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Profile of Patients with Maxillofacial Fracture in Emergency Department, Head-Neck Surgery Division, Dr. Soetomo Public Hospital Surabaya in 2020 2020年泗水Soetomo医生公立医院头颈外科急诊科颌面部骨折患者概况
Pub Date : 2022-12-01 DOI: 10.22452/adum.vol28no12
Reynard Budy Setiawan, Marjono Dwi Wibowo
Maxillofacial fracture is the most common form of injury in trauma patients, especially in patients with motor vehicle accidents. The COVID-19 pandemic has affected various sectors, including restrictions on people's mobility. This study aims to determine the profile of patients with maxillofacial fractures during the COVID-19 pandemic. A descriptive observational study was conducted to evaluate maxillofacial fracture patients who came to the Emergency Department of the Head-Neck Surgery Division of the Dr. Soetomo Surabaya Hospital in 2020. Subjects were grouped according to sex, age, month of visit and the mechanism of trauma. The ratio between men and women was 4.92:1. The largest age distribution is in the 11-20 years range, as much as 39.2%. The most distribution based on the month of visit was in February as much as 16.9%. Most trauma mechanisms were due to traffic accidents (90.1%). Most locations in single maxillofacial fractures in maxillary bone were 37.8% and multiple maxillofacial fractures in zygoma bones were 79.4%. Accompanying trauma was found in 73.2% of subjects, with the highest pattern of intracranial trauma as much as 80.8%. The incidence of single maxillofacial fractures was 47.9% and multiple maxillofacial fractures were 52.1%, with concomitant trauma occurring in 73.2% of subjects.
颌面部骨折是创伤患者最常见的损伤形式,尤其是机动车事故患者。新冠肺炎疫情影响了各个部门,包括对人员流动的限制。本研究旨在确定新冠肺炎大流行期间颌面部骨折患者的概况。进行了一项描述性观察性研究,以评估2020年来泗水Soetomo医生医院头颈外科急诊科的颌面部骨折患者。受试者根据性别、年龄、就诊月份和创伤机制进行分组。男女比例为4.92:1。年龄分布最大的是11~20岁,高达39.2%。按就诊月份分布最多的是2月份,高达16.9%。大多数创伤机制是由交通事故引起的(90.1%)。上颌骨单个颌面部骨折的大多数部位为37.8%,颧骨多发颌面部骨折为79.4%。73.2%的受试者发现伴随创伤,其中颅内创伤的发生率最高,高达80.8%。单颌面部骨折的发生率为47.9%,多颌面部骨折发生率为52.1%,伴发创伤的受试者占73.2%。
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引用次数: 0
Detection of Genetic Alterations in Oral Squamous Cell Carcinoma Using Multiplex Ligation-Dependent Probe Amplification (MLPA) 多重结扎依赖探针扩增(MLPA)检测口腔鳞状细胞癌基因改变
Pub Date : 2022-09-12 DOI: 10.22452/adum.vol29no6
Zachary Wei Ern Yong, L. P. Karen-Ng, T. G. Kallarakkal, Z. A. Abdul Rahman, S. Ismail, M. T. Abraham, K. Tay, R. Zain, Z. Mohamad Zaini
Deletions and amplifications of genes often occur during multistep progression from oral precancer, seen as oral epithelial dysplasia (OED) to cancerous stage. These genetic alterations could be used as markers to aid in detection of oral squamous cell carcinomas (OSCC). This study explored the use of multiplex ligation-dependent probe amplification (MLPA) technique in detecting OSCC and OED specific genetic alterations. MLPA was used to detect gains and losses of 106 genes in DNA extracted from frozen tissue samples of 10 OSCC and 10 non-cancer patients. Two biopsies of OED were analyzed to explore the alterations in oral potentially malignant disorders. There were significant differences (p<0.001) in the number of alterations in OSCC and dysplasia compared to non-cancer samples respectively. The most frequently altered genes in OSCC were PTP4A3, RECQL4, ATM, and KLK3 (60%). Five genes (MYC, SLA, TNFRSF1A, MESDC1, MIF) were altered in 50% of OSCC samples. These nine genes were specific to OSCC samples (p<0.05). Some genes, including MYB, MET, CASP2, SLA and PTEN occurred in 50% of OED samples. MLPA was able to detect genetic alterations, that are present only in OSCC samples and showed potential to be used as an adjunctive tool in early diagnosis of OSCC.
