Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1936420
N. El-Sherbiny, Eman H. Ibrahim, Nashwa Sayed
ABSTRACT Background: Patient-centered care has been considered the foundation of healthcare quality and the core competency of the doctor-patient relationship. Aims: To assess the attitudes of medical students toward a patient-centered approach and identify the predictors of patient-centeredness scores. Methods: A cross-sectional study was carried out in Fayoum Medical School/Egypt using a validated Arabic version of the Patient-Practitioner Orientation Scale (PPOS). Results: The total PPOS score showed variable score as the grades move up. The total PPOS ranged from 0.05 to 4.39 with an average score of (2.71 ± 0.66) for the entire sample. The sharing and caring subscale score ranged from 0.56 to 4.44 and 0.44 to 5.33 with an average score of (2.33 ± 0.49) and (3.09 ± 0.92) respectively. Conclusion: Medical students had low patient-centered attitude. Medical curricula should be redesigned, and medical students may also benefit from engagement in patient healthcare service.
{"title":"Medical students’ attitudes towards patient-centered care, Fayoum Medical School, Egypt","authors":"N. El-Sherbiny, Eman H. Ibrahim, Nashwa Sayed","doi":"10.1080/20905068.2021.1936420","DOIUrl":"https://doi.org/10.1080/20905068.2021.1936420","url":null,"abstract":"ABSTRACT Background: Patient-centered care has been considered the foundation of healthcare quality and the core competency of the doctor-patient relationship. Aims: To assess the attitudes of medical students toward a patient-centered approach and identify the predictors of patient-centeredness scores. Methods: A cross-sectional study was carried out in Fayoum Medical School/Egypt using a validated Arabic version of the Patient-Practitioner Orientation Scale (PPOS). Results: The total PPOS score showed variable score as the grades move up. The total PPOS ranged from 0.05 to 4.39 with an average score of (2.71 ± 0.66) for the entire sample. The sharing and caring subscale score ranged from 0.56 to 4.44 and 0.44 to 5.33 with an average score of (2.33 ± 0.49) and (3.09 ± 0.92) respectively. Conclusion: Medical students had low patient-centered attitude. Medical curricula should be redesigned, and medical students may also benefit from engagement in patient healthcare service.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"188 - 193"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1936420","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48627563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1959259
Ahmed H. Hashish, Noha S. Elshaer, Dorria E. Meleis
The production of carbon black (CB) has been considered as one of the top 50 industrial chemicals manufactured worldwide. Working in CB manufacturing process might pose a cardiovascular risk. This ...
{"title":"Removal Statement","authors":"Ahmed H. Hashish, Noha S. Elshaer, Dorria E. Meleis","doi":"10.1080/20905068.2021.1959259","DOIUrl":"https://doi.org/10.1080/20905068.2021.1959259","url":null,"abstract":"The production of carbon black (CB) has been considered as one of the top 50 industrial chemicals manufactured worldwide. Working in CB manufacturing process might pose a cardiovascular risk. This ...","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"224 - 224"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60071314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1938425
M. Agrawal, Preeti Singh, Usha Joshi
ABSTRACT Background All drugs profoundly modify our biological processes and may manifest as adverse drug reactions (ADRs), which are unpredictable and inevitable consequences. Antibiotics are a common cause of ADR, necessitating stopping or change of antibiotics. The incidence of ADRs increases with the number of drugs prescribed in a prescription, and antibiotics are rarely prescribed as monotherapy. Aim The study aimed to assess frequency, class of antibiotics, symptoms, causality, the severity of antimicrobial-associated ADRs, and see the demographic distribution. Methods ADRs were collected and filled in suspected ADR forms and sent via vigiflow to the National Coordination Centre-Pharmacovigilance Programme of India (NCC-PvPI). These ADR reports, termed individual case safety reports (ICSRs), were analyzed from Jan 2016 to Dec 2019. Results A total of 414 (54.33%) ICSRs of 762 were identified as antimicrobial-associated. Adults in the age group 19–65 years accounted for 345 (83.09%) of ADRs. A total of 192 (46.38%) were males, and 222 (53.14%) were females. Skin and subcutaneous tissue System organ class was involved in 54% of cases. In the causality assessment, 268 (64.49%) were “probable,” 123 (29.71%) were “possible,” and 23 (5.56%) were “certain.” On severity assessment, 256 ADRs (61.83%) were mild, 133 (32.12%) were moderate, and 25 (6.03%) were severe. A total of 54 antimicrobial agents, excluding anti-tubercular drugs, were identified, and antibacterial accounted for 268 (64.73%) ADRs, followed by antiviral 90 (21.73%), antiprotozoal agents 33 (7.97%) antimalarials anti-scabicidal, antifungal accounting for the remaining. Conclusion Antimicrobials play a crucial role in treating infections, and utmost vigilance during antimicrobials prescription reduces the frequency and severity of the ADRs, thereby reducing the morbidity and mortality and the pharmacoeconomic burden to the health care system. Pharmacovigilance must be boosted to ensure the safe and effective use of antibiotics and reduce the occurrence of ADRs.
