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Study the anti – inflammatory effect of Stevia rebaudiana sweetness in vitro 研究甜菊糖的体外抗炎作用
Pub Date : 2021-07-22 DOI: 10.29350/qjps.2021.26.4.1404
Meison Abdulbary, Albasheer Ammar, Muhanad Mohammed, Wafaa Yousif, Suaad Lateef Ibrahim
Because of the high rates of diabetes, overweight disorders and fatness, the need and interest in finding alternatives to sugar has increased, especially in the industrial sector in parallel with reducing the daily intake of sugar by human. The idea of this research was developed to identify the active ingredients which include in the  plant aqueous extract of Stevia rebaudiana. Chemical examination showed the glycosides and phenolic compounds presence of in the Stevia rebaudiana plant. The effect of Stevia rebaudiana leaves products aqueous extract as anti-inflammation  measured in vitro with two procedures , The repression of protein denaturation and hemolysis stimulated by heating and results showed Stevia rebaudiana efficiency with compared to typical medicine (Aspirin) and negative control groups.
由于糖尿病、超重失调和肥胖的高发率,特别是在减少人类每日糖摄入量的同时,工业部门对寻找糖的替代品的需求和兴趣有所增加。本研究的目的是鉴定甜菊叶植物水提物中的有效成分。化学鉴定表明甜菊属植物中含有甙类和酚类化合物。采用两种方法对甜菊叶产品水提物的体外抗炎作用进行了测定,结果表明甜菊叶产品水提物对加热刺激下的蛋白质变性和溶血的抑制作用优于典型药物(阿司匹林)和阴性对照组。
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引用次数: 0
Invariants of Uniform Conjugacy on Uniform Dynamical System 一致动力系统的一致共轭不变量
Pub Date : 2021-07-19 DOI: 10.29350/qjps.2021.26.4.1386
Alaa Abboud, I. Khadim
  In this paper, we present some important dynamical concepts on uniform space such as the uniform minimal systems, uniform shadowing, and strong uniform shadowing. We explain some definitions and theorems such as definition uniform expansive, weak uniform expansive, uniform generator, and the proof of the theorems for them. We prove that if  be a homeomorphism on a compact uniform space  then  has uniform shadowing if and only if has uniform shadowing, so if  has strong uniform shadowing if and only if has strong uniform shadowing. We also show that  and  be two uniform homeomorphisms on compact uniform spaces  and , if  is a uniform conjugacy from  to , then . Besides some other results.
本文给出了一致空间中一些重要的动力学概念,如一致极小系统、一致阴影和强一致阴影。给出了一致膨胀、弱一致膨胀、一致生成的定义和定理,并给出了这些定理的证明。证明了紧致一致空间上的同胚当且仅当有均匀阴影时具有均匀阴影,因此当且仅当具有强均匀阴影时具有强均匀阴影。我们还证明了和是紧一致空间上的两个一致同胚,如果是到的一致共轭,那么。除了一些其他的结果。
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引用次数: 0
a Biochemical Assessment as Markers for Diagnosis and Evaluation Hepatitis B Virus (HBV) 生化评价作为诊断和评价乙型肝炎病毒(HBV)的标志物
Pub Date : 2021-07-19 DOI: 10.29350/qjps.2021.26.4.1359
Moatasem Alsalih, R. E. Abed, S. Samsudin
Abstract This paper summarizes assessment biochemical markers of the development of hepatitis B viruses (HBV), in which any possible connection between certain biochemical parameters and chronic hepatitis was identified. Liver function tests are helpful in diagnosing liver disease and dysfunction, assessing severity, tracking treatment, and determining prognosis. According to the findings of biochemical studies, chronic patients have higher levels of ALP, GPT, GOT, and TSB than carriers. The rise in liver enzymes strongly indicates hepatocellular damage, despite the fact that ALP, GPT, GOT, and TSB levels in the carrier group were all within normal parameters as compared to the reference group. Testing liver function in terms of protein level, albumin, and globulin, the concentration of protein profiles in chronic patients is clearly decreasing as compared to the carrier group. In severe or long-lasting liver disease, the significant decreasing profile of serum proteins is evident in some conditions, the release of tumor necrosis factor hampers the synthesis of albumin, however, induce the synthesis of the acute phase response, hypoalbuminemia is multifactorial, while the hepatic synthesis of albumin is decreased in liver disease.
