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Reflections on valve-sparing operations utilizing straight tube versus Valsalva grafts. 直管与Valsalva移植物保瓣手术的比较。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-11
Hans-Hinrich Sievers, Michael Scharfschwerdt
muscles (3). Furthermore, the downsized root diameters potentially lead to leaflet redundancy and leaflet folds often requiring surgical adaptation. How much correction of the leaflets in a non-distensible prosthesis is necessary? Together these factors prevent the leaflets from completely aligning and adhering to the wall but do not prevent the intermittent wall contact of the leaflets that was reported as a constant echocardiographic finding after the David operation with a straight tube (4), but not when a sinus was present (5). Magnetic resonance imaging confirmed these results and additionally found malrotated vortices behind the leaflets in a straight tube with unknown sequelae (3). In our experiments also
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引用次数: 0
Outcomes of aortic root replacement in patients with Marfan syndrome: the role of valve-sparing and valve-replacing approaches. 马凡氏综合征患者主动脉根置换术的结果:保留瓣膜和瓣膜置换术的作用。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-0085
Joseph S Coselli, Irina V Volguina, Lynna Nguyen, Susan Y Green, Scott A LeMaire, Marc R Moon
Background Marfan syndrome (MFS) is a heritable thoracic aortic disease with pervasive cardiovascular effects, including commonly, a dilated aortic root. Traditionally, the root is replaced using a mechanical composite valve graft (CVG); however, this valve-replacing (VR) approach necessitates a lifelong regimen of anticoagulation with a potential for late bleeding complications. In time, valve-sparing (VS) approaches were developed. Today, several options for aortic root replacement (ARR) exist; each has advantages and disadvantages that helps inform choice. The Aortic Valve Operative Outcomes in Marfan Patients (AVOMP) is a multi-center international registry to analyze clinical outcomes of ARR in MFS patients using either VR or VS techniques to better elucidate choice. We summarize outcomes of AVOMP and present our own experience. Methods We performed 223 consecutive elective ARR [1991–2023] in patients with MFS; 15 such repairs were included in AVOMP. Repairs included 113 (51%) using a mechanical CVG, 62 (28%) using a VS approach, and 48 (22%) using a bioprosthetic root. Many patients underwent aortic arch repair (30% to 54% by type). Results The median patient age was 38 [29–52] years. In comparing VS and VR groups, patients were similar in age and rates of major comorbidities and symptoms. Patients with VR repair had a more complex aortic history. The rate of redo sternotomy was 24% (n=54). Operative death was uncommon [4% overall (10/223); ranging from 2% to 8% by type], and stroke was rare [1/223 (<1%)]. Late survival and reoperation differed by operative approach; survival was improved in patients who underwent VS repair. Conclusions We found that repair in patients with MFS undergoing ARR resulted in low operative risk. Our late results were similar to those of AVOMP in that patients undergoing VS repair tended to experience greater rates of valvular-structural deterioration, although this did not appear to impact survival.
背景:马凡氏综合征(MFS)是一种遗传性胸主动脉疾病,具有普遍的心血管影响,通常包括主动脉根扩张。传统上,使用机械复合瓣膜移植物(CVG)代替根;然而,这种瓣膜置换(VR)方法需要终身抗凝治疗,并有可能出现晚期出血并发症。随着时间的推移,阀门保护(VS)方法被开发出来。目前,存在几种主动脉根部置换(ARR)的选择;每一种都有优点和缺点,有助于做出选择。马凡患者主动脉瓣手术结局(AVOMP)是一项多中心国际注册研究,旨在使用VR或VS技术分析MFS患者ARR的临床结果,以更好地阐明选择。我们总结了AVOMP的结果,并提出了自己的经验。方法:我们对223例MFS患者进行了连续选择性ARR [1991-2023];在AVOMP中包括15次这样的修理。修复包括113例(51%)使用机械CVG, 62例(28%)使用VS方法,48例(22%)使用生物修复根。许多患者接受了主动脉弓修复(按类型划分为30% - 54%)。结果:患者中位年龄38岁[29-52]岁。在VS组和VR组的比较中,患者的年龄和主要合并症和症状的发生率相似。VR修复患者的主动脉病史更为复杂。胸骨切开术复发率为24% (n=54)。手术死亡不常见[总体为4% (10/223);[1/223]结论:我们发现,接受ARR的MFS患者的修复导致较低的手术风险。我们的最新结果与AVOMP相似,接受VS修复的患者往往经历更大的瓣膜结构恶化率,尽管这似乎不影响生存。
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引用次数: 0
Valve-sparing operations after Ross procedure: a single-center experience. 罗斯手术后保留瓣膜手术:单中心经验。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-0100
Jama Jahanyar, Bardia Arabkhani, Luca Zanella, Laurent de Kerchove, Peter I Tsai, Gaby Aphram, Stefano Mastrobuoni, Gebrine El Khoury

Background: The Ross procedure has demonstrated excellent long-term results, with restoration of life-expectancy in patients with severe aortic valve dysfunction. However, reintervention after Ross can occur, and herein we describe our center's experience with redo surgery after previous Ross procedures.