{"title":"Antimicrobials associated adverse drug reaction profiling: a four years retrospective study (Pharmacovigilance study)","authors":"M. Agrawal, Preeti Singh, Usha Joshi","doi":"10.1080/20905068.2021.1938425","DOIUrl":"https://doi.org/10.1080/20905068.2021.1938425","url":null,"abstract":"ABSTRACT Background All drugs profoundly modify our biological processes and may manifest as adverse drug reactions (ADRs), which are unpredictable and inevitable consequences. Antibiotics are a common cause of ADR, necessitating stopping or change of antibiotics. The incidence of ADRs increases with the number of drugs prescribed in a prescription, and antibiotics are rarely prescribed as monotherapy. Aim The study aimed to assess frequency, class of antibiotics, symptoms, causality, the severity of antimicrobial-associated ADRs, and see the demographic distribution. Methods ADRs were collected and filled in suspected ADR forms and sent via vigiflow to the National Coordination Centre-Pharmacovigilance Programme of India (NCC-PvPI). These ADR reports, termed individual case safety reports (ICSRs), were analyzed from Jan 2016 to Dec 2019. Results A total of 414 (54.33%) ICSRs of 762 were identified as antimicrobial-associated. Adults in the age group 19–65 years accounted for 345 (83.09%) of ADRs. A total of 192 (46.38%) were males, and 222 (53.14%) were females. Skin and subcutaneous tissue System organ class was involved in 54% of cases. In the causality assessment, 268 (64.49%) were “probable,” 123 (29.71%) were “possible,” and 23 (5.56%) were “certain.” On severity assessment, 256 ADRs (61.83%) were mild, 133 (32.12%) were moderate, and 25 (6.03%) were severe. A total of 54 antimicrobial agents, excluding anti-tubercular drugs, were identified, and antibacterial accounted for 268 (64.73%) ADRs, followed by antiviral 90 (21.73%), antiprotozoal agents 33 (7.97%) antimalarials anti-scabicidal, antifungal accounting for the remaining. Conclusion Antimicrobials play a crucial role in treating infections, and utmost vigilance during antimicrobials prescription reduces the frequency and severity of the ADRs, thereby reducing the morbidity and mortality and the pharmacoeconomic burden to the health care system. Pharmacovigilance must be boosted to ensure the safe and effective use of antibiotics and reduce the occurrence of ADRs.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"177 - 187"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1938425","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44109758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1885953
Yasser Essam Elfeil, Ahmed Mohammed Alattar, T. Ghoneim, A. Abd Elaziz, E. Deghidy
ABSTRACT Introduction: Hypotension is the most frequent consequence of spinal anesthesia in cesarean section. It results in harmful effects on mother and newborn. Aim: This study aim was to evaluate the correlation of positional changes in hemodynamic (heart rate and blood pressure) measured before spinal anesthesia in anticipation of occurrence of hypotension throughout cesarean delivery. Methods: 100 ASA grade I parturient were selected for this prospective observational study. Preoperative sociodemographic data, parity, and hemodynamic parameters were recorded including changes in systolic, diastolic, mean arterial blood pressure, and heart rate after positional shift from supine to lateral and sitting positions. Intraoperative, occurrence of hypotension was noted. Results: With hypotension as the dependent variable, the age, parity, heart rate at supine position, and changes in (heart rate, systolic, diastolic and mean arterial blood pressure) from supine to lateral position, and from supine to sitting position had high statistical significant negative correlation with blood pressure as P value <.05. Multivariate logistic analysis to assess predictors of hypotension concluded that changes in hemodynamic variable from supine to lateral position only significant predictor were (∆ heart rate, ∆ diastolic and ∆ mean blood pressure), and changes in hemodynamic variable from supine to sitting position only significant predictor were (∆heart rate and ∆ diastolic blood pressure). Discussion: Elevated sympathetic activity before neuraxial anesthesia was associated with higher risk for post-spinal hypotension. The great variability in hemodynamic after positional change indicates higher sympathetic activity to blood vessels. The high rise in the autonomic activity, the higher the risk for post-spinal hypotension Conclusion: Age, parity, and positional changes in hemodynamic were correlated with blood pressure reading after spinal anesthesia during cesarean delivery.
