首页 > 最新文献

Annals of Gastroenterological Surgery最新文献

英文 中文
Inter-prefectural and urban–rural regional disparities in rectal cancer and rectal resections: A Japanese nationwide population-based cohort study from 2014 to 2019 直肠癌和直肠切除术的县际和城乡地区差异:2014年至2019年日本全国人口队列研究
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 DOI: 10.1002/ags3.12865
Masamitsu Kido, Tomohiro Arita, Katsutoshi Shoda, Hiroki Shimizu, Jun Kiuchi, Kenji Nanishi, Luying Yan, Eigo Otsuji

Aim

This observational study aimed to elucidate the regional disparities in rectal cancer (RC) and rectal resections (RRs) across Japan.

Methods

The annual incidence of RC, and number of all RRs and board-certified surgeons by the Japan Society for Endoscopic Surgery were examined by prefecture in Japan from 2014 to 2019. The surgical approaches were broken down by open and laparoscopic. Disparities in 47 prefectures and urban–rural disparities were evaluated using the Gini coefficient and unpaired t-test.

Results

The annual national average incidence of RC was 50 127 and the number of all RRs was 39 903. Gini coefficients for RC, and laparoscopic and all RRs were <0.2, indicating low inequality. There was no significant difference between urban and rural prefectures in the number of RRs, despite a significantly higher incidence of RC in rural prefectures and a significantly higher number of board-certified surgeons in urban prefectures (p < 0.05).

Conclusion

RC and laparoscopic and all RRs exhibited minimal inter-prefectural disparities. The urban–rural analysis revealed significant differences in the incidence/number of RC and board-certified surgeons between urban and rural prefectures, despite minor differences in RRs regardless of approach. This pattern suggests a potential migration of surgical services from rural to urban areas. This preliminary study is expected to contribute to a basic epidemiological database for RC and RRs.

{"title":"Inter-prefectural and urban–rural regional disparities in rectal cancer and rectal resections: A Japanese nationwide population-based cohort study from 2014 to 2019","authors":"Masamitsu Kido,&nbsp;Tomohiro Arita,&nbsp;Katsutoshi Shoda,&nbsp;Hiroki Shimizu,&nbsp;Jun Kiuchi,&nbsp;Kenji Nanishi,&nbsp;Luying Yan,&nbsp;Eigo Otsuji","doi":"10.1002/ags3.12865","DOIUrl":"https://doi.org/10.1002/ags3.12865","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This observational study aimed to elucidate the regional disparities in rectal cancer (RC) and rectal resections (RRs) across Japan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The annual incidence of RC, and number of all RRs and board-certified surgeons by the Japan Society for Endoscopic Surgery were examined by prefecture in Japan from 2014 to 2019. The surgical approaches were broken down by open and laparoscopic. Disparities in 47 prefectures and urban–rural disparities were evaluated using the Gini coefficient and unpaired <i>t</i>-test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The annual national average incidence of RC was 50 127 and the number of all RRs was 39 903. Gini coefficients for RC, and laparoscopic and all RRs were &lt;0.2, indicating low inequality. There was no significant difference between urban and rural prefectures in the number of RRs, despite a significantly higher incidence of RC in rural prefectures and a significantly higher number of board-certified surgeons in urban prefectures (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>RC and laparoscopic and all RRs exhibited minimal inter-prefectural disparities. The urban–rural analysis revealed significant differences in the incidence/number of RC and board-certified surgeons between urban and rural prefectures, despite minor differences in RRs regardless of approach. This pattern suggests a potential migration of surgical services from rural to urban areas. This preliminary study is expected to contribute to a basic epidemiological database for RC and RRs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 2","pages":"281-287"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ags3.12865","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer 通过免疫染色诊断的浸液细胞学可能是病理Ⅲ期结直肠癌的不良预后因素
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 DOI: 10.1002/ags3.12863
Akitoshi Nankaku, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Shoichi Manabe, Takuma Oishi, Kiyoshi Tone, Akifumi Notsu, Yusuke Kinugasa

Aim

To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long-term outcomes following curative resection for pathological stage III colorectal cancer (CRC).

Method

We retrospectively investigated patients who underwent radical resection and intraoperative lavage cytology (LCY) simultaneously for pathological stage III primary CRC between 2005 and 2017. All LCY specimens were evaluated by Papanicolaou staining and immunostaining for carcinoembryonic antigen and Ber-EP4. Only Class V diagnosed by either staining method was defined as positive LCY, and patients were classified into two groups: a positive lavage cytology (LCY+) group; and a negative lavage cytology (LCY−) group. Overall survival (OS) and relapse-free survival (RFS) were compared between groups. Multivariate analysis was performed to identify clinicopathological factors affecting OS and RFS.

Results

Among 708 patients with pathological stage III CRC, 30 patients (4.2%) showed positive LCY. OS and RFS were significantly lower in the LCY(+) group than in the LCY(−) group. Five-y OS rates in the LCY(+) and LCY(−) groups were 58.7% and 91.0%, respectively, and 5-y RFS rates were 28.8% and 76.6%, respectively. Multivariate analysis revealed that positive LCY was independently associated with lower OS and RFS. In the LCY(+) group, the proportion of patients with negative Papanicolaou staining but positive immunostaining was 20.0% (6 of 30). No significant differences in OS and RFS were evident between those patients and patients with positive results for both Papanicolaou staining and immunostaining.

Conclusion

Positive LCY as diagnosed by immunostaining may represent a poor prognostic factor for pathological stage III CRC.

