Pub Date : 2024-01-05DOI: 10.21608/adjalexu.2023.242356.1423
Hagar Abdel Fattah, Marwa Essawy, Amira Eissa
OBJECTIVE: The presented work was conducted to test the effectiveness of activated charcoal on the lingual mucosa of male rats subjected to the immunosuppressive drug tacrolimus. DESIGN: After random allocation of thirty healthy male Wistar albino rats into three groups (10 per group), in group 1 {control group} animals received saline, whereas those in group 2 {the tacrolimus (TAC) group} received daily subcutaneous injections of the immunosuppressant for 3 weeks. In the third cohort group 3{tacrolimus and activated charcoal; TAC+AC}, rats received activated charcoal orally administrated beside the TAC for 3 weeks. After three weeks of treatment, the evaluation of dissected tongues exempted histological, immunohistochemical, and morphometrical analyses. RESULTS: Histological findings revealed mucosal and connective tissue degenerative changes induced by TAC. However, the AC group showed the preserved structure of the lingual mucosa and associated minor salivary glands. The immunohistochemical detection of Melan-A revealed the profound drop in the mean area percent and optical density of melanophages to 0.82 ± 0.2% and 0.12 ± 0.01, respectively, upon AC counteraction of TAC melanosis. CONCLUSIONS: AC exerted protective action against the degenerative effect of TAC on the lingual mucosa, encouraging its adjuvant uptake throughout the immunosuppressants course.
{"title":"Activated charcoal: A natural protective measure against the lingual degenerative effect of tacrolimus immunosuppressant","authors":"Hagar Abdel Fattah, Marwa Essawy, Amira Eissa","doi":"10.21608/adjalexu.2023.242356.1423","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.242356.1423","url":null,"abstract":"OBJECTIVE: The presented work was conducted to test the effectiveness of activated charcoal on the lingual mucosa of male rats subjected to the immunosuppressive drug tacrolimus. DESIGN: After random allocation of thirty healthy male Wistar albino rats into three groups (10 per group), in group 1 {control group} animals received saline, whereas those in group 2 {the tacrolimus (TAC) group} received daily subcutaneous injections of the immunosuppressant for 3 weeks. In the third cohort group 3{tacrolimus and activated charcoal; TAC+AC}, rats received activated charcoal orally administrated beside the TAC for 3 weeks. After three weeks of treatment, the evaluation of dissected tongues exempted histological, immunohistochemical, and morphometrical analyses. RESULTS: Histological findings revealed mucosal and connective tissue degenerative changes induced by TAC. However, the AC group showed the preserved structure of the lingual mucosa and associated minor salivary glands. The immunohistochemical detection of Melan-A revealed the profound drop in the mean area percent and optical density of melanophages to 0.82 ± 0.2% and 0.12 ± 0.01, respectively, upon AC counteraction of TAC melanosis. CONCLUSIONS: AC exerted protective action against the degenerative effect of TAC on the lingual mucosa, encouraging its adjuvant uptake throughout the immunosuppressants course.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"57 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139536083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.157860.1308
Ahmed Amin, Nayera A. Mokhless, Mahmoud Aboelseoud
INTRODUCTION: Endodontic treatment requires chemo-mechanical preparation of root canal to minimize the intracanal bacterial load. However, mechanical debridement results in smear layer formation containing infected debris requiring its removal before obturation. AIM OF THE STUDY: To assess the efficacy of Morinda Citrifolia juice (MCJ) as final irrigation protocol associated with manual dynamic agitation on smear layer removal by using scanning electron microscope. MATERIALS AND METHODS: Forty-five human mandibular permanent premolar teeth with single canals were decoronated to a standard length of 15mm and instrumented using ProTaper Next rotary files (X3). Roots were divided into 3 equal groups (n=15) according to the final irrigant used: Group I: 6% MCJ, Group II: 6% MCJ + 17% EDTA, Group III (control group): 2.5% NaOCl + 17% EDTA. Manual dynamic agitation (MDA) was used to activate the irrigants in all groups. Teeth were then prepared for scanning electron microscopy evaluation, and smear layer removal was assessed.. Comparisons between the study groups were done using Kruskal Wallis test, while comparisons of different regions within each group were done using Friedman test. RESULTS: Along complete canal length, no significant difference was found between 6%MCJ+17% EDTA and 2.5% NaOCl + 17% EDTA (p=0.29). However, a significant difference was noted between 6%MCJ and 2.5% NaOCl + 17% EDTA (p=0.001). In all groups, the coronal third showed the best results (P = 0.02) and the apical third showed the worst (P = 0.007). CONCLUSION: The use of 6%MCJ+17% EDTA associated with MDA could be an alternative to 2.5% NaOCl + 17% EDTA for smear layer removal, however, MCJ alone isn’t effective in smear layer removal.