基因的缺失和扩增通常发生在从口腔癌前病变(口腔上皮发育不良(OED))到癌期的多步骤进展过程中。这些基因改变可以作为标记物来帮助检测口腔鳞状细胞癌(OSCC)。本研究探讨了多重连接依赖性探针扩增(MLPA)技术在检测OSCC和OED特异性遗传改变中的应用。MLPA用于检测从10例OSCC和10例非癌患者的冷冻组织样本中提取的DNA中106个基因的获得和丢失。对两例OED活检进行分析,以探讨口腔潜在恶性疾病的改变。与非癌样本相比,OSCC和发育不良的改变数量分别存在显著差异(p<0.001)。OSCC中最常改变的基因是PTP4A3、RECQL4、ATM和KLK3(60%)。五个基因(MYC、SLA、TNFRSF1A、MESDC1、MIF)在50%的OSCC样本中发生了改变。这9个基因在OSCC样本中具有特异性(p<0.05)。一些基因,包括MYB、MET、CASP2、SLA和PTEN,在50%的OED样本中出现。MLPA能够检测仅存在于OSCC样本中的基因改变,并显示出作为OSCC早期诊断辅助工具的潜力。
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引用次数: 0
COVID-19 Impact on Dental Clinical Education: An Observational Narrative COVID-19对牙科临床教育的影响:一项观察性叙述
Pub Date : 2022-07-13 DOI: 10.22452/adum.vol29no5
Noorhayati Raja Mohd, Aly Abdelrehim, Nosizana Mohd Salleh
As a means to combat the coronavirus disease (COVID-19) global pandemic, educational institutes were forced to stop the accustomed face-to-face teaching methods and adopt an online scheme to ensure the continuity of the education process. Furthermore, only a minimal period of clinical training was offered to the students during the pandemic and this highlighted the critical need to expand and improve the dental simulation curriculum. This article aims to highlight the impact of COVID-19 pandemic on the students and educators in dental schools. This perspective paper will also discuss the effectiveness of online teaching and the challenges in learning environment at the Faculty of Dentistry, Universiti Malaya during the pandemic, based on observations and published literature.
作为抗击冠状病毒疾病(新冠肺炎)全球大流行的一种手段,教育机构被迫停止习惯的面对面教学方法,采用在线计划,以确保教育过程的连续性。此外,在疫情期间,只为学生提供了最短时间的临床培训,这突出了扩大和改进牙科模拟课程的迫切需要。本文旨在强调新冠肺炎大流行对牙科学校学生和教育工作者的影响。这篇前瞻性论文还将根据观察和发表的文献,讨论疫情期间马来亚大学牙科学院在线教学的有效性和学习环境中的挑战。
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引用次数: 1
Misconceptions, Hesitancy and Efficacy of COVID-19 Vaccination in Dental Surgeons Working in A Teaching Dental Hospital, Peshawar 白沙瓦一家教学牙科医院牙科外科医生对COVID-19疫苗接种的误解、犹豫和效果
Pub Date : 2022-06-08 DOI: 10.22452/adum.vol29no4
Aalia Zaib, Syed Imran Gilani, Asif Muhammad, Ubaid Zaib
The objective of this study was to assess misconceptions, hesitancy and efficacy of COVID-19 Vaccine among Faculty, House Officers (HO) and Postgraduates (PG) dental trainees towards the novel COVID-19 vaccine and to assess the association between COVID-19 vaccine acceptance and conspiracy beliefs. A cross sectional study was conducted on 150 participants from Sardar Begum Dental hospital, Peshawar, Khyber Pakhtunkhwa. A self-administered questionnaire was developed with questions related to perception of participants regarding misconceptions, safety, hesitancy and efficacy of COVID-19 Vaccination. The questionnaire comprised of 26 closed-ended questions. Data was analyzed using SPSS statistical package 26.0. More than half of the participants (87.3%) reported to be tested positive for COVID-19 at some point. Majority of participants (87.3%) reported that they were vaccinated and 86.7% reported that they had post-vaccination reactions such as pain in arm, fever and body aches. A notable number of participants that were part of the study believed in the misconceptions related to the COVID-19 vaccine. This study concluded that despite widespread vaccination awareness campaigns, significant number of dental surgeons believed in misconceptions regarding COVID-19 vaccination that may pose a significant challenge to Pakistan's COVID-19 immunization program.