{"title":"Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer","authors":"Akitoshi Nankaku,&nbsp;Yusuke Yamaoka,&nbsp;Akio Shiomi,&nbsp;Hiroyasu Kagawa,&nbsp;Shoichi Manabe,&nbsp;Takuma Oishi,&nbsp;Kiyoshi Tone,&nbsp;Akifumi Notsu,&nbsp;Yusuke Kinugasa","doi":"10.1002/ags3.12863","DOIUrl":"https://doi.org/10.1002/ags3.12863","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long-term outcomes following curative resection for pathological stage III colorectal cancer (CRC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>We retrospectively investigated patients who underwent radical resection and intraoperative lavage cytology (LCY) simultaneously for pathological stage III primary CRC between 2005 and 2017. All LCY specimens were evaluated by Papanicolaou staining and immunostaining for carcinoembryonic antigen and Ber-EP4. Only Class V diagnosed by either staining method was defined as positive LCY, and patients were classified into two groups: a positive lavage cytology (LCY+) group; and a negative lavage cytology (LCY−) group. Overall survival (OS) and relapse-free survival (RFS) were compared between groups. Multivariate analysis was performed to identify clinicopathological factors affecting OS and RFS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 708 patients with pathological stage III CRC, 30 patients (4.2%) showed positive LCY. OS and RFS were significantly lower in the LCY(+) group than in the LCY(−) group. Five-y OS rates in the LCY(+) and LCY(−) groups were 58.7% and 91.0%, respectively, and 5-y RFS rates were 28.8% and 76.6%, respectively. Multivariate analysis revealed that positive LCY was independently associated with lower OS and RFS. In the LCY(+) group, the proportion of patients with negative Papanicolaou staining but positive immunostaining was 20.0% (6 of 30). No significant differences in OS and RFS were evident between those patients and patients with positive results for both Papanicolaou staining and immunostaining.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Positive LCY as diagnosed by immunostaining may represent a poor prognostic factor for pathological stage III CRC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 2","pages":"271-280"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ags3.12863","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
y-shaped side overlap esophagogastrostomy in proximal gastrectomy 近端胃切除术中y型侧重叠食管胃造口术。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-17 DOI: 10.1002/ags3.12859
Yukinori Kurokawa, Takuro Saito, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Yuichiro Doki

Several reconstruction methods are used in proximal gastrectomy. Esophagogastrostomy is the simplest and most physiological. The challenge in esophagogastrostomy is preventing reflux esophagitis. Various techniques have been developed to reduce reflux of gastric juice. Taking advantage of the usefulness of the recently reported modified side overlap with fundoplication by Yamashita (mSOFY) method, we developed a y-shaped mSOFY method that is simpler and has potential for a greater anti-reflux effect. Unlike the original mSOFY method, the pseudo-fornix does not go behind the esophagus and the axes of the esophagus and residual stomach are shifted by approximately 60° to form a “y” shape. In addition, fixation of the residual stomach and both sides of the esophagus and crus of the diaphragm is performed at the end of the procedure. We performed 12 cases of laparoscopic or robotic proximal gastrectomy with y-shaped mSOFY esophagogastric anastomosis located below the crus of the diaphragm for gastric or esophagogastric junction adenocarcinoma between August 2021 and March 2023. The median operative time and blood loss were 260 min and 5 mL, respectively. No postoperative complications of Clavien–Dindo classification grade II or higher occurred. No stenoses requiring balloon dilation occurred within 1 year after surgery, but endoscopy at 1 year after surgery revealed two cases (17%) of reflux esophagitis of Los Angeles grade B or higher. In conclusion, this y-shaped side overlap esophagogastrostomy method could be one of the recommended esophagogastrostomy procedures in proximal gastrectomy.

胃近端切除术中有几种重建方法。食管胃造口术是最简单和最生理的。食管胃造口术的挑战是防止反流性食管炎。已经发展了各种技术来减少胃液反流。利用最近报道的Yamashita (mSOFY)方法的改良侧重叠与眼底重叠的有用性,我们开发了一种更简单且具有更大抗反流效果的y形mSOFY方法。与最初的mSOFY方法不同,假穹窿不位于食管后面,食管和残余胃的轴线移动约60°,形成“y”形。此外,在手术结束时,对残余胃、食管两侧和膈肌小腿进行固定。我们在2021年8月至2023年3月期间对12例胃或食管胃交界处腺癌进行了腹腔镜或机器人胃近端切除术,并在膈脚下进行了y形mSOFY食管胃吻合术。中位手术时间260 min,出血量5 mL。术后无Clavien-Dindo分级II级及以上并发症发生。术后1年内未发生需要球囊扩张的狭窄,但术后1年内窥镜检查发现2例(17%)反流性食管炎,洛杉矶分级为B级或更高。综上所述,这种y型侧重叠食管胃造口方法可作为近端胃切除术中推荐的食管胃造口方法之一。
{"title":"y-shaped side overlap esophagogastrostomy in proximal gastrectomy","authors":"Yukinori Kurokawa,&nbsp;Takuro Saito,&nbsp;Kazuyoshi Yamamoto,&nbsp;Tsuyoshi Takahashi,&nbsp;Yuichiro Doki","doi":"10.1002/ags3.12859","DOIUrl":"10.1002/ags3.12859","url":null,"abstract":"<p>Several reconstruction methods are used in proximal gastrectomy. Esophagogastrostomy is the simplest and most physiological. The challenge in esophagogastrostomy is preventing reflux esophagitis. Various techniques have been developed to reduce reflux of gastric juice. Taking advantage of the usefulness of the recently reported modified side overlap with fundoplication by Yamashita (mSOFY) method, we developed a y-shaped mSOFY method that is simpler and has potential for a greater anti-reflux effect. Unlike the original mSOFY method, the pseudo-fornix does not go behind the esophagus and the axes of the esophagus and residual stomach are shifted by approximately 60° to form a “y” shape. In addition, fixation of the residual stomach and both sides of the esophagus and crus of the diaphragm is performed at the end of the procedure. We performed 12 cases of laparoscopic or robotic proximal gastrectomy with y-shaped mSOFY esophagogastric anastomosis located below the crus of the diaphragm for gastric or esophagogastric junction adenocarcinoma between August 2021 and March 2023. The median operative time and blood loss were 260 min and 5 mL, respectively. No postoperative complications of Clavien–Dindo classification grade II or higher occurred. No stenoses requiring balloon dilation occurred within 1 year after surgery, but endoscopy at 1 year after surgery revealed two cases (17%) of reflux esophagitis of Los Angeles grade B or higher. In conclusion, this y-shaped side overlap esophagogastrostomy method could be one of the recommended esophagogastrostomy procedures in proximal gastrectomy.</p>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"205-210"},"PeriodicalIF":2.9,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic esophagectomy with function-preserving radical mediastinal lymphadenectomy for esophageal cancer 机器人食管切除术联合保留功能的纵隔淋巴结根治术治疗食管癌。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-11 DOI: 10.1002/ags3.12862
Raja Kalayarasan, Pothugunta Sai Krishna

