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THE EFFECT OF BIOCOMPOSITE GRAFTING MATERIAL ON CALVARIAL BONE REGENERATION (AN EXPERIMENTAL STUDY) 生物复合移植材料对腓骨再生的影响(实验研究)
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.148596.1295
Muoaaid Alabd althiab, Mahitab Soliman, Lydia F. Melek, Hagar Abdel Fattah
INTRODUCTION: regenerating bone deficiencies produced by trauma or periodontal disorder is a major objective. The surgeon constantly seeks to collect enough bone to finish his tasks as well as to replace the amount of bone that has been lost. In oral surgery, bone grafting is a method frequently employed to make up for lost hard tissue. AIM OF THE STUDY: comparing the bone healing rate of critical defect sizes in the calvaria rabbit with and without using a bio-composite material, both histopathologically and histomorphometrically. MATERIALS AND METHODS: Two bone deficiencies were prepared on the Rabbits’ calvaria of. The right-handed defect was the control and the left-handed defect was the study group in all of the rabbits. The control had the defect left without anything, while the study group was received biocomposite material (bone collagen, bone sulfated glycosaminoglycans sulphated glucosamine glycans (sGAG) and hydroxyapatite in natural form). At 2, 4, 6 weeks intervals, the animals were euthanized. RESULTS: The histopathological and histomorphometric results revealed a new bone formation in both groups, the study group showed enhanced quality and quantity. CONCLUSION: The current histological and histomorphological investigation of rabbit cranial bone deficiencies after treating with the test resorbable alloplastic graft showed an excellent biocompatibility of both the biomaterial and the distinct newly formed bone after a 6 weeks period of healing.
由创伤或牙周疾病产生的骨缺损再生是一个主要目标。外科医生不断地收集足够的骨头来完成手术,并补充丢失的骨头。在口腔外科中,植骨是一种常用的方法来弥补丢失的硬组织。研究的目的:比较使用和不使用生物复合材料的兔颅骨关键缺损的骨愈合率,包括组织病理学和组织形态计量学。材料与方法:在兔颅骨上制备两种骨缺损。所有家兔右撇子缺陷为对照组,左撇子缺陷为研究组。对照组不保留缺损,研究组采用生物复合材料(骨胶原蛋白、骨硫酸氨基糖聚糖(sGAG)和天然羟基磷灰石)。每隔2、4、6周对这些动物实施安乐死。结果:两组组织病理学和组织形态学结果均显示新生骨形成,研究组骨质量和数量均有所提高。结论:目前对兔颅骨缺损的组织学和组织形态学研究表明,在6周的愈合期后,生物材料和独特的新生骨均具有良好的生物相容性。
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引用次数: 0
REMINERALIZATION OF SELF-ASSEMBLING PEPTIDE P11-4 AND CASEIN PHOSPHOPEPTIDE-AMORPHOUS CALCIUM PHOSPHATE FLUORIDE ON CARIES-LIKE LESIONS IN PRIMARY TEETH (IN-VITRO STUDY) 自组装肽 p11-4 和酪蛋白磷酸肽-无定形磷酸钙氟化物对乳牙龋齿样病变的再矿化作用(体外研究)
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2023.246496.1432
Peter Habashy, K. Dowidar, hager Abdel Fattah, Dina Sharaf
INTRODUCTION: The early stages of dental caries involve enamel demineralization which can be reversed. Attempts have been made to develop new materials to remineralize enamel. OBJECTIVES: To assess remineralizing effect of Self-assembling Peptide P11-4 and Casein Phosphopeptide-Amorphous Calcium Phosphate Fluoride (CPP-ACPF) in comparison to Sodium Fluoride varnish on early carious lesions in primary teeth. MATERIALS AND METHODS: Thirty-six sound-extracted primary anterior teeth were used. A 4x4mm window was made in the middle of the labial surface of each tooth. Teeth were subjected to artificial demineralization and then randomly allocated into 3 groups: Group I(5%NaF varnish), Group II(CPP-ACPF varnish) and Group III(P11-4). Teeth were sectioned longitudinally into two halves. One half was treated by the remineralizing agent, and the other was left untreated as a negative control. Samples were subjected to elemental analysis using Energy Dispersive X-ray spectrometer(EDX) where the Calcium and phosphorus contents were estimated and the surface topography was assessed by Scanning-Electron-Microscope(SEM). Comparison of Calcium/Phosphorus ratio was done using One Way ANOVA and the differences in percent change were analyzed using the Kruskal Wallis test. RESULTS: There was a significant difference in the mineral content within each group before and after treatment indicating remineralization in all groups. The percent increase in Ca/P ratio after treatment was higher in P11-4 group with no significant difference between groups. Surface topography showed improvement in all groups with better surface quality in self-assembling peptide P11-4 group than other groups. CONCLUSION: The CPP-ACPF varnish, Self-assembling peptide P11-4 and 5% Sodium fluoride varnish are effective in restoring the mineral content and improving surface morphology of early carious lesions in primary teeth.
