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A model for quality assessment in cervical cytology used as a screening test. 宫颈细胞学质量评估模型,用于筛查试验。
C Quantin, L Dusserre, A M Montaud, C Mottot, J P Feldman

Although many reliability studies on cervical cytology have been carried out, measurements of sensitivity and specificity have rarely been made since biopsies are not often performed on patients with a negative smear result. This screening assessment was performed over 3 years, using a database of 230,167 smears from 177,051 women. It would seem that cervical cytology has a high specificity (over 99%) but a relatively low sensitivity (61%). Values for sensitivity (exceeding 95%) and specificity (exceeding 99%) for invasive carcinoma should be regarded as reasonably accurate as all incident cases of symptomatic cervical carcinoma are recorded in the Burgundy register. The sensitivity (57%) for pre-invasive lesions is underestimated while their prevalence is overestimated: the lack of organized screening leads to the loss of prevalent cases. The predictive value of a positive smear is 76% for moderate-severe dysplasia, 85% for in situ carcinoma and over 95% for invasive carcinoma.

虽然对宫颈细胞学进行了许多可靠性研究,但很少对敏感性和特异性进行测量,因为对涂片结果阴性的患者通常不进行活组织检查。这项筛查评估在3年内进行,使用了来自177051名妇女的230167份涂片的数据库。宫颈细胞学似乎具有高特异性(99%以上),但相对较低的敏感性(61%)。浸润性癌的敏感性(超过95%)和特异性(超过99%)的值应被认为是合理准确的,因为所有有症状的宫颈癌病例都记录在勃艮第登记册中。侵袭前病变的敏感性(57%)被低估,而其患病率被高估:缺乏有组织的筛查导致流行病例的损失。涂片阳性对中重度非典型增生的预测价值为76%,对原位癌的预测价值为85%,对浸润性癌的预测价值超过95%。
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引用次数: 0
Reactions of doctors to various forms of feedback designed to improve the sampling quality of cervical smears. 医生对旨在改善子宫颈细胞检验抽样质量的各种反馈意见的反应。
F Buntinx, J A Knottnerus, H F Crebolder, G G Essed

Three different forms of feedback designed to improve the sampling quality of cervical smears were tested in a randomized controlled trial among 179 physicians. The reactions of the doctors to the various interventions are reported as they appeared from their answers in a questionnaire. The influence of the interventions on the employed sampling technique is described on the basis of their answers to a telephone inquiry. The inclusion in laboratory protocols of an evaluation of the sampling quality of the submitted smears was largely appreciated, as was specific advice offered on indication. Monthly overviews comparing the performance of the individual doctor to that of his peers were esteemed by three out of four. Further information, help or training was requested more frequently than average by physicians obtaining inadequately sampled smears relatively often. The number of doctors using the combined spatula and Cytobrush method as sampling technique doubled during the study period.

在179名医生的随机对照试验中,测试了三种不同形式的反馈,旨在提高宫颈涂片的抽样质量。医生对各种干预措施的反应是根据他们在问卷中的回答来报告的。干预措施对所采用的抽样技术的影响是根据他们对电话询问的回答来描述的。在实验室规程中列入了对所提交的涂片取样质量的评价,并就指征问题提出了具体建议,这在很大程度上受到赞赏。每月将医生个人的表现与同行的表现进行比较的综述得到了四分之三的人的认可。进一步的信息,帮助或培训的要求比平均频率更高的医生获得不充分的抽样涂片相对频繁。在研究期间,使用混合刮刀和细胞刷法作为采样技术的医生数量增加了一倍。
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引用次数: 0
The Flemish Centre for the Study of Perinatal Epidemiology and its registry. 佛兰德围产期流行病学研究中心及其登记处。
A Vleugels, A Bekaert

The Flemish Centre for the Study of Perinatal Epidemiology was formally established in 1986. Its objectives are the promotion of perinatal epidemiology and the study of maternal and perinatal mortality and morbidity. One of the means to accomplish these objectives was the creation of a databank of perinatal medicine. The registry at present covers almost 80% of all deliveries in Flanders. The registry indicates a maternal death rate of 5.8/100,000 living births whereas the Belgian official national statistics indicate a maternal death rate of 2.8/100,000. This means that either the matter is under reported at the national level or there is a real problem in the Flemish part of the country. The perinatal death rate varies among the participating services form 3.9 to 22.4%.

