The presence of lobulated tumour arising from immature adipose tissue is called lipoblastoma when occurring as localised or discrete lesion, and lipoblastomatosis when spread diffusely. The purpose of this case study is to report a case of an 18 – year old man who presented with lipoblastoma in the left sublingual space which was found to be in close proximity with the left sublingual gland. Magnetic resonance imaging (MRI) was taken and showed the tumour was confined within the sublingual space and no penetration was noted inferiorly through the mylohyoid muscle. Tumour dimension measured clinically was 3 cm x 2 cm x 2 cm and the anterior margin of the tumour crossed the midline and entered into the right sublingual space. Complete excision with sparing of neurovascular bundle was performed under general anaesthesia. Follow-up of 2 months showed complete remission of the lesion without any complications.
由未成熟脂肪组织引起的分叶肿瘤，当作为局部或离散病变发生时称为脂肪母细胞瘤，当扩散时称为成脂细胞瘤。本病例研究的目的是报告一名18岁男性的病例，他在左舌下间隙出现脂肪母细胞瘤，发现该间隙与左舌下腺非常接近。进行了磁共振成像（MRI），显示肿瘤被限制在舌下空间内，没有发现通过下颌舌骨肌的下方穿透。临床测量的肿瘤尺寸为3cm x 2cm x 2cm，肿瘤前缘越过中线进入右舌下间隙。在全身麻醉下进行完全切除并保留神经血管束。随访2个月，病变完全缓解，无任何并发症。
{"title":"The Challenges of Treating Lipoblastoma in the Sublingual Space – A Case Report","authors":"Sujesh Sreedharan, P. Shanmuhasuntharam","doi":"10.22452/ADUM.VOL28NO8","DOIUrl":"https://doi.org/10.22452/ADUM.VOL28NO8","url":null,"abstract":"The presence of lobulated tumour arising from immature adipose tissue is called lipoblastoma when occurring as localised or discrete lesion, and lipoblastomatosis when spread diffusely. The purpose of this case study is to report a case of an 18 – year old man who presented with lipoblastoma in the left sublingual space which was found to be in close proximity with the left sublingual gland. Magnetic resonance imaging (MRI) was taken and showed the tumour was confined within the sublingual space and no penetration was noted inferiorly through the mylohyoid muscle. Tumour dimension measured clinically was 3 cm x 2 cm x 2 cm and the anterior margin of the tumour crossed the midline and entered into the right sublingual space. Complete excision with sparing of neurovascular bundle was performed under general anaesthesia. Follow-up of 2 months showed complete remission of the lesion without any complications.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46152626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agustin Wulan Suci-Dharmayanti, Ajeng Nurwahyuningtyas Anjani, A. Handayani, Z. Hamzah, Z. Meilawaty, Masniari Novita, Mei Syafriadi, A. D. Shita
The ovaries represent the female reproductive organs that determine the women's fertility status and their systemic and oral health, correlating to sex steroid hormone alteration. This study aimed to investigate the effect of cassava leaves extract treatment to SOD expression in the animal model-ovaries after Porphyromonas gingivalis injection. 15 female Sprague Dawley rats were used and divided into five groups: (1) control without cassava leaves extract treatment (C); (2) P. gingivalis without cassava leaves extract treatment (T1); (3) P. gingivalis and cassava leaves extract (T2); (4) P. gingivalis and vitamin C (T3); and (5) P. gingivalis and metronidazole (T4). Animal were euthanised at day seven after the initial treatment to collect ovaries. The ovaries sections were immunohistochemically stained to quantify SOD expression using light microscope while the Image J software was used to quantify the SOD expression. The results showed that all of the follicle types had the same intensity of SOD expression. Most of the follicles exhibited low intensity of SOD expression, except for atretic follicles. In conclusion, P. gingivalis and cassava leaves extract influenced SOD expression in the ovaries of animal models, which increased the SOD expression.