简介:龋齿的早期阶段包括牙釉质脱矿,这是可以逆转的。人们曾尝试开发新的材料使牙釉质再矿化。目的:比较自组装肽P11-4和酪蛋白磷酸肽-无定形氟化磷酸钙(CPP-ACPF)与氟化钠清漆对乳牙早期龋齿的再矿化作用。材料与方法:使用36颗超声拔牙的初级前牙。在每颗牙齿的唇面中间做一个4x4mm的窗口。牙体进行人工脱矿,随机分为3组:1组(5%NaF清漆)、2组(pcp - acpf清漆)、3组(P11-4)。牙齿纵切成两半。其中一半用再矿化剂治疗,另一半不治疗作为阴性对照。利用能量色散x射线光谱仪(EDX)对样品进行元素分析,并通过扫描电子显微镜(SEM)对样品的表面形貌进行了分析。钙磷比比较采用单因素方差分析,百分比变化差异采用Kruskal Wallis检验分析。结果:治疗前后各组患者体内矿物质含量差异有统计学意义,说明各组均存在再矿化现象。P11-4组治疗后Ca/P比值升高百分比较高,组间差异无统计学意义。各组表面形貌均有改善,自组装肽P11-4组表面质量较其他组好。结论:CPP-ACPF清漆、自组装肽P11-4和5%氟化钠清漆能有效恢复乳牙早期龋损的矿物质含量,改善表面形态。
{"title":"REMINERALIZATION OF SELF-ASSEMBLING PEPTIDE P11-4 AND CASEIN PHOSPHOPEPTIDE-AMORPHOUS CALCIUM PHOSPHATE FLUORIDE ON CARIES-LIKE LESIONS IN PRIMARY TEETH (IN-VITRO STUDY)","authors":"Peter Habashy, K. Dowidar, hager Abdel Fattah, Dina Sharaf","doi":"10.21608/adjalexu.2023.246496.1432","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.246496.1432","url":null,"abstract":"INTRODUCTION: The early stages of dental caries involve enamel demineralization which can be reversed. Attempts have been made to develop new materials to remineralize enamel. OBJECTIVES: To assess remineralizing effect of Self-assembling Peptide P11-4 and Casein Phosphopeptide-Amorphous Calcium Phosphate Fluoride (CPP-ACPF) in comparison to Sodium Fluoride varnish on early carious lesions in primary teeth. MATERIALS AND METHODS: Thirty-six sound-extracted primary anterior teeth were used. A 4x4mm window was made in the middle of the labial surface of each tooth. Teeth were subjected to artificial demineralization and then randomly allocated into 3 groups: Group I(5%NaF varnish), Group II(CPP-ACPF varnish) and Group III(P11-4). Teeth were sectioned longitudinally into two halves. One half was treated by the remineralizing agent, and the other was left untreated as a negative control. Samples were subjected to elemental analysis using Energy Dispersive X-ray spectrometer(EDX) where the Calcium and phosphorus contents were estimated and the surface topography was assessed by Scanning-Electron-Microscope(SEM). Comparison of Calcium/Phosphorus ratio was done using One Way ANOVA and the differences in percent change were analyzed using the Kruskal Wallis test. RESULTS: There was a significant difference in the mineral content within each group before and after treatment indicating remineralization in all groups. The percent increase in Ca/P ratio after treatment was higher in P11-4 group with no significant difference between groups. Surface topography showed improvement in all groups with better surface quality in self-assembling peptide P11-4 group than other groups. CONCLUSION: The CPP-ACPF varnish, Self-assembling peptide P11-4 and 5% Sodium fluoride varnish are effective in restoring the mineral content and improving surface morphology of early carious lesions in primary teeth.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ADAPTATION AND PENETRATION OF THREE DIFFERENT ROOT CANAL SEALERS WITH SINGLE CONE OBTURATION TECHNIQUE: A SCANNING ELECTRON MICROSCOPE STUDY (AN IN VITRO STUDY) 三种不同根管封闭剂与单锥封堵技术的适应性和渗透性:扫描电子显微镜研究(体外研究)
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.151014.1298
Ahmad Abdeen, Raef A. Sherif, Mahmoud Aboelseoud
INTRODUCTION: Obturation materialswith superior adaptation and sealing capacity are crucial for root canal treatment success. OBJECTIVE: To compare adaptation and tubular penetration depth of three different sealers (Ceraseal, AH Plus and Endofill)with single cone obturation technique using scanning electron microscope (SEM). MATERIALS AND METHODS: Thirty-six extracted single canaled mandibular premolar teeth were decoronated and prepared using ProTaper Universal rotary files till F3. Teeth were randomly divided into three groups according to sealer type used: Group I: Ceraseal (Bioceramic), Group II: AH Plus (Resin), Group III: Endofill (Zinc Oxide Eugenol). All roots were obturated with a single F3 cone with one of the assigned sealers. Teeth were sectioned into threethirds horizontally and analyzed for sealer adaptation and penetration using SEM. RESULTS: Regarding sealer adaptation,roots filled with AH Plus showed better adaptation (less mean gap sizes) than other sealers in the three canal thirdsand the least mean gap sizes were recorded in the apical third in all groups. Along the complete canal length,a significant difference was found between AH Plus group and other groups (P <0.0001).Regarding tubular penetration depth, Ceraseal showed greater mean penetration depth in the middle and apical thirds than other sealers. However, along complete canal length, no significant difference was found between Ceraseal and AH Plus groupswith a significant difference noted between both groups and Endofillgroup (P <0.0001). CONCLUSION: Single cone obturation with AH Plus and Ceraseal could result in significant better adaptation and tubular penetration than Endofill sealer.
