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Captioning Brought to You By … A call for operating room accessibility 为您带来的标题是…呼吁手术室无障碍
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-12-01 DOI: 10.1016/j.amjsurg.2025.116762
Brian M. Carter
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引用次数: 0
Dedicated bedside assistance improves operative efficiency in robotic colorectal surgery: A retrospective comparative study 专用床边辅助提高机器人结直肠手术的手术效率:一项回顾性比较研究
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-28 DOI: 10.1016/j.amjsurg.2025.116760
Mustafa Oruc, Tyler Cross, Salih Karahan, Anna Spivak, Metincan Erkaya, Anuradha Bhama, Scott Steele, Emre Gorgun

Background

The effect of dedicated bedside assistance on the outcomes of robotic colorectal surgery has not been clearly established. This study evaluated whether dedicated bedside assistance (DBA) improves the operative efficiency and overall surgical performance.

Method

A retrospective analysis was conducted on 148 consecutive robotic proctectomy and sigmoidectomy cases performed by a single expert colorectal surgeon between 2021 and 2024. Cases were compared based on the presence or absence of a dedicated bedside assistant. Both intraoperative metrics and postoperative outcomes were analyzed.

Results

The presence of DBA was associated with significantly reduced operation, console, and non-console times in rectal procedures, with efficiency gains observed across most clinical subgroups. Workflow improvements were also observed in sigmoid surgeries despite similar total operative durations.

Conclusion

The implementation of a DBA markedly enhances intraoperative efficiency in robotic colorectal surgery. This benefit is most pronounced in technically demanding rectal procedures, where skilled bedside support can significantly streamline workflow and reduce console time.
专门的床边辅助对机器人结直肠手术结果的影响尚未明确确定。本研究评估了专用床边辅助(DBA)是否能提高手术效率和整体手术效果。方法回顾性分析2021年至2024年由一名专业结直肠外科医生连续实施的148例机器人直肠切除术和乙状结肠切除术病例。根据是否有专门的床边助理来比较病例。分析术中指标和术后结果。结果DBA的存在与直肠手术、控制和非控制时间的显著减少有关,在大多数临床亚组中观察到效率的提高。尽管总手术时间相似,但乙状结肠手术的工作流程也有所改善。结论应用DBA可显著提高机器人结直肠手术的术中效率。这种好处在技术要求苛刻的直肠手术中最为明显,其中熟练的床边支持可以显着简化工作流程并减少控制台时间。
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引用次数: 0
Resected intrahepatic cholangiocarcinoma: Is adjuvant chemotherapy associated with improved overall survival? 切除肝内胆管癌:辅助化疗是否与总生存率提高相关?
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1016/j.amjsurg.2025.116761
R.L. Wolansky , M.A. Kendall , T. Zander , J. Sujka , P.C. Kuo , M.S. Baker

Background

Recent randomized trials evaluating survival benefit to adjuvant chemotherapy (AC) in cholangiocarcinoma evaluate heterogeneous populations including patients with gallbladder cancer, extrahepatic, and intrahepatic cholangiocarcinoma (ICCA). The efficacy of AC in ICCA remains undefined.

Methods

We queried the National Cancer Database for patients undergoing resection of localized ICCA between 2006 and 2017. Patients receiving AC were 1:1 propensity score matched for age, sex, race, comorbidities, insurance, stage, radiation, and resection margin to those undergoing resection alone. Kaplan-Meier (KM) methods were used to compare 5-year overall survival (OS) patterns for matched cohorts.

Results

1312 patients underwent resection of ICCA; 489 (37.3 ​%) received AC. 411 patients undergoing AC were successfully matched to 411 undergoing surgery alone. Median OS was 40.8 months for patients treated with AC versus 32.0 months for those undergoing resection alone (p ​= ​0.151).

