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EVALUATION OF BONE HEALING BY MESENCHYMAL STEM CELLS IN RABBITS (AN EXPERIMENTAL STUDY) 间充质干细胞对兔子骨愈合的评估(实验研究)
Pub Date : 2024-07-08 DOI: 10.21608/adjalexu.2024.246336.1431
Fadi Fouad Salib, Magda Mohamed Saleh, R. Mehanna, Marwa Essawy, L. Melek
BACKGROUND: Large bone defects are considered a massive challenge in the field of oral and maxillofacial surgery. Cell Therapy using bone marrow-derived mesenchymal stem cells (BM-MSCs), as an alternative technique, has effective potentialfor bone regeneration. AIM OF THE STUDY : To compare histologically the bone healing rate of critical size defects in rabbit tibia using mesenchymal stem cells versus untreated defects. MATERIALS AND METHODS: Critical-sized defects were prepared on the tibia of rabbits. Experimental groups were divided into 2 groups: (a) Control group; untreated rabbits left for spontaneous healing, (b) collagen sponge with MSCs treated group. Sacrificing of rabbitswas done at 2 and 6-week intervals . RESULTS :Bone defects treated with BM-MSCs showed asignificant increase in the healing rate compared to the control group.Histological examination showed immature bone trabeculae lined with plump active osteoblasts with minimal amount of newly formed blood vessels andalmost no inflammatory cell infiltration at the 2-week interval. Furthermore, at the 6-weeks interval the defects were almost healed with mature thickened dense bone trabeculae lined by fattened osteoblasts with no inflammatory infiltration. CONCLUSION: BM-MSCs are a promissing tool for bone regeneration.
背景:大面积骨缺损被认为是口腔颌面外科领域的一项巨大挑战。使用骨髓间充质干细胞(BM-MSCs)进行细胞治疗是一种替代技术,具有有效的骨再生潜力。研究目的:从组织学角度比较使用间充质干细胞与未经处理的兔胫骨临界大小缺损的骨愈合率。材料与方法:在兔子胫骨上制备临界大小的缺损。实验组分为两组:(a) 对照组;未经处理的兔子任其自然愈合;(b) 海绵胶原与间充质干细胞处理组。兔子分别在 2 周和 6 周后处死。结果:与对照组相比,使用间充质干细胞处理的骨缺损愈合率显著提高。组织学检查显示,在间隔 2 周时,未成熟的骨小梁内衬有丰满活跃的成骨细胞,新形成的血管数量极少,几乎没有炎症细胞浸润。此外,间隔 6 周后,缺损基本愈合,骨小梁成熟增厚致密,内衬肥大的成骨细胞,无炎症浸润。结论:BM-间充质干细胞是一种很有前景的骨再生工具。
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引用次数: 0
EVALUATION OF THE STABILITY OF IMMEDIATE IMPLANT PLACEMENT IN MANDIBULAR MOLAR INTER-RADICULAR SEPTUM USING OSSEODENSIFICATION TECHNIQUE (CLINICAL TRIAL) 使用骨增生技术评估下颌磨牙齿间间隔即刻种植体植入的稳定性(临床试验)
Pub Date : 2024-07-08 DOI: 10.21608/adjalexu.2024.241627.1421
Eiman Mohamad Malak, S. Osman, L. Melek
BACKGROUND: Immediate implant placement (IIP) is a valid technique for replacement of badly destructed teeth with fewer surgical procedures and increased levels of patient comfort. OBJECTIVES: To evaluate the stability of immediate implant inserted in mandibular molar inter-radicular septum using osseodensification technique. MATERIALS AND METHODS: Ten patients with ten lower molars to be extracted were chosen according to a list of inclusion and exclusion criteria. The participants undergone atraumatic tooth extraction, then the inter-radicular septum was densified using densah burs, immediate implants were installed, followed by bone graft placement in the gap between the implant and the socket walls, and a healing abutment was placed. Interrupted sutures were then placed around the healing abutment. Assessment included measurements of implant stability using the Osstell device immediatel after implant placement and after 3 months post-operatively. Also, bone density surrounding the implant was measured pre-operatively, immediately post-operatively and after 3 months post-operatively. RESULTS: The results revealed that Secondary Stability (ISQ) three months postoperatively with a mean±SD. of 76.20±5.43 was statistically significantly increased compared to Primary Stability (ISQ) immediately after implant insertion with a mean±SD. of 65.20±4.96( p <0.001). The bone density was significantly increased immediately postoperatively and three months postoperatively compared with preoperatively ( p <0.001, p =0.002; respectively). CONCLUSION: Osseodensification using densah burs was found to be an efficient procedure in increasing stability of immediately placed dental implants in molar inter-radicular septum.