本研究的目的是评估教员、内务官员(HO)和研究生(PG)牙科受训人员对新型新冠肺炎疫苗的误解、犹豫和疗效,并评估新冠肺炎疫苗接受与阴谋信念之间的关联。对来自开伯尔-普赫图赫瓦白沙瓦萨达尔贝古姆牙科医院的150名参与者进行了横断面研究。制定了一份自填问卷,其中涉及参与者对新冠肺炎疫苗接种的误解、安全性、犹豫和有效性的看法。问卷由26个封闭式问题组成。数据采用SPSS统计软件包26.0进行分析。超过一半的参与者(87.3%)报告在某个时候新冠肺炎检测呈阳性。大多数参与者(87.3%)报告说他们接种了疫苗,86.7%的人报告说他们有接种后的反应,如手臂疼痛、发烧和身体疼痛。参与该研究的大量参与者相信与新冠肺炎疫苗相关的误解。这项研究得出的结论是,尽管开展了广泛的疫苗接种宣传活动,但大量牙科医生认为对新冠肺炎疫苗接种存在误解,这可能会对巴基斯坦的新冠肺炎免疫计划构成重大挑战。
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引用次数: 0
Presence of the Periodontal Bacterium Porphyromonas gingivalis in Patients With and Without Cancer: A Meta-analysis 有无癌症患者牙周细菌牙龈卟啉单胞菌的存在:一项荟萃分析
Pub Date : 2022-04-20 DOI: 10.22452/adum.vol29no3
A. Rodríguez-Archilla, Eugenia Encina-Palazzolo
A high presence of periodontal pathogens such as Porphyromonas gingivalis (P. gingivalis) has been found in cancers at different body locations. The imbalance of the oral microbiome (dysbiosis) promotes the chronic inflammatory process that could contribute to carcinogenesis. To assess the P. gingivalis detection in cancer patients. A search for studies on P. gingivalis and neoplasms was conducted from 1974 to 2021 in the following databases: PubMed (MEDLINE), Cochrane Library, Web of Science (WoS), and Scopus. For dichotomous outcomes, the estimates of effects of an intervention were expressed as odds ratios (OR) using Mantel-Haenszel (M-H) method with 95% confidence intervals. Funnel plot and Egger’s test for publication bias analysis were used. Also, Newcastle-Ottawa (NOS) studies methodological quality assessment scale was employed. Thirteen studies that involved 1732 cancer patients and 3298 controls without cancer were included in this meta-analysis. P. gingivalis detection was 1.81 times more likely in cancer patients (p<0.01) compared to controls. P. gingivalis detection was also more likely in patients with colorectal (OR: 2.00, p=0.02) or pancreatic (OR: 1.32, p=0.02) tumors. In contrast, oral, esophageal, lung, or breast cancers did not show a significant increase of P. gingivalis detection (p>0.05).
