Pub Date : 2023-09-06DOI: 10.11648/j.bs.20230903.14
Suraj Adefabi Ogunyemi, Busayo Onafowoke Oguntola, O. Ogunlade
{"title":"The Roles of Echocardiography in Teaching of Cardiovascular Physiology at Pre-Clinical Level of Undergraduate Medical Education","authors":"Suraj Adefabi Ogunyemi, Busayo Onafowoke Oguntola, O. Ogunlade","doi":"10.11648/j.bs.20230903.14","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.14","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73965943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-28DOI: 10.11648/j.bs.20230903.12
Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, Musab Alsiddig Altayb, Mohammed Alhendi Ali, Amasi Abbas Idrees, Alaaeldeen Balal Ahmed
{"title":"Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State","authors":"Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, Musab Alsiddig Altayb, Mohammed Alhendi Ali, Amasi Abbas Idrees, Alaaeldeen Balal Ahmed","doi":"10.11648/j.bs.20230903.12","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.12","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74670322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-28DOI: 10.11648/j.bs.20230903.13
Yuri Pivovarenko
{"title":"Positively Charged Water as a Tumor Growth Stimulator","authors":"Yuri Pivovarenko","doi":"10.11648/j.bs.20230903.13","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.13","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73779306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-27DOI: 10.11648/j.bs.20230903.11
X. Tan, Jiajun Chen, Yuting Bai, Xin Chen
{"title":"Analysis of the Mechanism of <i>Salvia miltiorrhiza</i> in the Treatment of Pancreatic Cancer Based on Network Pharmacology","authors":"X. Tan, Jiajun Chen, Yuting Bai, Xin Chen","doi":"10.11648/j.bs.20230903.11","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.11","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87423778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-17DOI: 10.11648/j.bs.20230902.13
Dikosso Claire Astrid, Voundi-Voundi Esther, Well a Well a Koul Pascal Blaise, Moubitang Matomba Christine, Ntchimou Tochie Juliana Vinciane, Mbiandjeu Tchoumke Marius, Romaric de Manfouo Tuono, Fotsing Kwetche Pierre Rene
Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon
杜阿拉(喀麦隆沿海地区)性工作者乙型病毒性肝炎血清学状况及相关因素
{"title":"Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon)","authors":"Dikosso Claire Astrid, Voundi-Voundi Esther, Well a Well a Koul Pascal Blaise, Moubitang Matomba Christine, Ntchimou Tochie Juliana Vinciane, Mbiandjeu Tchoumke Marius, Romaric de Manfouo Tuono, Fotsing Kwetche Pierre Rene","doi":"10.11648/j.bs.20230902.13","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.13","url":null,"abstract":"Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"29 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88898667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-11DOI: 10.11648/j.bs.20230902.11
Kang Yi-fan, Gao Qing-zhuo, Yin Zhao-fang, Wang Zhi-hong, Liang Hui-zhi, Yang Yuan, Yang Pan, Duan Xia
{"title":"Comparison of Pregnancy Outcomes in Thyroid Antibody-Positive Women with Different Fertilization Methods","authors":"Kang Yi-fan, Gao Qing-zhuo, Yin Zhao-fang, Wang Zhi-hong, Liang Hui-zhi, Yang Yuan, Yang Pan, Duan Xia","doi":"10.11648/j.bs.20230902.11","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.11","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88511912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-11DOI: 10.11648/j.bs.20230902.12
Juliana Vinciane Ntchimou Tochie, Pascal Blaise Well a Well a Koul, Esther Voundi-Voundi, Claire Astrid Dikosso, Christine Moubitang Matomba, Marius Mbiandjeu Tchoumke, Romaric de Manfouo Tuono, Pierre Rene Fotsing Kwetche
{"title":"Serological Status of Hepatitis B Virus Among Pregnant Women in the Mifi District (West Cameroon)","authors":"Juliana Vinciane Ntchimou Tochie, Pascal Blaise Well a Well a Koul, Esther Voundi-Voundi, Claire Astrid Dikosso, Christine Moubitang Matomba, Marius Mbiandjeu Tchoumke, Romaric de Manfouo Tuono, Pierre Rene Fotsing Kwetche","doi":"10.11648/j.bs.20230902.12","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.12","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80868889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-31DOI: 10.11648/j.bs.20230901.15