{"title":"Superoxide Dismutase Expression in the Ovaries of Periodontitis Animal Models Induced by Porphyromonas gingivalis and Treated with Cassava Leaves Extract","authors":"Agustin Wulan Suci-Dharmayanti, Ajeng Nurwahyuningtyas Anjani, A. Handayani, Z. Hamzah, Z. Meilawaty, Masniari Novita, Mei Syafriadi, A. D. Shita","doi":"10.22452/ADUM.VOL28NO7","DOIUrl":"https://doi.org/10.22452/ADUM.VOL28NO7","url":null,"abstract":"The ovaries represent the female reproductive organs that determine the women's fertility status and their systemic and oral health, correlating to sex steroid hormone alteration. This study aimed to investigate the effect of cassava leaves extract treatment to SOD expression in the animal model-ovaries after Porphyromonas gingivalis injection. 15 female Sprague Dawley rats were used and divided into five groups: (1) control without cassava leaves extract treatment (C); (2) P. gingivalis without cassava leaves extract treatment (T1); (3) P. gingivalis and cassava leaves extract (T2); (4) P. gingivalis and vitamin C (T3); and (5) P. gingivalis and metronidazole (T4). Animal were euthanised at day seven after the initial treatment to collect ovaries. The ovaries sections were immunohistochemically stained to quantify SOD expression using light microscope while the Image J software was used to quantify the SOD expression. The results showed that all of the follicle types had the same intensity of SOD expression. Most of the follicles exhibited low intensity of SOD expression, except for atretic follicles. In conclusion, P. gingivalis and cassava leaves extract influenced SOD expression in the ovaries of animal models, which increased the SOD expression.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48609290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Aimi Amalina, Sawri Rajan Poornima, Sukumaran Prema, Abdullah Mariam, Mohd Noor Nora Sakina, Khan Asfand Ali
This study is aimed to provide an insight into the types of treatment carried out by postgraduate students in the past 10 years. A retrospective study was carried out between November 2019 and February 2020 by deriving data from postgraduate students’ clinical logbooks of three different cohorts of Master of Clinical Dentistry (Restorative Dentistry in Conservative Dentistry) in 2010, 2013 and 2016. This retrospective data was systematically extracted from the records and tabulated categorically using an Excel spreadsheet (Microsoft Office Excel 2019). A descriptive analysis was carried out to further evaluate the results. Overall, the types of treatment carried out in the field of endodontics and fixed prosthodontics has changed in the past 10 years. An increasing trend is seen in the placement of all ceramic crowns and primary root canal treatment procedures, while a decreasing pattern is evident for secondary root canal procedures and placement of dental bridges.
{"title":"The Trends of Endodontic and Prosthodontic Treatment by Postgraduate Students in University of Malaya","authors":"Ahmad Aimi Amalina, Sawri Rajan Poornima, Sukumaran Prema, Abdullah Mariam, Mohd Noor Nora Sakina, Khan Asfand Ali","doi":"10.22452/adum.vol28no6","DOIUrl":"https://doi.org/10.22452/adum.vol28no6","url":null,"abstract":"This study is aimed to provide an insight into the types of treatment carried out by postgraduate students in the past 10 years. A retrospective study was carried out between November 2019 and February 2020 by deriving data from postgraduate students’ clinical logbooks of three different cohorts of Master of Clinical Dentistry (Restorative Dentistry in Conservative Dentistry) in 2010, 2013 and 2016. This retrospective data was systematically extracted from the records and tabulated categorically using an Excel spreadsheet (Microsoft Office Excel 2019). A descriptive analysis was carried out to further evaluate the results. Overall, the types of treatment carried out in the field of endodontics and fixed prosthodontics has changed in the past 10 years. An increasing trend is seen in the placement of all ceramic crowns and primary root canal treatment procedures, while a decreasing pattern is evident for secondary root canal procedures and placement of dental bridges.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43391948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The amount of incisor decompensation during pre-surgical orthodontics may affect the outcome of Class III orthognathic cases. The purpose of this study was to assess the lower incisor changes post-orthodontic decompensation in Class III surgical cases and to investigate the amount of crowding as a predictive factor. This was a retrospective study reporting on 22 Class III orthognathic cases. The lower incisor angulation (LIA) and distance of the lower incisor edge to the A-Pogonion line (Li-APo) were measured on pre-treatment and pre-surgical lateral cephalograms whereas crowding was measured on digitised pre-treatment study models. Pearson’s correlation (p <0.05) was used to assess the correlation of crowding with LIA and Li-APo changes, and prediction of the lower incisor decompensation was conducted using linear regression analysis. Results showed lower incisors were retroclined at 79.84° ± 7.08° and positioned ahead of APo line by 6.52 mm ± 2.97 mm at the start of treatment. Pre-surgical LIA and Li-APo were found to increase following orthodontic decompensation to 90.43° ± 5.96° and 10.34 mm ± 3.25 mm, respectively. There was a moderate positive correlation (r = 0.592) between crowding and Li-APo changes which was statistically significant, p value = 0.004, and had a strong predictor with 31.8% predictability. However, LIA showed a weak correlation (r = 0.329) with crowding and was not statistically significant (p = 0.135). Li-APo changes during orthodontic decompensation can be predicted with 31.8% predictability using the formula; Li-APo change = 2.064 + 0.503 (crowding).
