Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2024.213360.1381
Wael Nomeir, Mervat M. Khalil, Ahmed O. Sweedan, Hend Helmy
BACKGROUND: Biopsies may be difficult to do if the lesions are too small, too near to vital tissues, or too tough to access. Examples include excision and incision, fine needle (with or without US guidance), core biopsy (with or without US guidance), and other traditional biopsy procedures. OBJECTIVES: To evaluate the efficacy of the 3D printed tooth-supported stent in biopsy for intra-bony lesions. MATERIALS AND METHODS: 12 individuals with intra-bony lesions in the jaw. All participants were recruited at random from the Oral and Maxillofacial Surgery outpatient clinic at the University of Alexandria's School of Dentistry. The sample size was calculated by G Power, version 3.1.9.2 with the following criteria: 80% study power and 5% alpha error. The sample size was determined to be 6 patients per group based on the difference between two independent means using pooled SD=0.48 mm to account for missing follow-up cases. Biopsies were obtained using a surgical guide and a trephine bur, and the findings were examined by Cone beam computed tomography (CBCT) following the surgery. RESULTS: The planning software and the related (digitally created) biopsy cylinder were used to test the precision of the postoperative low-dose CBCT. The horizontal angle of departure between a drill's virtually planned location and its actual placement ranged from 0.38 degrees to 0.95 degrees, with a mean of 0.70 degrees and a standard deviation of 0.18 degrees. CONCLUSION: Template-guided biopsy of the jawbone seems to be an alternative to a conventional approach with possibility of obtaining predictable and safe biopsies with comparatively low invasiveness and risk.
背景：如果病变太小、太靠近重要组织或太难进入，活检可能很难进行。例如，切除和切开、细针（有或没有 US 引导）、核心活检（有或没有 US 引导）以及其他传统活检程序。目的评估 3D 打印牙齿支撑支架在骨内病变活检中的功效。材料与方法：12 名颌骨内病变患者。所有参与者均从亚历山大大学牙科学院口腔颌面外科门诊随机招募。样本量由 G Power（3.1.9.2 版）按照以下标准计算得出：研究功率为 80%，α误差为 5%。根据两个独立平均值之间的差值确定每组样本量为 6 名患者，考虑到随访病例的缺失，汇总的 SD=0.48 mm。使用手术导板和穿刺针进行活检，术后通过锥形束计算机断层扫描（CBCT）检查结果。结果：规划软件和相关（数字创建）活检筒用于测试术后低剂量 CBCT 的精确度。钻头的虚拟计划位置与实际位置之间的水平偏离角度从 0.38 度到 0.95 度不等，平均值为 0.70 度，标准偏差为 0.18 度。结论：模板引导下的颌骨活检似乎是传统方法的一种替代方法，可获得可预测和安全的活检结果，创伤和风险相对较低。
{"title":"EVALUATION OF 3D PRINTED STENTS FOR GUIDED INTRABONY MAXILLOFACIAL BIOPSIES","authors":"Wael Nomeir, Mervat M. Khalil, Ahmed O. Sweedan, Hend Helmy","doi":"10.21608/adjalexu.2024.213360.1381","DOIUrl":"https://doi.org/10.21608/adjalexu.2024.213360.1381","url":null,"abstract":"BACKGROUND: Biopsies may be difficult to do if the lesions are too small, too near to vital tissues, or too tough to access. Examples include excision and incision, fine needle (with or without US guidance), core biopsy (with or without US guidance), and other traditional biopsy procedures. OBJECTIVES: To evaluate the efficacy of the 3D printed tooth-supported stent in biopsy for intra-bony lesions. MATERIALS AND METHODS: 12 individuals with intra-bony lesions in the jaw. All participants were recruited at random from the Oral and Maxillofacial Surgery outpatient clinic at the University of Alexandria's School of Dentistry. The sample size was calculated by G Power, version 3.1.9.2 with the following criteria: 80% study power and 5% alpha error. The sample size was determined to be 6 patients per group based on the difference between two independent means using pooled SD=0.48 mm to account for missing follow-up cases. Biopsies were obtained using a surgical guide and a trephine bur, and the findings were examined by Cone beam computed tomography (CBCT) following the surgery. RESULTS: The planning software and the related (digitally created) biopsy cylinder were used to test the precision of the postoperative low-dose CBCT. The horizontal angle of departure between a drill's virtually planned location and its actual placement ranged from 0.38 degrees to 0.95 degrees, with a mean of 0.70 degrees and a standard deviation of 0.18 degrees. CONCLUSION: Template-guided biopsy of the jawbone seems to be an alternative to a conventional approach with possibility of obtaining predictable and safe biopsies with comparatively low invasiveness and risk.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"38 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.208745.1374
Tarek Farfour, Yousria Shalaby, M. Halawani