Conclusions

AC offers limited potential benefit to patients with resected ICCA.
背景:最近评估胆管癌辅助化疗(AC)的生存获益的随机试验评估了异质人群,包括胆囊癌、肝外胆管癌和肝内胆管癌(ICCA)患者。AC在ICCA中的疗效尚不明确。方法:我们查询了2006年至2017年期间接受局部ICCA切除术的患者的国家癌症数据库。接受AC的患者在年龄、性别、种族、合并症、保险、分期、放疗和切除边缘方面与单独接受切除的患者的倾向评分匹配为1:1。Kaplan-Meier (KM)方法用于比较匹配队列的5年总生存期(OS)模式。结果:1312例患者行ICCA切除术;489例(37.3%)接受了AC。411例接受AC的患者与411例单独接受手术的患者成功匹配。AC治疗患者的中位OS为40.8个月,而单纯切除患者的中位OS为32.0个月(p = 0.151)。结论:AC对ICCA切除患者的潜在益处有限。
{"title":"Resected intrahepatic cholangiocarcinoma: Is adjuvant chemotherapy associated with improved overall survival?","authors":"R.L. Wolansky ,&nbsp;M.A. Kendall ,&nbsp;T. Zander ,&nbsp;J. Sujka ,&nbsp;P.C. Kuo ,&nbsp;M.S. Baker","doi":"10.1016/j.amjsurg.2025.116761","DOIUrl":"10.1016/j.amjsurg.2025.116761","url":null,"abstract":"<div><h3>Background</h3><div>Recent randomized trials evaluating survival benefit to adjuvant chemotherapy (AC) in cholangiocarcinoma evaluate heterogeneous populations including patients with gallbladder cancer, extrahepatic, and intrahepatic cholangiocarcinoma (ICCA). The efficacy of AC in ICCA remains undefined.</div></div><div><h3>Methods</h3><div>We queried the National Cancer Database for patients undergoing resection of localized ICCA between 2006 and 2017. Patients receiving AC were 1:1 propensity score matched for age, sex, race, comorbidities, insurance, stage, radiation, and resection margin to those undergoing resection alone. Kaplan-Meier (KM) methods were used to compare 5-year overall survival (OS) patterns for matched cohorts.</div></div><div><h3>Results</h3><div>1312 patients underwent resection of ICCA; 489 (37.3 ​%) received AC. 411 patients undergoing AC were successfully matched to 411 undergoing surgery alone. Median OS was 40.8 months for patients treated with AC versus 32.0 months for those undergoing resection alone (p ​= ​0.151).</div></div><div><h3>Conclusions</h3><div>AC offers limited potential benefit to patients with resected ICCA.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"252 ","pages":"Article 116761"},"PeriodicalIF":2.7,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive predictive value of the Afirma gene sequencing classifier for evaluation of the indeterminate thyroid nodule: An institutional experience 阳性预测价值的Afirma基因测序分类器评估不确定甲状腺结节:一个机构的经验。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1016/j.amjsurg.2025.116759
Sarah Lyon , Abby Turza , Santhi Ganesan , Christopher R. McHenry

Background

The purpose of this study was to determine the positive predictive value (PPV) and false positive (FP) rate for the Afirma Gene Sequencing Classifier (GSC).

Methods

The GSC was analyzed in patients with indeterminate thyroid nodules (ITN). True positive (TP), FP and PPV were determined and were correlated with pathology.

Results

From June 2023–January 2025, 75 ITN were evaluated with the GSC and it was suspicious for cancer in 21 (28 ​%); 15 patients with 16 suspicious nodules underwent thyroidectomy. There were 7 ​TP and 9 FP results for a PPV of 44 ​%. The final pathology was papillary cancer 6 and oncocytic carcinoma 1 with TP GSC and follicular/oncocytic adenoma 4, follicular nodule 2, NIFTP 2 and Hashimoto thyroiditis 1 with FP GSC.

