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Role of the lung function test in asthmatic children admitted to Al-Azhar University (Assiut) 肺功能检查在爱资哈尔大学(Assiut)哮喘患儿中的作用
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_42_21
A. Hamed, M. Mohammed, K. Awad, Y. Abdel-Rahman
Background and aim Lung function, especially spirometry, is an important investigatory tool in the evaluation of asthma in children. This study aimed to compare the clinical condition of asthmatic children using the lung function test before and after treatment and after 3 months as a follow-up of asthmatic patients admitted to Al-Azhar Assiut University Hospital. Patients and methods This clinical study was a prospective study that included 60 asthmatic children aged 6–16 years with bronchial asthma plus 30 children matched for age, sex and nutritional status as a control group over a period of 13 months from December 1, 2019 to December 31, 2020. Results The age of the children included in this study was found to be mean±SD 9.033±2.843, with a male predominance (male : female ratio 58% : 42%) and a positive family history of asthma (61%) and other allergic disorders (65%). There was a statistically significant change in forced expiratory volume at first second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio that showed considerable improvement in both age groups at admission, after receiving the suitable treatment and at follow-up 3 months after discharge. Conclusion Pediatric asthma is a major clinical concern and represents a huge burden on the family and society, hence the importance of prompt and early diagnosis that includes lung function testing, especially FEV1, FVC, and FEV1/FVC ratio, in not only diagnosis but also for monitoring the efficacy of treatment and follow-up.
背景与目的肺功能,尤其是肺活量测定是评估儿童哮喘的重要调查工具。本研究旨在比较哮喘患儿治疗前后及随访3个月后肺功能检查的临床情况,作为对爱资哈尔阿西尤特大学医院哮喘患儿的随访。患者与方法本临床研究是一项前瞻性研究,于2019年12月1日至2020年12月31日为期13个月,纳入60名6-16岁支气管哮喘患儿和30名年龄、性别和营养状况匹配的儿童作为对照组。结果本组患儿年龄均值±SD为9.033±2.843,男性为主(男女比例58%:42%),有哮喘家族史(61%)和其他过敏性疾病家族史(65%)。两组患者入院时、接受适当治疗后及出院后3个月随访时第一秒用力呼气量(FEV1)、用力肺活量(FVC)、FEV1/FVC比值均有显著改善,差异均有统计学意义。结论儿童哮喘是临床关注的主要问题,给家庭和社会带来了巨大的负担,因此及时早期诊断,包括肺功能检测,特别是FEV1、FVC、FEV1/FVC比值,不仅对诊断有重要意义,对监测治疗效果和随访也有重要意义。
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引用次数: 0
Achievement of a 136-day delayed-interval delivery of a second twin with minimum intervention 在最小干预下实现136天延迟间隔分娩第二个双胞胎
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_9_22
Aziza H. Nassef, Doaa S. Ahmed, Medhat Abd Elwahab
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引用次数: 0
Spleen stiffness measurement based on shear-wave elastography for noninvasive assessment of esophageal varices in liver cirrhosis cases 基于剪切波弹性成像的脾脏刚度测量在肝硬化食管静脉曲张无创评估中的应用
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_16_21
Walid N. Soliman, K. Eid, A. Mohammad
Background and aim Several laboratory tests and procedures have been considered as noninvasive prediction of esophageal varices (OV). This study assessed the usefulness of shear-wave elastography in splenic stiffness measurement (SSM) as a noninvasive assessment for OV prediction. Patients and methods This study was performed on 100 cases in Sohag Cardiology and Gastroenterology 1Center who were categorized into three groups: group A: (n=40) included liver cirrhosis of any cause proved clinically, laboratory, and by ultrasound; group B: (n=30) included chronic hepatitis of any cause; and group C: (n=30) included nonhepatic cases attending the hospital with gastrointestinal tract complaints. All cases have been subjected to full history taking and clinical examination before classification, complete blood count, alanine aminotransferase, aspartate transaminase, serum albumin, coagulation profile and serum bilirubin, hepatitis C virus antibody (HCV Ab) and hepatitis B surface antigen (HB Ag), abdominal ultrasonography, SSM by shear-wave elastography, and upper endoscopy for diagnosing of OV. Results As regards to abdominal ultrasound and upper endoscopy, significant differences were noted between three groups regarding spleen, spleen diameter, SSM, ascites, and OV (as 27.5 and 65% cases in group I had ascites and OV versus no cases in groups II and III as P<0.001). As regards to spleen diameter and SSM, significant increase was noted in group A than B and C, but insignificant differences were noted among groups B and C. As regards to OV grades in group A, there were five cases with grade I, nine cases with grade II, five cases with grade III, and seven cases with grade IV. Considerable positive correlations were noted among OV grades and acoustic radiation force impulse elastography (r=0.904, P <0.001). Conclusion SSM by shear-wave elastography is a useful noninvasive parameter for detection of OV presence and grading in cases of liver cirrhosis.