INTRODUCTION: Occlusal forces are considered a vital aspect of any dental treatment plan. Maximum occlusal force is intended to be correlated with facial dimensions, gender, and race. OBJECTIVES: The purpose of this study was to analyze facial morphology and maximum occlusal bite among Egyptian dental students, in addition to determining the difference between males and females. MATERIAL AND METHODS: Based on gender, 46 dental students were grouped into two distinct groups (23 males and 23 females). Each participant was photographed with a digital camera, and 2D Adobe Photoshop CS5 was utilized to calculate facial morphology according to their magnification ratio. Using a piezoresistive sensor (Flexiforce, Tekscan Inc., South Boston, USA), bite forces on both sides were measured three times. Maximum bite force and average occlusal force were recorded for both sides. RESULTS: The mean value of the maximum occlusal force was 445.2 ± 66.8 N in males and 354.7 ± 81.19 N in females, with a highly significant difference. The majority of facial morphology variables were statistically greater in males than females, which was clarified through the results of the research. However, the correlation between male facial morphology and the bite was statistically significant. CONCLUSIONS: In terms of bite forces and facial morphology, males have higher values for most of the parameters and a significant correlation between them.
{"title":"ANALYSIS OF MAXIMUM BITE FORCE CORRELATING TO FACIAL MORPHOLOGY AMONG EGYPTIAN DENTAL STUDENTS","authors":"Tarek Farfour, Yousria Shalaby, M. Halawani","doi":"10.21608/adjalexu.2023.208745.1374","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.208745.1374","url":null,"abstract":"INTRODUCTION: Occlusal forces are considered a vital aspect of any dental treatment plan. Maximum occlusal force is intended to be correlated with facial dimensions, gender, and race. OBJECTIVES: The purpose of this study was to analyze facial morphology and maximum occlusal bite among Egyptian dental students, in addition to determining the difference between males and females. MATERIAL AND METHODS: Based on gender, 46 dental students were grouped into two distinct groups (23 males and 23 females). Each participant was photographed with a digital camera, and 2D Adobe Photoshop CS5 was utilized to calculate facial morphology according to their magnification ratio. Using a piezoresistive sensor (Flexiforce, Tekscan Inc., South Boston, USA), bite forces on both sides were measured three times. Maximum bite force and average occlusal force were recorded for both sides. RESULTS: The mean value of the maximum occlusal force was 445.2 ± 66.8 N in males and 354.7 ± 81.19 N in females, with a highly significant difference. The majority of facial morphology variables were statistically greater in males than females, which was clarified through the results of the research. However, the correlation between male facial morphology and the bite was statistically significant. CONCLUSIONS: In terms of bite forces and facial morphology, males have higher values for most of the parameters and a significant correlation between them.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"280 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.228447.1409
Abdelrahman Gad, Ragab Hassan, Gaafar El Halawani
INTRODUCTION: In immediate implant placement, Grafting materials should be used if there is a gap of more than 2mm between socket walls and the implant body. Ultra-wide diameter implants (UWD) ''7 - 9 mm diameter " were introduced to allow more engagement to molar socket walls and to reduce the necessity for using bone grafts in immediate molar placement. OBJECTIVES: Evaluation of both radiographical and clinical outcomes of osteointegration and peri-implant bone density outcomes when using UWD implant placed immediately in molar extraction socket. MATERIALS AND METHODS: 12 ultrawide dental implants were placed immediately in freshly atraumatically extracted molar sockets of 12 patients without raising flaps or using bone grafts. Cement retained crown was loaded 6 months postoperatively. All patients underwent clinical and radiographical evaluations for 9 months. RESULTS: Implant stability and peri-implant bone density showed a statistically significant increase through follow-up time periods. CONCLUSION: This study demonstrated that using ultrawide dental implants immediately in freshly extracted mandibular molar sockets is a predictable modality to improve implant stability and bone density with less marginal bone resorption.