牙龈卟啉单胞菌(P. gingivalis)等牙周病原体在不同身体部位的癌症中都有很高的存在。口腔微生物群的不平衡(生态失调)促进了慢性炎症过程,可能导致致癌。目的:评价肿瘤患者牙龈假单胞菌的检出率。从1974年到2021年,我们在PubMed (MEDLINE)、Cochrane图书馆、Web of Science (WoS)和Scopus数据库中检索了牙龈卟啉卟啉菌和肿瘤的研究。对于二分类结果,干预效果的估计使用Mantel-Haenszel (M-H)方法表示为优势比(OR),置信区间为95%。采用漏斗图和Egger’s检验进行发表偏倚分析。采用纽卡斯尔-渥太华(NOS)研究方法学质量评定量表。这项荟萃分析纳入了13项研究,涉及1732名癌症患者和3298名非癌症对照。肿瘤患者牙龈假单胞菌检出率是肿瘤患者的1.81倍(p0.05)。
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引用次数: 0
Successful Reconstructive Surgery for Facial Deformity Caused by Paederus fuscipes: An Illustrative Case Report 面部畸形的成功重建手术:一个说明性病例报告
Pub Date : 2022-04-14 DOI: 10.22452/adum.vol29no2
Rusni Noordin, Anis Marlina Ibne Walid, Muhammad Ridwan Yeop Ismail, Shah Kamal Khan Jamal Din
Full thickness skin graft is a simple and reliable method for closure of small facial wound defect. A thorough understanding of how a skin graft heals and how to perform the procedure is essential for successful outcome. We report the use of full thickness skin graft in a wound closure of a facial skin defect caused by Paederus fuscipes, locally known as charlie. An 8-year old boy developed blister and painful swelling over his right cheek following skin contact with charlie. This lesion gradually became extensive, eventually leading to tissue loss and facial wound defect. A full thickness skin grafting was performed with satisfactory functional and excellent aesthetic result.
全厚皮片是一种简单可靠的面部小面积创面修复方法。彻底了解皮肤移植如何愈合以及如何进行手术对于成功的结果至关重要。我们报告了全厚皮片移植在面部皮肤缺损的伤口闭合中的应用,该缺损由隐翅虫引起,当地称为charlie。一名8岁男孩在与查理皮肤接触后,右脸颊出现水泡和疼痛肿胀。这种病变逐渐扩大,最终导致组织损失和面部伤口缺损。进行了全厚植皮,取得了令人满意的功能和良好的美观效果。
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引用次数: 0
Factors Affecting Sorption and Solubility of Denture Base Acrylic Materials: A Review 影响义齿基托丙烯酸材料吸附和溶解度的因素综述
Pub Date : 2022-02-23 DOI: 10.22452/adum.vol29no1
Rian George Barnard, Peter C. Clarke-Farr, A. Latief
Heat-cured PMMA is one of the most frequently used materials in the manufacture of removable dentures. Heat-cured material used to fabricate dentures contain soluble elements, allowing the material to absorb and release substances. These factors all directly affect the longevity and performance of protheses fabricated from polymethyl methacrylate denture base material. Various procedures associated with fabrication of removable dentures from heat-cure denture base material are reported to significantly influence the sorption and solubility experienced by the prosthesis. A comprehensive search of peer-reviewed journals located within academic databases was conducted to identify relevant literature pertaining to sorption and solubility of denture base materials. Key aspects of each paper were captured in Microsoft® Excel® to record author/s, location, study design, sample size, methodology, results and conclusions. Mixing ratios and polymerisation cycles have been identified as variables that can negatively influence the rate of sorption and solubility of denture base materials during the fabrication process. Certain surface treatment procedures, as well as storing the denture in artificial saliva solution may reduce the levels of sorption and solubility experienced and optimise its lifespan. In this review we identify these factors and consider the detrimental effects of sorption and solubility on denture base acrylic materials.