Radical lymphadenectomy is the critical component of surgery for esophageal cancer. However, lymphadenectomy significantly contributes to postoperative morbidity, particularly in terms of pulmonary complications following esophagectomy. Function-preserving mediastinal lymphadenectomy seeks to balance the procedure's necessary radicality and optimal functional outcomes. This approach emphasizes the preservation of the thoracic duct, tracheobronchial vascularity, and the pulmonary and recurrent laryngeal branches of the vagus nerve. Preservation of the thoracic duct is facilitated by indocyanine green fluorescence. Compared to the conventional technique of thoracic duct identification using anatomical landmarks, indocyanine green fluorescence lymphangiography offers real-time feedback, making it particularly advantageous in cases with complex anatomy or when the thoracic duct is challenging to visualize using conventional methods. Preservation of pulmonary branches of the right vagus during subcarinal lymphadenectomy and left recurrent laryngeal nerve during left paratracheal node dissection are technically challenging. The description of two types of left recurrent laryngeal nerve node dissection and technical tips for nerve function preservation are outlined in this review. Intraoperative neuromonitoring is a useful adjunct for nerve-sparing mediastinal lymphadenectomy. As ischemia to the respiratory tract impairs respiratory protective mechanisms, preservation of the tracheobronchial blood supply is critical. Preoperative imaging to detect bronchial artery anatomical variations and intraoperative assessment of perfusion using laser doppler flowmetry and indocyanine green fluorescence angiography are useful strategies to minimize tracheobronchial ischemia. Function-preserving mediastinal lymphadenectomy has the potential to improve short- and long-term outcomes after esophagectomy for esophageal cancer.

根治性淋巴结切除术是食管癌手术的重要组成部分。然而,淋巴结切除术显著增加了术后发病率,特别是在食管切除术后的肺部并发症方面。功能保留纵隔淋巴结切除术寻求平衡手术的必要的根治性和最佳的功能结果。该入路强调保留胸导管、气管支气管血管、迷走神经的肺支和喉返支。吲哚菁绿荧光有助于保存胸导管。与传统的利用解剖标志识别胸导管的技术相比,吲哚菁绿荧光淋巴管造影提供实时反馈,在解剖结构复杂或使用传统方法难以可视化胸导管的情况下尤其有利。在隆突下淋巴结切除术中保留右侧迷走神经肺分支,在左侧气管旁淋巴结清扫术中保留左侧喉返神经在技术上具有挑战性。本文概述了两种类型的左喉返神经节清扫术和保存神经功能的技术技巧。术中神经监测是保留神经的纵隔淋巴结切除术的有效辅助手段。由于呼吸道缺血会损害呼吸保护机制,因此保持气管支气管的血液供应至关重要。术前影像学检查支气管动脉解剖变化,术中应用激光多普勒血流仪和吲哚菁绿荧光血管造影评估灌注是减少气管支气管缺血的有效策略。保留功能的纵隔淋巴结切除术有可能改善食管癌切除术后的短期和长期预后。
{"title":"Robotic esophagectomy with function-preserving radical mediastinal lymphadenectomy for esophageal cancer","authors":"Raja Kalayarasan,&nbsp;Pothugunta Sai Krishna","doi":"10.1002/ags3.12862","DOIUrl":"10.1002/ags3.12862","url":null,"abstract":"<p>Radical lymphadenectomy is the critical component of surgery for esophageal cancer. However, lymphadenectomy significantly contributes to postoperative morbidity, particularly in terms of pulmonary complications following esophagectomy. Function-preserving mediastinal lymphadenectomy seeks to balance the procedure's necessary radicality and optimal functional outcomes. This approach emphasizes the preservation of the thoracic duct, tracheobronchial vascularity, and the pulmonary and recurrent laryngeal branches of the vagus nerve. Preservation of the thoracic duct is facilitated by indocyanine green fluorescence. Compared to the conventional technique of thoracic duct identification using anatomical landmarks, indocyanine green fluorescence lymphangiography offers real-time feedback, making it particularly advantageous in cases with complex anatomy or when the thoracic duct is challenging to visualize using conventional methods. Preservation of pulmonary branches of the right vagus during subcarinal lymphadenectomy and left recurrent laryngeal nerve during left paratracheal node dissection are technically challenging. The description of two types of left recurrent laryngeal nerve node dissection and technical tips for nerve function preservation are outlined in this review. Intraoperative neuromonitoring is a useful adjunct for nerve-sparing mediastinal lymphadenectomy. As ischemia to the respiratory tract impairs respiratory protective mechanisms, preservation of the tracheobronchial blood supply is critical. Preoperative imaging to detect bronchial artery anatomical variations and intraoperative assessment of perfusion using laser doppler flowmetry and indocyanine green fluorescence angiography are useful strategies to minimize tracheobronchial ischemia. Function-preserving mediastinal lymphadenectomy has the potential to improve short- and long-term outcomes after esophagectomy for esophageal cancer.</p>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"12-23"},"PeriodicalIF":2.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic median arcuate ligament release using an anterior approach for median arcuate ligament syndrome 腹腔镜正中弓状韧带松解术,采用前路治疗正中弓状韧带综合征。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-10 DOI: 10.1002/ags3.12858
Koji Kubota, Akira Shimizu, Tsuyoshi Notake, Satoshi Nakamura, Yuji Soejima

