syndrome of heart failure, arrhythmias and stroke. Dusek first described the postnatal persistence of spongy myocardium in 1975 pathologically, but Engberding and Bender made the first clinical recognition with two-dimensional (2D) echocardiography in 1984 [2,3]. Three decades later, with only morphologic assessment available and no definitive genetic pathway, isolated left ventricular noncompaction (LVNC) remains a diagnostic and management challenge. In this review, we wish to spot light on how MDCT can visualize the shape and distribution of spongy myocardium clearer than echocardiography.
孤立性左室不压实(LVNC)是一种遗传性心肌病,其特征是突出的心室小梁和与左室腔相通的深小梁间窝或窦状窝[1]。这些畸形的临床后遗症是心力衰竭、心律失常和中风的综合征。Dusek于1975年首次在病理学上描述了海绵状心肌在出生后的持续存在,Engberding和Bender于1984年通过二维超声心动图首次在临床中发现[2,3]。三十年后,由于只有形态学评估,没有明确的遗传途径,孤立性左室非压实(LVNC)仍然是诊断和治疗的挑战。在这篇综述中,我们希望阐明MDCT如何比超声心动图更清晰地显示海绵状心肌的形状和分布。
{"title":"Can Multi-Detector Computed Tomography Classify (MDCT) Non-Compacted Left Ventricle in Coloration to The Genetic Structure?","authors":"M. Nabo","doi":"10.33425/2689-1085.1004","DOIUrl":"https://doi.org/10.33425/2689-1085.1004","url":null,"abstract":"Introduction Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity [1]. The clinical sequelae of these deformities are the syndrome of heart failure, arrhythmias and stroke. Dusek first described the postnatal persistence of spongy myocardium in 1975 pathologically, but Engberding and Bender made the first clinical recognition with two-dimensional (2D) echocardiography in 1984 [2,3]. Three decades later, with only morphologic assessment available and no definitive genetic pathway, isolated left ventricular noncompaction (LVNC) remains a diagnostic and management challenge. In this review, we wish to spot light on how MDCT can visualize the shape and distribution of spongy myocardium clearer than echocardiography.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90093402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Factors Associated with Pulmonary Arterial Hypertension (PAH) in Sickle Cell Children Residing in Yaoundé, Cameroon 喀麦隆雅温德省镰状细胞儿童肺动脉高压(PAH)患病率及相关因素
Pub Date : 2019-06-30 DOI: 10.33425/2689-1085.1005
C. David, F. Kessel, B. Hamadou, Mbom Ghislain, Kamdem Sandrine, A. Yanda, Shu Beckly, Y. Nathan
Introduction: Sickle cell disease is the most widespread single gene disease in the world. Pulmonary arterial hypertension (PAH), a late complication, is one of its most serious causes of morbidity and mortality. In the absence of data on PAH in paediatric settings in Cameroon, we proposed to conduct a prevalence study and research on its determinants in a group of sickle cell patients. General Objective: Identify the determinants of pulmonary arterial hypertension in a group of children with major sickle cell disease. Methods: We conducted a cross-sectional and analytical study from November 1, 2017 to May 31, 2018 in a group of sickle cell children regularly monitored at the Mother and Child Centre of the Chantal Biya Foundation. For each patient recruited, we collected socio-demographic data, medical history, clinical, biological and echocardiographic data. PAH was defined as mean pulmonary arterial pressure (mPAP)>25mmHg, obtained by measuring the pressure gradient between the pulmonary artery and the right ventricle (Bernoulli equation), to which we added the pressure of the right atrium. The data were analyzed with IBM SPSS 21.0. The association between variables was assessed by the Chi-square or Fisher test for qualitative variables and the Student t-test or Pearson Rho correlation test for quantitative variables. Results: Overall, we enrolled 129 patients, 79 (61.2%) were female. That is to say a sex ratio Male/Female of 0.63. The average age was 11.6 ± 3.2 years. We found PAH (mPAP>25mmHg) in 27 (20.9%) patients. In univariate analysis, the determinants found were high age (p=0.001), presence of dyspnea (p<0.001), high number of blood transfusions (p=0.043), history of pneumonia (p=0.01) dilated LV (DLV) (p=0.031) and dilated aorta (DA) (p=0.05). In multivariate analysis, the independent determinants we found were: age (p=0.041); high number of blood transfusions (p=0.005); history of pneumonia (p<0.001) and dyspnea (p=0.001). Conclusion: PAH is a common complication of sickle cell disease in children and its independent determinants are: age, number of blood transfusions, history of pneumonia, and dyspnea.