{"title":"EFFICACY OF MORINDA CITRIFOLIA ASSOCIATED WITH MANUAL DYNAMIC AGITATION ON SMEAR LAYER REMOVAL: (IN VITRO SCANNING ELECTRON MICROSCOPIC STUDY)","authors":"Ahmed Amin, Nayera A. Mokhless, Mahmoud Aboelseoud","doi":"10.21608/adjalexu.2022.157860.1308","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.157860.1308","url":null,"abstract":"INTRODUCTION: Endodontic treatment requires chemo-mechanical preparation of root canal to minimize the intracanal bacterial load. However, mechanical debridement results in smear layer formation containing infected debris requiring its removal before obturation. AIM OF THE STUDY: To assess the efficacy of Morinda Citrifolia juice (MCJ) as final irrigation protocol associated with manual dynamic agitation on smear layer removal by using scanning electron microscope. MATERIALS AND METHODS: Forty-five human mandibular permanent premolar teeth with single canals were decoronated to a standard length of 15mm and instrumented using ProTaper Next rotary files (X3). Roots were divided into 3 equal groups (n=15) according to the final irrigant used: Group I: 6% MCJ, Group II: 6% MCJ + 17% EDTA, Group III (control group): 2.5% NaOCl + 17% EDTA. Manual dynamic agitation (MDA) was used to activate the irrigants in all groups. Teeth were then prepared for scanning electron microscopy evaluation, and smear layer removal was assessed.. Comparisons between the study groups were done using Kruskal Wallis test, while comparisons of different regions within each group were done using Friedman test. RESULTS: Along complete canal length, no significant difference was found between 6%MCJ+17% EDTA and 2.5% NaOCl + 17% EDTA (p=0.29). However, a significant difference was noted between 6%MCJ and 2.5% NaOCl + 17% EDTA (p=0.001). In all groups, the coronal third showed the best results (P = 0.02) and the apical third showed the worst (P = 0.007). CONCLUSION: The use of 6%MCJ+17% EDTA associated with MDA could be an alternative to 2.5% NaOCl + 17% EDTA for smear layer removal, however, MCJ alone isn’t effective in smear layer removal.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2023.249332.1446
Rodaina H. Helmy, Pansai Mohamed, Yomna Ibrahim, Mai Eldokmak, Eman Sedek, Amal El-Naggar, Aya Abdelkarim
BACKGROUND: Dental caries is considered the most prevalent oral disease, especially among children. Full coverage is indicated in multi-surface carious lesions, large interproximal lesions, teeth with hypoplastic defects, or severe discolorations, and cases with very poor oral hygiene and high caries risk. Pulp therapy procedures should be followed by the addition of a full coverage restoration to provide support to the tooth structure. There are various materials and methods of fabrication of full coverage primary crowns. OBJECTIVES: This review classifies pediatric crowns according to the method of fabrication. Each category is then subclassified according to material. CONCLUSION: The most suitable crown should be chosen based on the patient cooperation, esthetic demands, extent of decay, amount of tooth structure as well as moisture control and ability of bonding to the tooth.
