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Enhancing the Image Pre-Processing for Large Fleets Based on a Fuzzy Approach to Handle Multiple Resolutions 基于处理多分辨率的模糊方法加强大型车队的图像预处理
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188254
Ching-Yun Mu, Pin Kung
Image pre-processing is crucial for large fleet management. Many traffic videos are collected by closed-circuit television (CCTV), which has a fixed area monitoring for image analysis. This paper adopts the front camera installed in large vehicles to obtain moving traffic images, whereas CCTV is more limited. In practice, fleets often install cameras with different resolutions due to cost considerations. The cameras evaluate the front images with traffic lights. This paper proposes fuzzy enhancement with RGB and CIELAB conversions to handle multiple resolutions. This study provided image pre-processing adjustment comparisons, enabling further model training and analysis. This paper proposed fuzzy enhancement to deal with multiple resolutions. The fuzzy enhancement and fuzzy with brightness adjustment produced images with lower MSE and higher PSNR for the images of the front view. Fuzzy enhancement can also be used to enhance traffic light image adjustments. Moreover, this study employed You Only Look Once Version 9 (YOLOv9) for model training. YOLOv9 with fuzzy enhancement obtained better detection performance. This fuzzy enhancement made more flexible adjustments for pre-processing tasks and provided guidance for fleet managers to perform consistent image-enhancement adjustments for handling multiple resolutions.
图像预处理对于大型车队管理至关重要。许多交通视频都是通过闭路电视(CCTV)采集的,它有一个固定的区域监控来进行图像分析。本文采用安装在大型车辆上的前置摄像头来获取移动的交通图像,而闭路电视的局限性较大。在实际应用中,出于成本考虑,车队通常会安装不同分辨率的摄像头。这些摄像头通过交通信号灯对前方图像进行评估。本文提出使用 RGB 和 CIELAB 转换进行模糊增强,以处理多种分辨率。本研究提供了图像预处理调整比较,以便进一步进行模型训练和分析。本文提出了处理多种分辨率的模糊增强技术。模糊增强和带有亮度调整的模糊处理所生成的图像,正面图像的 MSE 更低,PSNR 更高。模糊增强还可用于交通灯图像的增强调整。此外,本研究还采用了 You Only Look Once Version 9(YOLOv9)进行模型训练。经过模糊增强的 YOLOv9 获得了更好的检测性能。这种模糊增强技术为预处理任务提供了更灵活的调整,并为车队管理人员在处理多种分辨率时执行一致的图像增强调整提供了指导。
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引用次数: 0
Versatile Video Coding-Post Processing Feature Fusion: A Post-Processing Convolutional Neural Network with Progressive Feature Fusion for Efficient Video Enhancement 多功能视频编码--后处理特征融合:后处理卷积神经网络与渐进式特征融合实现高效视频增强
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188276
Tanni Das, Xilong Liang, Kiho Choi
Advanced video codecs such as High Efficiency Video Coding/H.265 (HEVC) and Versatile Video Coding/H.266 (VVC) are vital for streaming high-quality online video content, as they compress and transmit data efficiently. However, these codecs can occasionally degrade video quality by adding undesirable artifacts such as blockiness, blurriness, and ringing, which can detract from the viewer’s experience. To ensure a seamless and engaging video experience, it is essential to remove these artifacts, which improves viewer comfort and engagement. In this paper, we propose a deep feature fusion based convolutional neural network (CNN) architecture (VVC-PPFF) for post-processing approach to further enhance the performance of VVC. The proposed network, VVC-PPFF, harnesses the power of CNNs to enhance decoded frames, significantly improving the coding efficiency of the state-of-the-art VVC video coding standard. By combining deep features from early and later convolution layers, the network learns to extract both low-level and high-level features, resulting in more generalized outputs that adapt to different quantization parameter (QP) values. The proposed VVC-PPFF network achieves outstanding performance, with Bjøntegaard Delta Rate (BD-Rate) improvements of 5.81% and 6.98% for luma components in random access (RA) and low-delay (LD) configurations, respectively, while also boosting peak signal-to-noise ratio (PSNR).
