Pub Date : 2021-07-23DOI: 10.1080/05704928.2021.1955702
M. Mabrouk, Nouran A. Hamed, F. Mansour
Abstract The applications of surfactants in various fields are gaining more attention, which makes full characterization of surfactants of growing interest. It is fundamental to measure the critical micelle concentration (CMC) as a parameter for characterizing surfactants. Spectroscopic methods for determination of CMC are more common, easier to perform, and in certain applications more accurate. In this review, different spectroscopic techniques and methods used for determination of CMC are discussed. These methods include direct UV/VIS Spectroscopy, which studies liquid surface curvature in thin wells using vertical detecting light beam with the wavelength set at 900 nm. The indirect UV/VIS Spectroscopic methods include using surface plasmon resonance or surface-enhanced Raman scattering of metal nanoparticles. Direct spectrofluorometric methods measure CMC based on the intrinsic fluorescence of the tested surfactants, and it was reserved for surfactants with intrinsic fluorescence such as Triton-X100. Indirect spectrofluorometric methods include measuring the change in fluorescence intensity, spectral shape, lifetime, polarization, or the solvatochromic shift of surfactant-dye solution. Other spectroscopic methods have been reported such as X-ray diffraction, nuclear magnetic resonance spectroscopy and small-angle neutron scattering. This review article discusses the spectroscopic methods developed for CMC determination with emphasis on the principle, applications, advantages, and limitations of each method.
{"title":"Spectroscopic methods for determination of critical micelle concentrations of surfactants; a comprehensive review","authors":"M. Mabrouk, Nouran A. Hamed, F. Mansour","doi":"10.1080/05704928.2021.1955702","DOIUrl":"https://doi.org/10.1080/05704928.2021.1955702","url":null,"abstract":"Abstract The applications of surfactants in various fields are gaining more attention, which makes full characterization of surfactants of growing interest. It is fundamental to measure the critical micelle concentration (CMC) as a parameter for characterizing surfactants. Spectroscopic methods for determination of CMC are more common, easier to perform, and in certain applications more accurate. In this review, different spectroscopic techniques and methods used for determination of CMC are discussed. These methods include direct UV/VIS Spectroscopy, which studies liquid surface curvature in thin wells using vertical detecting light beam with the wavelength set at 900 nm. The indirect UV/VIS Spectroscopic methods include using surface plasmon resonance or surface-enhanced Raman scattering of metal nanoparticles. Direct spectrofluorometric methods measure CMC based on the intrinsic fluorescence of the tested surfactants, and it was reserved for surfactants with intrinsic fluorescence such as Triton-X100. Indirect spectrofluorometric methods include measuring the change in fluorescence intensity, spectral shape, lifetime, polarization, or the solvatochromic shift of surfactant-dye solution. Other spectroscopic methods have been reported such as X-ray diffraction, nuclear magnetic resonance spectroscopy and small-angle neutron scattering. This review article discusses the spectroscopic methods developed for CMC determination with emphasis on the principle, applications, advantages, and limitations of each method.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"6 1","pages":"206 - 234"},"PeriodicalIF":6.1,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77060688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-13DOI: 10.1080/05704928.2021.1946822
S. Magalhães, B. Goodfellow, A. Nunes
Abstract Fourier Transform Infrared (FTIR) Spectroscopy, in particular ATR-FTIR, is a widely used technique that allows, in a very short time, to screen biological samples and to identify its specific spectral signature, being an important tool for clinical diagnosis and biomarker discovery. FTIR spectroscopy is used to screen cells, tissues and biofluids and is already implemented in biomedicine, mainly in pre-clinical setting. Although the experimental procedure is easy to implement, sample preparation, definition of spectra acquisition parameters and spectral analysis are crucial steps to obtain reliable and reproducible results. However, the selection of experimental conditions for spectral analysis can be a difficult task for researchers because the information is dispersed and often the choice is made in an empirical and inaccurate way. This review gathers and summarizes studies using FTIR in pre-clinical and clinical setting and aims to systematize information and propose some guidelines for FTIR spectroscopy studies of biological samples. This will help new users to prepare samples for FTIR analysis and understand the critical steps to correctly perform spectra pretreatment, preprocessing and statistical analysis and to implement appropriate and evidence-based experimental designs.
