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A chance to cut is a chance to cure 切割的机会就是治疗的机会。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.115995
Eleanor A. Fallon MD, Sarah B. Fisher MD, MS (Assistant Professor)
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引用次数: 0
When physician supply does not meet patient demand: A looming epidemic in vascular and renal care for a community with the highest incidence of end-stage renal disease in the United States 当医生供应无法满足患者需求时:在一个美国终末期肾病发病率最高的社区,血管和肾病护理领域即将出现流行病。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.115906
Valentine S. Alia , Toluwani Akinpelu , Aaron Dadzie , Shuaibahmed Arab , Robert Sanchez , Aaron Silva , Christian D. Cerecedo Lopez , Daniel Albo

Background

South Texas and the Rio Grande Valley (RGV) are medically underserved-communities near the Texas-Mexico border with the highest incidence of end-stage renal disease (ESRD) in the nation, and a shortage of available full-time equivalent (FTE) specialty-physicians.

Methods

Data on the incidence/prevalence of ESRD and workforce projections on vascular-surgeons and nephrologists were collected from the United States Renal Data System and Texas Department of State Health Services. We then merged data from both datasets to identify population-specific healthcare-trends.

Results

Texas had the highest rates of ESRD from 2016 to 2020, with its border regions leading the state. By 2032, vascular-surgery and nephrology are projected to have the 1st and 4th worst physician-shortages in the state respectively, with the percentage of these FTE specialty-physicians available to meet the need of the RGV ranging from 42.3 to 58.4 ​%.

Conclusions

The RGV is experiencing increased rates of ESRD, while having a paradoxical-decline in specialty-physicians available to provide adequate care.
背景:得克萨斯州南部和里奥格兰德河谷(RGV)靠近得克萨斯州和墨西哥边境,是医疗服务不足的社区,其终末期肾病(ESRD)发病率居全美之首,但现有相当于全职(FTE)的专科医师却十分短缺:方法:我们从美国肾脏数据系统和得克萨斯州卫生服务部收集了有关 ESRD 发病率/流行率的数据以及血管外科医生和肾病医生的劳动力预测数据。然后,我们合并了这两个数据集的数据,以确定特定人群的医疗趋势:结果:从 2016 年到 2020 年,得克萨斯州的 ESRD 患病率最高,其中边境地区居首位。预计到 2032 年,血管外科和肾脏科的医生短缺率将分别位居全州第一和第四位,这些全职专科医师可满足 RGV 需求的比例从 42.3% 到 58.4% 不等:结论:RGV 的 ESRD 患病率在不断上升,而可提供适当医疗服务的专科医师却在不断减少。
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引用次数: 0
Trust issues in the operating room: What does sex have to do with it? 手术室中的信任问题:性别与此有何关系?
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.116046
Alison A. Smith MD, PhD, FACS
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引用次数: 0
NET guidelines for white patients may not fit Asian patients NET针对白人患者的指南可能不适合亚洲患者。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.116116
Ahmer Irfan , Katherine E. McElroy , Rui Zheng-Pywell , Andrea Gillis , Sushanth Reddy , Clayton Yates , Herbert Chen , J. Bart Rose

Introduction

Pancreatic neuroendocrine tumors (pNETs) are slow growing, malignant tumors that show different survival outcomes by race. Current size-based guidelines were largely developed in White patients. Our aim was to investigate tumor size and incidence of lymph node metastasis (LNM) between White and Asian pNET patients to evaluate generalizability of established guidelines.

Methods

Using the National Cancer Database (NCDB), we conducted a multi-institutional analysis of patients with low grade, resected, nonfunctional, sporadic, non-metastatic pNETs. Chi-squared tests were implemented to determine correlation between PTS and LMN incidence as well as race and LMN incidence. A logistic regression model was utilized to determine correlation between LMN, tumor size, and race. Overall survival was assessed using the Kaplan-Meier method.

Results

A total of 4977 pNET patients (205 Asian and 4772 White) were included in our analysis. Asian patients presented with smaller tumors (3.0 ​cm vs 3.9 ​cm, p ​= ​0.029) but when grouped by size, there was no difference in the distribution (p ​= ​0.77). White patients demonstrated a higher incidence of lymph node metastasis at presentation compared to Asian patients (27 ​% vs 19 ​%, p ​= ​0.013), a higher likelihood of an R0 resection (95.3 ​% vs. 89.3 ​%, p ​< ​0.0001).
Within both populations, tumor size (<2 ​cm, 2–3 ​cm, and ≥3 ​cm) positively correlated with incidence of LNM (11.5 ​%, 24.6 ​%, and 39.1 ​%). No difference of LNM was seen between racial cohorts at PTS <3 ​cm, however, Asian patients were less likely to exhibit LNM at PTS ≥3 ​cm (28.2 ​% and 39.5 ​%, p ​= ​0.04). Overall survival was not significantly different between racial groups (p ​= ​0.92).