高效视频编码/H.265 (HEVC) 和多功能视频编码/H.266 (VVC) 等高级视频编解码器对流式传输高质量在线视频内容至关重要,因为它们能有效地压缩和传输数据。然而,这些编解码器偶尔也会因添加块状、模糊和振铃等不良伪像而降低视频质量,从而影响观众的观看体验。为了确保无缝和引人入胜的视频体验,必须消除这些人工痕迹,从而提高观众的舒适度和参与度。在本文中,我们提出了一种基于深度特征融合的卷积神经网络(CNN)架构(VVC-PPFF),用于后处理方法,以进一步提高 VVC 的性能。所提出的网络(VVC-PPFF)利用 CNN 的强大功能来增强解码帧,从而显著提高了最先进的 VVC 视频编码标准的编码效率。通过结合早期卷积层和后期卷积层的深度特征,该网络学会了提取低层次和高层次特征,从而产生了适应不同量化参数(QP)值的更具通用性的输出。所提出的 VVC-PPFF 网络性能卓越,在随机存取(RA)和低延迟(LD)配置中,卢玛分量的比昂特加德Δ率(BD-Rate)分别提高了 5.81% 和 6.98%,同时还提高了峰值信噪比(PSNR)。
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引用次数: 0
Comprehensive Insights into the Molecular Basis of HIV Glycoproteins 全面了解艾滋病毒糖蛋白的分子基础
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188271
Amir Elalouf, Hanan Maoz, Amit Yaniv Rosenfeld
Human Immunodeficiency Virus (HIV) is a diploid, C-type enveloped retrovirus belonging to the Lentivirus genus, characterized by two positive-sense single-stranded RNA genomes, that transitioned from non-human primates to humans and has become globally widespread. In its advanced stages, HIV leads to Acquired Immune Deficiency Syndrome (AIDS), which severely weakens the immune system by depleting CD4+ helper T cells. Without treatment, HIV progressively impairs immune function, making the body susceptible to various opportunistic infections and complications, including cardiovascular, respiratory, and neurological issues, as well as secondary cancers. The envelope glycoprotein complex (Env), composed of gp120 and gp41 subunits derived from the precursor gp160, plays a central role in cycle entry. gp160, synthesized in the rough endoplasmic reticulum, undergoes glycosylation and proteolytic cleavage, forming a trimeric spike on the virion surface. These structural features, including the transmembrane domain (TMD), membrane-proximal external region (MPER), and cytoplasmic tail (CT), are critical for viral infectivity and immune evasion. Glycosylation and proteolytic processing, especially by furin, are essential for Env’s fusogenic activity and capacity to evade immune detection. The virus’s outer envelope glycoprotein, gp120, interacts with host cell CD4 receptors. This interaction, along with the involvement of coreceptors CXCR4 and CCR5, prompts the exposure of the gp41 fusogenic components, enabling the fusion of viral and host cell membranes. While this is the predominant pathway for viral entry, alternative mechanisms involving receptors such as C-type lectin and mannose receptors have been found. This review aims to provide an in-depth analysis of the structural features and functional roles of HIV entry proteins, particularly gp120 and gp41, in the viral entry process. By examining these proteins’ architecture, the review elucidates how their structural properties facilitate HIV invasion of host cells. It also explores the synthesis, trafficking, and structural characteristics of Env/gp160 proteins, highlighting the interactions between gp120, gp41, and the viral matrix. These contributions advance drug resistance management and vaccine development efforts.
