Annales De Dermatologie Et De Venereologie最新文献

英文中文

Unilesional folliculotropic mycosis fungoides associated with follicular mucinosis in children: 2 cases and literature review 儿童单发嗜滤泡性蕈样真菌病伴滤泡性黏液病2例并文献复习

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-12-01 DOI: 10.1016/j.annder.2024.103321

C. Pollyn-Millot , J.-F. Quinchon , P. Modiano , A. Lasek-Duriez

引用次数: 0

Two cases of bullous haemorrhagic dermatosis (BHD) induced by enoxaparin 依诺肝素致大疱性出血性皮肤病2例。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-12-01 DOI: 10.1016/j.annder.2024.103335

C. Wollenschlaeger, B. Cribier

引用次数: 0

Ocular and palpebral manifestations of mastocytosis: A prospective single-center study 肥大细胞增多症的眼部和眼睑表现：一项前瞻性单中心研究

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-28 DOI: 10.1016/j.annder.2024.103328

C. Guerin , E. Frouin , S. Doan , S. Charreau , C. Alleyrat , G. Tardieu , R. Flausse , M. Masson Regnault

Background

Ocular discomfort has been described as a frequent symptom in patients with mastocytosis, a rare disease resulting from accumulation of mast cells in organs.

Objectives

This study aims to assess the frequency and describe the nature of ocular and palpebral abnormalities in mastocytosis patients.

Patients and methods

We conducted a prospective, single-center study in adult mastocytosis patients, who were systematically examined by a dermatologist and an ophthalmologist with determination of tear cytokine levels.

Results

Twenty-one patients with a mean age of 60.7 ± 16.4 years were included. Nine patients presented with isolated cutaneous mastocytosis and 12 with indolent systemic mastocytosis. Seventeen patients (81.0%) presented with one or more eye symptoms. The most frequently reported symptoms were ocular itching (n = 12), dryness (n = 12), and excessive tearing (n = 9). Based on their Ocular Surface Disease Index scores, 11 patients (52.4%) were classified as having moderate or severe ocular surface disease. Eye examination revealed dry eye disease in 11 patients (52.4%), associated with superficial punctate keratitis in two patients and posterior blepharitis in 10 patients (47.6%). Tear cytokine levels of interleukin (IL)-1RA and IL-6 were not significantly different in mastocytosis patients compared to controls and did not vary according to ocular symptoms.

Conclusion

Dry eye disease and blepharitis were frequently found in this cohort of mastocytosis patients. Ocular consultation may be considered in this population to initiate eye hydration measures.

背景：肥大细胞增多症是一种由肥大细胞在器官内积聚引起的罕见疾病，其患者经常出现眼部不适。目的本研究旨在评估肥大细胞增多症患者眼部和眼睑异常的频率和性质。患者和方法我们对成年肥大细胞增多症患者进行了一项前瞻性、单中心研究，由皮肤科医生和眼科医生对患者进行系统检查，测定泪液细胞因子水平。结果21例患者平均年龄为60.7 ± 16.4 岁。9例患者表现为孤立性皮肤肥大细胞增多症，12例为无痛性全身肥大细胞增多症。17例患者（81.0%）出现一种或多种眼部症状。最常见的报告症状是眼痒（n = 12）、干燥（n = 12）和过度流泪（n = 9）。根据眼表疾病指数评分，11例（52.4%）患者分为中度或重度眼表疾病。眼部检查发现干眼病11例（52.4%），伴有浅表性点状角膜炎2例，后睑炎10例（47.6%）。肥大细胞增多症患者的泪液细胞因子白细胞介素(IL)-1RA和IL-6水平与对照组相比无显著差异，且不随眼部症状而变化。结论本组肥大细胞增多症患者常发生干眼病和眼睑炎。在这一人群中，可以考虑进行眼科咨询，以启动眼部补水措施。