{"title":"EVALUATION OF IMMEDIATELY PLACED ULTRA WIDE DIAMETER IMPLANT PLACED IN MANDIBULAR MOLARS (A SINGLE ARM CLINICAL TRIAL)","authors":"Abdelrahman Gad, Ragab Hassan, Gaafar El Halawani","doi":"10.21608/adjalexu.2023.228447.1409","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.228447.1409","url":null,"abstract":"INTRODUCTION: In immediate implant placement, Grafting materials should be used if there is a gap of more than 2mm between socket walls and the implant body. Ultra-wide diameter implants (UWD) ''7 - 9 mm diameter \" were introduced to allow more engagement to molar socket walls and to reduce the necessity for using bone grafts in immediate molar placement. OBJECTIVES: Evaluation of both radiographical and clinical outcomes of osteointegration and peri-implant bone density outcomes when using UWD implant placed immediately in molar extraction socket. MATERIALS AND METHODS: 12 ultrawide dental implants were placed immediately in freshly atraumatically extracted molar sockets of 12 patients without raising flaps or using bone grafts. Cement retained crown was loaded 6 months postoperatively. All patients underwent clinical and radiographical evaluations for 9 months. RESULTS: Implant stability and peri-implant bone density showed a statistically significant increase through follow-up time periods. CONCLUSION: This study demonstrated that using ultrawide dental implants immediately in freshly extracted mandibular molar sockets is a predictable modality to improve implant stability and bone density with less marginal bone resorption.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"226 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Dental implants are considered a highly reasonable method for the replacement of missing teeth and the success of this treatment modality is highly dependent on the bone quality; where the better the quality the more superior the implant osseo-integration. Bone turnover process also plays a fundamental role in implant osseo-integration and can give a prediction of the future implant stability and possible bone loss when its blood markers are assessed. OBJECTIVE: To assess the bone turnover marker (BTM) values and correlate their impact on the condition of the jaw bone in patients having dental implants and to evaluate the density and quality of bone around the implant radiographically in relation to normal and abnormal bone turnover markers. MATERIAL AND METHODS: This study was carried out as a single arm clinical trial. Fifteen male patients who require single tooth replacement in the lower posterior region, whose age range was 30-40 years, underwent blood analysis of bone turnover markers; bone alkaline phosphatase and osteocalcin, using the technique of ELISA and CBCT examination preoperatively. The bone density was measured in the proposed area of implant placement using Ondemand software. Following implant placement bone density and marginal bone loss were radiographically evaluated 3 and 6 months postoperatively and the results were correlated to the patient’s bone turnover markers values. RESULTS: There was maximum primary stability and successful osseo-integration in all implants, with minor reduction in the bone density before and after the implant placement as well as minor marginal bone loss after 6 months of follow-up, but both were statistically non-significant. There was no significant correlation between marginal bone loss and abnormal bone turnover values. CONCLUSION: Bone turnover markers could not be used to evaluate the bone condition prior to referring to dental implant treatment thus they are not indicators of implant’s osseo-integration
{"title":"EVALUATION OF BONE TURNOVER MARKERS AS INDICATORS FOR OSSEOINTEGRATION OF DENTAL IMPLANTS (A CLINICAL TRIAL)","authors":"Sohaila Hammad, Saeeda Osman, Adham Alashwah, Mona Tahoun","doi":"10.21608/adjalexu.2023.227977.1407","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.227977.1407","url":null,"abstract":"BACKGROUND: Dental implants are considered a highly reasonable method for the replacement of missing teeth and the success of this treatment modality is highly dependent on the bone quality; where the better the quality the more superior the implant osseo-integration. Bone turnover process also plays a fundamental role in implant osseo-integration and can give a prediction of the future implant stability and possible bone loss when its blood markers are assessed. OBJECTIVE: To assess the bone turnover marker (BTM) values and correlate their impact on the condition of the jaw bone in patients having dental implants and to evaluate the density and quality of bone around the implant radiographically in relation to normal and abnormal bone turnover markers. MATERIAL AND METHODS: This study was carried out as a single arm clinical trial. Fifteen male patients who require single tooth replacement in the lower posterior region, whose age range was 30-40 years, underwent blood analysis of bone turnover markers; bone alkaline phosphatase and osteocalcin, using the technique of ELISA and CBCT examination preoperatively. The bone density was measured in the proposed