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Modeling the Agility head of the VersaHD accelerator and its beam profile by Geant4: Logfile-based geometry implementation 通过Geant4建模VersaHD加速器的敏捷头及其光束轮廓:基于logfile的几何实现
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-07 DOI: 10.1016/j.apradiso.2026.112555
Le Van Tinh , Phan Viet Cuong , Nguyen Van Kien , Chau Ngoc Anh Minh , Pham Duc Khue , Nguyễn Thanh Bình , Le Tuan Anh
The motivation of this work is to develop a comprehensive Monte Carlo simulation code based on the Geant4 toolkit for modeling the Elekta Agility head of the VersaHD linear accelerator. This effort aims to support the treatment planning and medical research activities at Vietnam National Cancer Hospital. The code implementation allows reading the logfiles recorded during treatment and recalculating the actual patient dose distribution, which can be applied for patient-specific quality assurance (PSQA). The simulation model was validated through comparisons with experimental measurements, including percentage depth dose (PDD) and lateral dose profiles acquired using a water phantom and an ionization chamber dosimeter. A gamma index analysis demonstrated good agreement between simulation and measurement with the 3%/3 mm acceptance criteria for lateral dose profiles. Similarly, the PDD analysis with the 2%/2 mm acceptance criteria yielded equally satisfactory results.
这项工作的动机是基于Geant4工具包开发一个全面的蒙特卡罗仿真代码,用于对VersaHD线性加速器的Elekta Agility头进行建模。这项工作旨在支持越南国立癌症医院的治疗计划和医学研究活动。代码实现允许读取治疗期间记录的日志文件并重新计算实际患者剂量分布,可用于患者特定质量保证(PSQA)。仿真模型通过与实验测量值的比较进行了验证,包括百分比深度剂量(PDD)和使用水幻影和电离室剂量计获得的侧向剂量分布。伽马指数分析表明,模拟和测量之间的良好一致性与3%/3 mm接受标准的侧向剂量剖面。同样,采用2%/2 mm接受标准的PDD分析也产生了同样令人满意的结果。
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引用次数: 0
Systematic investigation of the relationship between neutron radiative capture cross sections and fundamental nuclear properties in isotopes of Ca, Ti, Zn, Ge, Se, and Kr at 30 and 1420 keV 30和1420 keV下Ca, Ti, Zn, Ge, Se和Kr同位素中子辐射俘获截面与基本核性质关系的系统研究。
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-03 DOI: 10.1016/j.apradiso.2026.112538
Mohammad Alshaikh , Abdullah Rastanawi , Khaled Alnssar , Suleiman Dibo
In this work, Maxwellian-averaged neutron capture cross sections (MACS) for stable isotopes of Ca, Ti, Zn, Ge, Se, and Kr at 30 and 1420 keV are systematically investigated to establish predictive links with fundamental nuclear-structure properties. A fully model-independent methodology is applied through graphical trend analysis across isotopic chains, revealing robust correlations between σn,γ and neutron separation energy (Sn), binding energy per nucleon (B/A), and quadrupole deformation (β2). The results demonstrate that σn,γ increases with Sn and β2 while showing a clear inverse dependence on B/A. On this basis, a compact empirical expression is proposed that unifies key structural and reaction parameters, enabling reliable reproduction of evaluated data and extending predictive capability for isotopes lacking measurements.