佛兰德围产期流行病学研究中心于1986年正式成立。其目标是促进围产期流行病学和研究产妇和围产期死亡率和发病率。实现这些目标的手段之一是建立围产期医学数据库。该登记目前覆盖了法兰德斯所有分娩的近80%。登记显示,产妇死亡率为每10万活产5.8例,而比利时官方国家统计数据显示,产妇死亡率为每10万活产2.8例。这意味着,要么这个问题在国家一级没有得到充分报道,要么这个国家的佛兰芒地区确实存在问题。参与服务机构的围产期死亡率从3.9%到22.4%不等。
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引用次数: 0
Medical audit and quality of care--a new English initiative. 医疗审计和护理质量——一项新的英国倡议。
D Macpherson, T Mann

In 1989 the Government in the UK announced a fundamental review of the financing of the National Health Service (NHS). Before the review, health authorities were responsible for both establishing need and providing services. Health Authorities are now allocated resources with which they commission services from managerially independent provider units. In the discussion that preceded the review concern was expressed about standards of clinical care given by doctors. It was recognised that these were professional issues which could not be directly addressed through the commissioning process, therefore within its NHS review proposals, the Government made clear its expectation that all doctors working in the NHS should participate in medical audit. This was defined as a systematic peer review of their work, including procedures used for diagnosis and treatment, the use of resources and the resulting outcome for patients. Managers should be provided with regular general reports of audit activity. These proposals for medical audit have been well received by the medical profession, who are now working closely with the Government to put them into practice.

1989年,联合王国政府宣布对国民保健服务(国民保健服务)的资金筹措进行根本审查。在审查之前,卫生当局负责确定需求并提供服务。卫生当局现在获得资源,委托管理上独立的提供单位提供服务。在审查之前的讨论中,对医生提供的临床护理标准表示了关注。人们认识到,这些都是专业问题,无法通过委托程序直接解决,因此,政府在其国民保健制度审查建议中明确表示,它期望在国民保健制度工作的所有医生都应参与医疗审计。这被定义为对他们的工作进行系统的同行评审,包括用于诊断和治疗的程序,资源的使用以及对患者的结果。应定期向管理人员提供审计活动的总报告。这些医疗审计建议得到了医学界的好评,他们目前正与政府密切合作,将这些建议付诸实施。
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引用次数: 0
Inappropriate emergency test ordering in a general hospital: preliminary reports. 综合医院急诊检测命令不当:初步报告。
F Perraro, P Rossi, C Liva, A Bulfoni, G Ganzini, A Giustinelli, E Tonutti, P G Sala, P Santini

An assessment was made on emergency laboratory test ordering at Udine General Hospital (Italy) to investigate the reasons for the excessive number of requested tests. All the orders for emergency laboratory tests during one week in June 1990 were studied. For each test the time of the order was recorded for every day of the week. The most important aspect of our investigation is the distribution of the orders during the day: in fact, test orders reached two peaks, the upper between 7 and 11 a.m., and the lower between 3 and 6 p.m. The analysis of the record cards showed that 42% of the orders were inappropriate. These preliminary findings were very useful in making the consensus on a Quality Assurance program easier, to improve the use of the Emergency Laboratory by doctors and nurses. Some preliminary results in the Emergency Medicine Department confirmed the validity of this program.

对乌迪内总医院(意大利)的紧急化验室检查订单进行了评估,以调查要求检查次数过多的原因。研究了1990年6月一周内所有紧急化验室检查的命令。对于每个测试,订单的时间记录为一周中的每一天。我们调查的最重要的方面是订单在白天的分布:事实上,测试订单有两个高峰,高峰在上午7点到11点之间,最低点在下午3点到6点之间。对记录卡的分析显示,42%的订单是不合适的。这些初步的发现对于使质量保证方案更容易达成共识,提高医生和护士对急诊实验室的使用非常有用。急诊医学部的一些初步结果证实了该方案的有效性。
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引用次数: 0
How to induce physicians to engage in quality assurance activities in a university hospital: a policy. 大学医院如何引导医生参与质量保证活动:一项政策。
A Giraud, D Jolly

This article reports on a 3-year quality assurance (QA) support activity in the Assistance Publique-Hôpitaux de Paris, a large university hospital system covering the Greater Paris area. This activity stressed the interprofessional and voluntary character of QA. As well as showing the traditional reservations that usually prevent physicians from embracing QA. French physicians have specific problems with the word "evaluation" that has for them greater monetary than scientific connotations. In addition, the above-mentioned reservations are aggravated by the background culture and career structure of university physicians in France. In spite of these initial difficulties the support programme succeeded in getting QA off the ground in 60 departments in 25 hospitals. The need for a well developed medical information system as an incentive for QA activities in AP is discussed.