{"title":"A Dental Materials Approach to Pediatric Dental Full Coverage – A Review","authors":"Rodaina H. Helmy, Pansai Mohamed, Yomna Ibrahim, Mai Eldokmak, Eman Sedek, Amal El-Naggar, Aya Abdelkarim","doi":"10.21608/adjalexu.2023.249332.1446","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.249332.1446","url":null,"abstract":"BACKGROUND: Dental caries is considered the most prevalent oral disease, especially among children. Full coverage is indicated in multi-surface carious lesions, large interproximal lesions, teeth with hypoplastic defects, or severe discolorations, and cases with very poor oral hygiene and high caries risk. Pulp therapy procedures should be followed by the addition of a full coverage restoration to provide support to the tooth structure. There are various materials and methods of fabrication of full coverage primary crowns. OBJECTIVES: This review classifies pediatric crowns according to the method of fabrication. Each category is then subclassified according to material. CONCLUSION: The most suitable crown should be chosen based on the patient cooperation, esthetic demands, extent of decay, amount of tooth structure as well as moisture control and ability of bonding to the tooth.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"124 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138609167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.146114.1290
Mohamed Abo-El-Saad, S. Ayad, Lydia F. Melek, Hagar Abdel Fattah
INTRODUCTION :"After extracting teeth, both remarkable resorption in the alveolar bone and an obvious reduction have occurred in the labial bone plate as a consequence of the blood supply deficiency that happens especially when the periodontal ligaments are lost. Therefore, to keep the periodontal ligaments preserved, a socket shield technique with autogenous dentine was introduced. AIM OF THIS STUDY: Radiographic evaluation of a combined technique using autogenous dentin graft with socket shield for pre-implant socket preservation Patient and method: Eight patients received socket preservation using alloplast with socket shield on one side and received socket preservation using Autogenous dentin graft with socket shield on the contralateral side (split-mouth Design). CBCT was done before surgery and after 3 months to evaluate bone density and bone height . RESULT: The density of the recently formed teeth bone was significantly greater in the study group participants (P=0.011) than in the control one. However, when comparing its height among the 2 groups, there was no significant difference that could be considered. CONCLUSION: Autogenous Dentin proved to be a promising graft together with using the socket shield protection approach that helped in preserving the socket, especially in the esthetic zone. Therefore, further clinical studies could be performed to compare autogenous dentin and other bone substitutes.
{"title":"COMPARISON OF SOCKET PRESERVATION USING SOCKET SHIELD TECHNIQUE WITH AUTOGENOUS DENTIN GRAFT VERSUS ALLOPLAST GRAFT MATERIAL (CLINICAL STUDY)","authors":"Mohamed Abo-El-Saad, S. Ayad, Lydia F. Melek, Hagar Abdel Fattah","doi":"10.21608/adjalexu.2022.146114.1290","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.146114.1290","url":null,"abstract":"INTRODUCTION :\"After extracting teeth, both remarkable resorption in the alveolar bone and an obvious reduction have occurred in the labial bone plate as a consequence of the blood supply deficiency that happens especially when the periodontal ligaments are lost. Therefore, to keep the periodontal ligaments preserved, a socket shield technique with autogenous dentine was introduced. AIM OF THIS STUDY: Radiographic evaluation of a combined technique using autogenous dentin graft with socket shield for pre-implant socket preservation Patient and method: Eight patients received socket preservation using alloplast with socket shield on one side and received socket preservation using Autogenous dentin graft with socket shield on the contralateral side (split-mouth Design). CBCT was done before surgery and after 3 months to evaluate bone density and bone height . RESULT: The density of the recently formed teeth bone was significantly greater in the study group participants (P=0.011) than in the control one. However, when comparing its height among the 2 groups, there was no significant difference that could be considered. CONCLUSION: Autogenous Dentin proved to be a promising graft together with using the socket shield protection approach that helped in preserving the socket, especially in the esthetic zone. Therefore, further clinical studies could be performed to compare autogenous dentin and other bone substitutes.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138619790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.154450.1305