{"title":"Lower incisor changes following non-extraction orthodontic decompensation in Class III surgical cases","authors":"N. Zakaria, Y. Kamarudin, K. S. Ong, Zi Qing Koo","doi":"10.22452/ADUM.VOL28NO3","DOIUrl":"https://doi.org/10.22452/ADUM.VOL28NO3","url":null,"abstract":"The amount of incisor decompensation during pre-surgical orthodontics may affect the outcome of Class III orthognathic cases. The purpose of this study was to assess the lower incisor changes post-orthodontic decompensation in Class III surgical cases and to investigate the amount of crowding as a predictive factor. This was a retrospective study reporting on 22 Class III orthognathic cases. The lower incisor angulation (LIA) and distance of the lower incisor edge to the A-Pogonion line (Li-APo) were measured on pre-treatment and pre-surgical lateral cephalograms whereas crowding was measured on digitised pre-treatment study models. Pearson’s correlation (p <0.05) was used to assess the correlation of crowding with LIA and Li-APo changes, and prediction of the lower incisor decompensation was conducted using linear regression analysis. Results showed lower incisors were retroclined at 79.84° ± 7.08° and positioned ahead of APo line by 6.52 mm ± 2.97 mm at the start of treatment. Pre-surgical LIA and Li-APo were found to increase following orthodontic decompensation to 90.43° ± 5.96° and 10.34 mm ± 3.25 mm, respectively. There was a moderate positive correlation (r = 0.592) between crowding and Li-APo changes which was statistically significant, p value = 0.004, and had a strong predictor with 31.8% predictability. However, LIA showed a weak correlation (r = 0.329) with crowding and was not statistically significant (p = 0.135). Li-APo changes during orthodontic decompensation can be predicted with 31.8% predictability using the formula; Li-APo change = 2.064 + 0.503 (crowding).","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43277049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. H. Kassim, Abdul Latif Abdul Hamid, Nadhirah Ghazali, Puvanendran Balasingham
Management of traumatic dental injuries (TDI) in a young patient may range from simple to complex. In a situation where teeth are lost, a reliable and conservative treatment option is an implant-supported fixed dental prosthesis (i-FDP), as this treatment option negates the need to prepare sound abutment teeth as in the case of conventional fixed bridges. However, the placement of implants is usually prosthetically driven to allow for a 3D functional and aesthetic restoration. In the presence of severe skeletal Class III malocclusion, treatment may incorporate pre-surgical orthodontic treatment, followed by jaw surgery to correct the skeletal discrepancies and finally post-surgical orthodontic treatment before the rehabilitation with implants. A multidisciplinary treatment approach in a stepwise manner is required to address the patient’s overall treatment needs. This case report presents a joint prosthodontics, orthodontics and oral maxillofacial surgical management of a young adult male patient with a Skeletal Class III malocclusion who required rehabilitation of avulsed missing anterior teeth sustained from childhood TDI. The severity of the skeletal relationship required a Le Fort I maxillary advancement and a bilateral sagittal split osteotomy for the setback of the mandible in combination with orthodontics for correction of malocclusion and arch relationship prior to implant placement. Correction of the malocclusion and jaw deformity allowed the functional and aesthetic rehabilitation of the missing teeth using an i-FDP.
