Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000165
R. Charvet, C. Cun, P. Leroy
The increasing use of plastics in our society makes the vinyl chloride a potential source of pollution for environment. Related to its toxicity and presence in the environment, the new European Directive for drinking water quality includes now a limit for its concentration in drinking water. Currently a government needs new analytical methods to analyse this pollutant. T his study concerns the optimization of the headspace solid-phase microextraction (HS-SPME) combined with gas chromatography- ion trap mass spectrometry for the vinyl chloride analysis in liquid and solid samples. The Carboxen PDMS (Polydimethylsiloxane) 75 µm fibre allows a limit of detection of 50 ppt and 100 ppt as a limit of quan- tification in linearity and repeatability conditions useful for control analysis. Moreover, the excellent affinity between this fibre and the molecule of interest makes the use of little volumes of samples possible. Each parameter had been optimized to obtain the best sensibility. This method has also been applied to materials.
{"title":"Vinyl chloride analysis with Solid Phase Microextraction (SPME)/GC/MS applied to analysis in materials and aqueous samples","authors":"R. Charvet, C. Cun, P. Leroy","doi":"10.1051/ANALUSIS:2000165","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000165","url":null,"abstract":"The increasing use of plastics in our society makes the vinyl chloride a potential source of pollution for environment. Related to its toxicity and presence in the environment, the new European Directive for drinking water quality includes now a limit for its concentration in drinking water. Currently a government needs new analytical methods to analyse this pollutant. T his study concerns the optimization of the headspace solid-phase microextraction (HS-SPME) combined with gas chromatography- ion trap mass spectrometry for the vinyl chloride analysis in liquid and solid samples. The Carboxen PDMS (Polydimethylsiloxane) 75 µm fibre allows a limit of detection of 50 ppt and 100 ppt as a limit of quan- tification in linearity and repeatability conditions useful for control analysis. Moreover, the excellent affinity between this fibre and the molecule of interest makes the use of little volumes of samples possible. Each parameter had been optimized to obtain the best sensibility. This method has also been applied to materials.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"137 1","pages":"980-987"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89297921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000161
G. Fernández-Martínez, P. López‐Mahía, S. Muniategui-Lorenzo, D. Prada-Rodríguez
This work proposes a method for quantifying volatile organic compounds (VOCs) in coal, fly ash and slag, coming from coal-fired power stations, using direct thermal desorption coupled with gas chromatography (GC) and mass spectrometry (MS) detection. The described method requires practically no sample handling and is precise and sensitive. Aromatic and aliphat ic hydrocarbons (benzene, toluene, alkylbenzes, heptane and octane) are the most abundant compounds in these solid samples, coal samples presenting higher levels than fly ash and slag. Other compounds (acids, ketones, aldehydes, limonene, etc.) were identi- fied by mass spectrometry.
{"title":"Determination of volatile organic compounds in coal, fly ash and slag samples by direct thermal desorption/GC/ms","authors":"G. Fernández-Martínez, P. López‐Mahía, S. Muniategui-Lorenzo, D. Prada-Rodríguez","doi":"10.1051/ANALUSIS:2000161","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000161","url":null,"abstract":"This work proposes a method for quantifying volatile organic compounds (VOCs) in coal, fly ash and slag, coming from coal-fired power stations, using direct thermal desorption coupled with gas chromatography (GC) and mass spectrometry (MS) detection. The described method requires practically no sample handling and is precise and sensitive. Aromatic and aliphat ic hydrocarbons (benzene, toluene, alkylbenzes, heptane and octane) are the most abundant compounds in these solid samples, coal samples presenting higher levels than fly ash and slag. Other compounds (acids, ketones, aldehydes, limonene, etc.) were identi- fied by mass spectrometry.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"58 1","pages":"953-959"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77877108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000166
H. Belevi, H. Mönch
An oxidative high pressure digestion method is presented to dissolve fluorine, chlorine and sulfur components of munic- ipal solid waste incinerator residues. It is a combination of the classical high pressure digestion technique with the combusti on in a closed system. The concentration determination is carried out by ion chromatography. The results are compared with those obtained by other digestion and extraction methods combined also with ion chromatography. A CNS-analyzer is used as a fur- ther method to compare the sulfur concentrations. Based on the obtained data, the accuracy of the fluorine, chlorine and sulfur concentrations is estimated as better than 85 %. It is concluded, that the oxidative high pressure digestion combined with ion chromatography is an appropriate method to determine fluorine, chlorine and sulfur concentrations in incinerator residues. Its main advantage is the simultaneous analysis of these three elements. However, it is a time consuming method.
