Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.208810.1375
Mohamed Saeed, Mohamed Shokry, Ziad Mohmoud
BACKGROUND: Graftless sinus lift is one of the techniques that provides enough room for implant placement in the atrophic posterior maxilla. Blood clots can be thought of as bone-forming osteogenic graft material to which Osseo progenitors can circulate, differentiate, and regenerate bone. AIM OF THE STUDY: This study was conducted with the aim of evaluating the clinical effectiveness of using Fibrin glue versus Titanium platelet-rich fibrin (T-PRF) as the sole filling material in lateral sinus augmentation and simultaneous implant placement. MATERIALS AND METHODS: There were three groups each made up of ten participants: Study Groups 1 and 2 (S1 and S2), which received Fibrin glue and T-PRF as filling materials, respectively; and the negative Control Group (C). In the three groups, sinus floor augmentation via the lateral osteotomy approach and simultaneous implant placement were done. The patients were evaluated clinically in terms of pain, postoperative complications, and implant stability immediately postoperatively, after one week, and six months later. RESULTS: Between the three groups under study, no significant difference regarding pain was revealed, either immediately following surgery or one week later. Regarding implant stability, there was a significant increase in the mean Implant Stability Quotient (ISQ) value between Fibrin-glue Group (S1) that was 73.30 ± 4.06, and T-PRF Group (S2) that was 70.10 ± 2.81 and the Control Group (C) that was 64.0 ± 6.13 (p2<0.001, p3=0.015, respectively). However, no significant difference was found between the two study groups (S1, and S2) (p1 = 0.273).
{"title":"CLINICAL EVALUATION OF USING FIBLIN GLUE VERSUS TITANIUM PLATELET-RICH FIBRIN IN LATERAL SINUS LIFTING PROCEDURE (RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"Mohamed Saeed, Mohamed Shokry, Ziad Mohmoud","doi":"10.21608/adjalexu.2023.208810.1375","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.208810.1375","url":null,"abstract":"BACKGROUND: Graftless sinus lift is one of the techniques that provides enough room for implant placement in the atrophic posterior maxilla. Blood clots can be thought of as bone-forming osteogenic graft material to which Osseo progenitors can circulate, differentiate, and regenerate bone. AIM OF THE STUDY: This study was conducted with the aim of evaluating the clinical effectiveness of using Fibrin glue versus Titanium platelet-rich fibrin (T-PRF) as the sole filling material in lateral sinus augmentation and simultaneous implant placement. MATERIALS AND METHODS: There were three groups each made up of ten participants: Study Groups 1 and 2 (S1 and S2), which received Fibrin glue and T-PRF as filling materials, respectively; and the negative Control Group (C). In the three groups, sinus floor augmentation via the lateral osteotomy approach and simultaneous implant placement were done. The patients were evaluated clinically in terms of pain, postoperative complications, and implant stability immediately postoperatively, after one week, and six months later. RESULTS: Between the three groups under study, no significant difference regarding pain was revealed, either immediately following surgery or one week later. Regarding implant stability, there was a significant increase in the mean Implant Stability Quotient (ISQ) value between Fibrin-glue Group (S1) that was 73.30 ± 4.06, and T-PRF Group (S2) that was 70.10 ± 2.81 and the Control Group (C) that was 64.0 ± 6.13 (p2<0.001, p3=0.015, respectively). However, no significant difference was found between the two study groups (S1, and S2) (p1 = 0.273).","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"224 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141013017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.215970.1386
salma nabil, Gehan S. Kotry, Lamia Heikal, Yasmine Gaweesh
INTRODUCTION: For many muco-gingival deformities, autogenous soft tissue grafts are the gold standard treatment. The palate is the most typical site for soft tissue graft harvesting. Epithelialized graft harvesting technique is one of the most efficient. Yet, it leaves an open palatal wound that is only healed by secondary intention. Many dressing materials have been used -to cover and protect the donor site-either alone or combined with other biological materials as: non-eugenol and eugenol dressings, Collagen, hydrogels and, resin-based dressings. Melatonin is well known for its anti-oxidant and anti-inflammatory effects; it has the ability to decrease the effects of various pro-inflammatory mediators. It can scavenge free radicals and reduce oxidative stress, which is often associated with inflammation. Melatonin's ability to regulate the immune response and dampen the pro-inflammatory cascade has gained interest for potential therapeutic applications. Study objective: To assess the effect of topically applied melatonin loaded gelatin sponge on palatal wound healing. MATERIALS AND METHODS: Twenty-six surgical sites for free palatal graft procurement were included in the study. They were equally divided into two groups: Test group, the palatal donor site was covered by topical Melatonin loaded gelatin sponge. Control group, the site was covered by carbopol loaded gelatin sponge. Wound healing was evaluated using photo-digital planimetry on the day of surgery and, at seven days post-surgical. Healing index of Landry was used at the seventh day. Pain was assessed via VAS for a week from the day of surgery. RESULTS: Photo-digital planimetry showed that the test group exhibited more reduction in the percentages of wound area than control although it was not statistically significant. Healing index of Landry revealed no statistically significant difference between the two groups. No significant differences in VAS scores between the two groups. CONCLUSION: Melatonin could be beneficial in improving palatal wound healing.