背景与目的一些实验室检查和程序被认为是食管静脉曲张(OV)的无创预测。本研究评估了剪切波弹性成像在脾刚度测量(SSM)中作为OV预测的无创评估的有效性。患者和方法本研究对Sohag心脏病和胃肠病学1中心的100例患者进行了研究,分为三组:A组:(n=40)包括临床、实验室和超声证实的任何原因的肝硬化;B组:(n=30)包括任何原因的慢性肝炎;C组(n=30)包括因胃肠道疾病就诊的非肝病患者。所有病例在分类前均进行了完整的病史和临床检查,全血计数、丙氨酸转氨酶、天冬氨酸转氨酶、血清白蛋白、凝血和血清胆红素、丙型肝炎病毒抗体(HCV Ab)和乙型肝炎表面抗原(HB Ag)、腹部超声检查、剪切波弹性成像SSM和上内镜诊断OV。结果在腹部超声和上腔镜检查方面,三组患者在脾脏、脾脏直径、SSM、腹水和OV方面差异有统计学意义(I组有腹水和OV的分别为27.5%和65%,而II组和III组无腹水和OV, P<0.001)。脾脏直径和SSM A组明显高于B、C组,但B、C组间差异不显著。OV分级A组ⅰ级5例,ⅱ级9例,ⅲ级5例,ⅳ级7例。OV分级与声辐射力冲击弹性图呈显著正相关(r=0.904, P <0.001)。结论剪切波弹性成像SSM是一种有效的无创参数,可用于肝硬化OV的检测和分级。
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引用次数: 0
Association between iron-deficiency anemia and febrile convulsion in children 儿童缺铁性贫血与热性惊厥的关系
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_207_20
S. Rashwan, Y. Ahmed, A. Ibrahim, Ismail Abd Kasem
Background and aim Previous studies reported that iron-deficiency could be a risk factor for febrile seizure (FS), as the latter is more common in children younger than 2 years, and iron-deficiency anemia is also common in children of the same age. Yet, the relationship between iron deficiency and FS is not yet determined, and that is why this study was suggested. The aim of this study was to assess the association between iron-deficiency anemia and febrile convulsion (FC). Patients and methods This study included 60 children aged 6 months to 5 years. These children were divided into three groups: a group of 20 patients with FC, a group of 20 patients with fever but without FC, and a group of 20 healthy children. Results The main findings of this study were that there was a higher incidence of FSs found among children who received formula feeding. Furthermore, children with FSs had the lowest level of hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, and transferrin saturation values. However, iron-deficiency anemia was not associated with increased incidence of FCs. Conclusion It can be concluded that formula feeding, low hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, and transferrin saturation are reinforcing factors for FSs.