Methods: We searched our prospective database for aortic valve-repair and recruited all adult (≥18 years) patients who have undergone valve-sparing root replacements (VSRRs) and/or aortic valve-repair after Ross procedure between July 2001 and July 2022. Univariable logistic regression analysis was performed to identify variables affecting early mortality. Survival, freedom-from-valve-reintervention and freedom-from-aortic regurgitation (AR) grade ≥3 were analyzed with the Kaplan-Meier method.

Results: A total of 63 patients were recruited for this study. Indication for reoperation after Ross was aortic aneurysm without AR in 17 (27%), aortic aneurysm with AR in 27 (43%), and isolated AR in 19 (30%) patients. Median follow-up time was 7.82 years. The majority of patients (76%) had undergone the free root technique during their index Ross operation. Cumulative survival, after redo surgery following Ross, was 98.4% [95% confidence interval (CI): 89.3-99.8%] at 1 year, 96.3% (95% CI: 88.2-98.3%) at 5 years, and 92.4% (95% CI: 87.1-98.0%) at 10 years. Freedom-from-reoperation on the aortic valve at 1 year was 98.4% (95% CI: 97.0-99.8%), at 5 years was 96.7% (95% CI: 87.6-99.0%), and 79.7% (95% CI: 71.1-88.3%) at 10 years.

Conclusions: Long-term survival after redo surgery following the Ross operation is excellent. The data support our aggressive valve-sparing approach after Ross.

背景:Ross手术已经证明了良好的长期效果,可以恢复严重主动脉瓣功能障碍患者的预期寿命。然而,罗斯手术后的再干预也可能发生,在此我们描述本中心在之前的罗斯手术后再做手术的经验。方法:我们检索了主动脉瓣修复的前瞻性数据库,并招募了2001年7月至2022年7月期间在Ross手术后接受保留瓣膜根置换(VSRRs)和/或主动脉瓣修复的所有成人(≥18岁)患者。采用单变量logistic回归分析确定影响早期死亡率的变量。生存率、无瓣膜再干预和无主动脉反流(AR)≥3级采用Kaplan-Meier法进行分析。结果:本研究共招募了63例患者。Ross术后再手术指征为无AR主动脉瘤17例(27%),合并AR主动脉瘤27例(43%),孤立AR 19例(30%)。中位随访时间为7.82年。大多数患者(76%)在其指数Ross手术中进行了游离根技术。Ross术后重做手术后,1年的累积生存率为98.4%[95%可信区间(CI): 89.3-99.8%], 5年的累积生存率为96.3% (95% CI: 88.2-98.3%), 10年的累积生存率为92.4% (95% CI: 88.1 -98.0%)。1年时主动脉瓣再手术自由率为98.4% (95% CI: 97.0-99.8%), 5年时为96.7% (95% CI: 87.6-99.0%), 10年时为79.7% (95% CI: 71.1-88.3%)。结论:Ross手术后重做术后长期生存率高。罗斯手术后的数据支持我们积极保留瓣膜的方法。
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引用次数: 0
Aortic root remodeling. 主动脉根部重塑。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-12
Christian Giebels, Tristan Ehrlich, Hans-Joachim Schäfers

Aortic root remodeling was originally designed in the late 1980s to treat patients with tricuspid aortic valves (TAVs), aortic regurgitation (AR), and root aneurysm to normalize root dimensions. The late results showed a relevant proportion of patients who required reoperation for recurrent AR. Later observations revealed that cusp prolapse is frequently present after correction of root dilatation. We showed that such prolapse could be detected by measuring effective height (eH) and corrected by concomitant cusp repair. In the past 13 years, we have added a suture annuloplasty to improve aortic valve function further. The operation starts with ascertaining adequate cusp size by measuring geometric cusp height. The dilated aortic wall is resected, and a Dacron graft is tailored to create three tongues. These tongues are sutured to the cusp insertion lines. Starting the suture in the nadir allows for easy extension of tongue length to avoid commissural height restriction. A suture annuloplasty is added at nadir level and tied around a Hegar dilator to normalize annular diameter. The valve is assessed visually and by measuring eH. Cusp prolapse (eH <9 mm) is frequent and corrected by free margin plication until all free margins are at equal level and eH is 9 mm. We have employed root remodeling in more than 710 instances of root aneurysm and TAVs. Mean myocardial ischemic time has been 65±13 minutes for isolated remodeling, operative mortality has been 1.5% for elective procedures. With suture annuloplasty, 10-year freedom from reoperation is 95%, even without suture annuloplasty 20-year freedom from reoperation is 85%. In our experience, root remodeling has been a valid form of valve-preserving surgery with low morbidity and mortality and excellent long-term results.