Conclusions

A PPV of 44 ​% for the GSC has implications for the extent of surgery and for reducing overtreatment of patients with ITN.
背景:本研究的目的是确定Afirma基因测序分类器(GSC)的阳性预测值(PPV)和假阳性(FP)率。方法:对不确定甲状腺结节(ITN)患者的GSC进行分析。测定真阳性(TP)、FP和PPV,并与病理相关。结果:从2023年6月至2025年1月,75例ITN经GSC评估,其中21例(28%)怀疑为癌症;15例16个可疑结节行甲状腺切除术。PPV为44%时,有7例TP和9例FP结果。最终病理为乳头状癌6和嗜酸细胞癌1伴TP型GSC,滤泡/嗜酸细胞腺瘤4、滤泡结节2、NIFTP 2和桥本甲状腺炎1伴FP型GSC。结论:GSC的PPV为44%,对手术范围和减少ITN患者的过度治疗具有重要意义。
{"title":"Positive predictive value of the Afirma gene sequencing classifier for evaluation of the indeterminate thyroid nodule: An institutional experience","authors":"Sarah Lyon ,&nbsp;Abby Turza ,&nbsp;Santhi Ganesan ,&nbsp;Christopher R. McHenry","doi":"10.1016/j.amjsurg.2025.116759","DOIUrl":"10.1016/j.amjsurg.2025.116759","url":null,"abstract":"<div><h3>Background</h3><div>The purpose of this study was to determine the positive predictive value (PPV) and false positive (FP) rate for the Afirma Gene Sequencing Classifier (GSC).</div></div><div><h3>Methods</h3><div>The GSC was analyzed in patients with indeterminate thyroid nodules (ITN). True positive (TP), FP and PPV were determined and were correlated with pathology.</div></div><div><h3>Results</h3><div>From June 2023–January 2025, 75 ITN were evaluated with the GSC and it was suspicious for cancer in 21 (28 ​%); 15 patients with 16 suspicious nodules underwent thyroidectomy. There were 7 ​TP and 9 FP results for a PPV of 44 ​%. The final pathology was papillary cancer 6 and oncocytic carcinoma 1 with TP GSC and follicular/oncocytic adenoma 4, follicular nodule 2, NIFTP 2 and Hashimoto thyroiditis 1 with FP GSC.</div></div><div><h3>Conclusions</h3><div>A PPV of 44 ​% for the GSC has implications for the extent of surgery and for reducing overtreatment of patients with ITN.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"252 ","pages":"Article 116759"},"PeriodicalIF":2.7,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of non-obstructed gastric volvulus: Repair during the index hospitalization vs early elective setting. 非梗阻性胃扭转的结局:指数住院期间的修复与早期选择设置。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1016/j.amjsurg.2025.116758
A Laykova, D Scheeres, G Zambito, A Banks-Venegoni

Introduction: There is a current gap in literature regarding the appropriate timing of non-emergent repair for a resolved obstructing gastric volvulus. This study aims to evaluate outcomes related to hiatal hernia repair (HHR) during the index hospitalization versus early outpatient repair, with the assumption that outpatient repair will result in better outcomes.

Methods: This study included HHR data from 2017 to 2022. The primary outcome assessed overall morbidity using the Clavien-Dindo classification among various secondary outcomes.

Results: A total of 25 patients were included. There was no difference in morbidity between groups (p ​= ​0.66). In the outpatient group, 3 patients re-volvulized prior to repair and the LOS post repair was statistically longer in the inpatient group (2.5 days vs 1 day, p ​= ​0.0172).

Conclusion: Our findings demonstrate that definitive HHR following resolved obstructing gastric volvulus can be safely performed during the index hospitalization, without increase in morbidity, which may be preferred for this patient population.