人类免疫缺陷病毒(HIV)是一种二倍体 C 型包膜逆转录病毒,属于慢病毒属,具有两个正义单链 RNA 基因组。艾滋病病毒晚期会导致获得性免疫缺陷综合症(AIDS),CD4+辅助性 T 细胞耗竭,严重削弱免疫系统。如果不进行治疗,艾滋病毒会逐渐损害免疫功能,使人体容易受到各种机会性感染和并发症的影响,包括心血管、呼吸和神经系统问题,以及继发性癌症。包膜糖蛋白复合物(Env)由前体 gp160 衍生出的 gp120 和 gp41 亚基组成,在病毒进入循环过程中起着核心作用。gp160 在粗面内质网中合成,经过糖基化和蛋白水解,在病毒表面形成三聚体尖峰。这些结构特征包括跨膜结构域(TMD)、膜近端外部区域(MPER)和胞质尾(CT),对于病毒的感染性和免疫逃避至关重要。糖基化和蛋白水解加工,尤其是呋喃蛋白的加工,对 Env 的致熔活性和逃避免疫检测的能力至关重要。病毒外包膜糖蛋白 gp120 与宿主细胞 CD4 受体相互作用。这种相互作用以及核心受体 CXCR4 和 CCR5 的参与,促使 gp41 致熔成分暴露,从而使病毒和宿主细胞膜融合。虽然这是病毒进入的主要途径,但也发现了涉及 C 型凝集素和甘露糖受体等受体的替代机制。本综述旨在深入分析 HIV 进入蛋白(尤其是 gp120 和 gp41)在病毒进入过程中的结构特征和功能作用。通过研究这些蛋白的结构,综述阐明了它们的结构特性是如何促进 HIV 入侵宿主细胞的。综述还探讨了Env/gp160蛋白的合成、贩运和结构特征,重点介绍了gp120、gp41和病毒基质之间的相互作用。这些贡献推动了耐药性管理和疫苗开发工作。
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引用次数: 0
Hybrid Artificial Protozoa-Based JADE for Attack Detection 基于混合人工原生动物的攻击检测 JADE
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188280
Ahmad k. Al Hwaitat, Hussam N. Fakhouri
This paper presents a novel hybrid optimization algorithm that combines JADE Adaptive Differential Evolution with Artificial Protozoa Optimizer (APO) to solve complex optimization problems and detect attacks. The proposed Hybrid APO-JADE Algorithm leverages JADE’s adaptive exploration capabilities and APO’s intensive exploitation strategies, ensuring a robust search process that balances global and local optimization. Initially, the algorithm employs JADE’s mutation and crossover operations, guided by adaptive control parameters, to explore the search space and prevent premature convergence. As the optimization progresses, a dynamic transition to the APO mechanism is implemented, where Levy flights and adaptive change factors are utilized to refine the best solutions identified during the exploration phase. This integration of exploration and exploitation phases enhances the algorithm’s ability to converge to high-quality solutions efficiently. The performance of the APO-JADE was verified via experimental simulations and compared with state-of-the-art algorithms using the 2022 IEEE Congress on Evolutionary Computation benchmark (CEC) 2022 and 2021. Results indicate that APO-JADE achieved outperforming results compared with the other algorithms. Considering practicality, the proposed APO-JADE was used to solve a real-world application in attack detection and tested on DS2OS, UNSW-NB15, and ToNIoT datasets, demonstrating its robust performance.