主动脉根部重塑最初是在20世纪80年代后期设计的,用于治疗三尖瓣主动脉瓣(TAVs)、主动脉反流(AR)和根部动脉瘤患者,以使根部尺寸正常化。后期的结果显示,复发性AR患者需要再次手术的比例相关。后期的观察显示,根尖扩张矫正后经常出现根尖脱垂。我们发现这种脱垂可以通过测量有效高度(eH)来检测,并通过伴随的尖端修复来纠正。在过去的13年里,我们增加了缝合环成形术来进一步改善主动脉瓣功能。该操作首先通过测量几何尖头高度来确定适当的尖头大小。扩张的主动脉壁被切除,一个涤纶移植物被定制成三个舌头。这些舌被缝合在尖插入线上。从最低点开始缝合可以很容易地延长舌长,以避免关节高度限制。在最低点添加缝合环成形术,并将其绑在Hegar扩张器周围以使环直径正常化。通过目视和测量eH来评估阀门。尖脱垂(eH
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引用次数: 0
From valve-sparing aortic root replacement to aortic root reconstruction: the importance of aortic valve repair. 从保留瓣膜的主动脉根部置换到主动脉根部重建:主动脉瓣修复的重要性。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-20
Charles Laurin, Elbert Williams, Ismail El-Hamamsy
As the term aptly describes, valve-sparing aortic root replacement (VSRR) was initially designed to address patients with primary aortic root pathology and very little to no aortic valve (AV) dysfunction. If present, any degree of aortic insufficiency (AI) was secondary to dilatation of the aortic annulus and/or the sinotubular junction (STJ), in association with the aneurysm of the sinuses of Valsalva. Restoring the anatomy of the aortic root components would thus restore AV function. However, it is important to remember that the functional aortic root is composed of four inter-related parts: the virtual basal ring, the STJ, the sinuses of Valsalva, as well as the AV cusps. In patients with aneurysms of the sinuses of Valsalva, there are inevitably compensatory or pathological changes in the structure of the AV cusps in response to the changes in aortic root dimensions, ranging from elongation to stress fenestrations, especially in areas of high stress near the commissures. Thus, it became evident that restoring the dimension of the annulus and STJ without any attention to the last component parts of the aortic root could result in early failure of a VSRR, including in patients with seemingly normal AV function preoperatively (1). This commenced the era of AV repair. It was soon recognized that residual or induced prolapse of the AV cusps after completion of the VSRR was associated with recurrence of AI and need for reintervention (1). Indeed, as the aortic root dilates and becomes aneurysmal, AV cusps adapt to different extents, which explains the wide variations in severity of AI in patients with similarly sized aortic root aneurysms. Aortic cusps elongate in both their radial and circumferential axes through active, living processes (2). Failure to recognize this at the time of VSSR, and instead restoring to normal AV cusp configuration (effective height, coaptation length and symmetry), as described by the pioneering work of the Brussels and Homburg teams, will lead to failure of the seemingly most straight-forward VSRR procedures for aortic root aneurysms in patients with tricuspid aortic valve (TAV) (3-5). As the applications of VSRR have expanded, a wider group of patients should be considered for these procedures, namely patients with bicuspid aortic valves (BAV) or those with TAVs and eccentric jets of AR. In both instances, there is invariably some element of abnormal cusp structure, typically in the form of cusp prolapse. This is true in the majority of patients with regurgitant BAVs. As has been known in the mitral world for many years, failure to correct cusp prolapse at the time of surgery will negatively impact the durability of the operation. Concepts of BAV preservation and repair are increasingly well understood and standardized (6,7). There is no doubt that most VSRR operations today for patients with BAV and significant AI should involve some element of cusp repair, ranging from raphe release to increase geometric height and
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引用次数: 0
Severe aortic valve insufficiency with a 'normal' appearing aortic root: reimplantation (David) procedure. 严重主动脉瓣功能不全,主动脉根部看起来“正常”:重植术。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-14