背景和目的先前的研究报道,缺铁可能是热性惊厥(FS)的危险因素,因为后者在2岁以下儿童中更为常见,缺铁性贫血在同年龄儿童中也很常见。然而,缺铁和FS之间的关系尚未确定,这就是为什么提出这项研究的原因。本研究的目的是评估缺铁性贫血和热性惊厥(FC)之间的关系。患者和方法本研究包括60名6个月至5岁的儿童。这些儿童被分为三组:一组20名FC患者,一组20名发烧但没有FC的患者,一组20名健康儿童。结果本研究的主要发现是,配方奶喂养的儿童中FSs发生率较高。此外,FSs患儿的红细胞压积、平均红细胞体积、平均红细胞血红蛋白浓度和转铁蛋白饱和度均最低。然而,缺铁性贫血与fc发病率增加无关。结论配方喂养、低红细胞压积、平均红细胞体积、平均红细胞血红蛋白浓度和转铁蛋白饱和度是FSs的强化因素。
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引用次数: 0
Erratum: Sural and medial plantar nerve conduction study in the diagnosis of subclinical diabetic neuropathy 勘误:腓肠和内侧足底神经传导研究诊断亚临床糖尿病神经病变
Pub Date : 2022-01-01 DOI: 10.4103/1687-1693.348399
.
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引用次数: 0
Assessment of post-LASIK flap thickness created by mechanical microkeratomes by anterior segment optical coherence tomography 前段光学相干断层成像评价机械微角膜瓣lasik术后皮瓣厚度
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_116_21
Islam Amr, H. Yousef, A. Ahmed
Background and aim Laser-assisted in situ keratomileusis (LASIK) is the most popular refractive surgical operation for the correction of myopia, hyperopia, and astigmatism. Corneal flap creation is an essential step for the success of LASIK. The aim of the work is to evaluate the accuracy of the post-LASIK flap thickness created by mechanical microkeratomes using Anterior segment optical coherence tomography (ASOCT). Patients and methods This study included 60 eyes (of 30 patients), who underwent LASIK for refractive error correction. The patients were divided into two groups: (a) group A involved 30 eyes of 15 patients; in this group, the mechanical microkeratome Moria M2 (Moria M2, 110) was used. (b) Group B involved 30 eyes of 15 patients; in this group, the microkeratome Moria M2 (Moria M2, 100 with medlogic plano head) was used. Results As regards postoperative changes in flap thickness, the results of the current study showed that there were no considerable changes in thickness of the flap between 1 week, 1 month, 3 months, and 6 months postoperatively in either group. Conclusion Moria M2 100 with medlogic plano head created LASIK flaps with thinner thickness, and more predictability and more preservation of bed thickness than those created with the Moria M2 110.
背景与目的激光原位角膜磨镶术(LASIK)是目前最常用的矫正近视、远视和散光的屈光手术。角膜瓣的制作是LASIK手术成功的关键步骤。这项工作的目的是评估使用前段光学相干断层扫描(ASOCT)由机械微型角膜刀创建的LASIK术后皮瓣厚度的准确性。患者和方法本研究包括60眼(共30例),他们接受了LASIK屈光矫正术。将患者分为两组:(a)a组15例30眼;在该组中,使用机械显微角膜刀Moria M2(Moria M2110)。(b) b组15例30眼;本组采用Moria M2微型角膜刀(Moria M2100,带混合性平头)。结果关于皮瓣厚度的术后变化,本研究结果显示,两组在术后1周、1个月、3个月和6个月内皮瓣厚度均无明显变化。结论Moria M2 100与Moria M2 110相比,可制作厚度更薄、可预测性更强、床层厚度保留率更高的LASIK皮瓣。
{"title":"Assessment of post-LASIK flap thickness created by mechanical microkeratomes by anterior segment optical coherence tomography","authors":"Islam Amr, H. Yousef, A. Ahmed","doi":"10.4103/azmj.azmj_116_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_116_21","url":null,"abstract":"Background and aim Laser-assisted in situ keratomileusis (LASIK) is the most popular refractive surgical operation for the correction of myopia, hyperopia, and astigmatism. Corneal flap creation is an essential step for the success of LASIK. The aim of the work is to evaluate the accuracy of the post-LASIK flap thickness created by mechanical microkeratomes using Anterior segment optical coherence tomography (ASOCT). Patients and methods This study included 60 eyes (of 30 patients), who underwent LASIK for refractive error correction. The patients were divided into two groups: (a) group A involved 30 eyes of 