年轻患者创伤性牙损伤(TDI)的处理可能从简单到复杂。在牙齿脱落的情况下，一种可靠而保守的治疗选择是种植体支持的固定义齿(i-FDP)，因为这种治疗选择不需要像传统的固定桥那样准备良好的基牙。然而，植入物的放置通常是假体驱动，以允许3D功能和美学修复。如果存在严重的骨骼III类错牙合，治疗可能包括术前正畸治疗，然后进行颌骨手术纠正骨骼差异，最后进行术后正畸治疗，然后进行种植体康复。一个多学科的治疗方法在一个循序渐进的方式是必需的，以解决患者的整体治疗需要。本病例报告报告了一个年轻的成年男性患者的关节修复，正畸和口腔颌面外科治疗的骨骼III类错，谁需要康复撕脱缺失的前牙持续儿童TDI。由于骨骼关系的严重程度，需要进行Le Fort I上颌前进和双侧矢状劈开截骨术来矫正下颌骨后退，并在种植体植入前进行正畸治疗以纠正错颌和弓关系。使用i-FDP矫正错颌畸形，使缺失牙齿的功能和美观恢复。
{"title":"A Rehabilitation of Missing Maxillary Anterior Teeth in a Severe Skeletal Class III Malocclusion Patient Requiring Implants","authors":"Z. H. Kassim, Abdul Latif Abdul Hamid, Nadhirah Ghazali, Puvanendran Balasingham","doi":"10.22452/ADUM.VOL28NO2","DOIUrl":"https://doi.org/10.22452/ADUM.VOL28NO2","url":null,"abstract":"Management of traumatic dental injuries (TDI) in a young patient may range from simple to complex. In a situation where teeth are lost, a reliable and conservative treatment option is an implant-supported fixed dental prosthesis (i-FDP), as this treatment option negates the need to prepare sound abutment teeth as in the case of conventional fixed bridges. However, the placement of implants is usually prosthetically driven to allow for a 3D functional and aesthetic restoration. In the presence of severe skeletal Class III malocclusion, treatment may incorporate pre-surgical orthodontic treatment, followed by jaw surgery to correct the skeletal discrepancies and finally post-surgical orthodontic treatment before the rehabilitation with implants. A multidisciplinary treatment approach in a stepwise manner is required to address the patient’s overall treatment needs. This case report presents a joint prosthodontics, orthodontics and oral maxillofacial surgical management of a young adult male patient with a Skeletal Class III malocclusion who required rehabilitation of avulsed missing anterior teeth sustained from childhood TDI. The severity of the skeletal relationship required a Le Fort I maxillary advancement and a bilateral sagittal split osteotomy for the setback of the mandible in combination with orthodontics for correction of malocclusion and arch relationship prior to implant placement. Correction of the malocclusion and jaw deformity allowed the functional and aesthetic rehabilitation of the missing teeth using an i-FDP.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48190874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prema Sukumaran, Siti Nurshakina Abdul Kamar, Nur Azwa Nadia M Zalani, D. Nambiar, R. Vaithilingam, K. Goh
Extra esophageal manifestation of Gastro-esophageal reflux disease (GERD) include erosive wear dental lesions. Early erosive wear lesions in this group of patients can be easily missed as they are accompanied by few clinical signs and hardly any symptoms. This case series aims to report the prevalence and severity of erosive wear lesions amongst a sample of GERD patients in Malaysia. Eleven subjects with well characterized GERD, diagnosed based on modified Reflux Disease Questionnaire (RDQ) or via endoscopy, were included in this case series. A standardized intra oral clinical examination was performed to assess presence and severity of erosive wear lesions on tooth surfaces using Basic Erosive Wear Examination (BEWE) index. Majority of BEWE score 1 lesions were distributed in maxillary anterior teeth, followed by maxillary posterior and mandibular teeth. BEWE score 2 lesions were most prevalent in maxillary anterior teeth and there were no BEWE score 3 lesions observed. Based on the clinical findings, more erosive wear lesions were found on the buccal surfaces of maxillary and mandibular teeth in GERD patients. This case series further confirms the link between GERD and erosive wear lesions. The authors would like to highlight the need for both medical and dental practitioners to be aware of early clinical presentations of GERD and erosive wear lesions. Early diagnoses allow for intervention and conservative management of these conditions.
{"title":"Prevalence of erosive wear lesions in Gastro-Esophageal Reflux Disease patients – A case series","authors":"Prema Sukumaran, Siti Nurshakina Abdul Kamar, Nur Azwa Nadia M Zalani, D. Nambiar, R. Vaithilingam, K. Goh","doi":"10.22452/ADUM.VOL28NO1","DOIUrl":"https://doi.org/10.22452/ADUM.VOL28NO1","url":null,"abstract":"Extra esophageal manifestation of Gastro-esophageal reflux disease (GERD) include erosive wear dental lesions. Early erosive wear lesions in this group of patients can be easily missed as they are accompanied by few clinical signs and hardly any symptoms. This case series aims to report the prevalence and severity of erosive wear lesions amongst a sample of GERD patients in Malaysia. Eleven subjects with well characterized GERD, diagnosed based on modified Reflux Disease Questionnaire (RDQ) or via endoscopy, were included in this case series. A standardized intra oral clinical examination was performed to assess presence and severity of erosive wear lesions on tooth surfaces using Basic Erosive Wear Examination (BEWE) index. Majority of BEWE score 1 lesions were distributed in maxillary anterior teeth, followed by maxillary posterior and mandibular teeth. BEWE score 2 lesions were most prevalent in maxillary anterior teeth and there were no BEWE score 3 lesions observed. Based on the clinical findings, more erosive wear lesions were found on the buccal surfaces of maxillary and mandibular teeth in GERD patients. This case series further confirms the link between GERD and erosive wear lesions. The authors would like to highlight the need for both medical and dental practitioners to be aware of early clinical presentations of GERD and erosive wear lesions. Early diagnoses allow for intervention and conservative management of these conditions.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46273588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prabha Kadakampallil John, Thomas George Valliaveettil, A. George, Alenya Mary Pyas
Platelet concentrates are derivatives of blood that aid in haemostasis and wound healing after periodontal regenerative procedures. Its ability to act as a natural scaffold of growth factors has gained significance in many surgical procedures. This review article aims to briefly describe the different platelet concentrates used in the field of periodontology.