具有良好适应性和密封能力的充填材料是根管治疗成功的关键。目的:应用扫描电镜(SEM)比较三种不同封堵剂(Ceraseal、AH Plus和Endofill)在单锥封堵技术下的适应性和管状渗透深度。材料与方法:采用ProTaper万能旋转锉对36颗拔除的单根管下颌前磨牙进行整复,直至F3。根据使用的封口剂类型随机分为3组:I组:Ceraseal(生物陶瓷),II组:AH Plus(树脂),III组:Endofill(氧化锌丁香酚)。所有的根都用一个F3锥体封闭,其中一个指定的封闭器。将牙齿水平切成三分之二,用扫描电镜分析密封剂的适应性和穿透性。结果:在对封闭物的适应方面,经AH +充填的根在三根管三分之一处表现出较好的适应能力(平均间隙大小较小),且各组根尖三分之一处的平均间隙大小最小。在全根管长度上,AH +组与其他组差异有统计学意义(P <0.0001)。在管状穿透深度方面,Ceraseal在中间和根尖三分之一处的平均穿透深度大于其他密封剂。然而,沿着全管长度,Ceraseal组和AH Plus组之间无显著差异,两组与Endofillgroup组之间有显著差异(P <0.0001)。结论:与Endofill密封剂相比,AH Plus和Ceraseal的单锥封闭剂具有更好的适应性和管状穿透性。
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引用次数: 0
ASSESSMENT OF THREE HEAT TREATED SINGLE FILE SYSTEMS IN GUTTA-PERCHA REMOVAL USING CONE BEAM COMPUTED TOMOGRAPHY (AN IN VITRO STUDY) 使用锥形束计算机断层扫描评估三种热处理单锉系统在去除牙胶方面的效果(体外研究)
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.144389.1291
Mohamed Elnagar, Ahmed Mobarak, Amr Abdallah
INTRODUCTION: Absolute removal of the defective root filling material and regaining apical patency is the primary factor of endodontic retreatment success. AIM OF THE STUDY: Assessment of the ability of Reciproc R25 (VDW, Munich, Germany), Reciproc blue (VDW, Munich, Germany) and the XP-endo shaper (FKG Dentaire, La Chaux-de-Fonds, Switzerland) thermally treated rotary files in removing of the root filling material from oval shaped canals using cone beam computed tomography (CBCT). MATERIALS AND METHODS: Thirty six extracted single canaled human mandibular premolar teeth were prepared chemo-mechanically using Revo-S rotary file system (Micro-Mega, France) and obturated. The teeth were randomly allocated into three groups (n=12 each) depending on files used in retreatment procedure as follow: Group I: Reciproc R25, Group II: Reciproc blue, Group III: XP-endo shaper. Pre and post retreatment scans were done using CBCT to calculate the volume of the remaining gutta percha by using computer software (Osirix lite). Time consumed by each file was recoded until gutta percha was completely removed. RESULTS: All used files were not able to remove the entire root filling material from the canals. No statistically significant differences (P> 0.05) in residual gutta percha were detected between the groups, the percentage of reduction was 88.87 % in (Group Ⅰ ), 92.22 % in (Group Ⅱ ), and 88.60 % in (Group Ⅲ ). The XP-endo shaper required more time with statistically significant difference than the Reciproc groups in gutta percha removal. CONCLUSION: All systems removed the root filling material from oval shaped canals effectively. Both reciproc systems were faster than XP-endo shaper in gutta percha removal.
完全清除缺损的根管充填材料,恢复根尖通畅是根管再治疗成功的首要因素。研究目的:评估Reciproc R25 (VDW,慕尼黑,德国)、Reciproc blue (VDW,慕尼黑,德国)和XP-endo shaper (FKG Dentaire, La Chaux-de-Fonds,瑞士)热处理旋转锉在锥形束计算机断层扫描(CBCT)中去除椭圆形根管充填材料的能力。材料与方法:采用Revo-S旋转文件系统(Micro-Mega, France)化学机械法制备36颗拔除的人下颌前磨牙,并进行封闭。根据再治疗过程中使用的锉刀,将牙随机分为3组,每组12颗:I组:Reciproc R25, II组:Reciproc blue, III组:XP-endo shaper。再治疗前后采用CBCT扫描,利用计算机软件(Osirix lite)计算剩余杜胶的体积。每个文件所消耗的时间被重新编码,直到杜胶被完全删除。结果:所有使用的锉都不能将根管充填材料全部从根管中取出。各组间杜胶残留量差异无统计学意义(P> 0.05),分别为88.87%(Ⅰ组)、92.22%(Ⅱ组)和88.60%(Ⅲ组)。与Reciproc组相比,XP-endo塑形器组需要更多的时间去除杜仲胶,差异有统计学意义。结论:所有系统均能有效去除椭圆根管中的根充填物。这两种系统在去除杜仲胶方面都比XP-endo塑形器快。
{"title":"ASSESSMENT OF THREE HEAT TREATED SINGLE FILE SYSTEMS IN GUTTA-PERCHA REMOVAL USING CONE BEAM COMPUTED TOMOGRAPHY (AN IN VITRO STUDY)","authors":"Mohamed Elnagar, Ahmed Mobarak, Amr Abdallah","doi":"10.21608/adjalexu.2022.144389.1291","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.144389.1291","url":null,"abstract":"INTRODUCTION: Absolute removal of the defective root filling material and regaining apical patency is the primary factor of endodontic retreatment success. AIM OF THE STUDY: Assessment of the ability of Reciproc R25 (VDW, Munich, Germany), Reciproc blue (VDW, Munich, Germany) and the XP-endo shaper (FKG Dentaire, La Chaux-de-Fonds, Switzerland) thermally treated rotary files in removing of the root filling material from oval shaped canals using cone beam computed tomography (CBCT). MATERIALS AND METHODS: Thirty six extracted single canaled human mandibular premolar teeth were prepared chemo-mechanically using Revo-S rotary file system (Micro-Mega, France) and obturated. The teeth were randomly allocated into three groups (n=12 each) depending on files used in retreatment procedure as follow: Group I: Reciproc R25, Group II: Reciproc blue, Group III: XP-endo shaper. Pre and post retreatment scans were done using CBCT to calculate the volume of the remaining gutta percha by using computer software (Osirix lite). Time consumed by each file was recoded until gutta percha was completely removed. RESULTS: All used files were not able to remove the entire root filling material from the canals. No statistically significant differences (P> 0.05) in residual gutta percha were detected between the groups, the percentage of reduction was 88.87 % in (Group Ⅰ ), 92.22 % in (Group Ⅱ ), and 88.60 % in (Group Ⅲ ). The XP-endo shaper required more time with statistically significant difference than the Reciproc groups in gutta percha removal. CONCLUSION: All systems removed the root filling material from oval shaped canals effectively. Both reciproc systems were faster than XP-endo shaper in gutta percha removal.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138612317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF THE SHAPING ABILITY OF EDGEFILE X-7, XP-ENDO SHAPER AND TRUNATOMY ROTARY FILES IN MESIOBUCCAL CANALS OF LOWER MANDIBULAR MOLARS USING CONE BEAM COMPUTED TOMOGRAPHY (IN-VITRO STUDY) 使用锥形束计算机断层扫描评估 Edgefile X-7、XP-endo 成型器和 Trunatomy 旋转锉在下颌磨牙中颊面管中的成型能力(体外研究)
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.147077.1293
moustafa bakr, Ahmed Mobarak, Amr Abdallah