镰状细胞病是世界上最广泛的单基因疾病。肺动脉高压(PAH)是一种晚期并发症,是其最严重的发病和死亡原因之一。在缺乏喀麦隆儿科多环芳烃数据的情况下,我们建议在一组镰状细胞患者中开展一项患病率研究和其决定因素研究。总体目的:确定一组患有严重镰状细胞病的儿童肺动脉高压的决定因素。方法:我们于2017年11月1日至2018年5月31日在Chantal Biya基金会母婴中心定期监测的一组镰状细胞儿童中进行了横断面和分析研究。对于每个招募的患者,我们收集了社会人口统计数据、病史、临床、生物学和超声心动图数据。PAH定义为平均肺动脉压(mPAP)>25mmHg,通过测量肺动脉和右心室之间的压力梯度(伯努利方程)得到,我们在其中加入了右心房的压力。采用IBM SPSS 21.0软件对数据进行分析。对于定性变量,采用卡方检验或Fisher检验;对于定量变量,采用学生t检验或Pearson Rho相关检验。结果:我们共纳入129例患者,其中79例(61.2%)为女性。也就是说,男女性别比为0.63。平均年龄11.6±3.2岁。我们在27例(20.9%)患者中发现PAH (mPAP>25mmHg)。单因素分析发现,年龄大(p=0.001)、存在呼吸困难(p<0.001)、输血次数多(p=0.043)、肺炎史(p=0.01)、左室扩张(p=0.031)和主动脉扩张(p=0.05)是决定因素。在多变量分析中,我们发现的独立决定因素是:年龄(p=0.041);输血次数高(p=0.005);肺炎史(p<0.001)和呼吸困难史(p=0.001)。结论:PAH是儿童镰状细胞病的常见并发症,其独立决定因素为:年龄、输血次数、肺炎史和呼吸困难。
{"title":"Prevalence and Factors Associated with Pulmonary Arterial Hypertension (PAH) in Sickle Cell Children Residing in Yaoundé, Cameroon","authors":"C. David, F. Kessel, B. Hamadou, Mbom Ghislain, Kamdem Sandrine, A. Yanda, Shu Beckly, Y. Nathan","doi":"10.33425/2689-1085.1005","DOIUrl":"https://doi.org/10.33425/2689-1085.1005","url":null,"abstract":"Introduction: Sickle cell disease is the most widespread single gene disease in the world. Pulmonary arterial hypertension (PAH), a late complication, is one of its most serious causes of morbidity and mortality. In the absence of data on PAH in paediatric settings in Cameroon, we proposed to conduct a prevalence study and research on its determinants in a group of sickle cell patients. General Objective: Identify the determinants of pulmonary arterial hypertension in a group of children with major sickle cell disease. Methods: We conducted a cross-sectional and analytical study from November 1, 2017 to May 31, 2018 in a group of sickle cell children regularly monitored at the Mother and Child Centre of the Chantal Biya Foundation. For each patient recruited, we collected socio-demographic data, medical history, clinical, biological and echocardiographic data. PAH was defined as mean pulmonary arterial pressure (mPAP)>25mmHg, obtained by measuring the pressure gradient between the pulmonary artery and the right ventricle (Bernoulli equation), to which we added the pressure of the right atrium. The data were analyzed with IBM SPSS 21.0. The association between variables was assessed by the Chi-square or Fisher test for qualitative variables and the Student t-test or Pearson Rho correlation test for quantitative variables. Results: Overall, we enrolled 129 patients, 79 (61.2%) were female. That is to say a sex ratio Male/Female of 0.63. The average age was 11.6 ± 3.2 years. We found PAH (mPAP>25mmHg) in 27 (20.9%) patients. In univariate analysis, the determinants found were high age (p=0.001), presence of dyspnea (p<0.001), high number of blood transfusions (p=0.043), history of pneumonia (p=0.01) dilated LV (DLV) (p=0.031) and dilated aorta (DA) (p=0.05). In multivariate analysis, the independent determinants we found were: age (p=0.041); high number of blood transfusions (p=0.005); history of pneumonia (p<0.001) and dyspnea (p=0.001). Conclusion: PAH is a common complication of sickle cell disease in children and its independent determinants are: age, number of blood transfusions, history of pneumonia, and dyspnea.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77869635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and Practices of Physicians in Managing Pediatric Community Acquired Pneumonia (CAP) in a Major city in United Arab Emirates (UAE) 阿拉伯联合酋长国(UAE)某主要城市医生管理儿科社区获得性肺炎(CAP)的知识与实践
Pub Date : 2019-06-30 DOI: 10.33425/2689-1085.1001
Aisha Almaazmi, Muna A Al Dhaibani, Hossam Al Tatari
Objectives: The study aims to assess the knowledge, attitude and practices of physicians who deal with pediatric CAP in reference to the Infectious Diseases Society of America (IDSA) guidelines on this regard that was published in 2011. Background: Community acquired pneumonia (CAP) is a common disease and the leading cause of death among children worldwide. However, there seems to be large diversity among physicians when it comes to diagnosis, investigation and treatment of the condition, despite a recent clinical practice guideline that was released in August 2011 by the Pediatric Infectious Diseases Society of America (IDSA guideline). Method: An anonymous 15-item survey exploring knowledge, attitude and practices related to diagnosis and management of Pediatric CAP was distributed to physicians of different levels of experience (from residents to consultants) in the departments of Pediatrics, Emergency Medicine and Family Medicine in different governmental and private facilities in Al-Ain city.