简介：对于许多粘液性牙龈畸形，自体软组织移植是治疗的金标准。腭是最典型的软组织移植取材部位。上皮化移植物采集技术是最有效的技术之一。然而，这种方法会留下开放性腭部伤口，只能通过二次意向愈合。许多敷料已被用于覆盖和保护供体部位--无论是单独使用还是与其他生物材料结合使用，如：非丁香酚和丁香酚敷料、胶原蛋白、水凝胶和树脂敷料。褪黑素以其抗氧化和抗炎作用而闻名；它能够降低各种促炎介质的作用。它可以清除自由基，减少氧化应激，而氧化应激通常与炎症有关。褪黑素具有调节免疫反应和抑制促炎级联反应的能力，其潜在的治疗应用已引起人们的兴趣。研究目的评估局部应用褪黑素明胶海绵对腭部伤口愈合的影响。材料与方法：本研究纳入了 26 个用于游离腭植皮的手术部位。他们被平均分为两组：试验组：在腭供体部位局部覆盖含有褪黑素的明胶海绵。对照组：用含卡波普的明胶海绵覆盖供体部位。在手术当天和术后七天，使用光数字平面测量法评估伤口愈合情况。第七天时使用兰德里愈合指数。自手术当天起一周内，通过 VAS 对疼痛进行评估。结果：光电数字平面测量法显示，试验组比对照组的伤口面积减少了更多百分比，但没有统计学意义。兰德里愈合指数显示，两组之间的差异无统计学意义。两组的 VAS 评分无明显差异。结论：褪黑素有助于改善腭部伤口愈合。
{"title":"EFFECT OF TOPICAL MELATONIN LOADED GELATIN SPONGE ON PALATAL WOUND HEALING (RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"salma nabil, Gehan S. Kotry, Lamia Heikal, Yasmine Gaweesh","doi":"10.21608/adjalexu.2023.215970.1386","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.215970.1386","url":null,"abstract":"INTRODUCTION: For many muco-gingival deformities, autogenous soft tissue grafts are the gold standard treatment. The palate is the most typical site for soft tissue graft harvesting. Epithelialized graft harvesting technique is one of the most efficient. Yet, it leaves an open palatal wound that is only healed by secondary intention. Many dressing materials have been used -to cover and protect the donor site-either alone or combined with other biological materials as: non-eugenol and eugenol dressings, Collagen, hydrogels and, resin-based dressings. Melatonin is well known for its anti-oxidant and anti-inflammatory effects; it has the ability to decrease the effects of various pro-inflammatory mediators. It can scavenge free radicals and reduce oxidative stress, which is often associated with inflammation. Melatonin's ability to regulate the immune response and dampen the pro-inflammatory cascade has gained interest for potential therapeutic applications. Study objective: To assess the effect of topically applied melatonin loaded gelatin sponge on palatal wound healing. MATERIALS AND METHODS: Twenty-six surgical sites for free palatal graft procurement were included in the study. They were equally divided into two groups: Test group, the palatal donor site was covered by topical Melatonin loaded gelatin sponge. Control group, the site was covered by carbopol loaded gelatin sponge. Wound healing was evaluated using photo-digital planimetry on the day of surgery and, at seven days post-surgical. Healing index of Landry was used at the seventh day. Pain was assessed via VAS for a week from the day of surgery. RESULTS: Photo-digital planimetry showed that the test group exhibited more reduction in the percentages of wound area than control although it was not statistically significant. Healing index of Landry revealed no statistically significant difference between the two groups. No significant differences in VAS scores between the two groups. CONCLUSION: Melatonin could be beneficial in improving palatal wound healing.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.220174.1394
Marwah Shakir, Fatma Adam, Yasmin Gaweesh
BACKGROUND: Oral lichen planus (OLP) is a chronic autoimmune disorder. It mostly involves the skin, mucous membrane, and rarely the scalp and nails. It is an inflammatory condition driven by T-cells. Traditional treatment for OLP is topical steroids, which are frequently used to treat lesions with mild to moderate symptoms. Recent treatment modalities for oral lichen planus include micronutrients as antioxidants, including vitamin E, that modify the immune system function. AIM OF THE STUDY: The purpose of this study is to assess the clinical response to adjunctive oral systemic vitamin E therapy in erosive oral lichen planus patients. MATERIALS AND METHODS: 50 patients participated in this randomized, controlled clinical study. The erosive OLP patients were split into two parallel groups: 25 in group A, patients were administered oral systemic vitamin E adjunctive to topical corticosteroids. Group B: 25 patients received topical corticosteroids alone. Clinically, treatment responses were evaluated according to Thongprasom et al. scoring system before and after both treatment modalities. RESULTS: After 4 and 8 weeks of treatment, there was a significant decline in the Thongprasom scores in the research groups. Both the mean score values for the outcomes after four and eight weeks were more prominent in the test group. Throughout the clinical experiment, the test and control groups were statistically different. CONCLUSION: Systemic vitamin E adjunctive to topical corticosteroids has shown promising effects in the management of OLP with no side effects.