15 patients; in this group, the mechanical microkeratome Moria M2 (Moria M2, 110) was used. (b) Group B involved 30 eyes of 15 patients; in this group, the microkeratome Moria M2 (Moria M2, 100 with medlogic plano head) was used. Results As regards postoperative changes in flap thickness, the results of the current study showed that there were no considerable changes in thickness of the flap between 1 week, 1 month, 3 months, and 6 months postoperatively in either group. Conclusion Moria M2 100 with medlogic plano head created LASIK flaps with thinner thickness, and more predictability and more preservation of bed thickness than those created with the Moria M2 110.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"104 - 112"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47992964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Audiovestibular performance in patients with low bone mineral density: a case–control study 低骨密度患者的听前庭功能:一项病例对照研究
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_119_21
M. Elwan, M. Elmoursy, Ahmed Ibrahim Metwaly, M. Ryan
Background and aim Audiovestibular dysfunctions have been previously linked to osteoporosis (OP) with controversies about the mutual relationship. In this study, we aimed to assess the audiovestibular functions in patients with OP and osteopenia and to study their association with vitamin D deficiency. Patients and methods Of 60 patients enrolled in this study, 30 had low bone mineral density (BMD) (group I) and 30 had normal BMD (group II). After clinical examination and evaluation of serum vitamin D and calcium levels, the participants then were referred for audiovestibular assessments, which included basic audiological evaluation by pure tone audiometry and speech audiometry, tympanometry, acoustic reflex, video-nystagmoscopy tests, and vestibular-evoked myogenic potential (VEMP) to assess saccular function. Both participants and audiologist were blinded regarding the BMD results. Results There was a significant difference between patients and controls regarding the level of calcium (P=0.002) and vitamin D (P=0.001). There was a significant difference in the normal hearing threshold between both groups (P=0.005). There was no significant difference in VEMP testing (VEMP P1; P=0.489, amplitude; P=0.898). Benign paroxysmal positional vertigo was the most common finding in group I, among the females, where they had vitamin D deficiency (16.67±4.16) and OP (mean T score=−2.73±0.06). Conclusions Patients with low BMD showed a greater degree of audiovestibular dysfunction, which should be considered among the associating risk factors and comorbidities. Assessment of the audiovestibular functions should be recommended for patients with low BMD in the management guidelines.
背景和目的听前庭功能障碍以前曾与骨质疏松症(OP)有关,但对其相互关系存在争议。在这项研究中,我们旨在评估OP和骨质减少患者的听前庭功能,并研究它们与维生素D缺乏的关系。患者和方法在本研究的60名患者中,30名患者的骨密度较低(I组),30名骨密度正常(II组)。在临床检查和评估血清维生素D和钙水平后,参与者被转诊进行听前庭评估,包括通过纯音测听和言语测听进行的基本听力学评估、鼓室测量、声反射、视频眼球震颤测试和前庭诱发肌源电位(VEMP)来评估囊状功能。参与者和听力学家都对BMD结果视而不见。结果患者和对照组在钙(P=0.002)和维生素D(P=0.001)水平上有显著差异。两组的正常听阈有显著差异(P=0.005)。VEMP测试无显著差异(VEMP P1;P=0.489,振幅;P=0.898)I组,女性,维生素D缺乏(16.67±4.16)和OP(平均T分=-2.73±0.06)。结论低BMD患者表现出更大程度的听前庭功能障碍,应将其作为相关的危险因素和合并症之一。管理指南中应建议低骨密度患者进行听前庭功能评估。
