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Annales De Dermatologie Et De Venereologie最新文献

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Retrospective evaluation of a multidisciplinary concertation meeting for hidradenitis suppurativa 对化脓性扁桃体炎多学科协调会议的回顾性评估
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.annder.2024.103305
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引用次数: 0
Chronic trophic disorders in cocaine and heroin injectors: A multicenter retrospective observational descriptive study. 可卡因和海洛因注射者的慢性营养障碍:一项多中心回顾性观察描述性研究。
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-09-01 Epub Date: 2024-07-15 DOI: 10.1016/j.annder.2024.103289
C Pruvot, O Carpentier, A Montmureau, C Becquart, C Fievet, O Cottencin, D Staumont-Salle, L Mortier, M Drouard

Aims: To describe the demographic characteristics of heroin and cocaine injectors with chronic injection-related trophic disorders, as well as the clinical and progressive characteristics of these disorders.

Methods: A descriptive, observational, multicenter and retrospective study over the last 15 years. Patients were recruited via a call for cases and by consulting the health data warehouse of the university hospital center.

Results: The population comprised 39 injection drug users, of whom 79.5% were male, with a median age of 41 years. Subjects had numerous co-addictions and 70.5% were infected with hepatitis C virus. Trophic disorders were multiple in some cases: 43.5% of patients had lymphoedema, 87% had ulcers, and 56.5% had injection-related scars. Ulcers were multiple, large, and present for a median of 3 years. They were located on the upper limbs in 32.5% of cases. Ulcers constituted a source of complications in 64.5% of cases and these were infectious in 91% of cases (local, osteoarticular or systemic). During follow-up, 8 patients died and 21.5% of patients requiring ulcer care were lost to follow-up.

Conclusions: This study showed a high rate of complications, particularly infections, of ulcers in injection drug users. Localization of these ulcers to the upper limbs, although rare in the general population, is relatively frequent in this population. Follow-up is difficult and cooperation between dermatologist and addictologist is essential to improve patient care.

目的:描述患有慢性注射相关营养障碍的海洛因和可卡因注射者的人口统计学特征,以及这些障碍的临床和进展特征:这是一项描述性、观察性、多中心和回顾性研究,历时 15 年。研究人员通过病例征集和查询大学医院中心的健康数据仓库招募患者:研究对象包括 39 名注射毒品使用者,其中 79.5% 为男性,年龄中位数为 41 岁。受试者有多种并发症,70.5%感染了丙型肝炎病毒。部分病例存在多种营养障碍:43.5%的患者有淋巴水肿,87%的患者有溃疡,56.5%的患者有注射相关疤痕。溃疡多发、面积大,中位数为 3 年。32.5%的病例溃疡位于上肢。64.5%的病例的溃疡是并发症的来源,91%的病例的并发症是感染性的(局部、骨关节或全身)。在随访期间,有8名患者死亡,21.5%需要溃疡护理的患者失去了随访机会:这项研究表明,注射毒品使用者的溃疡并发症发生率很高,尤其是感染。这些溃疡发生在上肢的情况虽然在普通人群中很少见,但在这一人群中却相对常见。随访工作十分困难,皮肤科医生和瘾君子科医生之间的合作对于改善患者护理至关重要。
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引用次数: 0
Health economic evaluation of topical treatments for external anogenital warts. 外生殖器疣局部治疗的卫生经济评估。
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-09-01 Epub Date: 2024-07-15 DOI: 10.1016/j.annder.2024.103288
H Agbeci, O Rollot, C Derancourt, Q Baglione, A Benard, A Bertolotti

Introduction: No treatment hierarchy for external anogenital warts (AGW) is currently recommended, despite wide variations in the costs of available treatments. The aim of this study was to propose a treatment hierarchy based on a health economic analysis of local treatments for AGW from the perspective of the French health insurance system.

Methods: Thirteen treatments and 73 treatment sequences were evaluated for AGW clearance and absence of AGW recurrence at 3 months of follow-up. The cost per treatment included the cost of consultations, drugs, medical procedures, and dressings. The time horizon was one year. The least expensive treatment was used as the reference treatment in the calculation of incremental cost-effectiveness ratios (ICERs). A two-line decision tree for treatment was constructed.

Results: Podophyllotoxin 0.5% solution was the least expensive treatment. Compared to podophyllotoxin 0.5% solution, the most cost-effective treatment was surgical excision (ICER: €456.82) and the most cost-effective treatment sequence was podophyllotoxin 0.5% solution followed by 5-fluorouracil (5-FU) 5% cream.

Conclusion: Considering the high risk of bias in the randomized controlled trials considered, the most cost-effective treatment sequence was podophyllotoxin 0.5% solution followed by 5-FU 5% cream.

导言:尽管现有的外生殖器疣(AGW)治疗方法成本差异很大,但目前并没有建议采用分级治疗方法。本研究的目的是从法国医疗保险体系的角度出发,根据对外生殖器疣局部治疗的卫生经济学分析,提出治疗分级:方法:对 13 种治疗方法和 73 个治疗序列进行了评估,以确定 AGW 是否清除,以及随访 3 个月后 AGW 是否复发。每次治疗的费用包括咨询费、药费、医疗程序费和敷料费。时间跨度为一年。在计算增量成本效益比(ICER)时,将成本最低的治疗方法作为参考治疗方法。构建了一个双线治疗决策树:结果:0.5%的鬼臼毒素溶液是成本最低的治疗方法。与荚叶素 0.5%溶液相比,最具成本效益的治疗方法是手术切除(ICER:456.82 欧元),最具成本效益的治疗顺序是荚叶素 0.5%溶液,然后是 5-氟尿嘧啶(5-FU)5% 乳膏:考虑到随机对照试验的高偏倚风险,最具成本效益的治疗顺序是先用0.5%的荚叶托品溶液,再用5%的5-氟尿嘧啶(5-FU)乳膏。
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引用次数: 0
Pemigatinib-associated calcinosis cutis: First case of complete regression with continued phosphate chelator therapy 佩吉加替尼相关性皮肤钙化症:持续磷酸盐螯合剂治疗后完全缓解的首例病例
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-27 DOI: 10.1016/j.annder.2024.103304
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引用次数: 0
Severe cholinergic urticaria: Clinical characteristics and therapeutic approach 严重胆碱能性荨麻疹:临床特征和治疗方法
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-27 DOI: 10.1016/j.annder.2024.103310
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引用次数: 0
Treatment of facial and axillary lupus miliaris with adalimumab 用阿达木单抗治疗面部和腋窝红斑狼疮
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-23 DOI: 10.1016/j.annder.2024.103307
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引用次数: 0
Nailfold capillaroscopy in acrocyanosis among patients with associated Raynaud’s phenomenon 伴有雷诺现象患者的甲沟炎毛细血管镜检查
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-22 DOI: 10.1016/j.annder.2024.103309
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引用次数: 0
Comedo-like Lesions on a verrucous epidermal nevus 疣状表皮痣上的 Comedo-like 病变。
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-19 DOI: 10.1016/j.annder.2024.103285
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引用次数: 0
Cutaneous infection with cowpox virus in the setting of a natural disaster 自然灾害背景下的牛痘病毒皮肤感染。
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-19 DOI: 10.1016/j.annder.2024.103306
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引用次数: 0
Squamous cell carcinoma on vitiligo in a dark-skinned patient 一名深肤色患者白癜风上的鳞状细胞癌。
IF 3.1 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-08-19 DOI: 10.1016/j.annder.2024.103308
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引用次数: 0
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Annales De Dermatologie Et De Venereologie
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