Nourhan Soliman, Amal El-Hak, Azza S. Koura, Nihal Elkazzaz, Mounir El-Adway
INTRODUCTION: Lead poisoning is a threat to public health due to its permanent health consequences. Since antioxidant integration is considered as the most effective therapy sesame oil has been recommended for preventing lead-induced poisoning. The purpose of this research is to examine the ultrastructural changes that may develop in the acini and duct system of the parotid salivary glands of adult albino rats after exposure to lead acetate, and to identify the possible protective effect of sesame oil. MATERIALS AND METHODS: This research included 24 adult male albino rats weighing between 180-200g. Randomly, the rats were separated into three equal groups: Group I (Control), Group II (Lead acetate), and Group III (Lead acetate + Sesame oil). After five weeks of experimentation, blood was drawn and tested using atomic absorption spectroscopy (AAS) to determine the blood lead level. After euthanization, glands were dissected for transmission electron microscopy analysis. RESULTS: Group (II) blood results demonstrated a rise in blood lead levels, but group (III) blood lead levels were midway between groups (I) and (II), demonstrating the therapeutic impact of sesame oil. Group (II) revealed acinar cells with evidence of cytotoxicity, including degenerated mitochondria, apoptotic nuclei, whereas the ducts had lumens with stagnant secretion. The ultrastructure of their acinar cells and duct system improved significantly in group III. CONCLUSIONS: Sesame oil reduced the lead acetate toxicity in rats, which may be utilized as a prophylactic strategy in order to avoid the permanent negative effects of lead acetate exposure.
{"title":"THE PROTECTIVE ROLE OF SESAME OIL ON RAT PAROTID SALIVARY GLANDS SUBJECTED TO LEAD EXPOSURE","authors":"Nourhan Soliman, Amal El-Hak, Azza S. Koura, Nihal Elkazzaz, Mounir El-Adway","doi":"10.21608/adjalexu.2022.154450.1305","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.154450.1305","url":null,"abstract":"INTRODUCTION: Lead poisoning is a threat to public health due to its permanent health consequences. Since antioxidant integration is considered as the most effective therapy sesame oil has been recommended for preventing lead-induced poisoning. The purpose of this research is to examine the ultrastructural changes that may develop in the acini and duct system of the parotid salivary glands of adult albino rats after exposure to lead acetate, and to identify the possible protective effect of sesame oil. MATERIALS AND METHODS: This research included 24 adult male albino rats weighing between 180-200g. Randomly, the rats were separated into three equal groups: Group I (Control), Group II (Lead acetate), and Group III (Lead acetate + Sesame oil). After five weeks of experimentation, blood was drawn and tested using atomic absorption spectroscopy (AAS) to determine the blood lead level. After euthanization, glands were dissected for transmission electron microscopy analysis. RESULTS: Group (II) blood results demonstrated a rise in blood lead levels, but group (III) blood lead levels were midway between groups (I) and (II), demonstrating the therapeutic impact of sesame oil. Group (II) revealed acinar cells with evidence of cytotoxicity, including degenerated mitochondria, apoptotic nuclei, whereas the ducts had lumens with stagnant secretion. The ultrastructure of their acinar cells and duct system improved significantly in group III. CONCLUSIONS: Sesame oil reduced the lead acetate toxicity in rats, which may be utilized as a prophylactic strategy in order to avoid the permanent negative effects of lead acetate exposure.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138611765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.150273.1296
Marwa Mohamed, Riham Fliefel, Ahmed Shaaban
INTRODUCTION: Dental implants have lately emerged as a feasible therapeutic alternative for replacing missing teeth. Implants have undergone continuous improvement to increase their functionality and longevity to meet patients' needs for shorter treatment periods and the need to deal with increasingly complex clinical situations. Surface modifications have been the focus of continuous improvement in modern implants, guiding a new era of surface treatment with chemically modified hydrophilic surfaces. OBJECTIVES: To evaluate the impact of "Hydrophilic Surface Implants (HSI)" on osseointegration in comparison to "Nonhydrophilic Surface Implants (NSI) in the mandibular posterior area. Methodology: This randomized controlled clinical trial