Zongxin Li, Yihan Xiao, Yuanhai Zhou, Ting Tang, Ping Yang, Long Sun, Xiuji Cui
: Background: Hepatitis B virus (HBV) is the major cause of chronic hepatitis B, which can lead to liver cirrhosis and hepatocellular carcinoma. During HBV replication, splicing of viral RNA frequently occurs, and the spliced RNA or DNA has been reported to be related to the development of liver disease. HBV transcription is mainly regulated by core promoter ranging from nucleotide 1613 to 1849 and the A1762T/G1764A mutation, which can increase the viral transcription, is frequently detected in this region. Objective: The study aimed to analyze the effect of the A1762T/G1764A mutation in the core promoter of HBV on viral RNA splicing. Methods: The wild type (WT) and the A1762T/G1764A mutant HBV genome were cloned into the pCDNA3.1 vector, which was then transiently transfected into HepG2 cells. The intracellular HBV DNA and core protein were determined by the Southern blot and the Western blot, respectively. The relative level of HBSD was examined by quantitative PCR using TB green reagent. Results: the A1762T/G1764A mutation could enhance the ability of viral replication, however, had a minor effect on HBSD expression. Conclusion: The double mutation in CP could regulate the viral transcription, but was not involved in the viral RNA splicing.
{"title":"Hepatitis B Virus A1762T/G1764A Mutation Has a Minor Effect on the Viral Spliced DNA Expression","authors":"Zongxin Li, Yihan Xiao, Yuanhai Zhou, Ting Tang, Ping Yang, Long Sun, Xiuji Cui","doi":"10.11648/j.bs.20230901.15","DOIUrl":"https://doi.org/10.11648/j.bs.20230901.15","url":null,"abstract":": Background: Hepatitis B virus (HBV) is the major cause of chronic hepatitis B, which can lead to liver cirrhosis and hepatocellular carcinoma. During HBV replication, splicing of viral RNA frequently occurs, and the spliced RNA or DNA has been reported to be related to the development of liver disease. HBV transcription is mainly regulated by core promoter ranging from nucleotide 1613 to 1849 and the A1762T/G1764A mutation, which can increase the viral transcription, is frequently detected in this region. Objective: The study aimed to analyze the effect of the A1762T/G1764A mutation in the core promoter of HBV on viral RNA splicing. Methods: The wild type (WT) and the A1762T/G1764A mutant HBV genome were cloned into the pCDNA3.1 vector, which was then transiently transfected into HepG2 cells. The intracellular HBV DNA and core protein were determined by the Southern blot and the Western blot, respectively. The relative level of HBSD was examined by quantitative PCR using TB green reagent. Results: the A1762T/G1764A mutation could enhance the ability of viral replication, however, had a minor effect on HBSD expression. Conclusion: The double mutation in CP could regulate the viral transcription, but was not involved in the viral RNA splicing.","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90980728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-09DOI: 10.11648/j.bs.20230901.14
Kenneth Chinedu Ugoeze, Inderbir Singh Bakshi, Bruno Chukwuemeka Chinko, Kennedy Emeka Oluigbo, Ngozi Augustine Okoronkwo, Christian Arerusuoghene Alalor
{"title":"Phytopharmaceutical Benefits of Resveratrol in the Management of Diseases and Health Maintenance: A Review","authors":"Kenneth Chinedu Ugoeze, Inderbir Singh Bakshi, Bruno Chukwuemeka Chinko, Kennedy Emeka Oluigbo, Ngozi Augustine Okoronkwo, Christian Arerusuoghene Alalor","doi":"10.11648/j.bs.20230901.14","DOIUrl":"https://doi.org/10.11648/j.bs.20230901.14","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84472474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-09DOI: 10.11648/j.bs.20230901.13
Bruno Chukwuemeka Chinko, Onyinye Ukamaka Umeh
{"title":"Alterations in Lipid Profile and Oxidative Stress Markers Following Heat Stress on Wistar Rats: Ameliorating Role of Vitamin C","authors":"Bruno Chukwuemeka Chinko, Onyinye Ukamaka Umeh","doi":"10.11648/j.bs.20230901.13","DOIUrl":"https://doi.org/10.11648/j.bs.20230901.13","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76621451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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