INTRODUCTION: The main aim of mechanical instrumentation during root canal treatment is to remove the inner layer of dentin to facilitate removing of all bacteria and smear layer from the canal. New rotary files designs allow more contact to canal walls to improve canal cleaning and shaping. AIM OF STUDY: The goal of this study was to assess the shaping ability of EdgeFile X-7, XP-endo shaper and TruNatomy rotary files in mesiobuccal root canals of mandibular molars using cone beam computed tomography (CBCT). METHODS: Thirty unidentified extracted roots of human mandibular molar teeth of mild root curvature were selected for this study. Chemo-mechanically preparation of all the teeth were done using three different nickel titanium (Ni-Ti) rotary file systems. The teeth were divided randomly into three groups (n=10 each) according to the rotary files used in preparation procedure as follows: Group I: EdgeFile X-7, Group II: XP-endo shaper, Group III: TruNatomy. The incidence of canal transportation and centering ability by these rotary files’ instrumentation were assessed using CBCT pre and post scanning. RESULTS: Variation in canal transportation and centering ability between groups were compared using Kruskal Wallis test and Freidman test at three mm, six mm, and nine mm levels within all groups. Significance level was set at P value equal 0.05. Showing no significance difference between the three rotary files including centering ability and canal transportation. CONCLUSION: All the three rotary systems were proved to prepare root canals with low canal transportation and good centering ability.
简介:在根管治疗过程中,机械器械的主要目的是去除牙本质的内层,以便清除根管上的所有细菌和涂片层。新的旋转锉设计允许更多地接触管壁,以改善管的清洁和成型。研究目的:本研究的目的是利用锥形束计算机断层扫描(CBCT)评估EdgeFile X-7、XP-endo塑形器和TruNatomy旋转锉在下颌磨牙中颊根管中的塑形能力。方法:选取30例下颌磨牙根曲轻微的未鉴别拔牙根进行研究。使用三种不同的镍钛(Ni-Ti)旋转锉系统对所有牙齿进行化学机械制备。根据预备过程中使用的旋转锉随机分为三组(每组10颗):第一组:EdgeFile X-7,第二组:XP-endo shaper,第三组:TruNatomy。通过CBCT前后扫描评估这些旋转锉器械对根管运输的发生率和对中能力。结果:采用Kruskal Wallis检验和Freidman检验比较各组在3 mm、6 mm和9 mm水平上的运河运输和定心能力的差异。P值为0.05。三种旋转锉在定心能力和运河运输方面无显著性差异。结论:三种旋转系统均可制备根管,根管运输量低,对中能力好。
{"title":"EVALUATION OF THE SHAPING ABILITY OF EDGEFILE X-7, XP-ENDO SHAPER AND TRUNATOMY ROTARY FILES IN MESIOBUCCAL CANALS OF LOWER MANDIBULAR MOLARS USING CONE BEAM COMPUTED TOMOGRAPHY (IN-VITRO STUDY)","authors":"moustafa bakr, Ahmed Mobarak, Amr Abdallah","doi":"10.21608/adjalexu.2022.147077.1293","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.147077.1293","url":null,"abstract":"INTRODUCTION: The main aim of mechanical instrumentation during root canal treatment is to remove the inner layer of dentin to facilitate removing of all bacteria and smear layer from the canal. New rotary files designs allow more contact to canal walls to improve canal cleaning and shaping. AIM OF STUDY: The goal of this study was to assess the shaping ability of EdgeFile X-7, XP-endo shaper and TruNatomy rotary files in mesiobuccal root canals of mandibular molars using cone beam computed tomography (CBCT). METHODS: Thirty unidentified extracted roots of human mandibular molar teeth of mild root curvature were selected for this study. Chemo-mechanically preparation of all the teeth were done using three different nickel titanium (Ni-Ti) rotary file systems. The teeth were divided randomly into three groups (n=10 each) according to the rotary files used in preparation procedure as follows: Group I: EdgeFile X-7, Group II: XP-endo shaper, Group III: TruNatomy. The incidence of canal transportation and centering ability by these rotary files’ instrumentation were assessed using CBCT pre and post scanning. RESULTS: Variation in canal transportation and centering ability between groups were compared using Kruskal Wallis test and Freidman test at three mm, six mm, and nine mm levels within all groups. Significance level was set at P value equal 0.05. Showing no significance difference between the three rotary files including centering ability and canal transportation. CONCLUSION: All the three rotary systems were proved to prepare root canals with low canal transportation and good centering ability.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138612720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INTRALESIONAL INJECTION OF ETHANOLAMINE OLEATE WITH OR WITHOUT LOCAL ANAESTHETIC AGENT TO ASSESS POSTOPERATIVE PAIN IN ORAL VENOUS MALFORMATIONS (A RANDOMIZED CONTROLLED CLINICAL TRIAL) 口腔静脉畸形术后疼痛评估(随机对照临床试验):油酸乙醇胺(含或不含局部麻醉剂)的穴内注射
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.167165.1320
Omneya Mashaly, Ahmed El Mahallawy, Tasneem Amer
INTRODUCTION: Sclerotherapy is an established treatment modality for oral vascular anomalies. A sclerosing agent such as Ethanolamine Oleate has been widely used for oral vascular malformation, especially low-flow venous lesions, however, pain is one of the most common postoperative complications. Therefore, Ethanolamine Oleate with an anesthetic agent may help in reducing postoperative pain in cases of oral venous malformation. AIM OF THE STUDY: To compare the effect of Ethanolamine Oleate as a sclerosing agent for oral venous malformation with and without an anesthetic agent in reducing postoperative pain and resolution of the lesion. MATERIALS AND METHODS: 16 patients with oral venous malformation were recruited and randomly allocated into two equal groups. Sclerotherapy with Ethanolamine Oleate was performed for all patients in Group A (Control Group) eight patients were injected with Ethanolamine Oleate alone and for Group B (Study Group) eight patients were injected with Ethanolamine Oleate mixed with Lidocaine. RESULTS: There was a statistically significant decrease between the two studied groups. Using the VAS scale, showed a significant decrease in post-operative pain reaching an (87.5%) success rate in Group B, especially two days postoperatively. CONCLUSION: This study confirmed the positive effect of intralesional injection of EO and Lidocaine in OVMs regarding postoperative pain and resolution of the lesion.
