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Extrinsic and intrinsic effects setting viscosity in complex fluids and life processes: the role of fundamental physical constants 复杂流体和生命过程中粘度的外在和内在影响:基本物理常数的作用
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2025-01-03 DOI: 10.1140/epje/s10189-024-00467-y
K. Trachenko, P. G. Tello, S. A. Kauffman, S. Succi

Understanding the values and origin of fundamental physical constants, one of the grandest challenges in modern science, has been discussed in particle physics, astronomy and cosmology. More recently, it was realized that fundamental constants have a biofriendly window set by life processes involving motion and flow. This window is related to intrinsic fluid properties such as energy and length scales in condensed matter set by fundamental constants. Here, we discuss important extrinsic factors governing the viscosity of complex fluids operating in life processes due to collective effects. We show that both extrinsic and intrinsic factors affecting viscosity need to be taken into account when estimating the biofriendly range of fundamental constants from life processes, and our discussion provides a straightforward recipe for doing this. Remarkably, the viscosity of a complex fluid such as blood with significant extrinsic effects is not far from the intrinsic viscosity calculated using the fundamental constants only, and we discuss the reason for this in terms of dynamics of contact points between cells.

理解基本物理常数的值和起源是现代科学中最大的挑战之一,在粒子物理学、天文学和宇宙学中都有讨论。最近,人们意识到,基本常数有一个生物友好的窗口,由涉及运动和流动的生命过程设置。这个窗口与固有的流体性质有关,如由基本常数设定的凝聚态物质的能量和长度尺度。在这里,我们讨论了在生命过程中由于集体效应而控制复杂流体粘度的重要外在因素。我们表明,在估计生命过程中基本常数的生物友好范围时,需要考虑影响粘度的外在因素和内在因素,我们的讨论为这样做提供了一个简单的方法。值得注意的是,具有显著外在效应的复杂流体(如血液)的粘度与仅使用基本常数计算的本征粘度相差不远,我们从细胞间接触点的动力学角度讨论了这一现象的原因。
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引用次数: 0
A hitchhiker’s guide to active motion 主动运动的搭便车指南
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2025-01-03 DOI: 10.1140/epje/s10189-024-00465-0
Tobias Plasczyk, Paul A. Monderkamp, Hartmut Löwen, René Wittmann

Intelligent decisions in response to external informative input can allow organisms to achieve their biological goals while spending very little of their own resources. In this paper, we develop and study a minimal model for a navigational task, performed by an otherwise completely motorless particle that possesses the ability of hitchhiking in a bath of active Brownian particles (ABPs). Hitchhiking refers to identifying and attaching to suitable surrounding bath particles. Using a reinforcement learning algorithm, such an agent, which we refer to as intelligent hitchhiking particle (IHP), is enabled to persistently navigate in the desired direction. This relatively simple IHP can also anticipate and react to characteristic motion patterns of their hosts, which we exemplify for a bath of chiral ABPs (cABPs). To demonstrate that the persistent motion of the IHP will outperform that of the bath particles in view of long-time ballistic motion, we calculate the mean-squared displacement and discuss its dependence on the density and persistence time of the bath ABPs by means of an analytic model.

Illustration of an intelligent hitchhiking particle (IHP) in a bath of active Brownian particles (ABPs). The IHP fulfills a navigational task by holding on to an ABP only if its orientation points upwards, enabling persistent motion.

响应外部信息输入的智能决策可以使生物体在花费很少的自身资源的情况下实现其生物目标。在本文中,我们开发和研究了一个导航任务的最小模型,该模型由一个完全无运动的粒子执行,该粒子具有搭便车活动布朗粒子(ABPs)浴的能力。搭便车是指识别并附着在周围合适的浴液颗粒上。使用强化学习算法,这样的代理,我们称之为智能搭便车粒子(IHP),能够持续地在期望的方向上导航。这种相对简单的IHP还可以预测并对宿主的特征运动模式做出反应,我们以手性ABPs (cABPs)为例。考虑到长时间的弹道运动,为了证明射流粒子的持续运动优于熔池粒子的持续运动,我们计算了均方位移,并通过解析模型讨论了其与熔池射流粒子密度和持续时间的关系。智能搭便车粒子(IHP)在活跃布朗粒子(ABPs)浴中的图示。只有当ABP的方向指向上方时,IHP才会抓住它来完成导航任务,从而实现持续运动。
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引用次数: 0
Bifurcation analysis and control of the full velocity difference model with delayed velocity difference 时滞速度差全速度差模型的分岔分析与控制
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-12-08 DOI: 10.1140/epje/s10189-024-00462-3
Wenhuan Ai, Guoao Li, Jianhua Zhang, Xiaoshuang Zhu, Dawei Liu