背景:即刻种植体植入(IIP)是一种有效的技术,可用于替换严重破坏的牙齿,手术过程更少,患者更舒适。目的:评估即刻种植体植入牙间隙的稳定性:评估使用骨增量技术将即刻种植体植入下颌磨牙根间隔膜的稳定性。材料和方法:根据纳入和排除标准清单,选择了十名有十颗下臼齿需要拔除的患者。参与者接受创伤性拔牙,然后使用登沙车针对齿间隔膜进行骨质增生,安装即刻种植体,随后在种植体和牙槽骨壁之间的间隙中植入骨移植体,并植入愈合基台。然后在愈合基台周围进行间断缝合。评估包括种植体植入后即刻和术后 3 个月后使用 Osstell 设备测量种植体的稳定性。此外,还对种植体周围的骨密度进行了术前、术后即刻和术后 3 个月的测量。结果:结果显示,术后 3 个月的二次稳定性(ISQ)(平均值±SD)为 76.20±5.43,与种植体植入后即刻的一次稳定性(ISQ)(平均值±SD)65.20±4.96 相比,二次稳定性(ISQ)在统计学上有显著提高(P <0.001)。术后即刻和术后三个月的骨密度与术前相比均有明显增加(分别为 p <0.001 和 p =0.002)。结论:使用登沙车针进行骨质增生是一种有效的方法,可提高磨牙关节间隔膜即刻植入种植体的稳定性。
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引用次数: 0
INVESTIGATING THE EFFECTS OF GLUMA DESENSITIZING AGENT ON REDUCING POST-OPERATIVE SENSITIVITY FOLLOWING COMPOSITE RESTORATIONS 研究格鲁玛脱敏剂对降低复合树脂修复术后敏感性的影响
Pub Date : 2024-06-04 DOI: 10.21608/adjalexu.2024.263797.1467
Nessrin Magdy Abd- Elkader, Waleed Abd EL Meguid El Mahy, Rania Reda Afifi
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引用次数: 0
EVALUATION OF ATRAUMATIC AXIAL TOOTH EXTRACTION USING BENEX SYSTEM IN IMMEDIATE IMPLANT IN MAXILLARY ANTERIOR TEETH. (PROSPECTIVE CLINICAL TRIAL) 在上颌前牙即刻种植体中使用 benex 系统进行无创轴向拔牙的评估(前瞻性临床试验)。
Pub Date : 2024-06-04 DOI: 10.21608/adjalexu.2024.272613.1477
G. I. Mabrouk, M. Fahmy, Adham Alashwah, Yehia Elmahallawy
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引用次数: 0
EFFECT OF ASPARTAME ON ALBINO RATS’ PAROTID SALIVARY GLANDS (LIGHT MICROSCOPIC STUDY) 阿斯巴甜对白化大鼠腮腺唾液腺的影响(光学显微镜研究)
Pub Date : 2024-06-04 DOI: 10.21608/adjalexu.2024.246695.1437
H. E. Elfarnwany, Salwa Abdelsamad Younis, S. El-Darier, A. S. Eissa
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引用次数: 0
EVALUATION OF BONE AUGMENTATION USING AUTOLOGOUS TOOTH SHELL IN THE ESTHETIC ZONE OF NARROW MAXILLA (A CLINICAL STUDY) 使用自体牙壳在上颌骨狭窄的美容区进行骨增量的评估(一项临床研究)
Pub Date : 2024-06-04 DOI: 10.21608/adjalexu.2024.240808.1424
Salma Ahmed fouad Elshenawy, Samraa A. Elsheikh, Marwa G. Noureldin
INTRODUCTION: Following extraction of tooth, the alveolar bone is resorbed in different directions with variant measurements. The decrease in alveolar bone width is higher in amount than alveolar bone height resorption, and is most significant buccally. The autologous tooth shell (ATS) had been of great interest in dental research as for it's low cost and less aggressiveness than Autogenous bone (AB), also it showed similar composition to bone tissue. Furthermore, ATS proved to have osteogenic and osteoconductive characteristics as AB. MATERIALS AND METHODS: A prospective clinical trial was carried on 12 patients of both sexes between the ages of 20-45 years. Patients who were radiologically diagnosed with narrow maxillary ridge in the anterior and/or premolar area. Tooth shells were used to augment the narrow ridge, by fixing them buccally with osteosynthesis screws. Cerabone® bone granules and a resorbable collagen membrane were used. Measurement of horizontal ridge width (HRW) was done both preoperatively (HRW1) and 4 months postoperatively (HRW2) using CBCT. Participant patients were fully informed of the clinical trial and had to sign a written informed consent. RESULTS: The age of the selected sample size varied from 20 to 45 years old, with a mean of 42.08±2.19 , and there were three men and nine females. 