热固化PMMA是制造活动义齿中最常用的材料之一。用于制造假牙的热固化材料含有可溶性元素,使材料能够吸收和释放物质。这些因素都直接影响到聚甲基丙烯酸甲酯义齿基托材料的使用寿命和使用性能。据报道,用热固化义齿基托材料制作活动义齿的各种过程会显著影响义齿的吸附和溶解度。对学术数据库中的同行评审期刊进行了全面的搜索,以确定与义齿基托材料的吸附和溶解度有关的相关文献。在Microsoft®Excel®中记录每篇论文的关键方面,记录作者、地点、研究设计、样本量、方法、结果和结论。在制造过程中,混合比例和聚合周期已被确定为可能对义齿基托材料的吸附速率和溶解度产生负面影响的变量。某些表面处理程序,以及将义齿储存在人工唾液溶液中,可能会降低义齿的吸收水平和溶解度,并优化其使用寿命。在本文中,我们识别了这些因素,并考虑了吸附和溶解度对义齿基托丙烯酸材料的有害影响。
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引用次数: 1
Revisiting the Microleakage in Tooth-coloured Sandwich Restorations 牙齿彩色夹层修复术中微渗漏的再认识
Pub Date : 2021-12-16 DOI: 10.22452/adum.vol28no11
Jian Sheng Lee, N. A. Yahya, M. Gonzalez
The placement of glass ionomer cement as lining material below composite fillings was introduced by McLean and Wilson in 1977. This technique incorporated different layers of restorative materials placed onto tooth, similar to layers of a sandwich. It was proposed this technique will provide a molecular seal to dentine in addition to mechanical and aesthetic properties of composite resin. Placement of liner or an intermediate layer underneath the main bulk of restorative materials reduces polymerization shrinkage stress and resultant microleakage of the final restoration. To date, dentine adhesion and polymerization shrinkage are limitations of resin-based restorative materials. At present, wide array of tooth-coloured restorative materials with different formulations is available. Despite advancements in restorative dentistry, no single technique or material is ideal in both clinical effectiveness and simplicity. Clinicians may find themselves in a dilemma when choosing restorative materials and techniques that provide the best clinical results with minimal technique sensitivity or chairside time. The aim of this review is to present existing scientific evidence in microleakage and sandwich technique in restorations, and to discuss multiple approaches in sandwich restorations in effort to reduce microleakage of dental restorations. Clinical recommendations will be given based on evidence from multiple studies.
1977年,McLean和Wilson介绍了在复合填料下方放置玻璃离聚物水泥作为衬里材料。这种技术将不同的修复材料层放在牙齿上,类似于三明治层。有人提出,除了复合树脂的机械和美学性能外,这项技术还将为牙本质提供分子密封。在主要的修复材料下面放置衬垫或中间层可以减少聚合收缩应力和最终修复的微渗漏。到目前为止,牙本质粘附和聚合收缩是树脂基修复材料的局限性。目前,有多种不同配方的牙齿彩色修复材料可供选择。尽管修复性牙科取得了进步,但没有一种单一的技术或材料在临床有效性和简单性方面都是理想的。临床医生在选择修复材料和技术时可能会发现自己陷入了困境,这些材料和技术能够以最小的技术敏感性或主持时间提供最佳的临床结果。本综述的目的是介绍修复体中微渗漏和夹层技术的现有科学证据,并讨论夹层修复体的多种方法,以减少牙齿修复体的微渗漏。将根据多项研究的证据提出临床建议。
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引用次数: 0
Transverse Facial Cleft, Tessier number 7: Case Report of a Rare Congenital Anomaly 面部横裂,Tessier 7号:一例罕见的先天性畸形
Pub Date : 2021-11-24 DOI: 10.22452/adum.vol28no10
B. Ezenwa, I. Fajolu, Pauline Kasarachi Akowundu, Khadijah Oleolo-Ayodeji, O. James, V. Ezeaka
Transverse facial cleft (TFC), Tessier number 7, is a rare congenital anomaly commonly associated with other anomalies of the first and second branchial arch with varying severity. Risk factors such as alcohol abuse, folic acid deficiency, and ingestion of herbal concoctions in pregnancy have been implicated in this deformity. We report a case of a bilateral transverse facial cleft in a newborn and review the existing literature on the condition to increase awareness and knowledge.