With the increase in the number of urban vehicles, various traffic problems have gradually emerged. Studying the causes of traffic congestion and proposing effective mitigation strategies have important practical significance. This paper proposes a macroscopic traffic flow model that considers the delayed speed difference. This paper applies nonlinear bifurcation to describe and predict nonlinear traffic phenomena on highways from the perspective of global stability of the traffic system. By using the traveling wave transformation, the proposed car-following model is converted into a macroscopic traffic flow model. Next, this paper employs the linear stability analysis to find the bifurcation points of the stability transition in the traffic system, exploring the qualitative characteristics of the inhomogeneous continuous traffic flow model. Theoretical derivations demonstrate the existence of bifurcation points within the model. Additionally, this paper plots the density-time space diagrams and phase plane diagrams of the system to visually present the sudden changes in traffic flow as variable parameters pass through these bifurcation points. Finally, this paper designs a feedback controller to regulate the Hopf bifurcation, aiming to delay or eliminate the occurrence of Hopf bifurcations in the stochastic system.

Graphical abstract

随着城市车辆数量的增加,各种交通问题逐渐显现。研究交通拥堵的成因并提出有效的缓解策略具有重要的现实意义。本文提出了一个考虑延迟速度差的宏观交通流模型。本文从交通系统全局稳定性的角度出发,运用非线性分岔理论来描述和预测公路上的非线性交通现象。通过行波变换,将所提出的车辆跟随模型转化为宏观交通流模型。其次,本文采用线性稳定性分析方法寻找交通系统稳定性过渡的分岔点,探讨非齐次连续交通流模型的定性特征。理论推导证明了模型中存在分岔点。并绘制了系统的密度-时间-空间图和相平面图,直观地呈现了变参数经过这些分岔点时交通流的突变。最后,本文设计了一个反馈控制器来调节Hopf分岔,目的是延迟或消除随机系统中Hopf分岔的发生。图形抽象
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引用次数: 0
Characterization of dynamic interplay among different channels during immiscible displacement in porous media under different flow rates 不同流量下多孔介质非混相驱替过程中不同通道间动态相互作用的表征
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-12-07 DOI: 10.1140/epje/s10189-024-00463-2
Yusong Xu, Yingxue Hu, Kaixin Chen, Yuanqing Liu, Jiangang Liu, Weiwei Hao, Tianjiang Wu, Chuanqing Huang, Junwei Su

Although immiscible displacement in porous media has been extensively studied, a more comprehensive analysis of the underlying dynamic behaviors is still necessary. In this work, we conducted experimental and theoretical analyses on the dynamic interplay among channels during immiscible displacement under varying flow rates. In a rock-structured microfluidic chip, we observed typical displacement patterns, including viscous fingering and capillary fingering, and analyzed their frontiers and efficiencies. Interestingly, we discovered a novel 'V'-shaped recovery rate pattern, which differs from the monotonic curve considered in previous research. The recovery rate reaches its lowest point at an injection rate of 1 μL/min (42%), increasing to 55 and 65% at rates of 16 and 0.1 μL/min, respectively. This increase may attribute to all-directional displacement at lower rates and multi-fingering displacement at higher rates, contrasting with primary fingering displacement observed at intermediate rates. Furthermore, we developed a dual-tube model to investigate the dynamic mechanisms between adjacent channels during the displacement process. At high injection rates, an increase in low-viscosity fluid rapidly reduces overall average viscosity of the channels, accelerating displacement while hindering the displacement process in neighboring channels. Conversely, at low injection rates, increased capillary forces at pore-throat junctions delay breakthrough in one channel, promoting simultaneous displacement in parallel channels and ensuring stability. These findings significantly enhance our understanding of the interplay between viscous and capillary forces in porous media during displacement processes.