10 cases underwent uneventful recovery showing no signs of infection while 2 cases showed dehiscence. ATS persisted and united to the narrow ridge four months after surgery. ATS was utilized in the augmentation of the narrow ridge, from a narrow ridge width HRW1 of mean value 4.46±0.51 mm to the final HRW2 of mean value 6.85±0.63mm after 4 months of surgery. The average horizontal ridge width gain HRWG was 2.40±0.41 mm. Cancellous bone density of augmented maxillary ridge showed minimal or no significant change 4 months post operatively. CONCLUSION: This study showed that autologous tooth shell improves esthetics and bone healing and bone thickness in the esthetic zone of maxilla. ATS is a potential replacement for traditional autologous bone grafts in the future.
引言:拔牙后,牙槽骨会从不同方向吸收,测量结果也不尽相同。牙槽骨宽度的减少量高于牙槽骨高度的吸收量,且颊侧最为显著。与自体骨(AB)相比,自体牙壳(ATS)成本低、侵蚀性小,而且其成分与骨组织相似,因此在牙科研究中备受关注。此外,事实证明 ATS 与 AB 骨一样具有成骨和骨诱导特性。材料与方法:对 12 名年龄在 20-45 岁之间的男女患者进行了前瞻性临床试验。患者经放射学诊断为前牙和/或前磨牙区上颌嵴狭窄。通过使用骨合成螺钉将牙壳固定在颊侧,以增大狭窄的牙脊。使用 Cerabone® 骨颗粒和可吸收胶原膜。术前(HRW1)和术后 4 个月(HRW2)使用 CBCT 测量水平脊宽(HRW)。参加临床试验的患者已被充分告知,并签署了书面知情同意书。结果:所选样本的年龄从 20 岁到 45 岁不等,平均年龄(42.08±2.19)岁,其中男性 3 例,女性 9 例。10 例患者恢复顺利,无感染迹象,2 例出现开裂。术后 4 个月,ATS 持续存在并与窄嵴结合。手术 4 个月后,ATS 被用于增加窄脊,从平均值为 4.46±0.51 mm 的窄脊宽度 HRW1 增加到最终平均值为 6.85±0.63 mm 的 HRW2。平均水平脊宽增量 HRWG 为 2.40±0.41 毫米。术后 4 个月,增量上颌嵴的松质骨密度变化极小或无明显变化。结论:这项研究表明,自体牙壳能改善上颌美学、骨愈合和美学区的骨厚度。自体牙壳有可能在未来取代传统的自体骨移植。
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引用次数: 0
APICAL MICROLEAKAGE OF ROOT END RESECTED TEETH AFTER ORTHOGRADE OBTURATION USING A BIOCERAMIC SEALER: AN IN VITRO BACTERIOLOGICAL STUDY 使用生物陶瓷封闭剂进行正交封固后根端切除牙齿的根尖微渗漏:体外细菌学研究
Pub Date : 2024-06-02 DOI: 10.21608/adjalexu.2024.266923.1475
M. M. Mansour, Sybel M. Moussa, Marwa A. Meheissen, Mahmoud Aboelseoud
BACKGROUND: E ndodontic surgery becomes a practical choice when non-surgical interventions are ineffective or are not expected to yield improved results. Limited access and technical challenges may prevent the implementation of controlled retrograde procedures in certain teeth . AIM OF THE STUDY: The objective was to compare bacterial microleakage of root end resected teeth after orthograde obturation using a single cone technique with a bioceramic sealer versus MTA retrofilling. MATERIALS AND METHODS: Thirty human extracted maxillary incisors were prepared and divided randomly into three groups. In group1, the canals were filled using the single cone technique with bioceramic sealer, followed by root resection 3 mm from the apex. Group 2 received standard retrograde ultrasonic preparation and retrograde obturation with mineral trioxide aggregate (MTA) and group 3 negative control. Subsequently, the roots were placed in a sterile experimental model and filled coronally with E. faecalis bacterial suspension for 30 days. Turbidity and the time taken for turbidity in the broth were analyzed to assess bacterial microleakage from the canal . RESULTS: The study revealed that there was no statistically significant difference in bacterial microleakage observed between the two test groups . CONCLUSION: Performing root end resection following a single cone technique obturation, along with a bioceramic sealer, may offer a favorable alternative approach when compared to the established gold standard MTA retrograde obturation.