{"title":"Ocular and palpebral manifestations of mastocytosis: A prospective single-center study","authors":"C. Guerin , E. Frouin , S. Doan , S. Charreau , C. Alleyrat , G. Tardieu , R. Flausse , M. Masson Regnault","doi":"10.1016/j.annder.2024.103328","DOIUrl":"10.1016/j.annder.2024.103328","url":null,"abstract":"<div><h3>Background</h3><div>Ocular discomfort has been described as a frequent symptom in patients with mastocytosis, a rare disease resulting from accumulation of mast cells in organs.</div></div><div><h3>Objectives</h3><div>This study aims to assess the frequency and describe the nature of ocular and palpebral abnormalities in mastocytosis patients.</div></div><div><h3>Patients and methods</h3><div>We conducted a prospective, single-center study in adult mastocytosis patients, who were systematically examined by a dermatologist and an ophthalmologist with determination of tear cytokine levels.</div></div><div><h3>Results</h3><div>Twenty-one patients with a mean age of 60.7 ± 16.4 years were included. Nine patients presented with isolated cutaneous mastocytosis and 12 with indolent systemic mastocytosis. Seventeen patients (81.0%) presented with one or more eye symptoms. The most frequently reported symptoms were ocular itching (<em>n</em> = 12), dryness (<em>n</em> = 12), and excessive tearing (<em>n</em> = 9). Based on their Ocular Surface Disease Index scores, 11 patients (52.4%) were classified as having moderate orsevere ocular surface disease. Eye examination revealed dry eye disease in 11 patients (52.4%), associated with superficial punctate keratitis in two patients and posterior blepharitis in 10 patients (47.6%). Tear cytokine levels of interleukin (IL)-1RA and IL-6 were not significantly different in mastocytosis patients compared to controls and did not vary according to ocular symptoms.</div></div><div><h3>Conclusion</h3><div>Dry eye disease and blepharitis were frequently found in this cohort of mastocytosis patients. Ocular consultation may be considered in this population to initiate eye hydration measures.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 1","pages":"Article 103328"},"PeriodicalIF":3.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142744635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leishmaniasis recidivans may be due to Leishmania tropica or Leishmania infantum 复发性利什曼病可能由热带利什曼病或婴儿利什曼病引起

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-25 DOI: 10.1016/j.annder.2024.103316

S. Chiheb, H. Jabri, I. El Idrissi Saik, A. Kihel, M. Lemrani, K. Akarid, M. Soussi Abdallaoui, M. Riyad

引用次数: 0

Lupus miliaris disseminatus with axillary localisation treated with isotretinoin 用异维A酸治疗腋窝局部的播散性红斑狼疮。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-22 DOI: 10.1016/j.annder.2024.103311

T. Pigné, P. Schmoor, S. Menguy, M.-S. Doutre

引用次数: 0

Clinical relevance and prognostic impact of the classification between multibacillary and paucibacillary forms of cutaneous tuberculosis: A 24-year retrospective multicenter study 多脓疱型和少脓疱型皮肤结核分类的临床意义和预后影响：一项为期 24 年的多中心回顾性研究。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-22 DOI: 10.1016/j.annder.2024.103324

V. Bérot , G. Monsel , E. Lecorche , M. Halabi-Tawil , D. Maalouf , V. Pourcher , A. Aubry , E. Cambaud , A. Petit , E. Caumes

Objectives

Cutaneous tuberculosis (CTB) may be over-diagnosed due to imprecise diagnostic criteria or overlooked where mycobacterial investigations are negative. We evaluated the distinction between multibacillary and paucibacillary forms of CTB, as well as drug resistance and cure rates according to the results of mycobacterial investigations.

Methods

We included retrospectively all patients diagnosed with CTB from 1995 to 2018 in two hospitals in Paris. Clinical forms were classified according to dermatological descriptions, into multibacillary (e.g. gumma, scrofuloderma, orificial TB) and paucibacillary forms (lupus vulgaris, verrucous tuberculosis, papulonecrotic tuberculids, nodular panniculitis). A distinction was made between microbiologically confirmed CTB and presumed CTB forms, which were treated presumptively. Cure was defined as the complete resolution of CTB in patients who completed anti-tuberculosis treatment.

Results

Among the 124 patients with CTB, the most common forms were nodular panniculitis (30.6%), scrofuloderma (22.6%), gumma (18.6%), and lupus vulgaris (12.1%). Tuberculosis was confirmed in 78 patients (62.9%), among whom 13 (16.7%) exhibited resistance to anti-tuberculous drugs, and 46 were presumptively treated. Mycobacterial investigations were significantly more frequently positive for multibacillary (88.2%) than for paucibacillary CTB (39.3%) (p < 10⁻⁶). Patients with mycobacterial evidence of CTB exhibited significantly better cure rates than patients without (96.7% vs. 66.7%, p < 10⁻⁴), particularly among those with nodular panniculitis (100% vs. 63.0%, p < 10⁻³).