摘要本文综述了乙型肝炎病毒(hepatitis B virus, HBV)发展的生化指标评估,发现了某些生化指标与慢性肝炎之间可能存在的联系。肝功能检查有助于诊断肝脏疾病和功能障碍,评估严重程度,跟踪治疗和确定预后。生化研究发现,慢性患者ALP、GPT、GOT、TSB水平均高于携带者。尽管与对照组相比,携带者组的ALP、GPT、GOT和TSB水平均在正常范围内,但肝酶升高强烈提示肝细胞损伤。根据蛋白质水平、白蛋白和球蛋白检测肝功能,慢性患者的蛋白质谱浓度与携带者组相比明显下降。在严重或长期肝病中,血清蛋白在某些情况下明显下降,肿瘤坏死因子的释放阻碍白蛋白的合成,但诱导急性期反应的合成,低白蛋白血症是多因素的,而肝病中白蛋白的肝脏合成减少。
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引用次数: 2
Study the levels of cytokines (IL-12 , IFN-γ) and human Proflin-1 (PFN-1) 研究细胞因子(IL-12, IFN-γ)和人蛋白-1 (PFN-1)的水平
Pub Date : 2021-07-19 DOI: 10.29350/qjps.2021.26.4.1352
H. Hadi, R. A. Kadhim, R. T. Al-Mammori
Abstract       Toxoplasma gondii an intracellular parasite infected large proportion of the world population, but mostly without visible clinical signs in immunocompetent patients. The present study was performed to determined the levels of cytokines (IL-12 , IFN-γ) and human proflin-1 (PFN-1) in the sera of 125 aborted women as case group and 30 healthy women (15 non pregnant and 15 pregnant women) as control groups in Women's and children Hospital in Al-Qadisiyah province from December / 2015 till March / 2016, Five ml of venous blood sample was obtained from each woman under sterile condition. Serum samples were positive for antibodies specific toxoplasmosis IgG and IgM. It was estimated levels of cytokines and profilin1 in these serums and significant increasing showed up in concentration interleukin 12 (IL-12) and profilin-1(PFN-1) and low in the concentration of interferon gamma (IFN-γ) at probability (0.05) in compare with control group that ensure their role in immune response against the parasite. Keywords: Toxoplasma gondii, cytokines (IL-12 , IFN-γ) and human proflin-1 (PFN-1)  
刚地弓形虫是一种细胞内寄生虫,在世界人口中感染的比例很大,但在免疫功能正常的患者中大多没有明显的临床症状。本研究测定了2015年12月至2016年3月在Al-Qadisiyah省妇幼医院的125名流产妇女(病例组)和30名健康妇女(15名未怀孕妇女和15名怀孕妇女)血清中细胞因子(IL-12、IFN-γ)和人蛋白-1 (PFN-1)的水平,在无菌条件下,每名妇女取静脉血5 ml。血清特异性弓形虫病IgG和IgM抗体阳性。与对照组相比,白细胞介素12 (IL-12)和profilin-1(PFN-1)浓度显著升高(0.05),干扰素γ (IFN-γ)浓度显著降低(0.05),从而确定了它们在抗寄生虫免疫应答中的作用。关键词:刚地弓形虫,细胞因子(IL-12, IFN-γ),人蛋白-1 (PFN-1)
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引用次数: 0
Synthesis, Characterization of Thiazolidin-4-one, Oxazolidin-4-one and Imidazolidin-4-one Derivatives from 6-Amino-1,3-dimethyluracil and evaluation of their Antioxidant and Antimicrobial Agent 6-氨基-1,3-二甲基尿嘧啶衍生物噻唑烷-4-酮、恶唑烷-4-酮和咪唑烷-4-酮的合成、表征及其抗氧化和抗菌性能评价
Pub Date : 2021-07-17 DOI: 10.29350/qjps.2021.26.4.1346
H. Al-Adhami, S. Al-Majidi