本文报道了巴黎援助Publique-Hôpitaux(一个覆盖大巴黎地区的大型大学医院系统)为期3年的质量保证(QA)支持活动。这个活动强调了QA的跨专业和自愿性。同时也显示了传统的保留意见,这通常会阻止医生接受QA。法国医生对“评估”这个词有特殊的问题,因为这个词对他们来说有更多的金钱含义而不是科学含义。此外,法国大学医生的背景文化和职业结构加剧了上述保留。尽管最初存在这些困难,支助方案还是成功地在25家医院的60个科室开展了质量保证。讨论了建立完善的医疗信息系统以激励AP的QA活动的必要性。
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引用次数: 0
Quality control of laboratory results in real time. 实验室结果的实时质量控制。
W Picco, L Pinna Pintor, G Baruzzo, O Pistono, F Triumbari, P Pinna Pintor

An integrated informatic system may have an important role in identifying and reducing those errors which affect the reliability of laboratory results. The present work reports on the development of a system that, by means of a computer connected with laboratory instrumentation, allows monitoring of global error (bias, random, gross) using classical statistical quality control systems, integrated by auxiliary methods built on a database stored in the computer. These methods succeeded in greatly reducing bias and random error in the most frequent laboratory tests. Further methods to find, quantify, and reduce the gross and extra-analytical errors are under development.

综合信息系统可能在识别和减少影响实验室结果可靠性的错误方面发挥重要作用。本工作报告是关于开发一种系统的情况,该系统通过与实验室仪器相连的计算机,可以使用经典的统计质量控制系统监测全局误差(偏差、随机、总误差),并通过计算机中存储的数据库所建立的辅助方法加以综合。这些方法成功地大大减少了最常见的实验室测试中的偏差和随机误差。进一步的方法来发现、量化和减少总的和分析外的错误正在开发中。
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引用次数: 0
Variability among geriatricians in the evaluation of functional disabilities and rehabilitation needs of the elderly. 老年人功能障碍和康复需求评估中老年医生的差异。
I Aramini, P Morosini, E Ricci, S Ratto, M Petrini, A Banchero

A formal variability study has been carried out in a geriatric hospital in Genoa, Italy, in order to estimate the degree of agreement between geriatricians in disability and functional assessment, recommendation for rehabilitation treatments, need for mobility and daily activities aids, and decisions about optimal place of treatment (own home, sheltered housing, old peoples' home, nursing home). Sixteen long-stay geriatric patients, average age 83 years, were visited by eight geriatricians, a patient receiving from two to five visits. The participating physicians could visit the patients at their leisure, had access to clinical records and could interview a nurse well acquainted with the patient. A marked variability was observed for most items, e.g. the agreement concerning the recommendation for individual physiotherapy was only 52%. The results of this study may not be generalized to other situations and to actual practice; however, variability studies of this kind, that assess diagnosis habits, treatment and managerial decisions at the same time, may be useful to pinpoint the most important problems and to stimulate professionals' participation in proper Quality Assurance projects.

在意大利热那亚的一家老年医院进行了一项正式的变异性研究,以估计老年医生在残疾和功能评估、康复治疗建议、行动能力和日常活动辅助设备需求以及最佳治疗地点(自己的家、庇护住房、老年人之家、养老院)的决定方面的一致程度。16名长期住院的老年患者,平均年龄83岁,由8名老年医生访问,患者接受2至5次访问。参与的医生可以在闲暇时间访问患者,获得临床记录,并可以采访熟悉患者的护士。在大多数项目中观察到明显的差异,例如,关于个人物理治疗建议的一致性仅为52%。本研究的结果可能不能推广到其他情况和实际操作中;然而,这种同时评估诊断习惯、治疗和管理决策的变异性研究可能有助于查明最重要的问题,并刺激专业人员参与适当的质量保证项目。
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引用次数: 0
Quality assurance in radiotherapy: physical and technical aspects. 放射治疗的质量保证:物理和技术方面。
B J Mijnheer