导读:目前关于解决梗阻胃扭转的非紧急修复时机的文献存在空白。本研究旨在评估住院期间裂孔疝修复(HHR)与早期门诊修复的相关结果,并假设门诊修复会产生更好的结果。方法:本研究纳入2017 - 2022年HHR数据。主要结局采用Clavien-Dindo分级在各种次要结局中评估总体发病率。结果:共纳入25例患者。两组间发病率差异无统计学意义(p = 0.66)。门诊组修复前再容积3例,住院组修复后LOS更长(2.5天vs 1天,p = 0.0172)。结论:我们的研究结果表明,在指数住院期间,解决梗阻性胃扭转后的最终HHR可以安全地进行,而不会增加发病率,这可能是该患者群体的首选。
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引用次数: 0
Diagnostic value of molecular testing for evaluating thyroid nodules greater than 4 centimeters 分子检测对大于4厘米甲状腺结节的诊断价值
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-27 DOI: 10.1016/j.amjsurg.2025.116755
Niranjna Swaminathan , ZhiXing Song , Christopher Wu , Ramsha Akhund , Jessica Fazendin , Brenessa Lindeman , Herbert Chen , Andrea Gillis

Background

Molecular testing (MT) aids in reducing unnecessary thyroidectomy for indeterminate thyroid nodules, primarily due to its high negative predictive value (NPV). However, its reliability in large nodules (≥4 ​cm), which carry a higher malignancy risk, remains unclear.

Methods

We performed a retrospective study of patients with thyroid nodules ≥4 ​cm who underwent fine-needle aspiration (FNA) at a tertiary care center from 2015 to 2023. Cytology was categorized using the Bethesda system. Molecular results (Afirma GEC and GSC) were matched with surgical pathology. Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was classified as malignant.

Results

A total of 231 patients were included (mean age 52 ​± ​16 years; 69.7 ​% female). The median nodule size was 5.0 ​cm (IQR: 4.4–5.8). Malignancy was identified in 28.1 ​% of cases. Malignancy rates by Bethesda category were 4.3 ​% (Bethesda II), 33.8 ​% (III), and 50.0 ​% (IV), all Bethesda V and VI nodules were malignant. Among 96 patients with Bethesda III or IV cytology, 79 (82.3 ​%) underwent MT, 30 with GEC and 47 with GSC. GEC yielded 91.7 ​% sensitivity, 33.3 ​% specificity, and NPV of 85.7 ​%. GSC showed 88.9 ​% sensitivity, 58.6 ​% specificity, and NPV of 89.5 ​%. Malignancy occurred in 40.0 ​% (GEC) and 38.3 ​% (GSC) of tested nodules. False negatives included anaplastic carcinoma, oncocytic carcinoma, and NIFTP. Mutation testing revealed malignancy in 41.4 ​% of BRAF-negative and 44.8 ​% of RET/PTC-negative patients.