In this study, a new series of 6-amino-1,3-dimethyluracil derivative with 6-(3-substituted N-benzylidene)-1,3-dimethyl pyrimidine-2,4-dione-6-yl derivatives which were synthesized by using one pot synthesis. The reaction of 6-amino-1,3-dimethyluracil and different aromatic aldehyde in ethanol yielded Schiff bases (1-6). In the subsequent step reaction of Schiff bases )1-6) with 2-mercaptoacetic acid, 2-chloroacetic acid and 2-amino acetic acidn in Tetrahydrofuran yielded five membered heterocyclic rings of 6-amino-1,3-dimethyluracil derivative which includes: 2,3-thiazolidin-4-one (7-12), 2,3-oxazolidin-5-one (13-18), 2,3-imidazolidin-4-one (19-24) derivatives. The structures of newly synthesized compounds were confirmed by their physicochemical and spectral means FTIR, 1HNMR and 13CNMR. The synthesized compounds were evaluated in vitro for antioxidant and antimicrobial activities against four types of bacteria and four types of fungi
本研究采用一锅法合成了一系列新的6-(3-取代n -苄基)-1,3-二甲基嘧啶-2,4-二酮-6-基衍生物-6-氨基-1,3-二甲基尿嘧啶衍生物。6-氨基-1,3-二甲基尿嘧啶与不同芳香醛在乙醇中反应生成席夫碱(1-6)。席夫碱(1-6)与2-巯基乙酸、2-氯乙酸和2-氨基乙酸在四氢呋喃中反应得到5元杂环6-氨基-1,3-二甲基尿嘧啶衍生物,包括:2,3-噻唑烷-4- 1(7-12)、2,3-恶唑烷-5- 1(13-18)、2,3-咪唑烷-4- 1(19-24)衍生物。新合成化合物的结构通过FTIR、1HNMR和13CNMR等理化和光谱手段得到了证实。对合成的化合物进行了体外抗氧化和抑菌活性评价
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引用次数: 2
Applying Some Indices for Soil Pollution Assessment in Northern Industrial Area from Erbil Governorate 埃尔比勒省北部工业区土壤污染评价指标的应用
Pub Date : 2021-07-17 DOI: 10.29350/qjps.2021.26.4.1385
N. Khudhur, Sidra Qubad Yassin, A. Hassan, Mortatha Nawzad Omar
Soil pollution by some heavy metals including: Cr, Mn, Fe, Ni, Cu, Zn, As, Mo, Cd and Pb from northern industrial area of Erbil City was assessed. The contamination indices including: geoaccumulation (Igeo), contamination factor (CF), enrichment factor (EF), degree of contamination (Cdeg), pollution load index (PLI) and element contamination index (ECI) were applied to assess soil pollution in Erbil North Industrial area at three sites (for both surface and sub-surface soils). Maximum Fe value 34243.6 ppm was recorded in sub-surface soil (site 2). Maximum values 265.4, 248.8, 98.23 and 397.45 ppm were recorded for Cr, Ni, Cu and Zn at sub-surface soil (site 3). Whereas, maximum values of 22.52, 5.36, 23.9, 6.12 and 65.67 ppm were recorded for As, Mo, Ag, Cd and Pb at surface soil (site 3). Results of analysed heavy metals for soil Cr, Mn, Fe, Ni, Cu, Zn, As, Mo, Ag, Cd and Pb have shown that the studied sites were severely contaminated with Cd, so the maximum detected Cd concentration was 6.12 ppm in surface soil (300 meters away from the industrial area). The soil pollution in the studied area was classified as moderate to strong surface and sub-surface soil contamination. Behavioral toxicity experiment showed slight growth effect on Lepidium sativum L.
