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Annales De Dermatologie Et De Venereologie最新文献

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Concurrent red scrotum and red ear syndromes: successful resolution with amitriptyline 并发红阴囊和红耳综合征:阿米替林成功解决
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-10-10 DOI: 10.1016/j.annder.2025.103373
C. Skayem, R. Salle, S. Fouere, J.-D. Bouaziz, T.-A. Duong, J.-N. Dauendorffer
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引用次数: 0
Erythrosis pigmentosa mediofacialis (Brocq): A hypothesis on the involvement of Demodex folliculorum 中面部色素性红肿:关于毛囊蠕形螨累及的一种假说
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-19 DOI: 10.1016/j.annder.2025.103412
M. Piroth, A. Lopes, M. Vourc’h, E. Guigne, J.-M. Chavigny, S. Lachaise, C. Lenormand, B. Cribier, S. Barbarot, M. Viguier
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引用次数: 0
Skin-adverse drug reactions in the elderly: An underestimated and avoidable issue 老年人皮肤药物不良反应:一个被低估和可避免的问题
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-11-08 DOI: 10.1016/j.annder.2025.103445
M. Lagassy , A. Lefebvre , P. Carvalho , P. Joly , F. Roca , T. Pressat Laffouilhere , J. Grosjean , F. Tetart

Background

Ageing is a major public health concern. It is often associated with frailty and polymedication, which can lead to adverse drug reactions (ADRs), including skin-related ADRs.

Objective

To describe skin-ADRs in elderly people admitted to a dermatology ward, identify causative drugs, and investigate whether these skin-ADRs were avoidable.

Methods

We conducted a single-centre, retrospective study and recruited patients aged over 70 years admitted for skin-ADRs. Included reactions consisted of maculopapular exanthema (MPE), symmetrical drug-related intertriginous flexural exanthema, fixed drug eruption, acute generalised exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS), and toxic epidermal necrolysis/Stevens-Johnson syndrome. Variables: demographics, drug hypersensitivity history, skin-ADR characteristics, causative drugs, avoidability, therapeutic outcomes, and one-year follow-up.

Results

Between 2010 and 2020, 80 patients (57 women, mean age 82) were included. 32 % had a history of drug hypersensitivity; 64 % were polymedicated. Skin-ADRs were non-severe in 65 % (60 % MPE) and severe in 35 % (23 % DRESS, 9 % AGEP). Causative drugs were antibiotics (85 %), cardiovascular (16 %), and anticancer agents (9 %). 21 % of skin-ADRs were avoidable. 15 % developed new skin-ADRs after unintentional rechallenge during follow-up.

Conclusion

Greater clinical awareness of drug hypersensitivity history could improve elderly care and reduce dermatology ward hospitalisations.
老龄化是一个重大的公共卫生问题。它通常与虚弱和多种药物有关,这可能导致药物不良反应(adr),包括与皮肤有关的adr。目的了解皮肤科住院老年人皮肤不良反应的发生情况,确定引起皮肤不良反应的药物,并探讨这些皮肤不良反应是否可以避免。方法采用单中心回顾性研究,招募年龄在70岁以上 岁以上因皮肤不良反应入院的患者。包括斑疹丘疹(MPE)、对称性药物相关性三节间曲疹、固定药疹、急性全身性脓疱病(AGEP)、嗜酸性粒细胞增多和全身症状的药物反应(DRESS)、中毒性表皮坏死松解/Stevens-Johnson综合征。变量:人口统计学、药物超敏史、皮肤不良反应特征、致病药物、可避免性、治疗结果、1年随访。结果2010 - 2020年共纳入80例患者(女性57例,平均年龄82岁)。32 %有药物过敏史;64 %多药。65 %(60 % MPE)皮肤不良反应不严重,35 %(23 % DRESS, 9 % AGEP)皮肤不良反应严重。致病性药物为抗生素(85 %)、心血管药物(16 %)和抗癌药物(9 %)。21% %的皮肤不良反应是可以避免的。15 %在随访期间意外再挑战后发生新的皮肤不良反应。结论提高临床对药物过敏史的认识,可改善老年护理,减少皮肤科住院。
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引用次数: 0
Unilateral localized hyperhidrosis: Eccrine nevus 单侧局部多汗症:汗腺痣
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-09-09 DOI: 10.1016/j.annder.2025.103423
M. Carmi , I. Lafhaj , F. Plantier , E. Carmi
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引用次数: 0
Muir-Torre syndrome revealed by sebaceous carcinoma of the scrotum 阴囊皮脂腺癌显示的Muir-Torre综合征
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-19 DOI: 10.1016/j.annder.2025.103402
D.-M. Loga , R. Salle , B. Cavelier-Balloy , C. Lacoste , S. Fouéré , C. Lebbé , J.-D. Bouaziz , T.-A. Duong , J.-N. Dauendorffer
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引用次数: 0
Eyelash phthiriasis: therapeutic success with oral ivermectin 睫毛癣:口服伊维菌素治疗成功
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-19 DOI: 10.1016/j.annder.2025.103405
N. Chebbawi, F. Elfatoiki, F. Hali, S. Chiheb
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引用次数: 0
Ripretinib-related pyoderma gangrenosum: first description and pathophysiological clues 利普雷替尼相关坏疽性脓皮病:首次描述和病理生理线索
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-08-19 DOI: 10.1016/j.annder.2025.103410
M. Valerio, T. Valentin, V. Sibaud
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引用次数: 0
Prevalence and characteristics of cold-induced cutaneous and vascular manifestations among runners 跑步者冷致皮肤和血管表现的患病率和特点
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-09-02 DOI: 10.1016/j.annder.2025.103426
N. Kluger , S. Leclerc-Mercier
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引用次数: 0
Dramatic efficacy of omalizumab in a case of severe delayed pressure urticaria in a teenager 奥玛珠单抗治疗青少年严重迟发性压性荨麻疹的显著疗效
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-09-13 DOI: 10.1016/j.annder.2025.103425
N. Kluger , K. Mikola
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引用次数: 0
Allergological work-up of severe cutaneous adverse reactions with suspicion of anxiolytics or sleeping pills. A multicenter retrospective study of 20 cases 严重皮肤不良反应的过敏检查,怀疑有抗焦虑药或安眠药。20例病例的多中心回顾性研究。
IF 2.8 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-01 Epub Date: 2025-11-24 DOI: 10.1016/j.annder.2025.103398
S. Ingen-Housz-Oro , F. Dezoteux , C. Bernier , E. Le Bidre , D. Staumont-Sallé , A. Welfringer-Morin , V. Beaulieu , M. Tauber , K. Bel Hareth , H. Assier
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引用次数: 0
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Annales De Dermatologie Et De Venereologie
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