在这项工作中,系统地研究了Ca, Ti, Zn, Ge, Se和Kr稳定同位素在30和1420 keV下的麦克斯韦平均中子俘获截面(MACS),以建立与基本核结构性质的预测联系。通过对同位素链的图形趋势分析,采用了完全独立于模型的方法,揭示了σn、γ与中子分离能(Sn)、每核子结合能(B/A)和四极变形(β2)之间的鲁棒相关性。结果表明:σn、γ随Sn和β2的增大而增大,与B/ a呈明显的反比关系;在此基础上,提出了一个紧凑的经验表达式,统一了关键的结构和反应参数,使评估数据能够可靠地再现,并扩展了缺乏测量的同位素的预测能力。
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引用次数: 0
Phase error reduction in ILSF undulators using a genetic algorithm for sorting the magnetic blocks 利用遗传算法对磁块进行分类,降低ILSF波动器的相位误差。
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-02 DOI: 10.1016/j.apradiso.2026.112534
Karam Mohammadpour , Farhad Saeidi , Mansour Hadad , Naser Vosoughi
The insertion device for the Iranian light source facility (ILSF), a 3 GeV third-generation light source, is in the design and construction phase. Insertion devices incorporate up to several thousand magnetic blocks to generate a sinusoidal magnetic field. The primary sources of limitations in the spectral flux and brilliance are the different remanence magnetizations for each magnet block, which are unavoidable. The magnetic field error affects the phase radiation and path of the electron, as well as other issues. The phase error directly affects the relative intensity of the radiation; thus, the intensity decreases with an increase in the phase error. These magnets must be measured and appropriately sorted to minimize phase errors. This study used genetic algorithms on an ILSF's pure permanent magnet undulator as a sorting technique to minimize phase error. The genetic algorithm was implemented using the Wolfram programming language. The optimal magnetic sorting achieved through a genetic algorithm reduces the phase error to 8.78°, which is an 82.9% decrease compared to a random magnetic block setup (51.41°). As a result, the relative intensity increases to 0.98, representing a 104% rise over the random arrangement (0.48), and the electron beam deviation from the undulator axis drops by 90%, from 81.66 μm to 7.93 μm.
伊朗光源设施(ILSF)的插入装置是一个3 GeV第三代光源,目前正处于设计和建造阶段。插入装置包含多达数千个磁块以产生正弦磁场。限制光谱通量和亮度的主要原因是每个磁块的剩余磁化强度不同,这是不可避免的。磁场误差影响电子的相位辐射和路径等问题。相位误差直接影响辐射的相对强度;因此,强度随相位误差的增大而减小。这些磁铁必须测量和适当分类,以尽量减少相位误差。本研究采用遗传算法对ILSF的纯永磁体波动器进行排序,以减小相位误差。遗传算法采用Wolfram编程语言实现。通过遗传算法实现的最优磁分选将相位误差降低到8.78°,与随机磁块设置(51.41°)相比降低了82.9%。结果表明,相对强度增加到0.98,比随机排列(0.48)提高了104%,电子束与波动轴的偏差从81.66 μm减小到7.93 μm,减小了90%。
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引用次数: 0
Tailoring optical and radiation shielding properties of manganese lead borate glasses via silver iodide modification 通过碘化银改性来剪裁锰铅硼酸盐玻璃的光学和辐射屏蔽性能
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-07 DOI: 10.1016/j.apradiso.2026.112530
Islam M. Nabil , Ashraf A. Abul-Magd , Hesham M.H. Zakaly , Sameh A. Elhameed , Nancy N. Elewa , Shaaban M. Shaaban , Islam N. Fathy
This study investigates the structural and physical modifications induced by the incorporation of silver iodide (AgI) into a borate glass matrix. A glass series with the general formula ((75-x) B2O3 + 20PbO + 5MnO2 + xAgI), where 0 ≤ x ≤ 2.0 mol% in increments of 0.5 mol%, was synthesized. The glass samples were examined using Fourier transform infrared (FT-IR), optical spectroscopy, density measurements, and other analytical tools. Furthermore, the radiation shielding proficiency of the investigated glass system was evaluated through Monte Carlo simulations and Phy-X software, focusing on parameters such as the linear attenuation coefficient (μ), mass attenuation coefficient (μm), half value layer (HV), etc. Experimental results revealed that increasing the AgI content from 0 to 2.0 mol% led to a 7.7% linear increase in density, rising from 3.12 to 3.36 g/cm3, while the molar volume decreased from 32.4 to 31.1 cm3/mol. FT-IR analysis indicated that AgI acts as a lattice modifier, facilitating the conversion of BO4 units to BO3 units and subsequently increasing the concentration of non-bridging oxygens (NBOs). These structural changes, alongside heightened internal lattice disorder, resulted in a reduction of 3.04% of the optical band gap from 2.96 to 2.87 eV. Optical spectra further demonstrated that Ag+ ions influence the coordination of manganese, favoring the transition of Mn2+ ions from tetrahedral to octahedral sites. Shielding analysis confirmed that the linear attenuation coefficient follows the order: BPbMnAg0.0 < BPbMnAg0.5 < BPbMnAg1.0 < BPbMnAg1.5 < BPbMnAg2.0. Additionally, calculated effective removal cross-sections indicated that increasing AgI concentrations significantly enhance fast neutron removal capacity. These findings suggest that AgI-doped manganese lead borate glasses are highly effective candidates for advanced photon and neutron shielding applications.