目的:本研究旨在参照2011年出版的美国传染病学会(IDSA)关于这方面的指南,评估处理儿科CAP的医生的知识、态度和做法。背景:社区获得性肺炎(CAP)是一种常见病,也是全世界儿童死亡的主要原因。然而,尽管美国儿科传染病学会(IDSA)于2011年8月发布了最新的临床实践指南,但在诊断、调查和治疗方面,医生之间似乎存在很大的差异。方法:对Al-Ain市不同公立和私立医院儿科、急诊医学和家庭医学的不同经验水平的医生(从住院医生到会诊医生)进行15项匿名调查,探讨与儿科CAP诊断和管理相关的知识、态度和做法。
{"title":"Knowledge and Practices of Physicians in Managing Pediatric Community Acquired Pneumonia (CAP) in a Major city in United Arab Emirates (UAE)","authors":"Aisha Almaazmi, Muna A Al Dhaibani, Hossam Al Tatari","doi":"10.33425/2689-1085.1001","DOIUrl":"https://doi.org/10.33425/2689-1085.1001","url":null,"abstract":"Objectives: The study aims to assess the knowledge, attitude and practices of physicians who deal with pediatric CAP in reference to the Infectious Diseases Society of America (IDSA) guidelines on this regard that was published in 2011. Background: Community acquired pneumonia (CAP) is a common disease and the leading cause of death among children worldwide. However, there seems to be large diversity among physicians when it comes to diagnosis, investigation and treatment of the condition, despite a recent clinical practice guideline that was released in August 2011 by the Pediatric Infectious Diseases Society of America (IDSA guideline). Method: An anonymous 15-item survey exploring knowledge, attitude and practices related to diagnosis and management of Pediatric CAP was distributed to physicians of different levels of experience (from residents to consultants) in the departments of Pediatrics, Emergency Medicine and Family Medicine in different governmental and private facilities in Al-Ain city.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83668335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Episodes of Retrograde Jejunogastric and Jejunojejunal Intussusceptions as a Complication of Gastrostomy Tube in a Child: A Case Report 2例儿童胃造口管并发空肠-胃逆行肠套叠1例
Pub Date : 2019-01-01 DOI: 10.33425/2689-1085.1003
Sakulsansern Kwanhathai, Tunruttanakul Suppadech, Ruangwattanapaisarn Nichanan, Sritippho Nopporn
Gastrostomy tubes are frequently used to provide enteral access in some pediatric patients. Serious long-term complications are rare. The case-report here is a 12 years-old neurologically impaired child who had gastrostomy done for pharyngeal incoordination, presented eight years later with intestinal obstruction and upper gastrointestinal bleeding. Various imaging modalities were utilized and showed a retrograde jejuno-gastric intussusception around the gastrostomy tube. Six days after laparotomy and manual reduction, a perforated recurrent jejuno-jejunal intussusception occurred. Series of subsequent interventions were followed. This report aims to raise awareness of this uncommon but potential lethal complication concurrently with a discussion on diagnosis and management. We also provided a set of associated and useful imaging which is the important diagnostic tool.