{"title":"Audiovestibular performance in patients with low bone mineral density: a case–control study","authors":"M. Elwan, M. Elmoursy, Ahmed Ibrahim Metwaly, M. Ryan","doi":"10.4103/azmj.azmj_119_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_119_21","url":null,"abstract":"Background and aim Audiovestibular dysfunctions have been previously linked to osteoporosis (OP) with controversies about the mutual relationship. In this study, we aimed to assess the audiovestibular functions in patients with OP and osteopenia and to study their association with vitamin D deficiency. Patients and methods Of 60 patients enrolled in this study, 30 had low bone mineral density (BMD) (group I) and 30 had normal BMD (group II). After clinical examination and evaluation of serum vitamin D and calcium levels, the participants then were referred for audiovestibular assessments, which included basic audiological evaluation by pure tone audiometry and speech audiometry, tympanometry, acoustic reflex, video-nystagmoscopy tests, and vestibular-evoked myogenic potential (VEMP) to assess saccular function. Both participants and audiologist were blinded regarding the BMD results. Results There was a significant difference between patients and controls regarding the level of calcium (P=0.002) and vitamin D (P=0.001). There was a significant difference in the normal hearing threshold between both groups (P=0.005). There was no significant difference in VEMP testing (VEMP P1; P=0.489, amplitude; P=0.898). Benign paroxysmal positional vertigo was the most common finding in group I, among the females, where they had vitamin D deficiency (16.67±4.16) and OP (mean T score=−2.73±0.06). Conclusions Patients with low BMD showed a greater degree of audiovestibular dysfunction, which should be considered among the associating risk factors and comorbidities. Assessment of the audiovestibular functions should be recommended for patients with low BMD in the management guidelines.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"121 - 126"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49153353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between central corneal thickness and axial eye length using partial coherence interferometry 用部分相干干涉法测定角膜中央厚度与眼轴长度的关系
Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_139_21
Wafaa Abdelkhalek, H. Hegazy, Mohamed I. EL-Kasaby
Background and aim Several studies have shown the relationship between axial length (AL) of the eye and central corneal thickness (CCT). Since genetics, ethnicity, and race can affect these factors, their differences between different societies can probably explain refractive error variance. We present the ocular parameter values in 154 eyes of different refractive error groups to investigate the correlation between AL of the eye and CCT in Egyptians with refractive errors. Patients and methods In all, 154 patients were classified into emmetropic, hypermetropic, simple myopic, congenital myopic, and malignant myopic groups. Most ocular parameters were achieved using IOLMaster 700 and stratified according to AL and CCT. Results The CCT means in the studied groups was 537±34, 523±31, 541±40, 524±40, and 524±27 μm in emmetropic, hypermetropic, simple myopic, congenital myopic, and malignant myopic groups, respectively. The AL was 23±0.76, 22±1.1, 25±1.3, 26±1.4, and 29±1.6 mm, respectively. Regarding the correlation between AL of the eye and CCT (r=−0.01, P=0.92, confidence interval=−0.17 to 0.15). Conclusion This study provided valued measurements of ocular parameters of the Egyptians with refractive errors. Besides, there is no significant correlation between AL of the eye and its CCT in Egyptians with errors of refraction.