本研究探讨了碘化银(AgI)掺入硼酸盐玻璃基体所引起的结构和物理修饰。合成了通式为((75-x) B2O3 + 20PbO + 5MnO2 + xAgI)的玻璃系列,其中0≤x≤2.0 mol%,增量为0.5 mol%。使用傅里叶变换红外(FT-IR)、光谱学、密度测量和其他分析工具对玻璃样品进行了检测。此外,通过Monte Carlo模拟和Phy-X软件对所研究的玻璃系统的辐射屏蔽能力进行了评估,重点关注线性衰减系数(μ)、质量衰减系数(μm)、半值层(HV)等参数。实验结果表明,AgI含量从0增加到2.0 mol%,密度线性增加7.7%,从3.12上升到3.36 g/cm3,而摩尔体积从32.4下降到31.1 cm3/mol。FT-IR分析表明,AgI作为晶格修饰剂,促进BO4单元向BO3单元的转化,从而增加非桥接氧(NBOs)的浓度。这些结构变化,加上内部晶格无序性的增强,导致光学带隙从2.96 eV减小到2.87 eV,减小了3.04%。光谱进一步表明Ag+离子影响锰的配位,有利于Mn2+离子从四面体位向八面体位过渡。屏蔽分析证实线性衰减系数顺序为:BPbMnAg0.0 <; BPbMnAg0.5 <; BPbMnAg1.0 <; BPbMnAg1.5 <; BPbMnAg2.0。此外,计算出的有效去除截面表明,增加AgI浓度显著提高了快中子去除能力。这些发现表明,掺杂agi的锰铅硼酸盐玻璃是先进光子和中子屏蔽应用的高效候选者。
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引用次数: 0
Indoor radon gas measurements and its cancer risk using radon-scout detector 用氡探测仪测量室内氡气及其致癌风险。
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-02 DOI: 10.1016/j.apradiso.2026.112537
Nada Farhan Kadhim , Yasser Ayad Kadhim , Hala Adnan Ahmed , Mohammed jawad Kadhim , Hyam Nazmy Badr Khalaf , A. Ashour , Mostafa Y.A. Mostafa
In this study, radon (222Rn) gas concentration has been investigated in the indoor air of selected 30 homes in Baghdad city to estimate the Lung cancer risk. An active technique, the radon-scout detector, is used. The detector was placed in the middle of the living room at a height of nearly 1 m. The measuring time for each house is 7 days (166 h). The radon-scout detector measures the average exposure, maximum exposure, minimum exposure, temperature, and relative humidity (%). Results show that the average exposure in all homes is in the range from 14 ± 3 to 53 ± 4.9 Bq m−3. The maximum exposure is 307 Bq m−3, which is detected at houses1 (h1), the minimum exposure is zero, which is detected at all houses, the relative humidity ranges between 73% and 28%, the temperature ranges between 32 and 13 °C. All the estimated average radon exposures within the global limits of 200-300 Bq m−3, except one reading detected at h1 (307 Bq m−3), were slightly higher than the recommended limits. Based on measured results, the maximum potential energy of alpha concentration (PEAC) is 5.724 WLM estimated at h9, the exposure to radon progeny (EP) is ranged from 0.0623 to 0.235 WLM y−1, the annual absorbed dose rate (D) is ranged from 0.35 to 1.34 × 10−6 mSv y−1, the annual effective dose rate (ED) is ranged from 0.35 to 3.2 mSv y−1, and the lung cancer risk (LCR) is ranged between 15.1 and 57.8. Finally, it can be concluded that houses in Baghdad city are safe from radon gas as a second cause of lung cancer worldwide.