was executed on twelve patients with missing mandibular posterior teeth, randomly allocated into two groups. Group I: six patients received hydrophilic dental implants (HSI), while Group II: six patients received "Nonhydrophilic Surface Implants (NSI). Implant stability, bone density, marginal bone loss, and biochemical analysis of bone formation using Runt-related transcription factor 2 (RUNX2) were all assessed for both groups. RESULTS: There were no significant differences between the two groups concerning implant stability (P=0.381), bone density around the implants (P=0.326), marginal bone loss around the implants (P=0.416), or biomarkers of bone formation (RUNX2) (P=0.828) along the course of the clinical trial. CONCLUSION: The Hydrophilic Surface Implants (HSI)) showed better results compared to Nonhydrophilic Surface Implants (NSI) in all investigated parameters, although the difference was not statistically
{"title":"THE EFFECT OF SURFACE TREATMENT OF THE DENTAL IMPLANT ON THE SEOINTEGRATION IN MANDIBULAR POSTERIOR MISSING TEETH: A RANDOMIZED CONTROLLED CLINICAL TRIAL","authors":"Marwa Mohamed, Riham Fliefel, Ahmed Shaaban","doi":"10.21608/adjalexu.2022.150273.1296","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.150273.1296","url":null,"abstract":"INTRODUCTION: Dental implants have lately emerged as a feasible therapeutic alternative for replacing missing teeth. Implants have undergone continuous improvement to increase their functionality and longevity to meet patients' needs for shorter treatment periods and the need to deal with increasingly complex clinical situations. Surface modifications have been the focus of continuous improvement in modern implants, guiding a new era of surface treatment with chemically modified hydrophilic surfaces. OBJECTIVES: To evaluate the impact of \"Hydrophilic Surface Implants (HSI)\" on osseointegration in comparison to \"Nonhydrophilic Surface Implants (NSI) in the mandibular posterior area. Methodology: This randomized controlled clinical trial was executed on twelve patients with missing mandibular posterior teeth, randomly allocated into two groups. Group I: six patients received hydrophilic dental implants (HSI), while Group II: six patients received \"Nonhydrophilic Surface Implants (NSI). Implant stability, bone density, marginal bone loss, and biochemical analysis of bone formation using Runt-related transcription factor 2 (RUNX2) were all assessed for both groups. RESULTS: There were no significant differences between the two groups concerning implant stability (P=0.381), bone density around the implants (P=0.326), marginal bone loss around the implants (P=0.416), or biomarkers of bone formation (RUNX2) (P=0.828) along the course of the clinical trial. CONCLUSION: The Hydrophilic Surface Implants (HSI)) showed better results compared to Nonhydrophilic Surface Implants (NSI) in all investigated parameters, although the difference was not statistically","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 82","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.156915.1307
Mohamed Abdulaal aldeeb, Mervat M. Khalil, Nesma Khalil, Tasneem Amer
INTRODUCTION: Enhancing the survival rate of fat grafts is still a challenging issue. Therefore, the introduction of additives such as Botulinum Toxin (BoNTA) to promote fat graft survival was taken into consideration and initially assessed in a rabbit model. Aim of the study: Is to evaluate histologically and histomorphometrically the effect of BoNTA on the survival rate of fat graft. MATERIALS AND METHODS: We used 15 rabbits in each group. Each rabbit had two incision lines made in its lips as recipient sites, and fat tissue was extracted from the donor site—the scapular adipose sacs—by cutting those incision lines. There were two sets of lips on each of the rabbits: one set was for the control group, and the other study group. The control group merely received a fat transplant with 0.5ml of saline, while the experimental group received a fat graft with 5 units of BoNTA. Five rabbits were scarified at the 3, 6, and 9-week postoperative testing intervals. The upper lip was dissected for a light microscopic analysis and histomorphometrical investigation. RESULTS: Histological evaluation showed that injection with BoNTA improved survival rate and vascularization of fat graft. In comparison to the control group, the study group's percentage of the surface area of the fat graft rose statistically significantly at 3, 6 and 9 weeks (P <0.001), according to histomorphometrical analysis. CONCLUSION: The current experimental investigation implies that pre-transplantation treatment with BoNTA can enhance the integrity and angiogenesis of fat graft.