{"title":"Simultaneous determination of fluorine, chlorine and sulfur in incinerator residues by oxidative high pressure digestion and ion chromatography","authors":"H. Belevi, H. Mönch","doi":"10.1051/ANALUSIS:2000166","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000166","url":null,"abstract":"An oxidative high pressure digestion method is presented to dissolve fluorine, chlorine and sulfur components of munic- ipal solid waste incinerator residues. It is a combination of the classical high pressure digestion technique with the combusti on in a closed system. The concentration determination is carried out by ion chromatography. The results are compared with those obtained by other digestion and extraction methods combined also with ion chromatography. A CNS-analyzer is used as a fur- ther method to compare the sulfur concentrations. Based on the obtained data, the accuracy of the fluorine, chlorine and sulfur concentrations is estimated as better than 85 %. It is concluded, that the oxidative high pressure digestion combined with ion chromatography is an appropriate method to determine fluorine, chlorine and sulfur concentrations in incinerator residues. Its main advantage is the simultaneous analysis of these three elements. However, it is a time consuming method.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"10 1","pages":"988-994"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84094893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000280895
J. Wolfender, P. Waridel, K. Ndjoko, K. Hobby, H. Major, K. Hostettmann
LC/MS/MS is becoming a very important tool for the on-line identification of natural products in crude plant extracts. For an efficient use of this technique in the dereplication of natural products, a careful study of the parameters used to generate informative MS/MS spectra is needed. In this paper the CID MS/MS spectra of ubiquitous flavonoids and related plant constituents have been systematically studied using hybrid quadrupole time of flight (Q-TOF) and ion trap (IT) mass analysers under various CID energy conditions. The results demonstrate that, if for hydroxylated flavonoids the CID MS/MS spectra generated on both instruments are similar, for partially methoxylated derivatives, important differences are observed hampering the creation of MS/MS databases exchangeable between instruments. Generally, fragments issued from C-ring cleavage, corresponding to those classically reported, were recorded but they were more easily observed on a Q-TOF instrument while losses of small molecules were favoured in IT-MS. MS/MS spectra recorded in the positive ion mode were more informative than those obtained from negative ions. For the assignment of flavonoids product ion spectra, on-line accurate mass measurement of all MS/MS fragments was obtained on the Q-TOF, while the multiple stage MSn capability of the ion trap was used to prove fragmentation pathways
{"title":"Evaluation of Q-TOF-MS/MS and multiple stage IT-MSn for the dereplication of flavonoids and related compounds in crude plant extracts","authors":"J. Wolfender, P. Waridel, K. Ndjoko, K. Hobby, H. Major, K. Hostettmann","doi":"10.1051/ANALUSIS:2000280895","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000280895","url":null,"abstract":"LC/MS/MS is becoming a very important tool for the on-line identification of natural products in crude plant extracts. For an efficient use of this technique in the dereplication of natural products, a careful study of the parameters used to generate informative MS/MS spectra is needed. In this paper the CID MS/MS spectra of ubiquitous flavonoids and related plant constituents have been systematically studied using hybrid quadrupole time of flight (Q-TOF) and ion trap (IT) mass analysers under various CID energy conditions. The results demonstrate that, if for hydroxylated flavonoids the CID MS/MS spectra generated on both instruments are similar, for partially methoxylated derivatives, important differences are observed hampering the creation of MS/MS databases exchangeable between instruments. Generally, fragments issued from C-ring cleavage, corresponding to those classically reported, were recorded but they were more easily observed on a Q-TOF instrument while losses of small molecules were favoured in IT-MS. MS/MS spectra recorded in the positive ion mode were more informative than those obtained from negative ions. For the assignment of flavonoids product ion spectra, on-line accurate mass measurement of all MS/MS fragments was obtained on the Q-TOF, while the multiple stage MSn capability of the ion trap was used to prove fragmentation pathways","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"3 1","pages":"895-906"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86406163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000280914
L. Debrauwer
The use of LC-MS/MS in the identification of xenobic metabolism pathawys in animals is described, on the basis of selected examples in the field of toxixologically relevant growth promoting agents. The structural elucidation of xenobiotic metabollites in complex biological matrices is archieved using various analytical methods and strategies using LC-MS with ESI or APCI ionisation techniques in combination with in-source CAD or MS/MS experiments. The use of some particular analytical tools (e.g. H/D exchange or MSn multisequential experiments) for solving specific structural ambiguities is also discussed.