对埃尔比勒市北部工业区土壤中Cr、Mn、Fe、Ni、Cu、Zn、As、Mo、Cd、Pb等重金属的污染进行了评价。应用地质累积(Igeo)、污染因子(CF)、富集因子(EF)、污染程度(Cdeg)、污染负荷指数(PLI)和元素污染指数(ECI)等污染指数对埃尔比勒北部工业区3个样点(表层和次表层土壤)的土壤污染进行了评价。最大Fe值34243.6 ppm是记录在地下土壤(网站2)。最大值265.4,248.8,98.23和397.45 ppm都记录了铬、镍、铜和锌在地下土壤(网站3)。然而,最大值为22.52,5.36,23.9,6.12和65.67 ppm的记录,密苏里州,Ag)、Cd和Pb在表层土壤(网站3)。分析的结果为土壤重金属铬、锰、铁、镍、铜、锌、,密苏里州,Ag)、Cd和Pb研究表明,网站被严重污染的Cd,因此,在距离工业区300米的表层土壤中检测到的最大Cd浓度为6.12 ppm。研究区土壤污染程度可分为中重度表层和次表层土壤污染。行为毒性试验表明,对枸杞有轻微的生长影响。
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引用次数: 0
Batch fermentation and Simultaneous Saccharification and Fermentation (SSF) processes by Meyerozyma Guilliermondii Strain F22 and Saccharomyces cerecvisae for xylitol and bioethanol co-production 吉列蒙地Meyerozyma Guilliermondii菌株F22和酿酒酵母分批发酵和同时糖化发酵(SSF)工艺共同生产木糖醇和生物乙醇
Pub Date : 2021-07-17 DOI: 10.29350/qjps.2021.26.4.1347
Dr.Fawzia Shalsh, Dhoha Kadeem Nagimm, Muhammad Abdul Alrheem, Saffa Abedul Alrheem
Recent years have seen an increase in the use of lignocellulosic materials in the development of bioproduct, biorefinery technologies have focused on process integration for the production of different valuable coproducts in order to reduce the overall processing cost. In this study, agricultural wastes from rice straw were used for the co-production of bioethanol and xylitol. Where bioethanol is produced from the cellulosic fraction and xylitol from the hemicellulose fraction after elimination of lignin using chemical pretreatments. The chemical treatment was carried out with diluted acid 2.5% at a 100 °C for 30 minutes , and then exposed the cellulosic fraction of the solid phase resulting from the chemical process to the enzymatic action of the fungus Trichoderma harzianum for releas sugars and fermented at a later stage using  Saccharomyces cerecvisae for bioethanol production in a simultaneous saccharification and fermentation process, The liquid phase hemicellulose fraction  was exposed to action of Meyerozyma guilliermondii strain F22 (Pichia guilliermondii) for xylitol production. Resulting was accomplished yielding maximum concentrations and product yield were 32.6 g/L 0.39g/g and 20.1 g/L, 0.44g/g for bioethanol and xylitol respectively of the total glucose and xylose available in rice straw, the co-production of xylitol with ethanol in an integrated biorefinery would create economic benefits making the overall lignocellulose-based process more cost effective
近年来,在生物产品的开发中,木质纤维素材料的使用有所增加,生物炼制技术侧重于生产不同有价值的副产品的过程集成,以降低总体加工成本。本研究以农业秸秆废弃物为原料,利用秸秆生产生物乙醇和木糖醇。其中生物乙醇由纤维素部分生产,木糖醇由半纤维素部分生产,木质素经化学预处理去除。在100°C下,用2.5%的稀释酸进行30分钟的化学处理,然后将化学过程产生的固相纤维素部分暴露在真菌哈茨木霉的酶促作用下释放糖,并在后期使用酿酒酵母进行发酵,在糖化和发酵的同时生产生物乙醇。将液相半纤维素馏分暴露于吉列蒙地Meyerozyma guilliermondii菌株F22 (Pichia guilliermondii)的作用下生产木糖醇。结果表明,秸秆中总葡萄糖和木糖醇的最大生产浓度和产率分别为32.6 g/L、0.39g/g和20.1 g/L、0.44g/g,木糖醇与乙醇在一体化生物精炼厂中联产将产生经济效益,使整个木质纤维素工艺更具成本效益
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引用次数: 1
Studying Cholesterol and Triglyceride Levels in Some Types of Fish in Salah Al-Din Governorate 研究Salah Al-Din省某些鱼类的胆固醇和甘油三酯水平
Pub Date : 2021-07-17 DOI: 10.29350/qjps.2021.26.4.1409
N. Albassam, Faroq M. Al Habib, S. Hassan
       The study included seven common types of fish in the Iraqi local market in Salah al-Din Governorate / Tikrit, which are (Carasobarbus luteus, Alburnus mossulensis, Cyprinion kais, Chondrostoma regium, Barbus barbulus, Barbus belayewi, Barbus subquincunciatus). The study of cholesterol and triglycerides of these types of fish showed that the cholesterol levels in the experimental fish were (104.55-9.56 -6.37-9.56 -14.88-51.03-15.94) mg/100 g in the mentioned fish, respectively, and the highest level of cholesterol was in the Carasobarbus luteus fish and it reached 104.55 mg /100gm, and the lowest level in Cyprinion kais is 6.37mg/100gm. The study stated the levels of triglycerides are (990 -348 -993.5 -665.9 -703.5 -1355.2-882.2) mg/kg for fish (Carasobarbus luteus, Alburnus mossulensis, Cyprinion kais, Chondrostoma regium, Barbus barbulus, Barbus belayewi, Barbus subquincunciatus) respectively. The highest level of triglycerides is 1355.2 mg/kg. kg in Barbus belayewi fish and the lowest level in Alburnus mossulensis 348 mg/kg.