本研究对巴格达市选定的30个家庭室内空气中的氡(222Rn)气体浓度进行了调查,以估计肺癌的风险。使用了一种主动技术,即氡侦察探测器。探测器被放置在客厅的中间,高度接近1 m。每间房屋的测量时间为7天(166 h)。氡探测器测量平均暴露量、最大暴露量、最小暴露量、温度和相对湿度(%)。结果表明,所有家庭的平均暴露量为14 ± 3 ~ 53 ± 4.9 Bq m-3。最大暴露量为307 Bq m-3,在房屋1 (h1)检测到,最小暴露量为零,在所有房屋均检测到,相对湿度范围为73% ~ 28%,温度范围为32 ~ 13 °C。除在h1检测到的一个读数(307 Bq - m-3)外,所有估计的平均氡暴露量均在200-300 Bq - m-3的全球限值内,略高于建议限值。根据测量结果,h9时α浓度最大势能(PEAC)估计为5.724 WLM,氡子体暴露(EP)范围为0.0623 ~ 0.235 WLM y-1,年吸收剂量率(D)范围为0.35 ~ 1.34 × 10-6 mSv y-1,年有效剂量率(ED)范围为0.35 ~ 3.2 mSv y-1,肺癌危险度(LCR)范围为15.1 ~ 57.8。最后,可以得出结论,巴格达市的房屋是安全的,氡气是世界范围内肺癌的第二大原因。
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引用次数: 0
SMDRnet: Saliency multiscale dense residual network for multimodal medical image fusion SMDRnet:多模态医学图像融合的显著性多尺度密集残差网络
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-06-01 Epub Date: 2026-03-07 DOI: 10.1016/j.apradiso.2026.112556
Jun Fu, Jie Yang, Gengyu Ge

Background

Medical image fusion methods can provide more comprehensive and precise details about the internal structures of the human body by integrating data from multiple medical images, thereby helping doctors diagnose diseases more accurately. Meanwhile, medical fusion images can help doctors better observe and process diseased tissues, reduce the occurrence of misdiagnosis and missed diagnosis, and lower medical risks and costs. Furthermore, medical image fusion technology can also serve as a teaching tool to help medical students better understand and master relevant knowledge.

Purpose

However, current medical image fusion algorithms have drawbacks such as information loss, edge blurring, algorithm complexity, and poor real-time performance, which limit their applications.

Methods

In response to these deficiencies, this article proposes a saliency multiscale dense residual network for multimodal medical image fusion. Firstly, add the two original medical images together, and then input them into a deep convolutional neural network to extract saliency feature maps. Next, a multiscale dense residual network reconstructs the image, followed by color transformation to produce the final fusion result.

Conclusions

The experimental results show that the fusion images of the proposed algorithm have richer details, higher color fidelity, and better objective performance compared to the reference algorithms.
医学图像融合方法通过整合多幅医学图像的数据,提供更全面、更精确的人体内部结构细节,从而帮助医生更准确地诊断疾病。同时,医学融合图像可以帮助医生更好地观察和处理病变组织,减少误诊和漏诊的发生,降低医疗风险和成本。此外,医学图像融合技术还可以作为一种教学工具,帮助医学生更好地理解和掌握相关知识。然而,现有的医学图像融合算法存在信息丢失、边缘模糊、算法复杂、实时性差等缺点,限制了其应用。方法针对这些不足,提出了一种显著性多尺度密集残差网络用于多模态医学图像融合。首先将两张原始医学图像相加,然后输入深度卷积神经网络提取显著性特征图。然后,利用多尺度密集残差网络对图像进行重构,再进行颜色变换,得到最终的融合结果。实验结果表明,与参考算法相比,该算法融合图像具有更丰富的细节、更高的色彩保真度和更好的客观性能。
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引用次数: 0
Electron beam and roasting treatments of cottonseed meal: Implications for gossypol content, rumen degradability parameters and fattening performance in lambs 电子束和焙烧处理棉籽粕:对羔羊棉酚含量、瘤胃可降解性参数和育肥性能的影响
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-05-01 Epub Date: 2026-02-06 DOI: 10.1016/j.apradiso.2026.112484
Farzad Ghanbari , Hormoz Mansouri , Nader Papi , Taghi Ghoorchi , Parvin Shawrang , Noormohammad TorbatiNejad , Davood Ebrahimi Meymand , Esmaeil Esmaeili Rad
This study evaluated the nutritional value of cottonseed meal (CSM) processed by roasting (125 °C for 30 min) and electron beam (EB) irradiation (75 kGy), using both in situ and in vivo approaches. Ruminal degradation kinetics were assessed via the nylon bag technique. A fattening trial was conducted using 18 male Shal lambs (32.44 ± 5.20 kg) in a completely randomized design (CRD). The lambs were assigned to three groups (n = 6), each receiving one of the experimental diets (treatments) containing untreated CSM (control), heat-treated (roasted) CSM (RCSM), or EB-irradiated CSM (ICSM). Both processing methods reduced the effective ruminal degradability of dry matter and crude protein at outflow rates of 0.02, 0.05, and 0.08 h−1 (P < 0.05); however, EB irradiation was more effective. Blood parameters remained unaffected (P > 0.05). Notably, lambs fed ICSM exhibited higher feed intake (P = 0.02), daily weight gain (P = 0.03), total weight gain (P = 0.03), and final body weight (P = 0.04) compared with those receiving RCSM. Feed conversion ratio showed a favorable trend (P = 0.08). Additionally, hot and cold carcass weights (P = 0.02, P = 0.04) and eye muscle width (P = 0.01) were greater in the ICSM group. These results suggest that EB irradiation improves ruminal protein protection and enhances growth performance and carcass quality in fattening lambs.