背景：口腔扁平苔藓（OLP）是一种慢性自身免疫性疾病。它主要累及皮肤、粘膜，很少累及头皮和指甲。它是一种由 T 细胞驱动的炎症性疾病。口腔扁平苔藓的传统治疗方法是外用类固醇激素，常用于治疗轻度至中度症状的皮损。最近治疗口腔扁平苔藓的方法包括作为抗氧化剂的微量营养素，其中包括维生素 E，它能改变免疫系统的功能。研究目的：本研究旨在评估侵蚀性口腔扁平苔藓患者对口服维生素 E 辅助治疗的临床反应。材料与方法：50 名患者参与了这项随机对照临床研究。侵蚀性口腔扁平苔藓患者被分成两个平行组：A组25名患者在局部使用皮质类固醇激素的同时口服维生素E。B组：25名患者只接受局部皮质类固醇激素治疗。在两种治疗方法前后，根据 Thongprasom 等人的评分系统对治疗反应进行临床评估。结果：治疗 4 周和 8 周后，研究组的 Thongprasom 评分均显著下降。测试组在 4 周和 8 周后的结果平均分值都更为突出。在整个临床实验过程中，试验组和对照组在统计学上存在差异。结论：局部皮质类固醇激素辅助全身维生素E治疗OLP效果良好，且无副作用。
{"title":"CLINICAL EVALUATION OF ADJUNCTIVE ORAL SYSTEMIC VITAMIN E THERAPY IN PATIENTS WITH EROSIVE ORAL LICHEN PLANUS (A RANDOMIZED CONTROLLED CLINICALC TRIAL)","authors":"Marwah Shakir, Fatma Adam, Yasmin Gaweesh","doi":"10.21608/adjalexu.2023.220174.1394","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.220174.1394","url":null,"abstract":"BACKGROUND: Oral lichen planus (OLP) is a chronic autoimmune disorder. It mostly involves the skin, mucous membrane, and rarely the scalp and nails. It is an inflammatory condition driven by T-cells. Traditional treatment for OLP is topical steroids, which are frequently used to treat lesions with mild to moderate symptoms. Recent treatment modalities for oral lichen planus include micronutrients as antioxidants, including vitamin E, that modify the immune system function. AIM OF THE STUDY: The purpose of this study is to assess the clinical response to adjunctive oral systemic vitamin E therapy in erosive oral lichen planus patients. MATERIALS AND METHODS: 50 patients participated in this randomized, controlled clinical study. The erosive OLP patients were split into two parallel groups: 25 in group A, patients were administered oral systemic vitamin E adjunctive to topical corticosteroids. Group B: 25 patients received topical corticosteroids alone. Clinically, treatment responses were evaluated according to Thongprasom et al. scoring system before and after both treatment modalities. RESULTS: After 4 and 8 weeks of treatment, there was a significant decline in the Thongprasom scores in the research groups. Both the mean score values for the outcomes after four and eight weeks were more prominent in the test group. Throughout the clinical experiment, the test and control groups were statistically different. CONCLUSION: Systemic vitamin E adjunctive to topical corticosteroids has shown promising effects in the management of OLP with no side effects.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141129677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.214862.1384
Moustafa Samy, A. Sharara, Gaffar El Halawani
INTRODUCTION: One of the recent grafting materials is mineralized plasmatic matrix (MPM). It is an autologous blood product with a high concentration of platelets and fibrin in addition to bone particles. Its fibrin, combined with the bone particles and the grafting material, can be shaped easily. MPM became favourable in improving treatment outcomes of dental implants due to the efficiency of bone formation. OBJECTIVES: To compare clinically and radiologically the efficiency of MPM versus Beta-Tricalcium phosphate (β-TCP) in osseointegration during immediate placement of implant at the mandibular molar area. MATERIALS AND METHODS: Randomized clinical trial done on sixteen patients, with strongly decayed mandibular molars. All patients were divided into 2 equal groups: In group A, 8 immediate implants were placed in mandibular molars using MPM as a graft in the peri-implant gap. While in group B, eight immediate implants were placed in mandibular molars using β-TCP as a graft in the peri-implant gap. Bone density, marginal bone loss, implant stability and peri-implant probing depth were evaluated clinically and radiologically after 6 months for all patients. RESULTS: Group A showed statistically higher mean implant stability and bone density percent change after six months than group B. However the mean marginal bone loss was statistically lower. For both groups, during the six months follow up period, there was no significant difference regarding the peri-implant probing depth. CONCLUSION: MPM enhances formation of bone in mandibular area and provides better bone density, implant stability and less marginal bone loss compared to β-TCP.
