Pub Date : 2025-02-01DOI: 10.1016/j.amjsurg.2024.115989
Tega Ebeye , Chantal R. Valiquette , Natalia Ziolkowski
{"title":"Exploring consent for animal-derived products in surgery","authors":"Tega Ebeye , Chantal R. Valiquette , Natalia Ziolkowski","doi":"10.1016/j.amjsurg.2024.115989","DOIUrl":"10.1016/j.amjsurg.2024.115989","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 115989"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.amjsurg.2024.116124
Anna Mary Jose, Aryan Rafieezadeh, Jordan Kirsch, Mikaiel Ebanks, Ilya Shnaydman, Gabriel Froula, Kartik Prabhakaran, Bardiya Zangbar
Background
Pregnant trauma patients present unique challenges in terms of assessment and management. This study assesses the impact of traumatic injuries on pregnant patients using a national trauma database.
Methods
ACS-TQIP (2020–2021) identified traumatically injured females aged ≥15 and ≤ 55. Propensity score matching compared pregnant and not-pregnant patients. Primary outcome was mortality, with secondary outcomes including length of stay (LOS), emergency department and discharge disposition, interventions, and complications.
Results
Of 947,000 traumatically injured females, 8421 (0.9 %) were pregnant. Pregnant patients (6.0 %) sustained firearm injuries more than not-pregnant patients (5.4 %) (p = 0.02). Pregnant patients had more severe thoracic (47.2%vs.9.4 %) and abdominal injuries (7.1%vs.4.8 %) compared to not-pregnant patients (p < 0.001). Among pregnant patients, 5.6 % had preterm labor, 2.6 % had cesarean sections, and 1.9 % had abortions. After matching, there was no significant difference in mortality between both groups (p = 0.40). Pregnant patients had longer ICU LOS (p < 0.05) and higher rates of unplanned return to ICU (p < 0.05).
Conclusions
Pregnant patients are more often victims of firearm violence, sustaining critical thoracic and abdominal injuries. These injuries demand increased interventions, introduce complications, and can be fatal.
{"title":"Unveiling the impact of trauma during pregnancy","authors":"Anna Mary Jose, Aryan Rafieezadeh, Jordan Kirsch, Mikaiel Ebanks, Ilya Shnaydman, Gabriel Froula, Kartik Prabhakaran, Bardiya Zangbar","doi":"10.1016/j.amjsurg.2024.116124","DOIUrl":"10.1016/j.amjsurg.2024.116124","url":null,"abstract":"<div><h3>Background</h3><div>Pregnant trauma patients present unique challenges in terms of assessment and management. This study assesses the impact of traumatic injuries on pregnant patients using a national trauma database.</div></div><div><h3>Methods</h3><div>ACS-TQIP (2020–2021) identified traumatically injured females aged ≥15 and ≤ 55. Propensity score matching compared pregnant and not-pregnant patients. Primary outcome was mortality, with secondary outcomes including length of stay (LOS), emergency department and discharge disposition, interventions, and complications.</div></div><div><h3>Results</h3><div>Of 947,000 traumatically injured females, 8421 (0.9 %) were pregnant. Pregnant patients (6.0 %) sustained firearm injuries more than not-pregnant patients (5.4 %) (p = 0.02). Pregnant patients had more severe thoracic (47.2%vs.9.4 %) and abdominal injuries (7.1%vs.4.8 %) compared to not-pregnant patients (p < 0.001). Among pregnant patients, 5.6 % had preterm labor, 2.6 % had cesarean sections, and 1.9 % had abortions. After matching, there was no significant difference in mortality between both groups (p = 0.40). Pregnant patients had longer ICU LOS (p < 0.05) and higher rates of unplanned return to ICU (p < 0.05).</div></div><div><h3>Conclusions</h3><div>Pregnant patients are more often victims of firearm violence, sustaining critical thoracic and abdominal injuries. These injuries demand increased interventions, introduce complications, and can be fatal.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 116124"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-31DOI: 10.1016/j.amjsurg.2025.116232
Jihun Cha, Thomas W Clements, Chad G Ball, Andrew W Kirkpatrick, Timothy Bax, John Mayberry
Damage control (DC) packing is used selectively in patients in shock with extensive abdominal, thoracic, perineal/genital/perirectal, neck/axillae/groin (junctional), and extremity injury to stop bleeding. In multiple casualty scenarios, DC packing may be used to facilitate an abbreviated surgery and thus "buy time". The packing is by guideline or military doctrine removed or exchanged 1-3 days later in a planned reoperation. In remote environments, however, where timely evacuation cannot occur and resources are limited, it may be necessary for packing to be left in place longer than 3 days. Also, in Large Scale Combat Operations, Multi-Domain Operations, and Distributed Maritime Operations, evacuation will be accomplished by nonsurgeons and may last several days. Prolonged retention of packing is associated with complications, but significant rebleeding may occur upon removal. This article reviews the benefits and hazards of DC packing removal to inform decision making by both surgeons and nonsurgeons. We conclude that except for Dismounted Complex Blast Injury most DC gauze packing does not mandatorily need to be removed or exchanged within a three-day window.