{"title":"EFFECT OF THE BOTULINUM TOXIN ON SURVIVAL RATE OF FAT TISSUE GRAFT (AN EXPERIMENTAL STUDY)","authors":"Mohamed Abdulaal aldeeb, Mervat M. Khalil, Nesma Khalil, Tasneem Amer","doi":"10.21608/adjalexu.2022.156915.1307","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.156915.1307","url":null,"abstract":"INTRODUCTION: Enhancing the survival rate of fat grafts is still a challenging issue. Therefore, the introduction of additives such as Botulinum Toxin (BoNTA) to promote fat graft survival was taken into consideration and initially assessed in a rabbit model. Aim of the study: Is to evaluate histologically and histomorphometrically the effect of BoNTA on the survival rate of fat graft. MATERIALS AND METHODS: We used 15 rabbits in each group. Each rabbit had two incision lines made in its lips as recipient sites, and fat tissue was extracted from the donor site—the scapular adipose sacs—by cutting those incision lines. There were two sets of lips on each of the rabbits: one set was for the control group, and the other study group. The control group merely received a fat transplant with 0.5ml of saline, while the experimental group received a fat graft with 5 units of BoNTA. Five rabbits were scarified at the 3, 6, and 9-week postoperative testing intervals. The upper lip was dissected for a light microscopic analysis and histomorphometrical investigation. RESULTS: Histological evaluation showed that injection with BoNTA improved survival rate and vascularization of fat graft. In comparison to the control group, the study group's percentage of the surface area of the fat graft rose statistically significantly at 3, 6 and 9 weeks (P <0.001), according to histomorphometrical analysis. CONCLUSION: The current experimental investigation implies that pre-transplantation treatment with BoNTA can enhance the integrity and angiogenesis of fat graft.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138614878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2022.150446.1297
Ahmed Awaad, Akram Neena, Faten Abbas
INTRODUCTION: Splinting of multiple implants during impression with the most accurate material to reproduce their intraoral relationship is deemed necessary for achieving passively fitting prosthesis. OBJECTIVES: To assess positional accuracy of multiimplant impressions for completely edentulous arches obtained by a 3D printed splint and compare the results obtained with those obtained with conventional methods. MATERIAL AND METHODS. One mandibular epoxy model with 4 parallel implants was used as master reference model. A total of 24 (n=24) open tray impressions were done using a custom-made tray and were poured in dental stone. Eight impressions were done with 3D printed splint (group I), 8 were done with the conventional splinting method (group II), and 8 were done with sectional splinting method (group III). Four impression posts were attached to each cast, and all casts were scanned using a desktop scanner. Surface scans for the 3 groups were superimposed with the scan of the master reference model. The positional accuracy of each post was compared with the reference model to assess positional deviations. RESULTS: Models of group I showed lower positional deviation compared to other groups. No statistically significant differences were found between the 3 impression techniques regarding positional accuracy of the implants. CONCLUSIONS: 3D printed splint method can be used as an alternative to conventional splinting techniques.