Median arcuate ligament syndrome (MALS) is a rare condition characterized by nonspecific symptoms, such as abdominal pain, nausea, and vomiting. Furthermore, the development and rupture of pancreaticoduodenal artery aneurysms pose a potentially fatal risk. Median arcuate ligament release (MALR) is useful in the treatment of MALS, with most procedures performed laparoscopically. However, detailed descriptions of laparoscopic MALR (lap-MALR) procedures are rare. In this study, we performed lap-MALR via an anterior approach with dissection of the right lateral wall of the celiac artery (CA). For optimal visualization of the right side of the CA, the right branch of the inferior phrenic artery was divided. We believe that this procedure allows the MAL to be released within a sufficient surgical field and without excess or deficiency. Here, we present the details of six patients who underwent lap-MALR for varying indications; three for pancreaticoduodenal artery aneurysms due to CA obstruction (unruptured, n = 1; ruptured, n = 2), two cases prior to hepato-biliary-pancreatic surgery, and one symptomatic case. In all cases, lap-MALR was performed as described above, and the CA stenosis was successfully released. Our case series demonstrates the safety and reliability of our lap-MALR procedure in the treatment of MALS-related disorders, including pancreaticoduodenal artery aneurysms associated with CA compression.

弧中韧带综合征(MALS)是一种罕见疾病,以腹痛、恶心和呕吐等非特异性症状为特征。此外,胰十二指肠动脉瘤的发生和破裂可能带来致命风险。正中弓状韧带松解术(MALR)可用于治疗 MALS,大多数手术都是在腹腔镜下进行的。然而,有关腹腔镜 MALR(腹腔镜 MALR)手术的详细描述并不多见。在本研究中,我们通过腹腔前路进行腹腔镜 MALR,并对腹腔动脉(CA)右侧壁进行解剖。为了获得腹腔动脉右侧的最佳视野,我们分割了膈下动脉的右侧分支。我们认为,这种手术方法可以在足够的手术视野内释放 MAL,且不会出现多余或不足的情况。在此,我们介绍了六例因不同适应症而接受腹腔镜-MALR的患者的详细情况,其中三例是因CA阻塞导致的胰十二指肠动脉瘤(未破裂,1例;破裂,2例),两例是在肝胆胰手术之前,还有一例是无症状病例。在所有病例中,都按照上述方法进行了腹腔镜-MALR,并成功解除了CA狭窄。我们的病例系列证明了腹腔镜-MALR术在治疗MALS相关疾病(包括与CA压迫相关的胰十二指肠动脉瘤)方面的安全性和可靠性。
{"title":"Laparoscopic median arcuate ligament release using an anterior approach for median arcuate ligament syndrome","authors":"Koji Kubota,&nbsp;Akira Shimizu,&nbsp;Tsuyoshi Notake,&nbsp;Satoshi Nakamura,&nbsp;Yuji Soejima","doi":"10.1002/ags3.12858","DOIUrl":"10.1002/ags3.12858","url":null,"abstract":"<p>Median arcuate ligament syndrome (MALS) is a rare condition characterized by nonspecific symptoms, such as abdominal pain, nausea, and vomiting. Furthermore, the development and rupture of pancreaticoduodenal artery aneurysms pose a potentially fatal risk. Median arcuate ligament release (MALR) is useful in the treatment of MALS, with most procedures performed laparoscopically. However, detailed descriptions of laparoscopic MALR (lap-MALR) procedures are rare. In this study, we performed lap-MALR via an anterior approach with dissection of the right lateral wall of the celiac artery (CA). For optimal visualization of the right side of the CA, the right branch of the inferior phrenic artery was divided. We believe that this procedure allows the MAL to be released within a sufficient surgical field and without excess or deficiency. Here, we present the details of six patients who underwent lap-MALR for varying indications; three for pancreaticoduodenal artery aneurysms due to CA obstruction (unruptured, <i>n</i> = 1; ruptured, <i>n</i> = 2), two cases prior to hepato-biliary-pancreatic surgery, and one symptomatic case. In all cases, lap-MALR was performed as described above, and the CA stenosis was successfully released. Our case series demonstrates the safety and reliability of our lap-MALR procedure in the treatment of MALS-related disorders, including pancreaticoduodenal artery aneurysms associated with CA compression.</p>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"8 6","pages":"1137-1143"},"PeriodicalIF":2.9,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11533021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142580797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic right-sided colon cancer surgery: Dissecting the outermost layer of the autonomic nerve along the superior mesenteric artery 机器人右侧结肠癌手术:沿着肠系膜上动脉剥离自主神经的最外层。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-09 DOI: 10.1002/ags3.12861
Dai Shida, Yuka Ahiko, Naoki Sakuyama, Satoko Monma, Shigehiro Kojima

In right-sided colon cancer surgery, lymph node dissection around the superior mesenteric artery is necessary but technically challenging. Here we introduce the concept of “outermost layer-oriented robotic surgery” to improve the safety, efficacy, and reproducibility of superior mesenteric artery nodal dissection. In this procedure, the thin, loose connective tissue layer between the autonomic nerve sheath of the superior mesenteric artery and adipose tissue bearing lymph nodes, termed “the outermost layer of the autonomic nerve,” is dissected. The procedure exposes the outermost layer of the nerve plexus covering the surface of the superior mesenteric artery with a width of approximately 1 cm, enabling direct visualization of the anatomy of the main arteries and, if they exist, jejunal veins which cross the superior mesenteric artery ventrally. This allows for sufficient dissection of main lymph nodes at the roots of the ileocolic artery, right colic artery, and middle colic artery and minimizes the risk of unforeseen bleeding. Thirty-nine patients underwent robotic right hemicolectomy with this procedure. No intraoperative complications were observed. The median number of dissected lymph nodes was 50, including 16 main lymph nodes. The median operative time was 284 min, blood loss was 50 mL, and the median postoperative hospital stay was 8 days. Postoperative complications included two cases of Clavien–Dindo classification grade II, with no cases of grade III or higher. Chylous leakage as well as intractable diarrhea were not observed in any case. These findings demonstrate that the procedure can achieve safe and reliable lymph node clearance.