Munir Boodhwani, Ming Hao Guo, Adam Dryden, David Glineur
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引用次数: 0
Mini-access David Procedure with endoscopic assessment of aortic valve competency: the "Snorkelling" technique. 内窥镜评估主动脉瓣功能的迷你通道大卫程序:“浮潜”技术。
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-31 DOI: 10.21037/acs-2023-avs2-0101
Victoria Cook, Mathew Doyle, Tristan D Yan
A 58-year-old man was referred with an incidental finding of an aortic root aneurysm. He had no significant medical history. Computed tomography (CT) aortogram demonstrated an isolated aortic root aneurysm (aortic annulus 28 mm, aortic root 53 mm, sinotubular junction 53 mm). Transthoracic echocardiogram demonstrated a dilated aortic root and a tri-leaflet aortic valve with mild aortic regurgitation (AR). The left ventricular (LV) ejection fraction was preserved. Cardiac catheterization demonstrated mild non-obstructive coronary artery disease only. Given the patients’ age, structurally normal-appearing valve and borderline annular dimension, minimally-invasive aortic valve reimplantation was planned. The minimally invasive approach was based on surgeon and patient preference.
{"title":"Mini-access David Procedure with endoscopic assessment of aortic valve competency: the \"Snorkelling\" technique.","authors":"Victoria Cook,&nbsp;Mathew Doyle,&nbsp;Tristan D Yan","doi":"10.21037/acs-2023-avs2-0101","DOIUrl":"https://doi.org/10.21037/acs-2023-avs2-0101","url":null,"abstract":"A 58-year-old man was referred with an incidental finding of an aortic root aneurysm. He had no significant medical history. Computed tomography (CT) aortogram demonstrated an isolated aortic root aneurysm (aortic annulus 28 mm, aortic root 53 mm, sinotubular junction 53 mm). Transthoracic echocardiogram demonstrated a dilated aortic root and a tri-leaflet aortic valve with mild aortic regurgitation (AR). The left ventricular (LV) ejection fraction was preserved. Cardiac catheterization demonstrated mild non-obstructive coronary artery disease only. Given the patients’ age, structurally normal-appearing valve and borderline annular dimension, minimally-invasive aortic valve reimplantation was planned. The minimally invasive approach was based on surgeon and patient preference.","PeriodicalId":8067,"journal":{"name":"Annals of cardiothoracic surgery","volume":"12 4","pages":"389-391"},"PeriodicalIF":3.1,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/9e/acs-12-04-389.PMC10405336.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9963098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuromonitoring for descending thoracic and thoracoabdominal aortic aneurysm repair 神经监测在胸腹降主动脉瘤修复中的应用
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-07-27 DOI: 10.21037/asvide.2023.151
A. Tanaka, H. Nguyen, Holly N. Smith, A. Estrera
A forty-four-year-old female presented with an extent II thoracoabdominal aortic aneurysm (TAAA) and lower back pain. Computed tomography demonstrated contained rupture of the 10 cm infrarenal abdominal aorta. The proximal descending aorta (DTA) was 5.5 cm in diameter but the aortic segment T8 to T12 was 3 cm in diameter. Thus, staged repair of the TAAA was planned. The patient successfully underwent first-stage, extent IV TAAA repair, which includes replacement of the aorta from T12 proximally to right iliac and left common femoral distally with bypass to the visceral/renal arteries. There were no motor evoked potentials (MEPs) or somatosensory evoked potentials (SSEPs) changes. All the patent lumbar arteries were ligated. Her postoperative course was uneventful. After ten days of recovery, the patient was taken back to the operating room for the second stage, completion of the extent II TAAA repair.