{"title":"Digital assessment of positional accuracy of different splinting multiimplant impression techniques: An in vitro comparative study","authors":"Ahmed Awaad, Akram Neena, Faten Abbas","doi":"10.21608/adjalexu.2022.150446.1297","DOIUrl":"https://doi.org/10.21608/adjalexu.2022.150446.1297","url":null,"abstract":"INTRODUCTION: Splinting of multiple implants during impression with the most accurate material to reproduce their intraoral relationship is deemed necessary for achieving passively fitting prosthesis. OBJECTIVES: To assess positional accuracy of multiimplant impressions for completely edentulous arches obtained by a 3D printed splint and compare the results obtained with those obtained with conventional methods. MATERIAL AND METHODS. One mandibular epoxy model with 4 parallel implants was used as master reference model. A total of 24 (n=24) open tray impressions were done using a custom-made tray and were poured in dental stone. Eight impressions were done with 3D printed splint (group I), 8 were done with the conventional splinting method (group II), and 8 were done with sectional splinting method (group III). Four impression posts were attached to each cast, and all casts were scanned using a desktop scanner. Surface scans for the 3 groups were superimposed with the scan of the master reference model. The positional accuracy of each post was compared with the reference model to assess positional deviations. RESULTS: Models of group I showed lower positional deviation compared to other groups. No statistically significant differences were found between the 3 impression techniques regarding positional accuracy of the implants. CONCLUSIONS: 3D printed splint method can be used as an alternative to conventional splinting techniques.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 53","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Radiographs taken intra-orally are essential for planning a diagnosis; however the resulting two-dimensional images require thorough interpretation. Cone beam computed Tomographic (CBCT) imaging offers a more precise, three-dimensional image that could aid in proper diagnosis and treatment planning in endodontic and endo-periodontal cases. OBJECTIVES: Assessment of CBCT referral reasons to private radiology centers, and its impact on modifying treatment plan in endodontic and endo-periodontal related cases. MATERIALS AND METHODS: This cross-sectional study comprised a total of 131 patients, who visited private radiology centers in Alexandria, seeking CBCT scans, from July 2021to June 2022: All scans were inspected for assessing referral reasons; referring dentists were asked about their reason for CBCT acquisition, and its effect on their diagnosis and treatment plan. Assessed cases were categorized into either a group of teeth with solitary endodontic-related problem or teeth with an endodontic-periodontal - related problem. RESULTS: The number of teeth found with endo-periodontal radiographic problems in the CBCT scans was significantly lower than solitary endodontic cases (n=14, 8.4%,n=152, 91.5% respectively). Also, a significant difference was detected between those referred cases with endodontic-Periodontal lesions that were not previously root canal treated and those endodontic related cases that received earlier endodontic treatment (p=0.004*) , CBCT had a positive effect on changing the endodontists’ diagnosis and treatment plan, especially in endodontic-periodontal cases (p<0.01 ٭ ). CONCLUSION: CBCT is considered crucial for detection and proper diagnosis of endo-perio lesions. For all endodontic cases with missed canals, calcified canals and inflammatory resorptive defects
{"title":"ASSESSMENT OF CONE BEAM COMPUTED TOMOGRAPHY SCANS REFERRAL REASONS AND ITS IMPACT ON MODIFYING TREATMENT PLAN IN ENDODONTICS","authors":"Shereen Elsaid, Hassan Abouelkheir, Rania Fahmy, Salma Genena","doi":"10.21608/adjalexu.2023.169349.1322","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.169349.1322","url":null,"abstract":"BACKGROUND: Radiographs taken intra-orally are essential for planning a diagnosis; however the resulting two-dimensional images require thorough interpretation. Cone beam computed Tomographic (CBCT) imaging offers a more precise, three-dimensional image that could aid in proper diagnosis and treatment planning in endodontic and endo-periodontal cases. OBJECTIVES: Assessment of CBCT referral reasons to private radiology centers, and its impact on modifying treatment plan in endodontic and endo-periodontal related cases. MATERIALS AND METHODS: This cross-sectional study comprised a total