简介:硬化疗法是口腔血管异常的一种成熟的治疗方式。硬化剂如油酸乙醇胺已被广泛用于口腔血管畸形,特别是低流量静脉病变,然而,疼痛是最常见的术后并发症之一。因此,油酸乙醇胺与麻醉剂可能有助于减少口腔静脉畸形病例的术后疼痛。研究的目的:比较油酸乙醇胺作为口腔静脉畸形的硬化剂,在有麻醉剂和没有麻醉剂的情况下,在减少术后疼痛和缓解病变方面的效果。材料与方法:招募16例口腔静脉畸形患者,随机分为两组。A组(对照组)8例患者单独注射油酸乙醇胺,B组(研究组)8例患者注射油酸乙醇胺与利多卡因混合硬化治疗。结果:两组间比较,差异有统计学意义。VAS评分显示,B组患者术后疼痛明显减轻,成功率达87.5%,尤其是术后2天。结论:本研究证实了局部注射EO和利多卡因对OVMs术后疼痛和病变缓解的积极作用。
{"title":"INTRALESIONAL INJECTION OF ETHANOLAMINE OLEATE WITH OR WITHOUT LOCAL ANAESTHETIC AGENT TO ASSESS POSTOPERATIVE PAIN IN ORAL VENOUS MALFORMATIONS (A RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"Omneya Mashaly, Ahmed El Mahallawy, Tasneem Amer","doi":"10.21608/adjalexu.2022.167165.1320","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.167165.1320","url":null,"abstract":"INTRODUCTION: Sclerotherapy is an established treatment modality for oral vascular anomalies. A sclerosing agent such as Ethanolamine Oleate has been widely used for oral vascular malformation, especially low-flow venous lesions, however, pain is one of the most common postoperative complications. Therefore, Ethanolamine Oleate with an anesthetic agent may help in reducing postoperative pain in cases of oral venous malformation. AIM OF THE STUDY: To compare the effect of Ethanolamine Oleate as a sclerosing agent for oral venous malformation with and without an anesthetic agent in reducing postoperative pain and resolution of the lesion. MATERIALS AND METHODS: 16 patients with oral venous malformation were recruited and randomly allocated into two equal groups. Sclerotherapy with Ethanolamine Oleate was performed for all patients in Group A (Control Group) eight patients were injected with Ethanolamine Oleate alone and for Group B (Study Group) eight patients were injected with Ethanolamine Oleate mixed with Lidocaine. RESULTS: There was a statistically significant decrease between the two studied groups. Using the VAS scale, showed a significant decrease in post-operative pain reaching an (87.5%) success rate in Group B, especially two days postoperatively. CONCLUSION: This study confirmed the positive effect of intralesional injection of EO and Lidocaine in OVMs regarding postoperative pain and resolution of the lesion.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
KNOWLEDGE OF EGYPTIAN GENERAL DENTISTS, ENDODONTISTS, AND PEDIATRIC DENTISTS REGARDING MANAGEMENT OF TRAUMATIC DENTAL INJURIES IN CHILDREN: A CROSS SECTIONAL STUDY 埃及普通牙科医生、牙髓病学家和儿童牙科医生对儿童牙外伤处理的了解:横断面研究
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2023.244526.1426
Yasmine Elhamouly
INTRODUCTION : Traumatic dental injuries (TDIs) are common in childhood. Treatment options for TDIs are based on the extent and nature of the injury. General dentists play an important role in the treatment of TDIs. OBJECTIVE: this study aimed to assess the knowledge of general dental practitioners (GDPs) compared to pediatric dentists (PDs), and endodontists (EDs) regarding emergency management of TDIs and application of International Association of Dental Traumatology (IADT) guidelines in a sample of dentists in Alexandria, Egypt. MATERIAL AND METHODS: Participants completed a two-part questionnaire (ten questions covering demographic, professional, and personal data and 14 questions about given trauma cases scenarios) in electronic format to assess their knowledge regarding TDIs. One score was dedicated to each correct answer: score of 0-4= poor knowledge, scores 5-8, 9-11 and 12-14= moderate, good and excellent, respectively. Data was collected and transferred to a secured spread sheet. Frequencies and percentage were calculated for qualitative variables. Comparisons between the three categories were done using Chi-square test. Ordinal logistic regression was conducted to assess the association between dental specialties with knowledge score. Odds ratio (OR) and 95% confidence intervals (CI) were calculated. Significance was set at p value < 0.05. RESULTS: PDs and EDs had a higher knowledge score than GDPs (P= 0.01, B=11.19, 95%CI: 1.74, 71.77) and (P= 0.000, B= 36.18, 95%CI: 5.29, 247.28), respectively. Dentists who assessed their knowledge as comprehensive or sufficient had a higher knowledge score than those who assessed their knowledge as fragmentary (P= 0.000, B=24.58, 95%CI: 8.71, 69.30) and (P= 0.000, B= 7.93, 95%CI: 3.60, 17.48) respectively. CONCLUSIONS : The knowledge level of GDPs on TDIs was significantly lower than that of PDs and EDs, while no significant difference was encountered between PDs and EDs.