背景:当非手术干预无效或预期不会产生更好的效果时,牙科手术就成了一种实用的选择。在某些情况下,有限的通道和技术上的挑战可能会阻碍可控逆行手术的实施。研究目的:目的是比较使用生物陶瓷封闭剂的单锥技术与 MTA 后填充法进行正交封固后根端切除牙齿的细菌微渗漏情况。材料和方法:制备 30 颗人类拔出的上颌切牙,并随机分为三组。第一组使用生物陶瓷封闭剂单锥技术充填牙槽骨,然后在距牙根顶 3 毫米处切除牙根。第 2 组接受标准的逆行超声波预备,并用三氧化物矿物质骨料(MTA)进行逆行封闭,第 3 组为阴性对照。随后,将牙根置于无菌实验模型中,用粪大肠杆菌细菌悬浮液填充牙根冠部,持续 30 天。分析肉汤的浑浊度和浑浊所需的时间,以评估细菌从牙管微渗漏的情况。结果:研究表明,两个试验组之间的细菌微渗漏没有明显的统计学差异。结论:与已确立的黄金标准 MTA 逆行封堵相比,在单锥技术封堵后进行根端切除,同时使用生物陶瓷封堵器,可能是一种有利的替代方法。
{"title":"APICAL MICROLEAKAGE OF ROOT END RESECTED TEETH AFTER ORTHOGRADE OBTURATION USING A BIOCERAMIC SEALER: AN IN VITRO BACTERIOLOGICAL STUDY","authors":"M. M. Mansour, Sybel M. Moussa, Marwa A. Meheissen, Mahmoud Aboelseoud","doi":"10.21608/adjalexu.2024.266923.1475","DOIUrl":"https://doi.org/10.21608/adjalexu.2024.266923.1475","url":null,"abstract":"BACKGROUND: E ndodontic surgery becomes a practical choice when non-surgical interventions are ineffective or are not expected to yield improved results. Limited access and technical challenges may prevent the implementation of controlled retrograde procedures in certain teeth . AIM OF THE STUDY: The objective was to compare bacterial microleakage of root end resected teeth after orthograde obturation using a single cone technique with a bioceramic sealer versus MTA retrofilling. MATERIALS AND METHODS: Thirty human extracted maxillary incisors were prepared and divided randomly into three groups. In group1, the canals were filled using the single cone technique with bioceramic sealer, followed by root resection 3 mm from the apex. Group 2 received standard retrograde ultrasonic preparation and retrograde obturation with mineral trioxide aggregate (MTA) and group 3 negative control. Subsequently, the roots were placed in a sterile experimental model and filled coronally with E. faecalis bacterial suspension for 30 days. Turbidity and the time taken for turbidity in the broth were analyzed to assess bacterial microleakage from the canal . RESULTS: The study revealed that there was no statistically significant difference in bacterial microleakage observed between the two test groups . CONCLUSION: Performing root end resection following a single cone technique obturation, along with a bioceramic sealer, may offer a favorable alternative approach when compared to the established gold standard MTA retrograde obturation.","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141273228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF IMMEDIATE LOADED IMPLANTS PLACED USING THE SOCKET SHIELD TECHNIQUE IN THE ESTHETIC ZONE (A RANDOMIZED CONTROLLED CLINICAL TRIAL) 评估在美容区使用牙槽屏蔽技术植入即刻加载的种植体(随机对照临床试验)
Pub Date : 2024-05-06 DOI: 10.21608/adjalexu.2023.192795.1351
Mohamed Shehata, Adham Alashwah, Rania Ahmed, Ahmed Ahmed
