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Successful treatment of resistant lichen planopilaris with topical tofacitinib monotherapy 局部使用托法替尼单药成功治疗耐药性扁平苔藓
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-08-17 DOI: 10.1016/j.annder.2024.103303
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引用次数: 0
A retrospective and comparative analysis of suspected and confirmed Monkeypox virus-infected patients 对疑似和确诊猴痘病毒感染者的回顾性对比分析。
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-08-16 DOI: 10.1016/j.annder.2024.103302
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引用次数: 0
Mucocutaneous manifestations of inflammatory bowel disease 炎症性肠病的皮肤黏膜表现。
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-08-01 DOI: 10.1016/j.annder.2024.103301

Mucocutaneous manifestations can be indicative of a variety of gastrointestinal diseases, and the dermatologist needs to know how to recognize them to refer the right patients to the gastroenterologist. Conversely, the gastroenterologist is often confronted with mucocutaneous lesions that raise the question of a possible association with a known digestive disease.

Among the extra-intestinal manifestations of inflammatory bowel disease (IBD), mucocutaneous manifestations are the most common. This review will provide a breakdown by classifying them into 4 groups: 1) reactive manifestations, which include neutrophilic dermatoses, aphthous stomatitis, erythema nodosum, and vasculitis; 2) Crohn’s disease-specific granulomatous skin lesions, which are histologically characterized by tuberculoid granulomas similar to those found in the gastrointestinal tract; 3) nutritional deficiency manifestations secondary to anorexia, malabsorption, loss, and drug interactions; and 3) a variety of autonomous autoimmune or inflammatory skin diseases. Dermatologists may also be involved in the management of the adverse effects of IBD treatments, especially the so-called “paradoxical” psoriatic eruptions.

皮肤粘膜表现可能是多种胃肠道疾病的征兆，皮肤科医生需要知道如何识别这些表现，以便将合适的病人转诊给胃肠病医生。反之，胃肠病学家也经常会遇到皮肤粘膜病变，而这些病变可能与已知的消化系统疾病有关。在炎症性肠病（IBD）的肠道外表现中，粘膜表现最为常见。本综述将把它们分为四类：1）反应性表现，包括嗜中性粒细胞性皮肤病、阿弗他口腔炎、结节性红斑和血管炎；2）克罗恩病特异性肉芽肿性皮肤病变，其组织学特征为结核性肉芽肿，类似于胃肠道中发现的肉芽肿；3）继发于厌食、吸收不良、丢失和药物相互作用的营养缺乏表现；以及 3）各种自身免疫性或炎症性皮肤病。皮肤科医生还可能参与处理 IBD 治疗的不良反应，尤其是所谓的 "矛盾性 "银屑病爆发。
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引用次数: 0
Erosive toe-web intertrigo: Clinical features and management 侵蚀性趾网状支气管炎：临床特征和处理方法。
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-24 DOI: 10.1016/j.annder.2024.103263

Background

Toe-web (TW) intertrigo is a common disease of fungal or bacterial origin. Gram-negative bacterial (GNB) TW intertrigo consists of weeping, erosive, painful lesions that may be recurrent, leading to functional disability. Eczema is often associated with this condition. The management of intertrigo is poorly codified.

Objective

To evaluate the efficacy and safety of a standardized treatment plan using topical steroids in relation to the course and the frequency of recurrence of GNB-TW intertrigo.

Methods

We conducted a prospective open interventional multicentre study from June 2020 to June 2021. Standardised treatment using TCS together with follow-up via phone calls were performed over a 6-month period. In addition, a retrospective historical monocentric study was performed for patients with suspected TW-GNB intertrigo treated without standardized management.

The primary endpoint was disease duration. We performed a Wilcoxon test to compare the median duration of GNB-TW intertrigo in both series.

Results

We included 13 patients in the prospective cohort and 14 in the retrospective cohort.