简介:创伤性牙损伤(TDIs)在儿童中很常见。tdi的治疗选择取决于损伤的程度和性质。普通牙医在治疗中耳炎中起着重要的作用。目的:本研究旨在评估普通牙科医生(GDPs)与儿科牙医(pd)和牙髓科医生(EDs)在TDIs应急管理方面的知识,以及国际牙科创伤学协会(IADT)指南在埃及亚历山大牙医样本中的应用。材料和方法:参与者完成了一份电子格式的两部分调查问卷(10个问题,涵盖人口统计、专业和个人数据,14个问题涉及给定的创伤病例场景),以评估他们对创伤性脑损伤的了解。每个正确答案都有一个分数:0-4分代表知识贫乏,5-8分、9-11分和12-14分分别代表中等、良好和优秀。数据被收集并转移到一个安全的电子表格。对定性变量计算频率和百分比。三组间比较采用卡方检验。采用有序logistic回归分析口腔专科与知识得分的关系。计算优势比(OR)和95%置信区间(CI)。p值< 0.05为显著性。结果:pd和EDs的知识得分分别高于GDPs (P= 0.01, B=11.19, 95%CI: 1.74, 71.77)和(P= 0.000, B= 36.18, 95%CI: 5.29, 247.28)。评价自己知识全面或充分的牙医的知识得分分别高于评价自己知识零碎的牙医(P= 0.000, B=24.58, 95%CI: 8.71, 69.30)和(P= 0.000, B= 7.93, 95%CI: 3.60, 17.48)。结论:国内生产总值对专科医生的知识水平显著低于专科医生和专科医生,而专科医生和专科医生之间无显著差异。
{"title":"KNOWLEDGE OF EGYPTIAN GENERAL DENTISTS, ENDODONTISTS, AND PEDIATRIC DENTISTS REGARDING MANAGEMENT OF TRAUMATIC DENTAL INJURIES IN CHILDREN: A CROSS SECTIONAL STUDY","authors":"Yasmine Elhamouly","doi":"10.21608/adjalexu.2023.244526.1426","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.244526.1426","url":null,"abstract":"INTRODUCTION : Traumatic dental injuries (TDIs) are common in childhood. Treatment options for TDIs are based on the extent and nature of the injury. General dentists play an important role in the treatment of TDIs. OBJECTIVE: this study aimed to assess the knowledge of general dental practitioners (GDPs) compared to pediatric dentists (PDs), and endodontists (EDs) regarding emergency management of TDIs and application of International Association of Dental Traumatology (IADT) guidelines in a sample of dentists in Alexandria, Egypt. MATERIAL AND METHODS: Participants completed a two-part questionnaire (ten questions covering demographic, professional, and personal data and 14 questions about given trauma cases scenarios) in electronic format to assess their knowledge regarding TDIs. One score was dedicated to each correct answer: score of 0-4= poor knowledge, scores 5-8, 9-11 and 12-14= moderate, good and excellent, respectively. Data was collected and transferred to a secured spread sheet. Frequencies and percentage were calculated for qualitative variables. Comparisons between the three categories were done using Chi-square test. Ordinal logistic regression was conducted to assess the association between dental specialties with knowledge score. Odds ratio (OR) and 95% confidence intervals (CI) were calculated. Significance was set at p value < 0.05. RESULTS: PDs and EDs had a higher knowledge score than GDPs (P= 0.01, B=11.19, 95%CI: 1.74, 71.77) and (P= 0.000, B= 36.18, 95%CI: 5.29, 247.28), respectively. Dentists who assessed their knowledge as comprehensive or sufficient had a higher knowledge score than those who assessed their knowledge as fragmentary (P= 0.000, B=24.58, 95%CI: 8.71, 69.30) and (P= 0.000, B= 7.93, 95%CI: 3.60, 17.48) respectively. CONCLUSIONS : The knowledge level of GDPs on TDIs was significantly lower than that of PDs and EDs, while no significant difference was encountered between PDs and EDs.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"70 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138622709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFECT OF ELECTRONIC CIGARETTES SMOKING ON COLOR STABILITY OF CAD/CAM ACRYLIC RESIN: IN VITRO STUDY 吸食电子香烟对 CAD/CAM 丙烯酸树脂颜色稳定性的影响:体内研究
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.152513.1302
Ahmed Mahmoud, Mohamed EL-Attar, Mohamed Abu Saied, Ingy Hassan
INTRODUCTION: The most common electronic nicotine delivery system is electronic cigarettes. Most of electronic cigarettes consist of a battery and electric heater used to aerosolize a liquid to produce vapor which the user inhales. Poly methyl methacrylate comes in contact with a variety of foods and beverages of different temperatures, as a result, it is prone to absorbing a variety of pollutants, altering its physical structure and appearance. OBJECTIVES: This study aimed to investigate the effects of electronic cigarettes smoking on color stability of CAD/CAM acrylic resin. MATERIAL AND METHODS: This study was in vitro study in which sixty specimens of CAD/CAM acrylic resin was exposed to aerosols which were flavored and non-flavored with nicotine content (0 mg, 6 mg and 12 mg). A portable suction machine was modified to simulate smoking in vivo. Each specimen was exposed to 20 cycles of aerosol released by a single ECIG device using the smoking chamber. Color measurements were performed using a calibrated spectrophotometer on the specimens before and after ECIG exposure RESULTS: Specimens exposed to flavorless 0 mg. nicotine aerosol showed the lowest delta E value 2.39 (±0.16) , while Specimens exposed to flavored 12 mg. nicotine showed the highest values 4.14 (±0.19). No significant difference in color change found between groups exposed to flavorless e-liquid, while a significant difference found between flavored 0 mg. nicotine and 12 mg. nicotine groups (P = 0.002).Also, a significant difference found between flavored 6 mg. nicotine and 12 mg. nicotine groups (P = 0.002). According to Two Way ANOVA, both flavor and nicotine contents have a significant effect on color change (P <0.0001). CONCLUSION: Exposure to flavored and non-flavored electronic cigarettes aerosol of different nicotine concentrations changed the color of acrylic resin. Both flavor and nicotine contents have a significant effect on color change.
