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Chronic Pain Self-Management for Health Equity in Limited Resource Settings: The Rwandan Experience. 慢性疼痛自我管理在有限资源环境下的健康公平:卢旺达的经验。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007953
Gaston Nyirigira, Emile Twagirumukiza, Jean de Dieu Singirankabo, Kara L Neil
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引用次数: 0
A New General Anesthetic BTTE: Physical Properties, Hypnotic and Hemodynamic Effects in Rats, and Effects on GABA and NMDA Receptors Expressed in Frog Oocytes. 新型全麻BTTE:对大鼠的物理特性、催眠和血流动力学影响,以及对蛙卵母细胞表达的GABA和NMDA受体的影响。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007955
Robert J Brosnan, Shane Austin, Joseph F Antognini
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引用次数: 0
Dexmedetomidine's Effect on Delirium, Cognitive Dysfunction, and Sleep: More Questions Than Answers. 右美托咪定对谵妄、认知功能障碍和睡眠的影响:问题多于答案。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007963
Mark L van Zuylen
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引用次数: 0
The Critical Role of Hospital Identifiers in Evaluating Failure-to-Rescue Disparities. 医院标识符在评估抢救失败差异中的关键作用。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007959
Yasmine Tameze, Kenneth T Shelton
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引用次数: 0
Cause-Based Classification of Intraoperative Adverse Events. 术中不良事件的病因分类。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007962
Clara Pereira
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引用次数: 0
Evaluating Perspectives on Empathy in Anesthesiology Trainees: A Mixed-Methods Study of Pre-Anesthesia Encounters. 评估麻醉学受训者的共情观点:麻醉前遭遇的混合方法研究。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007919
Oluwakemi Tomobi, Catherine Gouge, Alyssa Brashear, Daniel Totzkay, Fei Chen, Julie Huffmyer, David Scalzo, Edward C Nemergut, Rebekah Guillow

Background: Empathy is a crucial part of the therapeutic relationship. Inadequate patient-physician communication can result in misunderstanding, reduced patient satisfaction, poor compliance with recommended interventions, and increased malpractice risk. Despite its importance, empathy among anesthesiology trainees remains under explored. This observational study used validated tools to evaluate trainee empathy in the pre-anesthesia setting from different perspectives.

Methods: Participating anesthesiology trainees were observed as they conducted pre-anesthesia patient encounters. First, they completed self-evaluations using the Jefferson Scale of Empathy (JSE) and the Resident Wellness Scale. Additionally, patients who were 18 years or older completed the Jefferson Scale of Patient Perceptions of Physician Empathy (JSPPPE) after their pre-anesthesia interview with the anesthesia trainee. A non-anesthesiologist physician evaluated the interactions between patients and anesthesia trainees with the Jefferson Empathy Scale for Observers (JSEO). Quantitative analyses of closed questions (including empathy scales) included descriptive statistics, correlations, and multivariable linear regression analysis. Open-ended questions were analyzed using thematic analysis.

Results: Twenty-four trainees completed 151 observed patient pre-anesthesia encounters with at least 5 observations per trainee. There was a modest, negative correlation between average time (seconds) in patient interaction and trainee wellness (r = -0.421, P = .041), and a moderate negative correlation between the trainee empathy subdomain "walking in the patient's shoes" and year in training (r = -0.451, P = .021). Male trainees spent more time during the consultation (mean time ± SD = 396 ± 80 seconds vs. 323 ± 50 seconds, P = .035) and had higher mean ratings from patients (JSPPPE rating 33.1 ± 3.00 vs 32.2 ± 3.00, P = .020) than female trainees. On multivariable analysis, predictors of highest empathy ratings were male gender (JSPPPE: P = .022) and the year of training (JSE: P = .013; JSEO: p =0.023). Thematic analysis of patient and observer comments suggests a discrepancy in perceived empathy, with patients less likely to perceive positive behaviors as empathetic, but an emphasis on importance of information delivered in the pre-anesthesia encounter.