{"title":"Use of LC-MS/MS for xenobiotic metabolism studies in animals","authors":"L. Debrauwer","doi":"10.1051/ANALUSIS:2000280914","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000280914","url":null,"abstract":"The use of LC-MS/MS in the identification of xenobic metabolism pathawys in animals is described, on the basis of selected examples in the field of toxixologically relevant growth promoting agents. The structural elucidation of xenobiotic metabollites in complex biological matrices is archieved using various analytical methods and strategies using LC-MS with ESI or APCI ionisation techniques in combination with in-source CAD or MS/MS experiments. The use of some particular analytical tools (e.g. H/D exchange or MSn multisequential experiments) for solving specific structural ambiguities is also discussed.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"28 1","pages":"914-920"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82585571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000163
E. Dupuit, A. Dandrieux, P. Kvapil, J. Ollivier, G. Dusserre, O. Thomas
The need for gas compound measurement concerns overall three domains: environmental monitoring, emission mea- surement and risk assessment. These fields are different because of concentration range (from 10 -3 to thousands mg.m-3). A fast technique has been developed based on UV spectrophotometry. Simple robust optics and absence of interference from water vapour and carbon dioxide are two of the main benefits of this method. All measurements are performed with a quartz flow cell of 10 cm pathlength. In this condition, the detection limits of various compounds (ammonia, hydrogen sulphide, sulphur dioxide, benzene, toluene, ethylbenzene and p-xylene) vary between 30 and 100 mg.m-3. This UV spectrometry system has been tested with success in two applications. The first one is during gaseous ammonia dispersion, simulating a chemical accident. The sec- ond one is BTEX monitoring measurement in a process control of soil remediation. In this case, UV is associated with spectral data treatment software. All results are compared with reference methods (Nessler reagent for ammonia, gas chromatography for BTEX). An acceptable agreement was found.