简介:最常见的电子尼古丁输送系统是电子香烟。大多数电子烟由电池和电加热器组成,用于雾化液体产生蒸汽,使用者吸入。聚甲基丙烯酸甲酯与多种不同温度的食品和饮料接触,容易吸收多种污染物,改变其物理结构和外观。目的:研究吸电子烟对CAD/CAM丙烯酸树脂颜色稳定性的影响。材料和方法:本研究为体外研究,将60个CAD/CAM丙烯酸树脂样品暴露于含尼古丁(0 mg, 6 mg和12 mg)的调味和非调味气溶胶中。对便携式吸吸机进行了改进,以模拟体内吸烟。每个样本暴露于由单个ECIG装置使用吸烟室释放的气溶胶20次循环。使用校准的分光光度计对ECIG暴露前后的标本进行颜色测量结果:标本暴露于无味的0 mg。烟碱气雾剂的δ E值最低,为2.39(±0.16);尼古丁最高,为4.14(±0.19)。暴露于无味电子烟液的两组之间的颜色变化没有显著差异,而在0毫克的调味电子烟液中发现显著差异。尼古丁和12毫克。尼古丁组(P = 0.002)。此外,在调味的6毫克。尼古丁和12毫克。尼古丁组(P = 0.002)。双因素方差分析显示,风味和尼古丁含量对颜色变化均有显著影响(P <0.0001)。结论:不同尼古丁浓度的有味和无味电子烟气溶胶对丙烯酸树脂的颜色有影响。风味和尼古丁含量对颜色变化均有显著影响。
{"title":"EFFECT OF ELECTRONIC CIGARETTES SMOKING ON COLOR STABILITY OF CAD/CAM ACRYLIC RESIN: IN VITRO STUDY","authors":"Ahmed Mahmoud, Mohamed EL-Attar, Mohamed Abu Saied, Ingy Hassan","doi":"10.21608/adjalexu.2022.152513.1302","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.152513.1302","url":null,"abstract":"INTRODUCTION: The most common electronic nicotine delivery system is electronic cigarettes. Most of electronic cigarettes consist of a battery and electric heater used to aerosolize a liquid to produce vapor which the user inhales. Poly methyl methacrylate comes in contact with a variety of foods and beverages of different temperatures, as a result, it is prone to absorbing a variety of pollutants, altering its physical structure and appearance. OBJECTIVES: This study aimed to investigate the effects of electronic cigarettes smoking on color stability of CAD/CAM acrylic resin. MATERIAL AND METHODS: This study was in vitro study in which sixty specimens of CAD/CAM acrylic resin was exposed to aerosols which were flavored and non-flavored with nicotine content (0 mg, 6 mg and 12 mg). A portable suction machine was modified to simulate smoking in vivo. Each specimen was exposed to 20 cycles of aerosol released by a single ECIG device using the smoking chamber. Color measurements were performed using a calibrated spectrophotometer on the specimens before and after ECIG exposure RESULTS: Specimens exposed to flavorless 0 mg. nicotine aerosol showed the lowest delta E value 2.39 (±0.16) , while Specimens exposed to flavored 12 mg. nicotine showed the highest values 4.14 (±0.19). No significant difference in color change found between groups exposed to flavorless e-liquid, while a significant difference found between flavored 0 mg. nicotine and 12 mg. nicotine groups (P = 0.002).Also, a significant difference found between flavored 6 mg. nicotine and 12 mg. nicotine groups (P = 0.002). According to Two Way ANOVA, both flavor and nicotine contents have a significant effect on color change (P <0.0001). CONCLUSION: Exposure to flavored and non-flavored electronic cigarettes aerosol of different nicotine concentrations changed the color of acrylic resin. Both flavor and nicotine contents have a significant effect on color change.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138626656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFICACY OF HYPERBARIC OXYGEN THERAPY ON REGENERATION OF MANDIBULAR BONY DEFECTS IN RATS WITH INDUCED DIABETES MELLITUS 高压氧疗法对糖尿病大鼠下颌骨缺损再生的疗效
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.158877.1309
Rodina H. Eldisoky, Salwa Younes, Samia Omar, Hagar S. Gharib, Tarek A. Tamara
INTRODUCTION: Bone repair abnormalities have been associated with diabetes mellitus (DM), including inhibited osteoblastic differentiation, induced osteoblast apoptosis, and compromised angiogenesis. Thus, restoring critical-sized defects is challenging in clinical practice, especially in people with diabetes. Hyperbaric oxygen therapy (HBOT) can be used together with bone grafts to reconstruct these defects. OBJECTIVES: To evaluate the effect of HBOT on the regeneration of critical-sized defects in rats with induced diabetes mellitus. MATERIALS AND METHODS: Twelve adult male albino rats were divided into two groups of 6 animals each. Animals in both groups were given a single intraperitoneal injection of streptozotocin to induce DM. Critical-sized defects were created in the posterior mandibles and filled with beta-tricalcium phosphate (β -TCP). The study group was subjected to HBOT at (2.4 ATA) for 5 days per week for 90 minutes each. Animals were euthanized one week postoperatively. Bone regeneration was assessed histologically and histomorphometrically. Angiogenesis was evaluated by immunohistochemistry against vascular endothelial progenitor cell marker (CD34), and the microvessel density (MVD) was calculated. RESULTS: Histological and immunohistochemical results revealed superior bone regeneration and angiogenesis in the study group. These results were further confirmed by the histomorphometrical analysis which showed higher MVD and new bone surface area in the study group compared to the control group. CONCLUSIONS: HBOT enhanced bone regeneration, improved the regenerative effect of β -TCP, and increased angiogenesis in the defects.