本文提出了一种新颖的混合优化算法,它将 JADE 自适应差分进化算法与人工原生动物优化器 (APO) 相结合,用于解决复杂的优化问题和检测攻击。所提出的 APO-JADE 混合算法充分利用了 JADE 的自适应探索能力和 APO 的密集开发策略,确保了搜索过程的稳健性,并兼顾了全局和局部优化。最初,该算法在自适应控制参数的指导下,利用 JADE 的突变和交叉操作来探索搜索空间,防止过早收敛。随着优化进程的推进,算法会动态过渡到 APO 机制,利用列维飞行和自适应变化因素来完善探索阶段确定的最佳解决方案。这种探索和利用阶段的整合增强了算法高效收敛到高质量解决方案的能力。通过实验模拟验证了 APO-JADE 的性能,并使用 2022 年和 2021 年 IEEE 进化计算大会基准(CEC)与最先进的算法进行了比较。结果表明,APO-JADE 取得了优于其他算法的结果。考虑到实用性,提议的 APO-JADE 被用于解决攻击检测中的实际应用,并在 DS2OS、UNSW-NB15 和 ToNIoT 数据集上进行了测试,证明了其稳健的性能。
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引用次数: 0
Examining the Relationship between Psychological and Functional Status after a Sports Musculoskeletal Injury 研究运动性肌肉骨骼损伤后心理和功能状态之间的关系
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188258
Konstantinos Parlakidis, Dimitrios Krokos, Maria-Louiza Sagredaki, Lazaros Alexandros Kontopoulos, Anna Christakou
The purpose of the present study was to investigate the relationship between re-injury worry, confidence, and attention and athletes’ functional status upon returning to sport after an injury. The sample consisted of 28 amateur-level male football players, aged 18 to 35 years, with a previous lower-limb injury. The athletes followed a physiotherapy rehabilitation program and completed three valid questionnaires examining re-injury worry, sport confidence, and attention returning to sport. The sample also performed three functional tests: (a) single-leg hop for distance, (b) side hop, and (c) the vertical jump. The results showed high correlations between the psychological factors between the functional tests. Physiotherapy duration was positively highly correlated with the time of absence from sport and severity of injury. The severity of the injury was also positively highly correlated with the time of absence from sport. The factors “Functional Attention” and “Distraction Attention” showed a positive and negative correlation with the single-leg hop for distance and the vertical jump, respectively. Athletes with a grade II severity injury showed greater attention compared to grade III severity injury. The increased level of re-injury worry was positively related to “Distraction Attention” and negatively related to the functional ability of the injured limb. The psychological readiness was partially related to the athletes’ functional status. The present study reports the importance of psychological readiness and its relationship with athletes’ functional status of returning to sport following a musculoskeletal sport injury.
本研究的目的是调查再次受伤的担忧、信心和注意力与运动员受伤后重返运动场时的功能状态之间的关系。样本包括 28 名业余水平的男性足球运动员,年龄在 18 至 35 岁之间,下肢曾受过伤。这些运动员接受了理疗康复计划,并填写了三份有效问卷,调查他们对再次受伤的担忧、运动信心以及重返运动场后的注意力。样本还进行了三项功能测试:(a)单腿跳远、(b)侧跳和(c)纵跳。结果显示,心理因素与功能测试之间存在高度相关性。物理治疗时间与缺席运动时间和受伤严重程度呈高度正相关。受伤的严重程度也与离开运动场的时间呈高度正相关。功能注意力 "和 "分心注意力 "分别与单脚跳远和立定跳远呈正相关和负相关。受伤严重程度为二级的运动员与受伤严重程度为三级的运动员相比,注意力更集中。担心再次受伤的程度增加与 "注意力分散 "呈正相关,而与受伤肢体的功能能力呈负相关。心理准备程度与运动员的功能状态有部分关系。本研究报告了心理准备的重要性及其与运动员在肌肉骨骼运动损伤后重返运动场的功能状态之间的关系。
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引用次数: 0
Multiphysics Optimization of a High-Speed Permanent Magnet Motor Based on Subspace and Sequential Strategy 基于子空间和序列策略的高速永磁电机多物理场优化
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188267
Honglin Yan, Guanghui Du, Wentao Gao, Yanhong Chen, Cunlong Cui, Kai Xu
In the optimization of high-speed permanent magnet motors (HSPMMs), electromagnetic characteristics, rotor stress, rotor dynamics, and temperature characteristics must all be considered simultaneously, and there are numerous optimization parameters for both the stator and rotor. These factors pose significant challenges to the multiphysics optimization of HSPMMs. Therefore, this paper presents a multiphysics optimization process for the HSPMM of 60 kW 30,000 rpm by combining subspace strategy and sequential strategy to mitigate the issues of high training volume and mutual coupling. Ten optimization parameters of stator and rotor are determined firstly. Then, using finite element analysis of rotor stress and rotor dynamics, the range of values for critical parameters of the rotor is established. Next, in the electromagnetic optimization, the process is divided into rotor parameter subspace and stator parameter subspace according to the subspace optimization strategy. The temperature field is also checked based on the optimization results. Finally, a prototype is manufactured and the comprehensive performance is tested to validate the multiphysics optimization process.