{"title":"EVALUATION OF MINERALIZED PLASMATIC MATRIX AS A GRAFTING MATERIAL VERSUS BETA TRICALCIUM PHOSPHATE IN IMMEDIATE IMPLANT PLACEMENT OF MANDIBULAR MOLARS (A RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"Moustafa Samy, A. Sharara, Gaffar El Halawani","doi":"10.21608/adjalexu.2023.214862.1384","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.214862.1384","url":null,"abstract":"INTRODUCTION: One of the recent grafting materials is mineralized plasmatic matrix (MPM). It is an autologous blood product with a high concentration of platelets and fibrin in addition to bone particles. Its fibrin, combined with the bone particles and the grafting material, can be shaped easily. MPM became favourable in improving treatment outcomes of dental implants due to the efficiency of bone formation. OBJECTIVES: To compare clinically and radiologically the efficiency of MPM versus Beta-Tricalcium phosphate (β-TCP) in osseointegration during immediate placement of implant at the mandibular molar area. MATERIALS AND METHODS: Randomized clinical trial done on sixteen patients, with strongly decayed mandibular molars. All patients were divided into 2 equal groups: In group A, 8 immediate implants were placed in mandibular molars using MPM as a graft in the peri-implant gap. While in group B, eight immediate implants were placed in mandibular molars using β-TCP as a graft in the peri-implant gap. Bone density, marginal bone loss, implant stability and peri-implant probing depth were evaluated clinically and radiologically after 6 months for all patients. RESULTS: Group A showed statistically higher mean implant stability and bone density percent change after six months than group B. However the mean marginal bone loss was statistically lower. For both groups, during the six months follow up period, there was no significant difference regarding the peri-implant probing depth. CONCLUSION: MPM enhances formation of bone in mandibular area and provides better bone density, implant stability and less marginal bone loss compared to β-TCP.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"223 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141013028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.208333.1372
Dina omara, Ahmed Shaaban, Marwa G. Noureldin
INTRODUCTION: If a tissue's integrity has been compromised, most body tissues can go through wound healing and leave behind scars when they recover. Mesotherapy is a non-invasive transdermal injection into the skin which stimulating fibroblasts for collagen and elastin biosynthesis and facilitating cell-to-cell communication that can be used to heal face scars. OBJECTIVE: This study evaluated the efficacy of mesotherapy using both qualitative assessment and quantitative measurements in comparison to control group. MATERIALS AND METHODS: Twenty-four patients with oblique or vertical forehead lacerations who underwent primary closure within five days. Randomly divided into two groups: Group 1 (n=12) was given mesotherapy (microneedling) and group 2 (n=12) was given no further treatment. At the 1, 3, and 6-month follow-up appointments, the Vancouver scar scale (VSS) scores and wound diameter were assessed, along with clinical pictures and an assessment of the scar's pigmentation. RESULTS: At the 1-month follow-up, both groups had significantly improved. After 3 months, follow-up, the mesotherapy (microneedling) group displayed more significant changes in VSS, wound breadth, and color difference scores than the control group. Patients from both groups relapsed to their original records during the follow-up at 6 months. CONCLUSION: Significant progress was achieved in the VSS and in the wound width with Mesotherapy (microneedling) group compared to the control group. All the major changes were observed in the 3 and 6-month visits.
{"title":"CLINICAL EVALUATION OF MESOTHERAPY ON THE IMPROVEMENT OF FACIAL SCARS (RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"Dina omara, Ahmed Shaaban, Marwa G. Noureldin","doi":"10.21608/adjalexu.2023.208333.1372","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.208333.1372","url":null,"abstract":"INTRODUCTION: If a tissue's integrity has been compromised, most body tissues can go through wound healing and leave behind scars when they recover. Mesotherapy is a non-invasive transdermal injection into the skin which stimulating fibroblasts for collagen and elastin biosynthesis and facilitating cell-to-cell communication that can be used to heal face scars. OBJECTIVE: This study evaluated the efficacy of mesotherapy using both qualitative assessment and quantitative measurements in comparison to control group. MATERIALS AND METHODS: Twenty-four patients with oblique or vertical forehead lacerations who underwent primary closure within five days. Randomly divided into two groups: Group 1 (n=12) was given mesotherapy (microneedling) and group 2 (n=12) was given no further treatment. At the 1, 3, and 6-month follow-up appointments, the Vancouver scar scale (VSS) scores and wound diameter were assessed, along with clinical pictures and an assessment of the scar's pigmentation. RESULTS: At the 1-month follow-up, both groups had significantly improved. After 3 months, follow-up, the mesotherapy (microneedling) group displayed more significant changes in VSS, wound breadth, and color difference scores than the control group. Patients from both groups relapsed to their original records during the follow-up at 6 months. CONCLUSION: Significant progress was achieved in the VSS and in the wound width with Mesotherapy (microneedling) group compared to the control group. All the major changes were observed in the 3 and 6-month visits.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.206854.1369
Mohamed Marey, Sanaa Hussein, Moustafa Aboushelib
INTRODUCTION: Marginal fit is critical for the success of dental restorations. Zirconia full coverage restorations can be fabricated either chair-side or in a milling center. OBJECTIVE: To evaluate the fit accuracy of all ceramic restorations fabricated by two different CAD/CAM systems using a sectional method. MATERIAL AND METHODS: A lower first molar was prepared for a full coverage restoration, it was laser scanned (Ceramill map 400) and 24 replicas were milled using acrylic CAD/CAM block (Ceramill TEMP). Half of the dies were scanned using a closed system (CEREC inLab MC X5) while the other half used an open system (Ceramill motion 2). Zirconia restorations (Monolithic Katana zirconia) were milled from each system. Sectional method where each restoration was cut into thin sections (Buehler Isomet 4000 Linear Precision Saw) after cementation by self-adhesive resin cement (RelyX™ Unicem). A stereomicroscope was used for measurement. (n=24 α= 0.05). RESULTS: There was a significant difference (t=2.387, P<0.030) as the open system was better than the closed system at the axial sites. CONCLUSIONS: within the limitations of this study, better marginal qualities were achieved using an open CAD/CAM system.