In both cohorts, most patients were male with a median age of 59 years. The most frequent signs were fissures and exudates. Eczema was often associated (51.8%). Identified risk factors were psoriasis, local humidity, fungal intertrigo, vascular disease (arterial or venous insufficiency), and a history of multiple local treatments prior to diagnosis. Pseudomonas aeruginosa was the predominant pathogen (48.1%). Median durations of TW-GNB intertrigo were 56 days and 61 days. There was no significant difference in the median duration of the disease between the prospective and the retrospective cohorts (respectively 61 days and 56 days; p > 0.58). Relapses were more frequent in the retrospective cohort (respectively 7.7% and 21.4%).

Conclusion

GNB-TW intertrigo is a difficult-to-treat disease often associated with eczema. While topical corticosteroids (TCS) seem to be an effective and well-tolerated treatment they do not appear to reduce disease duration compared to other treatments.

背景：趾网（TW）性间皮瘤是一种常见的真菌或细菌性疾病。革兰氏阴性菌（GNB）引起的趾间皮炎包括流泪、糜烂、疼痛的皮损，可能反复发作，导致功能障碍。湿疹通常与此病有关。对唇间沟的治疗缺乏规范：评估使用局部类固醇激素的标准化治疗方案对 GNB-TW 三联征病程和复发频率的有效性和安全性：我们在 2020 年 6 月至 2021 年 6 月期间开展了一项前瞻性开放介入多中心研究。在 6 个月的时间里，我们使用 TCS 进行标准化治疗，并通过电话进行随访。此外，还对未接受标准化治疗的疑似 TW-GNB 室间隔患者进行了回顾性历史单中心研究。主要终点是病程。我们用 Wilcoxon 检验比较了两个系列中 GNB-TW 三联征的中位持续时间：结果：我们在前瞻性队列中纳入了 13 名患者，在回顾性队列中纳入了 14 名患者。两组患者均为男性，中位年龄均为 59 岁。最常见的体征是肛裂和渗出。湿疹也是常见症状（51.8%）。已确定的危险因素包括银屑病、局部潮湿、真菌性溃疡、血管疾病（动脉或静脉功能不全）以及确诊前多次局部治疗史。铜绿假单胞菌是主要病原体（48.1%）。TW-GNB 间皮瘤的中位持续时间分别为 56 天和 61 天。前瞻性研究组和回顾性研究组的中位病程无明显差异（分别为61天和56天；P > 0.58）。回顾性队列的复发率更高（分别为 7.7% 和 21.4%）：结论：GNB-TW 三联症是一种难以治疗的疾病，通常与湿疹有关。虽然外用皮质类固醇激素（TCS）似乎是一种有效且耐受性良好的治疗方法，但与其他治疗方法相比，它似乎并不能缩短病程。
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引用次数: 0
Primary cutaneous marginal zone B-cell lymphoma in an old tattoo 旧纹身上的原发性皮肤边缘区 B 细胞淋巴瘤。
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-24 DOI: 10.1016/j.annder.2024.103293
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引用次数: 0
Genitogluteal porokeratosis with dystrophic calcinosis on the scrotum 生殖器黄斑角化病伴有阴囊萎缩性钙化。
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-24 DOI: 10.1016/j.annder.2024.103252
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引用次数: 0
Extra-intestinal manifestation of Crohn’s disease: Umbilical lesion successfully treated with intralesional corticosteroids 克罗恩病的肠外表现：用皮质类固醇成功治疗脐部病变
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-22 DOI: 10.1016/j.annder.2024.103299
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引用次数: 0
Role of the primary care physician in skin cancer screening: Perspectives of skin cancer patients 主治医生在皮肤癌筛查中的作用：皮肤癌患者的观点
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-18 DOI: 10.1016/j.annder.2024.103298
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引用次数: 0
Vitiligo treated with oral baricitinib and heliotherapy: A case series 用口服巴利替尼和日光浴疗法治疗白癜风：病例系列
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-17 DOI: 10.1016/j.annder.2024.103300
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引用次数: 0
Id reaction during pediculosis capitis (Pediculid) 足癣（Pediculid）期间的 Id 反应
IF 3.1 4区 医学 Q2 DERMATOLOGY
Annales De Dermatologie Et De Venereologie
Pub Date : 2024-07-16 DOI: 10.1016/j.annder.2024.103297
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引用次数: 0
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