area of implant placement using Ondemand software. Following implant placement bone density and marginal bone loss were radiographically evaluated 3 and 6 months postoperatively and the results were correlated to the patient’s bone turnover markers values. RESULTS: There was maximum primary stability and successful osseo-integration in all implants, with minor reduction in the bone density before and after the implant placement as well as minor marginal bone loss after 6 months of follow-up, but both were statistically non-significant. There was no significant correlation between marginal bone loss and abnormal bone turnover values. CONCLUSION: Bone turnover markers could not be used to evaluate the bone condition prior to referring to dental implant treatment thus they are not indicators of implant’s osseo-integration","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"230 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-05DOI: 10.21608/adjalexu.2023.222675.1397
Abdallah Lulu, Sanaa Abdel kader, Islam M. Abdel Raheem
INTRODUCTION: Endocrown restorations offer a promising alternative to restore endodontically treated teeth. However, various materials are available without being thoroughly evaluated. Purpose: The purpose of the study is to evaluate marginal fit and fracture resistance of endocrown restorations using three CAD-CAM materials. MATERIALS AND METHODS: Eighteen extracted permanent mandibular molars were selected to receive endocrown restoration. Teeth were randomly allocated into three groups based on material type (n=6). (LD): Lithium Disilicate, (FCZ): full contour zirconia, (RNC): resin nanoceramic. All Endocrown restorations were fabricated utilizing CAD-CAM technology. Restorations were adhesively luted to the corresponding prepared teeth and subjected to thermomechanical cycling corresponding to six months of clinical service. Marginal gap was measured before cementation and after cementation and aging using optical microscope. For measuring fracture resistance, samples were loaded till fracture occurs by using Universal Testing Machine. Optical microscope was used to evaluate mode of failure. One-way ANOVA and Tukey's post hoc test were used to analyze fracture resistance, while Two-way ANOVA and Tukey's post hoc test were used to analyze marginal gap. RESULTS: FCZ had the highest fracture load compared to RNC and LD. Zirconia recorded largest microgaps before cementation. CONCLUSION: FCZ showed the highest fracture resistance values. LD and RNC ceramics showed fracture resistance with comparable values recommending their use as endocrown restorations. The tested groups showed marginal fit results within the bounds of clinically acceptable parameters. The material type and artificial aging process had a significant impact on the marginal gap.
{"title":"FRACTURE RESISTANCE AND MARGINAL FIT OF ENDOCROWN RESTORATIONS USING THREE DIFFERENT CAD-CAM MATERIALS","authors":"Abdallah Lulu, Sanaa Abdel kader, Islam M. Abdel Raheem","doi":"10.21608/adjalexu.2023.222675.1397","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.222675.1397","url":null,"abstract":"INTRODUCTION: Endocrown restorations offer a promising alternative to restore endodontically treated teeth. However, various materials are available without being thoroughly evaluated. Purpose: The purpose of the study is to evaluate marginal fit and fracture resistance of endocrown restorations using three CAD-CAM materials. MATERIALS AND METHODS: Eighteen extracted permanent mandibular molars were selected to receive endocrown restoration. Teeth were randomly allocated into three groups based on material type (n=6). (LD): Lithium Disilicate, (FCZ): full contour zirconia, (RNC): resin nanoceramic. All Endocrown restorations were fabricated utilizing CAD-CAM technology. Restorations were adhesively luted to the corresponding prepared teeth and subjected to thermomechanical cycling corresponding to six months of clinical service. Marginal gap was measured before cementation and after cementation and aging using optical microscope. For measuring fracture resistance, samples were loaded till fracture occurs by using Universal Testing Machine. Optical microscope was used to evaluate mode of failure. One-way ANOVA and Tukey's post hoc test were used to analyze fracture resistance, while Two-way ANOVA and Tukey's post hoc test were used to analyze marginal gap. RESULTS: FCZ had the highest fracture load compared to RNC and LD. Zirconia recorded largest microgaps before cementation. CONCLUSION: FCZ showed the highest fracture resistance values. LD and RNC ceramics showed fracture resistance with comparable values recommending their use as endocrown restorations. The tested groups showed marginal fit results within the bounds of clinically acceptable parameters. The material type and artificial aging process had a significant impact on the marginal gap.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"291 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-04DOI: 10.21608/adjalexu.2024.264674.1468
sara Elsayed, Ahmed Abdelrahman, Laila ElHabashy