在右侧结肠癌手术中,肠系膜上动脉周围的淋巴结清扫是必要的,但技术上具有挑战性。在这里,我们引入“最外层导向机器人手术”的概念,以提高肠系膜上动脉淋巴结清扫的安全性、有效性和可重复性。在这个过程中,切开肠系膜上动脉的自主神经鞘和含有淋巴结的脂肪组织之间的薄而松散的结缔组织层,称为“自主神经的最外层”。该方法暴露了覆盖肠系膜上动脉表面的神经丛最外层,宽度约为1cm,可以直接看到主要动脉的解剖结构,如果存在的话,还可以看到腹侧穿过肠系膜上动脉的空肠静脉。这样可以充分剥离回结肠动脉、右结肠动脉和中结肠动脉根部的主要淋巴结,并将意外出血的风险降至最低。39例患者接受了机器人右半结肠切除术。无术中并发症。清扫淋巴结中位数为50个,其中主淋巴结16个。中位手术时间284 min,出血量50 mL,术后中位住院时间8 d。术后并发症包括2例Clavien-Dindo分级II级,无III级及以上病例。乳糜漏及顽固性腹泻均未见。这些结果表明,该手术可以实现安全可靠的淋巴结清除。
{"title":"Robotic right-sided colon cancer surgery: Dissecting the outermost layer of the autonomic nerve along the superior mesenteric artery","authors":"Dai Shida,&nbsp;Yuka Ahiko,&nbsp;Naoki Sakuyama,&nbsp;Satoko Monma,&nbsp;Shigehiro Kojima","doi":"10.1002/ags3.12861","DOIUrl":"10.1002/ags3.12861","url":null,"abstract":"<p>In right-sided colon cancer surgery, lymph node dissection around the superior mesenteric artery is necessary but technically challenging. Here we introduce the concept of “outermost layer-oriented robotic surgery” to improve the safety, efficacy, and reproducibility of superior mesenteric artery nodal dissection. In this procedure, the thin, loose connective tissue layer between the autonomic nerve sheath of the superior mesenteric artery and adipose tissue bearing lymph nodes, termed “the outermost layer of the autonomic nerve,” is dissected. The procedure exposes the outermost layer of the nerve plexus covering the surface of the superior mesenteric artery with a width of approximately 1 cm, enabling direct visualization of the anatomy of the main arteries and, if they exist, jejunal veins which cross the superior mesenteric artery ventrally. This allows for sufficient dissection of main lymph nodes at the roots of the ileocolic artery, right colic artery, and middle colic artery and minimizes the risk of unforeseen bleeding. Thirty-nine patients underwent robotic right hemicolectomy with this procedure. No intraoperative complications were observed. The median number of dissected lymph nodes was 50, including 16 main lymph nodes. The median operative time was 284 min, blood loss was 50 mL, and the median postoperative hospital stay was 8 days. Postoperative complications included two cases of Clavien–Dindo classification grade II, with no cases of grade III or higher. Chylous leakage as well as intractable diarrhea were not observed in any case. These findings demonstrate that the procedure can achieve safe and reliable lymph node clearance.</p>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"199-204"},"PeriodicalIF":2.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digestive tract reconstruction after laparoscopic proximal gastrectomy: Double tract reconstruction or double flap technique? 腹腔镜胃近端切除术后消化道重建:双道重建还是双瓣技术?
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-09-01 DOI: 10.1002/ags3.12857
Lindi Cai, Guanglin Qiu, Mengke Zhu, Shangning Han, Pengwei Zhao, Panxing Wang, Xiaowen Li, Xinhua Liao, Xiangming Che, Lin Fan

Aim

The reconstruction methods after proximal gastrectomy (PG) are varied but not standardized. This study was performed to evaluate the short-term clinical outcomes between double tract reconstruction (DTR) and double flap technique (DFT).

Methods

We retrospectively reviewed and collected data of patients who underwent DTR and DFT after laparoscopic proximal gastrectomy (LPG), respectively, between January 2020 and March 2023. Propensity score matching (PSM) was used to balance the baseline data of the two groups, then we compared their short-term clinical outcomes.

Results

A total of 72 patients (48 and 24 patients in the DTR and DFT groups, respectively) were included. The anastomosis time was significantly longer in the DFT group than that in the DTR group (70.1 vs. 52.7 min, p < 0.001). DFT was associated with shorter times of gas-passing, start of diet, and postoperative length of hospital stay (p < 0.001). There were no significant differences between the two groups in terms of early and late postoperative complications (p = 0.710, p = 1.000, respectively). DFT was superior to DTR in maintaining body weight (p < 0.001), total protein (p = 0.011) and albumin levels (p = 0.018). As for QOL, DTR showed better results in the meal-related distress subscale (p < 0.001). However, DFT was superior to DTR in terms of reducing diarrhea, constipation, and dumping related symptoms (p < 0.05).

Conclusion

Double flap technique emerged as a superior alternative to DTR in terms of facilitating early postoperative recovery, sustaining nutritional status, and improving QOL. DFT could potentially be the preferred reconstruction method following laparoscopic proximal gastrectomy.