{"title":"FTIR spectroscopy in biomedical research: how to get the most out of its potential","authors":"S. Magalhães, B. Goodfellow, A. Nunes","doi":"10.1080/05704928.2021.1946822","DOIUrl":"https://doi.org/10.1080/05704928.2021.1946822","url":null,"abstract":"Abstract Fourier Transform Infrared (FTIR) Spectroscopy, in particular ATR-FTIR, is a widely used technique that allows, in a very short time, to screen biological samples and to identify its specific spectral signature, being an important tool for clinical diagnosis and biomarker discovery. FTIR spectroscopy is used to screen cells, tissues and biofluids and is already implemented in biomedicine, mainly in pre-clinical setting. Although the experimental procedure is easy to implement, sample preparation, definition of spectra acquisition parameters and spectral analysis are crucial steps to obtain reliable and reproducible results. However, the selection of experimental conditions for spectral analysis can be a difficult task for researchers because the information is dispersed and often the choice is made in an empirical and inaccurate way. This review gathers and summarizes studies using FTIR in pre-clinical and clinical setting and aims to systematize information and propose some guidelines for FTIR spectroscopy studies of biological samples. This will help new users to prepare samples for FTIR analysis and understand the critical steps to correctly perform spectra pretreatment, preprocessing and statistical analysis and to implement appropriate and evidence-based experimental designs.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"163 1","pages":"869 - 907"},"PeriodicalIF":6.1,"publicationDate":"2021-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86446258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.1080/05704928.2021.1944175
Guadalupe Donjuán-Loredo, R. Espinosa‐Tanguma, M. Ramírez-Elías
Abstract Metabolic syndrome (MetS) is defined as a set of metabolic disorders, including central obesity, dyslipidemia, arterial hypertension, and hyperglycemia. The prevalence of MetS is increasing in epidemic proportions in both developed and developing countries. MetS increment has been paralleled by the growing epidemic of type-2 diabetes, hypertension, cardiovascular disease, and obesity. Raman spectroscopy is a noninvasive optical technique that has been used in MetS and associated diseases as an alternative to more invasive routine laboratory studies. Raman Spectroscopy's medical diagnosis application is based on the fact that the molecular composition of healthy tissues or biofluids changes due to disease. Identifying biomarkers with this technique can be used for early diagnosis, monitoring disease evolution, and response to treatment. This article reviews recent applications which demonstrate the potential of Raman spectroscopy in the assessment of MetS diseases.
{"title":"Raman spectroscopy in the diagnosis of metabolic syndrome","authors":"Guadalupe Donjuán-Loredo, R. Espinosa‐Tanguma, M. Ramírez-Elías","doi":"10.1080/05704928.2021.1944175","DOIUrl":"https://doi.org/10.1080/05704928.2021.1944175","url":null,"abstract":"Abstract Metabolic syndrome (MetS) is defined as a set of metabolic disorders, including central obesity, dyslipidemia, arterial hypertension, and hyperglycemia. The prevalence of MetS is increasing in epidemic proportions in both developed and developing countries. MetS increment has been paralleled by the growing epidemic of type-2 diabetes, hypertension, cardiovascular disease, and obesity. Raman spectroscopy is a noninvasive optical technique that has been used in MetS and associated diseases as an alternative to more invasive routine laboratory studies. Raman Spectroscopy's medical diagnosis application is based on the fact that the molecular composition of healthy tissues or biofluids changes due to disease. Identifying biomarkers with this technique can be used for early diagnosis, monitoring disease evolution, and response to treatment. This article reviews recent applications which demonstrate the potential of Raman spectroscopy in the assessment of MetS diseases.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"81 1","pages":"159 - 179"},"PeriodicalIF":6.1,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80491666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-28DOI: 10.1080/05704928.2021.1942894
M. Jansson, Martin Kögler, S. Hörkkö, T. Ala-Kokko, L. Rieppo
Abstract Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of the vibrational spectroscopic techniques applied in microbiology during the past decade. In addition, future applications of the elaborated spectroscopic techniques will be highlighted. The results of this review show that both FTIR and Raman spectroscopy are promising alternatives to conventional diagnostic approaches because they provide label-free and noninvasive bacterial detection, identification, and antibiotic susceptibility testing in a single step. Cost-effective, accurate, and rapid tests are needed in order to improve diagnostics and patient care, to decrease the use of unnecessary antimicrobial agents, to prevent resistant microbials, and to decrease the overall burden of outbreaks. Prior to that, however, the presented approaches need to be validated in a clinical workflow against the conventional diagnostic approaches.