Graphical abstract

尽管多孔介质中的非混相驱替已经得到了广泛的研究,但对其潜在的动力学行为进行更全面的分析仍然是必要的。在这项工作中,我们对不同流量下非混相驱替过程中通道间的动态相互作用进行了实验和理论分析。在岩石结构微流控芯片中,我们观察了典型的位移模式,包括粘性指移和毛细指移,并分析了它们的边界和效率。有趣的是,我们发现了一个新的“V”型回收率模式,不同于以往研究中考虑的单调曲线。在注射速度为1 μL/min时,回收率最低(42%),在注射速度为16 μL/min和0.1 μL/min时,回收率分别提高到55%和65%。这种增加可能归因于低速率下的全方位位移和高速率下的多指位移,与中速率下观察到的主要指位移形成对比。此外,我们开发了一个双管模型来研究相邻通道在位移过程中的动力机制。在高注入速率下,低粘度流体的增加迅速降低了通道的总体平均粘度,加速了驱替,同时阻碍了邻近通道的驱替过程。相反,在低注入速率下,孔喉连接处毛细力的增加会延迟一个通道的突破,从而促进平行通道的同时位移并确保稳定性。这些发现大大增强了我们对多孔介质中粘性力和毛细力在驱替过程中的相互作用的理解。图形抽象
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引用次数: 0
The dynamics of a reacting polymer attached to a surface 附着在表面上的聚合物的反应动力学
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-12-02 DOI: 10.1140/epje/s10189-024-00464-1
Barry Friedman, Chuck Yeung

Scaling arguments are presented for end-to-wall reaction and end-to-end reactions of grafted chains for non-self-avoiding and self-avoiding chains with and without hydrodynamic interaction. The most realistic minimal model for the experiments of Kim and Lee (J Phys Chem Lett 12:4576, 2021. https://doi.org/10.1021/acs.jpclett.1c00962) is a chain tethered to a plane, the chain having excluded volume and hydrodynamic interaction with end-to-end reactions. From our scaling argument, such a chain obeys a law of mass action where the macroscopic reaction rate is proportional to the microscopic reaction rate multiplied by the probability that the chain ends are close together. More precisely, this means for long chains there is no diffusion controlled limit. In addition, a polymer attached to a plane where the end reacts with the entire plane, end-to-wall reactions, was also investigated. For sufficiently long polymers, this system is always diffusion controlled, even with excluded volume and hydrodynamic interaction. We test the scaling arguments for the simplest case of a non-self-avoiding chains obeying Rouse dynamics. The numerical results agree with the scaling analysis for both end-to-wall and end-to-end reactions of the grafted chain. In particular, our numerical simulations support the end-to-end reaction of a tethered non-self-avoiding is the marginal case in the scaling sense.

提出了接枝链端壁反应和端到端反应的标度参数,适用于有和没有流体动力相互作用的非自避链和自避链。Kim和Lee的实验中最现实的最小模型[J] .物理化学学报,12(5):776,2021。https://doi.org/10.1021/acs.jpclett.1c00962)是拴在平面上的链,链排除了端到端反应的体积和流体动力学相互作用。从我们的标度论证来看,这样的链遵循质量作用定律,即宏观反应速率与微观反应速率乘以链端靠近的概率成正比。更准确地说,这意味着对于长链来说,没有扩散控制的极限。此外,还研究了附着在一个平面上的聚合物,其端部与整个平面发生反应,即端壁反应。对于足够长的聚合物,即使排除了体积和水动力相互作用,该系统也始终是扩散控制的。我们对服从劳斯动力学的非自回避链的最简单情况进行了尺度论证。数值结果与接枝链端到端和端到端反应的标度分析一致。特别是,我们的数值模拟支持端到端反应系绳非自我回避是边际情况下的尺度意义。
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引用次数: 0
A study of novel linear Diophantine fuzzy topological numbers and their application to communicable diseases 新型线性丢番图模糊拓扑数及其在传染病中的应用研究
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-12-01 DOI: 10.1140/epje/s10189-024-00460-5
Siti Norziahidayu Amzee Zamri, Muhammad Azeem, Muhammad Imran, Muhammad Kamran Jamil, Bandar Almohsen

The idea of linear Diophantine fuzzy sets (LDFs) is a novel tool for analysis, soft computing, and optimization. Recently, the concept of a linear Diophantine fuzzy graph has been proposed in 2022. The aim of this research is to extend topological numbers to LDFSs. A real value assigned to a particular graph is known as a topological graph theoretic parameter. We extend the bound of the crisp graph toward the linear Diophantine fuzzy graph (LDFG), including the edge and vertex deletion operations via LDFG theoretic parameters. We also investigate the interesting bound of the LDFGs via LDFG theoretic parameters. Finally, for decision-making problems, we developed an algorithm by exploiting the relationship between LDFG theoretic parameters and LDFSs. Based on the established approach, we discussed a numerical example of an application of a medical diagnosis using the linear Diophantine fuzzy Sombor graph parameter and the first, fifth, and sixth versions of the linear Diophantine fuzzy Sombor graph parameters.

A way to the extension of fuzzy topological numbers.