目的:胃近端切除术后重建方法多样,但不规范。本研究旨在评估双束重建术(DTR)与双瓣技术(DFT)的短期临床效果。方法:我们回顾性分析并收集了2020年1月至2023年3月期间腹腔镜近端胃切除术(LPG)后分别行DTR和DFT的患者数据。采用倾向评分匹配法(PSM)平衡两组基线数据,比较两组近期临床结果。结果:共纳入72例患者(DTR组48例,DFT组24例)。DFT组吻合时间明显长于DTR组(70.1 min vs. 52.7 min, p p p = 0.710, p = 1.000)。DFT在维持体重(p = 0.011)和白蛋白水平(p = 0.018)方面优于DTR。在生活质量方面,DTR在膳食相关窘迫分量表中表现出更好的效果(p p)。结论:双瓣技术在促进术后早期恢复、维持营养状态和提高生活质量方面优于DTR。DFT可能是腹腔镜胃近端切除术后首选的重建方法。
{"title":"Digestive tract reconstruction after laparoscopic proximal gastrectomy: Double tract reconstruction or double flap technique?","authors":"Lindi Cai,&nbsp;Guanglin Qiu,&nbsp;Mengke Zhu,&nbsp;Shangning Han,&nbsp;Pengwei Zhao,&nbsp;Panxing Wang,&nbsp;Xiaowen Li,&nbsp;Xinhua Liao,&nbsp;Xiangming Che,&nbsp;Lin Fan","doi":"10.1002/ags3.12857","DOIUrl":"10.1002/ags3.12857","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The reconstruction methods after proximal gastrectomy (PG) are varied but not standardized. This study was performed to evaluate the short-term clinical outcomes between double tract reconstruction (DTR) and double flap technique (DFT).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively reviewed and collected data of patients who underwent DTR and DFT after laparoscopic proximal gastrectomy (LPG), respectively, between January 2020 and March 2023. Propensity score matching (PSM) was used to balance the baseline data of the two groups, then we compared their short-term clinical outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 72 patients (48 and 24 patients in the DTR and DFT groups, respectively) were included. The anastomosis time was significantly longer in the DFT group than that in the DTR group (70.1 vs. 52.7 min, <i>p</i> &lt; 0.001). DFT was associated with shorter times of gas-passing, start of diet, and postoperative length of hospital stay (<i>p</i> &lt; 0.001). There were no significant differences between the two groups in terms of early and late postoperative complications (<i>p</i> = 0.710, <i>p</i> = 1.000, respectively). DFT was superior to DTR in maintaining body weight (<i>p</i> &lt; 0.001), total protein (<i>p</i> = 0.011) and albumin levels (<i>p</i> = 0.018). As for QOL, DTR showed better results in the meal-related distress subscale (<i>p</i> &lt; 0.001). However, DFT was superior to DTR in terms of reducing diarrhea, constipation, and dumping related symptoms (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Double flap technique emerged as a superior alternative to DTR in terms of facilitating early postoperative recovery, sustaining nutritional status, and improving QOL. DFT could potentially be the preferred reconstruction method following laparoscopic proximal gastrectomy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"98-108"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraluminal washout in rectal and sigmoid colon cancer surgeries with double-stapling technique anastomosis: A single-institution prospective study 双吻合器技术吻合在直肠和乙状结肠手术中的腔内冲洗:一项单机构的前瞻性研究。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-08-30 DOI: 10.1002/ags3.12851
Shinji Furuya, Kensuke Shiraishi, Hiroki Shimizu, Koichi Takiguchi, Makoto Sudo, Akaike Hidenori, Yoshihiko Kawaguchi, Hidetake Amemiya, Tetsuo Kondo, Daisuke Ichikawa

Aim

This study aimed to determine the necessity of intraluminal washout through cytological assessment to prevent implantation of exfoliated cancer cells (ECCs) in patients with rectal and sigmoid cancers.

Methods

We studied 140 patients with either sigmoid or rectal cancer who underwent anastomosis surgery using a double-stapling technique. An intraluminal washout sample was collected before and after irrigation with 1000, 1500, or 2000 mL of physiological saline or distilled water. Cytological assessments were conducted using the Papanicolaou classification system, where classes IV and V indicated positive cytological findings.

Results

Initially, 46.4% of the patients (65 out of 140) had positive ECCs. Patients with cancer cells had a significantly shorter distal free margin (DM) from the tumor (p < 0.001). The length of the DM was significantly associated with the tumor distance from the anal verge (p < 0.001). After irrigation with 2000 mL, ECCs were found in only 7.3% of patients. Logistic regression analysis showed that DM (≤50 mm) and tumor size (≥50 mm) were independent risk factors for positive ECCs after intraluminal washout, regardless of the type of irrigation solution used.

Conclusion

In patients with sigmoid colon cancer, adequate preoperative bowel preparation, a long DM, and a small tumor size, a 1000 mL intraluminal washout may be sufficient. By contrast, in patients with rectal cancer with a short DM and a large tumor size, a ≥2000 mL intraluminal washout is required. The different types of irrigation solution did not affect the ECCs. Large randomized controlled trials are required to confirm these results.

目的:本研究旨在通过细胞学评估确定腔内冲洗对预防直肠和乙状结肠癌患者脱落癌细胞(ECCs)着床的必要性。方法:我们研究了140例乙状结肠或直肠癌患者采用双吻合器技术进行吻合手术。在1000、1500或2000 mL生理盐水或蒸馏水冲洗前后收集腔内冲洗样本。使用Papanicolaou分类系统进行细胞学评估,其中IV级和V级表示细胞学结果阳性。结果:最初,46.4%的患者(140人中65人)有ECCs阳性。结论:对于乙状结肠直肠癌患者,术前充分的肠道准备、较长的游离缘和较小的肿瘤,1000 mL腔内冲洗可能就足够了。相比之下,对于DM短且肿瘤大的直肠癌患者,则需要≥2000 mL的腔内冲洗。不同灌洗液对ECCs无明显影响。需要大型随机对照试验来证实这些结果。
{"title":"Intraluminal washout in rectal and sigmoid colon cancer surgeries with double-stapling technique anastomosis: A single-institution prospective study","authors":"Shinji Furuya,&nbsp;Kensuke Shiraishi,&nbsp;Hiroki Shimizu,&nbsp;Koichi Takiguchi,&nbsp;Makoto Sudo,&nbsp;Akaike Hidenori,&nbsp;Yoshihiko Kawaguchi,&nbsp;Hidetake Amemiya,&nbsp;Tetsuo Kondo,&nbsp;Daisuke Ichikawa","doi":"10.1002/ags3.12851","DOIUrl":"10.1002/ags3.12851","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to determine the necessity of intraluminal washout through cytological assessment to prevent implantation of exfoliated cancer cells (ECCs) in patients with rectal and sigmoid cancers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We studied 140 patients with either sigmoid or rectal cancer who underwent anastomosis surgery using a double-stapling technique. An intraluminal washout sample was collected before and after irrigation with 1000, 1500, or 2000 mL of physiological saline or distilled water. Cytological assessments were conducted using the Papanicolaou classification system, where classes IV and V indicated positive cytological findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Initially, 46.4% of the patients (65 out of 140) had positive ECCs. Patients with cancer cells had a significantly shorter distal free margin (DM) from the tumor (<i>p</i> &lt; 0.001). The length of the DM was significantly associated with the tumor distance from the anal verge (<i>p</i> &lt; 0.001). After irrigation with 2000 mL, ECCs were found in only 7.3% of patients. Logistic regression analysis showed that DM (≤50 mm) and tumor size (≥50 mm) were independent risk factors for positive ECCs after intraluminal washout, regardless of the type of irrigation solution used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In patients with sigmoid colon cancer, adequate preoperative bowel preparation, a long DM, and a small tumor size, a 1000 mL intraluminal washout may be sufficient. By contrast, in patients with rectal cancer with a short DM and a large tumor size, a ≥2000 mL intraluminal washout is required. The different types of irrigation solution did not affect the ECCs. Large randomized controlled trials are required to confirm these results.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"137-144"},"PeriodicalIF":2.9,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term outcomes of robot-assisted versus conventional minimally invasive esophagectomy: A propensity score-matched study via a nationwide database 机器人辅助与传统微创食管切除术的短期结果:一项通过全国数据库进行的倾向评分匹配研究。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-08-29 DOI: 10.1002/ags3.12854
Tatsuto Nishigori, Hiraku Kumamaru, Kazutaka Obama, Koichi Suda, Shigeru Tsunoda, Yukie Yoda, Makoto Hikage, Susumu Shibasaki, Tsuyoshi Tanaka, Masanori Terashima, Yoshihiro Kakeji, Masafumi Inomata, Yuko Kitagawa, Hiroaki Miyata, Yoshiharu Sakai, Hirokazu Noshiro, Ichiro Uyama