{"title":"The Effectiveness Of Non Invasive Hemodynamic Parameters In Detection Of Spinal Anesthesia Induced Hypotension During Cesarean Section","authors":"Yasser Essam Elfeil, Ahmed Mohammed Alattar, T. Ghoneim, A. Abd Elaziz, E. Deghidy","doi":"10.1080/20905068.2021.1885953","DOIUrl":"https://doi.org/10.1080/20905068.2021.1885953","url":null,"abstract":"ABSTRACT Introduction: Hypotension is the most frequent consequence of spinal anesthesia in cesarean section. It results in harmful effects on mother and newborn. Aim: This study aim was to evaluate the correlation of positional changes in hemodynamic (heart rate and blood pressure) measured before spinal anesthesia in anticipation of occurrence of hypotension throughout cesarean delivery. Methods: 100 ASA grade I parturient were selected for this prospective observational study. Preoperative sociodemographic data, parity, and hemodynamic parameters were recorded including changes in systolic, diastolic, mean arterial blood pressure, and heart rate after positional shift from supine to lateral and sitting positions. Intraoperative, occurrence of hypotension was noted. Results: With hypotension as the dependent variable, the age, parity, heart rate at supine position, and changes in (heart rate, systolic, diastolic and mean arterial blood pressure) from supine to lateral position, and from supine to sitting position had high statistical significant negative correlation with blood pressure as P value <.05. Multivariate logistic analysis to assess predictors of hypotension concluded that changes in hemodynamic variable from supine to lateral position only significant predictor were (∆ heart rate, ∆ diastolic and ∆ mean blood pressure), and changes in hemodynamic variable from supine to sitting position only significant predictor were (∆heart rate and ∆ diastolic blood pressure). Discussion: Elevated sympathetic activity before neuraxial anesthesia was associated with higher risk for post-spinal hypotension. The great variability in hemodynamic after positional change indicates higher sympathetic activity to blood vessels. The high rise in the autonomic activity, the higher the risk for post-spinal hypotension Conclusion: Age, parity, and positional changes in hemodynamic were correlated with blood pressure reading after spinal anesthesia during cesarean delivery.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"121 - 129"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1885953","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42957986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1874632
Irem Akova, Öznur Hasdemir, Esma Kiliç
ABSTRACT Background The aim of this study was to evaluate the relationship between burnout, depression, anxiety, and stress levels of primary health-care workers. Methods This cross-sectional study included 338 health-care workers. The sociodemographic data form, the Maslach Burnout Inventory (MBI), and the Depression Anxiety Stress Scale-21 (DASS-21) were applied. Mann Whitney U test, Kruskal Wallis test, Chi square test, and Logistic regression analysis were used. The error level was taken as 0.05. Results The burnout levels of the health workers were lower level in Emotional Exhaustion (EE) (79.0%), Depersonalization (D) (81.1%), and Personal Accomplishment (PA) (54.1%). The level of the depression, anxiety, and stress were found to be 10.9%, 14.8%, and 5.0%, respectively. The rates of low-moderate-high EE and D, low-moderate PA were higher in physicians than midwives and nurses. There were significant differences between the mean of burnout levels and gender, marital status, occupation, and total working times. Mean depression was higher among physicians while mean stress was lower among who worked 5 years and under. EE and PA were the factors associated with depression and anxiety, while EE was the factor associated with stress. Discussion Considering that burnout, depression, anxiety, and stress are intertwined concepts, it is thought that's needed to develop strategies for health workers to regain working energy.
