Pub Date : 2014-01-01DOI: 10.1016/B978-0-12-800167-7.00017-1
R. Reich, C. Supuran, E. Breuer
{"title":"Chapter Seventeen - Tumor Microenvironment as Target in Cancer Therapy","authors":"R. Reich, C. Supuran, E. Breuer","doi":"10.1016/B978-0-12-800167-7.00017-1","DOIUrl":"https://doi.org/10.1016/B978-0-12-800167-7.00017-1","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-800167-7.00017-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54159089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.1016/B978-0-12-800167-7.00004-3
P. Galatsis, Jaclyn L Henderson, B. L. Kormos, W. Hirst
{"title":"Chapter Four - Development of LRRK2 Kinase Inhibitors for Parkinson's Disease","authors":"P. Galatsis, Jaclyn L Henderson, B. L. Kormos, W. Hirst","doi":"10.1016/B978-0-12-800167-7.00004-3","DOIUrl":"https://doi.org/10.1016/B978-0-12-800167-7.00004-3","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-800167-7.00004-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54158982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00006-5
S. Kuduk, C. Winrow, P. Coleman
{"title":"Chapter Six – Orexin Receptor Antagonists in Development for Insomnia and CNS Disorders","authors":"S. Kuduk, C. Winrow, P. Coleman","doi":"10.1016/B978-0-12-417150-3.00006-5","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00006-5","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00006-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54121753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00007-7
Sarah Chajkowski Scarry, J. Rimoldi
{"title":"Chapter Seven - Discovery and Development of Prolylcarboxypeptidase Inhibitors for Cardiometabolic Disorders","authors":"Sarah Chajkowski Scarry, J. Rimoldi","doi":"10.1016/B978-0-12-417150-3.00007-7","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00007-7","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00007-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54121790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00018-1
K. Hevener, Shuyi Cao, Tian Zhu, P. Su, S. Mehboob, Michael E. Johnson
{"title":"Special Challenges to the Rational Design of Antibacterial Agents","authors":"K. Hevener, Shuyi Cao, Tian Zhu, P. Su, S. Mehboob, Michael E. Johnson","doi":"10.1016/B978-0-12-417150-3.00018-1","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00018-1","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00018-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54122169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00012-0
T. Dhar, Qihong Zhao, D. Markby
{"title":"Chapter Twelve - Targeting the Nuclear Hormone Receptor RORγt for the Treatment of Autoimmune and Inflammatory Disorders","authors":"T. Dhar, Qihong Zhao, D. Markby","doi":"10.1016/B978-0-12-417150-3.00012-0","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00012-0","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00012-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54121954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00019-3
Rohan E. J. Beckwith, R. Jain
{"title":"Recent Advances in Small Molecule Target Identification Methods","authors":"Rohan E. J. Beckwith, R. Jain","doi":"10.1016/B978-0-12-417150-3.00019-3","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00019-3","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00019-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54122212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00001-6
A. Ganguly
{"title":"Challenges in Drug Discovery at Schering–Plough Research Institute","authors":"A. Ganguly","doi":"10.1016/B978-0-12-417150-3.00001-6","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00001-6","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00001-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54121632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00008-9
C. Casagrande, D. Arosio, C. Kusmic, L. Manzoni, L. Menichetti, A. L'Abbate
{"title":"Chapter Eight - Molecular Targeting of Imaging and Drug Delivery Probes in Atherosclerosis","authors":"C. Casagrande, D. Arosio, C. Kusmic, L. Manzoni, L. Menichetti, A. L'Abbate","doi":"10.1016/B978-0-12-417150-3.00008-9","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00008-9","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00008-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54121819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1016/B978-0-12-417150-3.00014-4
D. Wustrow, Han-Jie Zhou, M. Rolfe
{"title":"Chapter Fourteen - Inhibition of Ubiquitin Proteasome System Enzymes for Anticancer Therapy","authors":"D. Wustrow, Han-Jie Zhou, M. Rolfe","doi":"10.1016/B978-0-12-417150-3.00014-4","DOIUrl":"https://doi.org/10.1016/B978-0-12-417150-3.00014-4","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/B978-0-12-417150-3.00014-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54122020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}