{"title":"Vibrational spectroscopy and its future applications in microbiology","authors":"M. Jansson, Martin Kögler, S. Hörkkö, T. Ala-Kokko, L. Rieppo","doi":"10.1080/05704928.2021.1942894","DOIUrl":"https://doi.org/10.1080/05704928.2021.1942894","url":null,"abstract":"Abstract Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of the vibrational spectroscopic techniques applied in microbiology during the past decade. In addition, future applications of the elaborated spectroscopic techniques will be highlighted. The results of this review show that both FTIR and Raman spectroscopy are promising alternatives to conventional diagnostic approaches because they provide label-free and noninvasive bacterial detection, identification, and antibiotic susceptibility testing in a single step. Cost-effective, accurate, and rapid tests are needed in order to improve diagnostics and patient care, to decrease the use of unnecessary antimicrobial agents, to prevent resistant microbials, and to decrease the overall burden of outbreaks. Prior to that, however, the presented approaches need to be validated in a clinical workflow against the conventional diagnostic approaches.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"2 1","pages":"132 - 158"},"PeriodicalIF":6.1,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90322200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-12DOI: 10.1080/05704928.2021.1930552
Shiyan Fang, Ruiyan Cui, Yan Wang, Yanru Zhao, Keqiang Yu, Ao Jiang
Abstract Tree diseases endanger forestry and fruit tree plantations seriously worldwide in the past decades, leading to significant economic losses for the agricultural production sector. Rapid and accurate detection of tree diseases is crucial in tree protection. Despite molecular biological detection methods have prominent specificity, they are time-consuming and laborious, and are not suitable for large-scale detection of tree diseases. Spectroscopy with nondestructive, rapid, and high throughput characteristics has been applied to plant disease detection. Spectral detection systems are divided into three categories according to the spectrometer's carrying platform: portable hand-held spectrometer, airborne vehicle-mounted spectrometer, and large laboratory spectrometer. This review summarized three main spectral detection systems and their advantages and disadvantages in detecting various diseases of forestry and fruit trees: including detection of the single disease, multiple stress, and early disease using Visible/near-infrared, Raman, and hyperspectral imaging. Finally, spectroscopy detection technology applications of challenges were summarized, highlighting future trends.