INTRODUCTION: Once teeth are extracted, the alveolar bone with the labial bone plate reduction occurs as a consequence of the absence of blood flow. The socket-shield technique )SST) was introduced to end these consequences. OBJECTIVES: Our goal was to compare between the conventional approach and the SST perspectives; clinical and radiographical. MATERIALS AND METHODS: 20 individuals were parted into 2 groups; the study group: The (SST) with immediate loading was applied 10 implants in the anterior maxilla. The control group: 10 implants were instantly placed using immediate implant placement (IIP) along with the immediate loading. For both groups, CBCT-scans were pre-operatively evaluated and 6 months period for evaluating the dimensional changes within the labial bone plates including both the vertical and horizontal bone loss (VBL, HBL), measuring of clinical attachment loss (CAL), the dental implant stability quotients (DISQs) and the pink esthetic scores (PES), RESULTS: The mean Dental Implant Stability (DISQ) was 77.92+2.44 and 75.14+2.34 in control and study groups respectively 6 months postoperatively, the average HBL bone level 6 months postoperative in Group 1 was 6.88+0.97mm, and in Group 2 was 6.74+0.93mm. While mean VBL level after 6 months of follow up in Groups 1 and 2 was 0.93+0.57mm, and 1.55+0.85mm respectively. The mean PES in Group 1 was 12.10+0.57 after 6 months, while in Group 2 was 7.80+1.14. The mean CAL 6 months Post-operatively in Group 1 and Group 2 was 0.90+0.57mm and 1.50+0.85mm respectively. There was high statistically significant difference between the study and control group. CONCLUSIONS: The technique of socket-shield was conserved the labial root part
简介:拔牙后,由于缺乏血流,牙槽骨和唇侧骨板会发生萎缩。为了消除这些后果,人们引入了窝沟封闭技术(SST)。目的:我们的目标是比较传统方法和 SST 的临床和影像学效果。材料和方法:20 名患者分成两组:研究组:研究组:在上颌骨前部植入 10 个种植体,采用即刻加载法(SST)。对照组对照组:使用即刻种植体植入法(IIP)和即刻加载法植入 10 个种植体。两组患者术前和术后 6 个月都要进行 CBCT 扫描,以评估唇侧骨板的尺寸变化,包括垂直和水平骨量损失(VBL、HBL)、临床附着力损失测量(CAL)、种植体稳定性商数(DISQ)和粉色美学评分(PES)。对照组和研究组术后 6 个月的平均 HBL 骨水平分别为 6.88+0.97mm 和 6.74+0.93mm。随访 6 个月后,第一组和第二组的平均 VBL 水平分别为 0.93+0.57 毫米和 1.55+0.85 毫米。第一组 6 个月后的平均 PES 为 12.10+0.57,第二组为 7.80+1.14。第一组和第二组术后 6 个月的平均 CAL 分别为 0.90+0.57mm 和 1.50+0.85mm。研究组与对照组在统计学上差异很大。结论:窝沟封闭技术保留了唇侧牙根部分
{"title":"EVALUATION OF IMMEDIATE LOADED IMPLANTS PLACED USING THE SOCKET SHIELD TECHNIQUE IN THE ESTHETIC ZONE (A RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"Mohamed Shehata, Adham Alashwah, Rania Ahmed, Ahmed Ahmed","doi":"10.21608/adjalexu.2023.192795.1351","DOIUrl":"https://doi.org/10.21608/adjalexu.2023.192795.1351","url":null,"abstract":"INTRODUCTION: Once teeth are extracted, the alveolar bone with the labial bone plate reduction occurs as a consequence of the absence of blood flow. The socket-shield technique )SST) was introduced to end these consequences. OBJECTIVES: Our goal was to compare between the conventional approach and the SST perspectives; clinical and radiographical. MATERIALS AND METHODS: 20 individuals were parted into 2 groups; the study group: The (SST) with immediate loading was applied 10 implants in the anterior maxilla. The control group: 10 implants were instantly placed using immediate implant placement (IIP) along with the immediate loading. For both groups, CBCT-scans were pre-operatively evaluated and 6 months period for evaluating the dimensional changes within the labial bone plates including both the vertical and horizontal bone loss (VBL, HBL), measuring of clinical