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Further study on spectrophotometric determination of CO-Hb in post-mortem blood 死后血液中CO-Hb分光光度法测定的进一步研究
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90106-8
T. Hayashi, R. Nanikawa

The method for spectrophotometric determination of CO-Hb in blood on the basis of difference in absorbancies of deoxy- and carboxy-hemoglobin reported previously [1] was further improved. The total blood hemoglobin content was determined by the azide-methemoglobin method instead of the well-known cyanmethemoglobin method. This method was found to be useful even if applied to old or putrefied blood samples.

在前人报道的脱氧血红蛋白和羧化血红蛋白吸收率差异的基础上,进一步改进了分光光度法测定血中CO-Hb的方法。用叠氮-高铁血红蛋白法测定总血红蛋白含量,代替了常用的氰高铁血红蛋白法。这种方法被发现是有用的,即使适用于陈旧或腐烂的血液样本。
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引用次数: 1
Comparison of GLC-EMIT analysis for the assay of methadone and its major metabolite in urine GLC-EMIT法测定尿中美沙酮及其主要代谢物的比较
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90117-2
S.D. Ferrara, L. Tedeschi, F. Castagna, M. Marigo

The enzyme-multiplied immunoassay technique (EMIT) was compared with the gas-liquid chromatographic (GLC) method in the analysis of 130 urine samples from subjects receiving methadone treatment and non-methadone controls. The GC method allowed the quantitation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, the major metabolite of methadone. A good correlation was found between the two methods. The advantages of using the EMIT system are discussed.

对130份美沙酮治疗组和非美沙酮对照组的尿液样本,采用酶倍增免疫分析技术(EMIT)与气液色谱(GLC)法进行比较。气相色谱法测定了美沙酮的主要代谢物- 2-乙基-1,5-二甲基-3,3-二苯基吡咯烷。两种方法之间有很好的相关性。讨论了使用EMIT系统的优点。
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引用次数: 4
Concentration levels of endosulfan in biological material (report of three cases) 生物材料中硫丹的浓度水平(三例报告)
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90095-6
Antony Coutselinis, Pan. Kentarchou, Denis Boukis
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引用次数: 14
The identification of sympathomimetic amines by Raman spectroscopy 拉曼光谱法鉴定拟交感神经胺
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90093-2
Virginia C. Bass

This study was undertaken to explore the feasibility of using Raman spectroscopy as a means of identifying drugs in the forensic laboratory. Raman spectra of a group of sympathomimetic amines, in pure form and in pharmaceutical preparations, were obtained and compared; group similarities and individual differences were found, and satisfactory identifications could be made. Water solutions as well as solids were examined. The procedure is rapid, sensitive, simple, and non-destructive.

本研究旨在探讨在法医实验室中使用拉曼光谱作为鉴定药物的一种手段的可行性。获得并比较了纯形式和药物制剂中一类拟交感神经胺的拉曼光谱;发现了群体相似性和个体差异,并能做出令人满意的鉴定。测试了水溶液和固体。该方法快速、灵敏、简便、无破坏性。
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引用次数: 7
Current approaches in toxicology 1977 目前的毒理学方法1977
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90098-1
Charles L. Winek
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引用次数: 0
The roles of corneal mucopolysaccharides and water contents in post-mortem corneal clouding 角膜粘多糖和水分含量在死后角膜混浊中的作用
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90101-9
Shigeyuki Tsunenari, Mizuho Kanda

The quantitative changes in mucopolysaccharides (MPS) and water contents in post-mortem rabbit corneas were studied. On the basis of the results, the post-mortem periods were classified into 4 stages. The first stage was during the first day after death when the MPS and the corneal water contents were observed to have maintained their initial values and the cornea was “clear”. The second was 1 to 3 days after death when the MPS remained at approximately their initial value, whereas the water contents were very pronounced. In this second stage the cornea was “a little clear” or “cloudy”. The third was 3 to 6 days after death when the MPS were found to have decreased gradually, but the water contents maintained their high level. The cornea in this third stage was “cloudy” or “very cloudy”. The fourth was 6 or more days after death when the two parameters were found to have decreased significantly, and the cornea was “very cloudy”.