{"title":"Application of multiple spectral systems for the tree disease detection: A review","authors":"Shiyan Fang, Ruiyan Cui, Yan Wang, Yanru Zhao, Keqiang Yu, Ao Jiang","doi":"10.1080/05704928.2021.1930552","DOIUrl":"https://doi.org/10.1080/05704928.2021.1930552","url":null,"abstract":"Abstract Tree diseases endanger forestry and fruit tree plantations seriously worldwide in the past decades, leading to significant economic losses for the agricultural production sector. Rapid and accurate detection of tree diseases is crucial in tree protection. Despite molecular biological detection methods have prominent specificity, they are time-consuming and laborious, and are not suitable for large-scale detection of tree diseases. Spectroscopy with nondestructive, rapid, and high throughput characteristics has been applied to plant disease detection. Spectral detection systems are divided into three categories according to the spectrometer's carrying platform: portable hand-held spectrometer, airborne vehicle-mounted spectrometer, and large laboratory spectrometer. This review summarized three main spectral detection systems and their advantages and disadvantages in detecting various diseases of forestry and fruit trees: including detection of the single disease, multiple stress, and early disease using Visible/near-infrared, Raman, and hyperspectral imaging. Finally, spectroscopy detection technology applications of challenges were summarized, highlighting future trends.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"34 1","pages":"83 - 109"},"PeriodicalIF":6.1,"publicationDate":"2021-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78834484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-04DOI: 10.1080/05704928.2021.1935272
Qingsheng Bai, Yongguang Yin, Yanwanjing Liu, Haowen Jiang, Mengxin Wu, Weidong Wang, Zhiqiang Tan, Jing-fu Liu, M. Moon, B. Xing
Abstract Due to the increased applications of engineered elemental metal nanoparticles (EMNPs) in recent years, increased attention has been devoted to their release into the environment. EMNPs pose potential risks to living organisms, including human beings. Hence, the characterization of EMNPs in the environment has gained significant importance. Among the various techniques reported for the characterization of EMNPs, on-line coupling of flow field-flow fractionation with inductively coupled plasma mass spectrometry (F4-ICPMS) has been well established for the simultaneous separation, identification, and quantification of EMNPs, especially in the complex matrices of environmental samples. Thus, this review focuses on the specific advantages of the F4 method, especially the asymmetrical F4 (AF4) and hollow fiber F4 (HF5) methods, in the separation of EMNPs, the general development of AF4-ICPMS and HF5-ICPMS techniques, and recent advances in the application of these hyphenated techniques in examining the occurrence and transformation of EMNPs in the environment. Finally, several perspectives on these techniques have been put forward.
{"title":"Flow field-flow fractionation hyphenated with inductively coupled plasma mass spectrometry: a robust technique for characterization of engineered elemental metal nanoparticles in the environment","authors":"Qingsheng Bai, Yongguang Yin, Yanwanjing Liu, Haowen Jiang, Mengxin Wu, Weidong Wang, Zhiqiang Tan, Jing-fu Liu, M. Moon, B. Xing","doi":"10.1080/05704928.2021.1935272","DOIUrl":"https://doi.org/10.1080/05704928.2021.1935272","url":null,"abstract":"Abstract Due to the increased applications of engineered elemental metal nanoparticles (EMNPs) in recent years, increased attention has been devoted to their release into the environment. EMNPs pose potential risks to living organisms, including human beings. Hence, the characterization of EMNPs in the environment has gained significant importance. Among the various techniques reported for the characterization of EMNPs, on-line coupling of flow field-flow fractionation with inductively coupled plasma mass spectrometry (F4-ICPMS) has been well established for the simultaneous separation, identification, and quantification of EMNPs, especially in the complex matrices of environmental samples. Thus, this review focuses on the specific advantages of the F4 method, especially the asymmetrical F4 (AF4) and hollow fiber F4 (HF5) methods, in the separation of EMNPs, the general development of AF4-ICPMS and HF5-ICPMS techniques, and recent advances in the application of these hyphenated techniques in examining the occurrence and transformation of EMNPs in the environment. Finally, several perspectives on these techniques have been put forward.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"37 1","pages":"110 - 131"},"PeriodicalIF":6.1,"publicationDate":"2021-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89833532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.1080/05704928.2021.1920030
S. Dell’Orco, S. Rowland, A. Harman-Ware, D. Carpenter, T. Foust, E. Christensen, C. Mukarakate
Abstract A promising approach for supplementing petroleum-derived fuels to support reductions in green-house gas emissions is to convert abundant biomass feedstocks into renewable carbon-rich oils using pyrolysis. However, the resultant bio-oils contain various oxygenated compounds that can impart acidity, chemical and thermal instability, and immiscibility with petroleum derived fuels, necessitating further upgrading to derive fuel blendstocks. Co-processing bio-oils and petroleum-derived liquids in existing refineries is a potentially near-term, cost-effective approach for upgrading bio-oils while reducing refinery carbon intensities. However, one cause for hesitation in co-processing bio-oils is limited comprehensive characterization and speciation of the bio-oil components. Advanced analytical techniques are currently under investigation to enable identification of elusive species in bio-oils, enabling researchers to develop strategies to mitigate catalyst deactivation agents and contaminants. This review provides a brief overview of several analytical methods commonly used to analyze bio-oils and their limitations. In addition, advanced techniques currently under development are discussed to further elucidate bio-oil components that may limit its end use. This will help inform the technical and economic feasibility of co-processing bio-oils with petroleum-derived liquids, therefore, improving the overall downstream processes for biofuels blendstock production.