INTRODUCTION: A combination of Nance and transpalatal arch space maintainers has previously been studied in treatment of Angle’s class II cases. However, this appliance hasn't been the subject of any trials as a space maintainer. AIM: To evaluate the effectiveness of the combined Nance/transpalatal arch (N-TPA) appliance compared to Nance space maintainer in maintaining arch dimensions after bilateral premature loss of maxillary primary molars. MATERIAL AND METHODS: Thirty children with bilateral premature loss of maxillary primary molars were randomly allocated into two groups (n=15). The test group received the N-TPA appliance, and the control group received the Nance appliance. Baseline measurements including arch circumference, intermolar width and arch depth were recorded. Participants were followed up to 9 months for re-evaluation. RESULTS: No statistical significance was found when comparing arch circumference, intermolar width and arch depth. Intra-group comparison of arch depth in the N-TPA group showed a statistical significance at 9 months. Comparison of difference in arch depth measurements from baseline to follow-up time points showed a statistical significance at 6 and 9 months. CONCLUSION: Both appliances provided acceptable space maintenance regarding arch circumference and arch width. Statistical significance was found when comparing arch depth measurements, however, further research is necessary to confirm clinical significance.
{"title":"Effectiveness of combined design nance/transpalatal arch appliance in maintaining arch dimensions after premature extraction of primary molars (A randomized controlled clinical trial)","authors":"sara Elsayed, Ahmed Abdelrahman, Laila ElHabashy","doi":"10.21608/adjalexu.2024.264674.1468","DOIUrl":"https://doi.org/10.21608/adjalexu.2024.264674.1468","url":null,"abstract":"INTRODUCTION: A combination of Nance and transpalatal arch space maintainers has previously been studied in treatment of Angle’s class II cases. However, this appliance hasn't been the subject of any trials as a space maintainer. AIM: To evaluate the effectiveness of the combined Nance/transpalatal arch (N-TPA) appliance compared to Nance space maintainer in maintaining arch dimensions after bilateral premature loss of maxillary primary molars. MATERIAL AND METHODS: Thirty children with bilateral premature loss of maxillary primary molars were randomly allocated into two groups (n=15). The test group received the N-TPA appliance, and the control group received the Nance appliance. Baseline measurements including arch circumference, intermolar width and arch depth were recorded. Participants were followed up to 9 months for re-evaluation. RESULTS: No statistical significance was found when comparing arch circumference, intermolar width and arch depth. Intra-group comparison of arch depth in the N-TPA group showed a statistical significance at 9 months. Comparison of difference in arch depth measurements from baseline to follow-up time points showed a statistical significance at 6 and 9 months. CONCLUSION: Both appliances provided acceptable space maintenance regarding arch circumference and arch width. Statistical significance was found when comparing arch depth measurements, however, further research is necessary to confirm clinical significance.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"6 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141014071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.21608/adjalexu.2024.265307.1472
radwa dawood, A. Hanno, Nadia Wahba, sawsan mahmoud
INTRODUCTION: Children are frequently subjected to liquid medications, especially antibiotics. They are acidic, have low pH and high titratable acidity. This can erode enamel. AIM: This in vitro study aim to determine the correlation between antibiotics as regards their erosive effect and frequency of intake on primary enamel integrity. MATERIALS AND METHODS: Three commonly prescribed pediatric antibiotics groups: macrolides, cephalosporins and mixed composition were chosen. pH and titratable acidity of the selected antibiotics and artificial saliva were determined. Seventy seven human primary teeth, exfoliated or extracted for orthodontic reasons were randomly assigned to three antibiotics groups and a control group, 11specimens for each group. Specimens were immersed in fresh solutions of antibiotics for 1 minute over 3, 5and 10 days, depending on the type of antibiotic. All samples were preserved in artificial saliva in between immersion cycles. Enamel micro hardness was evaluated at baseline, 3& 5&10 days. RESULTS: Highest percent reduction was recorded for the mixed antibiotic (24.39 ±4.65) P<0.0001, followed by cephalosporin (13 .79 ±4.37) P<0.0001 and macrolides (7.99 ±2.82) P<0.0001. Mixed type immersed for 10 days showed the highest reduction in microhardness (37.00 ±4.71). Macrolides for 3 days showed the lowest reduction (12.22 ±3.20). All the experimental groups recorded loss in microhardness with high significant difference P<0.0001. CONCLUSION: Tested antibiotics could erode enamel even when pH is above critical and low titratable acidity. Increasing duration and frequency of prescription, increases the erosive potential.