{"title":"Damage control packing: How long can it stay?","authors":"Jihun Cha, Thomas W Clements, Chad G Ball, Andrew W Kirkpatrick, Timothy Bax, John Mayberry","doi":"10.1016/j.amjsurg.2025.116232","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116232","url":null,"abstract":"<p><p>Damage control (DC) packing is used selectively in patients in shock with extensive abdominal, thoracic, perineal/genital/perirectal, neck/axillae/groin (junctional), and extremity injury to stop bleeding. In multiple casualty scenarios, DC packing may be used to facilitate an abbreviated surgery and thus \"buy time\". The packing is by guideline or military doctrine removed or exchanged 1-3 days later in a planned reoperation. In remote environments, however, where timely evacuation cannot occur and resources are limited, it may be necessary for packing to be left in place longer than 3 days. Also, in Large Scale Combat Operations, Multi-Domain Operations, and Distributed Maritime Operations, evacuation will be accomplished by nonsurgeons and may last several days. Prolonged retention of packing is associated with complications, but significant rebleeding may occur upon removal. This article reviews the benefits and hazards of DC packing removal to inform decision making by both surgeons and nonsurgeons. We conclude that except for Dismounted Complex Blast Injury most DC gauze packing does not mandatorily need to be removed or exchanged within a three-day window.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116232"},"PeriodicalIF":2.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-30DOI: 10.1016/j.amjsurg.2025.116228
Erin Kim , Alexis G. Antunez , Devak Nanua , Valerie Gavrila , Anthony Cuttitta , Lesly A. Dossett
Background
Routine preoperative testing for low-risk surgeries is often unnecessary and may result in preventable harm. While de-implementation strategies have reduced the frequency and proportion of unnecessary preoperative tests, the reach of the strategies and the provider-level adoption remain unclear. Understanding stakeholders’ perspective on these strategies is essential for widespread de-implementation.
Methods
Interviews were conducted with 18 anesthesiologists, surgeons, and physician assistants at a single academic institution. Thematic analysis was guided by the RE-AIM framework, and persistent barriers were assessed using the Consolidated Framework for Implementation Research.
Results
De-implementation strategies achieved high reach, with educational meetings emerging as the most effective strategy. Workflow variations significantly influenced adoption and implementation, with regular meetings and data sharing identified as facilitators for maintenance. Barriers were identified in the individual characteristics, inner setting, and outer setting levels.
Conclusions
Tailored de-implementation strategies are essential to overcoming provider- and institution-level barriers and to sustain guideline-concordant care.
{"title":"Overcoming inertia: Provider perspectives on de-implementation strategies in preoperative testing","authors":"Erin Kim , Alexis G. Antunez , Devak Nanua , Valerie Gavrila , Anthony Cuttitta , Lesly A. Dossett","doi":"10.1016/j.amjsurg.2025.116228","DOIUrl":"10.1016/j.amjsurg.2025.116228","url":null,"abstract":"<div><h3>Background</h3><div>Routine preoperative testing for low-risk surgeries is often unnecessary and may result in preventable harm. While de-implementation strategies have reduced the frequency and proportion of unnecessary preoperative tests, the reach of the strategies and the provider-level adoption remain unclear. Understanding stakeholders’ perspective on these strategies is essential for widespread de-implementation.</div></div><div><h3>Methods</h3><div>Interviews were conducted with 18 anesthesiologists, surgeons, and physician assistants at a single academic institution. Thematic analysis was guided by the RE-AIM framework, and persistent barriers were assessed using the Consolidated Framework for Implementation Research.</div></div><div><h3>Results</h3><div>De-implementation strategies achieved high reach, with educational meetings emerging as the most effective strategy. Workflow variations significantly influenced adoption and implementation, with regular meetings and data sharing identified as facilitators for maintenance. Barriers were identified in the individual characteristics, inner setting, and outer setting levels.</div></div><div><h3>Conclusions</h3><div>Tailored de-implementation strategies are essential to overcoming provider- and institution-level barriers and to sustain guideline-concordant care.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"242 ","pages":"Article 116228"},"PeriodicalIF":2.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143147488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Complete spinal cord injury (SCI) is associated with severe colon dysmotility and therefore may be associated with higher risk of leak following primary repair or anastomosis for concomitant colon injury.
Methods
TQIP database study, patients with complete SCI and associated colon injuries who underwent primary repair (PR) or resection with primary anastomosis (RPA) were compared to those who underwent ostomy alone using propensity score matching.
