Annales Academiae Medicae Stetinensis最新文献

Material and methods: This study records the outcomes of the treatment of 21 patients, 19 men and two women, who sustained an amputation of the total of 35 digits (27 fingers and eight thumbs). Eleven patients received replantation or reconstruction maintaining the length of the digit, whereas ten had their digits terminalized.

Results: The results were assessed at a mean of 5 years after injury. Patients with finger stumps had stronger grip than those with replanted digits (72% vs 48% of strength of the healthy hand). Hand function as assessed by quickDASH score (29 vs 33), quality of life as assessed by SF-36 score (63 vs 67) and number of patients experiencing cold sensitivity (7 vs 7) were similar in both groups. Patients after terminalization returned to work significantly earlier than those after replantation or reconstruction (6 vs 12 months).

Conclusions: These results show that - considering function of the hand - replantation or advanced reconstruction offers the patient less benefit than simple terminalization.

Introduction: Perthes disease appears in children and affects hip joints. The proximal head of the femur is damaged, which results in deformation of the femoral ball and loss of its spherical shape. Instant diagnosis and introduction of treatment is crucial for maintaining the femoral head in the hip socket, which facilitates recovery to its spherical shape. To assess the quality of life of patients who have undergone surgical treatment. The factors examined were: state of functioning and occurrence of pain in affected hip joint.

Material and methods: 61 participants underwent the examination. The duration and type of disease were established on the basis of a radiogram. The patients were treated with varus derotation osteotomy in the 2 and 3 degree of the Reinberg scale. A Modified Oxford Hip Score was used to assess the patients' quality of life.

Results: Subjective assessment of the quality of life after recovering from the disease was regarded as very good and good.

Conclusion: According to the patients' own evaluation the disease and the treatment did not affect their everyday life.

Dupuytren's disease is classified as a benign superficial fibromatosis, in which excessive proliferation of myofibroblats and formation of nodules and chords occurs, followed by development of finger contractures. The similarities between Dupuytren's disease and neoplasms were shown at molecular and clinical grounds. The objective of the study was to review of the literature investigating possible relationship between occurrence of Dupuytren's disease and malignancies. Review of the few available papers shows (1) statistically significantly increased malignant neoplasm mortality among men with advanced Dupuytren's disease, comparing to reference population and men with early stage of the disease, (2) statistically significantly increased malignant neoplasm morbidity, mainly related to smoking and alcohol consumption among patients (men and women) operated on for Dupuytren's disease and (3) increased sarcoma of the bone and soft tissue morbidity in patients 5 years after operation for Dupuytren's disease. Some genetical studies show also altered expression of the dehydrogenases ALDH2 and DHDH genes in patients with Dupuytren's disease and with digestive tract malignancies related to alcohol abuse.

Cardiovascular diseases for decades have been and still are the main and current health problem of the Polish society and there are many reasons for these diseases. Hypertension is one of the major risk factors for developing cardiovascular disease. The factors significantly increasing risk the of cardiovascular disease are in addition to high blood pressure, smoking (also passive), high blood fats (cholesterol and its HDL, LDL fractions as well as triglyceride levels, obesity, lack of exercise, diabetes and hereditary features. Other important factors which play an important role are external factors such as e.g. environmental pollution, lifestyle, stress. Prediction of cardiovascular disease should start from the evaluation of the fetal period because low birth weight may be a risk of coronary heart disease, hypertension, obesity or diabetes in adulthood. The authors of the referred tests showed that the level of blood pressure observed during childhood is closely associated with the level of blood pressure in adults and is also dependent on the body weight. Since the issue of the effects of high pressure on the cardiovascular system is inherent in the issue of the metabolic syndrome, it should be mentioned also that another causative factor may be an irregularity in the removal of urine from the body and the amount of insulin. The control of hypertension is a complex problem, at least in view of the wide range of adverse factors affecting the human body: hypertension is often either a constituent of other lesions. Therefore, it is difficult to treat high blood pressure in the strict sense; more often it is a combination therapy based on pharmacology caused for other reasons.

Syphilis is a specific inflammation which is extremely difficult to clearly diagnose in archaeological material. The origin of this disease is unclear. Most proponents hold the view that it comes from America, and that it was transmitted to Europe by sailors travelling with Columbus. In addition to the thesis of the American origin of syphilis is a suggestion that a mild form of syphilis existed in Europe before Columbus' expeditions. This form, until the end of the fifteenth century, began to spread epidemics. In Poland, the first officially reported case of the disease was described in 1495. Today, an increase in the incidence of new cases in Poland and globally can be observed. An increasing number of cases of congenital syphilis in newborns is also noted. This situation in Poland is connected with a change in the law in 2001, according to which only insured persons became entitled to free treatment. In view of the rising tide of the disease, and the appearance of advanced forms of the disease, in 2009 the free diagnosis, treatment, and follow up for all patients with syphilis was restored.

The case of a 62-year-old female patient diagnosed with an extremely rare clinical variant of pemphigoid--nodular pemphigoid, imitating prurigo nodularis, is presented in the paper. In connection with the existence of the typical prurigo nodularis-like appearance in the patient, the diagnosis was maintained for several months. However, because of no response to the treatment and the remarkably chronic course of the disease, the patient was admitted to the Department in order to extend the diagnostics and verify the previous diagnosis. The direct and indirect immunofluorescence examinations performed on the patient enabled the final diagnosis of a rare variant of pemphigoid without typical blisters, and effective treatment was carried out.