{"title":"FIT ACCURACY OF OPEN VERSUS CLOSED CAD/CAM SYSTEMS USING A SECTIONAL METHOD","authors":"Mohamed Marey, Sanaa Hussein, Moustafa Aboushelib","doi":"10.21608/adjalexu.2023.206854.1369","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.206854.1369","url":null,"abstract":"INTRODUCTION: Marginal fit is critical for the success of dental restorations. Zirconia full coverage restorations can be fabricated either chair-side or in a milling center. OBJECTIVE: To evaluate the fit accuracy of all ceramic restorations fabricated by two different CAD/CAM systems using a sectional method. MATERIAL AND METHODS: A lower first molar was prepared for a full coverage restoration, it was laser scanned (Ceramill map 400) and 24 replicas were milled using acrylic CAD/CAM block (Ceramill TEMP). Half of the dies were scanned using a closed system (CEREC inLab MC X5) while the other half used an open system (Ceramill motion 2). Zirconia restorations (Monolithic Katana zirconia) were milled from each system. Sectional method where each restoration was cut into thin sections (Buehler Isomet 4000 Linear Precision Saw) after cementation by self-adhesive resin cement (RelyX™ Unicem). A stereomicroscope was used for measurement. (n=24 α= 0.05). RESULTS: There was a significant difference (t=2.387, P<0.030) as the open system was better than the closed system at the axial sites. CONCLUSIONS: within the limitations of this study, better marginal qualities were achieved using an open CAD/CAM system.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"289 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.214772.1383
sahar elgohary
INTRODUCTION: Non-carious enamel loss is becoming more prevalent due to modern habits which lead to increased levels of dentinal hypersensitivity (DH). DH manifests through dental abrasion, erosion, etc. When dentin is exposed, external stimuli can cause excessive pulpal pain response. Dental adhesives/restorations and desensitizers have been developed for obliteration of dentinal tubules (DTs) and treatment of DH. OBJECTIVES: To clinically evaluate the effectiveness of a glutaraldehyde-based desensitizer (Gluma™ Desensitizer Heraus-Kulzer, Hanau, Germany) vs conventional universal bonding agent (Scotchbond™ Universal Adhesive) in minimizing cervical dentin hypersensitivity (CDH) throughout a 6-months follow-up period. MATERIAL AND METHODS: 14 patients having a minimum of two contralateral teeth with CDH were allocated for a split-mouth, double-blind, randomized controlled trial. Each Patient received Gluma™ Desensitizer on one side vs Scotchbond™ Universal Adhesive on the other side. A total of three desensitization sessions were performed at 5 days interval. For assessment of hypersensitivity levels, air-blast and tactile Visual Analog Scale (VAS) sensitivity scores were evaluated at baseline (T0), immediately after each desensitizing session (T1,T2,T3), and at the 1st (T4), 3rd (T5), 6th (T6) months of follow-up. RESULTS: Both agents reduced CDH significantly over the course of the study. At T6, mean air-blast sensitivity VAS scores demonstrated statistically nonsignificant difference between groups (p=0.493). Probe sensitivity VAS scores recorded significant statistical difference between groups. CONCLUSIONS: Gluma desensitizer and Scotchbond Universal Adhesive resulted equally in a reduction of pain intensity for patients with DH. No advantage was detected for the use of one material over the other.