该研究包括在萨拉赫丁省/提克里特的伊拉克当地市场上常见的7种鱼,它们是(Carasobarbus luteus, Alburnus mossulensis, Cyprinion kais, Chondrostoma regium, Barbus barbulus, Barbus belayewi, Barbus subquincunciatus)。对这些鱼类的胆固醇和甘油三酯的研究表明,实验鱼的胆固醇水平分别为(104.55-9.56 -6.37-9.56 -14.88-51.03-15.94)mg/100g,其中黄斑鱼的胆固醇水平最高,达到104.55 mg/100gm,鲤科鱼最低,为6.37mg/100gm。研究结果表明,鱼(黄斑鱼、mossulensis、Cyprinion kais、regium Chondrostoma、Barbus barbulus、belayewi、quincunciatus)的甘油三酯含量分别为(990 -348 -993.5 -665.9 -703.5 -1355.2-882.2)mg/kg。甘油三酯最高水平为1355.2 mg/kg。以长鳍鲈鱼为最低,为348 mg/kg。
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引用次数: 0
the Study of some histopathological changes occurring in white laboratory mice infected with Cutaneous Leishmaniasis in Al – diwaniyah province, Iraq. 伊拉克Al - diwaniyah省实验室白色小鼠感染皮肤利什曼病的一些组织病理学变化研究。
Pub Date : 2021-07-16 DOI: 10.29350/qjps.2021.26.4.1323
Lubna.A.Al-ibrahimi Edu, Hind Al-shabani, M. Alwan
          Leishmaniasis is caused by an intracellular parasite . It is endemic in Asia, Africa, the Americas, and the Mediterranean region. Worldwide, 1.5 to 2 million new cases occur each year .The histological study of the liver tissue of white laboratory mice (Mus musculus) infected with L. major a parasite showed The presence of severe steatosis of hepatocytes Hepatocyte degeneration, And loss of the radial arrangement of hepatocytes, With heavy infiltration in inflammatory cells, especially phagocytes( Macrophage) with  Hyperplasia and congestion of the bile duct  .  As for histological sections of skin lesions taken from ear , Foot , tail ، were showed epidermal ulcerative , Accompanied by severe leaching of the dermis layer neutrophil ,polymorph lymphocytes ، with hemorrhage of ​​the dermis, with necrosis of the epidermal cells of all skin lesions in the ear, foot and tail.