Results
Ninety-nine patients treated with a colostomy were matched with 215 treated with PR or RPA. Patients treated with colostomy were more likely to develop severe sepsis post-operatively (13.1 % vs 4.2 %, p = 0.004). Subgroup analysis, comparing colostomy versus PR or colostomy versus RPA, showed again a higher incidence of postoperative severe sepsis in the colostomy group.
Conclusions
Primary repair and/or RPA are associated with a lower incidence of postoperative severe sepsis than colostomy and should be considered in patients with combined SCI and colon injury.
{"title":"Colon injuries in the presence of complete spinal cord injury: Primary repair or colostomy?","authors":"Wei Huang , Caitlyn Braschi , Natalie Hodges , Yu Cheng Chiu , Demetrios Demetriades","doi":"10.1016/j.amjsurg.2025.116225","DOIUrl":"10.1016/j.amjsurg.2025.116225","url":null,"abstract":"<div><h3>Background</h3><div>Complete spinal cord injury (SCI) is associated with severe colon dysmotility and therefore may be associated with higher risk of leak following primary repair or anastomosis for concomitant colon injury.</div></div><div><h3>Methods</h3><div>TQIP database study, patients with complete SCI and associated colon injuries who underwent primary repair (PR) or resection with primary anastomosis (RPA) were compared to those who underwent ostomy alone using propensity score matching.</div></div><div><h3>Results</h3><div>Ninety-nine patients treated with a colostomy were matched with 215 treated with PR or RPA. Patients treated with colostomy were more likely to develop severe sepsis post-operatively (13.1 % vs 4.2 %, p = 0.004). Subgroup analysis, comparing colostomy versus PR or colostomy versus RPA, showed again a higher incidence of postoperative severe sepsis in the colostomy group.</div></div><div><h3>Conclusions</h3><div>Primary repair and/or RPA are associated with a lower incidence of postoperative severe sepsis than colostomy and should be considered in patients with combined SCI and colon injury.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"242 ","pages":"Article 116225"},"PeriodicalIF":2.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143147329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-30DOI: 10.1016/j.amjsurg.2025.116226
Elham Navab , Nicholas Legacy , Kristen R. Haase , Laura Freeman , Ainslee Smith , Amir Hossein Goudarzian , Ana Patricia Ayala , Valentina Donison , Ailsa Sirois , Farshad Sharifi , Tyler R. Chesney , Camilla Wong , Joanne Callow , Dominque Boswell , Shabbir Alibhai , Martine Puts
Introduction
Increasing numbers of caregivers provide support to older adults after surgery, which is associated with stress and negative impacts on their health. Our review questions were:
Methods
The databases searched included PubMed, OVID MEDLINE, OVID PsycINFO, EBSCO CINAHL, OVID EMBASE, Web of Science Core Collection, Wiley Cochrane CENTRAL on February 14, 2024. Studies eligible for inclusion were randomized controlled trial (RCT) or quasi-experimental design with control groups, published in English, Dutch, German, French and Persian, included any unpaid caregiver, and the intervention must include a component specifically designed to meet the caregivers’ needs.
Results
in total 27,845 were screened and 45 full texts were reviewed. Seven RCTs, two pilot RCTS, and four quasi RCTs were included. Only five interventions had any positive impact and included self-management, telehealth, education and a family-centered care model.
Conclusion
Few effective interventions were identified and more engagement with caregivers may identify interventions that better target the caregivers’ needs.
Prospero registration number
CRD42024519637.
{"title":"Interventions to support caregivers of older adults undergoing surgery: A systematic review","authors":"Elham Navab , Nicholas Legacy , Kristen R. Haase , Laura Freeman , Ainslee Smith , Amir Hossein Goudarzian , Ana Patricia Ayala , Valentina Donison , Ailsa Sirois , Farshad Sharifi , Tyler R. Chesney , Camilla Wong , Joanne Callow , Dominque Boswell , Shabbir Alibhai , Martine Puts","doi":"10.1016/j.amjsurg.2025.116226","DOIUrl":"10.1016/j.amjsurg.2025.116226","url":null,"abstract":"<div><h3>Introduction</h3><div>Increasing numbers of caregivers provide support to older adults after surgery, which is associated with stress and negative impacts on their health. Our review questions were:</div></div><div><h3>Methods</h3><div>The databases searched included PubMed, OVID MEDLINE, OVID PsycINFO, EBSCO CINAHL, OVID EMBASE, Web of Science Core Collection, Wiley Cochrane CENTRAL on February 14, 2024. Studies eligible for inclusion were randomized controlled trial (RCT) or quasi-experimental design with control groups, published in English, Dutch, German, French and Persian, included any unpaid caregiver, and the intervention must include a component specifically designed to meet the caregivers’ needs.</div></div><div><h3>Results</h3><div>in total 27,845 were screened and 45 full texts were reviewed. Seven RCTs, two pilot RCTS, and four quasi RCTs were included. Only five interventions had any positive impact and included self-management, telehealth, education and a family-centered care model.</div></div><div><h3>Conclusion</h3><div>Few effective interventions were identified and more engagement with caregivers may identify interventions that better target the caregivers’ needs.</div></div><div><h3>Prospero registration number</h3><div>CRD42024519637.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"242 ","pages":"Article 116226"},"PeriodicalIF":2.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-29DOI: 10.1016/j.amjsurg.2025.116227
Manuel Castillo-Angeles , Cheryl K. Zogg , Molly P. Jarman , Stephanie Nitzschke , Reza Askari , Zara Cooper , Ali Salim , Joaquim M. Havens
Background
Hospital experience measured by geriatric trauma proportion (GTP) is associated with in-hospital mortality among geriatric patients. Our goal was to determine the impact of GTP on long-term survival among older trauma patients.