Conclusion

Size based surgical resection guidelines for pancreatic neuroendocrine tumors based on a predominantly White patient population may not be generalizable to the Asian population. Within this population, we found the risk of lymph node metastasis did not increase at similar rates with increasing primary tumor size.
胰腺神经内分泌肿瘤(pNETs)是一种生长缓慢的恶性肿瘤,其生存结局因种族而异。目前基于尺寸的指南主要是针对白人患者制定的。我们的目的是研究白人和亚裔pNET患者的肿瘤大小和淋巴结转移(LNM)发生率,以评估既定指南的普遍性。方法:使用国家癌症数据库(NCDB),我们对低级别,切除,无功能,散发性,非转移性pNETs患者进行了多机构分析。采用卡方检验确定PTS与LMN发病率以及种族与LMN发病率之间的相关性。采用logistic回归模型确定LMN、肿瘤大小和种族之间的相关性。采用Kaplan-Meier法评估总生存率。结果:我们的分析共纳入4977例pNET患者(205例亚洲人,4772例白人)。亚洲患者肿瘤较小(3.0 cm vs 3.9 cm, p = 0.029),但按大小分组时,分布无差异(p = 0.77)。与亚洲患者相比,白人患者在发病时表现出更高的淋巴结转移发生率(27%对19%,p = 0.013), R0切除的可能性更高(95.3%对89.3%,p)结论:以白人患者为主的胰腺神经内分泌肿瘤手术切除指南可能无法推广到亚洲人群。在这一人群中,我们发现淋巴结转移的风险并没有随着原发肿瘤大小的增加而增加。
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引用次数: 0
Long-term oncological outcomes of minimally invasive versus open gastrectomy for cancer 微创与开放式胃切除术治疗癌症的长期肿瘤预后。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.116134
Francesco Abboretti , Laura Didisheim , Hugo Teixeira Farinha , Markus Schäfer , Styliani Mantziari

Background

Although laparoscopy is widely used in oncologic digestive surgery, many centers are still reluctant to replace open surgery for gastric cancer treatment, especially in advanced disease. The aim of this study was to assess long-term survival and recurrence in patients after laparoscopic (LG) versus open (OG) oncological gastrectomy, in a tertiary reference center.

Methods

All consecutive patients with gastric adenocarcinoma undergoing curative gastrectomy between December 2007 and December 2021 were retrospectively analyzed. Clinico-pathological characteristics, survival and recurrence were compared among LG, OG or converted (CoG) patients. The ×2 test was used for categorical variables and the Mann-Whitney U test for continuous ones. Survival was assessed with the Kaplan-Meier method and log-rank test, as well as a multivariable Cox regression analysis.

Results

Among 156 included patients, 49 (31.4 ​%) were in the LG group, 93 (59.6 ​%) in the OG group, and 14 (9 ​%) in the CoG group. Baseline demographics were similar among the groups. R0 resection rates were 75.5 ​% in LG, 80.6 ​% in OG, and 64.3 ​% in CoG (p ​= ​0.489). Open surgery was associated with a higher mean lymph node yield (28.4 ​± ​11.6) compared to LG (22.8 ​± ​9.7) and CoG (26.5 ​± ​12.3, p ​= ​0.036). Severe postoperative complications were higher in the CoG group (64.3 ​% CoG versus 29 ​% OG, 32.7 ​% LG, p ​= ​0.035). The CoG group had a significantly inferior disease-free survival (p ​= ​0.012 vs OG, p ​= ​0.003 vs LG; 53.3 ​% OG, 62.7 ​% LG and 28.1 ​% CoG) although overall survival was similar (57.1 ​% OG, 62.7 ​% LG and 32.7 ​% CoG, all p ​> ​0.005).