利什曼病是由细胞内寄生虫引起的。它在亚洲、非洲、美洲和地中海地区流行。在世界范围内,每年有150万至200万例新发病例。对感染L. major a寄生虫的白色实验室小鼠(小家鼠)肝脏组织的组织学研究显示,肝细胞出现严重的脂肪变性,肝细胞的径向排列丧失,炎症细胞,特别是吞噬细胞(巨噬细胞)大量浸润,伴有胆管增生和充血。耳、足、尾皮损组织切片可见表皮溃疡,伴真皮层中性粒细胞、多形淋巴细胞严重浸出,真皮出血,耳、足、尾皮损表皮细胞坏死。
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引用次数: 0
Effect of magnesium oxide nanoparticles on growth and biochemical content of blue-green alga Wollea salina 氧化镁纳米颗粒对蓝绿藻生长及生化含量的影响
Pub Date : 2021-07-16 DOI: 10.29350/qjps.2021.26.4.1396
Haider A. Alghanmi, Zahra K. M. Al-Khazali
The current study aimed to test the blue-green alga Wollea salina on growth in culture media containing different concentrations of magnesium nanoparticles in addition to the control group (free of nanomaterials) in order to find out the effect of those minutes on the algae's physiology by studying their effect on the growth rate and chlorophyll-a Carotenoids, proteins, carbohydrates and fats. The alga under study was classified according to microscopy and based on some taxonomic keys after it was isolated, purified, and then grown in culture medium (BG-11). Three cultures containing three different concentrations of nano-magnesium oxide solution (93.8, 187.5,281.3) mg/L were used to compare that with the growth in the culture medium (control) free of these substances, to be then produced with biomass. For the purpose of ascertaining and knowing the size of the nanoparticles at the nanoscale, the nanocomposites of magnesium oxide were examined by atomic force microscopy (AFM). The height of the molecular assemblies of the magnesium nanoparticles was determined, and the height of the molecular assemblies was 466 nm, with an average particle size of 35 nm. The algae were also photographed with a Scanning Electron Microscopy (SEM) before and after treatment with magnesium nanoparticles, where the pictures showed the presence of morphological changes at the cellular level for these isolates. The growth rate was (0.388) for W. salina at a concentration of (187.5) mg/l of magnesium oxide (MgO NPS), while the results recorded the highest growth rate when the control treatment (without nanomaterials) was (0.507). Representative dyes were also studied, including chlorophyll-a, and the results showed that the highest value of chlorophyll-a at concentration (281.3) mg/l of MgO NPS was (1.068) µg/l. Also, it was noted that the highest value of carotenoid dye was recorded at a concentration of (281.3) mg/l of MgO NPS, which reached (0.992) µg /l. The highest value of protein (23.63) mg/L was recorded at a concentration of (281.3) mg/L of MgO NPS. As for the total carbohydrates, its content was (4.30) mg/L at concentration (281.3) mg/L compared to the control (4.37) mg/L. The results also recorded an increase in the algae's total fat content of( 0.058) g/l at the concentration (281.3) mg/l of MgO NPS compared to the control treatment, which recorded a total fat content of (0.048) g/l). The results of the statistical analysis showed that there were significant differences between the nanocomposites used in the study represented by magnesium in their effect on the physiology of the algae under study, and the control unit (without nanomaterials) at a significant level of p<0.05.
本研究旨在测试蓝绿藻在不含纳米材料的对照组的基础上,在含有不同浓度镁纳米颗粒的培养基中生长,通过研究镁纳米颗粒对藻类生长速率和叶绿素-a类胡萝卜素、蛋白质、碳水化合物和脂肪的影响,来了解这几分钟对藻类生理的影响。对所研究的藻类进行分离纯化,并在BG-11培养基中培养后,根据显微镜和一些分类键进行分类。采用三种不同浓度的纳米氧化镁溶液(93.8、187.5、281.3)mg/L的培养物与不含这些物质的培养基(对照)中的生长情况进行比较,然后用生物量生产。为了在纳米尺度上确定和了解纳米颗粒的大小,采用原子力显微镜(AFM)对氧化镁纳米复合材料进行了检测。测定了镁纳米粒子的分子组装高度,其分子组装高度为466 nm,平均粒径为35 nm。用扫描电子显微镜(SEM)对这些藻类进行了镁纳米颗粒处理前后的照片,照片显示这些分离物在细胞水平上存在形态变化。在氧化镁(MgO NPS)浓度为(187.5)mg/l时,盐藻的生长速率为(0.388),而对照处理(不含纳米材料)的生长速率为(0.507)。结果表明,在MgO NPS浓度为(281.3)mg/l时,叶绿素-a的最高值为(1.068)µg/l。MgO NPS浓度为(281.3)mg/l时,类胡萝卜素染料的含量最高,达到(0.992)µg /l。MgO NPS浓度为(281.3)mg/L时,蛋白质含量最高,为23.63 mg/L。总碳水化合物在浓度为(281.3)mg/L时的含量为(4.30)mg/L,高于对照(4.37)mg/L。MgO NPS浓度为(281.3)mg/l时,藻类总脂肪含量比对照处理(0.048)g/l时增加了0.058 g/l。统计分析结果显示,以镁为代表的纳米复合材料对研究藻类生理的影响与对照单元(不含纳米材料)存在显著差异(p<0.05)。
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引用次数: 0
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Al-Qadisiyah Journal Of Pure Science
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