Conclusion

The distinction between paucibacillary and multibacillary CTB is relevant. Resistant strains may be isolated. Antituberculosis drugs should be prescribed with caution in cases of panniculitis in the absence of evidence of mycobacterial infection.

目的：皮肤结核（CTB）可能因诊断标准不精确而被过度诊断，或在分枝杆菌检查阴性时被忽视。我们根据分枝杆菌检查的结果，评估了多脓疱型和贫脓疱型 CTB 的区别，以及耐药性和治愈率：我们回顾性地纳入了1995年至2018年在巴黎两家医院确诊的所有CTB患者。根据皮肤病学描述，将临床形式分为多疱疹型（如牙龈瘤、瘰疬性皮肤病、人工肺结核）和贫疱疹型（寻常狼疮、疣状肺结核、丘疹性肺结核、结节性泛发性肺结核）。经微生物学确诊的 CTB 与推测的 CTB 形式有所区别，前者属于推测性治疗。治愈的定义是完成抗结核治疗的患者 CTB 完全消退：结果：在 124 名 CTB 患者中，最常见的 CTB 类型为结节性泛发性皮肤炎（30.6%）、瘰疬性皮肤病（22.6%）、牙龈肿痛（18.6%）和寻常狼疮（12.1%）。78 名患者（62.9%）确诊为肺结核，其中 13 人（16.7%）对抗结核药物有抗药性，46 人接受了推定治疗。在分枝杆菌检查中，多枝杆菌阳性率（88.2%）明显高于普通型 CTB 阳性率（39.3%）（P-6）。有分枝杆菌证据的 CTB 患者的治愈率明显高于无分枝杆菌证据的患者（96.7% 对 66.7%，P-4），尤其是结节性泛发性 CTB 患者（100% 对 63.0%，P-3）：结论：区分贫乳头状瘤和多乳头状瘤 CTB 是有意义的。可能会分离出耐药菌株。在没有分枝杆菌感染证据的情况下，应慎用抗结核药物。

{"title":"Clinical relevance and prognostic impact of the classification between multibacillary and paucibacillary forms of cutaneous tuberculosis: A 24-year retrospective multicenter study","authors":"V. Bérot , G. Monsel , E. Lecorche , M. Halabi-Tawil , D. Maalouf , V. Pourcher , A. Aubry , E. Cambaud , A. Petit , E. Caumes","doi":"10.1016/j.annder.2024.103324","DOIUrl":"10.1016/j.annder.2024.103324","url":null,"abstract":"<div><h3>Objectives</h3><div>Cutaneous tuberculosis (CTB) may be over-diagnosed due to imprecise diagnostic criteria or overlooked where mycobacterial investigations are negative. We evaluated the distinction between multibacillary and paucibacillary forms of CTB, as well as drug resistance and cure rates according to the results of mycobacterial investigations.</div></div><div><h3>Methods</h3><div>We included retrospectively all patients diagnosed with CTB from 1995 to 2018 in two hospitals in Paris. Clinical forms were classified according to dermatological descriptions, into multibacillary (e.g. gumma, scrofuloderma, orificial TB) and paucibacillary forms (lupus vulgaris, verrucous tuberculosis, papulonecrotic tuberculids, nodular panniculitis). A distinction was made between microbiologically confirmed CTB and presumed CTB forms, which were treated presumptively. Cure was defined as the complete resolution of CTB in patients who completed anti-tuberculosis treatment.</div></div><div><h3>Results</h3><div>Among the 124 patients with CTB, the most common forms were nodular panniculitis (30.6%), scrofuloderma (22.6%), gumma (18.6%), and lupus vulgaris (12.1%). Tuberculosis was confirmed in 78 patients (62.9%), among whom 13 (16.7%) exhibited resistance to anti-tuberculous drugs, and 46 were presumptively treated. Mycobacterial investigations were significantly more frequently positive for multibacillary (88.2%) than for paucibacillary CTB (39.3%) (p < 10<sup>−6</sup>). Patients with mycobacterial evidence of CTB exhibited significantly better cure rates than patients without (96.7% vs. 66.7%, p < 10<sup>−4</sup>), particularly among those with nodular panniculitis (100% vs. 63.0%, p < 10<sup>−3</sup>).</div></div><div><h3>Conclusion</h3><div>The distinction between paucibacillary and multibacillary CTB is relevant. Resistant strains may be isolated. Antituberculosis drugs should be prescribed with caution in cases of panniculitis in the absence of evidence of mycobacterial infection.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 4","pages":"Article 103324"},"PeriodicalIF":3.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric oxygen therapy enables pain reduction and healing in painful chronic wounds, including in calciphylaxis 高压氧疗法可减轻慢性疼痛性伤口（包括钙化性伤口）的疼痛并促进其愈合。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-22 DOI: 10.1016/j.annder.2024.103325

E. Pathault , S. Sanchez , B. Husson , C. Vanhaecke , P. Georges , C. Brazier , B. Mourvillier , M. Viguier

Background

The effects of hyperbaric oxygen therapy (HBOT) on wound healing have been demonstrated mainly in diabetic foot ulcer.