背景与目的已有多项研究表明眼轴长(AL)与角膜中央厚度(CCT)之间存在相关性。由于遗传、种族和种族可以影响这些因素,不同社会之间的差异可能可以解释屈光不正的差异。我们提供了不同屈光不正组的154只眼睛的眼部参数值,以研究屈光不正埃及人眼睛AL与CCT的相关性。患者与方法将154例患者分为准远视、远视、单纯性近视、先天性近视和恶性近视组。使用IOLMaster 700获得大多数眼部参数,并根据AL和CCT进行分层。结果远视组、远视组、单纯性近视组、先天性近视组、恶性近视组CCT均值分别为537±34、523±31、541±40、524±40、524±27 μm。AL分别为23±0.76、22±1.1、25±1.3、26±1.4、29±1.6 mm。眼AL与CCT的相关性(r= - 0.01, P=0.92,置信区间= - 0.17 ~ 0.15)。结论本研究为埃及屈光不正患者提供了有价值的眼参数测量方法。此外,埃及人的眼睛AL与屈光不正的CCT之间没有显著的相关性。
{"title":"Relationship between central corneal thickness and axial eye length using partial coherence interferometry","authors":"Wafaa Abdelkhalek, H. Hegazy, Mohamed I. EL-Kasaby","doi":"10.4103/azmj.azmj_139_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_139_21","url":null,"abstract":"Background and aim Several studies have shown the relationship between axial length (AL) of the eye and central corneal thickness (CCT). Since genetics, ethnicity, and race can affect these factors, their differences between different societies can probably explain refractive error variance. We present the ocular parameter values in 154 eyes of different refractive error groups to investigate the correlation between AL of the eye and CCT in Egyptians with refractive errors. Patients and methods In all, 154 patients were classified into emmetropic, hypermetropic, simple myopic, congenital myopic, and malignant myopic groups. Most ocular parameters were achieved using IOLMaster 700 and stratified according to AL and CCT. Results The CCT means in the studied groups was 537±34, 523±31, 541±40, 524±40, and 524±27 μm in emmetropic, hypermetropic, simple myopic, congenital myopic, and malignant myopic groups, respectively. The AL was 23±0.76, 22±1.1, 25±1.3, 26±1.4, and 29±1.6 mm, respectively. Regarding the correlation between AL of the eye and CCT (r=−0.01, P=0.92, confidence interval=−0.17 to 0.15). Conclusion This study provided valued measurements of ocular parameters of the Egyptians with refractive errors. Besides, there is no significant correlation between AL of the eye and its CCT in Egyptians with errors of refraction.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"148 - 153"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46482241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Estimation of vitamin D level in type 1 diabetic children 1型糖尿病儿童维生素D水平的评估
Pub Date : 2021-10-01 DOI: 10.4103/AZMJ.AZMJ_111_20
Enas Ahmed Hassan, Y. Ahmed, M. Hassan, M. Bashir
Background and Aim Previous studies have shown the relationship between children with type 1 diabetes and vitamin D. To evaluate the level of vitamin D in children with type 1 diabetes and the effect of low vitamin D level on the long-term blood glucose controls reflected by glycated hemoglobin. Patients and methods The study included 20 children who had already been diagnosed as having type 1 diabetes mellitus with vitamin D deficiency and 20 normal nondiabetic children as a control group. Full history taking, clinical examinations, and investigations for all children, including serum 25-hydroxy vitamin D level, were done. Results Vitamin D deficiency was present in ∼85% of children with type 1 diabetes compared with nondiabetic control, who showed good vitamin D level. Conclusion Type 1 diabetic children are associated with low vitamin D level. Perhaps infants supplemented with vitamin D level might be a safe and effective plan for decreasing the risk of type 1 diabetes and also may decrease and improve levels of glucose and glycated hemoglobin levels in type 1 diabetes mellitus.