Background

The advantages of robot-assisted minimally invasive esophagectomy (RA-MIE) over conventional minimally invasive esophagectomy (C-MIE) are unknown. This nationwide large-scale study aimed to compare surgical outcomes between RA-MIE and C-MIE using rigorous propensity score methods, including detailed covariates and relevant outcomes.

Methods

This Japanese nationwide retrospective cohort study included RA-MIE or C-MIE for esophageal malignant tumors performed between October 2018 and December 2019 and registered in the Japanese National Clinical Database. The primary outcome measure was postoperative complications classified as Clavien–Dindo Grade IIIa or higher. Propensity score matching was performed to create a balanced covariate distribution between the two groups.

Results

After propensity score matching, 1092 patients were selected. The RA-MIE group had a significantly longer operation time and greater blood loss than the C-MIE group (565 vs. 477 min and 120 vs. 90 mL). Furthermore, the R0 resection rate was lower in the RA-MIE group than in the C-MIE group (95.1% vs. 97.8%). The RA-MIE and C-MIE groups had no differences regarding overall complications ≥ Grade IIIa (22.0% vs. 20.3%, p = 0.52), 30-day mortality rates (0.4% vs. 0.5%), and operative mortality rates (0.7% vs. 0.7%). Deep SSI was less frequent (2.7% vs. 6.0%) and pulmonary embolism was more frequent (2.4% vs. 0.5%) in the RA-MIE group than in the C-MIE group.

Conclusions

In the initial phase of implementation, RA-MIE and C-MIE demonstrated comparable morbidity rates when performed by skilled board-certified endoscopic surgeons.

背景:机器人辅助微创食管切除术(RA-MIE)相对于传统微创食管切除术(C-MIE)的优势尚不清楚。这项全国性的大规模研究旨在使用严格的倾向评分方法比较RA-MIE和C-MIE的手术结果,包括详细的协变量和相关结果。方法:这项日本全国范围的回顾性队列研究包括2018年10月至2019年12月期间进行的食管恶性肿瘤RA-MIE或C-MIE,并在日本国家临床数据库中注册。主要结局指标是术后并发症,Clavien-Dindo分级为IIIa级或更高。进行倾向评分匹配以在两组之间创建平衡的协变量分布。结果:经倾向评分匹配后,入选1092例患者。RA-MIE组手术时间明显长于C-MIE组(565 vs. 477 min, 120 vs. 90 mL),出血量明显大于C-MIE组。此外,RA-MIE组的R0切除率低于C-MIE组(95.1%比97.8%)。RA-MIE组和C-MIE组在总并发症≥IIIa级(22.0% vs. 20.3%, p = 0.52)、30天死亡率(0.4% vs. 0.5%)和手术死亡率(0.7% vs. 0.7%)方面无差异。与C-MIE组相比,RA-MIE组的深度SSI发生率较低(2.7%对6.0%),肺栓塞发生率较高(2.4%对0.5%)。结论:在实施的初始阶段,RA-MIE和C-MIE在由熟练的委员会认证的内窥镜外科医生执行时显示出相当的发病率。
{"title":"Short-term outcomes of robot-assisted versus conventional minimally invasive esophagectomy: A propensity score-matched study via a nationwide database","authors":"Tatsuto Nishigori,&nbsp;Hiraku Kumamaru,&nbsp;Kazutaka Obama,&nbsp;Koichi Suda,&nbsp;Shigeru Tsunoda,&nbsp;Yukie Yoda,&nbsp;Makoto Hikage,&nbsp;Susumu Shibasaki,&nbsp;Tsuyoshi Tanaka,&nbsp;Masanori Terashima,&nbsp;Yoshihiro Kakeji,&nbsp;Masafumi Inomata,&nbsp;Yuko Kitagawa,&nbsp;Hiroaki Miyata,&nbsp;Yoshiharu Sakai,&nbsp;Hirokazu Noshiro,&nbsp;Ichiro Uyama","doi":"10.1002/ags3.12854","DOIUrl":"10.1002/ags3.12854","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The advantages of robot-assisted minimally invasive esophagectomy (RA-MIE) over conventional minimally invasive esophagectomy (C-MIE) are unknown. This nationwide large-scale study aimed to compare surgical outcomes between RA-MIE and C-MIE using rigorous propensity score methods, including detailed covariates and relevant outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This Japanese nationwide retrospective cohort study included RA-MIE or C-MIE for esophageal malignant tumors performed between October 2018 and December 2019 and registered in the Japanese National Clinical Database. The primary outcome measure was postoperative complications classified as Clavien–Dindo Grade IIIa or higher. Propensity score matching was performed to create a balanced covariate distribution between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After propensity score matching, 1092 patients were selected. The RA-MIE group had a significantly longer operation time and greater blood loss than the C-MIE group (565 vs. 477 min and 120 vs. 90 mL). Furthermore, the R0 resection rate was lower in the RA-MIE group than in the C-MIE group (95.1% vs. 97.8%). The RA-MIE and C-MIE groups had no differences regarding overall complications ≥ Grade IIIa (22.0% vs. 20.3%, <i>p</i> = 0.52), 30-day mortality rates (0.4% vs. 0.5%), and operative mortality rates (0.7% vs. 0.7%). Deep SSI was less frequent (2.7% vs. 6.0%) and pulmonary embolism was more frequent (2.4% vs. 0.5%) in the RA-MIE group than in the C-MIE group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In the initial phase of implementation, RA-MIE and C-MIE demonstrated comparable morbidity rates when performed by skilled board-certified endoscopic surgeons.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"109-118"},"PeriodicalIF":2.9,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of surgical outcomes and postoperative nutritional parameters between subtotal and proximal gastrectomy in patients with proximal early gastric cancer 早期近端胃癌近端切除术与胃大部切除术的手术效果及术后营养指标比较。
IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-08-28 DOI: 10.1002/ags3.12856
Wataru Soneda, Masanori Terashima, Yusuke Koseki, Kenichiro Furukawa, Keiichi Fujiya, Yutaka Tanizawa, Hiroya Takeuchi, Etsuro Bando