本研究采用原位和体内两种方法,对经125 °C烘焙30 min和75 kGy电子束辐照处理的棉籽粕(CSM)的营养价值进行了评价。采用尼龙袋技术评价瘤胃降解动力学。采用完全随机设计(CRD),选用18只雄性夏尔羊(32.44 ± 5.20 kg)进行育肥试验。羔羊被分为三组(n = 6),每组饲喂一种试验饲粮(处理),其中包括未处理的CSM(对照)、热处理(烤)CSM (RCSM)或eb辐照CSM (ICSM)。在流出速率为0.02、0.05和0.08 h−1时,两种处理方法均降低了干物质和粗蛋白质的瘤胃有效降解率(P <; 0.05);而EB照射更有效。血液参数未受影响(P >; 0.05)。与RCSM组相比,ICSM组羔羊的采食量(P = 0.02)、日增重(P = 0.03)、总增重(P = 0.03)和末重(P = 0.04)显著增加。饲料系数呈良好趋势(P = 0.08)。此外,ICSM组热胴体重和冷胴体重(P = 0.02,P = 0.04)和眼肌宽度(P = 0.01)均大于ICSM组。综上所述,EB辐照可改善育肥羔羊瘤胃蛋白质保护,提高生长性能和胴体品质。
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引用次数: 0
Radiometric characterization of the Irati Formation at Saltinho city, São Paulo State, Brazil 巴西圣保罗州Saltinho市Irati组的辐射特征
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-05-01 Epub Date: 2026-02-12 DOI: 10.1016/j.apradiso.2026.112491
Gabrielle Roveratti, Daniel Marcos Bonotto
X-ray fluorescence (XRF) and gamma-ray spectrometry are essential analytical techniques in geological and geochemical studies, providing valuable insights into the composition, origin, and evolution of sedimentary and igneous formations. In Brazil, these methods have been increasingly applied to identify hydrocarbon-bearing regions and to characterize lithological variations across sedimentary basins. The Irati Formation, in particular, represents one of the primary hydrocarbon-generating sequences in the Paraná Basin, comprising organic-rich shales and carbonates that are capable of producing oil under suitable thermal conditions. In this context, the integration of geochemical and geophysical analyses, supported by modern computational tools, allows for a more precise interpretation of geological processes. The results revealed strong geochemical partitioning between carbonate and siliciclastic fractions, identified a hybrid lithofacies ("limestone-cucuruto"), while the K/U ratios confirmed a mineralogy poor in K-feldspars and dominated by carbonate phases. The present study applied statistical and multivariate methods using the Python programming language, enabling robust and reproducible analyses of geochemical data. This approach enhanced the understanding of the geochemical behavior of the Irati Formation, contributing to the assessment of its hydrocarbon potential within the basin's geological framework.