线性丢番图模糊集的思想是一种新的分析、软计算和优化工具。最近,线性丢番图模糊图的概念在2022年被提出。本研究的目的是将拓扑数扩展到LDFSs。给定给特定图的实值称为拓扑图理论参数。我们将清晰图的界扩展到线性丢芬图(LDFG),包括通过LDFG理论参数的边和顶点删除操作。我们还通过LDFG理论参数研究了LDFG的有趣界。最后,针对决策问题,利用LDFG理论参数与ldfs之间的关系,开发了一种算法。基于所建立的方法,我们讨论了一个使用线性丢芬图模糊Sombor图参数和线性丢芬图模糊Sombor图参数的第一、第五和第六版本的医学诊断应用的数值例子。模糊拓扑数的一种扩展方法。
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引用次数: 0
Universality class of interacting directed single- and double-strand homopolymers 相互作用的定向单链和双链均聚物的普遍性类别
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-11-27 DOI: 10.1140/epje/s10189-024-00461-4
Richard Dengler

This work examines a field theory for directed homopolymers in a good solvent. The field theory is based on a lattice model for single- and double-strand polymers with length variables, direction-dependent pairing energy and interactions. As for the less explicit O(n)-symmetric model, there is a close relation to the conventional one-component branched polymer and the associated Lee-Yang problem. We derive results in the limiting cases of nearly complete denaturation and nearly complete renaturation. The single-strand critical exponent (nu _{varphi }) is calculated in two-loop order. A plausible physical realization is RNA molecules with a periodic base sequence like AUAU.

这项研究探讨了良好溶剂中定向均聚物的场理论。该场理论基于具有长度变量、方向配对能和相互作用的单链和双链聚合物晶格模型。至于不那么明确的 O(n)- 对称模型,则与传统的单组分支化聚合物和相关的李-杨问题有密切关系。我们得出了近乎完全变性和近乎完全再变性的极限情况下的结果。单链临界指数 (nu _{varphi }) 是以双环阶计算的。具有类似 AUAU 周期性碱基序列的 RNA 分子是一种可信的物理实现。
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引用次数: 0
Modeling straight and circle swimmers: from single swimmer to collective motion 直泳和环泳运动员建模:从单泳到集体运动
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-11-18 DOI: 10.1140/epje/s10189-024-00458-z
Francesco Michele Ventrella, Guido Boffetta, Massimo Cencini, Filippo De Lillo

We propose a simple numerical model for the motion of microswimmers based on the immersed boundary method. The swimmer, either pusher or puller, is represented by a distribution of point forces corresponding to the body and the flagellum. We study in particular the minimal model consisting of only three beads (two for the body and one for the flagellum) connected by rigid, inextensible links. When the beads are collinear, standard straight swimming is realized and, in the absence of propulsion, we demonstrate that the model recovers Jeffery’s equation for a thin rod. Conversely, by imposing an angle between body and flagellum the swimmer moves on circular orbits. We discuss how two swimmers, in collinear or non-collinear geometry, scatter upon encounter. Finally, we explore the dynamics of a large number of swimmers reacting to one another only via hydrodynamic interactions, and exemplify their complex collective dynamics in both straight and circular swimmers.

我们提出了一种基于沉浸边界法的微型游泳者运动的简单数值模型。游泳者,无论是推动者还是牵引者,都由与身体和鞭毛相对应的点力分布来表示。我们特别研究了仅由三颗珠子(两颗代表身体,一颗代表鞭毛)组成的最小模型,这三颗珠子由刚性、不可拉伸的链接连接。当珠子相互平行时,可实现标准的直线游动,在没有推进力的情况下,我们证明该模型恢复了杰弗里方程中的细杆。相反,如果在身体和鞭毛之间施加一个角度,游泳者就会在圆形轨道上运动。我们讨论了两个处于共线或非共线几何形状中的游泳者如何在相遇时分散。最后,我们探讨了大量游动体仅通过流体动力学相互作用相互反应的动力学,并举例说明了直线游动体和环形游动体的复杂集体动力学。
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引用次数: 0
Multibody interactions between protein inclusions in the pointlike curvature model for tense and tensionless membranes 张力膜和无张力膜的点状曲率模型中蛋白质内含物之间的多体相互作用
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-10-16 DOI: 10.1140/epje/s10189-024-00456-1
Jean-Baptiste Fournier