{"title":"Evaluation of the relationship between burnout, depression, anxiety, and stress levels of primary health-care workers (Center Anatolia)","authors":"Irem Akova, Öznur Hasdemir, Esma Kiliç","doi":"10.1080/20905068.2021.1874632","DOIUrl":"https://doi.org/10.1080/20905068.2021.1874632","url":null,"abstract":"ABSTRACT Background The aim of this study was to evaluate the relationship between burnout, depression, anxiety, and stress levels of primary health-care workers. Methods This cross-sectional study included 338 health-care workers. The sociodemographic data form, the Maslach Burnout Inventory (MBI), and the Depression Anxiety Stress Scale-21 (DASS-21) were applied. Mann Whitney U test, Kruskal Wallis test, Chi square test, and Logistic regression analysis were used. The error level was taken as 0.05. Results The burnout levels of the health workers were lower level in Emotional Exhaustion (EE) (79.0%), Depersonalization (D) (81.1%), and Personal Accomplishment (PA) (54.1%). The level of the depression, anxiety, and stress were found to be 10.9%, 14.8%, and 5.0%, respectively. The rates of low-moderate-high EE and D, low-moderate PA were higher in physicians than midwives and nurses. There were significant differences between the mean of burnout levels and gender, marital status, occupation, and total working times. Mean depression was higher among physicians while mean stress was lower among who worked 5 years and under. EE and PA were the factors associated with depression and anxiety, while EE was the factor associated with stress. Discussion Considering that burnout, depression, anxiety, and stress are intertwined concepts, it is thought that's needed to develop strategies for health workers to regain working energy.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"52 - 60"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1874632","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41885159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1904547
Ahmed A. Elhadidy, S. Mashal
ABSTRACT Introduction: Obesity is arising health problem that is linked to many pathological conditions. Treatment of obesity has a beneficial effect on many health problems. Little data available about effect of weight loss on prediabetes. Object: To evaluate the effect of intra gastric balloon (IGB) as obesity treatment on prediabetes. Method: In a prospective study we have followed 42 obese prediabetic patients who used IGB as obesity treatment. All patients were evaluated for anthropometric measures, lipid profile, fasting blood glucose (FBG), postprandial blood glucose (PPBG) and glycosylated hemoglobin HbA1c before and 6 months after IGB insertion. Results: There was a significant reduction in body weight, waist–hip ratio and also body mass index (BMI), as by time of balloon removal mean body weight was 86.62 ± 7.84 Kg, and mean BMI at time of removal was 29.48 ± 2.31 kg/m2 compared to 99.10 ± 7.34 Kg and 33.61 ± 2.18 Kg/m2 before balloon insertion (p < 0.05). Also, significant improvement of FBG and PPBG with mean value of FBG 93.00 ± 9.12 mg% and mean level of PPBG 133.31 ± 11.68 mg% compared to FBG 110.71 ± 12.10 mg% and PPBG 166.81 ± 18.82 mg% before balloon insertion (p < 0.05), likewise there was a significant reduction in HbA1c as its mean value has become 5.48 ± 0.35 compared to 6.01 ± 0.21 before balloon insertion (p < 0.05). Conclusions: six months treatment with IGB for obesity improved the prediabetic condition that may prevent or at least delay type II diabetes mellitus, which needs longer follow-up.
{"title":"The impact of intra gastric balloon as a treatment of obesity on pre-diabetes in obese persons","authors":"Ahmed A. Elhadidy, S. Mashal","doi":"10.1080/20905068.2021.1904547","DOIUrl":"https://doi.org/10.1080/20905068.2021.1904547","url":null,"abstract":"ABSTRACT Introduction: Obesity is arising health problem that is linked to many pathological conditions. Treatment of obesity has a beneficial effect on many health problems. Little data available about effect of weight loss on prediabetes. Object: To evaluate the effect of intra gastric balloon (IGB) as obesity treatment on prediabetes. Method: In a prospective study we have followed 42 obese prediabetic patients who used IGB as obesity treatment. All patients were evaluated for anthropometric measures, lipid profile, fasting blood glucose (FBG), postprandial blood glucose (PPBG) and glycosylated hemoglobin HbA1c before and 6 months after IGB insertion. Results: There was a significant reduction in body weight, waist–hip ratio and also body mass index (BMI), as by time of balloon removal mean body weight was 86.62 ± 7.84 Kg, and mean BMI at time of removal was 29.48 ± 2.31 kg/m2 compared to 99.10 ± 7.34 Kg and 33.61 ± 2.18 Kg/m2 before balloon insertion (p < 0.05). Also, significant improvement of FBG and PPBG with mean value of FBG 93.00 ± 9.12 mg% and mean level of PPBG 133.31 ± 11.68 mg% compared to FBG 110.71 ± 12.10 mg% and PPBG 166.81 ± 18.82 mg% before balloon insertion (p < 0.05), likewise there was a significant reduction in HbA1c as its mean value has become 5.48 ± 0.35 compared to 6.01 ± 0.21 before balloon insertion (p < 0.05). Conclusions: six months treatment with IGB for obesity improved the prediabetic condition that may prevent or at least delay type II diabetes mellitus, which needs longer follow-up.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"110 - 112"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1904547","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44245527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1911111
A. Davies, Sherif M Wilson
To quote Thompson: “all cleft lip surgeons have their favorite surgical technique for repairing the unilateral cleft lip. It is usually a hybrid of training experience and imagination.” [1] Of the ...