{"title":"THE EFFECT OF A RESIN-BASED DESENSITIZER CONTAINING GLUTARALDEHYDE ON CERVICAL DENTIN HYPERSENSITIVITY: A RANDOMIZED CONTROLLED CLINICAL TRIAL","authors":"sahar elgohary","doi":"10.21608/adjalexu.2023.214772.1383","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.214772.1383","url":null,"abstract":"INTRODUCTION: Non-carious enamel loss is becoming more prevalent due to modern habits which lead to increased levels of dentinal hypersensitivity (DH). DH manifests through dental abrasion, erosion, etc. When dentin is exposed, external stimuli can cause excessive pulpal pain response. Dental adhesives/restorations and desensitizers have been developed for obliteration of dentinal tubules (DTs) and treatment of DH. OBJECTIVES: To clinically evaluate the effectiveness of a glutaraldehyde-based desensitizer (Gluma™ Desensitizer Heraus-Kulzer, Hanau, Germany) vs conventional universal bonding agent (Scotchbond™ Universal Adhesive) in minimizing cervical dentin hypersensitivity (CDH) throughout a 6-months follow-up period. MATERIAL AND METHODS: 14 patients having a minimum of two contralateral teeth with CDH were allocated for a split-mouth, double-blind, randomized controlled trial. Each Patient received Gluma™ Desensitizer on one side vs Scotchbond™ Universal Adhesive on the other side. A total of three desensitization sessions were performed at 5 days interval. For assessment of hypersensitivity levels, air-blast and tactile Visual Analog Scale (VAS) sensitivity scores were evaluated at baseline (T0), immediately after each desensitizing session (T1,T2,T3), and at the 1st (T4), 3rd (T5), 6th (T6) months of follow-up. RESULTS: Both agents reduced CDH significantly over the course of the study. At T6, mean air-blast sensitivity VAS scores demonstrated statistically nonsignificant difference between groups (p=0.493). Probe sensitivity VAS scores recorded significant statistical difference between groups. CONCLUSIONS: Gluma desensitizer and Scotchbond Universal Adhesive resulted equally in a reduction of pain intensity for patients with DH. No advantage was detected for the use of one material over the other.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"25 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.232229.1411
Aya shehata, S. Younis, Nagah Rashad, Ahmed Mohamed
BACKGROUND: Cisplatin, a platinum-based chemical, is an exceedingly effective anti-cancer medication that is extensively utilized in treating several types of human neoplasms. Nevertheless, this treatment modality exhibits several drawbacks, including the occurrence of dose-dependent adverse effects such as cytotoxicity. The submandibular salivary gland is classified as one of the principal paired glands situated in an extraoral location. In humans, the submandibular glands are around half the size of the parotid gland. However, in rats, the submandibular gland is the largest among the three primary gland types. OBJECTIVES: to evaluate the cytotoxic effects induced by cisplatin on the submandibular salivary glands of albino rats. MATERIALS AND METHODS: A total of 30 adult albino male rats were divided into two groups, Gp I (control group) and Gp II (Cisplatin group). Rats in Gp II were administered a single intraperitoneal injection of 8 mg/kg of Cisplatin. At the end of the experiment (4 weeks), all rats were subjected to euthanasia. The submandibular salivary glands were removed and processed for histological and ultrastructural examination. RESULTS: The submandibular salivary glands of the cisplatin group were observed using histological and ultrastructural analysis, revealing evidence of atrophy and degeneration in the acinar cells as apoptotic nuclei and cytoplasmic vacuolization. Striated and granular convoluted ducts showed pyknotic nuclei, partial loss of basal striations and loss of mitochondrial internal structure. CONCLUSION: Cisplatin produced obvious degenerative changes on submandibular glands of albino rats.
背景：顺铂是一种铂类化学物质，是一种非常有效的抗癌药物，被广泛用于治疗多种类型的人类肿瘤。然而，这种治疗方式也存在一些缺点，包括会出现细胞毒性等剂量依赖性不良反应。颌下腺是位于口腔外的主要成对腺体之一。人类颌下腺的大小约为腮腺的一半。然而，在大鼠体内，颌下腺是三种主要腺体类型中最大的一种。目的：评估顺铂对白化大鼠颌下唾液腺的细胞毒性作用。材料与方法：将 30 只成年白化雄性大鼠分为两组，Gp I 组（对照组）和 Gp II 组（顺铂组）。Gp II 组大鼠腹腔注射 8 毫克/千克顺铂。实验结束时（4 周），所有大鼠均被安乐死。取出大鼠的颌下腺唾液腺，进行组织学和超微结构检查。结果：通过组织学和超微结构分析观察顺铂组大鼠的颌下腺，结果显示尖腺细胞出现萎缩和变性，表现为细胞核凋亡和胞浆空泡化。条状和颗粒状厥管显示出细胞核脓结、部分基底条纹消失和线粒体内部结构缺失。结论：顺铂会对白化大鼠的颌下腺产生明显的退行性变化。