Since a radiotherapy department is a clinical and technical entity, quality assurance (QA) is a team effort. This is necessary for the treatment of a patients with the required high degree of accuracy and precision. The physical and technical aspects of QA programmes performed in radiotherapy institutions have been reviewed in this paper. Firstly, the accuracy required in radiotherapy has been discussed. An increasing amount of clinical evidence indicates that an accuracy of 3.5% in the dose value at the specification points and an accuracy of less than 5 mm in the position of the field with respect to the target volume in the patient is required. Secondly, various aspects of QA programmes related to beam characteristics of treatment machines, treatment planning and treatment verification have been elucidated. It is recommended that international organizations formulate minimum and ideal QA programmes for this purpose. Finally, some recent developments in the field of treatment verification concerning portal imaging and in vivo dosimetry, partly sponsored by the CEC/AIM programme, have been illustrated in more detail. The latter project concerns the further development of an on-line electronic portal imaging device for checking the correct position of the target volume with respect to the radiation beam.

由于放射治疗科是一个临床和技术实体,质量保证(QA)是一个团队的努力。这对于治疗患者所需要的高度准确性和精密度是必要的。本文回顾了放射治疗机构进行的质量保证项目的物理和技术方面。首先,讨论了放射治疗所需的精度。越来越多的临床证据表明,在指定点的剂量值的准确性为3.5%,并且相对于患者的靶体积,在场的位置的准确性小于5mm。其次,阐述了与治疗机光束特性、治疗计划和治疗验证相关的QA程序的各个方面。建议国际组织为此目的制订最低限度和理想的质量保证方案。最后,由CEC/AIM项目部分赞助的关于门静脉成像和体内剂量学的治疗验证领域的一些最新进展已被更详细地说明。后一个项目涉及进一步发展一种联机电子门户成像装置,用于检查目标体相对于辐射束的正确位置。
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引用次数: 0
Accessibility to primary health care centers: experience and evaluation of an appointment system program. 初级卫生保健中心的可及性:预约系统项目的经验和评估。
M A Gogorcena, M Castillo, J Casajuana, F A Jové

Appropriate access to health care is one of the components of Primary Health Care (PHC) and it can be a good quality indicator. We present in this paper the results of 1 year of follow-up of an appointment system applied in 29 PHC centers in the Balearic Islands, Spain; the program was set up by the National Institute of Health. Telephonic appointment proportion increased from the first weeks, stabilizing at about 70%. The number of calls that it is necessary to make in order to get an appointment at peak time is now 1.5 and only 1 throughout the rest of the day. To determine changes in the waiting time and visit time, and the user opinion of the system, an enquiry was made to a sample of patients 1 month before, and 1 month, 6 months and 1 year after the program started. The waiting time is now less than 15 min for most of the people interviewed, in contrast with the previous situation when the waiting time was more than 30 min. The visit time is longer now and more than two thirds of the people think that care is better or much better than prior to the start of the program. These results have been verified in the waiting room (11.2 min mean waiting time and 7.2 min mean visit time). We conclude that we have achieved the goals of the appointment system program in all the centers covered by our department.

适当获得卫生保健是初级卫生保健的组成部分之一,它可以是一个良好的质量指标。我们在本文中介绍了在西班牙巴利阿里群岛29个初级保健中心应用的预约系统1年随访的结果;这个项目是由国家卫生研究院设立的。电话预约比例从第一周开始上升,稳定在70%左右。为了在高峰时间预约,现在需要拨打的电话数量是1.5次,而在一天的其他时间只有1次。为了确定等待时间和就诊时间的变化,以及用户对系统的意见,我们在项目开始前1个月、1个月、6个月和1年后对患者样本进行了调查。大多数受访者的等待时间现在不到15分钟,而之前的情况是等待时间超过30分钟。现在的就诊时间更长了,超过三分之二的人认为护理比计划开始前好或好得多。这些结果在候诊室得到了验证(平均等待时间11.2分钟,平均就诊时间7.2分钟)。我们的结论是,我们已经在我们部门覆盖的所有中心实现了预约制度计划的目标。
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引用次数: 0
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Quality assurance in health care : the official journal of the International Society for Quality Assurance in Health Care
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