Conclusion

Molecular testing in nodules ≥4 ​cm may underestimate malignancy risk. Clinicians should interpret benign MT results in this subgroup with caution.
分子检测(MT)有助于减少不确定甲状腺结节的不必要的甲状腺切除术,主要是由于其高阴性预测值(NPV)。然而,对于恶性肿瘤风险较高的大结节(≥4cm),其可靠性尚不清楚。方法回顾性分析2015年至2023年在某三级医疗中心接受细针穿刺(FNA)治疗的甲状腺结节≥4 cm患者。细胞学分类采用Bethesda系统。分子结果(Afirma GEC和GSC)与手术病理相符。具有乳头状核特征的非侵袭性甲状腺滤泡性肿瘤(NIFTP)被归类为恶性肿瘤。结果共纳入231例患者,平均年龄52±16岁,女性占69.7%。中位结节大小为5.0 cm (IQR: 4.4-5.8)。恶性肿瘤占28.1%。Bethesda分型的恶性率分别为4.3% (Bethesda II型)、33.8% (Bethesda III型)和50.0% (Bethesda IV型),所有Bethesda V型和VI型结节均为恶性。在96例Bethesda III或IV细胞学检查患者中,79例(82.3%)接受了MT, 30例接受了GEC, 47例接受了GSC。GEC的敏感性为91.7%,特异性为33.3%,NPV为85.7%。GSC的敏感性为88.9%,特异性为58.6%,NPV为89.5%。恶性结节发生率为40.0% (GEC)和38.3% (GSC)。假阴性包括间变性癌、嗜瘤细胞癌和NIFTP。突变检测显示,41.4%的brf阴性患者和44.8%的RET/ ptc阴性患者为恶性肿瘤。结论≥4 cm结节的分子检测可能低估了肿瘤的恶性风险。临床医生应谨慎解释该亚组的良性MT结果。
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引用次数: 0
Diagnostic localization techniques in Primary hyperparathyroidism: Is PET Choline the new gold standard? 原发性甲状旁腺功能亢进的定位诊断技术:PET胆碱是新的金标准吗?
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-26 DOI: 10.1016/j.amjsurg.2025.116754
Niranjna Swaminathan, Sanya Nathani, Andrea Gillis, Sophie Dream, Brenessa Lindeman, Herbert Chen, Peter J Abraham
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引用次数: 0
Patients with primary hyperparathyroidism who required three or more parathyroidectomies: Could this be prevented? 原发性甲状旁腺功能亢进症患者需要三次或三次以上的甲状旁腺切除术:这种情况可以预防吗?
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-26 DOI: 10.1016/j.amjsurg.2025.116753
Alexandra Savage, Rachael Caretti, Hector Caceres, Madeleine Obuya, Zhixing Song, Sanajana Balachandra, Jessica Fazendin, Brenessa Lindeman, Andrea Gillis, Sophie Dream, Herbert Chen
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引用次数: 0
U.S. mortality in abdominal surgical emergencies: Comparative analysis of obesity-associated vs overall deaths (1999–2020) 美国腹部外科急诊死亡率:1999-2020年肥胖相关死亡与总体死亡的比较分析
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-25 DOI: 10.1016/j.amjsurg.2025.116735
Haneen Kamran , Muhammad Umar Bhatti , Sameen Tahira , Umm E. Aimen Minhas , Farah Khan , Muhammad Ahsan Asif , Azeem Khalid , Juaquito Jorge , Kashaf Sherafgan

Background

Obesity increases mortality risk in emergency abdominal surgery patients, yet large-scale, population-level analyses remain scarce.

Methods

This study analyzed U.S. mortality trends (1999–2020) from the CDC WONDER database, assessing mortality both overall and in obese patients with acute abdominal surgical emergencies (ASE) using ICD-10 codes. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were calculated.

Results

Obesity-related ASE AAMR rose significantly from 2.05 to 5.5 per million, with a marked increase post-2018 (APC ​= ​23.42). Mortality was higher in women but increased faster in men in the obesity group in contrast to higher ASE related mortality in males overall. Significant racial disparities were noted, with obesity related ASE mortality highest among non-Hispanic American Indians. Regionally, the South exhibited the steepest mortality increase.

Conclusion

Rising trends in obesity-related mortality in abdominal surgical emergencies, showing racial and regional disparities, call for targeted interventions.
背景:肥胖会增加急诊腹部手术患者的死亡风险,但大规模的、人群水平的分析仍然很少。方法:本研究分析了来自CDC WONDER数据库的美国死亡率趋势(1999-2020),使用ICD-10代码评估急性腹部外科急诊(ASE)肥胖患者的总体死亡率和死亡率。计算年龄调整死亡率(AAMRs)和年变化百分比(APCs)。结果:肥胖相关ASE AAMR从2.05 /百万显著上升至5.5 /百万,2018年后显著上升(APC = 23.42)。在肥胖组中,女性死亡率较高,但男性的死亡率增加得更快,这与男性总体上较高的ASE相关死亡率形成了对比。显著的种族差异被注意到,非西班牙裔美国印第安人中肥胖相关的ASE死亡率最高。从区域来看,南方的死亡率增幅最大。结论:腹部外科急诊肥胖相关死亡率呈上升趋势,显示出种族和地区差异,需要有针对性的干预。
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引用次数: 0
Hashtags and healing: Leveraging reddit for holistic ostomy care 标签和治疗:利用reddit进行整体造口护理。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-11-25 DOI: 10.1016/j.amjsurg.2025.116722
Ava Herzog , Mei Xing G. Zuo , Ritika Patel , Jonathan Canete , Edward Lee
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引用次数: 0
期刊
American journal of surgery
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