Conclusion: Patients found male trainees and trainees earlier in training to display higher levels of empathy which differed from observer ratings. Qualitative evaluation may offer insights into our understanding of patient-perceived empathy in anesthesiology trainees. The discrepancy between patient, trainee, and observer ratings suggests that perceived empathy in anesthesiology pre-anesthesia interviews may be driven by different factors than in other specialties, particularly information exchange and efficiency of communication.

背景:共情是治疗关系的重要组成部分。医患沟通不足会导致误解,降低患者满意度,对推荐干预措施的依从性差,并增加医疗事故风险。尽管移情很重要,但麻醉学受训者之间的移情仍有待探索。本观察性研究使用经过验证的工具,从不同角度评估麻醉前情境下受训者的同理心。方法:对参与麻醉培训的学员进行麻醉前患者接触时的观察。首先,他们使用杰弗逊共情量表(JSE)和居民健康量表完成自我评估。此外,18岁或以上的患者在麻醉前与麻醉培训生面谈后完成了杰弗逊患者对医生共情感知量表(JSPPPE)。一名非麻醉科医师用杰弗逊观察者共情量表(JSEO)评估患者与麻醉学员之间的互动。封闭问题(包括共情量表)的定量分析包括描述性统计、相关性和多变量线性回归分析。开放式问题采用主题分析法进行分析。结果:24名受训者完成了151次麻醉前观察,每位受训者至少有5次观察。与患者互动的平均时间(秒)与受训人员健康之间存在适度的负相关(r = -0.421, P = 0.041),受训人员共情子域“换位思考”与培训时间之间存在适度的负相关(r = -0.451, P = 0.021)。男性学员会诊时间更长(平均时间±SD = 396±80秒比323±50秒,P = 0.035),患者平均评分(JSPPPE评分33.1±3.00比32.2±3.00,P = 0.020)高于女性学员。在多变量分析中,共情评分最高的预测因子是男性性别(JSPPPE: P = 0.022)和培训年份(JSE: P = 0.013; JSEO: P =0.023)。对患者和观察者评论的专题分析表明,在感知共情方面存在差异,患者不太可能将积极行为视为共情,但强调在麻醉前遇到的信息传递的重要性。结论:患者发现男性受训者和较早接受训练的受训者表现出较高的共情水平,与观察者的评分不同。定性评估可以为我们理解麻醉受训者的患者感知共情提供见解。患者、受训者和观察员评分之间的差异表明,麻醉前访谈中感知到的共情可能受到与其他专业不同的因素驱动,尤其是信息交换和沟通效率。
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引用次数: 0
National Study of Milestone Evaluation Differences by Gender and Race in Anesthesiology Residency Training. 全国麻醉学住院医师培训中里程碑性评价的性别和种族差异研究。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007927
Ting Sun, Yoon Soo Park, Fei Chen, Nikki Wilkinson, Pedro Tanaka

Background: Competency-based medical education (CBME) relies on criterion-referenced assessments to track residents' progression toward independent practice. The Accreditation Council for Graduate Medical Education (ACGME) Milestones serve as a structured framework to evaluate trainee performance, yet concerns have been raised about potential demographic differences in Milestone ratings. This study examined gender and race differences in Milestone ratings among anesthesiology residents.

Methods: We conducted a retrospective cohort study of 4997 residents from 141 anesthesiology programs graduating between 2017 and 2019. Milestone data from ACGME were linked with the Association of American Medical Colleges demographic data. Three-level mixed-effects models were conducted to estimate the differences in baseline Milestone ratings and growth trajectories, and predict marginal means of ratings at graduation by gender and race across 25 subcompetencies.

Results: At baseline, no significant differences in Milestone ratings were observed by gender or race. However, underrepresented minorities in medicine (URiM) residents demonstrated slower growth in ratings over time, resulting in significantly lower scores across all subcompetencies at graduation. Gender-based growth trajectories over time did not differ significantly between male and female residents, but by graduation, women received significantly lower ratings in 7 of 25 subcompetencies, primarily in patient care (PC) and medical knowledge (MK) competencies. The largest differences were observed in MK-1. Effect sizes for other subcompetencies were smaller, suggesting limited practical differences overall.