Objectives

To study the efficacy and safety of HBOT in chronic painful wounds, excluding diabetic foot ulcers.

Methods

From 2008 to 2021, patients with chronic wounds showing no clinical improvement for more than 1 month, who were in pain despite the use of level 2 or 3 analgesics, and who had undergone HBOT sessions, were included in a monocentric retrospective study. The primary objective was to evaluate the course of pain by studying analgesic consumption before and up to a maximum of 12 months after HBOT. Achievement of complete or partial healing was also recorded.

Results

Eighteen patients with calciphylaxis (n = 6), vasculitis (n = 4), hypertensive leg ulcer (n = 3), mixed ulcer (n = 3), Buerger’s disease (n = 1), and livedoid vasculitis (n = 1) were included.

Decrease in analgesic step, dose or number was noted in 15 of 18 patients (83.3%) within a median time of 3.5 (0.3–12) months, with a significant decrease in strong opioid use (72.2% before vs. 11.1% after, p = 0.005), as well as local improvement in 15 of 18 patients (83.3%) within a median time of 3.9 (1–10.3) months.

Conclusion

HBOT as an adjuvant in chronic painful wounds of various etiologies allows a significant reduction in strong opioid consumption. This finding in a population with frequent adverse reactions to opioids requires demonstration in prospective and controlled studies.

背景：高压氧疗法（HBOT）对伤口愈合的影响主要在糖尿病足溃疡中得到证实：研究高压氧治疗对慢性疼痛伤口（不包括糖尿病足溃疡）的疗效和安全性：方法：2008 年至 2021 年期间，一项单中心回顾性研究纳入了临床症状改善不超过 1 个月、使用 2 级或 3 级止痛药后仍有疼痛感、接受过 HBOT 治疗的慢性伤口患者。研究的主要目的是通过研究 HBOT 前和 HBOT 后最长 12 个月的镇痛剂消耗情况，评估疼痛的过程。研究还记录了完全或部分痊愈的情况：结果：共纳入了 18 名患有钙化性溃疡（6 人）、脉管炎（4 人）、高血压性腿部溃疡（3 人）、混合性溃疡（3 人）、Buerger 病（1 人）和活体脉管炎（1 人）的患者。18名患者中有15名（83.3%）在3.5（0.3-12）个月的中位时间内减少了镇痛步骤、剂量或次数，强阿片类药物的使用显著减少（治疗前72.2%，治疗后11.1%，P = 0.005），18名患者中有15名（83.3%）在3.9（1-10.3）个月的中位时间内局部症状有所改善：结论：将 HBOT 作为各种病因引起的慢性疼痛伤口的辅助治疗可显著减少阿片类药物的用量。这一发现适用于阿片类药物不良反应频繁的人群，需要在前瞻性对照研究中加以证实。

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引用次数: 0

Pinkus fibroepithelioma of the scrotum: An unusual location in a young patient 阴囊粉红纤维上皮瘤：一名年轻患者的不寻常部位。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-06 DOI: 10.1016/j.annder.2024.103326

D.-M. Loga , R. Salle , I. Moulonguet , T.-A. Duong , J.-N. Dauendorffer

引用次数: 0

Azacitidine-related pyoderma gangrenosum 阿扎胞苷相关脓皮病。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-11-01 DOI: 10.1016/j.annder.2024.103323

S. Maral, E. Uzunabdullah, N. Zilan Yamis, E. Kuzucular, B. Surul, O. Gokmen Sevindik

引用次数: 0

Promoting the use of simulation in therapeutic patient education 在病人治疗教育中推广使用模拟教学。

IF 3.1 4区医学 Q2 DERMATOLOGY

Annales De Dermatologie Et De Venereologie

Pub Date : 2024-10-22 DOI: 10.1016/j.annder.2024.103322

J. Prémel, C. Authier, H. Humeau, E.-P. Libert, S. Dubois, L. Martin

引用次数: 0

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