一位44岁的女性出现II度胸腹主动脉瘤(TAAA)和下背痛。计算机断层扫描显示肾下腹主动脉10厘米破裂。近端降主动脉(DTA)的直径为5.5cm,但主动脉段T8至T12的直径为3cm。因此,计划分阶段修复TAAA。患者成功地接受了第一阶段IV度TAAA修复,其中包括从T12近端到右髂和左股总远端的主动脉置换,以及内脏/肾动脉的旁路。无运动诱发电位(MEP)或体感诱发电位(SSEP)变化。结扎所有未闭的腰动脉。她的术后进展顺利。康复十天后,患者被带回手术室进行第二阶段,完成II度TAAA修复。
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引用次数: 0
Severe aortic valve insufficiency with a ‘normal’ appearing aortic root: reimplantation (David) procedure 严重主动脉瓣功能不全,主动脉根部看起来“正常”:重植术
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-06-19 DOI: 10.21037/asvide.2023.116
M. Boodhwani, Ming Guo, A. Dryden, D. Glineur
sutures were placed. Valve inspection revealed a trileaflet aortic valve with thickening of the free margins of all three cusps. The cusps were mobile with no obvious fenestrations or calcification. Inspection of the left cusp suggested some degree of prolapse, with bending of the cusp and the presence of a fibrous band. Inspection of the aortic root revealed normal quality tissue, except in the area of the VAJ under the right coronary cusp. The geometric heights of the left, right, and non-coronary cusps measured 18, 21, and 20 mm, respectively. A 6-0 prolene suture was used to retract the ventricular surface of the cusps and the thickened portion of the leaflets was shaved off with a #11 blade to improve cusp mobility. External dissection of the aortic root was performed to enable access to the VAJ at which level the annuloplasty needs be performed. We started with the non-coronary sinus, dissecting down to the level of leaflet insertion. The sinus was resected, leaving behind a 5–7 mm rim of aortic tissue. A similar dissection was performed after harvesting the right coronary button, followed by the left coronary button. The pulmonary artery and right ventricle were detached from the aortic root. A deep dissection (3) was performed by going through the aorto-pulmonary ligament, which is the white fibrous tissue followed by yellowish fat tissue underneath and then into
缝合。瓣膜检查发现一个三瓣主动脉瓣,三个瓣尖的自由边缘都增厚。牙尖可移动,无明显开窗或钙化。左鼻尖检查显示有一定程度的脱垂,伴有鼻尖弯曲和纤维带的存在。主动脉根部检查显示,除右冠状动脉尖下的VAJ区域外,其他组织质量正常。左、右、非冠状动脉尖的几何高度分别为18、21、20毫米。使用6-0 prolene缝线收缩脑尖的心室表面,用11号刀片刮去小叶的增厚部分,以改善脑尖的活动性。对主动脉根部进行外部剥离,以便进入VAJ,在VAJ处需要进行环成形术。我们从非冠状动脉窦开始,解剖到小叶插入的水平。窦被切除,留下一个5-7毫米的主动脉组织边缘。在获取右侧冠状动脉按钮后进行类似的剥离,然后是左侧冠状动脉按钮。肺动脉和右心室与主动脉根部分离。通过主动脉-肺韧带进行深度剥离(3),这是白色的纤维组织,下面是淡黄色的脂肪组织,然后进入
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引用次数: 0
Open repair of a thoracoabdominal aortic aneurysm using hypothermic cardiopulmonary bypass and circulatory arrest 应用低温体外循环和停循环开放性修复胸腹主动脉瘤
IF 3.1 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-06-12 DOI: 10.21037/asvide.2023.114
N. Kouchoukos
A 78-year-old female presented with recent onset of interscapular chest pain. She was a smoker and had previously undergone coronary artery stenting. Left ventricular function was normal. A computed tomography (CT) angiogram showed aneurysmal degeneration of the distal descending thoracic and the entire abdominal aorta. There were high-grade stenoses at the origins of the celiac, superior mesenteric, and both renal arteries. This was classified as a Crawford extent III thoracoabdominal aortic aneurysm.
一位78岁的女性最近出现了肩胛间胸痛。她是一名吸烟者,之前曾接受过冠状动脉支架植入术。左心室功能正常。计算机断层扫描(CT)血管造影显示远端降胸主动脉和整个腹主动脉的动脉瘤样变性。腹腔、肠系膜上动脉和两个肾动脉的起源处有高度狭窄。这被归类为克劳福德III度胸腹主动脉瘤。
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引用次数: 0
期刊
Annals of cardiothoracic surgery
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