{"title":"UV spectrophotometry for monitoring toxic gases","authors":"E. Dupuit, A. Dandrieux, P. Kvapil, J. Ollivier, G. Dusserre, O. Thomas","doi":"10.1051/ANALUSIS:2000163","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000163","url":null,"abstract":"The need for gas compound measurement concerns overall three domains: environmental monitoring, emission mea- surement and risk assessment. These fields are different because of concentration range (from 10 -3 to thousands mg.m-3). A fast technique has been developed based on UV spectrophotometry. Simple robust optics and absence of interference from water vapour and carbon dioxide are two of the main benefits of this method. All measurements are performed with a quartz flow cell of 10 cm pathlength. In this condition, the detection limits of various compounds (ammonia, hydrogen sulphide, sulphur dioxide, benzene, toluene, ethylbenzene and p-xylene) vary between 30 and 100 mg.m-3. This UV spectrometry system has been tested with success in two applications. The first one is during gaseous ammonia dispersion, simulating a chemical accident. The sec- ond one is BTEX monitoring measurement in a process control of soil remediation. In this case, UV is associated with spectral data treatment software. All results are compared with reference methods (Nessler reagent for ammonia, gas chromatography for BTEX). An acceptable agreement was found.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"23132 1","pages":"966-972"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75584823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000162
F. Doussot, P. Pardon, J. Dedier, B. Jeso
Dry extract, ellagitanins, free ellagic acid, whisky-lactone, eugenol and vanillin have been quantified for a sample set of 61 pedunculate oaks (Quercus robur L.) and 72 sessile oaks (Quercus petraea Liebl.) originating from 6 different forests. Despite a very high interindividual variability, pedunculate oak shows higher level of dry extract, ellagitanins and free ellagic acid but lower level in volatil compounds compared to sessile oak. Inside a same species, differences between forests are less marked . Extractible compounds level is poorly correlated to the grain (ring width). Regarding cambial age, it might have its significanc e but lack of scientific data could not permit to conclude in that sense. Our results suggest that cooperage oak selection should be based on a species-provenance combination rather than on the grain or the provenance solely.
{"title":"Individual, species and geographic origin influence on cooperage oak extractible content (Quercus robur L. and Quercus petraea Liebl.)","authors":"F. Doussot, P. Pardon, J. Dedier, B. Jeso","doi":"10.1051/ANALUSIS:2000162","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000162","url":null,"abstract":"Dry extract, ellagitanins, free ellagic acid, whisky-lactone, eugenol and vanillin have been quantified for a sample set of 61 pedunculate oaks (Quercus robur L.) and 72 sessile oaks (Quercus petraea Liebl.) originating from 6 different forests. Despite a very high interindividual variability, pedunculate oak shows higher level of dry extract, ellagitanins and free ellagic acid but lower level in volatil compounds compared to sessile oak. Inside a same species, differences between forests are less marked . Extractible compounds level is poorly correlated to the grain (ring width). Regarding cambial age, it might have its significanc e but lack of scientific data could not permit to conclude in that sense. Our results suggest that cooperage oak selection should be based on a species-provenance combination rather than on the grain or the provenance solely.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"75 1","pages":"960-965"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90223593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000280934
W. Weinmann, M. Gergov, M. Goerner
Two MS/MS libraries of drugs created by electroscopy ionisation (ESI) and collision-induced dissociation (CID) of the quasimolecular ions have been developed with triple-quadrupole ion-spray mass spectrometers. for both libraries three and four different collision energies were used, rezspectively, to ontain a variety of CID spectra, which were all included separately into the MS/MS librarie. The MS/MS product ion spectraof more than 400 drugs were acquired in positive or negative mode in two labrories independetly. recently, on of these MS/MS libraries was applied successfully for the identification of drug metabolites and the other has been used for qualitative analysis of drugs in urine samples with data dependent experiments (DDE). In this work, the reproducibility of CID spectra has been tested with three instruments (including two different instruments) in three laboratories. For comparision of CID-spectra, library searching with a combination of the two libraries was performed and fit values were compared. With regard to libary fit values CID-spectra were found to be highly reproducible between the instruments, when similar CID gas pressure and collision energy were applied. In addition, the long-time reproducibility of CIS over 30 months with the API 365 was demonstrated. Furthermore, comparisions of in-source CID and CID by MS/MS was given. It can be concluded, that both MS/MS libraries created with APIs 365 can be used with both types of triple-quadrupole instruments from Sciex (API 365 and 2000) for drug identification. Two applications of these MS/MS spectra libraries in combination with data dependent experiments are summarised.