The pointlike curvature constraint (PCC) model and the disk detachment angle (DDA) model for the deformation-mediated interaction of conical integral protein inclusions in biomembranes are compared in the small deformation regime. Given the radius of membrane proteins, which is comparable to the membrane thickness, it is not obvious which of the two models should be considered the most adequate. For two proteins in a tensionless membranes, the PCC and DDA models coincide at the leading-order (sim r^{-4}) in their separation but differ at the next order. Yet, for distances larger than twice the proteins diameter, the difference is less than (10%). Like the DDA model, the PCC model includes all multibody interactions in a non-approximate way. The asymptotic (sim r^{-4}) many-body energy of triangular and square protein clusters is exactly the same in both models. Pentagonal clusters, however, behave differently; they have a vanishing energy in the PCC model, while they have a non-vanishing weaker (sim r^{-6}) asymptotic power law in the DDA model. We quantify the importance of multibody interactions in small polygonal clusters of three, four and five inclusions with identical or opposite curvatures in tensionless or tense membranes. We find that the pairwise approximation is almost always very poor. At short separation, the three-body interaction is not sufficient to account for the full many-body interaction. This is confirmed by equilibrium Monte Carlo simulations of up to ten inclusions.

在小变形机制下,比较了生物膜中锥形整体蛋白质内含物变形介导相互作用的点状曲率约束(PCC)模型和圆盘脱离角(DDA)模型。考虑到膜蛋白的半径与膜厚度相当,两种模型中哪一种最合适并不明显。对于无张力膜中的两个蛋白质,PCC模型和DDA模型在其分离的前阶(sim r^{-4})上是一致的,但在后阶上则不同。然而,对于大于两倍蛋白质直径的距离,两者的差异小于(10%)。与 DDA 模型一样,PCC 模型以一种非近似的方式包含了所有多体相互作用。在这两种模型中,三角形和正方形蛋白质团簇的多体能量的渐近((sim r^{-4}))是完全一样的。然而,五角形集群的表现却不同;在PCC模型中,它们的能量是消失的,而在DDA模型中,它们的渐近幂律是非消失的弱(sim r^{-6})。我们量化了在无张力膜或有张力膜中由三个、四个和五个具有相同或相反曲率的夹杂物组成的多边形小簇中多体相互作用的重要性。我们发现,成对近似几乎总是很差。在短距离内,三体相互作用不足以解释全部的多体相互作用。多达十个夹杂物的平衡蒙特卡罗模拟证实了这一点。
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引用次数: 0
Research on sedimentation characteristics of squirmer in a power-law fluid 幂律流体中蜗杆的沉降特性研究
IF 1.8 4区 物理与天体物理 Q4 CHEMISTRY, PHYSICAL Pub Date : 2024-10-15 DOI: 10.1140/epje/s10189-024-00457-0
Amin Ullah, Jianzhong Lin, Yuxiang Yin

Sedimentation characteristics of a squirmer in a power-law fluid within a vertical channel are studied numerically using the two-dimensional lattice Boltzmann method. The effects of swimming type (− 5 ≤ β ≤ 5), self-propelling strength (0.5 ≤ α ≤ 1.1), power-law indexes (0.5 ≤ n ≤ 1.5), and the density ratio of the squirmer to the fluid (γ = 1.01, 1.5 and 2.3) on the sedimentation of the squirmer are analyzed. Four settlement patterns are identified: steady falling in the center, downward along the wall, oscillating with large amplitude and oscillating around the centerline. The squirmer in the channel exhibits more fluctuations in shear-thinning (n < 1) and Newtonian (n = 1) fluids compared to shear-thickening fluids (n > 1). Additionally, a puller (β > 0) settles faster than a pusher (β < 0) in shear-thinning and Newtonian fluids. Puller generates flow towards their head and away from their tail, exhibiting small amplitude oscillations. Pushers exhibit higher amplitude oscillations throughout the channel, creating flow towards their tail and away from their head. At lower γ, the fluctuation of the squirmer is less pronounced compared to higher γ.

Graphical abstract

采用二维晶格玻尔兹曼方法对垂直通道内幂律流体中的蜗牛沉积特性进行了数值研究。分析了游动类型(- 5 ≤ β ≤ 5)、自推进强度(0.5 ≤ α ≤ 1.1)、幂律指数(0.5 ≤ n ≤ 1.5)和松鼠与流体的密度比(γ = 1.01、1.5 和 2.3)对松鼠沉降的影响。确定了四种沉降模式:中心稳定下降、沿壁向下沉降、大振幅振荡和绕中心线振荡。与剪切增稠流体(n >1)相比,在剪切稀化流体(n <1)和牛顿流体(n = 1)中,水槽中的唧筒表现出更大的波动。此外,在剪切稀化流体和牛顿流体中,牵引器(β >0)的沉降速度快于推流器(β <0)。拉力器产生流向头部和远离尾部的流动,表现出小振幅振荡。推流器在整个通道中表现出较高的振幅振荡,产生流向尾部和远离头部的流动。γ值较低时,推流器的波动没有γ值较高时明显。
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引用次数: 0
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The European Physical Journal E
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