背景与目的已有研究表明1型糖尿病儿童与维生素D之间存在相关性。评价1型糖尿病儿童维生素D水平及低维生素D水平对糖化血红蛋白反映的长期血糖控制的影响。研究对象包括20名已确诊为1型糖尿病合并维生素D缺乏症的儿童和20名正常的非糖尿病儿童作为对照组。对所有儿童进行完整的病史记录、临床检查和调查,包括血清25-羟基维生素D水平。结果与维生素D水平良好的非糖尿病对照组相比,约85%的1型糖尿病儿童存在维生素D缺乏症。结论1型糖尿病患儿维生素D水平低。也许婴儿补充维生素D水平可能是一种安全有效的降低1型糖尿病风险的计划,也可能降低和改善1型糖尿病患者的葡萄糖和糖化血红蛋白水平。
{"title":"Estimation of vitamin D level in type 1 diabetic children","authors":"Enas Ahmed Hassan, Y. Ahmed, M. Hassan, M. Bashir","doi":"10.4103/AZMJ.AZMJ_111_20","DOIUrl":"https://doi.org/10.4103/AZMJ.AZMJ_111_20","url":null,"abstract":"Background and Aim Previous studies have shown the relationship between children with type 1 diabetes and vitamin D. To evaluate the level of vitamin D in children with type 1 diabetes and the effect of low vitamin D level on the long-term blood glucose controls reflected by glycated hemoglobin. Patients and methods The study included 20 children who had already been diagnosed as having type 1 diabetes mellitus with vitamin D deficiency and 20 normal nondiabetic children as a control group. Full history taking, clinical examinations, and investigations for all children, including serum 25-hydroxy vitamin D level, were done. Results Vitamin D deficiency was present in ∼85% of children with type 1 diabetes compared with nondiabetic control, who showed good vitamin D level. Conclusion Type 1 diabetic children are associated with low vitamin D level. Perhaps infants supplemented with vitamin D level might be a safe and effective plan for decreasing the risk of type 1 diabetes and also may decrease and improve levels of glucose and glycated hemoglobin levels in type 1 diabetes mellitus.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"19 1","pages":"564 - 568"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43609402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study between intramyometrial oxytocin and oxytocin analogue (carbetocin) in prevention of postpartum hemorrhage following cesarean section 子宫内膜内催产素与催产素类似物卡贝菌素预防剖宫产术后产后出血的比较研究
Pub Date : 2021-10-01 DOI: 10.4103/AZMJ.AZMJ_126_20
F. Kassab, A. Sedek
Background and aim This is a prospective randomized single-center study aimed to assess the efficacy of carbetocin versus intramyometrial oxytocin in the prevention of atonic postpartum hemorrhage following Cesarean section in high-risk women. Patients and methods A total of 160 women with gestational age more than 38 weeks at high risk for primary atonic postpartum hemorrhage undergoing elective or urgent cesarean section under regional or general anesthesia were randomly divided into two equal groups: group A included 80 patients, and they received oxytocin 20 IU intramyometrially. Group B included 80 patients, and they received carbetocin, 100 μg intravenously. Results There was no significant difference in the mean values of hematocrit before and 24 h after delivery (P>0.05). Similarly, there was no significant difference in the estimated blood loss calculated by hematocrit values (P>0.05). Moreover, it was shown that 17.5% of women in the carbetocin group needed additional uterotonics versus 25% of women in the oxytocin group. Therefore, there was no significant difference between both groups regarding needing additional uterotonics. There were eight cases that needed more surgical intervention. Conclusion Both drugs are equally effective in prevention of atonic postpartum hemorrhage. There is no significant difference between single injection of carbetocin and intramyometrial 20 IU oxytocin in reducing the use of additional oxytocic agents.
背景和目的这是一项前瞻性随机单中心研究,旨在评估卡贝托星与子宫内催产素在高危女性剖宫产后预防无张力产后出血方面的疗效。患者和方法160例孕龄38周以上原发性无张力产后出血高危妇女在区域或全身麻醉下接受选择性或紧急剖宫产手术,随机分为两组:A组80例,子宫内注射催产素20IU。B组包括80名患者,他们接受了卡贝托星治疗 μg静脉注射。结果术前和术后24小时红细胞压积平均值无显著性差异 同样,通过红细胞压积值计算的估计失血量也没有显著差异(P>0.05)。此外,研究表明,卡贝托星组17.5%的女性需要额外的子宫补剂,而催产素组为25%。因此,两组在需要额外的子宫补剂方面没有显著差异。有8个病例需要更多的手术干预。结论两种药物预防无张力产后出血效果相同。单次注射卡贝托星和子宫内膜注射20 IU催产素在减少额外催产素使用方面没有显著差异。
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引用次数: 0
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Al-Azhar Assiut Medical Journal
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