Conclusions

Laparoscopic gastrectomy, while associated with a lower lymph node yield, provides similar overall survival rates compared to open surgery. Conversion to open surgery was associated with higher major postoperative morbidity and inferior disease-free survival.
背景:虽然腹腔镜在肿瘤消化外科手术中应用广泛,但许多中心仍不愿意取代开放手术治疗胃癌,特别是在晚期疾病中。本研究的目的是在三级参考中心评估腹腔镜(LG)与开放式(OG)肿瘤胃切除术后患者的长期生存率和复发率。方法:回顾性分析2007年12月至2021年12月连续行根治性胃切除术的所有胃腺癌患者。比较LG、OG和转归(CoG)患者的临床病理特征、生存率和复发率。分类变量采用×2检验,连续变量采用Mann-Whitney U检验。生存率评估采用Kaplan-Meier法和log-rank检验,以及多变量Cox回归分析。结果:156例患者中,LG组49例(31.4%),OG组93例(59.6%),CoG组14例(9%)。各组的基线人口统计数据相似。R0切除率LG为75.5%,OG为80.6%,CoG为64.3% (p = 0.489)。开放手术的平均淋巴结清扫率(28.4±11.6)高于LG(22.8±9.7)和CoG(26.5±12.3,p = 0.036)。CoG组术后严重并发症发生率较高(CoG组64.3%,OG组29%,LG组32.7%,p = 0.035)。CoG组无病生存期明显低于OG组(p = 0.012, p = 0.003);53.3% OG, 62.7% LG和28.1% CoG),尽管总生存率相似(57.1% OG, 62.7% LG和32.7% CoG,均p < 0.05)。结论:腹腔镜胃切除术,虽然与较低的淋巴结率相关,但与开放手术相比,提供了相似的总生存率。转为开放手术与较高的术后主要发病率和较差的无病生存率相关。
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引用次数: 0
Surgery/non-surgery-based strategies for invasive locally-advanced non-small cell lung cancer in the era of precision medicine 精准医学时代侵袭性局部晚期非小细胞肺癌的手术/非手术治疗策略
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.116132
Min Wang , Bin Wang , Xianyan Chen , Ting Mei , Xuexi Yang , Qiang Luo , Feifei Na , Youling Gong

Background

Treatments for invasive T4 non-small cell lung cancer (NSCLC) tumors have been traditionally individualized and often require multidisciplinary team (MDT) evaluation. Advances in precision medicine may open up new opportunities for these patients.

Methods

This retrospective cohort study, using the Surveillance, Epidemiology, and End Results (SEER) database, identified T4N0-3M0 NSCLC patients with central structure invasion from 2010 to 2020. Precision medicine has progressed in three periods: 2010–2014 (targeted therapy), 2015–2017 (initial immunotherapy), and 2018–2020 (latest immunotherapy). We utilized Propensity Score Matching (PSM) to control confounding factors and competing risk regression models to evaluate cancer-specific survival (CSS).

Results

A total of 9,106 cases were matched after PSM. For all populations, the median overall survival (OS) significantly increased with the advancement of precision medicine: 23.0 months in Period I (95 ​% CI: 22.0–25.0), 28.0 months in Period II (95 ​% CI: 26.0–31.0), and not reached (NR) in Period III (95 ​% CI: 30.0 – NR). Multivariate analysis also revealed a sequential survival improvement from Period I to III (p ​< ​0.001). Surgery-based treatment yielded the longest median OS at 46.0 months (95 ​% CI: 43.0–49.0, p ​< ​0.001), compared with chemoradiotherapy, chemotherapy alone and radiation alone. Surgery-based treatment has also yielded the best survival in three precision medicine eras, in both N0-1 and N2-3 categories. After analyzing CSS, the results above remained consistent. The survival following chemoradiotherapy and chemotherapy alone has seen significant and progressive enhancements across the three eras of precision medicine. There were no significant survival differences between Periods I and II among surgery-based patients, but a slight improvement trend was noted in Period III.