x射线荧光(XRF)和伽马射线能谱法是地质和地球化学研究中必不可少的分析技术,为沉积和火成岩地层的组成、起源和演化提供了有价值的见解。在巴西,这些方法越来越多地应用于识别含油气区域和表征沉积盆地的岩性变化。特别是Irati组,代表了paran盆地的主要生烃层序之一,由富有机质页岩和碳酸盐岩组成,在合适的热条件下能够生产石油。在这方面,结合地球化学和地球物理分析,在现代计算工具的支持下,可以更精确地解释地质过程。结果显示碳酸盐和硅屑组分之间存在强烈的地球化学分异,确定了一种混合岩相(“灰岩-库古鲁托”),而K/U比值证实了钾长石的矿物学特征较差,以碳酸盐相为主。本研究使用Python编程语言应用统计和多元方法,实现了对地球化学数据的鲁棒性和可重复性分析。该方法增强了对Irati组地球化学行为的理解,有助于在盆地地质框架内评估其油气潜力。
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引用次数: 0
Pure fungal melanin: green bioproduction, characterization, niosomal formulation, radiolabeling, and in vivo biodistribution as a probe for photothermal therapy of cancer 纯真菌黑色素:绿色生物产生、表征、niosomal配方、放射性标记和体内生物分布作为光热治疗癌症的探针
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-05-01 Epub Date: 2026-02-05 DOI: 10.1016/j.apradiso.2026.112475
Zainab S. Nasr , Yasmeen A. Hasanien , Mahmoud A. Mosleh , Mohamed H. Aboumanei
Studying the biosynthesis of melanin from biological sources is essential due to the expanding demand for natural materials in various industries. The fungus Aspergillus luchuensis in the current study developed the extracellular melanin pigment. Aspergillus luchuensis AUMC 16931 was isolated from dye factory wastewater and identified by 18S-rRNA gene as the most potent one from 5 isolates. Optimized conditions boosted melanin production, and the pigment was encapsulated into niosomes using the ether injection method, forming stable, lipid-based nanocarriers. These melanin-loaded niosomes (MN) were tagged with technetium-99m (99mTc) to track their journey in living organisms. By injecting them directly into tumors in mice, their distribution was studied, revealing impressive tumor accumulation and retention. These results suggest that melanin-loaded niosomes hold great promise as a tool for photothermal cancer therapy, using targeted heat to combat tumors effectively.
由于各个行业对天然材料的需求不断扩大,研究从生物来源合成黑色素是必不可少的。本研究的真菌葡曲霉产生了细胞外黑色素。从印染厂废水中分离到葡曲霉AUMC 16931,经18S-rRNA基因鉴定为5株菌株中最强的菌株。优化后的条件促进了黑色素的生成,并通过醚注射法将黑色素包裹在乳小体中,形成稳定的脂质纳米载体。这些装载黑色素的niosome (MN)用锝-99m (99mTc)标记,以跟踪它们在生物体中的旅程。通过将它们直接注射到小鼠肿瘤中,研究了它们的分布,揭示了令人印象深刻的肿瘤积累和保留。这些结果表明,装载黑色素的niosome作为光热癌症治疗的工具具有很大的前景,利用靶向热量有效地对抗肿瘤。
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引用次数: 0
Limit test for cobalt-60 in carbon-14 urea capsules by liquid scintillation counting 用液体闪烁计数法测定碳-14尿素胶囊中钴-60的限量
IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Pub Date : 2026-05-01 Epub Date: 2026-02-10 DOI: 10.1016/j.apradiso.2026.112488
Yadong Wang , Yi Wang , Xiongxin Dai
A new method to determine the 60Co impurity in 14C-urea capsules by liquid scintillation counting (LSC) has been developed. In this method, the counting signals produced by the Compton electrons of 60Co is used for 60Co analysis by selecting an appropriate region of interest in the LSC spectrum of the 14C-urea capsule sample. The spectral interferences caused by the high-activity 14C and the quench effect can be effectively eliminated by using a fixed sample preparation procedure. This method was validated by standard addition method using the commercial 14C-urea capsules and the results of 60Co activity are in good agreement with the expected values. The sensitivity of this method is calculated as ≤0.0064% for 60Co content and sufficiently competent for the limit test of <0.1% radio-impurity (including 60Co) in 14C-urea capsules. The method provides a practicable guidance for the radionuclidic purity test of 14C-urea capsules using LSC and can be directly applied in the routine quality test of 14C-urea capsules.
建立了液体闪烁计数法测定14c -尿素胶囊中60Co杂质的新方法。在该方法中,60Co的康普顿电子产生的计数信号通过在14c -尿素胶囊样品的LSC光谱中选择合适的感兴趣区域用于60Co分析。采用固定的制样工艺,可以有效地消除高活性14C和淬火效应引起的光谱干扰。用14c -尿素胶囊的标准加成法对该方法进行了验证,60Co活性与预测值吻合较好。计算出该方法对60Co含量的灵敏度≤0.0064%,足以满足14c -尿素胶囊中<;0.1%放射性杂质(含60Co)的限检。该方法为LSC法检测14c -尿素胶囊的放射性核素纯度提供了切实可行的指导,可直接用于14c -尿素胶囊的常规质量检测。
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Applied Radiation and Isotopes
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