{"title":"AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY","authors":"radwa dawood, A. Hanno, Nadia Wahba, sawsan mahmoud","doi":"10.21608/adjalexu.2024.265307.1472","DOIUrl":"https://doi.org/10.21608/adjalexu.2024.265307.1472","url":null,"abstract":"INTRODUCTION: Children are frequently subjected to liquid medications, especially antibiotics. They are acidic, have low pH and high titratable acidity. This can erode enamel. AIM: This in vitro study aim to determine the correlation between antibiotics as regards their erosive effect and frequency of intake on primary enamel integrity. MATERIALS AND METHODS: Three commonly prescribed pediatric antibiotics groups: macrolides, cephalosporins and mixed composition were chosen. pH and titratable acidity of the selected antibiotics and artificial saliva were determined. Seventy seven human primary teeth, exfoliated or extracted for orthodontic reasons were randomly assigned to three antibiotics groups and a control group, 11specimens for each group. Specimens were immersed in fresh solutions of antibiotics for 1 minute over 3, 5and 10 days, depending on the type of antibiotic. All samples were preserved in artificial saliva in between immersion cycles. Enamel micro hardness was evaluated at baseline, 3& 5&10 days. RESULTS: Highest percent reduction was recorded for the mixed antibiotic (24.39 ±4.65) P<0.0001, followed by cephalosporin (13 .79 ±4.37) P<0.0001 and macrolides (7.99 ±2.82) P<0.0001. Mixed type immersed for 10 days showed the highest reduction in microhardness (37.00 ±4.71). Macrolides for 3 days showed the lowest reduction (12.22 ±3.20). All the experimental groups recorded loss in microhardness with high significant difference P<0.0001. CONCLUSION: Tested antibiotics could erode enamel even when pH is above critical and low titratable acidity. Increasing duration and frequency of prescription, increases the erosive potential.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"47 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-14DOI: 10.21608/adjalexu.2023.186043.1336
Doaa Abd El-Gawad, Nevien Mohamed, Hanaa Raslan, Noha Dessoky
INTRODUCTION: The process of wound healing is complicated. Despite research, hypertrophic scars still occur and can pose functional and aesthetic issues. Improvement for hypertrophic scars has been attained using a variety of treatment modalities. The strain from the underlying muscles working on the wound edge throughout the healing process is a critical factor in shaping the scar's final appearance. Since botulinum toxin type A (BTA) causes total muscle paralysis, it was suggested as a possible treatment. OBJECTIVES: To evaluate the effect of BTA injection on the final appearance of the surgical scar. MATERIALS AND METHODS: Thirty-six mature male New Zealand rabbits weighing 3.5–4 kg were studied experimentally (one year of age). They were divided into two groups: One received BTA injections into the cheek muscles surrounding a Y-shaped surgical incision. The other group received no further treatment after the incision. A follow-up was performed after 2, 4, and 6 weeks for the assessment of the scar parameters (wound width and Vancouver scar scale (VSS), along with clinical photographs). After each period, the sacrifice group of rabbits was done. Samples were prepared for histological and histomorphometric analysis by being dissected. RESULTS: When compared to the control group, the BTA-treated group showed an improvement in the appearance of scars, VSS and a reduced increase in wound width. Histological and histomorphometric results indicate that the BTA group had a better layout and less collagen deposition than the control group. CONCLUSIONS: BTA injection effectively reduced collagen fibril production and improved hypertrophic scar appearance.