Conclusion

This retrospective study indicated that as precision medicine for NSCLC evolved, personalized treatment strategies supported by effective MDT led to survival improvement. Notably, for invasive stage III patients, surgery-based strategies have consistently shown substantial benefits across all the periods, irrespective of the N stage. The integration of perioperative therapies to enhance surgical feasibility, especially the latest immunotherapy, holds particular promise for further survival benefits.
背景:浸润性T4非小细胞肺癌(NSCLC)肿瘤的治疗传统上是个体化的,通常需要多学科团队(MDT)评估。精准医疗的进步可能会为这些患者带来新的机会。方法:本回顾性队列研究使用监测、流行病学和最终结果(SEER)数据库,确定了2010年至2020年中心结构侵犯的T4N0-3M0 NSCLC患者。精准医学的发展经历了2010-2014年(靶向治疗)、2015-2017年(初始免疫治疗)和2018-2020年(最新免疫治疗)三个阶段。我们使用倾向得分匹配(PSM)来控制混杂因素和竞争风险回归模型来评估癌症特异性生存(CSS)。结果:PSM后共匹配9106例。对于所有人群,中位总生存期(OS)随着精准医学的进步而显著增加:第一阶段为23.0个月(95% CI: 22.0-25.0),第二阶段为28.0个月(95% CI: 26.0-31.0),第三阶段未达到(NR) (95% CI: 30.0 - NR)。多变量分析还显示,从第1期到第3期(p 0-1和N2-3类别),患者的生存率依次提高。在分析CSS后,上述结果保持一致。在精准医学的三个时代,单纯放化疗和化疗后的生存率显著提高。手术患者I期和II期生存率无显著差异,但III期生存率略有改善。结论:本回顾性研究表明,随着NSCLC精准医学的发展,有效MDT支持的个性化治疗策略可提高患者的生存率。值得注意的是,对于侵袭性III期患者,手术为基础的策略在所有时期都一致显示出实质性的益处,无论N期如何。围手术期治疗的整合提高了手术的可行性,尤其是最新的免疫治疗,对进一步的生存益处有着特别的希望。
{"title":"Surgery/non-surgery-based strategies for invasive locally-advanced non-small cell lung cancer in the era of precision medicine","authors":"Min Wang ,&nbsp;Bin Wang ,&nbsp;Xianyan Chen ,&nbsp;Ting Mei ,&nbsp;Xuexi Yang ,&nbsp;Qiang Luo ,&nbsp;Feifei Na ,&nbsp;Youling Gong","doi":"10.1016/j.amjsurg.2024.116132","DOIUrl":"10.1016/j.amjsurg.2024.116132","url":null,"abstract":"<div><h3>Background</h3><div>Treatments for invasive T<sub>4</sub> non-small cell lung cancer (NSCLC) tumors have been traditionally individualized and often require multidisciplinary team (MDT) evaluation. Advances in precision medicine may open up new opportunities for these patients.</div></div><div><h3>Methods</h3><div>This retrospective cohort study, using the Surveillance, Epidemiology, and End Results (SEER) database, identified T<sub>4</sub>N<sub>0-3</sub>M<sub>0</sub> NSCLC patients with central structure invasion from 2010 to 2020. Precision medicine has progressed in three periods: 2010–2014 (targeted therapy), 2015–2017 (initial immunotherapy), and 2018–2020 (latest immunotherapy). We utilized Propensity Score Matching (PSM) to control confounding factors and competing risk regression models to evaluate cancer-specific survival (CSS).</div></div><div><h3>Results</h3><div>A total of 9,106 cases were matched after PSM. For all populations, the median overall survival (OS) significantly increased with the advancement of precision medicine: 23.0 months in Period I (95 ​% CI: 22.0–25.0), 28.0 months in Period II (95 ​% CI: 26.0–31.0), and not reached (NR) in Period III (95 ​% CI: 30.0 – NR). Multivariate analysis also revealed a sequential survival improvement from Period I to III (<em>p</em> ​<em>&lt;</em> ​0.001). Surgery-based treatment yielded the longest median OS at 46.0 months (95 ​% CI: 43.0–49.0, <em>p</em> ​<em>&lt;</em> ​0.001), compared with chemoradiotherapy, chemotherapy alone and radiation alone. Surgery-based treatment has also yielded the best survival in three precision medicine eras, in both N<sub>0-1</sub> and N<sub>2-3</sub> categories. After analyzing CSS, the results above remained consistent. The survival following chemoradiotherapy and chemotherapy alone has seen significant and progressive enhancements across the three eras of precision medicine. There were no significant survival differences between Periods I and II among surgery-based patients, but a slight improvement trend was noted in Period III.</div></div><div><h3>Conclusion</h3><div>This retrospective study indicated that as precision medicine for NSCLC evolved, personalized treatment strategies supported by effective <span>MDT</span> led to survival improvement. Notably, for invasive stage III patients, surgery-based strategies have consistently shown substantial benefits across all the periods, irrespective of the N stage. The integration of perioperative therapies to enhance surgical feasibility, especially the latest immunotherapy, holds particular promise for further survival benefits.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 116132"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142816991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive retrospective analysis of the European hernia Society quality of life in patients undergoing abdominal wall reconstruction 欧洲疝气协会对腹壁重建患者生活质量的全面回顾性分析。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.115905
Raul Castañeda-Vozmediano , Bárbara Areces Carrasco , Alejandra López Marsella , Carmen Ahenke Francisco , Joaquín Munoz-Rodriguez , Luis Alberto Blazquez Hernando , Alvaro Robin Valle de Lersundi , Javier Lopez-Monclus , Miguel Angel Garcia-Urena