{"title":"CISPLATIN INDUCED INJURY ON RAT SUBMANDIBULAR SALIVARY GLAND (HISTOLOGICAL AND ULTRASTRUCTURAL EVALUATION)","authors":"Aya shehata, S. Younis, Nagah Rashad, Ahmed Mohamed","doi":"10.21608/adjalexu.2023.232229.1411","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.232229.1411","url":null,"abstract":"BACKGROUND: Cisplatin, a platinum-based chemical, is an exceedingly effective anti-cancer medication that is extensively utilized in treating several types of human neoplasms. Nevertheless, this treatment modality exhibits several drawbacks, including the occurrence of dose-dependent adverse effects such as cytotoxicity. The submandibular salivary gland is classified as one of the principal paired glands situated in an extraoral location. In humans, the submandibular glands are around half the size of the parotid gland. However, in rats, the submandibular gland is the largest among the three primary gland types. OBJECTIVES: to evaluate the cytotoxic effects induced by cisplatin on the submandibular salivary glands of albino rats. MATERIALS AND METHODS: A total of 30 adult albino male rats were divided into two groups, Gp I (control group) and Gp II (Cisplatin group). Rats in Gp II were administered a single intraperitoneal injection of 8 mg/kg of Cisplatin. At the end of the experiment (4 weeks), all rats were subjected to euthanasia. The submandibular salivary glands were removed and processed for histological and ultrastructural examination. RESULTS: The submandibular salivary glands of the cisplatin group were observed using histological and ultrastructural analysis, revealing evidence of atrophy and degeneration in the acinar cells as apoptotic nuclei and cytoplasmic vacuolization. Striated and granular convoluted ducts showed pyknotic nuclei, partial loss of basal striations and loss of mitochondrial internal structure. CONCLUSION: Cisplatin produced obvious degenerative changes on submandibular glands of albino rats.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"265 43‐47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.218122.1390
Aliaa A Habib, A. Sharara, Ahmed O. Sweedan, Tarek N Yousry
INTRODUCTION: Alignment of dental arches in orthognathic treatment after undergoing Le Fort I osteotomy or bilateral sagittal split osteotomy relies on the use of intermediate and final occlusal splints, which do not provide precise control over the positioning of the condyle and ramus segments. AIM OF THE STUDY: To clinically and radiographically assess the accuracy of CAD/CAM surgical guide for condylar positioning in the bilateral sagittal split osteotomy. MATERIALS AND METHODS: The study recruited eight patients who had non-syndromic dentofacial deformity and underwent Bilateral Sagittal Split Osteotomy (BSSO) with or without maxillary osteotomy. Surgery was planned according to (CAD/CAM) technology. After osteotomy, a preoperative guide was used, followed by a repositioning guide. Computed tomography scans were conducted on all patients one week preoperatively, immediately, and three months postoperatively to assess the condylar position and facial symmetry. RESULTS: The data are presented as median values with the 25th and 75th percentiles. Eight patients (37.50% females and 62.50% males) between the ages of 19 and 24 underwent BSSO with or without LeFort I maxillary advancement. The surgical procedure successfully corrected their skeletal deformities. The absolute change between immediate postoperative and preoperative condylar angle was 0.15 [0.00-0.3]°. The absolute change between three months postoperative and preoperative Condylar Angle was 0.20 [0.00-0.30]°. CONCLUSION: The stability of the condylar head in position and patient postoperative occlusion is well assessed by 3D condylar positioning devices designed and manufactured by CAD/CAM technology in the mandibular BSSO.
简介：在进行 Le Fort I 截骨术或双侧矢状劈开截骨术后的正颌治疗中，牙弓的对齐依赖于中间和最终咬合夹板的使用，而中间和最终咬合夹板无法精确控制髁突和臼齿的定位。研究目的：对双侧矢状劈开截骨术中髁状突定位的 CAD/CAM 手术导板的准确性进行临床和影像学评估。材料与方法：研究招募了八名非综合畸形牙颌面畸形患者，他们接受了双侧矢状面劈开截骨术（BSSO），同时接受或不接受上颌骨截骨术。手术根据（CAD/CAM）技术进行规划。截骨后，使用术前指南，然后使用重新定位指南。对所有患者进行术前一周、术后即刻和术后三个月的计算机断层扫描，以评估髁突位置和面部对称性。结果：数据以中位数和第 25 和第 75 百分位数表示。八名年龄在 19 至 24 岁之间的患者（37.50% 为女性，62.50% 为男性）接受了 BSSO，同时接受或不接受 LeFort I 上颌骨前移术。手术成功矫正了他们的骨骼畸形。术后即刻与术前髁状突角度的绝对变化为 0.15 [0.00-0.3]°。术后三个月与术前髁突角度的绝对变化为 0.20 [0.00-0.30]°。结论：在下颌BSSO中，通过CAD/CAM技术设计和制造的三维髁突定位装置可以很好地评估髁突头位置的稳定性和患者术后的咬合情况。
{"title":"ACCURACY OF COMPUTER-ASSISTED DESIGN AND MANUFACTURED (CAD/CAM) THREE-DIMENSIONAL (3D) DEVICE FOR CONDYLAR POSITIONING IN MANDIBULAR BILATERAL SAGITTAL SPLIT OSTEOTOMY (CLINICAL TRIAL)","authors":"Aliaa A Habib, A. Sharara, Ahmed O. Sweedan, Tarek N Yousry","doi":"10.21608/adjalexu.2023.218122.1390","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.218122.1390","url":null,"abstract":"INTRODUCTION: Alignment of dental arches in orthognathic treatment after undergoing Le Fort I osteotomy or bilateral sagittal split osteotomy relies on the use of intermediate and final occlusal splints, which do not provide precise control over the positioning of the condyle and ramus segments. AIM OF THE STUDY: To clinically and radiographically assess the accuracy of CAD/CAM surgical guide for condylar positioning in the bilateral sagittal split osteotomy. MATERIALS AND METHODS: The study recruited eight patients who had non-syndromic dentofacial deformity and underwent Bilateral Sagittal Split Osteotomy (BSSO) with