横切面裂(TFC), Tessier 7号,是一种罕见的先天性异常,通常与第一和第二鳃弓的其他异常有关,其严重程度不同。危险因素,如酗酒,叶酸缺乏,和摄入草药混合物在怀孕期间牵连到这种畸形。我们报告一例新生儿双侧横切面裂,并回顾现有文献,以提高认识和知识。
{"title":"Transverse Facial Cleft, Tessier number 7: Case Report of a Rare Congenital Anomaly","authors":"B. Ezenwa, I. Fajolu, Pauline Kasarachi Akowundu, Khadijah Oleolo-Ayodeji, O. James, V. Ezeaka","doi":"10.22452/adum.vol28no10","DOIUrl":"https://doi.org/10.22452/adum.vol28no10","url":null,"abstract":"Transverse facial cleft (TFC), Tessier number 7, is a rare congenital anomaly commonly associated with other anomalies of the first and second branchial arch with varying severity. Risk factors such as alcohol abuse, folic acid deficiency, and ingestion of herbal concoctions in pregnancy have been implicated in this deformity. We report a case of a bilateral transverse facial cleft in a newborn and review the existing literature on the condition to increase awareness and knowledge.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41547066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Dietary Challenges on the Flexural Properties of Resin-based Composites 日粮挑战对树脂基复合材料抗弯性能的影响
Pub Date : 2021-07-31 DOI: 10.22452/ADUM.VOL28NO9
N. A. Yahya, Shin Ye Lim, M. Gonzalez
This study aims to compare flexural strength and flexural modulus of different resin-based composites (RBCs) and to determine the impact of dietary solvents on flexural properties. Forty specimens (12x2x2mm) for each of two conventional (Aura Easy [AE]; Harmonize [HN]) and one bulk fill (Sonic Fill 2 [SF2]) were fabricated using customised plastic moulds. Specimens were light-cured, measured and randomly divided into four groups. The groups (n=10) were conditioned for 7 days at 37°C: in one of media: air (control), artificial saliva (SAGF), 0.02N citric acid and 50% ethanol–water solution. After conditioning, the specimens subjected to flexural testing. Two-way ANOVA and one-way ANOVA (post hoc: Tukey’s or Dunnett T3 tests) were used at a=0.05. Significant differences in flexural properties were observed between materials and conditioning media. Flexural strength and modulus values ranged from 124.85MPa to 51.25MPa; and 6.76GPa to 4.03GPa, respectively. The highest flexural properties were obtained with conditioning in air. Exposure to aqueous solutions generally reduced flexural properties. In conclusion, the effect of dietary solvents on flexural properties were material and medium dependent. For functional longevity of restorations, patients’ alcohol intake should be considered during material selection. Dietary advice (reduce alcohol consumption) should be given to patients post operatively.
本研究旨在比较不同树脂基复合材料(rbc)的抗弯强度和抗弯模量,并确定膳食溶剂对抗弯性能的影响。两种常规(Aura Easy [AE];Harmonize [HN])和一个散装填充(Sonic fill 2 [SF2])是使用定制的塑料模具制造的。标本经光固化、测量后随机分为四组。各组(n=10)分别在空气(对照)、人工唾液(SAGF)、0.02N柠檬酸和50%乙醇-水溶液中进行37℃条件下培养7 d。调理后,试件进行抗弯试验。采用双因素方差分析和单因素方差分析(事后:Tukey’s或Dunnett T3检验),a=0.05。在材料和调节介质之间观察到弯曲性能的显着差异。抗折强度和模量为124.85 ~ 51.25MPa;和6.76 - 4.03GPa。在空气中调节获得最高的弯曲性能。暴露在水溶液中通常会降低弯曲性能。综上所述,日粮溶剂对弯曲性能的影响与材料和介质有关。为了延长修复体的功能寿命,在材料选择时应考虑患者的酒精摄入量。术后患者应给予饮食建议(减少饮酒)。
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引用次数: 0
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Annals of dentistry
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