Introduction

This study aimed to analyze the European Hernia Society Quality of Life (EHS-QoL) in abdominal wall reconstruction by comparing preoperative scores with those at 1 and 2 postoperative years.

Methods

Data from 105 patients with complex incisional hernias were collected preoperatively and at 1 and 2 years postoperatively. Statistical analyses included three ART ANOVA models to compare scores among the three time points and within each time point's items.

Results

The EHS score significantly decreased from preoperative (Mdn ​= ​57) to 1 year (Mdn ​= ​10.5) and 2 years postoperative (Mdn ​= ​8). The most significant changes occurred between preoperative and 1-year measurements, particularly in pain levels during activities and limitations in heavy labor and activities outside the home.

Conclusion

Patients' quality of life notably improved at 1 year post-surgery, with some reaching near-maximum levels, and this improvement was generally sustained or increased at 2 years post-surgery.
简介:本研究旨在分析欧洲疝气协会腹壁重建术的生活质量(EHS-QoL):本研究旨在通过比较术前评分与术后1年和2年的评分,分析欧洲疝气协会(EHS-QoL)在腹壁重建中的生活质量:收集了 105 名复杂切口疝患者的术前、术后 1 年和 2 年的数据。统计分析包括三个 ART 方差分析模型,以比较三个时间点之间和每个时间点项目内的得分:EHS 评分从术前(Mdn = 57)到术后 1 年(Mdn = 10.5)和 2 年(Mdn = 8)均明显下降。最明显的变化发生在术前和术后 1 年的测量之间,尤其是在活动时的疼痛程度以及重体力劳动和外出活动的限制方面:结论:患者的生活质量在术后 1 年得到明显改善,部分患者的生活质量接近最高水平,这种改善在术后 2 年普遍得到维持或提高。
{"title":"Comprehensive retrospective analysis of the European hernia Society quality of life in patients undergoing abdominal wall reconstruction","authors":"Raul Castañeda-Vozmediano ,&nbsp;Bárbara Areces Carrasco ,&nbsp;Alejandra López Marsella ,&nbsp;Carmen Ahenke Francisco ,&nbsp;Joaquín Munoz-Rodriguez ,&nbsp;Luis Alberto Blazquez Hernando ,&nbsp;Alvaro Robin Valle de Lersundi ,&nbsp;Javier Lopez-Monclus ,&nbsp;Miguel Angel Garcia-Urena","doi":"10.1016/j.amjsurg.2024.115905","DOIUrl":"10.1016/j.amjsurg.2024.115905","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to analyze the European Hernia Society Quality of Life (EHS-QoL) in abdominal wall reconstruction by comparing preoperative scores with those at 1 and 2 postoperative years.</div></div><div><h3>Methods</h3><div>Data from 105 patients with complex incisional hernias were collected preoperatively and at 1 and 2 years postoperatively. Statistical analyses included three ART ANOVA models to compare scores among the three time points and within each time point's items.</div></div><div><h3>Results</h3><div>The EHS score significantly decreased from preoperative (Mdn ​= ​57) to 1 year (Mdn ​= ​10.5) and 2 years postoperative (Mdn ​= ​8). The most significant changes occurred between preoperative and 1-year measurements, particularly in pain levels during activities and limitations in heavy labor and activities outside the home.</div></div><div><h3>Conclusion</h3><div>Patients' quality of life notably improved at 1 year post-surgery, with some reaching near-maximum levels, and this improvement was generally sustained or increased at 2 years post-surgery.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 115905"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disparities in timely surgery among Asian American women with breast cancer 美国亚裔女性乳腺癌患者在及时手术方面的差异。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.115928
Yuan-Hsin Chen , Ya-Wen Chen , David C. Chang , Tawakalitu O. Oseni

Background

We investigated the likelihood of timely surgery for breast cancer patients among diverse Asian subgroups.