在一些儿科患者中,胃造口管经常用于提供肠内通路。严重的长期并发症很少见。这里的病例报告是一个12岁的神经功能受损的孩子,他做了胃造口术治疗咽不协调,8年后出现肠梗阻和上消化道出血。利用各种成像方式显示胃造口管周围有逆行的空肠-胃肠套叠。开腹后6天,手工复位,穿孔复发空肠肠套叠发生。随后进行了一系列干预。本报告旨在提高对这种罕见但潜在致命并发症的认识,同时讨论诊断和管理。我们还提供了一套相关的和有用的影像,这是重要的诊断工具。
{"title":"Two Episodes of Retrograde Jejunogastric and Jejunojejunal Intussusceptions as a Complication of Gastrostomy Tube in a Child: A Case Report","authors":"Sakulsansern Kwanhathai, Tunruttanakul Suppadech, Ruangwattanapaisarn Nichanan, Sritippho Nopporn","doi":"10.33425/2689-1085.1003","DOIUrl":"https://doi.org/10.33425/2689-1085.1003","url":null,"abstract":"Gastrostomy tubes are frequently used to provide enteral access in some pediatric patients. Serious long-term complications are rare. The case-report here is a 12 years-old neurologically impaired child who had gastrostomy done for pharyngeal incoordination, presented eight years later with intestinal obstruction and upper gastrointestinal bleeding. Various imaging modalities were utilized and showed a retrograde jejuno-gastric intussusception around the gastrostomy tube. Six days after laparotomy and manual reduction, a perforated recurrent jejuno-jejunal intussusception occurred. Series of subsequent interventions were followed. This report aims to raise awareness of this uncommon but potential lethal complication concurrently with a discussion on diagnosis and management. We also provided a set of associated and useful imaging which is the important diagnostic tool.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77795720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Birth to Discharge: Neonatal Simulation Clinical Experiences 出生到出院:新生儿模拟临床经验
Pub Date : 2018-07-23 DOI: 10.33140/ijwhc/03/02/00008
C. DeGraw
With an increase in nursing programs to combat the projected nursing shortage, there is more competition for clinical sitesfor Obstetric-Neonatal clinical rotations. Obstetric and neonatal simulation clinical experiences are being substituted forhospital clinical rotations and for lack of patients during clinical rotations. A technical college in Southeastern UnitedStates is using five-hour simulation clinical experiences, in which Obstetric and Neonatal high-fidelity manikins are utilized,as substitutes for hospital clinical rotations or lack of Obstetric-Neonatal patients. Neonatal nursing care is related tothe type of disorder the pregnant patient is admitted with to the Antepartum/ Intrapartum Simulation Laboratory HospitalUnit. Three patient scenarios are used for the clinical experiences: neonates born to mothers with gestational diabetes,preeclampsia, or preterm labor. Neonatal complications such as hypoglycemia and prematurity are incorporated into thescenarios. Nursing students use fetal monitoring to identify fetal complications to provide appropriate nursing care to theneonate after delivery. This use of simulation clinical experiences has been endorsed by the National Council of State Boardsof Nursing and the National League of Nursing as a substitute for hospital clinical rotations. The significance of usingObstetric-Neonatal simulation clinical experiences is increased understanding by nursing students of the entire antepartumthrough postpartum nursing care and discharge process. Using the high-fidelity manakins and fetal monitoring, nursingstudents can obtain hands-on experience when unable to obtain the clinical experience due to lack of a hospital rotationsite or lack of patients during their hospital clinical rotation.
随着护理项目的增加,以应对预计的护理短缺,产科-新生儿临床轮转的临床场地竞争更加激烈。产科和新生儿模拟临床经验正在取代医院临床轮转和临床轮转期间病人不足的情况。美国东南部的一所技术学院正在使用5小时的模拟临床经验,其中使用了产科和新生儿高保真模型,作为医院临床轮转或缺乏产科新生儿患者的替代品。新生儿护理与孕妇在产前/产时模拟实验室住院的疾病类型有关。临床经验使用了三种患者情况:患有妊娠糖尿病的母亲所生的新生儿,先兆子痫或早产。新生儿并发症,如低血糖症和早产被纳入情景。护理专业学生使用胎儿监护来识别胎儿并发症,以便在分娩后为新生儿提供适当的护理。这种模拟临床经验的使用已经得到了国家护理委员会和国家护理联盟的认可,作为医院临床轮转的替代品。运用产科-新生儿模拟临床经验的意义在于通过产后护理和出院过程增加护生对整个产前的了解。使用高保真manakins和胎儿监护,护理学生可以在缺乏医院轮岗或医院轮岗期间缺乏患者而无法获得临床经验时获得实践经验。