{"title":"MS/MS-libraries with triple quadrupole-tandem mass spectrometers for drug identification and drug screening","authors":"W. Weinmann, M. Gergov, M. Goerner","doi":"10.1051/ANALUSIS:2000280934","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000280934","url":null,"abstract":"Two MS/MS libraries of drugs created by electroscopy ionisation (ESI) and collision-induced dissociation (CID) of the quasimolecular ions have been developed with triple-quadrupole ion-spray mass spectrometers. for both libraries three and four different collision energies were used, rezspectively, to ontain a variety of CID spectra, which were all included separately into the MS/MS librarie. The MS/MS product ion spectraof more than 400 drugs were acquired in positive or negative mode in two labrories independetly. recently, on of these MS/MS libraries was applied successfully for the identification of drug metabolites and the other has been used for qualitative analysis of drugs in urine samples with data dependent experiments (DDE). In this work, the reproducibility of CID spectra has been tested with three instruments (including two different instruments) in three laboratories. For comparision of CID-spectra, library searching with a combination of the two libraries was performed and fit values were compared. With regard to libary fit values CID-spectra were found to be highly reproducible between the instruments, when similar CID gas pressure and collision energy were applied. In addition, the long-time reproducibility of CIS over 30 months with the API 365 was demonstrated. Furthermore, comparisions of in-source CID and CID by MS/MS was given. It can be concluded, that both MS/MS libraries created with APIs 365 can be used with both types of triple-quadrupole instruments from Sciex (API 365 and 2000) for drug identification. Two applications of these MS/MS spectra libraries in combination with data dependent experiments are summarised.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"38 1","pages":"934-941"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87480576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000280888
F. Cuyckens, Y. Ma, G. Pocsfalvi, M. Claeys
In this article we review tandem mass spectral approaches to the structural characterization of flavonoid glycosides wich are ubiquitous secondary plant metabolites. It is demonstrated how structural information on O-diglycosides can be obtained on (i) the carboydrate sequence, (ii) the aglycone part, and (iii) the linkage in the diglycosidic part. Both the positive and negative ion modes have been employed.
{"title":"Tandem mass spectral strategies for the structural characterization of flavonoid glycosides","authors":"F. Cuyckens, Y. Ma, G. Pocsfalvi, M. Claeys","doi":"10.1051/ANALUSIS:2000280888","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000280888","url":null,"abstract":"In this article we review tandem mass spectral approaches to the structural characterization of flavonoid glycosides wich are ubiquitous secondary plant metabolites. It is demonstrated how structural information on O-diglycosides can be obtained on (i) the carboydrate sequence, (ii) the aglycone part, and (iii) the linkage in the diglycosidic part. Both the positive and negative ion modes have been employed.","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"48 1","pages":"888-895"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84845799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-01DOI: 10.1051/ANALUSIS:2000280941
B. Larsen
Liquid chromatography pultiple mass spectrometry with atmospheric pressure ionisation and ion-trap instruments is a potentially useful technique for structure elucidation of polar pestcides and their degradation products. The major drawback today is the lack of spectral libraries and our limited knowledge on collision induced dissociation processes. The present paper gives an introduction to this area of research and presents interesting examples of fragmentation pathaways for protonated and deprotonated ions obtained by atmospheric pressure chemical ionisation (APCI) and electrospray ionisation (ESI).
{"title":"Ion-Trap Multiple Mass Spectrometry in Pesticide Analysis.","authors":"B. Larsen","doi":"10.1051/ANALUSIS:2000280941","DOIUrl":"https://doi.org/10.1051/ANALUSIS:2000280941","url":null,"abstract":"Liquid chromatography pultiple mass spectrometry with atmospheric pressure ionisation and ion-trap instruments is a potentially useful technique for structure elucidation of polar pestcides and their degradation products. The major drawback today is the lack of spectral libraries and our limited knowledge on collision induced dissociation processes. The present paper gives an introduction to this area of research and presents interesting examples of fragmentation pathaways for protonated and deprotonated ions obtained by atmospheric pressure chemical ionisation (APCI) and electrospray ionisation (ESI).","PeriodicalId":8221,"journal":{"name":"Analusis","volume":"46 1","pages":"941-946"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73974659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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