Methods
This was a retrospective analysis of Medicare inpatient claims (2014–2015) of geriatric trauma patients admitted in Florida. GTP was calculated by dividing the number of geriatric trauma patients by the overall adult trauma volume in each hospital. Hospitals were then categorized into tertiles of GTP. Our main outcome was mortality at 30, 90, 180, and 365 days. Multivariable regression was performed to identify the association between GTP and long-term survival.
Results
We included 65,763 geriatric trauma patients. As compared with hospitals in the lowest tertile, patients treated at the highest tertile were associated with lower mortality at 90 days (OR 0.90, 95%CI 0.82–0.98), 180 days (OR 0.90, 95%CI 0.83–0.97), and 365 days (OR 0.91, 95%CI 0.85–0.98).
Conclusions
Higher GTP is associated with improved long-term outcomes. However, mortality following trauma among geriatric patients continues to increase for 12 months.
{"title":"Hospital experience with geriatric trauma impacts long-term survival","authors":"Manuel Castillo-Angeles , Cheryl K. Zogg , Molly P. Jarman , Stephanie Nitzschke , Reza Askari , Zara Cooper , Ali Salim , Joaquim M. Havens","doi":"10.1016/j.amjsurg.2025.116227","DOIUrl":"10.1016/j.amjsurg.2025.116227","url":null,"abstract":"<div><h3>Background</h3><div>Hospital experience measured by geriatric trauma proportion (GTP) is associated with in-hospital mortality among geriatric patients. Our goal was to determine the impact of GTP on long-term survival among older trauma patients.</div></div><div><h3>Methods</h3><div>This was a retrospective analysis of Medicare inpatient claims (2014–2015) of geriatric trauma patients admitted in Florida. GTP was calculated by dividing the number of geriatric trauma patients by the overall adult trauma volume in each hospital. Hospitals were then categorized into tertiles of GTP. Our main outcome was mortality at 30, 90, 180, and 365 days. Multivariable regression was performed to identify the association between GTP and long-term survival.</div></div><div><h3>Results</h3><div>We included 65,763 geriatric trauma patients. As compared with hospitals in the lowest tertile, patients treated at the highest tertile were associated with lower mortality at 90 days (OR 0.90, 95%CI 0.82–0.98), 180 days (OR 0.90, 95%CI 0.83–0.97), and 365 days (OR 0.91, 95%CI 0.85–0.98).</div></div><div><h3>Conclusions</h3><div>Higher GTP is associated with improved long-term outcomes. However, mortality following trauma among geriatric patients continues to increase for 12 months.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"242 ","pages":"Article 116227"},"PeriodicalIF":2.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-29DOI: 10.1016/j.amjsurg.2025.116230
Chandler Hinson, Jenna Alkhatib, Lamario Williams, Madhushree Zope, Emmanuel A Ameh, Peter Nthumba
{"title":"Navigating the challenges of surgical research in low-and-middle income settings.","authors":"Chandler Hinson, Jenna Alkhatib, Lamario Williams, Madhushree Zope, Emmanuel A Ameh, Peter Nthumba","doi":"10.1016/j.amjsurg.2025.116230","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116230","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116230"},"PeriodicalIF":2.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.amjsurg.2025.116204
Sherene E Sharath, Marie-Claire R Roberts, Ernest J Barthélemy, Danylo Orlov, Panos Kougias
{"title":"How to deploy a study: Key building blocks for maximum impact in surgical health services research.","authors":"Sherene E Sharath, Marie-Claire R Roberts, Ernest J Barthélemy, Danylo Orlov, Panos Kougias","doi":"10.1016/j.amjsurg.2025.116204","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2025.116204","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"116204"},"PeriodicalIF":2.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}