attachment loss (CAL), the dental implant stability quotients (DISQs) and the pink esthetic scores (PES), RESULTS: The mean Dental Implant Stability (DISQ) was 77.92+2.44 and 75.14+2.34 in control and study groups respectively 6 months postoperatively, the average HBL bone level 6 months postoperative in Group 1 was 6.88+0.97mm, and in Group 2 was 6.74+0.93mm. While mean VBL level after 6 months of follow up in Groups 1 and 2 was 0.93+0.57mm, and 1.55+0.85mm respectively. The mean PES in Group 1 was 12.10+0.57 after 6 months, while in Group 2 was 7.80+1.14. The mean CAL 6 months Post-operatively in Group 1 and Group 2 was 0.90+0.57mm and 1.50+0.85mm respectively. There was high statistically significant difference between the study and control group. CONCLUSIONS: The technique of socket-shield was conserved the labial root part","PeriodicalId":7723,"journal":{"name":"Alexandria Dental Journal","volume":"31 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141007785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Autogenous Fresh Demineralized Dentin and Beta-Tricalcium Phosphate in Immediate Implant Placement of Mandibular Molars (Randomized Clinical Controlled Trial) 自体新鲜脱矿物质牙本质与β-磷酸三钙在下颌磨牙即刻种植中的比较(随机临床对照试验)
Pub Date : 2024-05-05 DOI: 10.21608/adjalexu.2023.216442.1389
Ahmed Abulhassan, Gaffar El Halawani, Ossama Sweedan
INTRODUCTION: Autogenous fresh demineralized dentin, a graft used in immediate implant placement, has proven successful. It shares a similar chemical composition to human bone, making it biocompatible and capable of promoting osteoinductive and osteoconductive properties. β-tricalcium phosphate (β-TCP) is a widely employed synthetic bone graft material for filling gaps during immediate implant placement, particularly in posterior molars. OBJECTIVES: To compare the clinical and radiographic effects of fresh demineralized dentin and β-tricalcium phosphate as graft materials on bone density, crestal bone loss, and implant stability used in alveolar bone regeneration for immediate implant placement in mandibular molars. MATERIALS AND METHODS: The study included sixteen patients with unrestorable mandibular molars recruited and randomly allocated into two equal groups. The study group received fresh Demineralized Dentin Grafting (DDG), while the control group received β-tricalcium phosphate. All patients were followed clinically and radiologically for six months to assess parameters such as implant stability, crestal bone loss, and bone density. RESULTS: Crestal bone loss was significantly higher in the β-tricalcium phosphate group compared wtih the DDG group. Implant stability was significantly higher in the DDG group compared with the β-tricalcium phosphate group; the percentage change of bone density was significantly higher in the DDG group compared with the β-Tri Calcium Phosphate group. CONCLUSION: Autogenous fresh demineralized dentin may be a more favorable graft material compared to β-tricalcium phosphate for alveolar bone regeneration in immediate implant placement of mandibular molars. Fresh demineralized dentin was associated with superior crestal