Conclusions: These findings highlight that comparable Milestones ratings at baseline, yet modest but cumulative differences over time may lead to meaningful differences at graduation, particularly in MK-1 for URiM residents.

背景:以能力为基础的医学教育(CBME)依靠标准参考评估来跟踪住院医师走向独立执业的进展。研究生医学教育认证委员会(ACGME)的里程碑是评估实习生表现的结构化框架,但人们对里程碑评级中潜在的人口差异提出了担忧。本研究考察了麻醉科住院医师在里程碑评分方面的性别和种族差异。方法:对2017年至2019年毕业的141个麻醉学专业4997名住院医师进行回顾性队列研究。ACGME的里程碑数据与美国医学院协会的人口统计数据相关联。采用三级混合效应模型来估计基线里程碑评分和增长轨迹的差异,并根据性别和种族预测25个子能力在毕业时评分的边际均值。结果:基线时,未观察到性别或种族在里程碑评分上的显著差异。然而,随着时间的推移,医学中代表性不足的少数民族(URiM)居民表现出较慢的评分增长,导致毕业时所有次级能力的得分明显较低。随着时间的推移,基于性别的成长轨迹在男性和女性住院医师之间没有显着差异,但到毕业时,女性在25个子能力中的7个子能力中获得显着较低的评分,主要是患者护理(PC)和医学知识(MK)能力。其中MK-1差异最大。其他子胜任力的效应量较小,表明总体上的实际差异有限。结论:这些发现强调了基线时可比的里程碑评分,但随着时间的推移,适度但累积的差异可能导致毕业时有意义的差异,特别是在URiM居民的MK-1中。
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引用次数: 0
Use of Three-Dimensional Spine Reconstruction to Guide Paramedian Thoracic Epidural Insertion: A Proof-of-Concept Study. 使用三维脊柱重建指导辅助胸椎硬膜外置入:一项概念验证研究。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-03 DOI: 10.1213/ANE.0000000000007928
Ruth Shaylor, Vladimir Verenkin, Michael Peer, Orie Sella, Carolyn Weiniger, Barak Cohen
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引用次数: 0
The Myth of Depth of Anesthesia Monitors: When a "Normal" Bispectral Index Does not Mean What You Think It Means. 麻醉深度监测器的神话:当一个“正常”的双谱指数并不意味着你想的那样。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-02 DOI: 10.1213/ANE.0000000000007934
Paul S García, Peter A Goldstein
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引用次数: 0
Exogenous Sex Hormones and Postoperative Nausea and Vomiting Risk in Transgender Patients. 外源性性激素与跨性别患者术后恶心呕吐风险的关系。
IF 3.8 2区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-02 DOI: 10.1213/ANE.0000000000007929
Leonard J Soloniuk, Jasmine Sran, Christopher Baker, Andrew Kim, Blake Han, Sallie Canumay, Daniel Novak, Ashish C Sinha, Gary Stier

Background: Postoperative nausea and vomiting (PONV) remain a significant consideration in perioperative care; however, the incidence and risk factors of PONV in transgender patients are poorly understood. This study investigated the rates of PONV in transgender patients receiving gender-affirming hormone therapy (GAHT) compared to cisgender patients. We postulate that exogenous testosterone GAHT reduces the risk of PONV while exogenous estrogen GAHT increases the risk of PONV.

Methods: This retrospective cohort study was conducted using the TriNetX database. Patients were divided into 2 groups: transgender and cisgender. Separate analyses were performed for hysterectomies (transgender male [assigned female at birth, AFAB] versus cisgender female), orchiectomies (transgender female [assigned male at birth, AMAB] versus cisgender male), and augmentation mammoplasties (transgender female [AMAB] versus cisgender female). Propensity score matching was performed for age, race, and ethnicity (White, Black, Hispanic, or Latino), which were treated as social and demographic variables as recorded in the database, nicotine dependence, and tobacco use. The primary outcome was the administration of a rescue antiemetic, defined as droperidol, promethazine, dimenhydrinate, metoclopramide, and prochlorperazine, on the day of or day following surgery.