{"title":"Platelet concentrates for periodontal regeneration","authors":"Prabha Kadakampallil John, Thomas George Valliaveettil, A. George, Alenya Mary Pyas","doi":"10.22452/adum.vol27no9","DOIUrl":"https://doi.org/10.22452/adum.vol27no9","url":null,"abstract":"Platelet concentrates are derivatives of blood that aid in haemostasis and wound healing after periodontal regenerative procedures. Its ability to act as a natural scaffold of growth factors has gained significance in many surgical procedures. This review article aims to briefly describe the different platelet concentrates used in the field of periodontology.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44237885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Shaban, K. Mokhtar, S. Ichwan, A. Ashour, Basma Ezzat Mustafa Al-Ahmad
General health benefits have been demonstrated by natural products. Flaxseed (Linum usitatissimum) extract’s bioactivities have been reported in many studies such as antimicrobial, anti-oxidant, and anti-inflammatory effects. In addition, flaxseed extract has skin wound healing activity and potential for treating oral ulcers. Methodology: L. usitatissimum was extracted using 70% ethanol via soxhlet method, gas chromatography mass spectrum (GC-MS) was used to illustrate the components of L. usitatissimum extract. Human oral fibroblasts (HOrF) were cultured to be used for testing the activity of L. usitatissimum. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was used to assess the HOrF cells viability at different time point; 24, 48 and 72 hours. Wound healing assay was used to monitor the healing of HOrF cells after treating them with flaxseed extract. The results of the assay were obtained at 18, 24, 48 and 72 hours. Results: The results of GC-MS illustrate the major components present in L. usitatissimum extract. The effect of L. usitatissimum extract on HOrF cells show high proliferation effect at 24 and 48 hours while the highest proliferation effect was recorded at 72 hours’ post-treatment. Wound healing assay results show healing activity of L. usitatissimum extract on HOrF cells as fast as 18 hours’ post-treatment. Conclusion: L. usitatissimum extract have proliferating and healing effects on HOrF cell line. Therefore, it can be considered as a potential promising oral wound healing agent.
{"title":"Flaxseed (Linum usitatissimum) Extract Activity on Human Oral Fibroblasts (HOrF) Cell Line","authors":"S. Shaban, K. Mokhtar, S. Ichwan, A. Ashour, Basma Ezzat Mustafa Al-Ahmad","doi":"10.22452/ADUM.VOL27NO8","DOIUrl":"https://doi.org/10.22452/ADUM.VOL27NO8","url":null,"abstract":"General health benefits have been demonstrated by natural products. Flaxseed (Linum usitatissimum) extract’s bioactivities have been reported in many studies such as antimicrobial, anti-oxidant, and anti-inflammatory effects. In addition, flaxseed extract has skin wound healing activity and potential for treating oral ulcers. Methodology: L. usitatissimum was extracted using 70% ethanol via soxhlet method, gas chromatography mass spectrum (GC-MS) was used to illustrate the components of L. usitatissimum extract. Human oral fibroblasts (HOrF) were cultured to be used for testing the activity of L. usitatissimum. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was used to assess the HOrF cells viability at different time point; 24, 48 and 72 hours. Wound healing assay was used to monitor the healing of HOrF cells after treating them with flaxseed extract. The results of the assay were obtained at 18, 24, 48 and 72 hours. Results: The results of GC-MS illustrate the major components present in L. usitatissimum extract. The effect of L. usitatissimum extract on HOrF cells show high proliferation effect at 24 and 48 hours while the highest proliferation effect was recorded at 72 hours’ post-treatment. Wound healing assay results show healing activity of L. usitatissimum extract on HOrF cells as fast as 18 hours’ post-treatment. Conclusion: L. usitatissimum extract have proliferating and healing effects on HOrF cell line. Therefore, it can be considered as a potential promising oral wound healing agent.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47156253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Khairul Anwar Mohd Tahir, A. Ramanathan, George Boey Teik Foo, S. Gopalan, Marzuki Zainal Abidin, F. Rahman
Pilomatrixoma is an uncommon benign tumour arising from the matrix and inner sheath of a normal hair follicle as well as hair cortex. It is usually presented as a superficial, solitary, firm mass which is asymptomatic and slowly growing. It accounts for about 0.2% of all routine skin specimens and may poses a diagnostic challenge as it may resemble other common benign lesions found in the head and neck region. We report a case of a 33-year old men presented to us with a pilomatrixoma of the right cheek, surgical management and histological findings.