of 131 patients, who visited private radiology centers in Alexandria, seeking CBCT scans, from July 2021to June 2022: All scans were inspected for assessing referral reasons; referring dentists were asked about their reason for CBCT acquisition, and its effect on their diagnosis and treatment plan. Assessed cases were categorized into either a group of teeth with solitary endodontic-related problem or teeth with an endodontic-periodontal - related problem. RESULTS: The number of teeth found with endo-periodontal radiographic problems in the CBCT scans was significantly lower than solitary endodontic cases (n=14, 8.4%,n=152, 91.5% respectively). Also, a significant difference was detected between those referred cases with endodontic-Periodontal lesions that were not previously root canal treated and those endodontic related cases that received earlier endodontic treatment (p=0.004*) , CBCT had a positive effect on changing the endodontists’ diagnosis and treatment plan, especially in endodontic-periodontal cases (p<0.01 ٭ ). CONCLUSION: CBCT is considered crucial for detection and proper diagnosis of endo-perio lesions. For all endodontic cases with missed canals, calcified canals and inflammatory resorptive defects","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.21608/adjalexu.2023.176994.1328
Dina W. Eldeeb, Ahmed M. A. Hommos, Maha Talaab, Samia Soliman
INTRODUCTION: proper management of furcation involvements has always been a demanding issue in periodontal therapy. Herbal medicine is nowadays proposed to provide novel alternative approaches for restoring defective bone. A Chinese herb known as Angelica sinensis (As) has various pharmacological effects as it promotes proliferation and differentiation of osteoblasts OBJECTIVES: The aim of this study was to evaluate the effectiveness of Angelica sinensis in conjunction with β -tricalcium phosphate in the management of class II furcation defects in dogs MATERIALS AND METHODS: This randomized study was carried on 6 clinically healthy mongrel dogs. 24 grade II critical-sized furcation defects were surgically created in the mandibular third and fourth premolars. 12 defects were filled with Beta-tricalcium phosphate (β -TCP) bone gr aft only (control group). While in the other 12 defects β -TCP was mixed with Angelica sinensis powder (experimental group). The defects were covered by collagen membrane, The dogs were sacrificed at 4 and 8 weeks postoperative. RESULTS: The histological analysis has revealed better regenerative features regarding alveolar bone, periodontal ligament and cementum in the experimental groups when compared to control groups. CONCLUSIONS: Angelica sinensis herb could enhance the periodontal regenerative potential of β -TCP bone graft.
{"title":"HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY)","authors":"Dina W. Eldeeb, Ahmed M. A. Hommos, Maha Talaab, Samia Soliman","doi":"10.21608/adjalexu.2023.176994.1328","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.176994.1328","url":null,"abstract":"INTRODUCTION: proper management of furcation involvements has always been a demanding issue in periodontal therapy. Herbal medicine is nowadays proposed to provide novel alternative approaches for restoring defective bone. A Chinese herb known as Angelica sinensis (As) has various pharmacological effects as it promotes proliferation and differentiation of osteoblasts OBJECTIVES: The aim of this study was to evaluate the effectiveness of Angelica sinensis in conjunction with β -tricalcium phosphate in the management of class II furcation defects in dogs MATERIALS AND METHODS: This randomized study was carried on 6 clinically healthy mongrel dogs. 24 grade II critical-sized furcation defects were surgically created in the mandibular third and fourth premolars. 12 defects were filled with Beta-tricalcium phosphate (β -TCP) bone gr aft only (control group). While in the other 12 defects β -TCP was mixed with Angelica sinensis powder (experimental group). The defects were covered by collagen membrane, The dogs were sacrificed at 4 and 8 weeks postoperative. RESULTS: The histological analysis has revealed better regenerative features regarding alveolar bone, periodontal ligament and cementum in the experimental groups when compared to control groups. CONCLUSIONS: Angelica sinensis herb could enhance the periodontal regenerative potential of β -TCP bone graft.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"11 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138609697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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