Results: Following hysterectomy, there was a significant difference in the risk of rescue antiemetic use between transgender males (AFAB) taking testosterone GAHT (62.11%, 1031 of 1660) and cisgender females (65.90%, 1094 of 1660) (P = .0227). Following orchiectomy, there was a significant difference in the risk of rescue antiemetic use between transgender females (AMAB) taking estrogen GAHT (51.15%, 445 of 870) and cisgender males (36.78%, 320 of 870) (P < .0001). Following augmentation mammoplasty, there was a significant difference in the risk of rescue antiemetic use between transgender females (AMAB) taking estrogen GAHT (53.29%, 356 of 668) and cisgender females (43.71%, 292 of 668) (P = .0005).

Conclusions: Transgender female (AMAB) patients on estrogen GAHT required rescue antiemetics more often than cisgender males and cisgender females after orchiectomies and augmentation mammoplasties. Transgender male (AFAB) patients on testosterone GAHT required rescue antiemetics less often than cisgender females after hysterectomies. These findings underscore the need for individualized perioperative care and antiemetic prophylaxis to promote equitable anesthetic care for transgender patients. This study's retrospective design limits causal inference and is subject to coding errors and residual confounding. Prospective studies with detailed perioperative and hormonal data are needed to validate these findings and clarify how the timing, dosage, and duration of GAHT influence PONV risk.

背景:术后恶心和呕吐(PONV)仍然是围手术期护理的重要考虑因素;然而,对跨性别患者PONV的发生率和危险因素了解甚少。本研究调查了接受性别确认激素治疗(GAHT)的跨性别患者与顺性别患者的PONV发生率。我们假设外源性睾丸激素可降低PONV的风险,而外源性雌激素可增加PONV的风险。方法:采用TriNetX数据库进行回顾性队列研究。患者分为跨性别和顺性别两组。对子宫切除术(变性男性[出生时被指定为女性,AFAB]与顺性女性)、睾丸切除术(变性女性[出生时被指定为男性,AMAB]与顺性男性)和隆胸手术(变性女性[AMAB]与顺性女性)进行了单独的分析。对年龄、种族和民族(白人、黑人、西班牙裔或拉丁裔)进行倾向评分匹配,将其作为数据库中记录的社会和人口变量、尼古丁依赖和烟草使用进行处理。主要结局是在手术当天或术后给予抢救止吐剂,定义为哌啶醇、异丙嗪、苯海明、甲氧氯普胺和丙氯拉嗪。结果:子宫切除术后,使用睾酮GAHT的跨性别男性(AFAB)与使用顺性女性(65.90%,1094 / 1660)抢救止吐药的风险差异有统计学意义(P = 0.0227)。睾丸切除术后,跨性别女性(AMAB)使用雌激素- GAHT(51.15%, 870例中的445例)与顺性别男性(36.78%,870例中的320例)使用救急止呕吐药的风险差异有统计学意义(P < 0.0001)。隆胸术后使用雌激素- GAHT的跨性别女性(AMAB)(53.29%, 668例中有356例)与使用无性别女性(43.71%,668例中有292例)使用救助性止吐药的风险差异有统计学意义(P = 0.0005)。结论:变性女性(AMAB)患者在睾丸切除术和隆胸手术后,比顺性男性和顺性女性更需要紧急止吐药。跨性别男性(AFAB)患者在子宫切除术后需要紧急止吐药的情况比顺性别女性少。这些发现强调了个性化围手术期护理和止吐预防的必要性,以促进跨性别患者的公平麻醉护理。本研究的回顾性设计限制了因果推理,并受到编码错误和残留混淆的影响。需要有详细围手术期和激素数据的前瞻性研究来验证这些发现,并阐明GAHT的时机、剂量和持续时间如何影响PONV风险。
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Anesthesia and analgesia
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