{"title":"Invited commentary on: comparative study between Fisher anatomical subunit approximation technique and Millard rotation-advancement technique in unilateral cleft lip repair","authors":"A. Davies, Sherif M Wilson","doi":"10.1080/20905068.2021.1911111","DOIUrl":"https://doi.org/10.1080/20905068.2021.1911111","url":null,"abstract":"To quote Thompson: “all cleft lip surgeons have their favorite surgical technique for repairing the unilateral cleft lip. It is usually a hybrid of training experience and imagination.” [1] Of the ...","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"137 - 138"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1911111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49419507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1995284
M. Gamaleldin, Y. Naga, A. I. Ellakany, E. Nassar
ABSTRACT Introduction Essential Hypertension has been a great burden on public health services for a long time, with many life-threatening complications. Therefore, we decided to study Atrial Natriuretic peptide (ANP) gene expression as one of the most important blood pressure controlling genes, in order to use ANP gene as a potential diagnostic or therapeutic marker in the near future. Methods One hundred essential hypertensive patients and 100 normotensive controls were included. Study Subjects were subjected to ANP gene expression analysis, together with blood pressure measurement, Lab investigations, and BMI analysis. Results There was a statistical difference between ANP gene expression and blood pressure, with lower ANP gene expression level (median of 0.3) being present among hypertensive patients and higher ANP gene expression level (median of 1.6) among normotensive controls (p < 0.001). Discussion We proved that ANP gene expression to be low in essential hypertension patients compared with normotensive individuals.
{"title":"Role of expression of atrial natriuretic peptide gene in essential hypertension among Egyptian patients","authors":"M. Gamaleldin, Y. Naga, A. I. Ellakany, E. Nassar","doi":"10.1080/20905068.2021.1995284","DOIUrl":"https://doi.org/10.1080/20905068.2021.1995284","url":null,"abstract":"ABSTRACT Introduction Essential Hypertension has been a great burden on public health services for a long time, with many life-threatening complications. Therefore, we decided to study Atrial Natriuretic peptide (ANP) gene expression as one of the most important blood pressure controlling genes, in order to use ANP gene as a potential diagnostic or therapeutic marker in the near future. Methods One hundred essential hypertensive patients and 100 normotensive controls were included. Study Subjects were subjected to ANP gene expression analysis, together with blood pressure measurement, Lab investigations, and BMI analysis. Results There was a statistical difference between ANP gene expression and blood pressure, with lower ANP gene expression level (median of 0.3) being present among hypertensive patients and higher ANP gene expression level (median of 1.6) among normotensive controls (p < 0.001). Discussion We proved that ANP gene expression to be low in essential hypertension patients compared with normotensive individuals.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"240 - 246"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42759504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1892306
Nivine Abou Dargham, Youssef Sultan, O. Mourad, Mariam Baidoun, Omar Aboul Hosn, Azza Abou El Naga, H. Bahmad, Bilal Azakir
ABSTRACT Background Inadequate use of statistics in biomedical research might not only affect science but also harm human beings if applied in medical practice. Biostatistics is fundamental to improve understanding and appraising of evidence-based medicine (EBM); yet, it is still not well understood and appreciated by medical students. Therefore, early exposure of medical students and physicians-in-training to research tools including Biostatistics is of utmost importance. Objective The aim of this study is to determine the perception of Biostatistics by medical students at a private medical school in Beirut, Lebanon, and to identify its best implementation time in the medical curriculum. Methods This is a cross-sectional study based on a self-administered questionnaire distributed among medical students in their pre-clerkship years (first three years of a 6-year program) who undertook Biostatistics. The assessment of perception was based on the 5-point Likert scale anchored by Strongly disagree = 1 and Strongly agree = 5 including 36 questions distributed into four domains to assess the course value, difficulty, behavioral, and expectations. Results 186 of 269 students responded to the questionnaire, yielding a response rate of 69.14%. Around 60% of students declared that the knowledge gained from biostatistics courses is useful to their future career, and almost 70% understood the main concepts of biostatistics. 57.7% of students perceived that lack of practicing exercises might contribute to making the course more difficult. The mean score of domains was higher in females but did not significantly differ within the three academic years. Only 35.1% of the students positively perceived the importance of biostatistics modules, mostly third-year students. Conclusion Although the majority of medical students perceived biostatistics modules negatively, they were aware of the relevance of biostatistics to their medical career and real-life health issues.