Methods

We analyzed the National Cancer Database from 2010 to 2019 and included White and Asian women diagnosed with stage I-III breast cancer. Patients with multiple cancers, patients who received chemotherapy, and those diagnosed and treated at different hospitals were excluded. The primary outcome was timely surgery within 8 weeks of diagnosis. Race was the primary independent variable. Asian Americans were stratified by geography.

Results

A total of 716,701 women were analyzed, with 3.5% Asians. Delayed surgery was experienced by 13.2% of women. Adjusted analysis indicated no difference in receiving timely surgery between all Asians and Whites. However, Southeast Asians were less likely to undergo timely surgery compared to Whites (OR 0.75, 95% CI 0.67–0.84).

Conclusions

Variations among Asian ethnicities emphasize the need to explore treatment patterns to address disparities in breast cancer care.
背景我们调查了不同亚裔亚群中乳腺癌患者及时手术的可能性:我们分析了 2010 年至 2019 年的全国癌症数据库,纳入了诊断为 I-III 期乳腺癌的白人和亚裔女性。排除了患有多种癌症的患者、接受过化疗的患者以及在不同医院诊断和治疗的患者。主要结果是确诊后 8 周内及时手术。种族是主要的自变量。亚裔美国人按地域分层:共分析了 716,701 名妇女,其中亚裔占 3.5%。13.2%的女性经历过手术延迟。调整后的分析表明,所有亚洲人和白人在及时接受手术方面没有差异。然而,与白人相比,东南亚人接受及时手术的可能性较低(OR 0.75,95% CI 0.67-0.84):结论:亚裔之间的差异强调了探索治疗模式以解决乳腺癌护理差异的必要性。
{"title":"Disparities in timely surgery among Asian American women with breast cancer","authors":"Yuan-Hsin Chen ,&nbsp;Ya-Wen Chen ,&nbsp;David C. Chang ,&nbsp;Tawakalitu O. Oseni","doi":"10.1016/j.amjsurg.2024.115928","DOIUrl":"10.1016/j.amjsurg.2024.115928","url":null,"abstract":"<div><h3>Background</h3><div>We investigated the likelihood of timely surgery for breast cancer patients among diverse Asian subgroups.</div></div><div><h3>Methods</h3><div>We analyzed the National Cancer Database from 2010 to 2019 and included White and Asian women diagnosed with stage I-III breast cancer. Patients with multiple cancers, patients who received chemotherapy, and those diagnosed and treated at different hospitals were excluded. The primary outcome was timely surgery within 8 weeks of diagnosis. Race was the primary independent variable. Asian Americans were stratified by geography.</div></div><div><h3>Results</h3><div>A total of 716,701 women were analyzed, with 3.5% Asians. Delayed surgery was experienced by 13.2% of women. Adjusted analysis indicated no difference in receiving timely surgery between all Asians and Whites. However, Southeast Asians were less likely to undergo timely surgery compared to Whites (OR 0.75, 95% CI 0.67–0.84).</div></div><div><h3>Conclusions</h3><div>Variations among Asian ethnicities emphasize the need to explore treatment patterns to address disparities in breast cancer care.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 115928"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroidectomy outcomes in admitted patients are indeed worse than for outpatents: Providers must now acknowledge and respond 入院患者的甲状腺切除术效果确实比门诊患者差:医疗服务提供者现在必须认识到这一点并做出回应。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.115992
Aimee N. Di Marco
{"title":"Thyroidectomy outcomes in admitted patients are indeed worse than for outpatents: Providers must now acknowledge and respond","authors":"Aimee N. Di Marco","doi":"10.1016/j.amjsurg.2024.115992","DOIUrl":"10.1016/j.amjsurg.2024.115992","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 115992"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the disparities within: Why we need to disaggregate data for Asian women with breast cancer 揭示内部差异:为什么我们需要对亚洲女性乳腺癌患者的数据进行分类?
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2025-02-01 DOI: 10.1016/j.amjsurg.2024.116013
Angelena Crown, Amanda L. Kong
{"title":"Unveiling the disparities within: Why we need to disaggregate data for Asian women with breast cancer","authors":"Angelena Crown,&nbsp;Amanda L. Kong","doi":"10.1016/j.amjsurg.2024.116013","DOIUrl":"10.1016/j.amjsurg.2024.116013","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"240 ","pages":"Article 116013"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
American journal of surgery
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