or without maxillary osteotomy. Surgery was planned according to (CAD/CAM) technology. After osteotomy, a preoperative guide was used, followed by a repositioning guide. Computed tomography scans were conducted on all patients one week preoperatively, immediately, and three months postoperatively to assess the condylar position and facial symmetry. RESULTS: The data are presented as median values with the 25th and 75th percentiles. Eight patients (37.50% females and 62.50% males) between the ages of 19 and 24 underwent BSSO with or without LeFort I maxillary advancement. The surgical procedure successfully corrected their skeletal deformities. The absolute change between immediate postoperative and preoperative condylar angle was 0.15 [0.00-0.3]°. The absolute change between three months postoperative and preoperative Condylar Angle was 0.20 [0.00-0.30]°. CONCLUSION: The stability of the condylar head in position and patient postoperative occlusion is well assessed by 3D condylar positioning devices designed and manufactured by CAD/CAM technology in the mandibular BSSO.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"229 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.212759.1380
Hesham Abdou, Noha Dessoky, Ossama Sweedan
BACKGROUND : The craniomaxillofacial trauma field is in continuous evolution and modernizations owing to the implementation of computer-aided design and manufacturing (CAD-CAM), creation of a preoperative anatomically reduced three-dimensional (3D) bone model has the potential to drastically reduce operating room time and operating room costs. Aim: Was to evaluate the clinical performance and the state of postoperative occlusion of a pre-adapted miniplates using 3D printed for the treatment of mandibular fractures. MATERIALS AND METHODS: 10 patients had recent mandibular fracture was treated using pre-adapted miniplates on 3D model. Fixation time was assessed intraoperatively. Clinical follow up was conducted after 24-hours, one, four, six, twelve and twenty-four weeks. In addition, a radiographic investigation was performed after twelve weeks to estimate the mean bone density across the fracture line. RESULTS: The study male to female ratio was 2.33:1 with mean age of 27.40 ± 5.38 years. The mean reported intraoperative fixation time was 9.43 ± 4.25 min. all patients reported a highly statistically significant improvement in the assessed clinical parameters. Across the radiographic follow up period, all of the patients reported a highly statistically significant increase in the mean bone density values (p<0.001*). CONCLUSION: the use of preoperatively adapted fixation plates in mandibular fracture management was associated with optimal occlusal and anatomical patient rehabilitation with decline in operating time while at the same time minimal increase in the processing time.
{"title":"TITLE: EVALUATION OF THREE DIMENSIONAL PRINTING AND PREOPERATIVE ADAPTATION OF MINIPLATES IN TREATMENT OF MANDIBULAR FRACTURES (CLINICAL TRIAL)","authors":"Hesham Abdou, Noha Dessoky, Ossama Sweedan","doi":"10.21608/adjalexu.2023.212759.1380","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.212759.1380","url":null,"abstract":"BACKGROUND : The craniomaxillofacial trauma field is in continuous evolution and modernizations owing to the implementation of computer-aided design and manufacturing (CAD-CAM), creation of a preoperative anatomically reduced three-dimensional (3D) bone model has the potential to drastically reduce operating room time and operating room costs. Aim: Was to evaluate the clinical performance and the state of postoperative occlusion of a pre-adapted miniplates using 3D printed for the treatment of mandibular fractures. MATERIALS AND METHODS: 10 patients had recent mandibular fracture was treated using pre-adapted miniplates on 3D model. Fixation time was assessed intraoperatively. Clinical follow up was conducted after 24-hours, one, four, six, twelve and twenty-four weeks. In addition, a radiographic investigation was performed after twelve weeks to estimate the mean bone density across the fracture line. RESULTS: The study male to female ratio was 2.33:1 with mean age of 27.40 ± 5.38 years. The mean reported intraoperative fixation time was 9.43 ± 4.25 min. all patients reported a highly statistically significant improvement in the assessed clinical parameters. Across the radiographic follow up period, all of the patients reported a highly statistically significant increase in the mean bone density values (p<0.001*). CONCLUSION: the use of preoperatively adapted fixation plates in mandibular fracture management was associated with optimal occlusal and anatomical patient rehabilitation with decline in operating time while at the same time minimal increase in the processing time.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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