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Use of spironolactone for the treatment of acne in adolescent girls 使用螺内酯治疗少女痤疮
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-05-22 DOI: 10.1016/j.annder.2024.103281
D. Canu, S. Mary-Prey, A. Legrand, C. Leauté-Labreze
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引用次数: 0
Barriers and suggestions for improving the implementation of guidelines in the systemic treatment of moderate to severe psoriasis: A literature review 改善中重度银屑病系统治疗指南实施的障碍和建议:文献综述
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-05-22 DOI: 10.1016/j.annder.2024.103280
V. Kalita, D. Abs, A.-C. Bursztejn

Background

Despite the availability of a wide range of therapies for the systemic treatment of moderate to severe psoriasis, many psoriasis patients do not receive adequate treatment, suggesting that guidelines may not be correctly applied by physicians.

Objectives

The aim of this study was to analyze data on physicians’ implementation of, and reasons for noncompliance with, guidelines for the systemic treatment of moderate to severe psoriasis.

Methods

We conducted a systematic literature review according to the Preferred Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the PubMed and Embase databases for studies on guideline adherence in the systemic treatment of moderate to severe psoriasis. All eligible articles were retrieved in full text and the relevant references of retrieved articles were included.

Results

A total of 20 studies were selected. Four studies investigated knowledge of the guidelines, six studies examined their application, and five studies focused on the various barriers to implementation. Finally, five studies discussed ways to improve implementation. Several studies on the quality of psoriasis care have revealed discrepancies between the reality and the optimal care described in national and international guidelines.

Conclusion

Various barriers to implementation of recommendations exist, such as economic barriers, lack of dermatologic orientation towards, lack of knowledge of recommendations by other specialists, lack of applicability, and country- and practice-specific features (e.g., different benefit/risk ratios, different reimbursement rates and conditions). This review can help the everyday practitioner to better understand these barriers, which will have a direct impact on improving the quality of life of psoriasis patients.

背景尽管目前有多种疗法可用于中重度银屑病的系统治疗,但许多银屑病患者并未得到适当的治疗,这表明医生可能并未正确应用指南。我们在 PubMed 和 Embase 数据库中检索了有关中度至重度银屑病系统治疗指南依从性的研究。我们检索了所有符合条件的文章全文,并纳入了检索文章的相关参考文献。四项研究调查了对指南的了解情况,六项研究考察了指南的应用情况,五项研究关注了指南实施过程中遇到的各种障碍。最后,五项研究讨论了改进实施的方法。几项关于银屑病治疗质量的研究显示,现实情况与国家和国际指南中描述的最佳治疗之间存在差异。结论建议的实施存在各种障碍,如经济障碍、缺乏皮肤病学方向、其他专家对建议缺乏了解、缺乏适用性以及国家和实践的特殊性(如不同的收益/风险比、不同的报销比例和条件)。本综述有助于日常从业人员更好地了解这些障碍,这将对改善银屑病患者的生活质量产生直接影响。
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引用次数: 0
Abundant CD30+ lymphocyte infiltrate in idiopathic perniosis 特发性羊膜炎中大量 CD30+ 淋巴细胞浸润
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-05-22 DOI: 10.1016/j.annder.2024.103279
D. Canu, F. Beltzung, P. Poizac, M.-S. Doutre
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引用次数: 0
Promoting clinical research in community-based practice: Threats and opportunities 促进社区实践中的临床研究:威胁与机遇
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-29 DOI: 10.1016/j.annder.2024.103272
F. Poizeau , A. Maruani , D. Staumont-Sallé , N. Jouan , S. Ly , M. Schollhammer , M. Reverte , C. Dibao-Dina , T.-A. Duong , B. Matard , D. Penso-Assathiany , A. Dupuy , M. Carriot , J.-F. Seï , F. Corgibet , B. Guillot , S. Barbarot , S. Leducq , A. Bertolotti , J. Tannous , O. Chosidow
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引用次数: 0
PATEO syndrome PATEO 综合征
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103267
N. Lacroix, D. Anghel, V. Sibaud
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引用次数: 0
Pruriginous vesicular eruption associated with nivolumab immunotherapy: A case of dermatitis herpetiformis 与 nivolumab 免疫疗法相关的瘙痒性水泡疹:一例疱疹性皮炎病例
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103269
M. Housset, A. Fayad Kazour, C. Paugam, Y. Le Corre, A. Croue, L. Martin, D. Lechevalier, C. Berthin
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引用次数: 0
Vestibulodynia: Clinical characteristics, first-line treatments, and factors associated with escalation of treatment with EMG–guided injections of botulinum toxin in a retrospective french cohort study 眩晕症:一项回顾性法国队列研究中的临床特征、一线治疗方法以及与肌电图引导下注射肉毒杆菌毒素治疗升级相关的因素
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103277
C. Neuville , B. Parratte , S. Lombion , F. Aubin , I. Gallais Sérézal , F. Pelletier