简介:自体新鲜脱矿牙本质是一种用于即刻种植的移植物,已被证明是成功的。它与人体骨骼的化学成分相似,具有生物相容性,能促进骨诱导和骨诱导特性。β-磷酸三钙(β-TCP)是一种广泛使用的合成骨移植材料,可用于即刻种植体植入过程中的间隙填充,尤其是后磨牙。目的比较新鲜去矿化牙本质和β-磷酸三钙作为移植材料在下颌磨牙牙槽骨再生即刻种植体植入过程中对骨密度、骨嵴损失和种植体稳定性的临床和放射学影响。材料与方法:研究对象包括 16 名无法拔除的下颌磨牙患者,他们被随机分配到两个相同的小组。研究组接受新鲜脱矿质牙本质移植(DDG),对照组接受β-磷酸三钙。对所有患者进行为期 6 个月的临床和放射学随访,以评估植入物的稳定性、嵴骨损失和骨密度等参数。结果:与 DDG 组相比,β-磷酸三钙组的基底骨质流失明显较高。与β-磷酸三钙组相比,DDG组的种植体稳定性明显更高;与β-磷酸三钙组相比,DDG组的骨密度变化百分比明显更高。结论:在下颌磨牙即刻种植中,自体新鲜脱矿牙本质可能是比β-磷酸三钙更有利的牙槽骨再生移植材料。新鲜的去矿物质牙本质与优越的牙槽骨嵴相关。
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引用次数: 0
EVALUATION OF COMPUTER ASSISTED DESIGN COMPUTER ASSISTED MANUFACTUREING (CAD/CAM) OSTEOTOMY GUIDE IN BILATERAL MANDIBULAR SAGITTAL SPLIT OSTEOTOMY (A RANDOMIZED CONTROLLED CLINICAL TRIAL) 计算机辅助设计计算机辅助制造(CAD/CAM)截骨导板在双侧下颌骨矢状劈开截骨术中的应用评估(随机对照临床试验)
Pub Date : 2024-05-05 DOI: 10.21608/adjalexu.2023.222909.1398
Ahmed Shararah, A. Sharara, Samraa A. Elsheikh, Adham Alashwah, Marwa G. Noureldin
INTRODUCTION: The introduction of CAD/CAM technology in orthognathic surgery planning has facilitated the procedure and enabled more predictable results. This study was designed to introduce and evaluate the clinical use of a CAD/CAM surgical guide for bilateral sagittal split osteotomy (BSSO) in the correction of dentofacial deformity cases with skeletal class 2 or 3. AIM OF THE STUDY: To evaluate the efficiency of guided osteotomy in orthognathic surgery. Materials and Methods: This study was conducted on 20 patients who underwent bilateral sagittal osteotomy (BSO) procedures. Ten patients (the control group) were treated with the conventional method, without an osteotomy guide. The other 10 patients (the study group) were treated with a CAD/CAM bone-borne guide. Postoperative patient evaluation was performed clinically by comparing the operation time post operative pain and sensory nerve involvement at 1 week, 2 weeks, and 3 months. Radiographic evaluation was performed by computed tomography (CT) at 1 month postoperatively. RESULTS: The surgical outcome revealed the satisfactory correction of their skeletal deformity. The study group showed significantly better results than control group concerning operation time, Visual Analogue Scale, and sensory nerve involvement (p ≤ 0.05.) CONCLUSION: Within the limitations of this study, it can be considered that CAD /CAM osteotomy guide for BSSO is superior to non-guided BSSO regarding the operation time and sensory nerve involvement.
引言:在正颌外科手术规划中引入 CAD/CAM 技术,促进了手术的顺利进行,并使手术效果更具可预测性。本研究旨在介绍和评估双侧矢状劈开截骨术(BSSO)的 CAD/CAM 手术导板在骨骼等级为 2 级或 3 级的颌面畸形矫治病例中的临床应用。研究目的:评估正颌外科手术中引导截骨术的效率。材料与方法:研究对象为接受双侧矢状截骨术(BSO)的 20 名患者。10名患者(对照组)采用传统方法治疗,不使用截骨引导器。另外 10 名患者(研究组)使用 CAD/CAM 骨导板进行治疗。术后患者的临床评估是通过比较术后 1 周、2 周和 3 个月的疼痛和感觉神经受累情况来进行的。术后 1 个月通过计算机断层扫描(CT)进行放射学评估。结果:手术结果显示,患者的骨骼畸形矫正效果令人满意。研究组在手术时间、视觉模拟量表和感觉神经受累方面的结果明显优于对照组(P≤0.05)。 结论:在本研究的局限性内,可以认为在手术时间和感觉神经受累方面,CAD /CAM 截骨引导 BSSO 优于非引导 BSSO。
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引用次数: 0
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Alexandria Dental Journal
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