骨修复异常与糖尿病(DM)相关,包括成骨细胞分化抑制、成骨细胞凋亡诱导和血管生成受损。因此,在临床实践中,修复临界尺寸的缺陷是具有挑战性的,特别是在糖尿病患者中。高压氧治疗(HBOT)可配合骨移植重建这些缺损。目的:探讨HBOT对诱导型糖尿病大鼠临界尺寸缺损再生的影响。材料与方法:将12只成年雄性白化大鼠分为两组,每组6只。两组动物均给予单次腹腔注射链脲佐菌素诱导糖尿病。在后下颌形成临界大小的缺损,并用β -磷酸三钙(β -TCP)填充。实验组接受(2.4 ATA) HBOT,每周5天,每次90分钟。术后1周对动物实施安乐死。用组织学和组织形态学方法评估骨再生。采用免疫组化方法检测血管内皮祖细胞标志物(CD34)的新生情况,计算微血管密度(MVD)。结果:组织学和免疫组化结果显示实验组骨再生和血管生成能力较强。组织形态学分析进一步证实了这一结果,实验组的MVD和新骨表面积均高于对照组。结论:HBOT能促进骨再生,提高β -TCP的再生效果,促进骨缺损血管生成。
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引用次数: 0
EVALUATION OF STABILITY AND CRESTAL BONE CHANGES AROUND IMPLANTS PLACED AT CRESTAL VERSUS SUBCRESTAL LEVEL IN CONTROLLED TYPE TWO DIABETIC PATIENTS 评估二型糖尿病患者在骨嵴与骨嵴下植入种植体的稳定性和骨嵴变化
Pub Date : 2023-12-01 DOI: 10.21608/adjalexu.2022.151775.1300
Asmaa Elserity, Abd El Aziz Khalil, Maha Talaab, Riham Fliefel
INTRODUCTION :Peri-implant bone level preservationis the key to maintainingperi-implant soft tissue and stability.Many studies have discussed the role of placing dental implants at various depths on crestal bone loss, but they were debatable. OBJECTIVES: To compare clinically and radiographically the effect of placing implants atcrestal versus subcrestal levels on the crestal bone lossand stability evaluation in controlled type 2diabetic patients. MATERIALS AND METHODS: 22 controlleddiabetic patients were randomized accordingto placement depth (group I: 11 implants were placed equicrestally) (group Ⅱ : 11implants were placed 1mm subcrestally). Stability of implants, clinical and radiographical assessment were done for both groups. RESULTS: 19 implants were included in our study (10 crestal and 9 subcrestal). There were no statistically significant differences in bleeding index and probing depth between the 2 groups while plaque index was greateramong subcrestal group. Crestal bone loss mesiodistally was significantly higherin crestal group, whilethere was no significant difference buccolingually between crestal and subcrestal groups. Stabilityvalues weresignificantly greater in subcrestal group at loading time. CONCLUSION: Sub-crestal implant placement is preferable for controlled type 2 diabetic patients as it decreases the probability of implant thread exposureprovided that careful oral hygiene care is followed and regular periodic checks to maintain peri-implantsoft tissue and dental bone health.
引言:种植体周围骨水平保存是维持种植体周围软组织和稳定性的关键。许多研究讨论了在不同深度放置牙种植体对牙冠骨丢失的作用,但它们是有争议的。目的:比较对照2型糖尿病患者在冠上和冠下水平放置种植体对冠骨丢失和稳定性评估的临床和影像学影响。材料与方法:22例对照糖尿病患者按放置深度随机选择(I组:11个种植体均匀放置)(Ⅱ组:11个种植体放置于牙下1mm)。两组均进行了种植体的稳定性、临床和影像学评估。结果:本研究共纳入19个种植体(10个冠下种植体,9个冠下种植体)。两组间出血指数、探诊深度差异无统计学意义,而牙冠下组斑块指数高于牙冠下组。牙冠组骨量中远端显著高于牙冠组,而牙冠组与牙下组骨量无显著差异。在加载时间,峰下组的稳定性值显著更高。结论:牙冠下种植体可降低2型糖尿病患者种植体线暴露的可能性,但前提是要注意口腔卫生,定期检查种植体周围软组织和牙骨健康。
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引用次数: 0
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Alexandria Dental Journal
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