在优化高速永磁电机(HSPMMs)时,必须同时考虑电磁特性、转子应力、转子动力学和温度特性,而且定子和转子都有许多优化参数。这些因素给 HSPMM 的多物理场优化带来了巨大挑战。因此,本文针对 60 kW 30,000 rpm 的 HSPMM 提出了一种多物理场优化流程,将子空间策略和顺序策略相结合,以缓解高训练量和相互耦合的问题。首先确定了定子和转子的十个优化参数。然后,通过对转子应力和转子动力学的有限元分析,确定了转子关键参数的取值范围。接下来,在电磁优化过程中,根据子空间优化策略,将优化过程划分为转子参数子空间和定子参数子空间。此外,还根据优化结果检查了温度场。最后,制造原型并测试其综合性能,以验证多物理场优化过程。
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引用次数: 0
Carbon Emission Analysis of Low-Carbon Technology Coupled with a Regional Integrated Energy System Considering Carbon-Peaking Targets 考虑碳排放目标的低碳技术与区域综合能源系统的碳排放分析
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188277
Yipu Zeng, Yiru Dai, Yiming Shu, Ting Yin
Analyzing the carbon emission behavior of a regional integrated energy system (RIES) is crucial for aligning with carbon-peaking development strategies and ensuring compliance with carbon-peaking implementation pathways. This study focuses on a building cluster area in Shanghai, China, aiming to provide a comprehensive analysis from both macro and micro perspectives. From a macro viewpoint, an extended STIRPAT model, incorporating the environmental Kuznets curve, is proposed to predict the carbon-peaking trajectory in Shanghai. This approach yields carbon-peaking implementation pathways for three scenarios: rapid development, stable development, and green development, spanning the period of 2020–2040. At a micro scale, three distinct RIES system configurations—fossil, hybrid, and clean—are formulated based on the renewable energy penetration level. Utilizing a multi-objective optimization model, this study explores the carbon emission behavior of a RIES while adhering to carbon-peaking constraints. Four scenarios of carbon emission reduction policies are implemented, leveraging green certificates and carbon-trading mechanisms. Performance indicators, including carbon emissions, carbon intensity, and marginal emission reduction cost, are employed to scrutinize the carbon emission behavior of the cross-regional integrated energy system within the confines of carbon peaking.