简介：伤口愈合的过程是复杂的。尽管进行了大量研究，但增生性疤痕仍时有发生，并可能带来功能和美观方面的问题。增生性疤痕已通过多种治疗方式得到改善。在整个愈合过程中，下层肌肉对伤口边缘的压力是形成疤痕最终外观的关键因素。由于 A 型肉毒毒素 (BTA) 会导致肌肉完全麻痹，因此建议将其作为一种可能的治疗方法。目的评估注射 BTA 对手术疤痕最终外观的影响。材料与方法：对 36 只体重为 3.5-4 千克的成熟雄性新西兰兔（一岁）进行实验研究。它们被分为两组：一组在 Y 形手术切口周围的脸颊肌肉注射 BTA。另一组在切口后不再接受任何治疗。2周、4周和6周后进行随访，评估疤痕参数（伤口宽度、温哥华疤痕评分（VSS）以及临床照片）。每个阶段结束后，对兔子进行牺牲分组。将样本剖开，准备进行组织学和组织形态计量学分析。结果：与对照组相比，BTA 治疗组的疤痕外观和 VSS 均有所改善，伤口宽度的增加也有所减少。组织学和组织形态计量学结果表明，与对照组相比，BTA 组的布局更好，胶原沉积更少。结论：注射 BTA 能有效减少胶原纤维的生成，改善增生性疤痕的外观。
{"title":"EFFECT OF BOTULINUM TOXIN ON SURGICAL WOUND HEALING AND SCAR FORMATION (AN EXPERIMENTAL STUDY)","authors":"Doaa Abd El-Gawad, Nevien Mohamed, Hanaa Raslan, Noha Dessoky","doi":"10.21608/adjalexu.2023.186043.1336","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.186043.1336","url":null,"abstract":"INTRODUCTION: The process of wound healing is complicated. Despite research, hypertrophic scars still occur and can pose functional and aesthetic issues. Improvement for hypertrophic scars has been attained using a variety of treatment modalities. The strain from the underlying muscles working on the wound edge throughout the healing process is a critical factor in shaping the scar's final appearance. Since botulinum toxin type A (BTA) causes total muscle paralysis, it was suggested as a possible treatment. OBJECTIVES: To evaluate the effect of BTA injection on the final appearance of the surgical scar. MATERIALS AND METHODS: Thirty-six mature male New Zealand rabbits weighing 3.5–4 kg were studied experimentally (one year of age). They were divided into two groups: One received BTA injections into the cheek muscles surrounding a Y-shaped surgical incision. The other group received no further treatment after the incision. A follow-up was performed after 2, 4, and 6 weeks for the assessment of the scar parameters (wound width and Vancouver scar scale (VSS), along with clinical photographs). After each period, the sacrifice group of rabbits was done. Samples were prepared for histological and histomorphometric analysis by being dissected. RESULTS: When compared to the control group, the BTA-treated group showed an improvement in the appearance of scars, VSS and a reduced increase in wound width. Histological and histomorphometric results indicate that the BTA group had a better layout and less collagen deposition than the control group. CONCLUSIONS: BTA injection effectively reduced collagen fibril production and improved hypertrophic scar appearance.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":" 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140392897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.21608/adjalexu.2023.185369.1333
Mostafa Elashkar, Yehia H. Aboushady, M. Halawani
{"title":"INFLUENCE OF FABRICATION TECHNIQUE ON THE FRACTURE RESISTANCE OF 3-UNIT INTERIM FIXED DENTAL PROSTHESIS: AN IN VITRO STUDY.","authors":"Mostafa Elashkar, Yehia H. Aboushady, M. Halawani","doi":"10.21608/adjalexu.2023.185369.1333","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.185369.1333","url":null,"abstract":"","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"74 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140486398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.21608/adjalexu.2023.197004.1354
Hisham M. Warda, Hassan Abo ElKheir, Maha Taalab
{"title":"A THREE DIMENSIONAL INVITRO STUDY ON THE ACCURACY OF IMPLANT PLACEMENT USING SURGICAL STENTS FABRICATED USING THREE DIFFERENT 3D PRINTERS","authors":"Hisham M. Warda, Hassan Abo ElKheir, Maha Taalab","doi":"10.21608/adjalexu.2023.197004.1354","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.197004.1354","url":null,"abstract":"","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"38 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140489717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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