{"title":"Advanced spectrometric methods for characterizing bio-oils to enable refineries to reduce fuel carbon intensity during co-processing","authors":"S. Dell’Orco, S. Rowland, A. Harman-Ware, D. Carpenter, T. Foust, E. Christensen, C. Mukarakate","doi":"10.1080/05704928.2021.1920030","DOIUrl":"https://doi.org/10.1080/05704928.2021.1920030","url":null,"abstract":"Abstract A promising approach for supplementing petroleum-derived fuels to support reductions in green-house gas emissions is to convert abundant biomass feedstocks into renewable carbon-rich oils using pyrolysis. However, the resultant bio-oils contain various oxygenated compounds that can impart acidity, chemical and thermal instability, and immiscibility with petroleum derived fuels, necessitating further upgrading to derive fuel blendstocks. Co-processing bio-oils and petroleum-derived liquids in existing refineries is a potentially near-term, cost-effective approach for upgrading bio-oils while reducing refinery carbon intensities. However, one cause for hesitation in co-processing bio-oils is limited comprehensive characterization and speciation of the bio-oil components. Advanced analytical techniques are currently under investigation to enable identification of elusive species in bio-oils, enabling researchers to develop strategies to mitigate catalyst deactivation agents and contaminants. This review provides a brief overview of several analytical methods commonly used to analyze bio-oils and their limitations. In addition, advanced techniques currently under development are discussed to further elucidate bio-oil components that may limit its end use. This will help inform the technical and economic feasibility of co-processing bio-oils with petroleum-derived liquids, therefore, improving the overall downstream processes for biofuels blendstock production.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"31 1","pages":"77 - 87"},"PeriodicalIF":6.1,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87094712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-12DOI: 10.1080/05704928.2021.1916516
M. Bezerra, Uillian Mozart Ferreira da Mata Cerqueira, S. Ferreira, C. Novaes, F. C. Novais, G. S. Valasques, Bruno Novaes da Silva
Abstract This review addresses the use of cloud point extraction as a separation and pre-concentration method aiming at the speciation of metals and metalloids by spectroanalytical techniques. The principles, advantages and limitations of this technique are presented for a better understanding of its potential. The main strategies for using cloud point extraction in carrying out speciation analysis are discussed. To illustrate its applicability in the development of analytical methodologies aimed at speciation, some works found in the specialized literature are commented, highlighting their contribution to the theme. Finally, future trends for the development in this field (such as speciation of anionic species, cloud point micro extraction, speciation of nanoparticles, among others) is presented and discussed.