研究了兔死后角膜中粘多糖(MPS)和水分含量的定量变化。在此基础上,将死亡时间划分为4个阶段。第一阶段是死后第一天,观察到MPS和角膜含水量保持初始值,角膜“清澈”。第二次是死后1至3天,MPS保持在大约初始值,而含水量非常明显。在第二阶段,角膜“有点清澈”或“浑浊”。第三期为死后3 ~ 6天,MPS逐渐下降,但含水量维持在较高水平。第三期角膜呈“浑浊”或“非常浑浊”。第四次是在死亡后6天或更长时间,发现这两项参数明显下降,角膜“非常浑浊”。
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引用次数: 0
Problem of the identification of typewriter makes and models 打字机品牌和型号的识别问题
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90088-9
Jacques Mathyer

In this paper, the author studies the generalities of the problem of a typewriting machine identification from a text. He outlines in detail the identification systems which are commercially available, the “Atlas der Schreibmaschinenschrift Pica” from Josef Haas (German) and the “System for Identification of Typewriter Makes Using the Card Index” distributed by the General Secretariat of I.C.P.O.—Interpol. He comments briefly on two well-known systems: that of G. de la Durantaye of Toronto, Canada, and that of D. A. Crown from Washington, D.C., U.S.A. Finally, the author proposes a working method and exposes the limits of the identification possibilities.

本文研究了打字机文本识别问题的一般性质。他详细概述了商业上可获得的识别系统,约瑟夫·哈斯(德语)的“Pica图集”和国际刑警组织总秘书处分发的“使用卡片索引识别打字机产品系统”。他简要评述了加拿大多伦多的G. de la Durantaye和美国华盛顿特区的D. a . Crown两种著名的系统。最后,作者提出了一种工作方法,并揭示了识别可能性的局限性。
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引用次数: 1
Observations on the use of an autoanalyser and a manual technique for the detection of the red cell antigens C, D, E, c, K and S in bloodstains 血渍中红细胞抗原C、D、E、C、K、S的自动分析仪和手工检测技术的应用观察
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90110-X
M.J. McDowall, P.J. Lincoln, B.E. Dodd

The results of the detection of the Rh antigens (D, C, E, c) and the S and K antigens by an elution technique comparing the AutoAnalyser and a manual method for the detection of eluted antibody are presented. Investigation of a series of anti-D sera demonstrates that while it is not too difficult to select antisera for the detection of the D antigen in fresh stains (i.e. up to 4 weeks old) some of these sera will not be satisfactory for typing older stains. The AutoAnalyser system used is low ionic strength/polybrene which has a capacity for detecting 0.002 μg/ml of anti-D, but in spite of this degree of sensitivity the manual technique for the detection of eluted antibody compared very favourably and tended, where older stains were being tested, to give more conclusive results than the AutoAnalyser. The superiority of the manual technique was most pronounced when detecting the S and K antigens.

本文介绍了用自动分析仪和手工方法对Rh抗原(D、C、E、C)和S、K抗原进行洗脱检测的结果。对一系列抗D血清的调查表明,虽然在新鲜染色(即4周以内)中选择用于检测D抗原的抗血清并不太困难,但其中一些血清对于旧有染色的分型并不令人满意。使用的autoanalyzer系统是低离子强度/聚烯烃,具有检测0.002 μg/ml抗d的能力,但尽管有这种程度的灵敏度,人工技术用于洗脱抗体的检测相比非常有利和倾向,在旧的染色被测试时,给出比autoanalyzer更确凿的结果。手工技术的优越性在检测S和K抗原时最为明显。
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引用次数: 0
A lethal complication to gastric lavage leading to malpractice suit: A case report 洗胃导致医疗事故诉讼的致命并发症一例报告
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90091-9
A. Fiori, G. Cecchetti, G.V. Giusti

A case of gastric lavage suffocation after petroleum poisoning is described, together with the peculiar analytical techniques that were employed and the juridical aspects of medical malpractice to which it gave rise.

本文描述了一起石油中毒后洗胃窒息的病例,以及所采用的特殊分析技术和由此引起的医疗事故的法律方面。
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引用次数: 8
Cyanide poisoning as a mode of suicide 氰化物中毒作为一种自杀方式
Pub Date : 1978-01-01 DOI: 10.1016/0379-0738(78)90092-0
C.L. Winek, E. Fusia, W.D. Collom, S.P. Shanor

A five-year survey (1970–1975) of suicides was conducted in a county of 1,800,000 population. Cyanide is readily available in various forms, lethal in minute quantities and rapidly acting. Out of 700 suicides, six employed cyanide poisoning as an active manner of death.

一项为期五年(1970-1975)的自杀调查在一个拥有180万人口的县进行。氰化物很容易以各种形式获得,少量就能致命,而且作用迅速。在700名自杀者中,有6人将氰化物中毒作为主动死亡方式。
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引用次数: 21
期刊
Forensic science
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