Background

Vestibulodynia is a highly prevalent chronic pain disorder affecting the vulva having a major impact on women’s physical, psychological, and sexual well-being. It remains an underrecognized disease that responds insufficiently to therapies such as physiotherapy and medication.

Aim

To assess the global efficacy of first-line therapies and factors associated with treatment escalation in women with vestibulodynia.

Patients and methods

This retrospective cohort study was conducted at the dermatology outpatient clinic of the University Hospital in Besancon (France) between 2013 and 2017 and follow-up until 2021.

Results

Among 132 patients, the mean [standard deviation] age at diagnosis was 27.2 [±9.45] years, with an average duration of symptoms of 42.3 [±37.92] months. Most cases comprised provoked (75.0%) or secondary (72.7%) vestibulodynia. At least one comorbid pain or psychologic condition was identified respectively in 63 (47.7%) and 23 patients (54.5%). Vulvar hyperesthesia associated with pelvic floor muscle dysfunction was present in 121 patients (91.6%) and vulvar erethism was noted in 94 patients (71.2%). First-line treatments consisted of pelvic floor physiotherapy with biofeedback in 85% of patients, associated with amitriptyline in 36% of cases, and of additional lidocaine cream in 17%. Fifty-two patients (39%) presented at least a good response to first-line treatment, with only 21 (15%) being in complete remission, irrespective of therapeutic strategy (p = 0.25). Botulinum toxin injections were performed in 54 patients. Patients with either primary vestibulodynia (p = 0.04) or spontaneous vestibulodynia (p = 0.03) were more likely to receive this treatment.

Conclusion

Our study highlights the current lack of efficacy of first-line treatments in vestibulodynia. Considering the high prevalence of muscular dysfunction, botulinum toxin injections are of particular interest despite a lack of randomized controlled trials in this indication.

背景膀胱阴道炎是一种影响外阴的高发慢性疼痛疾病,对女性的生理、心理和性健康有重大影响。目的评估前庭大腺炎女性患者一线疗法的总体疗效以及与治疗升级相关的因素。结果132名患者中,平均[标准差]诊断年龄为27.2 [±9.45]岁,平均症状持续时间为42.3 [±37.92]个月。大多数病例为诱发性(75.0%)或继发性(72.7%)前庭大腺炎。63名患者(47.7%)和23名患者(54.5%)至少合并一种疼痛或心理疾病。121名患者(91.6%)出现与盆底肌肉功能障碍相关的外阴过度收缩,94名患者(71.2%)出现外阴糜烂。85%的患者接受了带生物反馈的盆底物理治疗,36%的患者接受了阿米替林治疗,17%的患者接受了额外的利多卡因乳膏治疗。52名患者(39%)对一线治疗至少有良好反应,只有21名患者(15%)完全缓解,与治疗策略无关(P = 0.25)。54名患者接受了肉毒杆菌毒素注射。原发性前庭神经痛(p = 0.04)或自发性前庭神经痛(p = 0.03)的患者更有可能接受这种治疗。考虑到肌肉功能障碍的高发病率,肉毒杆菌毒素注射尤其值得关注,尽管在这一适应症方面缺乏随机对照试验。
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引用次数: 0
Panitumumab-induced perforating collagenosis 帕尼单抗诱发的穿孔性胶原病
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103271
N. Kluger, S. Jokela, L. Tolkki
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引用次数: 0
Routine dermatology training and tele-expertise for general practitioners 为全科医生提供常规皮肤病学培训和远程专家培训
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103266
P. Senet
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引用次数: 0
Tele-expertise assessment of chronic wounds by advanced practice dermatology nurses 皮肤科高级护士对慢性伤口进行远程专家评估
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2024-04-27 DOI: 10.1016/j.annder.2024.103273
C. Robin , L. Poiroux , J. Delaunay , P. Seuwou , L. Martin , E. Démoulins
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引用次数: 0
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Annales De Dermatologie Et De Venereologie
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