{"title":"Perception of Biostatistics by Lebanese Medical Students: A Cross-Sectional Study","authors":"Nivine Abou Dargham, Youssef Sultan, O. Mourad, Mariam Baidoun, Omar Aboul Hosn, Azza Abou El Naga, H. Bahmad, Bilal Azakir","doi":"10.1080/20905068.2021.1892306","DOIUrl":"https://doi.org/10.1080/20905068.2021.1892306","url":null,"abstract":"ABSTRACT Background Inadequate use of statistics in biomedical research might not only affect science but also harm human beings if applied in medical practice. Biostatistics is fundamental to improve understanding and appraising of evidence-based medicine (EBM); yet, it is still not well understood and appreciated by medical students. Therefore, early exposure of medical students and physicians-in-training to research tools including Biostatistics is of utmost importance. Objective The aim of this study is to determine the perception of Biostatistics by medical students at a private medical school in Beirut, Lebanon, and to identify its best implementation time in the medical curriculum. Methods This is a cross-sectional study based on a self-administered questionnaire distributed among medical students in their pre-clerkship years (first three years of a 6-year program) who undertook Biostatistics. The assessment of perception was based on the 5-point Likert scale anchored by Strongly disagree = 1 and Strongly agree = 5 including 36 questions distributed into four domains to assess the course value, difficulty, behavioral, and expectations. Results 186 of 269 students responded to the questionnaire, yielding a response rate of 69.14%. Around 60% of students declared that the knowledge gained from biostatistics courses is useful to their future career, and almost 70% understood the main concepts of biostatistics. 57.7% of students perceived that lack of practicing exercises might contribute to making the course more difficult. The mean score of domains was higher in females but did not significantly differ within the three academic years. Only 35.1% of the students positively perceived the importance of biostatistics modules, mostly third-year students. Conclusion Although the majority of medical students perceived biostatistics modules negatively, they were aware of the relevance of biostatistics to their medical career and real-life health issues.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"103 - 109"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1892306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44037221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/20905068.2021.1880042
A. Khalaf
ABSTRACT Introduction:Inguinal hernia is the most commonly hernia in both men and women but occurs more common in men. Although there are two basic types of inguinal hernia with differences in anatomy, the etiology, complications, and surgical repair technique of both are very similar. The aim of this study was to evaluate the demographic and clinical characteristics of patients with inguinal hernia who underwent either elective or emergency surgical hernia repair at Al-Basra Teaching Hospital. Methods: This was a prospective clinical study involving patients with inguinal hernia admitted to Al-Basra Teaching Hospital from February 2017to November 2019. Patient’s demographic data, smoking habit, body mass index, history of chronic diseases, family history of inguinal hernia, and post-operative complications were evaluated. The patients were divided into seven groups according to age. All data were recorded and analyzed. Results: A total of 250 patients age 16 to 82 years were included (men, 88.4%, women, 11.6%) in this study. Most of the patients were above the age of 40, nearly half of the patients were smokers and had a positive family history of inguinal hernia. Most patients had normal body weight, and 12% of patients developed postoperative complications. Conclusion: We concluded that a large proportion of patients with inguinal hernia were men and they underwent elective hernia repair. All of patients with recurrent hernia were found to be smokers. Patient who underwent elective hernia repair had minimal postoperative complications with short hospitalization.
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