Aim

In this study, we evaluated the difference in short-term outcomes and postoperative nutritional status between subtotal gastrectomy (sTG) and proximal gastrectomy (PG) to determine the optimal surgical treatment for early gastric cancer in the upper third of the stomach.

Methods

Patients who underwent laparoscopic or robotic sTG or PG at the Shizuoka Cancer Center in Shizuoka between January 2014 and December 2020 were enrolled in this retrospective study. Patient characteristics, surgical outcomes, endoscopic findings, and postoperative nutritional changes, including blood tests, body weight, psoas muscle, and subcutaneous and visceral adipose tissue, were measured and compared between the two groups.

Results

A total of 110 patients were enrolled, including 42 in the sTG group and 68 in the PG group. Albumin and hemoglobin levels were comparable between the two groups. Changes in body weight and psoas mass index measured over 36 months postoperatively were favorable in the sTG group compared with the PG group (p = 0.005 and p = 0.002, respectively). There were no significant differences in subcutaneous or visceral adipose tissue between the two groups (p = 0.331 and 0.845, respectively).

Conclusion

sTG is the preferred function-preserving gastrectomy procedure for early gastric cancer in the upper third of the stomach because it is associated with less postoperative body weight loss and psoas mass index loss.

目的:在本研究中,我们评估胃大部切除术(sTG)和胃近端切除术(PG)的短期预后和术后营养状况的差异,以确定胃上三分之一早期胃癌的最佳手术治疗方法。方法:2014年1月至2020年12月在静冈市静冈市癌症中心接受腹腔镜或机器人sTG或PG治疗的患者纳入本回顾性研究。测量并比较两组患者的特征、手术结果、内窥镜检查结果和术后营养变化,包括血液检查、体重、腰肌、皮下和内脏脂肪组织。结果:共纳入110例患者,其中sTG组42例,PG组68例。两组之间的白蛋白和血红蛋白水平具有可比性。与PG组相比,sTG组术后36个月的体重和腰肌质量指数变化有利(p = 0.005和p = 0.002)。两组间皮下和内脏脂肪组织差异无统计学意义(p分别为0.331和0.845)。结论:sTG是胃上三分之一早期胃癌保留功能的首选胃切除术,其术后体重减轻和腰肌质量指数下降较少。
{"title":"Comparison of surgical outcomes and postoperative nutritional parameters between subtotal and proximal gastrectomy in patients with proximal early gastric cancer","authors":"Wataru Soneda,&nbsp;Masanori Terashima,&nbsp;Yusuke Koseki,&nbsp;Kenichiro Furukawa,&nbsp;Keiichi Fujiya,&nbsp;Yutaka Tanizawa,&nbsp;Hiroya Takeuchi,&nbsp;Etsuro Bando","doi":"10.1002/ags3.12856","DOIUrl":"10.1002/ags3.12856","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>In this study, we evaluated the difference in short-term outcomes and postoperative nutritional status between subtotal gastrectomy (sTG) and proximal gastrectomy (PG) to determine the optimal surgical treatment for early gastric cancer in the upper third of the stomach.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients who underwent laparoscopic or robotic sTG or PG at the Shizuoka Cancer Center in Shizuoka between January 2014 and December 2020 were enrolled in this retrospective study. Patient characteristics, surgical outcomes, endoscopic findings, and postoperative nutritional changes, including blood tests, body weight, psoas muscle, and subcutaneous and visceral adipose tissue, were measured and compared between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 110 patients were enrolled, including 42 in the sTG group and 68 in the PG group. Albumin and hemoglobin levels were comparable between the two groups. Changes in body weight and psoas mass index measured over 36 months postoperatively were favorable in the sTG group compared with the PG group (<i>p</i> = 0.005 and <i>p</i> = 0.002, respectively). There were no significant differences in subcutaneous or visceral adipose tissue between the two groups (<i>p</i> = 0.331 and 0.845, respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>sTG is the preferred function-preserving gastrectomy procedure for early gastric cancer in the upper third of the stomach because it is associated with less postoperative body weight loss and psoas mass index loss.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8030,"journal":{"name":"Annals of Gastroenterological Surgery","volume":"9 1","pages":"89-97"},"PeriodicalIF":2.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annals of Gastroenterological Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1