分析区域综合能源系统(RIES)的碳排放行为对于配合碳排放发展战略、确保符合碳排放实施路径至关重要。本研究以中国上海的一个建筑集群区域为研究对象,旨在从宏观和微观两个角度进行综合分析。从宏观角度出发,提出了一个包含环境库兹涅茨曲线的扩展 STIRPAT 模型,以预测上海的碳排放轨迹。该方法得出了 2020-2040 年期间快速发展、稳定发展和绿色发展三种情景下的碳排放实施路径。在微观尺度上,根据可再生能源的渗透水平,制定了三种不同的 RIES 系统配置--化石能源、混合能源和清洁能源。本研究利用多目标优化模型,探讨了可再生能源系统在遵守碳排放约束条件下的碳排放行为。利用绿色证书和碳交易机制,实施了四种碳减排政策方案。研究采用了碳排放量、碳强度和边际减排成本等绩效指标,以考察跨区域综合能源系统在碳峰值约束下的碳排放行为。
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引用次数: 0
Fast Fault Line Selection Technology of Distribution Network Based on MCECA-CloFormer 基于 MCECA-CloFormer 的配电网络快速故障选线技术
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188270
Can Ding, Pengcheng Ma, Changhua Jiang, Fei Wang
When a single-phase grounding fault occurs in resonant ground distribution network, the fault characteristics are weak and it is difficult to detect the fault line. Therefore, a fast fault line selection method based on MCECA-CloFormer is proposed in this paper. Firstly, zero-sequence current signals were converted into images using the moving average filter method and motif difference field to construct fault data set. Then, the ECA module was modified to MCECA (MultiCNN-ECA) so that it can accept data input from multiple measurement points. Secondly, the lightweight model CloFormer was used in the back end of MCECA module to further perceive the feature map and complete the establishment of the line selection model. Finally, the line selection model was trained, and the information such as model weight was saved. The simulation results demonstrated that the pre-trained MCECA-CloFormer achieved a line selection accuracy of over 98% under 10 dB noise, with a remarkably low single fault processing time of approximately 0.04 s. Moreover, it exhibited suitability for arc high-resistance grounding faults, data-missing cases, neutral-point ungrounded systems, and active distribution networks. In addition, the method was still valid when tested with actual field recording data.
当谐振接地配电网发生单相接地故障时,故障特征较弱,很难检测到故障线路。因此,本文提出了一种基于 MCECA-CloFormer 的快速故障选线方法。首先,利用移动平均滤波法和动差场将零序电流信号转换为图像,构建故障数据集。然后,将 ECA 模块修改为 MCECA(MultiCNN-ECA),使其可以接受来自多个测量点的数据输入。其次,在 MCECA 模块后端使用轻量级模型 CloFormer 进一步感知特征图,完成选线模型的建立。最后,对选线模型进行训练,并保存模型权重等信息。仿真结果表明,预训练的 MCECA-CloFormer 在 10 dB 噪声下的选线准确率达到 98% 以上,单次故障处理时间仅为 0.04 s 左右。此外,在使用实际现场记录数据进行测试时,该方法仍然有效。
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引用次数: 0
Azimuthal Solar Synchronization and Aerodynamic Neuro-Optimization: An Empirical Study on Slime-Mold-Inspired Neural Networks for Solar UAV Range Optimization 方位太阳同步和空气动力神经优化:用于太阳能无人飞行器航程优化的 Slime-Mold 激励型神经网络实证研究
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188265
Graheeth Hazare, Mohamed Thariq Hameed Sultan, Dariusz Mika, Farah Syazwani Shahar, Grzegorz Skorulski, Marek Nowakowski, Andriy Holovatyy, Ile Mircheski, Wojciech Giernacki
This study introduces a novel methodology for enhancing the efficiency of solar-powered unmanned aerial vehicles (UAVs) through azimuthal solar synchronization and aerodynamic neuro-optimization, leveraging the principles of slime mold neural networks. The objective is to broaden the operational capabilities of solar UAVs, enabling them to perform over extended ranges and in varied weather conditions. Our approach integrates a computational model of slime mold networks with a simulation environment to optimize both the solar energy collection and the aerodynamic performance of UAVs. Specifically, we focus on improving the UAVs’ aerodynamic efficiency in flight, aligning it with energy optimization strategies to ensure sustained operation. The findings demonstrated significant improvements in the UAVs’ range and weather resilience, thereby enhancing their utility for a variety of missions, including environmental monitoring and search and rescue operations. These advancements underscore the potential of integrating biomimicry and neural-network-based optimization in expanding the functional scope of solar UAVs.