{"title":"Pilomatrixoma of the Cheek – A Case Report","authors":"Mohd Khairul Anwar Mohd Tahir, A. Ramanathan, George Boey Teik Foo, S. Gopalan, Marzuki Zainal Abidin, F. Rahman","doi":"10.22452/adum.vol27no5","DOIUrl":"https://doi.org/10.22452/adum.vol27no5","url":null,"abstract":"Pilomatrixoma is an uncommon benign tumour arising from the matrix and inner sheath of a normal hair follicle as well as hair cortex. It is usually presented as a superficial, solitary, firm mass which is asymptomatic and slowly growing. It accounts for about 0.2% of all routine skin specimens and may poses a diagnostic challenge as it may resemble other common benign lesions found in the head and neck region. We report a case of a 33-year old men presented to us with a pilomatrixoma of the right cheek, surgical management and histological findings.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":"27 1","pages":"28-32"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49507261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Resin Bonded Fixed Partial Denture (RBPFD) is a popular treatment for tooth preservation. Mechanical retention is a problem for RBFPD, where debonding is the main cause of failure. RBFPD preparation is minimal invasive. It removes undercut and tooth structure that supports retention so that single insertion guide can be achieved. This preparation was achieved by using surveyor on diagnostic cast, but there was a concern how to copy the surveyed cast to intraoral. Resin template method as a preparation guide was useful to avoid excessive tooth removal. RBFPD design was marked by using pencil on the diagnostic cast. The cast was surveyed to get the preparation designed and prepared by using milling device surveyor and burs. The template was made on the cast. Separator was applied and resin template was built along the margin until the occlusal line angle. The abutment teeth were etched and bonded. Bonding procedure was done on template. The template was placed on the teeth and polimerized. Abutment teeth preparation were done according to the cast with the bur contact simultaneously with the template’s margin and finishing line. Resin template has better accuration and adaptation, easier made and efficient, also prevent excessive tooth removal and control the preparation, mechanical retention can be achieved for RBFPD restoration longevity. Resin template is useful because preparation can be transfered from diagnostic cast to intraoral accurately.
{"title":"Resin Template for Guiding Preparation in Resin Bonded Fixed Partial Denture – A Case Report","authors":"Leni Hadi, H. Tamin, A. Yani, P. Ritonga","doi":"10.22452/adum.vol27no4","DOIUrl":"https://doi.org/10.22452/adum.vol27no4","url":null,"abstract":"Resin Bonded Fixed Partial Denture (RBPFD) is a popular treatment for tooth preservation. Mechanical retention is a problem for RBFPD, where debonding is the main cause of failure. RBFPD preparation is minimal invasive. It removes undercut and tooth structure that supports retention so that single insertion guide can be achieved. This preparation was achieved by using surveyor on diagnostic cast, but there was a concern how to copy the surveyed cast to intraoral. Resin template method as a preparation guide was useful to avoid excessive tooth removal. RBFPD design was marked by using pencil on the diagnostic cast. The cast was surveyed to get the preparation designed and prepared by using milling device surveyor and burs. The template was made on the cast. Separator was applied and resin template was built along the margin until the occlusal line angle. The abutment teeth were etched and bonded. Bonding procedure was done on template. The template was placed on the teeth and polimerized. Abutment teeth preparation were done according to the cast with the bur contact simultaneously with the template’s margin and finishing line. Resin template has better accuration and adaptation, easier made and efficient, also prevent excessive tooth removal and control the preparation, mechanical retention can be achieved for RBFPD restoration longevity. Resin template is useful because preparation can be transfered from diagnostic cast to intraoral accurately.","PeriodicalId":75515,"journal":{"name":"Annals of dentistry","volume":"27 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45489057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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