{"title":"Recent developments in the application of cloud point extraction as procedure for speciation of trace elements","authors":"M. Bezerra, Uillian Mozart Ferreira da Mata Cerqueira, S. Ferreira, C. Novaes, F. C. Novais, G. S. Valasques, Bruno Novaes da Silva","doi":"10.1080/05704928.2021.1916516","DOIUrl":"https://doi.org/10.1080/05704928.2021.1916516","url":null,"abstract":"Abstract This review addresses the use of cloud point extraction as a separation and pre-concentration method aiming at the speciation of metals and metalloids by spectroanalytical techniques. The principles, advantages and limitations of this technique are presented for a better understanding of its potential. The main strategies for using cloud point extraction in carrying out speciation analysis are discussed. To illustrate its applicability in the development of analytical methodologies aimed at speciation, some works found in the specialized literature are commented, highlighting their contribution to the theme. Finally, future trends for the development in this field (such as speciation of anionic species, cloud point micro extraction, speciation of nanoparticles, among others) is presented and discussed.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"114 1","pages":"338 - 352"},"PeriodicalIF":6.1,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87990672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-12DOI: 10.1080/05704928.2021.1918703
Ziyan Li, Rui Liu, Yi Lv
Abstract Recent developments in multiplex bioassay around the theme of precision diagnostics have gained great focus. Inductively coupled plasma mass spectrometry (ICPMS) is emerging as a powerful platform for multiplex bioassay due to its high sensitivity, wide dynamic range, particularly its reliable multiplex sensing ability. This review discusses the progress being made in the multiplex bioassay applicating ICPMS, mainly emphasizes on varieties of biomarkers and methodological innovations. Also, we summarized limitations and proposed prospects to shed new light on the emergence of more powerful and application-oriented analytical methods.
{"title":"ICPMS based multiplexed bioassay: Principles, approaches and progresses","authors":"Ziyan Li, Rui Liu, Yi Lv","doi":"10.1080/05704928.2021.1918703","DOIUrl":"https://doi.org/10.1080/05704928.2021.1918703","url":null,"abstract":"Abstract Recent developments in multiplex bioassay around the theme of precision diagnostics have gained great focus. Inductively coupled plasma mass spectrometry (ICPMS) is emerging as a powerful platform for multiplex bioassay due to its high sensitivity, wide dynamic range, particularly its reliable multiplex sensing ability. This review discusses the progress being made in the multiplex bioassay applicating ICPMS, mainly emphasizes on varieties of biomarkers and methodological innovations. Also, we summarized limitations and proposed prospects to shed new light on the emergence of more powerful and application-oriented analytical methods.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"53 5 1","pages":"39 - 64"},"PeriodicalIF":6.1,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75994499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-06DOI: 10.1080/05704928.2021.1919896
D. Butcher
Abstract Graphite furnace atomic absorption spectrometry (GFAAS) is a highly sensitive method for the determination of elements in samples while requiring a low sample volume. The analytes are converted to atoms at high temperatures in an electrothermally heated atomizer. Although line-source GFAAS continues to widely employed, high-resolution continuum source (HR-CS) GFAAS offers more accurate correction for matrix-induced spectral backgrounds. This article reviews recent innovations and developments in GFAAS, including instrumentation; the characterization of fundamental properties; progress in HR-CS GFAAS; sample preparation procedures including vapor generation, solid, and slurry sampling; elemental speciation; preconcentration/separation protocols; and direct analysis. The conclusion summarizes major developments and future directions in GFAAS.
{"title":"Innovations and developments in graphite furnace atomic absorption spectrometry (GFAAS)","authors":"D. Butcher","doi":"10.1080/05704928.2021.1919896","DOIUrl":"https://doi.org/10.1080/05704928.2021.1919896","url":null,"abstract":"Abstract Graphite furnace atomic absorption spectrometry (GFAAS) is a highly sensitive method for the determination of elements in samples while requiring a low sample volume. The analytes are converted to atoms at high temperatures in an electrothermally heated atomizer. Although line-source GFAAS continues to widely employed, high-resolution continuum source (HR-CS) GFAAS offers more accurate correction for matrix-induced spectral backgrounds. This article reviews recent innovations and developments in GFAAS, including instrumentation; the characterization of fundamental properties; progress in HR-CS GFAAS; sample preparation procedures including vapor generation, solid, and slurry sampling; elemental speciation; preconcentration/separation protocols; and direct analysis. The conclusion summarizes major developments and future directions in GFAAS.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"18 1","pages":"65 - 82"},"PeriodicalIF":6.1,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85049833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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