本研究介绍了一种新方法,利用粘菌神经网络原理,通过方位太阳同步和空气动力神经优化,提高太阳能无人飞行器(UAV)的效率。我们的目标是拓宽太阳能无人飞行器的作战能力,使其能够在各种天气条件下进行远距离飞行。我们的方法将粘菌网络计算模型与仿真环境相结合,以优化无人机的太阳能收集和空气动力性能。具体来说,我们的重点是提高无人飞行器在飞行过程中的空气动力效率,并将其与能源优化策略相结合,以确保持续运行。研究结果表明,无人机的航程和天气适应能力有了显著提高,从而增强了其在环境监测和搜救行动等各种任务中的实用性。这些进步凸显了将生物仿生学和基于神经网络的优化相结合,扩大太阳能无人机功能范围的潜力。
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引用次数: 0
Contamination in Bone Substitute Materials: A Systematic Review 骨替代材料中的污染:系统回顾
Q1 Mathematics Pub Date : 2024-09-13 DOI: 10.3390/app14188266
Natalia Struzik, Julia Kensy, Paweł J. Piszko, Jan Kiryk, Kamila Wiśniewska, Sylwia Kiryk, Łuksza Korjat, Tomasz Horodniczy, Paulina Sobierajska, Jacek Matys, Rafal J. Wiglusz, Maciej Dobrzyński
Objective: Bone augmentation has become a significant practice in various areas of bone regeneration dentistry. This systematic review analyzes the research focused on evaluating bone substitute materials for the presence of contaminants. Methods: In June 2024, an extensive electronic search was conducted using renowned databases such as PubMed, Web of Science, and Scopus. Specific keywords employed in the search included ((bone AND (substitute) AND (remnants OR (purity)) OR ((graft AND tooth) AND (remnants OR purity)) OR ((graft AND dentin) AND (remnants OR purity)). The search adhered to the PRISMA protocol and the PICO framework. The review concentrated on the origin of bone substitute materials, the processing methods used for these materials, techniques for assessing purity, and types of contamination identified. A total of 594 articles were identified of which 22 met the criteria and were incorporated into the review. Results: Investigations into allogeneic and xenogeneic bone substitute materials have revealed that, despite manufacturers’ assurances of purity, some materials still contain contaminants. Sample analyses demonstrated the presence of donor cellular remains, cellular debris, intertrabecular fat, connective tissue, and collagen. Similarly, synthetically produced bone substitute materials (alloplastic materials) contained various impurities, such as polyvinyl alcohol (PVA), CaO phases, calcium-deficient HAp phases, oily substances containing carbon and silicone, cellulose derivatives, alpha-tricalcium phosphate (α-TCP), and heavy metals. Conclusions: Bone-derived and bone-like graft materials can contain various organic and inorganic impurities.
目的:骨增量已成为骨再生牙科各个领域的重要实践。本系统综述分析了有关骨替代材料污染物评估的研究。研究方法2024 年 6 月,我们使用 PubMed、Web of Science 和 Scopus 等知名数据库进行了广泛的电子检索。搜索中使用的特定关键词包括((骨和(替代物)和(残留物或(纯度))或((移植物和牙齿)和(残留物或纯度))或((移植物和牙本质)和(残留物或纯度))。检索遵循了 PRISMA 协议和 PICO 框架。综述主要集中在骨替代材料的来源、这些材料的加工方法、评估纯度的技术以及已确定的污染类型。共确定了 594 篇文章,其中 22 篇符合标准并纳入了综述。结果:对异体和异种骨替代材料的调查显示,尽管制造商保证了材料的纯度,但有些材料仍含有污染物。样本分析表明存在供体细胞残骸、细胞碎片、小梁间脂肪、结缔组织和胶原蛋白。同样,人工合成的骨替代材料(异体材料)也含有各种杂质,如聚乙烯醇(PVA)、氧化钙相、缺钙的 HAp 相、含碳和硅的油性物质、纤维素衍生物、α-磷酸三钙(α-TCP)和重金属。结论骨源和类骨接枝材料可能含有各种有机和无机杂质。
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引用次数: 0
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