{"title":"Birth to Discharge: Neonatal Simulation Clinical Experiences","authors":"C. DeGraw","doi":"10.33140/ijwhc/03/02/00008","DOIUrl":"https://doi.org/10.33140/ijwhc/03/02/00008","url":null,"abstract":"With an increase in nursing programs to combat the projected nursing shortage, there is more competition for clinical sites\u0000for Obstetric-Neonatal clinical rotations. Obstetric and neonatal simulation clinical experiences are being substituted for\u0000hospital clinical rotations and for lack of patients during clinical rotations. A technical college in Southeastern United\u0000States is using five-hour simulation clinical experiences, in which Obstetric and Neonatal high-fidelity manikins are utilized,\u0000as substitutes for hospital clinical rotations or lack of Obstetric-Neonatal patients. Neonatal nursing care is related to\u0000the type of disorder the pregnant patient is admitted with to the Antepartum/ Intrapartum Simulation Laboratory Hospital\u0000Unit. Three patient scenarios are used for the clinical experiences: neonates born to mothers with gestational diabetes,\u0000preeclampsia, or preterm labor. Neonatal complications such as hypoglycemia and prematurity are incorporated into the\u0000scenarios. Nursing students use fetal monitoring to identify fetal complications to provide appropriate nursing care to the\u0000neonate after delivery. This use of simulation clinical experiences has been endorsed by the National Council of State Boards\u0000of Nursing and the National League of Nursing as a substitute for hospital clinical rotations. The significance of using\u0000Obstetric-Neonatal simulation clinical experiences is increased understanding by nursing students of the entire antepartum\u0000through postpartum nursing care and discharge process. Using the high-fidelity manakins and fetal monitoring, nursing\u0000students can obtain hands-on experience when unable to obtain the clinical experience due to lack of a hospital rotation\u0000site or lack of patients during their hospital clinical rotation.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73602025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoglycemia And Supraventricular Tachycardia In An Infant Of Diabetic Mother: A Possible Association. 糖尿病母亲的婴儿低血糖和室上性心动过速:可能的联系。
Pub Date : 2013-01-03 DOI: 10.5580/2ce5
Vijayakumar Praveen, Hasanain Adnan, S. Praveen, J. Schuster, Luis A. Ayo
3 to 10 % of all pregnancies are associated with some degree of glucose dysregulation. 90% of those are related to gestational diabetes. Infant born to diabetic mothers with poor glycemic control, have greater associated morbidity and mortality. Hypoglycemia is the common manifestation in such infants, with an incidence of up to 50 % in the immediate postnatal period 2, Atrioventricular block has been documented in infants of diabetic mother (IDM). 4 Reactive hypoglycemia has been reported to trigger atrioventricular nodal reentry tachycardia in an adult. We describe a macrosomic IDM, who developed severe hypoglycemia and simultaneous supraventricular tachycardia (SVT) in the immediate postnatal period, suggesting a possible association and biological plausibility. Sinus rhythm was established with adenosine and after institution of stable euglycemia.
3%到10%的怀孕与某种程度的葡萄糖失调有关。其中90%与妊娠糖尿病有关。糖尿病母亲生下的婴儿血糖控制不良,有更高的相关发病率和死亡率。低血糖是这类婴儿的常见表现,在出生后立即发生的发生率高达50% 2,在糖尿病母亲(IDM)的婴儿中有文献记载。有报道称,一例成人反应性低血糖可引发房室结性再入性心动过速。我们描述了一个巨大的IDM,谁发展严重的低血糖和同时室上性心动过速(SVT)在出生后的直接时期,提示可能的关联和生物学合理性。窦性心律是在腺苷和稳定血糖后建立的。
{"title":"Hypoglycemia And Supraventricular Tachycardia In An Infant Of Diabetic Mother: A Possible Association.","authors":"Vijayakumar Praveen, Hasanain Adnan, S. Praveen, J. Schuster, Luis A. Ayo","doi":"10.5580/2ce5","DOIUrl":"https://doi.org/10.5580/2ce5","url":null,"abstract":"3 to 10 % of all pregnancies are associated with some degree of glucose dysregulation. 90% of those are related to gestational diabetes. Infant born to diabetic mothers with poor glycemic control, have greater associated morbidity and mortality. Hypoglycemia is the common manifestation in such infants, with an incidence of up to 50 % in the immediate postnatal period 2, Atrioventricular block has been documented in infants of diabetic mother (IDM). 4 Reactive hypoglycemia has been reported to trigger atrioventricular nodal reentry tachycardia in an adult. We describe a macrosomic IDM, who developed severe hypoglycemia and simultaneous supraventricular tachycardia (SVT) in the immediate postnatal period, suggesting a possible association and biological plausibility. Sinus rhythm was established with adenosine and after institution of stable euglycemia.","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70822091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Internet journal of pediatrics and neonatology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1